RGSL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)5.08994325
2indolalkylamine metabolic process (GO:0006586)4.72877725
3indole-containing compound catabolic process (GO:0042436)4.71034357
4indolalkylamine catabolic process (GO:0046218)4.71034357
5tryptophan catabolic process (GO:0006569)4.71034357
6regulation of dendritic cell antigen processing and presentation (GO:0002604)4.70240818
7sperm motility (GO:0030317)4.54959122
8mesenchymal cell differentiation involved in renal system development (GO:2001012)4.43300864
9mesenchymal cell differentiation involved in kidney development (GO:0072161)4.43300864
10mature B cell differentiation involved in immune response (GO:0002313)4.37680354
11kynurenine metabolic process (GO:0070189)4.36127397
12acrosome reaction (GO:0007340)4.32761080
13detection of light stimulus involved in sensory perception (GO:0050962)4.27502231
14detection of light stimulus involved in visual perception (GO:0050908)4.27502231
15multicellular organism reproduction (GO:0032504)4.23792789
16cilium or flagellum-dependent cell motility (GO:0001539)4.15011445
17detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)4.10056661
18L-fucose catabolic process (GO:0042355)4.03553184
19fucose catabolic process (GO:0019317)4.03553184
20L-fucose metabolic process (GO:0042354)4.03553184
21motile cilium assembly (GO:0044458)4.00132714
22tryptophan metabolic process (GO:0006568)3.97638386
23behavioral response to ethanol (GO:0048149)3.93723081
24microtubule depolymerization (GO:0007019)3.83765150
25neural tube formation (GO:0001841)3.81417662
26tachykinin receptor signaling pathway (GO:0007217)3.80340658
27fusion of sperm to egg plasma membrane (GO:0007342)3.77078000
28germinal center formation (GO:0002467)3.76257715
29superoxide anion generation (GO:0042554)3.76150918
30regulation of cilium movement (GO:0003352)3.75834745
31photoreceptor cell maintenance (GO:0045494)3.75248711
32cellular ketone body metabolic process (GO:0046950)3.72384126
33retinal cone cell development (GO:0046549)3.65338673
34indole-containing compound metabolic process (GO:0042430)3.64177959
35axonemal dynein complex assembly (GO:0070286)3.62850052
36T-helper 1 type immune response (GO:0042088)3.58461198
37detection of other organism (GO:0098543)3.54431646
38mature B cell differentiation (GO:0002335)3.51652085
39positive regulation of antigen processing and presentation (GO:0002579)3.45192562
40sperm-egg recognition (GO:0035036)3.43024020
41cell wall macromolecule metabolic process (GO:0044036)3.40675986
42cell wall macromolecule catabolic process (GO:0016998)3.40675986
43negative regulation of cytosolic calcium ion concentration (GO:0051481)3.36852111
44ketone body metabolic process (GO:1902224)3.34575649
45serotonin metabolic process (GO:0042428)3.34448798
46regulation of antigen processing and presentation (GO:0002577)3.33163434
47protein polyglutamylation (GO:0018095)3.33017010
48gamma-aminobutyric acid transport (GO:0015812)3.32262159
49detection of bacterium (GO:0016045)3.30206178
50positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)3.29863650
51establishment of protein localization to Golgi (GO:0072600)3.29266998
52cell-cell recognition (GO:0009988)3.26387614
53epithelial cilium movement (GO:0003351)3.24858148
54behavioral response to nicotine (GO:0035095)3.24031447
55primary amino compound metabolic process (GO:1901160)3.21303312
56reproduction (GO:0000003)3.20548008
57replicative senescence (GO:0090399)3.17865030
58membrane depolarization during action potential (GO:0086010)3.15880312
59plasma membrane fusion (GO:0045026)3.15171325
60regulation of synapse maturation (GO:0090128)3.14110047
61neuronal action potential (GO:0019228)3.13673343
62amine catabolic process (GO:0009310)3.10550063
63cellular biogenic amine catabolic process (GO:0042402)3.10550063
64piRNA metabolic process (GO:0034587)3.08915863
65reflex (GO:0060004)3.03929084
66DNA synthesis involved in DNA repair (GO:0000731)3.02596286
67benzene-containing compound metabolic process (GO:0042537)2.98769440
68defense response to protozoan (GO:0042832)2.95700161
69positive regulation of cellular amide metabolic process (GO:0034250)2.95503659
70postsynaptic membrane organization (GO:0001941)2.95502390
71dendritic cell chemotaxis (GO:0002407)2.94485459
72epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.93590528
73immunoglobulin mediated immune response (GO:0016064)2.92662519
74B cell mediated immunity (GO:0019724)2.92211727
75rhodopsin mediated signaling pathway (GO:0016056)2.91807171
76glucosamine-containing compound catabolic process (GO:1901072)2.91344072
77signal peptide processing (GO:0006465)2.91263178
78centriole assembly (GO:0098534)2.90050104
79axoneme assembly (GO:0035082)2.89900743
80DNA deamination (GO:0045006)2.89289349
81acrosome assembly (GO:0001675)2.88824977
82C4-dicarboxylate transport (GO:0015740)2.88429406
83binding of sperm to zona pellucida (GO:0007339)2.86394639
84regulation of cellular extravasation (GO:0002691)2.84179439
85negative regulation of mast cell activation (GO:0033004)2.84006735
86regulation of rhodopsin mediated signaling pathway (GO:0022400)2.83640447
87antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.82575517
88L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.82394316
89negative regulation of DNA-dependent DNA replication (GO:2000104)2.81543880
90regulation of nuclear cell cycle DNA replication (GO:0033262)2.81313474
91proline transport (GO:0015824)2.80733590
92regulation of activation of Janus kinase activity (GO:0010533)2.80039791
93NAD biosynthetic process (GO:0009435)2.78869012
94cilium organization (GO:0044782)2.77005792
95cilium movement (GO:0003341)2.76569719
96regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.75043558
97water-soluble vitamin biosynthetic process (GO:0042364)2.74803241
98spermatid development (GO:0007286)2.74753502
99glycosphingolipid biosynthetic process (GO:0006688)2.74459247
100single fertilization (GO:0007338)2.73870633
101cerebral cortex radially oriented cell migration (GO:0021799)2.73732047
102regulation of action potential (GO:0098900)2.71747840
103glycosphingolipid catabolic process (GO:0046479)2.71499932
104cilium assembly (GO:0042384)2.71310976
105DNA methylation involved in gamete generation (GO:0043046)2.71080104
106regulation of double-strand break repair via homologous recombination (GO:0010569)2.70472449
107regulation of hippo signaling (GO:0035330)2.70459574
108cilium morphogenesis (GO:0060271)2.69753929
109kidney morphogenesis (GO:0060993)2.69631528
110aromatic amino acid family catabolic process (GO:0009074)2.69174380
111regulation of sarcomere organization (GO:0060297)2.69173503
112photoreceptor cell development (GO:0042461)2.69029347
113CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.68404182
114T-helper cell differentiation (GO:0042093)2.68404182
115protein targeting to Golgi (GO:0000042)2.67984792
116auditory receptor cell stereocilium organization (GO:0060088)2.66115183
117platelet dense granule organization (GO:0060155)2.65015487
118regulation of RIG-I signaling pathway (GO:0039535)2.64693283
119neurotransmitter-gated ion channel clustering (GO:0072578)2.64629434
120positive regulation of monocyte chemotaxis (GO:0090026)2.64406943
121kinetochore assembly (GO:0051382)2.62503810
122phasic smooth muscle contraction (GO:0014821)2.61636691
123male meiosis (GO:0007140)2.61374627
124aromatic amino acid family metabolic process (GO:0009072)2.60181754
125sleep (GO:0030431)2.59361340
126dendritic cell migration (GO:0036336)2.59228422
127protein localization to cilium (GO:0061512)2.58733412
128DNA double-strand break processing (GO:0000729)2.58442930
129dopamine transport (GO:0015872)2.58040912
130transmission of nerve impulse (GO:0019226)2.57292633
131regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)2.56331704
132detection of mechanical stimulus involved in sensory perception (GO:0050974)2.54788119
133regulation of pigment cell differentiation (GO:0050932)2.54581728
134response to peptidoglycan (GO:0032494)2.52041648
135cornea development in camera-type eye (GO:0061303)2.51513060
136cAMP catabolic process (GO:0006198)2.50101050
137G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.49975057
138detection of chemical stimulus involved in sensory perception of smell (GO:0050911)2.48666057
139regulation of collateral sprouting (GO:0048670)2.47956941
140cellular response to sterol (GO:0036315)2.47587490
141neuronal action potential propagation (GO:0019227)2.47049858
142positive regulation of T-helper 1 type immune response (GO:0002827)2.46984591
143ceramide catabolic process (GO:0046514)2.46507804
144presynaptic membrane assembly (GO:0097105)2.46195065
145intra-S DNA damage checkpoint (GO:0031573)2.46175474
146positive regulation of oligodendrocyte differentiation (GO:0048714)2.46160053
147seminiferous tubule development (GO:0072520)2.45400275
148inner ear receptor stereocilium organization (GO:0060122)2.45302109
149cellular response to interleukin-15 (GO:0071350)2.45188805
150positive regulation of developmental pigmentation (GO:0048087)2.44394895
151retrograde transport, vesicle recycling within Golgi (GO:0000301)2.44164891
152eye photoreceptor cell development (GO:0042462)2.43891944
153amino acid salvage (GO:0043102)2.43670092
154L-methionine salvage (GO:0071267)2.43670092
155L-methionine biosynthetic process (GO:0071265)2.43670092
156facial nerve structural organization (GO:0021612)2.43448759
157positive regulation of interleukin-12 production (GO:0032735)2.43423627
158embryonic epithelial tube formation (GO:0001838)2.42191023
159double-strand break repair via homologous recombination (GO:0000724)2.42104306
160recombinational repair (GO:0000725)2.40873692
161regulation of male gonad development (GO:2000018)2.40838413
162protein K11-linked deubiquitination (GO:0035871)2.40728514
163adaptation of signaling pathway (GO:0023058)2.40408249
164tRNA methylation (GO:0030488)2.40040400
165regulation of mitotic spindle checkpoint (GO:1903504)2.39538741
166regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.39538741
167oxidative demethylation (GO:0070989)2.39435053
168visual perception (GO:0007601)2.39020844
169regulation of timing of cell differentiation (GO:0048505)2.37960365
170sensory perception of light stimulus (GO:0050953)2.37926517
171regulation of T-helper 1 cell differentiation (GO:0045625)2.37755770
172startle response (GO:0001964)2.36298070
173amino sugar catabolic process (GO:0046348)2.36157110
174response to protozoan (GO:0001562)2.36152360
175glycolipid catabolic process (GO:0019377)2.36147974
176replication fork processing (GO:0031297)2.33784837
177sequestering of actin monomers (GO:0042989)2.32870377
178regulation of mast cell activation (GO:0033003)2.32386093
179regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.31620457
180cellular response to exogenous dsRNA (GO:0071360)2.31012958
181I-kappaB kinase/NF-kappaB signaling (GO:0007249)2.30988558
182protein heterotetramerization (GO:0051290)2.29110201
183positive regulation of interleukin-10 production (GO:0032733)2.28013703
184cell differentiation involved in metanephros development (GO:0072202)2.26216201
185histone H2A acetylation (GO:0043968)2.25132067
186alpha-beta T cell activation involved in immune response (GO:0002287)2.24870071

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.12020974
2GBX2_23144817_ChIP-Seq_PC3_Human3.46763553
3EZH2_22144423_ChIP-Seq_EOC_Human3.38300091
4ZNF274_21170338_ChIP-Seq_K562_Hela3.20462825
5GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.09939534
6PCGF2_27294783_Chip-Seq_ESCs_Mouse2.92797537
7FLI1_27457419_Chip-Seq_LIVER_Mouse2.92413127
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.72845785
9MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.40953308
10MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.26569012
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.23864510
12SUZ12_27294783_Chip-Seq_NPCs_Mouse2.20300305
13NFE2_27457419_Chip-Seq_LIVER_Mouse2.19718290
14CTBP1_25329375_ChIP-Seq_LNCAP_Human2.19030073
15CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.15422571
16IRF8_22096565_ChIP-ChIP_GC-B_Human2.13028615
17PCGF2_27294783_Chip-Seq_NPCs_Mouse2.07300237
18AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.98087958
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.92730573
20IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.89765172
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.87747081
22P53_22387025_ChIP-Seq_ESCs_Mouse1.84949667
23TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.83951959
24BCAT_22108803_ChIP-Seq_LS180_Human1.83520868
25NANOG_18555785_Chip-Seq_ESCs_Mouse1.82611903
26POU3F2_20337985_ChIP-ChIP_501MEL_Human1.82075609
27GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.81226313
28EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.80850668
29CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.80577806
30STAT3_18555785_Chip-Seq_ESCs_Mouse1.80235759
31STAT3_23295773_ChIP-Seq_U87_Human1.80122779
32SUZ12_18555785_Chip-Seq_ESCs_Mouse1.78428630
33EZH2_27294783_Chip-Seq_NPCs_Mouse1.75948080
34NMYC_18555785_Chip-Seq_ESCs_Mouse1.75370877
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.74001842
36E2F1_18555785_Chip-Seq_ESCs_Mouse1.73349411
37* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.71632051
38IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.69945319
39CBP_20019798_ChIP-Seq_JUKART_Human1.69945319
40SOX2_18555785_Chip-Seq_ESCs_Mouse1.68954234
41EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.68566473
42TAF15_26573619_Chip-Seq_HEK293_Human1.68538198
43* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.68417797
44CMYC_18555785_Chip-Seq_ESCs_Mouse1.65661888
45PU1_27457419_Chip-Seq_LIVER_Mouse1.64002292
46P300_19829295_ChIP-Seq_ESCs_Human1.62489949
47FUS_26573619_Chip-Seq_HEK293_Human1.62169576
48RUNX1_27457419_Chip-Seq_LIVER_Mouse1.62024477
49OCT4_18555785_Chip-Seq_ESCs_Mouse1.60611276
50P300_18555785_Chip-Seq_ESCs_Mouse1.59527075
51RNF2_27304074_Chip-Seq_NSC_Mouse1.59493101
52EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.57805769
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.57738832
54SMAD_19615063_ChIP-ChIP_OVARY_Human1.55721406
55VDR_22108803_ChIP-Seq_LS180_Human1.54261915
56NR3C1_21868756_ChIP-Seq_MCF10A_Human1.53883951
57AR_21572438_ChIP-Seq_LNCaP_Human1.53573477
58TAL1_26923725_Chip-Seq_HPCs_Mouse1.51851040
59ZFX_18555785_Chip-Seq_ESCs_Mouse1.50742336
60KLF4_18555785_Chip-Seq_ESCs_Mouse1.48987297
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.48968331
62KLF5_20875108_ChIP-Seq_MESCs_Mouse1.43349544
63ESRRB_18555785_Chip-Seq_ESCs_Mouse1.40835270
64SMAD4_21799915_ChIP-Seq_A2780_Human1.40256242
65NANOG_19829295_ChIP-Seq_ESCs_Human1.39545877
66SOX2_19829295_ChIP-Seq_ESCs_Human1.39545877
67TCF4_22108803_ChIP-Seq_LS180_Human1.39032155
68SMAD1_18555785_Chip-Seq_ESCs_Mouse1.38833844
69CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38531941
70PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.38436136
71RUNX2_22187159_ChIP-Seq_PCA_Human1.36723342
72CTCF_18555785_Chip-Seq_ESCs_Mouse1.33078608
73CRX_20693478_ChIP-Seq_RETINA_Mouse1.32608497
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.32299497
75KAP1_22055183_ChIP-Seq_ESCs_Mouse1.31827064
76MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.31284477
77FLI1_21867929_ChIP-Seq_TH2_Mouse1.30854543
78* SMAD4_21741376_ChIP-Seq_EPCs_Human1.30036043
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29644224
80TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29600946
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.29600946
82OCT4_21477851_ChIP-Seq_ESCs_Mouse1.27167666
83PRDM14_20953172_ChIP-Seq_ESCs_Human1.27109612
84MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.26302228
85TP53_22573176_ChIP-Seq_HFKS_Human1.22862859
86LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.22229706
87REST_21632747_ChIP-Seq_MESCs_Mouse1.20762392
88PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.19655308
89KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.19629237
90CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.19627962
91* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18927305
92AR_25329375_ChIP-Seq_VCAP_Human1.18702595
93IGF1R_20145208_ChIP-Seq_DFB_Human1.18554681
94CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.16076247
95CDX2_22108803_ChIP-Seq_LS180_Human1.15653807
96RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.15305727
97SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.15081583
98ER_23166858_ChIP-Seq_MCF-7_Human1.14657561
99KDM2B_26808549_Chip-Seq_REH_Human1.14107685
100CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13705600
101EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.13496245
102IKZF1_21737484_ChIP-ChIP_HCT116_Human1.13111805
103TCF4_23295773_ChIP-Seq_U87_Human1.12239936
104LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.12019579
105TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.11937151
106GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11705141
107PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.10544906
108SALL1_21062744_ChIP-ChIP_HESCs_Human1.10292366
109TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.09725748
110HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.09203035
111STAT1_17558387_ChIP-Seq_HELA_Human1.08283326
112TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08114521
113HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.07964233
114FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.07857144
115TP63_19390658_ChIP-ChIP_HaCaT_Human1.07641386
116* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.07598405
117* FOXA1_25329375_ChIP-Seq_VCAP_Human1.07598405
118E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.06364447
119EWS_26573619_Chip-Seq_HEK293_Human1.06146240
120NCOR_22424771_ChIP-Seq_293T_Human1.05300133
121SOX2_21211035_ChIP-Seq_LN229_Gbm1.05241773
122CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.04558818
123IRF8_27001747_Chip-Seq_BMDM_Mouse1.02949556
124RXR_22108803_ChIP-Seq_LS180_Human1.02250527
125UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01490831
126TOP2B_26459242_ChIP-Seq_MCF-7_Human1.01467529
127ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.01424090
128MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00824064
129ETV2_25802403_ChIP-Seq_MESCs_Mouse0.99305512
130SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.99267638
131NOTCH1_21737748_ChIP-Seq_TLL_Human0.98976977
132STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.98333871
133FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.97845036
134ARNT_22903824_ChIP-Seq_MCF-7_Human0.97297557
135RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96895315
136EZH2_27304074_Chip-Seq_ESCs_Mouse0.96519581
137SOX9_26525672_Chip-Seq_HEART_Mouse0.96310710
138JUN_21703547_ChIP-Seq_K562_Human0.96162804
139PIAS1_25552417_ChIP-Seq_VCAP_Human0.95268404
140SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93965262
141GF1_26923725_Chip-Seq_HPCs_Mouse0.93332320
142IRF1_19129219_ChIP-ChIP_H3396_Human0.92922490
143SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.92053158
144Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.92040534
145TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91396213
146STAT4_19710469_ChIP-ChIP_TH1__Mouse0.91050727

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization4.28802261
2MP0003787_abnormal_imprinting3.59957688
3MP0002876_abnormal_thyroid_physiology3.45020995
4MP0001188_hyperpigmentation3.13970595
5MP0006292_abnormal_olfactory_placode3.12109228
6MP0001835_abnormal_antigen_presentation3.06858919
7MP0008877_abnormal_DNA_methylation2.95106453
8MP0005645_abnormal_hypothalamus_physiol2.89447787
9MP0003195_calcinosis2.83576472
10MP0000569_abnormal_digit_pigmentation2.74491960
11MP0002102_abnormal_ear_morphology2.56654206
12MP0005646_abnormal_pituitary_gland2.36353484
13MP0005671_abnormal_response_to2.31099939
14MP0002837_dystrophic_cardiac_calcinosis2.30742180
15MP0002638_abnormal_pupillary_reflex2.29742703
16MP0000372_irregular_coat_pigmentation2.20983766
17MP0008058_abnormal_DNA_repair2.17489077
18MP0001485_abnormal_pinna_reflex2.17309877
19MP0002163_abnormal_gland_morphology2.17236947
20MP0005253_abnormal_eye_physiology2.06069932
21MP0003136_yellow_coat_color2.04540537
22MP0009785_altered_susceptibility_to2.02436643
23MP0002148_abnormal_hypersensitivity_rea2.00808777
24MP0008872_abnormal_physiological_respon1.98180775
25MP0010386_abnormal_urinary_bladder1.94662927
26MP0006072_abnormal_retinal_apoptosis1.85049962
27MP0005379_endocrine/exocrine_gland_phen1.82068585
28MP0003698_abnormal_male_reproductive1.79800826
29MP0002272_abnormal_nervous_system1.75974334
30MP0005171_absent_coat_pigmentation1.73464697
31MP0004742_abnormal_vestibular_system1.73310581
32MP0004885_abnormal_endolymph1.71461822
33MP0000566_synostosis1.70680246
34MP0008260_abnormal_autophagy1.69173821
35MP0000015_abnormal_ear_pigmentation1.65528073
36MP0005387_immune_system_phenotype1.65499686
37MP0001790_abnormal_immune_system1.65499686
38MP0002160_abnormal_reproductive_system1.65397647
39MP0003880_abnormal_central_pattern1.64453927
40MP0009697_abnormal_copulation1.62882182
41MP0002234_abnormal_pharynx_morphology1.62830796
42MP0001929_abnormal_gametogenesis1.59293464
43MP0001986_abnormal_taste_sensitivity1.56838519
44MP0002736_abnormal_nociception_after1.55559856
45MP0001529_abnormal_vocalization1.55114182
46MP0001346_abnormal_lacrimal_gland1.54727592
47MP0004043_abnormal_pH_regulation1.54541126
48MP0001853_heart_inflammation1.54291340
49MP0002419_abnormal_innate_immunity1.51540138
50MP0001502_abnormal_circadian_rhythm1.50481285
51MP0004142_abnormal_muscle_tone1.47102360
52MP0005025_abnormal_response_to1.40778773
53MP0002138_abnormal_hepatobiliary_system1.38783384
54MP0005389_reproductive_system_phenotype1.32691591
55MP0008007_abnormal_cellular_replicative1.32097406
56MP0003111_abnormal_nucleus_morphology1.31906191
57MP0004782_abnormal_surfactant_physiolog1.31787882
58MP0005174_abnormal_tail_pigmentation1.30944660
59MP0000685_abnormal_immune_system1.29507233
60MP0001970_abnormal_pain_threshold1.29114565
61MP0010094_abnormal_chromosome_stability1.29052553
62MP0002452_abnormal_antigen_presenting1.28813231
63MP0000427_abnormal_hair_cycle1.26623564
64MP0002210_abnormal_sex_determination1.26488901
65MP0000681_abnormal_thyroid_gland1.26103227
66MP0001501_abnormal_sleep_pattern1.24638658
67MP0003183_abnormal_peptide_metabolism1.24520826
68MP0003121_genomic_imprinting1.24222073
69MP0002938_white_spotting1.23203940
70MP0005000_abnormal_immune_tolerance1.23130483
71MP0009764_decreased_sensitivity_to1.22600020
72MP0009046_muscle_twitch1.21232567
73MP0005386_behavior/neurological_phenoty1.20885936
74MP0004924_abnormal_behavior1.20885936
75MP0004215_abnormal_myocardial_fiber1.20373051
76MP0003950_abnormal_plasma_membrane1.19842742
77MP0002653_abnormal_ependyma_morphology1.19104900
78MP0005377_hearing/vestibular/ear_phenot1.18996184
79MP0003878_abnormal_ear_physiology1.18996184
80MP0002723_abnormal_immune_serum1.18681947
81MP0003879_abnormal_hair_cell1.18363506
82MP0002132_abnormal_respiratory_system1.17461574
83MP0001819_abnormal_immune_cell1.17269311
84MP0002277_abnormal_respiratory_mucosa1.16839398
85MP0001119_abnormal_female_reproductive1.15015269
86MP0008995_early_reproductive_senescence1.14944091
87MP0002420_abnormal_adaptive_immunity1.14658516
88MP0004147_increased_porphyrin_level1.14037339
89MP0002735_abnormal_chemical_nociception1.13886401
90MP0006082_CNS_inflammation1.12921586
91MP0001800_abnormal_humoral_immune1.11222776
92MP0003890_abnormal_embryonic-extraembry1.10299107
93MP0002733_abnormal_thermal_nociception1.09412913
94MP0002396_abnormal_hematopoietic_system1.09355575
95MP0001968_abnormal_touch/_nociception1.08650600
96MP0006276_abnormal_autonomic_nervous1.08627659
97MP0002734_abnormal_mechanical_nocicepti1.08400439
98MP0005310_abnormal_salivary_gland1.06643134
99MP0002229_neurodegeneration1.05774635
100MP0008875_abnormal_xenobiotic_pharmacok1.05729415
101MP0003786_premature_aging1.05470857
102MP0005195_abnormal_posterior_eye1.04717584
103MP0001919_abnormal_reproductive_system1.04692930
104MP0003718_maternal_effect1.03542606
105MP0002751_abnormal_autonomic_nervous1.02917022
106MP0001984_abnormal_olfaction1.02440335
107MP0000383_abnormal_hair_follicle1.01725838
108MP0001486_abnormal_startle_reflex1.00751591
109MP0004145_abnormal_muscle_electrophysio1.00575982
110MP0002928_abnormal_bile_duct1.00498878
111MP0001963_abnormal_hearing_physiology0.99804625
112MP0001764_abnormal_homeostasis0.99664403
113MP0002184_abnormal_innervation0.99143206
114MP0002254_reproductive_system_inflammat0.98687018
115MP0000516_abnormal_urinary_system0.98142882
116MP0005367_renal/urinary_system_phenotyp0.98142882
117MP0004085_abnormal_heartbeat0.97998248
118MP0001440_abnormal_grooming_behavior0.97823220
119MP0003763_abnormal_thymus_physiology0.97612710
120MP0002063_abnormal_learning/memory/cond0.95624585
121MP0008057_abnormal_DNA_replication0.95413069
122MP0005075_abnormal_melanosome_morpholog0.95007402
123MP0005084_abnormal_gallbladder_morpholo0.93939044
124MP0002752_abnormal_somatic_nervous0.93747211
125MP0000230_abnormal_systemic_arterial0.93616513
126MP0003941_abnormal_skin_development0.93527072
127MP0003633_abnormal_nervous_system0.93157913
128MP0009745_abnormal_behavioral_response0.92360790
129MP0001873_stomach_inflammation0.90809032
130MP0002572_abnormal_emotion/affect_behav0.88832789
131MP0001145_abnormal_male_reproductive0.88582982
132MP0005395_other_phenotype0.88579486
133MP0003137_abnormal_impulse_conducting0.86158165
134MP0003252_abnormal_bile_duct0.85575401
135MP0000778_abnormal_nervous_system0.85371995
136MP0000653_abnormal_sex_gland0.85032675
137MP0003119_abnormal_digestive_system0.85014451
138MP0002161_abnormal_fertility/fecundity0.84387019
139MP0002398_abnormal_bone_marrow0.82747985
140MP0000716_abnormal_immune_system0.82046960
141MP0004133_heterotaxia0.82003228
142MP0002067_abnormal_sensory_capabilities0.81806242
143MP0008789_abnormal_olfactory_epithelium0.80715360
144MP0002095_abnormal_skin_pigmentation0.79745547
145MP0002557_abnormal_social/conspecific_i0.79713082
146MP0010329_abnormal_lipoprotein_level0.78879159
147MP0001905_abnormal_dopamine_level0.78411726
148MP0000631_abnormal_neuroendocrine_gland0.77546167
149MP0003122_maternal_imprinting0.77303032
150MP0003635_abnormal_synaptic_transmissio0.75954598
151MP0003646_muscle_fatigue0.75741254
152MP0005551_abnormal_eye_electrophysiolog0.75266116
153MP0005397_hematopoietic_system_phenotyp0.74980013
154MP0001545_abnormal_hematopoietic_system0.74980013
155MP0000026_abnormal_inner_ear0.74430974
156MP0003045_fibrosis0.74347863
157MP0002168_other_aberrant_phenotype0.74107436
158MP0002064_seizures0.73932504
159MP0005647_abnormal_sex_gland0.73799900

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)7.05976085
2Chromsome breakage (HP:0040012)6.41723524
3Dynein arm defect of respiratory motile cilia (HP:0012255)4.88694848
4Absent/shortened dynein arms (HP:0200106)4.88694848
5Congenital stationary night blindness (HP:0007642)4.52105234
6Pancreatic cysts (HP:0001737)4.38553797
7Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.18869377
8Abnormal respiratory motile cilium morphology (HP:0005938)3.73441691
9Abnormal respiratory epithelium morphology (HP:0012253)3.73441691
10Attenuation of retinal blood vessels (HP:0007843)3.73101546
11Aplastic anemia (HP:0001915)3.65249833
12Retrobulbar optic neuritis (HP:0100654)3.39174445
13Optic neuritis (HP:0100653)3.39174445
14Aplasia/Hypoplasia of the uvula (HP:0010293)3.35371311
15Abnormality of the preputium (HP:0100587)3.30590127
16Hyperventilation (HP:0002883)3.30506384
17Abnormal rod and cone electroretinograms (HP:0008323)3.29710932
18Meckel diverticulum (HP:0002245)3.23572731
19Abnormality of chromosome stability (HP:0003220)3.22520193
20Abnormal ciliary motility (HP:0012262)3.21138421
21Gaze-evoked nystagmus (HP:0000640)3.16850657
22Abnormal respiratory motile cilium physiology (HP:0012261)3.15838763
23Abolished electroretinogram (ERG) (HP:0000550)3.12975130
24Abnormality of the ileum (HP:0001549)3.07015467
25Clubbing of toes (HP:0100760)3.05610198
26Increased IgM level (HP:0003496)3.02033507
27Chronic hepatic failure (HP:0100626)2.98937622
28Cystic liver disease (HP:0006706)2.92383697
29Abnormal delayed hypersensitivity skin test (HP:0002963)2.91020961
30Abnormality of macular pigmentation (HP:0008002)2.89353469
31Bony spicule pigmentary retinopathy (HP:0007737)2.87944649
32Myositis (HP:0100614)2.87541397
33Duplicated collecting system (HP:0000081)2.82547890
34Progressive cerebellar ataxia (HP:0002073)2.80025131
35Inability to walk (HP:0002540)2.75090848
36Abnormality of the renal collecting system (HP:0004742)2.69122772
37Intestinal atresia (HP:0011100)2.66322220
38Febrile seizures (HP:0002373)2.65094404
39Orchitis (HP:0100796)2.64904213
40Aplasia/Hypoplasia of the tibia (HP:0005772)2.62030161
41Genetic anticipation (HP:0003743)2.58954837
42Central scotoma (HP:0000603)2.58782841
43Septo-optic dysplasia (HP:0100842)2.57136718
44Pendular nystagmus (HP:0012043)2.55737664
45Progressive inability to walk (HP:0002505)2.55528162
46Focal seizures (HP:0007359)2.54479980
47Increased corneal curvature (HP:0100692)2.53425199
48Keratoconus (HP:0000563)2.53425199
49Nephroblastoma (Wilms tumor) (HP:0002667)2.52320362
50Absent rod-and cone-mediated responses on ERG (HP:0007688)2.51549513
51Epileptic encephalopathy (HP:0200134)2.51385487
52Abnormal hair whorl (HP:0010721)2.43682941
53Severe visual impairment (HP:0001141)2.42005839
54Type 2 muscle fiber atrophy (HP:0003554)2.40228826
55Thyroid-stimulating hormone excess (HP:0002925)2.40219842
56Small intestinal stenosis (HP:0012848)2.39213954
57Duodenal stenosis (HP:0100867)2.39213954
58Type II lissencephaly (HP:0007260)2.39180995
59Tubular atrophy (HP:0000092)2.38720715
60Polydipsia (HP:0001959)2.37403516
61Abnormal drinking behavior (HP:0030082)2.37403516
62Aplasia/Hypoplasia involving the sinuses (HP:0009120)2.34522036
63Congenital hepatic fibrosis (HP:0002612)2.34376106
64Absent speech (HP:0001344)2.32653651
65Constricted visual fields (HP:0001133)2.32439874
66Encephalitis (HP:0002383)2.32282965
67Embryonal renal neoplasm (HP:0011794)2.31088758
68Rhinitis (HP:0012384)2.25591391
69Protruding tongue (HP:0010808)2.25487170
70Sclerocornea (HP:0000647)2.25051593
71Hypoplasia of the fovea (HP:0007750)2.23597901
72Aplasia/Hypoplasia of the fovea (HP:0008060)2.23597901
73Double outlet right ventricle (HP:0001719)2.20826431
74Congenital malformation of the right heart (HP:0011723)2.20826431
75Recurrent sinusitis (HP:0011108)2.17236042
76Gait imbalance (HP:0002141)2.14953433
77Aplasia/Hypoplasia of the tongue (HP:0010295)2.14775937
78Ectopic kidney (HP:0000086)2.12229246
79True hermaphroditism (HP:0010459)2.11915899
80Tubulointerstitial abnormality (HP:0001969)2.11063696
81Congenital primary aphakia (HP:0007707)2.10664463
82Broad-based gait (HP:0002136)2.10437376
83Type I transferrin isoform profile (HP:0003642)2.10234009
84Stomach cancer (HP:0012126)2.09872326
85Focal motor seizures (HP:0011153)2.09576166
86Reduced antithrombin III activity (HP:0001976)2.09363008
87Decreased electroretinogram (ERG) amplitude (HP:0000654)2.08953188
88Abnormal spermatogenesis (HP:0008669)2.07882425
89Recurrent cutaneous fungal infections (HP:0011370)2.07770636
90Chronic mucocutaneous candidiasis (HP:0002728)2.07770636
91Recurrent abscess formation (HP:0002722)2.06786981
92Abnormality of the carotid arteries (HP:0005344)2.06393456
93Polyuria (HP:0000103)2.05215525
94Congenital sensorineural hearing impairment (HP:0008527)2.05153940
95Renal cortical cysts (HP:0000803)2.04413010
96Generalized hypopigmentation of hair (HP:0011358)2.04370647
97Abnormality of DNA repair (HP:0003254)2.04079083
98Hemiparesis (HP:0001269)2.03760061
99Genital tract atresia (HP:0001827)2.02033313
100Optic nerve hypoplasia (HP:0000609)2.01709782
101Recurrent pneumonia (HP:0006532)2.00833518
102Dialeptic seizures (HP:0011146)2.00722791
103Tubulointerstitial nephritis (HP:0001970)2.00622996
104Keratoconjunctivitis (HP:0001096)1.99958985
105Scotoma (HP:0000575)1.99477533
106Postaxial foot polydactyly (HP:0001830)1.99451106
107Keratoconjunctivitis sicca (HP:0001097)1.98166289
108Bone marrow hypocellularity (HP:0005528)1.96915723
109Bile duct proliferation (HP:0001408)1.96603814
110Abnormal biliary tract physiology (HP:0012439)1.96603814
111Anencephaly (HP:0002323)1.96541615
112Myelodysplasia (HP:0002863)1.96412883
113Oligohydramnios (HP:0001562)1.96017427
114Fibular hypoplasia (HP:0003038)1.95899123
115Clumsiness (HP:0002312)1.94037104
116Chorioretinal atrophy (HP:0000533)1.93466616
117Pancreatic fibrosis (HP:0100732)1.90694304
118Furrowed tongue (HP:0000221)1.90222212
119Vaginal atresia (HP:0000148)1.88077403
120Petechiae (HP:0000967)1.87321623
121Panhypogammaglobulinemia (HP:0003139)1.87063674
122Hypergonadotropic hypogonadism (HP:0000815)1.86424390
123Amelogenesis imperfecta (HP:0000705)1.85878699
124Small hand (HP:0200055)1.85798915
125Nephronophthisis (HP:0000090)1.85109606
126Hypothermia (HP:0002045)1.85005302
127Nephrogenic diabetes insipidus (HP:0009806)1.84768689
128Large for gestational age (HP:0001520)1.83236211
129Elevated erythrocyte sedimentation rate (HP:0003565)1.83221946
130Ketoacidosis (HP:0001993)1.83178086
131Abnormality of T cell physiology (HP:0011840)1.82679798
132Abnormality of the fovea (HP:0000493)1.82418703
133Cerebellar dysplasia (HP:0007033)1.81358028
134Decreased circulating renin level (HP:0003351)1.81213399
135Methylmalonic acidemia (HP:0002912)1.80643687
136Medial flaring of the eyebrow (HP:0010747)1.80577185
137Fibular aplasia (HP:0002990)1.80568901
138Prostate neoplasm (HP:0100787)1.80433807
139Embryonal neoplasm (HP:0002898)1.80318042
140Abnormality of the duodenum (HP:0002246)1.79914601
141Tubulointerstitial fibrosis (HP:0005576)1.78844118
142Drooling (HP:0002307)1.78304399
143Retinitis pigmentosa (HP:0000510)1.78193508
144Preaxial hand polydactyly (HP:0001177)1.77951977
145Decreased central vision (HP:0007663)1.77671794
146Anomalous pulmonary venous return (HP:0010772)1.76764187
147Methylmalonic aciduria (HP:0012120)1.76514934
148Molar tooth sign on MRI (HP:0002419)1.74968812
149Abnormality of midbrain morphology (HP:0002418)1.74968812
150Pancytopenia (HP:0001876)1.74732823
151Male pseudohermaphroditism (HP:0000037)1.74373905
152Astigmatism (HP:0000483)1.73224793
153Albinism (HP:0001022)1.73126717
154Abnormality of alanine metabolism (HP:0010916)1.73027666
155Hyperalaninemia (HP:0003348)1.73027666
156Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.73027666
157Abnormality of B cell number (HP:0010975)1.73008029
158B lymphocytopenia (HP:0010976)1.73008029
159Glomerulopathy (HP:0100820)1.72073075
160Abnormality of the renal medulla (HP:0100957)1.71953382
161Basal ganglia calcification (HP:0002135)1.70887908
162Fair hair (HP:0002286)1.70822322
163IgM deficiency (HP:0002850)1.70427215
164Abnormality of the renal cortex (HP:0011035)1.70158550
165Ketosis (HP:0001946)1.69951910
166Recurrent lower respiratory tract infections (HP:0002783)1.69781393
167Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69199558
168Muscle fiber atrophy (HP:0100295)1.67418503
169IgG deficiency (HP:0004315)1.67174100
170Bronchiectasis (HP:0002110)1.66206552
171Short thumb (HP:0009778)1.65462878

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK7.73164421
2ZAK4.14846650
3TNIK3.67872861
4CASK3.58248113
5IRAK33.45627118
6MAP4K23.15636295
7IRAK42.90639994
8ACVR1B2.89454081
9MAP3K142.73775108
10TXK2.30181569
11SIK32.11560282
12PINK12.07159152
13INSRR2.00904030
14MAP2K71.96312132
15TAOK31.89611628
16CDK31.87153601
17PLK41.81433263
18STK38L1.80478498
19IRAK11.80060429
20NLK1.78465263
21MAP3K121.66661102
22BMPR21.61904265
23PRPF4B1.61862441
24OXSR11.57694330
25YES11.55706469
26ERBB31.52805605
27NEK61.52268986
28PIK3CG1.47024718
29PDK21.46612156
30AKT31.39576183
31BLK1.38929121
32MAPK131.35649766
33IRAK21.33682581
34MAP3K41.31478958
35FER1.31368395
36STK161.30527571
37EIF2AK21.30369380
38PNCK1.29973219
39MKNK21.28449156
40PDK41.25144095
41PDK31.25144095
42MUSK1.25054533
43BMPR1B1.22824422
44STK391.21712015
45ADRBK21.19487069
46SGK21.18264207
47GRK11.17721246
48PAK31.16548997
49TYK21.13855995
50TTK1.12900438
51TRIM281.09905464
52PTK2B1.06938813
53DAPK21.06867463
54TGFBR11.06239373
55MAPK71.05129016
56ADRBK11.05095769
57TEC1.04837313
58WNK31.04339823
59JAK31.03654980
60IKBKE1.02511392
61SRPK11.00922783
62MKNK11.00248891
63NTRK30.98265818
64CCNB10.97188153
65IKBKB0.96203057
66TLK10.95364125
67KIT0.92872851
68WNK40.91164610
69ATR0.90630184
70TESK10.88979238
71BCR0.87915945
72EIF2AK30.87906189
73CSNK1G20.83931054
74STK30.83308153
75CSNK1G10.81305627
76EPHA30.80994435
77NUAK10.80403362
78TNK20.78571524
79PRKD30.78332512
80BTK0.77581072
81PLK20.75672491
82TBK10.74179753
83MARK10.71453868
84CSNK1A1L0.71318354
85STK380.70855417
86LATS10.70340470
87CSNK1G30.68554976
88LYN0.68521701
89SGK4940.67855998
90SGK2230.67855998
91EPHA40.66502170
92MAPK150.64525851
93SYK0.64206131
94CHEK20.63319037
95BRAF0.63046760
96TIE10.62731356
97NTRK20.61800431
98CDC70.60143735
99CHUK0.58947941
100BRD40.56406140
101VRK10.54700563
102FES0.53190438
103RIPK40.51835052
104PLK30.51309573
105DYRK20.50145636
106PRKCE0.49699902
107PRKCG0.48827820
108WEE10.48626470
109HCK0.48407854
110MAPKAPK30.48118970
111CDK80.47430854
112CLK10.47165077
113PRKACA0.46410008
114JAK10.45321103
115FGFR20.45158239
116PRKAA20.45001070
117CAMK10.44870228
118PIK3CA0.44630497
119ITK0.43814178
120PKN10.43735644
121CSNK1A10.43253174
122GRK70.40853226
123PRKCD0.39797112
124PIM20.39731407
125ZAP700.39656198
126CDK190.39633940
127TSSK60.39388792
128SGK30.39114077
129RPS6KB10.38453988
130MAP3K130.38317737
131PRKCQ0.38239449
132BRSK20.37441449
133LCK0.37152397
134PRKG10.35748238
135CSNK1D0.35674295
136OBSCN0.35447950
137NME10.35088869
138PBK0.34871836
139CAMKK20.34527670
140SIK20.33893703
141PHKG20.33488195
142PHKG10.33488195
143IGF1R0.33098216
144MYLK0.32804721
145GRK50.32576181
146CAMK2D0.32426861
147MAP2K60.31718821
148CAMK2A0.31686737
149PRKCZ0.31419536
150PRKCA0.31052577
151MAP3K60.30963266
152PIM10.30434338
153MAPKAPK50.29530211
154BCKDK0.27464408
155PRKCB0.27031617

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034602.98565847
2Butanoate metabolism_Homo sapiens_hsa006502.97227746
3Allograft rejection_Homo sapiens_hsa053302.95181654
4Intestinal immune network for IgA production_Homo sapiens_hsa046722.79400758
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.74853227
6Autoimmune thyroid disease_Homo sapiens_hsa053202.69883541
7Nicotine addiction_Homo sapiens_hsa050332.51842745
8Primary immunodeficiency_Homo sapiens_hsa053402.17580537
9Tryptophan metabolism_Homo sapiens_hsa003802.15670568
10Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.12505164
11Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006032.02622319
12Selenocompound metabolism_Homo sapiens_hsa004501.98067897
13Nitrogen metabolism_Homo sapiens_hsa009101.94859663
14Graft-versus-host disease_Homo sapiens_hsa053321.89459288
15Other glycan degradation_Homo sapiens_hsa005111.83823939
16NF-kappa B signaling pathway_Homo sapiens_hsa040641.76811773
17Rheumatoid arthritis_Homo sapiens_hsa053231.72227566
18Asthma_Homo sapiens_hsa053101.69813898
19Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.68586190
20Maturity onset diabetes of the young_Homo sapiens_hsa049501.68528245
21Type I diabetes mellitus_Homo sapiens_hsa049401.68040494
22Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.67453632
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.62832087
24Vitamin B6 metabolism_Homo sapiens_hsa007501.61207996
25Homologous recombination_Homo sapiens_hsa034401.60349328
26Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.59932835
27Sphingolipid metabolism_Homo sapiens_hsa006001.58462807
28Measles_Homo sapiens_hsa051621.58390749
29Proteasome_Homo sapiens_hsa030501.56181912
30ABC transporters_Homo sapiens_hsa020101.55861739
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54703078
32SNARE interactions in vesicular transport_Homo sapiens_hsa041301.54255444
33Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.49472754
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.49177177
35Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.42495701
36Propanoate metabolism_Homo sapiens_hsa006401.41523179
37Mismatch repair_Homo sapiens_hsa034301.39747125
38Collecting duct acid secretion_Homo sapiens_hsa049661.39636737
39Base excision repair_Homo sapiens_hsa034101.38237188
40Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.37588051
41Retinol metabolism_Homo sapiens_hsa008301.36254418
42Basal transcription factors_Homo sapiens_hsa030221.36226982
43Non-homologous end-joining_Homo sapiens_hsa034501.31416901
44Toll-like receptor signaling pathway_Homo sapiens_hsa046201.29915687
45Primary bile acid biosynthesis_Homo sapiens_hsa001201.29631294
46Caffeine metabolism_Homo sapiens_hsa002321.28029214
47Chemical carcinogenesis_Homo sapiens_hsa052041.25581839
48RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.24803551
49Taste transduction_Homo sapiens_hsa047421.21662554
50beta-Alanine metabolism_Homo sapiens_hsa004101.20748467
51NOD-like receptor signaling pathway_Homo sapiens_hsa046211.20134249
52Olfactory transduction_Homo sapiens_hsa047401.18725021
53Arachidonic acid metabolism_Homo sapiens_hsa005901.17583131
54DNA replication_Homo sapiens_hsa030301.14599006
55Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10103836
56Leishmaniasis_Homo sapiens_hsa051401.08094630
57Morphine addiction_Homo sapiens_hsa050321.07836303
58Histidine metabolism_Homo sapiens_hsa003401.07420212
59Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.06768493
60Glycosaminoglycan degradation_Homo sapiens_hsa005311.05942743
61Herpes simplex infection_Homo sapiens_hsa051681.03917556
62Glycerolipid metabolism_Homo sapiens_hsa005611.03462381
63Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.02668918
64Dorso-ventral axis formation_Homo sapiens_hsa043200.99105607
65Synaptic vesicle cycle_Homo sapiens_hsa047210.98900971
66Malaria_Homo sapiens_hsa051440.94640149
67Circadian entrainment_Homo sapiens_hsa047130.93411310
68Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.92703713
69Purine metabolism_Homo sapiens_hsa002300.91253931
70Phagosome_Homo sapiens_hsa041450.91007317
71Influenza A_Homo sapiens_hsa051640.90997469
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.90057433
73Calcium signaling pathway_Homo sapiens_hsa040200.87696753
74Phototransduction_Homo sapiens_hsa047440.87491026
75Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.85676997
76African trypanosomiasis_Homo sapiens_hsa051430.85135415
77RNA degradation_Homo sapiens_hsa030180.84751916
78Phosphatidylinositol signaling system_Homo sapiens_hsa040700.83864529
79Legionellosis_Homo sapiens_hsa051340.83427456
80Fatty acid biosynthesis_Homo sapiens_hsa000610.82794045
81Regulation of autophagy_Homo sapiens_hsa041400.82653487
82p53 signaling pathway_Homo sapiens_hsa041150.82551948
83Peroxisome_Homo sapiens_hsa041460.82274020
84Fat digestion and absorption_Homo sapiens_hsa049750.81576165
85Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.79850557
86Glutamatergic synapse_Homo sapiens_hsa047240.78281742
87One carbon pool by folate_Homo sapiens_hsa006700.77823242
88Pyrimidine metabolism_Homo sapiens_hsa002400.77444722
89Inositol phosphate metabolism_Homo sapiens_hsa005620.76567476
90Vascular smooth muscle contraction_Homo sapiens_hsa042700.75925848
91Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.75190365
92Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.72300554
93Renin secretion_Homo sapiens_hsa049240.72291874
94Jak-STAT signaling pathway_Homo sapiens_hsa046300.71580473
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.70824862
96Antigen processing and presentation_Homo sapiens_hsa046120.69636830
97Tuberculosis_Homo sapiens_hsa051520.69405323
98Circadian rhythm_Homo sapiens_hsa047100.68461140
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67447504
100Ether lipid metabolism_Homo sapiens_hsa005650.66940338
101Dopaminergic synapse_Homo sapiens_hsa047280.65555333
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.65354549
103Hematopoietic cell lineage_Homo sapiens_hsa046400.65308338
104Fatty acid degradation_Homo sapiens_hsa000710.64513950
105Serotonergic synapse_Homo sapiens_hsa047260.64080821
106Shigellosis_Homo sapiens_hsa051310.63242464
107cAMP signaling pathway_Homo sapiens_hsa040240.62658530
108Cell cycle_Homo sapiens_hsa041100.62342713
109TNF signaling pathway_Homo sapiens_hsa046680.61350830
110Chemokine signaling pathway_Homo sapiens_hsa040620.60446096
111Cholinergic synapse_Homo sapiens_hsa047250.60025286
112Protein export_Homo sapiens_hsa030600.59850468
113Gastric acid secretion_Homo sapiens_hsa049710.59514979
114Nucleotide excision repair_Homo sapiens_hsa034200.58136546
115Insulin secretion_Homo sapiens_hsa049110.58063635
116Lysine degradation_Homo sapiens_hsa003100.55778323
117Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.54618660
118Long-term depression_Homo sapiens_hsa047300.54483180
119Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.54476510
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.54035954
121Steroid hormone biosynthesis_Homo sapiens_hsa001400.52334715
122Vitamin digestion and absorption_Homo sapiens_hsa049770.52308075
123RNA polymerase_Homo sapiens_hsa030200.51045258
124Sulfur metabolism_Homo sapiens_hsa009200.50531536
125Metabolic pathways_Homo sapiens_hsa011000.50278775
126Pertussis_Homo sapiens_hsa051330.49289816
127Fatty acid metabolism_Homo sapiens_hsa012120.49094539
128Amphetamine addiction_Homo sapiens_hsa050310.48668027
129Osteoclast differentiation_Homo sapiens_hsa043800.48168354
130Aldosterone synthesis and secretion_Homo sapiens_hsa049250.47642846
131Steroid biosynthesis_Homo sapiens_hsa001000.47429618
132Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.46956116
133Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45613626
134Salmonella infection_Homo sapiens_hsa051320.43530415
135Oxytocin signaling pathway_Homo sapiens_hsa049210.43242398
136Pancreatic secretion_Homo sapiens_hsa049720.42888769
137Epstein-Barr virus infection_Homo sapiens_hsa051690.42258697
138GABAergic synapse_Homo sapiens_hsa047270.42107265
139Arginine and proline metabolism_Homo sapiens_hsa003300.41206065
140Glutathione metabolism_Homo sapiens_hsa004800.40865430
141Cysteine and methionine metabolism_Homo sapiens_hsa002700.40651492
142Vibrio cholerae infection_Homo sapiens_hsa051100.39225460
143Linoleic acid metabolism_Homo sapiens_hsa005910.38488761
144Transcriptional misregulation in cancer_Homo sapiens_hsa052020.38374188
145Salivary secretion_Homo sapiens_hsa049700.36891423
146alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.36662292
147Ovarian steroidogenesis_Homo sapiens_hsa049130.36099573
148Drug metabolism - other enzymes_Homo sapiens_hsa009830.35990207
149Oxidative phosphorylation_Homo sapiens_hsa001900.33870953
150Lysosome_Homo sapiens_hsa041420.32922025
151Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.32791075
152Huntingtons disease_Homo sapiens_hsa050160.27048770
153cGMP-PKG signaling pathway_Homo sapiens_hsa040220.26679739

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