RIBC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sperm-egg recognition (GO:0035036)9.86019889
2motile cilium assembly (GO:0044458)9.50933174
3multicellular organism reproduction (GO:0032504)9.44158714
4cilium movement (GO:0003341)9.19867777
5binding of sperm to zona pellucida (GO:0007339)9.19184211
6piRNA metabolic process (GO:0034587)9.16989205
7plasma membrane fusion (GO:0045026)8.90921333
8DNA synthesis involved in DNA repair (GO:0000731)8.77145801
9cell-cell recognition (GO:0009988)8.77005378
10spermatid development (GO:0007286)8.70826664
11epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.27327164
12reproduction (GO:0000003)8.06669170
13male meiosis (GO:0007140)7.93140653
14regulation of cilium movement (GO:0003352)7.72965141
15synaptonemal complex organization (GO:0070193)7.64417127
16synaptonemal complex assembly (GO:0007130)7.23530720
17single fertilization (GO:0007338)6.49189632
18negative regulation of inclusion body assembly (GO:0090084)6.37591924
19ventricular system development (GO:0021591)6.08175968
20sperm capacitation (GO:0048240)5.95286743
21DNA methylation involved in gamete generation (GO:0043046)5.87849979
22spermatogenesis (GO:0007283)5.86589022
23male gamete generation (GO:0048232)5.84392783
24fertilization (GO:0009566)5.73972963
25gamete generation (GO:0007276)5.38361261
26spermatid nucleus differentiation (GO:0007289)5.33100170
27sister chromatid cohesion (GO:0007062)5.25007538
28male meiosis I (GO:0007141)5.21732740
29left/right pattern formation (GO:0060972)5.10677085
30chromosome organization involved in meiosis (GO:0070192)5.04906058
31microtubule depolymerization (GO:0007019)4.98249814
32germ cell development (GO:0007281)4.97543033
33regulation of inclusion body assembly (GO:0090083)4.94773791
34cellular process involved in reproduction in multicellular organism (GO:0022412)4.90924047
35microtubule severing (GO:0051013)4.87977580
36organic cation transport (GO:0015695)4.79969634
37reciprocal meiotic recombination (GO:0007131)4.77589430
38reciprocal DNA recombination (GO:0035825)4.77589430
39regulation of microtubule-based movement (GO:0060632)4.74533355
40meiotic nuclear division (GO:0007126)4.73803017
41resolution of meiotic recombination intermediates (GO:0000712)4.70411413
42calcium ion-dependent exocytosis (GO:0017156)4.64240029
43cell recognition (GO:0008037)4.61201541
44DNA strand elongation involved in DNA replication (GO:0006271)4.54536713
45meiotic chromosome segregation (GO:0045132)4.48258595
46DNA strand elongation (GO:0022616)4.37902916
47protein polyglutamylation (GO:0018095)4.30809646
48intraciliary transport (GO:0042073)4.30387040
49DNA ligation (GO:0006266)4.24434033
50telomere maintenance via semi-conservative replication (GO:0032201)4.24170300
51multicellular organismal reproductive process (GO:0048609)4.17732682
52meiosis I (GO:0007127)4.17032042
53pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.16869657
54meiotic cell cycle (GO:0051321)4.16635895
55axoneme assembly (GO:0035082)4.11651569
56seminiferous tubule development (GO:0072520)4.08273319
57single strand break repair (GO:0000012)4.01122092
58histone exchange (GO:0043486)3.99909530
59protein localization to cilium (GO:0061512)3.99249629
60DNA biosynthetic process (GO:0071897)3.95373623
61glycerol ether metabolic process (GO:0006662)3.91305673
62regulation of DNA endoreduplication (GO:0032875)3.86658631
63cilium morphogenesis (GO:0060271)3.83923542
64chromosome condensation (GO:0030261)3.83449242
65CENP-A containing nucleosome assembly (GO:0034080)3.77814224
66cilium organization (GO:0044782)3.74483880
67DNA replication initiation (GO:0006270)3.73779941
68DNA packaging (GO:0006323)3.70861369
69DNA replication-dependent nucleosome assembly (GO:0006335)3.70124474
70DNA replication-dependent nucleosome organization (GO:0034723)3.70124474
71chromatin remodeling at centromere (GO:0031055)3.69280804
72proteasome assembly (GO:0043248)3.64912975
73establishment of integrated proviral latency (GO:0075713)3.64819840
74histone H2A acetylation (GO:0043968)3.64057698
75cilium assembly (GO:0042384)3.60934266
76genitalia morphogenesis (GO:0035112)3.60683959
77telomere maintenance via recombination (GO:0000722)3.60392141
78ether metabolic process (GO:0018904)3.60264149
79pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.52049190
80DNA unwinding involved in DNA replication (GO:0006268)3.50731423
81nucleotide-excision repair, DNA gap filling (GO:0006297)3.48647514
82pyrimidine nucleotide catabolic process (GO:0006244)3.45304800
83multicellular organismal development (GO:0007275)3.42492375
84base-excision repair, AP site formation (GO:0006285)3.39639847
85centriole assembly (GO:0098534)3.35497312
86mitotic recombination (GO:0006312)3.34499450
87cellular component assembly involved in morphogenesis (GO:0010927)3.33493925
88nucleoside diphosphate phosphorylation (GO:0006165)3.31192717
89microtubule-based movement (GO:0007018)3.30688523
90GTP biosynthetic process (GO:0006183)3.30483683
91chromosome organization (GO:0051276)3.29393019
92negative regulation of organelle assembly (GO:1902116)3.26926408
93regulation of centriole replication (GO:0046599)3.25813249
94sexual reproduction (GO:0019953)3.25455765
95chaperone-mediated protein complex assembly (GO:0051131)3.23047361
96mitotic chromosome condensation (GO:0007076)3.22794122
97regulation of meiosis I (GO:0060631)3.20005688
98left/right axis specification (GO:0070986)3.17420301
99synapsis (GO:0007129)3.14672475
100lung epithelium development (GO:0060428)3.11745480
101gene silencing by RNA (GO:0031047)3.11082273
102centriole replication (GO:0007099)3.10866887
103DNA replication-independent nucleosome organization (GO:0034724)3.10706586
104DNA replication-independent nucleosome assembly (GO:0006336)3.10706586
105mismatch repair (GO:0006298)3.06997732
106regulation of transcription from RNA polymerase I promoter (GO:0006356)3.05791822
107protein localization to chromosome (GO:0034502)3.05466335
108microtubule bundle formation (GO:0001578)3.02709969
109diterpenoid biosynthetic process (GO:0016102)3.02629715
110deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.02397899
111establishment of viral latency (GO:0019043)2.95957443
112meiotic cell cycle process (GO:1903046)2.94111169
113protein K11-linked deubiquitination (GO:0035871)2.93180100
114UTP biosynthetic process (GO:0006228)2.91153765
115DNA catabolic process, exonucleolytic (GO:0000738)2.89247394
116deoxyribonucleotide catabolic process (GO:0009264)2.87769351
117microtubule polymerization or depolymerization (GO:0031109)2.87007300
118histone H3-K9 demethylation (GO:0033169)2.86880625
119DNA replication checkpoint (GO:0000076)2.84819090
120female gamete generation (GO:0007292)2.82474318
121base-excision repair (GO:0006284)2.82196861
122regulation of meiotic cell cycle (GO:0051445)2.78197629
123protein refolding (GO:0042026)2.78157091
124nucleus organization (GO:0006997)2.77794763
125deoxyribose phosphate catabolic process (GO:0046386)2.77603853
126amino-acid betaine transport (GO:0015838)2.75021914
127carnitine transport (GO:0015879)2.75021914
128glycolytic process (GO:0006096)2.73507712
129telomere maintenance via telomere lengthening (GO:0010833)2.73229134
130nuclear division (GO:0000280)2.70311970
131UTP metabolic process (GO:0046051)2.69806863
132carnitine transmembrane transport (GO:1902603)2.69192433
133lactate metabolic process (GO:0006089)2.68972648
134regulation of histone H3-K9 methylation (GO:0051570)2.66483473
135regulation of double-strand break repair via homologous recombination (GO:0010569)2.65515193
136regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.61716863
137ATP-dependent chromatin remodeling (GO:0043044)2.60270256
138peptidyl-glutamic acid modification (GO:0018200)2.59895841
139nonmotile primary cilium assembly (GO:0035058)2.57726153
140monoubiquitinated protein deubiquitination (GO:0035520)2.56157405
141hyperosmotic salinity response (GO:0042538)2.55457489
142mitotic sister chromatid cohesion (GO:0007064)2.53528612
143mitotic spindle assembly checkpoint (GO:0007094)2.51950026
144regulation of spindle checkpoint (GO:0090231)2.49495458
145alditol metabolic process (GO:0019400)2.46726578
146gene silencing (GO:0016458)2.45363757
147response to pheromone (GO:0019236)2.43459032
148polyol catabolic process (GO:0046174)2.38365919
149cilium or flagellum-dependent cell motility (GO:0001539)12.2870584
150sperm motility (GO:0030317)12.0318136
151fusion of sperm to egg plasma membrane (GO:0007342)11.7113993
152axonemal dynein complex assembly (GO:0070286)10.8382315
153epithelial cilium movement (GO:0003351)10.2537659
154cell wall macromolecule catabolic process (GO:0016998)10.1476625
155cell wall macromolecule metabolic process (GO:0044036)10.1476625
156acrosome assembly (GO:0001675)10.1436787
157acrosome reaction (GO:0007340)10.1068164

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.34553901
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse8.92614316
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat7.28729035
4EZH2_22144423_ChIP-Seq_EOC_Human6.29151007
5E2F4_17652178_ChIP-ChIP_JURKAT_Human4.06993338
6TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.58786258
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.42019814
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.84724498
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.78869013
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.74624718
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.71981314
12BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.66921304
13E2F1_21310950_ChIP-Seq_MCF-7_Human2.62737872
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.53395862
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.49340971
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.40581860
17FLI1_27457419_Chip-Seq_LIVER_Mouse2.37625031
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.36014085
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.29924997
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.25277024
21CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.24997019
22GATA1_26923725_Chip-Seq_HPCs_Mouse2.24210511
23MYC_18358816_ChIP-ChIP_MESCs_Mouse2.21471851
24PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.19950183
25DCP1A_22483619_ChIP-Seq_HELA_Human2.14945318
26VDR_22108803_ChIP-Seq_LS180_Human2.14013541
27EST1_17652178_ChIP-ChIP_JURKAT_Human2.10881667
28ZNF274_21170338_ChIP-Seq_K562_Hela2.10606175
29CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.07646935
30GABP_19822575_ChIP-Seq_HepG2_Human2.02570218
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.96166198
32EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.95394274
33E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.91518825
34HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.83904769
35ETS1_20019798_ChIP-Seq_JURKAT_Human1.82531898
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.82213657
37EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.81159776
38CBX2_27304074_Chip-Seq_ESCs_Mouse1.80994286
39SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.79828395
40* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.78406266
41MYC_19030024_ChIP-ChIP_MESCs_Mouse1.77811389
42STAT6_21828071_ChIP-Seq_BEAS2B_Human1.77679730
43VDR_23849224_ChIP-Seq_CD4+_Human1.77164023
44KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.76783391
45AR_21909140_ChIP-Seq_LNCAP_Human1.76769477
46TTF2_22483619_ChIP-Seq_HELA_Human1.72886916
47FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.72076168
48ELF1_17652178_ChIP-ChIP_JURKAT_Human1.69026201
49MYCN_18555785_ChIP-Seq_MESCs_Mouse1.68213745
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.67333675
51ZFX_18555785_ChIP-Seq_MESCs_Mouse1.64203380
52TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.63166290
53SRF_21415370_ChIP-Seq_HL-1_Mouse1.57297378
54RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.55987400
55MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.55731614
56PADI4_21655091_ChIP-ChIP_MCF-7_Human1.54167730
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.53821870
58XRN2_22483619_ChIP-Seq_HELA_Human1.52286055
59CTBP2_25329375_ChIP-Seq_LNCAP_Human1.52259809
60TAF15_26573619_Chip-Seq_HEK293_Human1.51430854
61NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.51187862
62CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.51079908
63REST_21632747_ChIP-Seq_MESCs_Mouse1.50228578
64PCGF2_27294783_Chip-Seq_NPCs_Mouse1.50159911
65ELK4_26923725_Chip-Seq_MESODERM_Mouse1.49053593
66FOXP3_21729870_ChIP-Seq_TREG_Human1.47181475
67E2F1_18555785_ChIP-Seq_MESCs_Mouse1.45135760
68MYC_18940864_ChIP-ChIP_HL60_Human1.44694314
69POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.43343322
70GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43135647
71TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.43114388
72E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.42785149
73TAL1_26923725_Chip-Seq_HPCs_Mouse1.42771327
74STAT1_17558387_ChIP-Seq_HELA_Human1.41270099
75HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.41159240
76SALL1_21062744_ChIP-ChIP_HESCs_Human1.39988143
77NFE2_27457419_Chip-Seq_LIVER_Mouse1.37210965
78RNF2_27304074_Chip-Seq_NSC_Mouse1.36434490
79TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.36170834
80GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.35026527
81KDM2B_26808549_Chip-Seq_REH_Human1.34421008
82KDM5A_27292631_Chip-Seq_BREAST_Human1.34050942
83SUZ12_27294783_Chip-Seq_NPCs_Mouse1.31841899
84MYC_19079543_ChIP-ChIP_MESCs_Mouse1.30597437
85DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.28660590
86WDR5_24793694_ChIP-Seq_LNCAP_Human1.28459427
87YY1_22570637_ChIP-Seq_MALME-3M_Human1.26925512
88SOX2_22085726_ChIP-Seq_NPCs_Mouse1.26274786
89MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25365921
90FLI1_21867929_ChIP-Seq_TH2_Mouse1.24942765
91POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.24762431
92TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24762431
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23908089
94IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.23699121
95CBP_20019798_ChIP-Seq_JUKART_Human1.23699121
96FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22718054
97* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.21371695
98MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.20890982
99NANOG_18555785_Chip-Seq_ESCs_Mouse1.20032891
100NELFA_20434984_ChIP-Seq_ESCs_Mouse1.19922714
101PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.17618920
102* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.17441340
103YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.17284725
104PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.16899522
105ELF1_20517297_ChIP-Seq_JURKAT_Human1.16551241
106PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.15473316
107TCFCP2L1_18555785_ChIP-Seq_MESCs_Mouse1.15451151
108THAP11_20581084_ChIP-Seq_MESCs_Mouse1.15191739
109RUNX1_26923725_Chip-Seq_HPCs_Mouse1.14890162
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.14034344
111KAP1_22055183_ChIP-Seq_ESCs_Mouse1.13804623
112GATA3_21867929_ChIP-Seq_CD8_Mouse1.13741747
113ESR1_15608294_ChIP-ChIP_MCF-7_Human1.12569198
114P53_22387025_ChIP-Seq_ESCs_Mouse1.10693509
115NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09389948
116GATA3_21867929_ChIP-Seq_TH1_Mouse1.06621600
117CRX_20693478_ChIP-Seq_RETINA_Mouse1.06096309
118CMYC_18555785_Chip-Seq_ESCs_Mouse1.05601590
119LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.05412495
120CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04913119
121E2F1_17053090_ChIP-ChIP_MCF-7_Human1.04147719
122SMAD4_21799915_ChIP-Seq_A2780_Human1.03722155
123CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03176194
124PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.03034285
125P53_21459846_ChIP-Seq_SAOS-2_Human1.02882000
126SMAD4_21741376_ChIP-Seq_EPCs_Human1.02166063
127NFIB_24661679_ChIP-Seq_LUNG_Mouse1.01395467
128MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.01370017
129ELK1_19687146_ChIP-ChIP_HELA_Human0.99930658
130OCT4_18555785_Chip-Seq_ESCs_Mouse0.99854955
131HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.99642846
132SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.99508664
133P300_18555785_Chip-Seq_ESCs_Mouse0.99365209
134CTBP1_25329375_ChIP-Seq_LNCAP_Human0.98871172
135SOX9_26525672_Chip-Seq_HEART_Mouse0.98401127
136PHF8_20622854_ChIP-Seq_HELA_Human0.97699995
137SUZ12_27294783_Chip-Seq_ESCs_Mouse0.97537428
138FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.96592278
139ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96248036
140ER_23166858_ChIP-Seq_MCF-7_Human0.95837044
141EZH2_27294783_Chip-Seq_NPCs_Mouse0.95832687
142RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.95320578
143RAD21_21589869_ChIP-Seq_MESCs_Mouse0.95054568
144KLF4_18555785_Chip-Seq_ESCs_Mouse0.94607767
145P68_20966046_ChIP-Seq_HELA_Human0.94316595
146PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94101659
147CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.94055632
148TCF4_23295773_ChIP-Seq_U87_Human0.92753694
149POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.91721891
150SMAD3_21741376_ChIP-Seq_EPCs_Human0.91565973
151UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91526916
152CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91396117
153OCT4_21477851_ChIP-Seq_ESCs_Mouse0.91321710
154HOXB4_20404135_ChIP-ChIP_EML_Mouse0.90845573
155ERG_20517297_ChIP-Seq_VCAP_Human0.90710554
156GF1_26923725_Chip-Seq_HPCs_Mouse0.90442471
157STAT3_18555785_Chip-Seq_ESCs_Mouse0.90325698
158SUZ12_18555785_Chip-Seq_ESCs_Mouse0.89888213
159ESRRB_18555785_Chip-Seq_ESCs_Mouse0.89751220
160TBL1_22424771_ChIP-Seq_293T_Human0.89380649
161ERA_21632823_ChIP-Seq_H3396_Human0.89280032
162FUS_26573619_Chip-Seq_HEK293_Human0.89205325
163SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.89119596
164BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.88687384
165NFYB_21822215_ChIP-Seq_K562_Human0.88467726
166BCAT_22108803_ChIP-Seq_LS180_Human0.87062039
167EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.86881531
168OCT1_27270436_Chip-Seq_PROSTATE_Human0.85440963
169PU1_27457419_Chip-Seq_LIVER_Mouse0.85290056
170TOP2B_26459242_ChIP-Seq_MCF-7_Human0.84737498
171STAT1_20625510_ChIP-Seq_HELA_Human0.83172013
172SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.81212119
173PHF8_20622853_ChIP-Seq_HELA_Human0.80902740
174BCL6_27268052_Chip-Seq_Bcells_Human0.80572028
175CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.80305557
176FOXA1_25329375_ChIP-Seq_VCAP_Human0.79394330
177FOXA1_27270436_Chip-Seq_PROSTATE_Human0.79394330
178* SMC4_20622854_ChIP-Seq_HELA_Human0.78937406
179EWS_26573619_Chip-Seq_HEK293_Human0.77704275
180SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.74687151
181CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71493232
182FOXP1_21924763_ChIP-Seq_HESCs_Human0.71361828
183TBX5_21415370_ChIP-Seq_HL-1_Mouse0.71018120
184ETV1_20927104_ChIP-Seq_GIST48_Human0.70637255
185KLF4_18555785_ChIP-Seq_MESCs_Mouse0.70130210
186CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.69923646
187RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.69797624
188ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.69676272
189E2F1_20622854_ChIP-Seq_HELA_Human0.69300993
190CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.68830490

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive5.34015794
2MP0001929_abnormal_gametogenesis4.91322264
3MP0008877_abnormal_DNA_methylation4.49517489
4MP0002653_abnormal_ependyma_morphology3.42775203
5MP0003283_abnormal_digestive_organ3.40562530
6MP0002210_abnormal_sex_determination3.26543043
7MP0008789_abnormal_olfactory_epithelium3.05096458
8MP0003693_abnormal_embryo_hatching3.02936517
9MP0002102_abnormal_ear_morphology3.00094187
10MP0002161_abnormal_fertility/fecundity2.93479834
11MP0001145_abnormal_male_reproductive2.71736615
12MP0003111_abnormal_nucleus_morphology2.71691621
13MP0002234_abnormal_pharynx_morphology2.71341109
14MP0002132_abnormal_respiratory_system2.33407315
15MP0000653_abnormal_sex_gland2.32011010
16MP0010030_abnormal_orbit_morphology2.31053279
17MP0005623_abnormal_meninges_morphology2.25872864
18MP0002282_abnormal_trachea_morphology2.25620267
19MP0003718_maternal_effect2.21349010
20MP0003077_abnormal_cell_cycle2.15345081
21MP0003786_premature_aging2.13548351
22MP0008875_abnormal_xenobiotic_pharmacok2.10970088
23MP0001346_abnormal_lacrimal_gland2.04979333
24MP0005394_taste/olfaction_phenotype2.00449323
25MP0005499_abnormal_olfactory_system2.00449323
26MP0005410_abnormal_fertilization13.3918300
27MP0008007_abnormal_cellular_replicative1.96591617
28MP0002160_abnormal_reproductive_system1.95109681
29MP0004957_abnormal_blastocyst_morpholog1.87860677
30MP0000678_abnormal_parathyroid_gland1.83494506
31MP0005670_abnormal_white_adipose1.78224408
32MP0008057_abnormal_DNA_replication1.71262855
33MP0003950_abnormal_plasma_membrane1.67725477
34MP0004133_heterotaxia1.44435222
35MP0009379_abnormal_foot_pigmentation1.43670964
36MP0008995_early_reproductive_senescence1.41913578
37MP0009046_muscle_twitch1.33967900
38MP0001293_anophthalmia1.33349224
39MP0009053_abnormal_anal_canal1.27772232
40MP0003943_abnormal_hepatobiliary_system1.24305368
41MP0006036_abnormal_mitochondrial_physio1.10146453
42MP0000350_abnormal_cell_proliferation1.06590823
43MP0003656_abnormal_erythrocyte_physiolo1.06436976
44MP0003646_muscle_fatigue1.05190349
45MP0001529_abnormal_vocalization1.04620707
46MP0003115_abnormal_respiratory_system1.04015433
47MP0000537_abnormal_urethra_morphology1.02583473
48MP0003122_maternal_imprinting0.98574184
49MP0010307_abnormal_tumor_latency0.98116563
50MP0005551_abnormal_eye_electrophysiolog0.97319640
51MP0005395_other_phenotype0.96372849
52MP0000467_abnormal_esophagus_morphology0.95456282
53MP0000462_abnormal_digestive_system0.94939566
54MP0000358_abnormal_cell_content/0.94775109
55MP0004233_abnormal_muscle_weight0.94164002
56MP0000313_abnormal_cell_death0.91463882
57MP0005389_reproductive_system_phenotype0.90980061
58MP0004270_analgesia0.90820291
59MP0002085_abnormal_embryonic_tissue0.90634969
60MP0001697_abnormal_embryo_size0.89684340
61MP0001984_abnormal_olfaction0.89665064
62MP0002080_prenatal_lethality0.89022675
63MP0001730_embryonic_growth_arrest0.87970139
64MP0004742_abnormal_vestibular_system0.87115090
65MP0000383_abnormal_hair_follicle0.85811320
66MP0008058_abnormal_DNA_repair0.84877146
67MP0001188_hyperpigmentation0.84178759
68MP0002092_abnormal_eye_morphology0.83190415
69MP0009278_abnormal_bone_marrow0.82205628
70MP0000778_abnormal_nervous_system0.81745287
71MP0008004_abnormal_stomach_pH0.81631310
72MP0003806_abnormal_nucleotide_metabolis0.81185370
73MP0010094_abnormal_chromosome_stability0.80543930
74MP0005391_vision/eye_phenotype0.80526361
75MP0001672_abnormal_embryogenesis/_devel0.79141745
76MP0005380_embryogenesis_phenotype0.79141745
77MP0002019_abnormal_tumor_incidence0.77496787
78MP0000681_abnormal_thyroid_gland0.74754442
79MP0003942_abnormal_urinary_system0.74450880
80MP0003011_delayed_dark_adaptation0.72756680
81MP0002277_abnormal_respiratory_mucosa0.72741027
82MP0009697_abnormal_copulation0.70979393
83MP0009703_decreased_birth_body0.69255396
84MP0000490_abnormal_crypts_of0.68987016
85MP0003861_abnormal_nervous_system0.68217682
86MP0004043_abnormal_pH_regulation0.68192810
87MP0001765_abnormal_ion_homeostasis0.66018284
88MP0002751_abnormal_autonomic_nervous0.65613395
89MP0002249_abnormal_larynx_morphology0.64989077
90MP0001919_abnormal_reproductive_system0.64461348
91MP0003183_abnormal_peptide_metabolism0.63600812
92MP0003936_abnormal_reproductive_system0.62587334
93MP0001324_abnormal_eye_pigmentation0.61657226
94MP0004019_abnormal_vitamin_homeostasis0.61137155
95MP0006292_abnormal_olfactory_placode0.61067944
96MP0005253_abnormal_eye_physiology0.59591531
97MP0002152_abnormal_brain_morphology0.58518209
98MP0005248_abnormal_Harderian_gland0.57821997
99MP0005384_cellular_phenotype0.57621173
100MP0001727_abnormal_embryo_implantation0.57514320
101MP0005423_abnormal_somatic_nervous0.57352589
102MP0003315_abnormal_perineum_morphology0.57014070
103MP0003938_abnormal_ear_development0.55299624
104MP0003984_embryonic_growth_retardation0.54523866
105MP0009780_abnormal_chondrocyte_physiolo0.54432131
106MP0003329_amyloid_beta_deposits0.53780243
107MP0002064_seizures0.53585297
108MP0002095_abnormal_skin_pigmentation0.53452225
109MP0003634_abnormal_glial_cell0.53267205
110MP0002736_abnormal_nociception_after0.53138472
111MP0005195_abnormal_posterior_eye0.53094806
112MP0000534_abnormal_ureter_morphology0.52936845
113MP0005076_abnormal_cell_differentiation0.52766769
114MP0002272_abnormal_nervous_system0.52410466
115MP0006035_abnormal_mitochondrial_morpho0.52391771
116MP0000751_myopathy0.52085508
117MP0002088_abnormal_embryonic_growth/wei0.51333752
118MP0004145_abnormal_muscle_electrophysio0.50806306
119MP0000955_abnormal_spinal_cord0.49215811
120MP0004134_abnormal_chest_morphology0.49079672
121MP0001545_abnormal_hematopoietic_system0.48880253
122MP0005397_hematopoietic_system_phenotyp0.48880253
123MP0002932_abnormal_joint_morphology0.48878841
124MP0010678_abnormal_skin_adnexa0.47537155
125MP0003136_yellow_coat_color0.46973749
126MP0001440_abnormal_grooming_behavior0.46884057
127MP0005666_abnormal_adipose_tissue0.46316916
128MP0004147_increased_porphyrin_level0.45129734
129MP0003186_abnormal_redox_activity0.45008363
130MP0000566_synostosis0.44375972
131MP0005647_abnormal_sex_gland0.43662215
132MP0002752_abnormal_somatic_nervous0.43637972
133MP0000647_abnormal_sebaceous_gland0.43580175
134MP0002295_abnormal_pulmonary_circulatio0.43518648
135MP0005646_abnormal_pituitary_gland0.43360694
136MP0001485_abnormal_pinna_reflex0.42779561
137MP0008932_abnormal_embryonic_tissue0.42684849
138MP0002882_abnormal_neuron_morphology0.42361117
139MP0006072_abnormal_retinal_apoptosis0.42274468
140MP0002111_abnormal_tail_morphology0.42249274
141MP0005075_abnormal_melanosome_morpholog0.42086094
142MP0002233_abnormal_nose_morphology0.42062479
143MP0002697_abnormal_eye_size0.42044035
144MP0000049_abnormal_middle_ear0.41873126
145MP0000920_abnormal_myelination0.41492505
146MP0002084_abnormal_developmental_patter0.41249649
147MP0005377_hearing/vestibular/ear_phenot0.41036380
148MP0003878_abnormal_ear_physiology0.41036380
149MP0001486_abnormal_startle_reflex0.40525182
150MP0001968_abnormal_touch/_nociception0.40498710
151MP0005621_abnormal_cell_physiology0.40468972
152MP0003121_genomic_imprinting0.40337979
153MP0005501_abnormal_skin_physiology0.39601809
154MP0003937_abnormal_limbs/digits/tail_de0.38943956
155MP0000015_abnormal_ear_pigmentation0.38442379
156MP0003119_abnormal_digestive_system0.38074647
157MP0002116_abnormal_craniofacial_bone0.37445032
158MP0002928_abnormal_bile_duct0.37271506
159MP0000026_abnormal_inner_ear0.36606089
160MP0003635_abnormal_synaptic_transmissio0.34531507
161MP0003880_abnormal_central_pattern0.33224997
162MP0003699_abnormal_female_reproductive0.32898043
163MP0001340_abnormal_eyelid_morphology0.31906886
164MP0001119_abnormal_female_reproductive0.30554454
165MP0002229_neurodegeneration0.29827191
166MP0009745_abnormal_behavioral_response0.29685812

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.53562569
2Abnormal respiratory motile cilium morphology (HP:0005938)8.71397684
3Abnormal respiratory epithelium morphology (HP:0012253)8.71397684
4Rhinitis (HP:0012384)7.95393189
5Abnormal ciliary motility (HP:0012262)7.91376130
6Chronic bronchitis (HP:0004469)7.15725220
7Infertility (HP:0000789)5.77539103
8Nasal polyposis (HP:0100582)5.75545204
9Abnormality of the nasal mucosa (HP:0000433)4.72669852
10Nephronophthisis (HP:0000090)4.58512947
11Bronchiectasis (HP:0002110)4.52254589
12Bronchitis (HP:0012387)4.21993308
13Male infertility (HP:0003251)3.46296411
14Abnormality of the renal medulla (HP:0100957)3.45124259
15Molar tooth sign on MRI (HP:0002419)3.21263944
16Abnormality of midbrain morphology (HP:0002418)3.21263944
17Recurrent sinusitis (HP:0011108)3.08898852
18Tubulointerstitial nephritis (HP:0001970)3.03160667
19Recurrent otitis media (HP:0000403)3.03077729
20Medial flaring of the eyebrow (HP:0010747)2.97217278
21Postaxial foot polydactyly (HP:0001830)2.86373232
22Tubular atrophy (HP:0000092)2.73614717
23Abnormal spermatogenesis (HP:0008669)2.70026137
24Tubulointerstitial abnormality (HP:0001969)2.57227108
25Chromosomal breakage induced by crosslinking agents (HP:0003221)2.54805068
26Pancreatic fibrosis (HP:0100732)2.54023947
27Atelectasis (HP:0100750)2.47228566
28Gonadotropin excess (HP:0000837)2.46249144
29Chromsome breakage (HP:0040012)2.36397674
30Congenital hepatic fibrosis (HP:0002612)2.26988492
31Recurrent bronchitis (HP:0002837)2.26172033
32Volvulus (HP:0002580)2.24438806
33Abnormal gallbladder physiology (HP:0012438)2.23781891
34Cholecystitis (HP:0001082)2.23781891
35Stage 5 chronic kidney disease (HP:0003774)2.14526115
36Spontaneous abortion (HP:0005268)2.14356745
37True hermaphroditism (HP:0010459)2.11465905
38Gait imbalance (HP:0002141)2.09228531
39Tubulointerstitial fibrosis (HP:0005576)2.08836527
40Congenital primary aphakia (HP:0007707)2.06682560
41Fibular hypoplasia (HP:0003038)2.00606995
42Aplasia/Hypoplasia of the sacrum (HP:0008517)2.00285870
43Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2276819
44Dynein arm defect of respiratory motile cilia (HP:0012255)11.9296861
45Absent/shortened dynein arms (HP:0200106)11.9296861
46Oculomotor apraxia (HP:0000657)1.99024194
47Postaxial hand polydactyly (HP:0001162)1.98573169
48Male pseudohermaphroditism (HP:0000037)1.96731469
49Short nail (HP:0001799)1.96236603
50Hypoplasia of the capital femoral epiphysis (HP:0003090)1.94516159
51Azoospermia (HP:0000027)1.93434064
52Broad distal phalanx of finger (HP:0009836)1.93010076
53Dyschromatopsia (HP:0007641)1.90942106
54Abnormality of dentin (HP:0010299)1.90245189
55Median cleft lip (HP:0000161)1.88528510
56Abnormality of the lower motor neuron (HP:0002366)1.87627152
57Hyperactive renin-angiotensin system (HP:0000841)1.86463858
58Cystic liver disease (HP:0006706)1.86200810
59Decreased central vision (HP:0007663)1.86175252
60Aplasia/Hypoplasia of the tongue (HP:0010295)1.86002171
61Abnormal drinking behavior (HP:0030082)1.85649004
62Polydipsia (HP:0001959)1.85649004
63Abnormality of the renal cortex (HP:0011035)1.85246544
64Impulsivity (HP:0100710)1.85069804
65Occipital encephalocele (HP:0002085)1.84563415
66Small intestinal stenosis (HP:0012848)1.84368590
67Duodenal stenosis (HP:0100867)1.84368590
68Abnormality of permanent molar morphology (HP:0011071)1.81923448
69Abnormality of the dental root (HP:0006486)1.81923448
70Taurodontia (HP:0000679)1.81923448
71Chronic hepatic failure (HP:0100626)1.80669339
72Abnormal biliary tract physiology (HP:0012439)1.79176156
73Bile duct proliferation (HP:0001408)1.79176156
74Supernumerary spleens (HP:0009799)1.77225877
75Nephrogenic diabetes insipidus (HP:0009806)1.73183315
76Abnormality of molar (HP:0011077)1.72815986
77Abnormality of molar morphology (HP:0011070)1.72815986
78Aplasia/Hypoplasia of the uvula (HP:0010293)1.71648877
79Sloping forehead (HP:0000340)1.71535137
80Shoulder girdle muscle weakness (HP:0003547)1.70451500
81Chronic otitis media (HP:0000389)1.69225403
82Abnormality of chromosome stability (HP:0003220)1.69185925
83Pancreatic cysts (HP:0001737)1.68854972
84Chronic sinusitis (HP:0011109)1.68778236
85Aplasia/Hypoplasia of the lens (HP:0008063)1.68767905
86Short ribs (HP:0000773)1.68557137
87Facial cleft (HP:0002006)1.67014094
88Aganglionic megacolon (HP:0002251)1.66163345
89Abnormality of the preputium (HP:0100587)1.64020040
90Vaginal atresia (HP:0000148)1.63726017
91Abdominal situs inversus (HP:0003363)1.62491575
92Abnormality of abdominal situs (HP:0011620)1.62491575
93Abnormality of the dental pulp (HP:0006479)1.62323827
94Absent rod-and cone-mediated responses on ERG (HP:0007688)1.61752999
9511 pairs of ribs (HP:0000878)1.60316823
96Genital tract atresia (HP:0001827)1.60082495
97Multicystic kidney dysplasia (HP:0000003)1.59414179
98Type I transferrin isoform profile (HP:0003642)1.59165583
99Poor coordination (HP:0002370)1.57082020
100Bell-shaped thorax (HP:0001591)1.56683893
101Amyotrophic lateral sclerosis (HP:0007354)1.56608478
102Choroideremia (HP:0001139)1.55170608
103Oligodactyly (hands) (HP:0001180)1.54321715
104Holoprosencephaly (HP:0001360)1.54158360
105Preaxial hand polydactyly (HP:0001177)1.54009247
106Rimmed vacuoles (HP:0003805)1.53927815
107Absent epiphyses (HP:0010577)1.52364524
108Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.52364524
109Meckel diverticulum (HP:0002245)1.51196961
110Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.49673683
111Abnormal protein N-linked glycosylation (HP:0012347)1.49673683
112Abnormal protein glycosylation (HP:0012346)1.49673683
113Abnormal glycosylation (HP:0012345)1.49673683
114Increased nuchal translucency (HP:0010880)1.48112688
115Abnormality of cochlea (HP:0000375)1.47869006
116Abnormality of the ileum (HP:0001549)1.46373001
117Abnormality of renal excretion (HP:0011036)1.46289004
118Cleft eyelid (HP:0000625)1.43346301
119Spastic tetraparesis (HP:0001285)1.41566699
120Hepatocellular necrosis (HP:0001404)1.41472201
121Sensory axonal neuropathy (HP:0003390)1.41269748
122Abnormality of the duodenum (HP:0002246)1.40998065
123Aplasia/Hypoplasia of the fibula (HP:0006492)1.40933717
124Sclerocornea (HP:0000647)1.39633906
125Bilateral microphthalmos (HP:0007633)1.39601377
126Microglossia (HP:0000171)1.39403024
127Furrowed tongue (HP:0000221)1.38365416
128Difficulty running (HP:0009046)1.36079652
129Short thorax (HP:0010306)1.35970162
130Anencephaly (HP:0002323)1.35636779
131Impaired proprioception (HP:0010831)1.33536896
132Cone-rod dystrophy (HP:0000548)1.33207979
133Renal dysplasia (HP:0000110)1.33201243
134Absent frontal sinuses (HP:0002688)1.30625590
135Heterotopia (HP:0002282)1.30300241
136Nephropathy (HP:0000112)1.29968048
137Short femoral neck (HP:0100864)1.29626988

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.59673322
2PDK48.59673322
3PDK25.56124886
4TESK14.41479507
5PRKD33.42689562
6VRK23.41522404
7ICK3.23141871
8MST42.95228091
9CDK192.79773872
10PNCK2.71333916
11STK392.52528674
12WNK42.41958576
13BUB12.33019285
14STK162.22489335
15BRSK22.17407404
16PTK2B2.10145828
17MET1.99202104
18VRK11.91138862
19MAPK151.85728234
20EPHA21.83613392
21BRSK11.74913291
22NEK91.73032757
23SMG11.55029606
24CDC71.50326335
25EPHB21.47440638
26BCKDK1.44784233
27CDK81.35799592
28IRAK11.32359325
29TRIM281.28467137
30ARAF1.21768099
31NEK21.20136580
32DYRK1B1.19626779
33PRKCI1.18684914
34MST1R1.14050458
35STK381.10889421
36AURKB1.05854187
37WNK11.05771342
38NME10.97542244
39CSF1R0.96152747
40BCR0.96002980
41KSR10.93243815
42PDK10.93022166
43PLK30.90376891
44BMX0.90269375
45PINK10.89198456
46PASK0.87651053
47DYRK30.85361459
48MAPKAPK30.84886403
49NEK60.83993515
50PLK20.83942357
51SCYL20.81534838
52STK38L0.81424469
53LIMK10.80219946
54ZAK0.79613766
55PLK40.77401222
56NUAK10.75807784
57BRAF0.73661055
58TAF10.72926597
59TLK10.72525982
60CAMK1G0.70474847
61PAK20.69094771
62PIM20.67977993
63DAPK10.65762231
64TTK0.65169892
65WEE10.63119903
66CDK90.61744611
67CDK20.61402819
68RPS6KB20.57067478
69NEK10.56189796
70TSSK60.55898107
71IRAK20.55256312
72LRRK20.54386018
73SRPK10.54377037
74GRK10.54347270
75STK100.53139510
76EIF2AK10.53045721
77PRKCG0.51469079
78KDR0.51340494
79MAP4K20.51165620
80TYRO30.50823950
81MELK0.49832262
82PAK60.49586210
83NTRK20.48493701
84PDPK10.47122780
85CDK40.46718214
86MARK30.46660655
87CHEK20.46242631
88CSNK2A20.46230728
89MAP3K120.46048781
90CHEK10.45069541
91AKT20.43518204
92STK30.43312134
93CCNB10.43017051
94NME20.42764917
95MAP2K20.42075066
96ATR0.41855201
97LMTK20.40622268
98WNK30.37108640
99MAP3K30.36935841
100PRKDC0.36891917
101MAP3K20.36650778
102EPHB10.33471100
103ABL20.32940337
104ATM0.31789890
105MUSK0.29733872
106MARK20.29241364
107PAK10.29193967
108MAPK130.28838657
109RIPK10.27668085
110OXSR10.27502271
111FGR0.27148170
112AURKA0.26818212
113MAP3K100.26304417
114MINK10.25427581
115MAP3K110.24784081
116CSNK1D0.24506230
117CDK180.23034839
118ERBB20.21703454
119MARK10.21635907
120CDK150.21201547
121MTOR0.19615987
122TAOK10.18389571
123CDK11A0.17052227
124CDK140.16982179
125PRKCZ0.16240677
126YES10.13787577
127PLK10.13378153
128GSK3B0.12360042
129PRKG10.12299902
130MAP2K70.12023680
131PRKAA10.12009664
132NTRK30.11402517
133CASK0.10809161
134MAP3K50.10729543
135CAMKK10.10722125
136CAMK2A0.10128545
137PKN10.09990523
138MAP3K40.09982409
139MAPK100.09942129
140DYRK20.09021440
141CDK30.08981305
142CDK10.08825603
143RPS6KB10.08522301
144PBK0.08482073
145CDK50.08305300
146TESK20.08129665
147BMPR1B0.07779173
148MAP2K60.07631207
149MAPK80.07370908
150PRKCB0.07345717
151CSNK1E0.07239224
152PRKCQ0.07020328
153DYRK1A0.06891083
154STK110.06542801
155RPS6KA30.06272502
156PRKACB0.06180250
157MAPKAPK50.05978462
158PRKACG0.05972475
159CDK70.05785557
160CSNK2A10.05606664

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.67783143
2Vitamin B6 metabolism_Homo sapiens_hsa007505.20792933
3Mismatch repair_Homo sapiens_hsa034304.80839152
4Base excision repair_Homo sapiens_hsa034103.88331787
5Glycolysis / Gluconeogenesis_Homo sapiens_hsa000103.81563306
6Nucleotide excision repair_Homo sapiens_hsa034203.63503368
7Non-homologous end-joining_Homo sapiens_hsa034503.33619974
8Pyruvate metabolism_Homo sapiens_hsa006203.26796885
9Fatty acid biosynthesis_Homo sapiens_hsa000612.90685089
10Cell cycle_Homo sapiens_hsa041102.70090738
11Proteasome_Homo sapiens_hsa030502.60142568
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.51416729
13Linoleic acid metabolism_Homo sapiens_hsa005912.46266173
14Glucagon signaling pathway_Homo sapiens_hsa049222.44667962
15Propanoate metabolism_Homo sapiens_hsa006402.39322350
16Dorso-ventral axis formation_Homo sapiens_hsa043202.31307658
17Basal transcription factors_Homo sapiens_hsa030222.19100939
18Phenylalanine metabolism_Homo sapiens_hsa003602.13623710
19Fanconi anemia pathway_Homo sapiens_hsa034602.09101455
20Hedgehog signaling pathway_Homo sapiens_hsa043402.08745676
21Oocyte meiosis_Homo sapiens_hsa041142.05221319
22Sulfur relay system_Homo sapiens_hsa041221.99980780
23Pyrimidine metabolism_Homo sapiens_hsa002401.87910434
24Spliceosome_Homo sapiens_hsa030401.84649399
25Amphetamine addiction_Homo sapiens_hsa050311.74934032
26Basal cell carcinoma_Homo sapiens_hsa052171.74025300
27Cardiac muscle contraction_Homo sapiens_hsa042601.70454907
28Ether lipid metabolism_Homo sapiens_hsa005651.69881892
29Huntingtons disease_Homo sapiens_hsa050161.64786917
30Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.64079521
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.61499365
32Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.59324465
33Glycerophospholipid metabolism_Homo sapiens_hsa005641.55187716
34Parkinsons disease_Homo sapiens_hsa050121.54571240
35Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.54520894
36One carbon pool by folate_Homo sapiens_hsa006701.52034847
37Carbohydrate digestion and absorption_Homo sapiens_hsa049731.52019080
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.49944343
39Selenocompound metabolism_Homo sapiens_hsa004501.47059125
40Glycerolipid metabolism_Homo sapiens_hsa005611.46091834
41Tyrosine metabolism_Homo sapiens_hsa003501.40673982
42Phototransduction_Homo sapiens_hsa047441.37842592
43Pentose phosphate pathway_Homo sapiens_hsa000301.35595764
44Oxidative phosphorylation_Homo sapiens_hsa001901.31218949
45RNA polymerase_Homo sapiens_hsa030201.29809544
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.28595369
47Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.28155267
48Renin secretion_Homo sapiens_hsa049241.26297911
49Ribosome_Homo sapiens_hsa030101.25672356
50Glycosaminoglycan degradation_Homo sapiens_hsa005311.23719856
51Histidine metabolism_Homo sapiens_hsa003401.23448681
52PPAR signaling pathway_Homo sapiens_hsa033201.20739067
53Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.18243824
54Fructose and mannose metabolism_Homo sapiens_hsa000511.12978674
55Purine metabolism_Homo sapiens_hsa002301.10938440
56Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.08299448
57p53 signaling pathway_Homo sapiens_hsa041151.07558241
58Mineral absorption_Homo sapiens_hsa049781.06522917
59mRNA surveillance pathway_Homo sapiens_hsa030151.06058897
60beta-Alanine metabolism_Homo sapiens_hsa004101.02354985
61Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.00861239
62Fatty acid metabolism_Homo sapiens_hsa012121.00191679
63Wnt signaling pathway_Homo sapiens_hsa043100.99318244
64Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.99107550
65Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.96913450
66Homologous recombination_Homo sapiens_hsa034400.93335690
67Long-term potentiation_Homo sapiens_hsa047200.93195584
68Carbon metabolism_Homo sapiens_hsa012000.90409791
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.89891997
70Folate biosynthesis_Homo sapiens_hsa007900.89207855
71Drug metabolism - other enzymes_Homo sapiens_hsa009830.87645910
72N-Glycan biosynthesis_Homo sapiens_hsa005100.86132427
73Circadian entrainment_Homo sapiens_hsa047130.84733190
74Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.84437495
75Axon guidance_Homo sapiens_hsa043600.84325087
76Peroxisome_Homo sapiens_hsa041460.84040556
77Sphingolipid metabolism_Homo sapiens_hsa006000.83351819
78Calcium signaling pathway_Homo sapiens_hsa040200.82971625
79Insulin secretion_Homo sapiens_hsa049110.80179990
80Fat digestion and absorption_Homo sapiens_hsa049750.78670980
81Glutathione metabolism_Homo sapiens_hsa004800.78335664
82Cysteine and methionine metabolism_Homo sapiens_hsa002700.77368000
83Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.76958665
84Retinol metabolism_Homo sapiens_hsa008300.76114428
85Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.75462431
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.73507891
87Collecting duct acid secretion_Homo sapiens_hsa049660.73019400
88Regulation of autophagy_Homo sapiens_hsa041400.72106008
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71566042
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70838242
91Protein export_Homo sapiens_hsa030600.70164465
92Synaptic vesicle cycle_Homo sapiens_hsa047210.69797859
93Olfactory transduction_Homo sapiens_hsa047400.69397929
94Caffeine metabolism_Homo sapiens_hsa002320.66298830
95Glutamatergic synapse_Homo sapiens_hsa047240.65853662
96Gastric acid secretion_Homo sapiens_hsa049710.65749865
972-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.65015435
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63492414
99Arachidonic acid metabolism_Homo sapiens_hsa005900.61904496
100Estrogen signaling pathway_Homo sapiens_hsa049150.61901728
101Salivary secretion_Homo sapiens_hsa049700.60592493
102Fatty acid degradation_Homo sapiens_hsa000710.60411331
103Vascular smooth muscle contraction_Homo sapiens_hsa042700.59359691
104Steroid hormone biosynthesis_Homo sapiens_hsa001400.58581482
105Fatty acid elongation_Homo sapiens_hsa000620.56763384
106Biosynthesis of amino acids_Homo sapiens_hsa012300.56572970
107ABC transporters_Homo sapiens_hsa020100.56293523
108RNA transport_Homo sapiens_hsa030130.56058003
109Nicotine addiction_Homo sapiens_hsa050330.55116857
110Thyroid hormone synthesis_Homo sapiens_hsa049180.53770724
111Antigen processing and presentation_Homo sapiens_hsa046120.53414175
112Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.53207800
113Primary immunodeficiency_Homo sapiens_hsa053400.51728299
114Taste transduction_Homo sapiens_hsa047420.48744114
115Chemical carcinogenesis_Homo sapiens_hsa052040.48575062
116Bile secretion_Homo sapiens_hsa049760.47059927
117Systemic lupus erythematosus_Homo sapiens_hsa053220.43010548
118Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.42994440
119Dopaminergic synapse_Homo sapiens_hsa047280.41548778
120Cocaine addiction_Homo sapiens_hsa050300.41392196
121Inositol phosphate metabolism_Homo sapiens_hsa005620.40852561
122Metabolic pathways_Homo sapiens_hsa011000.40478766
123Melanogenesis_Homo sapiens_hsa049160.39990634
124Pancreatic secretion_Homo sapiens_hsa049720.39675890
125Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.38766584
126Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.38748448
127Oxytocin signaling pathway_Homo sapiens_hsa049210.38660447
128Central carbon metabolism in cancer_Homo sapiens_hsa052300.38493757
129Alcoholism_Homo sapiens_hsa050340.37998416
130Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.37611153
131Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.37102084
132Endocytosis_Homo sapiens_hsa041440.36224428
133Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.35346590
134cAMP signaling pathway_Homo sapiens_hsa040240.35346167
135Hippo signaling pathway_Homo sapiens_hsa043900.34748223
136SNARE interactions in vesicular transport_Homo sapiens_hsa041300.33899431
137Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.32601580
138Tight junction_Homo sapiens_hsa045300.32464049
139HTLV-I infection_Homo sapiens_hsa051660.31925588
140Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.31450830
141Protein digestion and absorption_Homo sapiens_hsa049740.29985417
142Morphine addiction_Homo sapiens_hsa050320.29714403
143Notch signaling pathway_Homo sapiens_hsa043300.29545333
144RNA degradation_Homo sapiens_hsa030180.29291057
145Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.28543531
146Alzheimers disease_Homo sapiens_hsa050100.28495905
147Circadian rhythm_Homo sapiens_hsa047100.28281469
148Steroid biosynthesis_Homo sapiens_hsa001000.27101010
149Sulfur metabolism_Homo sapiens_hsa009200.23131531
150Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.21802174
151Butanoate metabolism_Homo sapiens_hsa006500.18773165
152Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.17072066
153Epstein-Barr virus infection_Homo sapiens_hsa051690.16110392
154Viral carcinogenesis_Homo sapiens_hsa052030.13351363
155Arginine and proline metabolism_Homo sapiens_hsa003300.11843967
156Small cell lung cancer_Homo sapiens_hsa052220.11330065
157Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.10160624
158Transcriptional misregulation in cancer_Homo sapiens_hsa052020.08247605
159Pentose and glucuronate interconversions_Homo sapiens_hsa000400.07408444
160Starch and sucrose metabolism_Homo sapiens_hsa005000.06498614

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