Rank | Gene Set | Z-score |
---|---|---|
1 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.82155809 |
2 | positive regulation of interferon-alpha production (GO:0032727) | 4.64191147 |
3 | regulation of interferon-alpha production (GO:0032647) | 4.39036756 |
4 | regulation of RIG-I signaling pathway (GO:0039535) | 4.26167114 |
5 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.13886126 |
6 | bone remodeling (GO:0046849) | 3.72910011 |
7 | regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) | 3.67980451 |
8 | cellular response to virus (GO:0098586) | 3.59907145 |
9 | response to muramyl dipeptide (GO:0032495) | 3.56130310 |
10 | B cell receptor signaling pathway (GO:0050853) | 3.55415760 |
11 | embryonic process involved in female pregnancy (GO:0060136) | 3.40605948 |
12 | detection of molecule of bacterial origin (GO:0032490) | 3.38968109 |
13 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.38616438 |
14 | growth hormone receptor signaling pathway (GO:0060396) | 3.32482323 |
15 | Rap protein signal transduction (GO:0032486) | 3.29679752 |
16 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 3.16469119 |
17 | regulation of pigment cell differentiation (GO:0050932) | 3.14199078 |
18 | positive regulation of interferon-beta production (GO:0032728) | 3.13057744 |
19 | nuclear pore organization (GO:0006999) | 3.07876492 |
20 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.04380316 |
21 | neutrophil activation involved in immune response (GO:0002283) | 3.03893468 |
22 | cellular extravasation (GO:0045123) | 3.03760088 |
23 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.02959663 |
24 | myeloid dendritic cell activation (GO:0001773) | 3.02608108 |
25 | myoblast migration (GO:0051451) | 2.98744249 |
26 | positive regulation of smooth muscle cell migration (GO:0014911) | 2.98453126 |
27 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.98252400 |
28 | negative regulation of osteoblast proliferation (GO:0033689) | 2.95938104 |
29 | positive regulation of bone remodeling (GO:0046852) | 2.95913363 |
30 | positive regulation of bone resorption (GO:0045780) | 2.95913363 |
31 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.95236990 |
32 | hypotonic response (GO:0006971) | 2.95118032 |
33 | T cell lineage commitment (GO:0002360) | 2.95104067 |
34 | myeloid dendritic cell differentiation (GO:0043011) | 2.94695216 |
35 | macrophage activation involved in immune response (GO:0002281) | 2.94364763 |
36 | granulocyte activation (GO:0036230) | 2.93724523 |
37 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.89899788 |
38 | negative regulation of DNA repair (GO:0045738) | 2.89076080 |
39 | regulation of histone H3-K27 methylation (GO:0061085) | 2.88930679 |
40 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.86701907 |
41 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.84408016 |
42 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.83318302 |
43 | N-acetylneuraminate metabolic process (GO:0006054) | 2.82585261 |
44 | regulation of gamma-delta T cell activation (GO:0046643) | 2.82262350 |
45 | pinocytosis (GO:0006907) | 2.81868761 |
46 | response to laminar fluid shear stress (GO:0034616) | 2.78196681 |
47 | mesenchymal-epithelial cell signaling (GO:0060638) | 2.78169046 |
48 | cellular response to growth hormone stimulus (GO:0071378) | 2.77421672 |
49 | negative regulation of bone mineralization (GO:0030502) | 2.76284586 |
50 | morphogenesis of an epithelial sheet (GO:0002011) | 2.75587145 |
51 | dendritic cell chemotaxis (GO:0002407) | 2.75152473 |
52 | positive regulation of B cell differentiation (GO:0045579) | 2.74486986 |
53 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.74367214 |
54 | neutrophil activation (GO:0042119) | 2.73914028 |
55 | pore complex assembly (GO:0046931) | 2.72117002 |
56 | positive regulation of response to biotic stimulus (GO:0002833) | 2.71855212 |
57 | germinal center formation (GO:0002467) | 2.70248134 |
58 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.69897022 |
59 | detection of external biotic stimulus (GO:0098581) | 2.69587452 |
60 | histone H3-K36 demethylation (GO:0070544) | 2.68878227 |
61 | regulation of T-helper 1 cell differentiation (GO:0045625) | 2.68517838 |
62 | mannose metabolic process (GO:0006013) | 2.67397863 |
63 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.67390746 |
64 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.65050121 |
65 | negative regulation of cell killing (GO:0031342) | 2.65050121 |
66 | regulation of macrophage cytokine production (GO:0010935) | 2.64908771 |
67 | cell-substrate adherens junction assembly (GO:0007045) | 2.64906309 |
68 | focal adhesion assembly (GO:0048041) | 2.64906309 |
69 | positive regulation of interleukin-12 production (GO:0032735) | 2.64766784 |
70 | B cell homeostasis (GO:0001782) | 2.64305269 |
71 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.63887169 |
72 | cell-substrate junction assembly (GO:0007044) | 2.63792191 |
73 | cellular response to ethanol (GO:0071361) | 2.63315209 |
74 | detection of other organism (GO:0098543) | 2.62927623 |
75 | regulation of necroptotic process (GO:0060544) | 2.62776726 |
76 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.62094851 |
77 | T-helper cell differentiation (GO:0042093) | 2.61360815 |
78 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 2.61360815 |
79 | nuclear pore complex assembly (GO:0051292) | 2.60532651 |
80 | pericardium development (GO:0060039) | 2.59054231 |
81 | Notch signaling involved in heart development (GO:0061314) | 2.54495414 |
82 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.54167033 |
83 | response to host (GO:0075136) | 2.54167033 |
84 | response to host defenses (GO:0052200) | 2.54167033 |
85 | dendritic cell migration (GO:0036336) | 2.51911005 |
86 | melanin metabolic process (GO:0006582) | 2.51795048 |
87 | superoxide anion generation (GO:0042554) | 2.51729246 |
88 | negative regulation of viral genome replication (GO:0045071) | 2.50825899 |
89 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.50632247 |
90 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 2.50588354 |
91 | NIK/NF-kappaB signaling (GO:0038061) | 2.49644270 |
92 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.49119877 |
93 | negative regulation of interleukin-12 production (GO:0032695) | 2.48930960 |
94 | regulation of RNA export from nucleus (GO:0046831) | 2.48679022 |
95 | negative thymic T cell selection (GO:0045060) | 2.47878800 |
96 | regulation of B cell differentiation (GO:0045577) | 2.47224287 |
97 | B cell proliferation (GO:0042100) | 2.45642138 |
98 | negative regulation of fatty acid transport (GO:2000192) | 2.45491404 |
99 | glomerulus development (GO:0032835) | 2.44925990 |
100 | protein localization to endosome (GO:0036010) | 2.44896238 |
101 | regulation of protein heterodimerization activity (GO:0043497) | 2.42392521 |
102 | positive regulation of heat generation (GO:0031652) | 2.42132456 |
103 | I-kappaB phosphorylation (GO:0007252) | 2.41910484 |
104 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.41251234 |
105 | regulation of fever generation (GO:0031620) | 2.40682867 |
106 | stress fiber assembly (GO:0043149) | 2.40419456 |
107 | regulation of protein polyubiquitination (GO:1902914) | 2.39432295 |
108 | negative regulation of anoikis (GO:2000811) | 2.39303033 |
109 | T cell migration (GO:0072678) | 2.39075704 |
110 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.38953133 |
111 | myelin assembly (GO:0032288) | 2.38628826 |
112 | positive regulation by symbiont of host defense response (GO:0052509) | 2.38360286 |
113 | modulation by symbiont of host defense response (GO:0052031) | 2.38360286 |
114 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.38360286 |
115 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.38360286 |
116 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.38360286 |
117 | modulation by symbiont of host immune response (GO:0052553) | 2.38360286 |
118 | sequestering of extracellular ligand from receptor (GO:0035581) | 2.37906432 |
119 | histone H3-K9 demethylation (GO:0033169) | 2.37895446 |
120 | T-helper 1 type immune response (GO:0042088) | 2.37564422 |
121 | detection of biotic stimulus (GO:0009595) | 2.37243447 |
122 | negative regulation of biomineral tissue development (GO:0070168) | 2.36569235 |
123 | positive regulation of mRNA catabolic process (GO:0061014) | 2.36501843 |
124 | regulation of nucleobase-containing compound transport (GO:0032239) | 2.35059198 |
125 | cortical actin cytoskeleton organization (GO:0030866) | 2.34660088 |
126 | hepatocyte apoptotic process (GO:0097284) | 2.34527879 |
127 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.33739462 |
128 | ear development (GO:0043583) | 2.33726017 |
129 | positive regulation of macrophage cytokine production (GO:0060907) | 2.33450581 |
130 | detection of bacterium (GO:0016045) | 2.33164813 |
131 | adherens junction assembly (GO:0034333) | 2.32946830 |
132 | cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) | 2.32754959 |
133 | skin morphogenesis (GO:0043589) | 2.31028697 |
134 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.30561884 |
135 | response to host immune response (GO:0052572) | 2.30561884 |
136 | COPII vesicle coating (GO:0048208) | 2.29364674 |
137 | response to peptidoglycan (GO:0032494) | 2.29353474 |
138 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.29185025 |
139 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) | 2.29148853 |
140 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.29122982 |
141 | interkinetic nuclear migration (GO:0022027) | 2.28811381 |
142 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.28780426 |
143 | regulation of fibroblast apoptotic process (GO:2000269) | 2.28277962 |
144 | positive regulation of developmental pigmentation (GO:0048087) | 2.28181250 |
145 | retinal cone cell development (GO:0046549) | 2.27452966 |
146 | definitive hemopoiesis (GO:0060216) | 2.26611667 |
147 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.25621277 |
148 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.25509487 |
149 | spleen development (GO:0048536) | 2.25187373 |
150 | platelet-derived growth factor receptor signaling pathway (GO:0048008) | 2.24556501 |
151 | positive regulation of cytokine-mediated signaling pathway (GO:0001961) | 2.24526432 |
152 | negative T cell selection (GO:0043383) | 2.24491382 |
153 | regulation of activation of Janus kinase activity (GO:0010533) | 2.23695370 |
154 | histone lysine demethylation (GO:0070076) | 2.23639305 |
155 | chondrocyte development (GO:0002063) | 2.23420821 |
156 | regulation of interferon-beta production (GO:0032648) | 2.23047349 |
157 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.22858767 |
158 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.22801359 |
159 | response to type I interferon (GO:0034340) | 2.22742547 |
160 | collagen fibril organization (GO:0030199) | 2.22569110 |
161 | cytokine secretion (GO:0050663) | 2.21924761 |
162 | cellular response to type I interferon (GO:0071357) | 2.21579079 |
163 | type I interferon signaling pathway (GO:0060337) | 2.21579079 |
164 | histone demethylation (GO:0016577) | 2.20833754 |
165 | phospholipid translocation (GO:0045332) | 2.20601363 |
166 | lipid translocation (GO:0034204) | 2.20601363 |
167 | membrane raft organization (GO:0031579) | 2.20253446 |
168 | mesenchymal cell development (GO:0014031) | 2.19824484 |
169 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.18738523 |
170 | neural tube formation (GO:0001841) | 2.18643922 |
171 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 2.18489013 |
172 | alpha-beta T cell activation involved in immune response (GO:0002287) | 2.18489013 |
173 | T cell differentiation involved in immune response (GO:0002292) | 2.18489013 |
174 | pathway-restricted SMAD protein phosphorylation (GO:0060389) | 2.17018059 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 4.74781225 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.59549690 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.62155044 |
4 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.24633557 |
5 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.99243909 |
6 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.81984134 |
7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.64062998 |
8 | MYC_22102868_ChIP-Seq_BL_Human | 2.63452080 |
9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.61084326 |
10 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.59489923 |
11 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.32281796 |
12 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.29691385 |
13 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.19047645 |
14 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.08074672 |
15 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.06587513 |
16 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.00930753 |
17 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.98757692 |
18 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.95069587 |
19 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.87955740 |
20 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.87287608 |
21 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.82056303 |
22 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.80058985 |
23 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.79445711 |
24 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.77471282 |
25 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.77468418 |
26 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.76402159 |
27 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.74541793 |
28 | MYB_26560356_Chip-Seq_TH1_Human | 1.74087746 |
29 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.72874414 |
30 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.70452283 |
31 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.69912907 |
32 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.65040611 |
33 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.62414132 |
34 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.61765992 |
35 | MAF_26560356_Chip-Seq_TH1_Human | 1.60247082 |
36 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.59323735 |
37 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.59171468 |
38 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.58740446 |
39 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.57181713 |
40 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.54118480 |
41 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.53541973 |
42 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.52763473 |
43 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.52530566 |
44 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.51763468 |
45 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.49771687 |
46 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.49034574 |
47 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.49034574 |
48 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.48732400 |
49 | SPI1_23127762_ChIP-Seq_K562_Human | 1.48473308 |
50 | RXR_22108803_ChIP-Seq_LS180_Human | 1.45486878 |
51 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.45131785 |
52 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.44846892 |
53 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.40852678 |
54 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.39926169 |
55 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.38328851 |
56 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.37570410 |
57 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.36744236 |
58 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.36623800 |
59 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.36533435 |
60 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.34903612 |
61 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.34135366 |
62 | TP53_16413492_ChIP-PET_HCT116_Human | 1.33615682 |
63 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.32966284 |
64 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.32606905 |
65 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.32449424 |
66 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.32430062 |
67 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.31997911 |
68 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.31376375 |
69 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.31268816 |
70 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.31268816 |
71 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.29852043 |
72 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.29305600 |
73 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.27561704 |
74 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.27248299 |
75 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.27235587 |
76 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.27230455 |
77 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.24123825 |
78 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.24059276 |
79 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.23008238 |
80 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.22095175 |
81 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.20953420 |
82 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.18436292 |
83 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.18349254 |
84 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.18328749 |
85 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.17842820 |
86 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.17535748 |
87 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.17429950 |
88 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.16741913 |
89 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.15733031 |
90 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15650675 |
91 | UTX_26944678_Chip-Seq_JUKART_Human | 1.15132518 |
92 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.14928185 |
93 | CJUN_26792858_Chip-Seq_BT549_Human | 1.14317910 |
94 | P300_19829295_ChIP-Seq_ESCs_Human | 1.13418379 |
95 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.13040588 |
96 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.12908142 |
97 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.12648987 |
98 | GATA1_22025678_ChIP-Seq_K562_Human | 1.11480886 |
99 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.11344381 |
100 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.11259724 |
101 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10989378 |
102 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.10781214 |
103 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.10470695 |
104 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.10315244 |
105 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.10039876 |
106 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.09867438 |
107 | GATA1_19941826_ChIP-Seq_K562_Human | 1.09607360 |
108 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.08285325 |
109 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.08265212 |
110 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.07622808 |
111 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.07413232 |
112 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.07410773 |
113 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.07400765 |
114 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.06953798 |
115 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.06803946 |
116 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.05576035 |
117 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.05473532 |
118 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.05455329 |
119 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.03903506 |
120 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.03263771 |
121 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.02907005 |
122 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.01961940 |
123 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.01079504 |
124 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.00956847 |
125 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.00956847 |
126 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.00077459 |
127 | GATA2_19941826_ChIP-Seq_K562_Human | 0.98919617 |
128 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.98359302 |
129 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.97306882 |
130 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.97049321 |
131 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.96935965 |
132 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.96233951 |
133 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.95722507 |
134 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.95207041 |
135 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.94365054 |
136 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.93914422 |
137 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 0.93637415 |
138 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.93246213 |
139 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92803271 |
140 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.92587593 |
141 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.92124053 |
142 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91653223 |
143 | STAT3_23295773_ChIP-Seq_U87_Human | 0.91537941 |
144 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.90272471 |
145 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 0.87577010 |
146 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.87461806 |
147 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.87111816 |
148 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.86914705 |
149 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.85965151 |
150 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.85376728 |
151 | MYB_26560356_Chip-Seq_TH2_Human | 0.85254381 |
152 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.84966751 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 3.14082263 |
2 | MP0002009_preneoplasia | 2.99728951 |
3 | MP0001348_abnormal_lacrimal_gland | 2.91938620 |
4 | MP0001835_abnormal_antigen_presentation | 2.84027259 |
5 | MP0000372_irregular_coat_pigmentation | 2.83156648 |
6 | MP0005275_abnormal_skin_tensile | 2.77944166 |
7 | MP0004381_abnormal_hair_follicle | 2.68635348 |
8 | MP0003300_gastrointestinal_ulcer | 2.65586937 |
9 | MP0002138_abnormal_hepatobiliary_system | 2.57824161 |
10 | MP0005408_hypopigmentation | 2.45703935 |
11 | MP0000569_abnormal_digit_pigmentation | 2.45000123 |
12 | MP0002006_tumorigenesis | 2.40925290 |
13 | MP0003724_increased_susceptibility_to | 2.38949467 |
14 | MP0003303_peritoneal_inflammation | 2.32872053 |
15 | MP0010352_gastrointestinal_tract_polyps | 2.32264626 |
16 | MP0002148_abnormal_hypersensitivity_rea | 2.32040112 |
17 | MP0002166_altered_tumor_susceptibility | 2.29053835 |
18 | MP0008057_abnormal_DNA_replication | 2.27442283 |
19 | MP0003566_abnormal_cell_adhesion | 2.19099900 |
20 | MP0003436_decreased_susceptibility_to | 2.09317958 |
21 | MP0005671_abnormal_response_to | 2.07544865 |
22 | MP0002396_abnormal_hematopoietic_system | 2.04390415 |
23 | MP0004510_myositis | 2.01308707 |
24 | MP0002254_reproductive_system_inflammat | 2.00162195 |
25 | MP0002877_abnormal_melanocyte_morpholog | 1.93748609 |
26 | MP0009785_altered_susceptibility_to | 1.93035465 |
27 | MP0005451_abnormal_body_composition | 1.89485296 |
28 | MP0003136_yellow_coat_color | 1.88973398 |
29 | MP0005000_abnormal_immune_tolerance | 1.87492437 |
30 | MP0003279_aneurysm | 1.86318313 |
31 | MP0001958_emphysema | 1.80289452 |
32 | MP0003950_abnormal_plasma_membrane | 1.77883820 |
33 | MP0001790_abnormal_immune_system | 1.72444819 |
34 | MP0005387_immune_system_phenotype | 1.72444819 |
35 | MP0002419_abnormal_innate_immunity | 1.69716201 |
36 | MP0005171_absent_coat_pigmentation | 1.69514226 |
37 | MP0002452_abnormal_antigen_presenting | 1.68699208 |
38 | MP0004808_abnormal_hematopoietic_stem | 1.67217824 |
39 | MP0002998_abnormal_bone_remodeling | 1.66589247 |
40 | MP0006054_spinal_hemorrhage | 1.66018228 |
41 | MP0000371_diluted_coat_color | 1.64814286 |
42 | MP0005076_abnormal_cell_differentiation | 1.61403414 |
43 | MP0003091_abnormal_cell_migration | 1.54363815 |
44 | MP0000767_abnormal_smooth_muscle | 1.53018334 |
45 | MP0005075_abnormal_melanosome_morpholog | 1.52957605 |
46 | MP0000015_abnormal_ear_pigmentation | 1.51079364 |
47 | MP0001800_abnormal_humoral_immune | 1.46210772 |
48 | MP0005503_abnormal_tendon_morphology | 1.45757247 |
49 | MP0005257_abnormal_intraocular_pressure | 1.44322336 |
50 | MP0002933_joint_inflammation | 1.44255344 |
51 | MP0008438_abnormal_cutaneous_collagen | 1.43527362 |
52 | MP0002723_abnormal_immune_serum | 1.42952496 |
53 | MP0001346_abnormal_lacrimal_gland | 1.41418510 |
54 | MP0002177_abnormal_outer_ear | 1.40593736 |
55 | MP0000566_synostosis | 1.39139707 |
56 | MP0005025_abnormal_response_to | 1.36641207 |
57 | MP0000685_abnormal_immune_system | 1.35937399 |
58 | MP0001819_abnormal_immune_cell | 1.34767085 |
59 | MP0005023_abnormal_wound_healing | 1.30376783 |
60 | MP0003453_abnormal_keratinocyte_physiol | 1.29977016 |
61 | MP0002277_abnormal_respiratory_mucosa | 1.29952954 |
62 | MP0002420_abnormal_adaptive_immunity | 1.29824589 |
63 | MP0003385_abnormal_body_wall | 1.29586992 |
64 | MP0002928_abnormal_bile_duct | 1.28466517 |
65 | MP0001879_abnormal_lymphatic_vessel | 1.28042536 |
66 | MP0003191_abnormal_cellular_cholesterol | 1.25562252 |
67 | MP0003941_abnormal_skin_development | 1.24973970 |
68 | MP0002168_other_aberrant_phenotype | 1.24750427 |
69 | MP0010234_abnormal_vibrissa_follicle | 1.22913186 |
70 | MP0001324_abnormal_eye_pigmentation | 1.21354618 |
71 | MP0001188_hyperpigmentation | 1.19116319 |
72 | MP0003448_altered_tumor_morphology | 1.18676533 |
73 | MP0003828_pulmonary_edema | 1.17770233 |
74 | MP0002163_abnormal_gland_morphology | 1.17629542 |
75 | MP0004782_abnormal_surfactant_physiolog | 1.16504813 |
76 | MP0000858_altered_metastatic_potential | 1.15403242 |
77 | MP0005248_abnormal_Harderian_gland | 1.14654416 |
78 | MP0008260_abnormal_autophagy | 1.14332993 |
79 | MP0005623_abnormal_meninges_morphology | 1.13614662 |
80 | MP0000516_abnormal_urinary_system | 1.12783099 |
81 | MP0005367_renal/urinary_system_phenotyp | 1.12783099 |
82 | MP0009333_abnormal_splenocyte_physiolog | 1.12100714 |
83 | MP0003763_abnormal_thymus_physiology | 1.11601856 |
84 | MP0005621_abnormal_cell_physiology | 1.09926772 |
85 | MP0003656_abnormal_erythrocyte_physiolo | 1.09238829 |
86 | MP0005164_abnormal_response_to | 1.08351471 |
87 | MP0009764_decreased_sensitivity_to | 1.05707600 |
88 | MP0001853_heart_inflammation | 1.05464497 |
89 | MP0002075_abnormal_coat/hair_pigmentati | 1.03528156 |
90 | MP0002095_abnormal_skin_pigmentation | 1.02389593 |
91 | MP0001851_eye_inflammation | 1.01777521 |
92 | MP0001533_abnormal_skeleton_physiology | 1.01519607 |
93 | MP0000733_abnormal_muscle_development | 1.01024335 |
94 | MP0004883_abnormal_blood_vessel | 1.00971125 |
95 | MP0010307_abnormal_tumor_latency | 1.00385295 |
96 | MP0002722_abnormal_immune_system | 0.99764035 |
97 | MP0003942_abnormal_urinary_system | 0.99577312 |
98 | MP0001186_pigmentation_phenotype | 0.99308308 |
99 | MP0003172_abnormal_lysosome_physiology | 0.99084083 |
100 | MP0000703_abnormal_thymus_morphology | 0.97624226 |
101 | MP0003221_abnormal_cardiomyocyte_apopto | 0.97451043 |
102 | MP0000689_abnormal_spleen_morphology | 0.96607886 |
103 | MP0001661_extended_life_span | 0.95601012 |
104 | MP0003943_abnormal_hepatobiliary_system | 0.95531818 |
105 | MP0003045_fibrosis | 0.95131980 |
106 | MP0000716_abnormal_immune_system | 0.93668092 |
107 | MP0005310_abnormal_salivary_gland | 0.93494759 |
108 | MP0001915_intracranial_hemorrhage | 0.91589581 |
109 | MP0009250_abnormal_appendicular_skeleto | 0.91407979 |
110 | MP0002429_abnormal_blood_cell | 0.90456029 |
111 | MP0000432_abnormal_head_morphology | 0.89577861 |
112 | MP0005197_abnormal_uvea_morphology | 0.89156125 |
113 | MP0005390_skeleton_phenotype | 0.88970709 |
114 | MP0008004_abnormal_stomach_pH | 0.88617505 |
115 | MP0002405_respiratory_system_inflammati | 0.87629845 |
116 | MP0005058_abnormal_lysosome_morphology | 0.87547384 |
117 | MP0000465_gastrointestinal_hemorrhage | 0.86728963 |
118 | MP0009697_abnormal_copulation | 0.86648542 |
119 | MP0002398_abnormal_bone_marrow | 0.85900022 |
120 | MP0005409_darkened_coat_color | 0.84008238 |
121 | MP0000627_abnormal_mammary_gland | 0.82646373 |
122 | MP0004947_skin_inflammation | 0.82237006 |
123 | MP0003252_abnormal_bile_duct | 0.82226128 |
124 | MP0010155_abnormal_intestine_physiology | 0.81234933 |
125 | MP0004185_abnormal_adipocyte_glucose | 0.79645790 |
126 | MP0005174_abnormal_tail_pigmentation | 0.79097001 |
127 | MP0001919_abnormal_reproductive_system | 0.78862446 |
128 | MP0005551_abnormal_eye_electrophysiolog | 0.78774612 |
129 | MP0001545_abnormal_hematopoietic_system | 0.78331834 |
130 | MP0005397_hematopoietic_system_phenotyp | 0.78331834 |
131 | MP0004084_abnormal_cardiac_muscle | 0.77541735 |
132 | MP0002060_abnormal_skin_morphology | 0.77138390 |
133 | MP0002086_abnormal_extraembryonic_tissu | 0.76546422 |
134 | MP0005464_abnormal_platelet_physiology | 0.76223002 |
135 | MP0005395_other_phenotype | 0.75303937 |
136 | MP0003011_delayed_dark_adaptation | 0.73564219 |
137 | MP0001845_abnormal_inflammatory_respons | 0.73401902 |
138 | MP0002092_abnormal_eye_morphology | 0.72142467 |
139 | MP0002896_abnormal_bone_mineralization | 0.72099850 |
140 | MP0005084_abnormal_gallbladder_morpholo | 0.71241541 |
141 | MP0004272_abnormal_basement_membrane | 0.71170801 |
142 | MP0003795_abnormal_bone_structure | 0.69603111 |
143 | MP0001849_ear_inflammation | 0.69395973 |
144 | MP0002128_abnormal_blood_circulation | 0.69391172 |
145 | MP0000003_abnormal_adipose_tissue | 0.69382113 |
146 | MP0003868_abnormal_feces_composition | 0.68597668 |
147 | MP0009278_abnormal_bone_marrow | 0.68105708 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Spinal cord lesions (HP:0100561) | 4.58618283 |
2 | Syringomyelia (HP:0003396) | 4.58618283 |
3 | Mediastinal lymphadenopathy (HP:0100721) | 3.92089985 |
4 | Absent frontal sinuses (HP:0002688) | 3.83877547 |
5 | Protrusio acetabuli (HP:0003179) | 3.72982436 |
6 | Aortic aneurysm (HP:0004942) | 3.63149090 |
7 | Aortic dissection (HP:0002647) | 3.55097338 |
8 | Chorioretinal atrophy (HP:0000533) | 3.43729903 |
9 | Spondylolisthesis (HP:0003302) | 3.22137950 |
10 | Eczematoid dermatitis (HP:0000976) | 3.15434991 |
11 | Oligodontia (HP:0000677) | 3.07101492 |
12 | Optic neuritis (HP:0100653) | 2.95250261 |
13 | Retrobulbar optic neuritis (HP:0100654) | 2.95250261 |
14 | Myocardial infarction (HP:0001658) | 2.94898840 |
15 | Abnormality of the nasal septum (HP:0000419) | 2.94145877 |
16 | Midline defect of the nose (HP:0004122) | 2.93346788 |
17 | Pigmentary retinal degeneration (HP:0001146) | 2.87889840 |
18 | Recurrent abscess formation (HP:0002722) | 2.87677199 |
19 | Arterial tortuosity (HP:0005116) | 2.86166889 |
20 | Dilatation of the ascending aorta (HP:0005111) | 2.84933941 |
21 | Vascular tortuosity (HP:0004948) | 2.84518155 |
22 | Abnormality of the fingertips (HP:0001211) | 2.73064949 |
23 | Recurrent bacterial skin infections (HP:0005406) | 2.72465152 |
24 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.71858982 |
25 | Osteolytic defects of the hand bones (HP:0009699) | 2.71858982 |
26 | Periodontitis (HP:0000704) | 2.69563166 |
27 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.68215218 |
28 | Abnormality of the frontal sinuses (HP:0002687) | 2.67991861 |
29 | Mitral valve prolapse (HP:0001634) | 2.65755851 |
30 | Congenital stationary night blindness (HP:0007642) | 2.63736428 |
31 | Colitis (HP:0002583) | 2.58199549 |
32 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.56456539 |
33 | Autoimmune thrombocytopenia (HP:0001973) | 2.54698729 |
34 | Vertebral compression fractures (HP:0002953) | 2.54430119 |
35 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 2.54121155 |
36 | Selective tooth agenesis (HP:0001592) | 2.53972996 |
37 | Stomatitis (HP:0010280) | 2.52592305 |
38 | Abnormality of the peritoneum (HP:0002585) | 2.52503475 |
39 | Overgrowth (HP:0001548) | 2.50566136 |
40 | Orchitis (HP:0100796) | 2.48888301 |
41 | Gastrointestinal infarctions (HP:0005244) | 2.42477374 |
42 | Thoracolumbar scoliosis (HP:0002944) | 2.40444983 |
43 | Pulmonary artery stenosis (HP:0004415) | 2.40274741 |
44 | Spontaneous hematomas (HP:0007420) | 2.37731891 |
45 | Thick nail (HP:0001805) | 2.36217643 |
46 | Pulmonary infiltrates (HP:0002113) | 2.35979391 |
47 | Mitral stenosis (HP:0001718) | 2.32858233 |
48 | Narrow palate (HP:0000189) | 2.32098252 |
49 | Arterial thrombosis (HP:0004420) | 2.29536285 |
50 | Recurrent fungal infections (HP:0002841) | 2.29099295 |
51 | Wormian bones (HP:0002645) | 2.28456018 |
52 | Asymmetry of the thorax (HP:0001555) | 2.28014345 |
53 | Cerebral aneurysm (HP:0004944) | 2.27342141 |
54 | Persistence of primary teeth (HP:0006335) | 2.27224587 |
55 | Alveolar cell carcinoma (HP:0006519) | 2.27146311 |
56 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.26135445 |
57 | Dyschromatopsia (HP:0007641) | 2.23507658 |
58 | Viral hepatitis (HP:0006562) | 2.23375121 |
59 | Gingivitis (HP:0000230) | 2.20297682 |
60 | Myositis (HP:0100614) | 2.19853455 |
61 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.19487303 |
62 | Aneurysm (HP:0002617) | 2.16840956 |
63 | Meningitis (HP:0001287) | 2.16667344 |
64 | Prostate neoplasm (HP:0100787) | 2.15836555 |
65 | Vasculitis (HP:0002633) | 2.15261825 |
66 | Genu recurvatum (HP:0002816) | 2.14426214 |
67 | Emphysema (HP:0002097) | 2.12619407 |
68 | Soft skin (HP:0000977) | 2.10850625 |
69 | Attenuation of retinal blood vessels (HP:0007843) | 2.09009047 |
70 | Gingival bleeding (HP:0000225) | 2.08490769 |
71 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.07565350 |
72 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.06555478 |
73 | Porencephaly (HP:0002132) | 2.04181282 |
74 | Gastrointestinal stroma tumor (HP:0100723) | 2.04157524 |
75 | Acute myeloid leukemia (HP:0004808) | 2.04065437 |
76 | Submucous cleft hard palate (HP:0000176) | 2.03892611 |
77 | Hematochezia (HP:0002573) | 2.01955236 |
78 | Basal ganglia calcification (HP:0002135) | 1.99733574 |
79 | Agammaglobulinemia (HP:0004432) | 1.98704995 |
80 | Bladder diverticulum (HP:0000015) | 1.97624456 |
81 | Short nail (HP:0001799) | 1.97214991 |
82 | Blue sclerae (HP:0000592) | 1.97077446 |
83 | Lip pit (HP:0100267) | 1.95779442 |
84 | Congenital sensorineural hearing impairment (HP:0008527) | 1.93692225 |
85 | Large earlobe (HP:0009748) | 1.93411606 |
86 | Dislocated radial head (HP:0003083) | 1.93192126 |
87 | Cellulitis (HP:0100658) | 1.92411928 |
88 | Follicular hyperkeratosis (HP:0007502) | 1.90320226 |
89 | Increased variability in muscle fiber diameter (HP:0003557) | 1.89632956 |
90 | Recurrent skin infections (HP:0001581) | 1.88994653 |
91 | IgA deficiency (HP:0002720) | 1.88560382 |
92 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.88382850 |
93 | Short 4th metacarpal (HP:0010044) | 1.88382850 |
94 | Broad ribs (HP:0000885) | 1.87924282 |
95 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.87880933 |
96 | Recurrent cutaneous fungal infections (HP:0011370) | 1.87880933 |
97 | T lymphocytopenia (HP:0005403) | 1.87265925 |
98 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.86538086 |
99 | Peritonitis (HP:0002586) | 1.86404681 |
100 | Thyroiditis (HP:0100646) | 1.85758751 |
101 | Inflammation of the large intestine (HP:0002037) | 1.85710533 |
102 | Abnormality of the pleura (HP:0002103) | 1.83173001 |
103 | Recurrent viral infections (HP:0004429) | 1.82661476 |
104 | Joint laxity (HP:0001388) | 1.82650866 |
105 | Delayed closure of the anterior fontanelle (HP:0001476) | 1.82562611 |
106 | Subacute progressive viral hepatitis (HP:0006572) | 1.82360778 |
107 | Fragile skin (HP:0001030) | 1.82351126 |
108 | Cone-rod dystrophy (HP:0000548) | 1.81607581 |
109 | Abnormality of incisor morphology (HP:0011063) | 1.81494883 |
110 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.80934752 |
111 | Portal hypertension (HP:0001409) | 1.79514684 |
112 | Relative macrocephaly (HP:0004482) | 1.79418311 |
113 | Gastrointestinal inflammation (HP:0004386) | 1.79399680 |
114 | Infantile muscular hypotonia (HP:0008947) | 1.79089244 |
115 | Spinal rigidity (HP:0003306) | 1.78646957 |
116 | Biconcave vertebral bodies (HP:0004586) | 1.78046741 |
117 | Abnormality of the hepatic vasculature (HP:0006707) | 1.77863231 |
118 | Ankyloglossia (HP:0010296) | 1.76283119 |
119 | Autoimmune hemolytic anemia (HP:0001890) | 1.76182403 |
120 | Increased connective tissue (HP:0009025) | 1.75755221 |
121 | Cervical subluxation (HP:0003308) | 1.75424923 |
122 | Vitreoretinal degeneration (HP:0000655) | 1.75124850 |
123 | Type 1 muscle fiber predominance (HP:0003803) | 1.73716795 |
124 | Osteomyelitis (HP:0002754) | 1.73259417 |
125 | Stomach cancer (HP:0012126) | 1.73225675 |
126 | Neonatal short-limb short stature (HP:0008921) | 1.72618125 |
127 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.71550844 |
128 | Dysmetric saccades (HP:0000641) | 1.71443361 |
129 | Abnormality of oral frenula (HP:0000190) | 1.71437861 |
130 | Increased IgE level (HP:0003212) | 1.71137510 |
131 | Abnormality of macrophages (HP:0004311) | 1.70793580 |
132 | Fatigue (HP:0012378) | 1.70649000 |
133 | Natal tooth (HP:0000695) | 1.70262220 |
134 | Ankle contracture (HP:0006466) | 1.69701234 |
135 | White forelock (HP:0002211) | 1.69540826 |
136 | Abnormality of T cell number (HP:0011839) | 1.69281968 |
137 | Distal lower limb amyotrophy (HP:0008944) | 1.69240496 |
138 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.68812375 |
139 | Increased corneal curvature (HP:0100692) | 1.68770629 |
140 | Keratoconus (HP:0000563) | 1.68770629 |
141 | Bone pain (HP:0002653) | 1.68101699 |
142 | Chronic obstructive pulmonary disease (HP:0006510) | 1.67740446 |
143 | Obstructive lung disease (HP:0006536) | 1.67740446 |
144 | Long eyelashes (HP:0000527) | 1.67737769 |
145 | Keratoconjunctivitis sicca (HP:0001097) | 1.67237076 |
146 | Flat acetabular roof (HP:0003180) | 1.67141729 |
147 | Decreased central vision (HP:0007663) | 1.66523762 |
148 | Ulnar bowing (HP:0003031) | 1.65885656 |
149 | Abnormality of the radial head (HP:0003995) | 1.65840773 |
150 | Increased number of teeth (HP:0011069) | 1.65512882 |
151 | Aortic regurgitation (HP:0001659) | 1.65061573 |
152 | Premature rupture of membranes (HP:0001788) | 1.64886171 |
153 | Leukocytosis (HP:0001974) | 1.64498117 |
154 | Plagiocephaly (HP:0001357) | 1.63625595 |
155 | Thin bony cortex (HP:0002753) | 1.63235231 |
156 | Clubbing of toes (HP:0100760) | 1.62921398 |
157 | Atrophic scars (HP:0001075) | 1.62018928 |
158 | Transitional cell carcinoma of the bladder (HP:0006740) | 1.60067377 |
159 | Vertebral arch anomaly (HP:0008438) | 1.59751026 |
160 | Hyperextensible skin (HP:0000974) | 1.58544882 |
161 | Abnormality of the thoracic spine (HP:0100711) | 1.58232494 |
162 | Hemoptysis (HP:0002105) | 1.57472349 |
163 | Abnormality of the lumbar spine (HP:0100712) | 1.57453514 |
164 | Cupped ribs (HP:0000887) | 1.56703485 |
165 | Increased IgM level (HP:0003496) | 1.55965739 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP3K14 | 5.04090194 |
2 | BRD4 | 3.17826058 |
3 | MKNK2 | 3.03356617 |
4 | LATS1 | 2.35719024 |
5 | PDGFRA | 2.27427799 |
6 | MAP3K10 | 2.25789523 |
7 | NEK9 | 2.18782381 |
8 | IRAK4 | 2.18195524 |
9 | PRPF4B | 2.13783445 |
10 | IKBKB | 2.09495809 |
11 | MAP3K13 | 2.08371015 |
12 | CHUK | 2.08117074 |
13 | MAP2K3 | 2.07151855 |
14 | YES1 | 2.03233976 |
15 | EEF2K | 2.01831587 |
16 | JAK3 | 2.00998081 |
17 | MKNK1 | 1.99845058 |
18 | FGFR4 | 1.97668351 |
19 | TRIB3 | 1.90077651 |
20 | IRAK3 | 1.88198791 |
21 | PIK3CG | 1.85308285 |
22 | NUAK1 | 1.83308175 |
23 | IKBKE | 1.77310175 |
24 | CASK | 1.71393807 |
25 | FGFR3 | 1.64507663 |
26 | ZAK | 1.60462796 |
27 | TXK | 1.58313662 |
28 | ERN1 | 1.57222918 |
29 | MAP4K1 | 1.56810340 |
30 | ICK | 1.55447050 |
31 | FRK | 1.55083394 |
32 | JAK1 | 1.54816964 |
33 | SGK2 | 1.51195750 |
34 | PIM1 | 1.51123797 |
35 | CDK9 | 1.48188156 |
36 | TBK1 | 1.38892151 |
37 | RIPK4 | 1.35137877 |
38 | EPHA3 | 1.34945572 |
39 | EIF2AK2 | 1.33099797 |
40 | CDK12 | 1.32630831 |
41 | BMX | 1.32354827 |
42 | MUSK | 1.28919692 |
43 | BMPR2 | 1.25306390 |
44 | SGK3 | 1.22435556 |
45 | KSR2 | 1.21014629 |
46 | CDC42BPA | 1.20725132 |
47 | MAP3K6 | 1.19206933 |
48 | RIPK1 | 1.17823897 |
49 | SMG1 | 1.17474195 |
50 | CLK1 | 1.16600680 |
51 | TLK1 | 1.16316587 |
52 | TYK2 | 1.15262129 |
53 | PBK | 1.06961743 |
54 | STK3 | 1.06926666 |
55 | NLK | 1.06596373 |
56 | TRPM7 | 1.05343353 |
57 | MAPK7 | 1.03906074 |
58 | CSK | 1.03663706 |
59 | ZAP70 | 1.01188104 |
60 | TEC | 1.01007527 |
61 | HCK | 1.00113167 |
62 | TAOK3 | 1.00112760 |
63 | CDK6 | 0.98283811 |
64 | CAMK1G | 0.96952410 |
65 | WNK1 | 0.95103769 |
66 | MTOR | 0.94737869 |
67 | BLK | 0.94154388 |
68 | SRPK1 | 0.93328647 |
69 | MAP3K2 | 0.92178501 |
70 | STK4 | 0.92157750 |
71 | INSRR | 0.92029314 |
72 | PKN2 | 0.89350639 |
73 | MAP3K1 | 0.87828124 |
74 | PKN1 | 0.87670248 |
75 | EPHB1 | 0.87178926 |
76 | RPS6KA4 | 0.85242898 |
77 | PRKAA2 | 0.84557601 |
78 | AKT3 | 0.84161425 |
79 | RET | 0.83955766 |
80 | FES | 0.83902656 |
81 | ERBB3 | 0.80592662 |
82 | MARK2 | 0.80195681 |
83 | MOS | 0.80176903 |
84 | MAP3K3 | 0.79339028 |
85 | PAK2 | 0.79227215 |
86 | FGFR2 | 0.77502091 |
87 | MAPK11 | 0.77328048 |
88 | IRAK2 | 0.73633889 |
89 | ERBB4 | 0.73054930 |
90 | MST1R | 0.72870302 |
91 | ABL1 | 0.71395064 |
92 | STK10 | 0.70644969 |
93 | JAK2 | 0.69734629 |
94 | CDK4 | 0.67828905 |
95 | PDGFRB | 0.67067089 |
96 | MAPK12 | 0.66405186 |
97 | SGK494 | 0.65651237 |
98 | SGK223 | 0.65651237 |
99 | STK24 | 0.65283122 |
100 | EPHB2 | 0.65002905 |
101 | SGK1 | 0.63964474 |
102 | LATS2 | 0.63855637 |
103 | MAP3K5 | 0.63148294 |
104 | SIK1 | 0.62114261 |
105 | SIK3 | 0.61553389 |
106 | SCYL2 | 0.60731726 |
107 | EIF2AK3 | 0.59953516 |
108 | IRAK1 | 0.59021791 |
109 | HIPK2 | 0.58207994 |
110 | NEK6 | 0.57601056 |
111 | ITK | 0.56885438 |
112 | FER | 0.56745541 |
113 | PDK1 | 0.56536741 |
114 | RPS6KB2 | 0.55335158 |
115 | MYLK | 0.54550172 |
116 | DDR2 | 0.53965401 |
117 | KIT | 0.53294897 |
118 | PDPK1 | 0.53244066 |
119 | LCK | 0.53221627 |
120 | GRK1 | 0.52708487 |
121 | DYRK1B | 0.51977230 |
122 | RAF1 | 0.51490781 |
123 | MARK3 | 0.51239454 |
124 | TGFBR2 | 0.50272846 |
125 | RPS6KB1 | 0.49879835 |
126 | RPS6KA5 | 0.49711405 |
127 | PRKD2 | 0.48138624 |
128 | TTN | 0.48038380 |
129 | DMPK | 0.47738021 |
130 | PIK3CA | 0.47593167 |
131 | CSF1R | 0.45773280 |
132 | BCR | 0.45648256 |
133 | RPS6KC1 | 0.45203311 |
134 | RPS6KL1 | 0.45203311 |
135 | MELK | 0.44893998 |
136 | CAMK1D | 0.44779320 |
137 | PRKCQ | 0.44490963 |
138 | AKT1 | 0.43079546 |
139 | LYN | 0.42867264 |
140 | RPS6KA2 | 0.41639855 |
141 | FLT3 | 0.41393472 |
142 | BTK | 0.37261197 |
143 | SYK | 0.37260931 |
144 | MAPK10 | 0.36217927 |
145 | CDK3 | 0.35968608 |
146 | FGR | 0.32719554 |
147 | CAMK4 | 0.32556460 |
148 | MAP3K7 | 0.30996567 |
149 | INSR | 0.30264027 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Phototransduction_Homo sapiens_hsa04744 | 2.82281394 |
2 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.59145954 |
3 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.46219486 |
4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.34860056 |
5 | Allograft rejection_Homo sapiens_hsa05330 | 2.12835367 |
6 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.10991588 |
7 | Leishmaniasis_Homo sapiens_hsa05140 | 2.03356749 |
8 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.91182278 |
9 | Measles_Homo sapiens_hsa05162 | 1.90972134 |
10 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.85382536 |
11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.83755175 |
12 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.78392420 |
13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.70874097 |
14 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.69962509 |
15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.65473583 |
16 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.64499033 |
17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.61522817 |
18 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.60676534 |
19 | Malaria_Homo sapiens_hsa05144 | 1.59029870 |
20 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.56980424 |
21 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.49793990 |
22 | Other glycan degradation_Homo sapiens_hsa00511 | 1.36797618 |
23 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.35778786 |
24 | Tuberculosis_Homo sapiens_hsa05152 | 1.35370969 |
25 | Influenza A_Homo sapiens_hsa05164 | 1.34171125 |
26 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.33824597 |
27 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.33083962 |
28 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.29467655 |
29 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.27268196 |
30 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.27096818 |
31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.26257785 |
32 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.26134201 |
33 | Prostate cancer_Homo sapiens_hsa05215 | 1.25128542 |
34 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.24368906 |
35 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.22582049 |
36 | Hepatitis B_Homo sapiens_hsa05161 | 1.20936394 |
37 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.17968566 |
38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.17201780 |
39 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.12982637 |
40 | Apoptosis_Homo sapiens_hsa04210 | 1.12373399 |
41 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.06686966 |
42 | Legionellosis_Homo sapiens_hsa05134 | 1.06023596 |
43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.05643007 |
44 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.05099142 |
45 | Viral myocarditis_Homo sapiens_hsa05416 | 1.04987494 |
46 | Asthma_Homo sapiens_hsa05310 | 1.03868696 |
47 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.02788625 |
48 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01606741 |
49 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.00844103 |
50 | Bladder cancer_Homo sapiens_hsa05219 | 0.99544387 |
51 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.98890200 |
52 | Salmonella infection_Homo sapiens_hsa05132 | 0.96853072 |
53 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.94895642 |
54 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.93287529 |
55 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.91863565 |
56 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.89812590 |
57 | Thyroid cancer_Homo sapiens_hsa05216 | 0.87805259 |
58 | Pertussis_Homo sapiens_hsa05133 | 0.87727931 |
59 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.86725397 |
60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.85895766 |
61 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.85110577 |
62 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.84142509 |
63 | Hepatitis C_Homo sapiens_hsa05160 | 0.83888579 |
64 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.82772217 |
65 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.81510663 |
66 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.81068869 |
67 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.80054088 |
68 | Amoebiasis_Homo sapiens_hsa05146 | 0.79332353 |
69 | Melanoma_Homo sapiens_hsa05218 | 0.78906447 |
70 | Adherens junction_Homo sapiens_hsa04520 | 0.78900095 |
71 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.77801328 |
72 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.77799225 |
73 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.77639853 |
74 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74423084 |
75 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.73040360 |
76 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.71898025 |
77 | Focal adhesion_Homo sapiens_hsa04510 | 0.71574168 |
78 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.71517142 |
79 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.71074814 |
80 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.70888917 |
81 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.70461070 |
82 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.68592207 |
83 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.68526541 |
84 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.68206283 |
85 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.67264668 |
86 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.67104599 |
87 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.66040706 |
88 | Platelet activation_Homo sapiens_hsa04611 | 0.65927595 |
89 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.65516198 |
90 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.65049581 |
91 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.63829200 |
92 | Pathways in cancer_Homo sapiens_hsa05200 | 0.62786536 |
93 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.62172375 |
94 | Shigellosis_Homo sapiens_hsa05131 | 0.61936167 |
95 | HTLV-I infection_Homo sapiens_hsa05166 | 0.61546043 |
96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.58999607 |
97 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.57440122 |
98 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.57074505 |
99 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.56643780 |
100 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.55372872 |
101 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.54375708 |
102 | Lysine degradation_Homo sapiens_hsa00310 | 0.54169353 |
103 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.52447614 |
104 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.52037864 |
105 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51871022 |
106 | Glioma_Homo sapiens_hsa05214 | 0.51266216 |
107 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.50902498 |
108 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.49946155 |
109 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.48441763 |
110 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.48427967 |
111 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.48023853 |
112 | Endometrial cancer_Homo sapiens_hsa05213 | 0.46490174 |
113 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.44264084 |
114 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.44033960 |
115 | Insulin resistance_Homo sapiens_hsa04931 | 0.42760085 |
116 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.40497056 |
117 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.39680236 |
118 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.38949701 |
119 | Colorectal cancer_Homo sapiens_hsa05210 | 0.38728923 |
120 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.38214695 |