RIDA

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)7.67727152
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.67727152
3L-phenylalanine metabolic process (GO:0006558)7.36285648
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.36285648
5aromatic amino acid family catabolic process (GO:0009074)6.94444848
6tryptophan catabolic process (GO:0006569)6.26707207
7indole-containing compound catabolic process (GO:0042436)6.26707207
8indolalkylamine catabolic process (GO:0046218)6.26707207
9glyoxylate metabolic process (GO:0046487)6.18574531
10kynurenine metabolic process (GO:0070189)5.95449036
11cysteine metabolic process (GO:0006534)5.94901317
12tryptophan metabolic process (GO:0006568)5.90427318
13bile acid biosynthetic process (GO:0006699)5.75370473
14triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.59571938
15epoxygenase P450 pathway (GO:0019373)5.50600428
16lysine metabolic process (GO:0006553)5.49212931
17lysine catabolic process (GO:0006554)5.49212931
18omega-hydroxylase P450 pathway (GO:0097267)5.40352945
19alpha-linolenic acid metabolic process (GO:0036109)5.30812701
20sulfur amino acid catabolic process (GO:0000098)5.30719871
21serine family amino acid catabolic process (GO:0009071)5.26116963
22urea cycle (GO:0000050)5.10538068
23urea metabolic process (GO:0019627)5.10538068
24fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.08640133
25aromatic amino acid family metabolic process (GO:0009072)5.05262756
26homocysteine metabolic process (GO:0050667)5.01037210
27high-density lipoprotein particle remodeling (GO:0034375)4.88983118
28bile acid metabolic process (GO:0008206)4.86999522
29negative regulation of fibrinolysis (GO:0051918)4.82938193
30amino-acid betaine metabolic process (GO:0006577)4.80064464
31alpha-amino acid catabolic process (GO:1901606)4.77424403
32protein carboxylation (GO:0018214)4.77055644
33peptidyl-glutamic acid carboxylation (GO:0017187)4.77055644
34nitrogen cycle metabolic process (GO:0071941)4.76085667
35tyrosine metabolic process (GO:0006570)4.66765093
36regulation of fibrinolysis (GO:0051917)4.66361028
37cellular ketone body metabolic process (GO:0046950)4.65797983
38drug transmembrane transport (GO:0006855)4.60540574
39complement activation, alternative pathway (GO:0006957)4.59470815
40urate metabolic process (GO:0046415)4.56234221
41mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.54084388
42regulation of protein activation cascade (GO:2000257)4.53884088
43serine family amino acid metabolic process (GO:0009069)4.53106770
44glutamate metabolic process (GO:0006536)4.48941346
45drug catabolic process (GO:0042737)4.48154894
46cellular amino acid catabolic process (GO:0009063)4.47154111
47indolalkylamine metabolic process (GO:0006586)4.44603316
48amine catabolic process (GO:0009310)4.39966277
49cellular biogenic amine catabolic process (GO:0042402)4.39966277
50regulation of cholesterol esterification (GO:0010872)4.39354178
51cellular modified amino acid catabolic process (GO:0042219)4.34398022
52L-serine metabolic process (GO:0006563)4.34344570
53coenzyme catabolic process (GO:0009109)4.33547314
54cellular glucuronidation (GO:0052695)4.33537538
55serine family amino acid biosynthetic process (GO:0009070)4.32980182
56short-chain fatty acid metabolic process (GO:0046459)4.30247202
57oxidative demethylation (GO:0070989)4.27480137
58negative regulation of sterol transport (GO:0032372)4.27352888
59negative regulation of cholesterol transport (GO:0032375)4.27352888
60glycine metabolic process (GO:0006544)4.26823617
61regulation of triglyceride catabolic process (GO:0010896)4.24694286
62benzene-containing compound metabolic process (GO:0042537)4.24624966
63aldehyde catabolic process (GO:0046185)4.24317035
64reverse cholesterol transport (GO:0043691)4.23949518
65regulation of complement activation (GO:0030449)4.23258449
66plasma lipoprotein particle remodeling (GO:0034369)4.22263753
67protein-lipid complex remodeling (GO:0034368)4.22263753
68macromolecular complex remodeling (GO:0034367)4.22263753
69triglyceride homeostasis (GO:0070328)4.14781132
70acylglycerol homeostasis (GO:0055090)4.14781132
71aspartate family amino acid catabolic process (GO:0009068)4.13086599
72ethanol oxidation (GO:0006069)4.11808687
73ketone body metabolic process (GO:1902224)4.03273660
74bile acid and bile salt transport (GO:0015721)4.02311158
75acetyl-CoA metabolic process (GO:0006084)4.01231055
76glucuronate metabolic process (GO:0019585)3.97774529
77uronic acid metabolic process (GO:0006063)3.97774529
78dicarboxylic acid biosynthetic process (GO:0043650)3.97269850
79phospholipid efflux (GO:0033700)3.97254421
80phenylpropanoid metabolic process (GO:0009698)3.96339844
81organic acid catabolic process (GO:0016054)3.95222760
82carboxylic acid catabolic process (GO:0046395)3.95222760
83blood coagulation, intrinsic pathway (GO:0007597)3.94638922
84exogenous drug catabolic process (GO:0042738)3.94428879
85imidazole-containing compound metabolic process (GO:0052803)3.90779477
86drug transport (GO:0015893)3.84998891
87arginine metabolic process (GO:0006525)3.82802704
88plasma lipoprotein particle clearance (GO:0034381)3.82309194
89energy coupled proton transport, down electrochemical gradient (GO:0015985)3.81179062
90ATP synthesis coupled proton transport (GO:0015986)3.81179062
91water-soluble vitamin biosynthetic process (GO:0042364)3.75732512
92fatty acid beta-oxidation (GO:0006635)3.71256258
932-oxoglutarate metabolic process (GO:0006103)3.71107325
94cofactor catabolic process (GO:0051187)3.70172441
95low-density lipoprotein particle remodeling (GO:0034374)3.69855217
96fatty acid oxidation (GO:0019395)3.69137267
97S-adenosylmethionine metabolic process (GO:0046500)3.68257193
98monocarboxylic acid catabolic process (GO:0072329)3.67547439
99cholesterol efflux (GO:0033344)3.66067960
100establishment of protein localization to mitochondrial membrane (GO:0090151)3.65561753
101carnitine metabolic process (GO:0009437)3.64177260
102lipid oxidation (GO:0034440)3.63502489
103chaperone-mediated protein transport (GO:0072321)3.63119168
104drug metabolic process (GO:0017144)3.60799242
105response to nitrosative stress (GO:0051409)3.60171941
106flavonoid metabolic process (GO:0009812)3.59861995
107regulation of bile acid biosynthetic process (GO:0070857)3.57970240
108response to mercury ion (GO:0046689)3.57467354
109fatty acid catabolic process (GO:0009062)3.54599255
110ethanol metabolic process (GO:0006067)3.53992138
111fibrinolysis (GO:0042730)3.53990806
112mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.50925103
113heme transport (GO:0015886)3.50177833
114plasma lipoprotein particle assembly (GO:0034377)3.49456242
115valine metabolic process (GO:0006573)3.49070138
116respiratory electron transport chain (GO:0022904)3.21790543
117regulation of plasminogen activation (GO:0010755)3.20537885
118L-methionine salvage (GO:0071267)3.18988050
119L-methionine biosynthetic process (GO:0071265)3.18988050
120amino acid salvage (GO:0043102)3.18988050
121proteasome assembly (GO:0043248)3.15428749
122electron transport chain (GO:0022900)3.12184865
123cellular aldehyde metabolic process (GO:0006081)2.98566588
124ribosomal small subunit assembly (GO:0000028)2.97098239
125daunorubicin metabolic process (GO:0044597)2.95748203
126polyketide metabolic process (GO:0030638)2.95748203
127doxorubicin metabolic process (GO:0044598)2.95748203
128branched-chain amino acid catabolic process (GO:0009083)2.94415897
129vitamin biosynthetic process (GO:0009110)2.93720623
130protein activation cascade (GO:0072376)2.80797925
131establishment of integrated proviral latency (GO:0075713)2.80780454
132tetrahydrofolate metabolic process (GO:0046653)2.78673232
133negative regulation of blood coagulation (GO:0030195)2.78098336
134negative regulation of hemostasis (GO:1900047)2.78098336
135xenobiotic catabolic process (GO:0042178)2.77432949
136regulation of mitochondrial translation (GO:0070129)2.77334467
137aminoglycoside antibiotic metabolic process (GO:0030647)2.72849020
138protein complex biogenesis (GO:0070271)2.69347986

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.22524604
2PPARA_22158963_ChIP-Seq_LIVER_Mouse6.99369063
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.79312781
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.31117920
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.04010290
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.88095436
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.87837724
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.40765341
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse4.00304821
10NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.79814459
11GABP_17652178_ChIP-ChIP_JURKAT_Human3.67886523
12EST1_17652178_ChIP-ChIP_JURKAT_Human3.24614584
13MYC_18555785_ChIP-Seq_MESCs_Mouse3.00881574
14E2F7_22180533_ChIP-Seq_HELA_Human2.82802381
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.68820905
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.39564111
17HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.39066941
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.24816218
19E2F4_17652178_ChIP-ChIP_JURKAT_Human2.24743655
20HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.20268700
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.17582073
22TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.11301484
23ELK1_19687146_ChIP-ChIP_HELA_Human2.10816892
24ETS1_20019798_ChIP-Seq_JURKAT_Human2.10126487
25TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.06868622
26ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.6486603
27AR_21909140_ChIP-Seq_LNCAP_Human1.88556034
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.86799357
29MYC_19030024_ChIP-ChIP_MESCs_Mouse1.85358937
30HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.83107831
31RBPJ_22232070_ChIP-Seq_NCS_Mouse1.82875128
32EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.78973443
33E2F1_18555785_ChIP-Seq_MESCs_Mouse1.78963987
34SRF_21415370_ChIP-Seq_HL-1_Mouse1.74678339
35MYC_19079543_ChIP-ChIP_MESCs_Mouse1.73903273
36POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.68878539
37NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.66980244
38SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.61488096
39CLOCK_20551151_ChIP-Seq_293T_Human1.59213344
40FOXA2_19822575_ChIP-Seq_HepG2_Human1.54700271
41VDR_23849224_ChIP-Seq_CD4+_Human1.53923289
42FUS_26573619_Chip-Seq_HEK293_Human1.51516342
43FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.50598593
44THAP11_20581084_ChIP-Seq_MESCs_Mouse1.49516750
45NELFA_20434984_ChIP-Seq_ESCs_Mouse1.49006135
46FOXP3_21729870_ChIP-Seq_TREG_Human1.48142001
47PADI4_21655091_ChIP-ChIP_MCF-7_Human1.46263279
48HTT_18923047_ChIP-ChIP_STHdh_Human1.45327923
49HNF4A_19822575_ChIP-Seq_HepG2_Human1.43069901
50MYC_18940864_ChIP-ChIP_HL60_Human1.42986876
51TTF2_22483619_ChIP-Seq_HELA_Human1.40326360
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.37976728
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37025611
54DCP1A_22483619_ChIP-Seq_HELA_Human1.35897511
55STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.33696528
56IGF1R_20145208_ChIP-Seq_DFB_Human1.33246992
57PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32831285
58VDR_22108803_ChIP-Seq_LS180_Human1.30191069
59EWS_26573619_Chip-Seq_HEK293_Human1.30031219
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.28235566
61FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.27744242
62XRN2_22483619_ChIP-Seq_HELA_Human1.25168783
63YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.22347386
64GATA1_22025678_ChIP-Seq_K562_Human1.21641374
65FLI1_27457419_Chip-Seq_LIVER_Mouse1.21229226
66NANOG_16153702_ChIP-ChIP_HESCs_Human1.20298701
67TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.16062865
68HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.15042761
69SOX2_16153702_ChIP-ChIP_HESCs_Human1.15000523
70MYCN_18555785_ChIP-Seq_MESCs_Mouse1.13863388
71ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.13818457
72SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13379400
73SALL1_21062744_ChIP-ChIP_HESCs_Human1.11535797
74RXRA_24833708_ChIP-Seq_LIVER_Mouse1.11277956
75GABP_19822575_ChIP-Seq_HepG2_Human1.10123638
76ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.08460136
77MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.07381175
78POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.07027963
79PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.06760200
80ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05306407
81PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.04254709
82P300_19829295_ChIP-Seq_ESCs_Human1.03205706
83SOX2_27498859_Chip-Seq_STOMACH_Mouse1.01478407
84RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.00720684
85GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.00687809
86E2F1_21310950_ChIP-Seq_MCF-7_Human0.98580308
87THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.98244156
88HOXB4_20404135_ChIP-ChIP_EML_Mouse0.96823423
89EZH2_27294783_Chip-Seq_NPCs_Mouse0.95294568
90IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.94798993
91PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.94469052
92NFE2_27457419_Chip-Seq_LIVER_Mouse0.94333643
93SOX17_20123909_ChIP-Seq_XEN_Mouse0.94315347
94CTBP1_25329375_ChIP-Seq_LNCAP_Human0.93976080
95CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93417135
96GATA4_25053715_ChIP-Seq_YYC3_Human0.92718358
97KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.91924252
98RARG_19884340_ChIP-ChIP_MEFs_Mouse0.91839051
99PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90333302
100ZFP57_27257070_Chip-Seq_ESCs_Mouse0.90254640
101MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.90077502
102ZNF274_21170338_ChIP-Seq_K562_Hela0.89067569
103E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.88521601
104YY1_21170310_ChIP-Seq_MESCs_Mouse0.88511484
105FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.87809168
106AUTS2_25519132_ChIP-Seq_293T-REX_Human0.86627125
107ELK1_22589737_ChIP-Seq_MCF10A_Human0.86593772
108ELF1_17652178_ChIP-ChIP_JURKAT_Human0.86540642
109TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86161693
110SUZ12_27294783_Chip-Seq_NPCs_Mouse0.85758084
111ZFX_18555785_ChIP-Seq_MESCs_Mouse0.84972062
112NANOG_19829295_ChIP-Seq_ESCs_Human0.84763470
113SOX2_19829295_ChIP-Seq_ESCs_Human0.84763470
114KAP1_22055183_ChIP-Seq_ESCs_Mouse0.83518562
115ESR1_15608294_ChIP-ChIP_MCF-7_Human0.81035726
116SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.78528807
117NRF2_20460467_ChIP-Seq_MEFs_Mouse0.78463800
118NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.78463800
119AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.77890444
120ESR2_21235772_ChIP-Seq_MCF-7_Human0.77501249
121BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.75589815
122SALL4_18804426_ChIP-ChIP_XEN_Mouse0.71816120
123RAD21_21589869_ChIP-Seq_MESCs_Mouse0.68733567
124NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.68544688
125BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.68419074
126ESR1_21235772_ChIP-Seq_MCF-7_Human0.68281869
127Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.65629122
128IRF8_22096565_ChIP-ChIP_GC-B_Human0.65475682
129ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.65435550
130SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.65194685
131AR_20517297_ChIP-Seq_VCAP_Human0.64586896
132EGR1_19032775_ChIP-ChIP_M12_Human0.63098105
133CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.61734198
134RARA_24833708_ChIP-Seq_LIVER_Mouse0.61299307
135TAF15_26573619_Chip-Seq_HEK293_Human0.61075745
136RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.60654603
137FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.59958424
138PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.59382791
139ZNF263_19887448_ChIP-Seq_K562_Human0.59297592
140NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.59179972
141MYC_19915707_ChIP-ChIP_AK7_Human0.58850037
142CEBPB_22108803_ChIP-Seq_LS180_Human0.58793072
143CDX2_20551321_ChIP-Seq_CACO-2_Human0.56650774
144ESET_19884257_ChIP-Seq_ESCs_Mouse0.55817948
145STAT3_1855785_ChIP-Seq_MESCs_Mouse0.55718684
146CBP_21632823_ChIP-Seq_H3396_Human0.55456923
147PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.53790577
148STAT1_17558387_ChIP-Seq_HELA_Human0.53667813
149RARB_24833708_ChIP-Seq_LIVER_Mouse0.53360909
150GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.53218938
151FOXA1_25552417_ChIP-Seq_VCAP_Human0.52952989
152STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.50989054
153PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.50925735
154PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.49055523
155TAF2_19829295_ChIP-Seq_ESCs_Human0.48562577
156PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.47342322
157EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.46561269
158P53_21459846_ChIP-Seq_SAOS-2_Human0.45508420
159ERG_21242973_ChIP-ChIP_JURKAT_Human0.45296600
160IRF1_19129219_ChIP-ChIP_H3396_Human0.44688473
161FOXO3_23340844_ChIP-Seq_DLD1_Human0.44612340
162SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.43602796
163FOXH1_21741376_ChIP-Seq_EPCs_Human0.43477685
164CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.43300482
165CDX2_22108803_ChIP-Seq_LS180_Human0.43248833
166NCOR_22424771_ChIP-Seq_293T_Human0.43075405
167FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.42726809
168ERG_20517297_ChIP-Seq_VCAP_Human0.42654016
169LXR_22292898_ChIP-Seq_THP-1_Human0.42390675
170SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.41972522
171SOX2_20726797_ChIP-Seq_SW620_Human0.41705607
172FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.40639192
173PPAR_26484153_Chip-Seq_NCI-H1993_Human0.40437542
174BCAT_22108803_ChIP-Seq_LS180_Human0.40320036
175SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.40035172
176P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.39479100
177GATA6_25053715_ChIP-Seq_YYC3_Human0.39329934
178NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.38985845
179PIAS1_25552417_ChIP-Seq_VCAP_Human0.38616227
180SOX2_22085726_ChIP-Seq_NPCs_Mouse0.38452139
181GATA1_19941826_ChIP-Seq_K562_Human0.38154777

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.19808733
2MP0005360_urolithiasis7.94039018
3MP0005085_abnormal_gallbladder_physiolo6.02124004
4MP0005365_abnormal_bile_salt5.86649717
5MP0008875_abnormal_xenobiotic_pharmacok5.11396156
6MP0003806_abnormal_nucleotide_metabolis4.28203519
7MP0003252_abnormal_bile_duct3.76906522
8MP0003195_calcinosis3.39262586
9MP0005332_abnormal_amino_acid3.37401641
10MP0010329_abnormal_lipoprotein_level3.23981290
11MP0009840_abnormal_foam_cell2.81082466
12MP0005083_abnormal_biliary_tract2.73128955
13MP0004019_abnormal_vitamin_homeostasis2.72837579
14MP0006292_abnormal_olfactory_placode2.57921208
15MP0001666_abnormal_nutrient_absorption2.47760371
16MP0002138_abnormal_hepatobiliary_system2.32775775
17MP0003191_abnormal_cellular_cholesterol2.08084248
18MP0009379_abnormal_foot_pigmentation2.06625802
19MP0003136_yellow_coat_color2.02911741
20MP0002118_abnormal_lipid_homeostasis2.02385538
21MP0003941_abnormal_skin_development1.98853647
22MP0000609_abnormal_liver_physiology1.95213183
23MP0005319_abnormal_enzyme/_coenzyme1.83148636
24MP0009643_abnormal_urine_homeostasis1.78931821
25MP0008058_abnormal_DNA_repair1.78289057
26MP0002938_white_spotting1.76607965
27MP0001764_abnormal_homeostasis1.76190893
28MP0005584_abnormal_enzyme/coenzyme_acti1.71272461
29MP0003868_abnormal_feces_composition1.66962601
30MP0003186_abnormal_redox_activity1.65772502
31MP0001529_abnormal_vocalization1.62016348
32MP0005451_abnormal_body_composition1.55205562
33MP0001293_anophthalmia1.52562235
34MP0000566_synostosis1.52487446
35MP0004043_abnormal_pH_regulation1.41748400
36MP0004957_abnormal_blastocyst_morpholog1.41335760
37MP0005636_abnormal_mineral_homeostasis1.41156116
38MP0010094_abnormal_chromosome_stability1.35297267
39MP0009697_abnormal_copulation1.33632318
40MP0003693_abnormal_embryo_hatching1.27574937
41MP0005187_abnormal_penis_morphology1.25755357
42MP0003011_delayed_dark_adaptation1.18222539
43MP0003880_abnormal_central_pattern1.13394898
44MP0003656_abnormal_erythrocyte_physiolo1.13296362
45MP0002090_abnormal_vision1.11927912
46MP0006036_abnormal_mitochondrial_physio1.08509219
47MP0008789_abnormal_olfactory_epithelium1.07539453
48MP0000598_abnormal_liver_morphology1.06684776
49MP0008932_abnormal_embryonic_tissue1.06559885
50MP0010030_abnormal_orbit_morphology1.06169666
51MP0002282_abnormal_trachea_morphology1.05890023
52MP0001756_abnormal_urination1.04959136
53MP0009764_decreased_sensitivity_to1.02361207
54MP0000604_amyloidosis1.02298424
55MP0005647_abnormal_sex_gland1.01710007
56MP0005084_abnormal_gallbladder_morpholo0.97224754
57MP0003077_abnormal_cell_cycle0.96713473
58MP0001485_abnormal_pinna_reflex0.95767863
59MP0002876_abnormal_thyroid_physiology0.95497514
60MP0002233_abnormal_nose_morphology0.92566019
61MP0002697_abnormal_eye_size0.91226477
62MP0005408_hypopigmentation0.91053296
63MP0000372_irregular_coat_pigmentation0.90517056
64MP0002136_abnormal_kidney_physiology0.89937353
65MP0003567_abnormal_fetal_cardiomyocyte0.89607829
66MP0009763_increased_sensitivity_to0.88416987
67MP0009642_abnormal_blood_homeostasis0.88210090
68MP0002736_abnormal_nociception_after0.87452483
69MP0003111_abnormal_nucleus_morphology0.85914081
70MP0008469_abnormal_protein_level0.85704696
71MP0006072_abnormal_retinal_apoptosis0.83460533
72MP0004142_abnormal_muscle_tone0.80291340
73MP0005535_abnormal_body_temperature0.79839903
74MP0005376_homeostasis/metabolism_phenot0.79674557
75MP0002234_abnormal_pharynx_morphology0.79479205
76MP0003690_abnormal_glial_cell0.79393872
77MP0001765_abnormal_ion_homeostasis0.78706595
78MP0002254_reproductive_system_inflammat0.77418478
79MP0005670_abnormal_white_adipose0.76963371
80MP0003329_amyloid_beta_deposits0.76671949
81MP0009765_abnormal_xenobiotic_induced0.76240435
82MP0005220_abnormal_exocrine_pancreas0.74462609
83MP0001661_extended_life_span0.73960251
84MP0003890_abnormal_embryonic-extraembry0.73700913
85MP0002132_abnormal_respiratory_system0.73650928
86MP0002078_abnormal_glucose_homeostasis0.73387561
87MP0003937_abnormal_limbs/digits/tail_de0.72934735
88MP0008007_abnormal_cellular_replicative0.72674830
89MP0005551_abnormal_eye_electrophysiolog0.71840809
90MP0003705_abnormal_hypodermis_morpholog0.69150757
91MP0006035_abnormal_mitochondrial_morpho0.67624222
92MP0001984_abnormal_olfaction0.65000027
93MP0002102_abnormal_ear_morphology0.64042267
94MP0001286_abnormal_eye_development0.63131814
95MP0005266_abnormal_metabolism0.62844770
96MP0002971_abnormal_brown_adipose0.61920728
97MP0002638_abnormal_pupillary_reflex0.61029606
98MP0003938_abnormal_ear_development0.60944456
99MP0005058_abnormal_lysosome_morphology0.60762863
100MP0000631_abnormal_neuroendocrine_gland0.60649785
101MP0010368_abnormal_lymphatic_system0.59734560
102MP0003119_abnormal_digestive_system0.59396298
103MP0004133_heterotaxia0.59255804
104MP0005646_abnormal_pituitary_gland0.59221541
105MP0003638_abnormal_response/metabolism_0.59194284
106MP0003786_premature_aging0.59112795
107MP0003283_abnormal_digestive_organ0.58330520
108MP0000049_abnormal_middle_ear0.58077433
109MP0003122_maternal_imprinting0.58066291
110MP0005334_abnormal_fat_pad0.57327928
111MP0005394_taste/olfaction_phenotype0.56582173
112MP0005499_abnormal_olfactory_system0.56582173
113MP0006276_abnormal_autonomic_nervous0.55991262
114MP0005395_other_phenotype0.55419402
115MP0002928_abnormal_bile_duct0.54806918
116MP0005253_abnormal_eye_physiology0.52788524
117MP0002751_abnormal_autonomic_nervous0.52484940
118MP0005379_endocrine/exocrine_gland_phen0.51780206
119MP0005391_vision/eye_phenotype0.51645735
120MP0001324_abnormal_eye_pigmentation0.51558096
121MP0000230_abnormal_systemic_arterial0.51350116
122MP0003315_abnormal_perineum_morphology0.50749728
123MP0002249_abnormal_larynx_morphology0.49906436
124MP0000639_abnormal_adrenal_gland0.47646730
125MP0004130_abnormal_muscle_cell0.47563452
126MP0003718_maternal_effect0.46940026
127MP0002168_other_aberrant_phenotype0.45109867
128MP0008872_abnormal_physiological_respon0.45059417
129MP0003075_altered_response_to0.44625174
130MP0008874_decreased_physiological_sensi0.44110021
131MP0009053_abnormal_anal_canal0.42388409
132MP0008873_increased_physiological_sensi0.42308361
133MP0003953_abnormal_hormone_level0.41621878
134MP0002822_catalepsy0.40212476
135MP0005448_abnormal_energy_balance0.40160079
136MP0005666_abnormal_adipose_tissue0.38340184
137MP0000538_abnormal_urinary_bladder0.37993286
138MP0003724_increased_susceptibility_to0.37289823
139MP0005166_decreased_susceptibility_to0.37106725
140MP0002796_impaired_skin_barrier0.35530327
141MP0004147_increased_porphyrin_level0.33995731
142MP0002135_abnormal_kidney_morphology0.33907404
143MP0004782_abnormal_surfactant_physiolog0.33809585
144MP0005464_abnormal_platelet_physiology0.33122549
145MP0006082_CNS_inflammation0.31060959
146MP0009672_abnormal_birth_weight0.30135053
147MP0002837_dystrophic_cardiac_calcinosis0.28583863
148MP0009384_cardiac_valve_regurgitation0.25932837
149MP0003959_abnormal_lean_body0.25486470
150MP0005595_abnormal_vascular_smooth0.24198080
151MP0001845_abnormal_inflammatory_respons0.23374673
152MP0004264_abnormal_extraembryonic_tissu0.23301591
153MP0005248_abnormal_Harderian_gland0.22962482
154MP0009115_abnormal_fat_cell0.22751925
155MP0005167_abnormal_blood-brain_barrier0.20956568
156MP0000249_abnormal_blood_vessel0.20719286
157MP0002295_abnormal_pulmonary_circulatio0.20652024
158MP0003633_abnormal_nervous_system0.20308233

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.14629277
2Intrahepatic cholestasis (HP:0001406)6.58998045
3Deep venous thrombosis (HP:0002625)6.28537547
4Abnormality of monocarboxylic acid metabolism (HP:0010996)5.96139250
5Xanthomatosis (HP:0000991)5.70888097
6Hypobetalipoproteinemia (HP:0003563)5.56700123
7Prolonged partial thromboplastin time (HP:0003645)5.50583638
8Hyperlipoproteinemia (HP:0010980)4.93279753
9Hyperglycinuria (HP:0003108)4.68878556
10Abnormality of glutamine family amino acid metabolism (HP:0010902)4.67644080
11Hyperammonemia (HP:0001987)4.61869171
12Hyperglycinemia (HP:0002154)4.59159888
13Ketosis (HP:0001946)4.50990703
14Abnormality of serine family amino acid metabolism (HP:0010894)4.50779241
15Abnormality of glycine metabolism (HP:0010895)4.50779241
16Abnormality of aspartate family amino acid metabolism (HP:0010899)4.43733826
17Complement deficiency (HP:0004431)4.32855205
18Abnormality of sulfur amino acid metabolism (HP:0004339)4.25907524
19Joint hemorrhage (HP:0005261)4.13728565
20Hypolipoproteinemia (HP:0010981)4.04409718
21Acute encephalopathy (HP:0006846)3.98430220
22Abnormality of methionine metabolism (HP:0010901)3.98034611
23Epidermoid cyst (HP:0200040)3.84586603
24Gout (HP:0001997)3.83586206
25Fat malabsorption (HP:0002630)3.82643776
26Acute necrotizing encephalopathy (HP:0006965)3.81349412
27Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.73662671
28Abnormality of fatty-acid metabolism (HP:0004359)3.72951377
29Abnormality of the common coagulation pathway (HP:0010990)3.70897899
30Hypoglycemic coma (HP:0001325)3.69573690
31Ketoacidosis (HP:0001993)3.60189043
32Delayed CNS myelination (HP:0002188)3.51791803
33Abnormality of pyrimidine metabolism (HP:0004353)3.44974602
34Hypoalphalipoproteinemia (HP:0003233)3.42495511
35Abnormality of nucleobase metabolism (HP:0010932)3.41385900
36Abnormality of purine metabolism (HP:0004352)3.39591549
37Abnormal mitochondria in muscle tissue (HP:0008316)3.37288730
38Conjugated hyperbilirubinemia (HP:0002908)3.33044763
39Mitochondrial inheritance (HP:0001427)3.24572968
40Increased hepatocellular lipid droplets (HP:0006565)3.22685198
41Increased serum pyruvate (HP:0003542)3.20565331
42Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.19619723
43Abnormality of serum amino acid levels (HP:0003112)3.19043274
44Progressive macrocephaly (HP:0004481)3.18505544
45Reduced antithrombin III activity (HP:0001976)3.18468379
46Lipid accumulation in hepatocytes (HP:0006561)3.16469601
47Abnormality of the intrinsic pathway (HP:0010989)3.15331189
48Hyperbilirubinemia (HP:0002904)3.13194438
49Metabolic acidosis (HP:0001942)3.08324437
50Hypercholesterolemia (HP:0003124)3.06404096
51Abnormality of complement system (HP:0005339)3.04410337
52Increased CSF lactate (HP:0002490)3.02571370
53Steatorrhea (HP:0002570)2.97333866
54Dicarboxylic aciduria (HP:0003215)2.96226385
55Abnormality of dicarboxylic acid metabolism (HP:0010995)2.96226385
56Lethargy (HP:0001254)2.95603454
57Vascular calcification (HP:0004934)2.93304747
58Alkalosis (HP:0001948)2.90155030
59Proximal tubulopathy (HP:0000114)2.87874449
60Generalized aminoaciduria (HP:0002909)2.87851375
61Abnormality of glycolysis (HP:0004366)2.87454985
62Hepatocellular carcinoma (HP:0001402)2.77726680
63Hepatic necrosis (HP:0002605)2.77620932
64Cerebral edema (HP:0002181)2.71603562
65Increased purine levels (HP:0004368)2.71256538
66Hyperuricemia (HP:0002149)2.71256538
67Hepatocellular necrosis (HP:0001404)2.70308829
68Renal Fanconi syndrome (HP:0001994)2.68644777
69Cardiovascular calcification (HP:0011915)2.57455359
70Colon cancer (HP:0003003)2.54358316
71Irritability (HP:0000737)2.52724725
72Malnutrition (HP:0004395)2.51563370
73Vomiting (HP:0002013)2.49191096
74Macrocytic anemia (HP:0001972)2.46722973
75Glycosuria (HP:0003076)2.46579642
76Abnormality of urine glucose concentration (HP:0011016)2.46579642
77Spastic diplegia (HP:0001264)2.46091980
78Spontaneous abortion (HP:0005268)2.44455770
79Enlarged kidneys (HP:0000105)2.42694296
80Myocardial infarction (HP:0001658)2.35861153
81Neonatal onset (HP:0003623)2.35742041
82Rickets (HP:0002748)2.34715707
83Increased serum lactate (HP:0002151)2.32771160
84Hypochromic microcytic anemia (HP:0004840)2.32184892
85Methylmalonic acidemia (HP:0002912)2.28406061
86Skin nodule (HP:0200036)2.27942839
87Abnormality of proline metabolism (HP:0010907)2.26574041
88Hydroxyprolinuria (HP:0003080)2.26574041
89Systemic lupus erythematosus (HP:0002725)2.25787935
90Sensorimotor neuropathy (HP:0007141)2.25515862
91Lactic acidosis (HP:0003128)2.22898379
92Abnormality of the labia minora (HP:0012880)2.21503803
93Hypoglycemic seizures (HP:0002173)2.21405750
94Late onset (HP:0003584)2.16529370
95Hypokalemic alkalosis (HP:0001949)2.15112233
96Leukodystrophy (HP:0002415)2.14436652
97Abnormal gallbladder morphology (HP:0012437)2.14405166
98Opisthotonus (HP:0002179)2.13157040
99Septo-optic dysplasia (HP:0100842)2.12935246
100Cholecystitis (HP:0001082)2.12585488
101Abnormal gallbladder physiology (HP:0012438)2.12585488
102Abnormal urine phosphate concentration (HP:0012599)2.11897820
103Abnormality of alanine metabolism (HP:0010916)2.11629146
104Hyperalaninemia (HP:0003348)2.11629146
105Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.11629146
106Pancreatitis (HP:0001733)2.11312499
107Mitral stenosis (HP:0001718)2.10506108
108Megaloblastic anemia (HP:0001889)2.10380334
109Hypophosphatemic rickets (HP:0004912)2.07591936
110Cholelithiasis (HP:0001081)2.06752556
111Abnormal enzyme/coenzyme activity (HP:0012379)2.05495273
112Brushfield spots (HP:0001088)2.05488815
113Acanthocytosis (HP:0001927)2.04978788
114Hyperinsulinemic hypoglycemia (HP:0000825)2.04674859
115Reticulocytopenia (HP:0001896)2.01243670
116Confusion (HP:0001289)1.99661262
117Glomerulonephritis (HP:0000099)1.98483167
118CNS demyelination (HP:0007305)1.98125909
119Respiratory failure (HP:0002878)1.95918086
120Increased intramyocellular lipid droplets (HP:0012240)1.95714230
1213-Methylglutaconic aciduria (HP:0003535)1.92945730
122Abnormality of vitamin metabolism (HP:0100508)1.89891423
123Amyloidosis (HP:0011034)1.89269106
124Renal cortical cysts (HP:0000803)1.88950468
125Increased circulating renin level (HP:0000848)1.88821985
126Nephrolithiasis (HP:0000787)1.88234337
127Esophageal varix (HP:0002040)1.85277431
128Methylmalonic aciduria (HP:0012120)1.84848034
129Type I transferrin isoform profile (HP:0003642)1.84473688
130Abnormal cartilage morphology (HP:0002763)1.82135986
131Abnormality of alkaline phosphatase activity (HP:0004379)1.81727912
132Thrombophlebitis (HP:0004418)1.80918964
133Hyperphosphaturia (HP:0003109)1.80800769
134Metabolic alkalosis (HP:0200114)1.79447262
135Exercise intolerance (HP:0003546)1.79198057
136Abnormality of the gallbladder (HP:0005264)1.78569898
137Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.77284387
138Decreased activity of mitochondrial respiratory chain (HP:0008972)1.77284387
139Exertional dyspnea (HP:0002875)1.71545931
140Abnormal biliary tract physiology (HP:0012439)1.70157714
141Bile duct proliferation (HP:0001408)1.70157714
142Increased muscle lipid content (HP:0009058)1.69189117
143Optic disc pallor (HP:0000543)1.68645379
144Degeneration of anterior horn cells (HP:0002398)1.66897729
145Abnormality of the anterior horn cell (HP:0006802)1.66897729

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.79888967
2FGFR44.01552186
3VRK23.89021418
4SIK13.53980475
5WNK33.45923276
6WNK43.45696268
7OXSR13.35670467
8ERN13.33932973
9BUB13.29167460
10CDC72.65343245
11INSRR2.62651770
12ERBB42.53757642
13ZAK2.53555087
14TAOK32.32330899
15VRK12.28237163
16SRPK12.24854705
17MST42.23695815
18TSSK62.17389183
19MST1R2.12017437
20PLK32.06360978
21TTK2.00391340
22TNIK1.98536169
23MAP2K41.93799149
24EIF2AK11.92700744
25NUAK11.87007655
26MKNK21.86789417
27BMPR1B1.85434065
28STK391.84392177
29WEE11.82544609
30MKNK11.79252496
31TRIM281.77252221
32EIF2AK31.75604396
33PINK11.70988664
34TAF11.69447469
35PLK41.67858030
36PIK3CG1.67509640
37MAP4K21.66636595
38STK38L1.64979698
39MAPK111.61182828
40ABL21.59397528
41MAP3K121.56736569
42BRSK21.53422225
43NME11.37087528
44FLT31.35154314
45DAPK21.32448743
46EPHB11.29659940
47TYK21.27623697
48CASK1.27445422
49PKN21.27192029
50FRK1.26722064
51PLK11.25852633
52SGK4941.23514148
53SGK2231.23514148
54FGFR21.23437064
55PNCK1.23019856
56DYRK21.15648392
57GRK61.13567925
58NEK91.09758232
59PBK1.09323683
60MAP3K71.06871914
61KDR1.02102449
62LATS11.00704826
63PRKAA20.99651839
64PTK60.99614093
65MET0.98405700
66JAK20.96152973
67NME20.93869832
68MAPK150.92926371
69PDK30.92782947
70PDK40.92782947
71BRSK10.92234812
72MAPK40.91534462
73MUSK0.90000100
74PRKCZ0.87179853
75BCR0.87086134
76GSK3A0.86905100
77TRIB30.86830460
78TIE10.82490604
79PLK20.79055853
80PASK0.79048707
81MAPK120.78816060
82EIF2AK20.78473849
83STK240.77178029
84SGK30.77130983
85MAP3K30.77111186
86CAMK2G0.77074661
87ERBB30.77005024
88MAP3K140.76712680
89AURKB0.75921579
90PRKACG0.72918893
91SGK20.72200303
92ERBB20.71977826
93MAP2K70.70085439
94CSNK2A10.69217524
95CDK80.69170357
96CSNK2A20.68624636
97DYRK30.68517100
98EPHA40.68317042
99MAP2K30.68200848
100DYRK1B0.63079583
101PRKAA10.61486618
102IRAK30.60813886
103CSNK1G10.60732917
104CHEK20.60517293
105ATR0.59926788
106TBK10.59766627
107MAP3K40.58944452
108MAP3K110.58582580
109MAP2K60.58340996
110TGFBR20.58217301
111JAK10.57742561
112PDPK10.57591544
113PRKCQ0.56877724
114CCNB10.56097679
115CDK30.55421707
116PDK20.54248938
117CSNK1E0.54235774
118NEK10.50970658
119ACVR1B0.50642845
120STK30.50464101
121TGFBR10.49239312
122FGFR10.49206149
123GRK10.47587823
124PTK20.46412979
125ATM0.46262189
126AURKA0.44709424
127CSNK1G30.43060286
128PRKCG0.41982972
129CDK60.41283467
130OBSCN0.40686935
131MAPK70.40447056
132PKN10.40362359
133IGF1R0.40156643
134STK40.40046891
135CSK0.39747752
136CDK190.39301071
137STK160.38965446
138PRKCE0.38850727
139CSNK1G20.38845999
140ALK0.37141913
141CSNK1A10.36473139
142MINK10.36405668
143UHMK10.34656352
144PRKCA0.34579619
145IRAK20.34256338
146PIK3CA0.34239648
147PDK10.33841788
148TLK10.33695197
149PRKDC0.33203193
150ADRBK20.33184816
151NTRK30.32624396
152DAPK30.31950677
153CSF1R0.31896963
154EPHA30.31870360
155IRAK10.31216628
156RPS6KA40.29704405
157DAPK10.29053109
158IKBKE0.28747177
159PRKACA0.28549109
160PAK40.28227477
161CSNK1A1L0.26534834
162MAP2K10.25974629
163PAK30.25597663
164STK380.24573250
165MYLK0.24142751
166EGFR0.22225695
167PRKACB0.22076624
168MAP3K130.20485186
169ABL10.19995732
170MAP2K20.19863590
171PRKCD0.18874641
172CAMK40.16712651
173RET0.15798610

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.06137271
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.41315643
3Nitrogen metabolism_Homo sapiens_hsa009103.27838760
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.07025756
5Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.79285938
6Arginine biosynthesis_Homo sapiens_hsa002202.78589980
7Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.73793755
8Tryptophan metabolism_Homo sapiens_hsa003802.65751818
9Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.63212236
10Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.58116265
11Fatty acid degradation_Homo sapiens_hsa000712.51431094
12Butanoate metabolism_Homo sapiens_hsa006502.47917644
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.42027775
14Complement and coagulation cascades_Homo sapiens_hsa046102.26646873
15Peroxisome_Homo sapiens_hsa041462.26165072
16Propanoate metabolism_Homo sapiens_hsa006402.25229546
17Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.14774490
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.12056956
19Proteasome_Homo sapiens_hsa030501.95273286
20Chemical carcinogenesis_Homo sapiens_hsa052041.91267695
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.90159236
22Histidine metabolism_Homo sapiens_hsa003401.89049030
23Fatty acid metabolism_Homo sapiens_hsa012121.87204575
24Ribosome_Homo sapiens_hsa030101.83505952
25Steroid hormone biosynthesis_Homo sapiens_hsa001401.82410613
26beta-Alanine metabolism_Homo sapiens_hsa004101.79231403
27PPAR signaling pathway_Homo sapiens_hsa033201.77532666
282-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.74043565
29Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.67927624
30Drug metabolism - other enzymes_Homo sapiens_hsa009831.65484812
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.64892097
32Pyruvate metabolism_Homo sapiens_hsa006201.60889494
33Retinol metabolism_Homo sapiens_hsa008301.59603626
34Sulfur metabolism_Homo sapiens_hsa009201.55734052
35Bile secretion_Homo sapiens_hsa049761.52335040
36Fatty acid elongation_Homo sapiens_hsa000621.50695408
37Selenocompound metabolism_Homo sapiens_hsa004501.48756517
38Phenylalanine metabolism_Homo sapiens_hsa003601.47990592
39Caffeine metabolism_Homo sapiens_hsa002321.47490853
40Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.43479891
41Cyanoamino acid metabolism_Homo sapiens_hsa004601.41605680
42Protein export_Homo sapiens_hsa030601.36759532
43Staphylococcus aureus infection_Homo sapiens_hsa051501.33761578
44Steroid biosynthesis_Homo sapiens_hsa001001.33072323
45Tyrosine metabolism_Homo sapiens_hsa003501.32454902
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.31363370
47Folate biosynthesis_Homo sapiens_hsa007901.29173694
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26191490
49Mismatch repair_Homo sapiens_hsa034301.25966817
50Starch and sucrose metabolism_Homo sapiens_hsa005001.25574593
51Carbon metabolism_Homo sapiens_hsa012001.24154245
52Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.23610795
53Biosynthesis of amino acids_Homo sapiens_hsa012301.21018802
54RNA polymerase_Homo sapiens_hsa030201.12570979
55Arginine and proline metabolism_Homo sapiens_hsa003301.11645364
56Huntingtons disease_Homo sapiens_hsa050161.10759427
57Vitamin digestion and absorption_Homo sapiens_hsa049771.09031897
58DNA replication_Homo sapiens_hsa030301.08393434
59ABC transporters_Homo sapiens_hsa020101.06066587
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.95557890
61Fat digestion and absorption_Homo sapiens_hsa049750.94338133
62Glutathione metabolism_Homo sapiens_hsa004800.93807283
63Maturity onset diabetes of the young_Homo sapiens_hsa049500.92548053
64Sulfur relay system_Homo sapiens_hsa041220.89463811
65Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.85505829
66Vitamin B6 metabolism_Homo sapiens_hsa007500.84058824
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80838680
68Lysine degradation_Homo sapiens_hsa003100.80514677
69Homologous recombination_Homo sapiens_hsa034400.79871022
70Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.79532960
71Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.77697515
72Glycerolipid metabolism_Homo sapiens_hsa005610.71897115
73Spliceosome_Homo sapiens_hsa030400.71357964
74Pyrimidine metabolism_Homo sapiens_hsa002400.66772121
75Non-homologous end-joining_Homo sapiens_hsa034500.64909730
76Base excision repair_Homo sapiens_hsa034100.63905124
77One carbon pool by folate_Homo sapiens_hsa006700.62488970
78Nucleotide excision repair_Homo sapiens_hsa034200.62199622
79RNA degradation_Homo sapiens_hsa030180.59867059
80Pentose phosphate pathway_Homo sapiens_hsa000300.59407973
81Metabolic pathways_Homo sapiens_hsa011000.54698389
82RNA transport_Homo sapiens_hsa030130.53133180
83Fanconi anemia pathway_Homo sapiens_hsa034600.52789544
84Cardiac muscle contraction_Homo sapiens_hsa042600.52317074
85Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.51166698
86Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.49611337
87Basal transcription factors_Homo sapiens_hsa030220.49014342
88Fatty acid biosynthesis_Homo sapiens_hsa000610.41419988
89Purine metabolism_Homo sapiens_hsa002300.38839808
90Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.36808232
91Fructose and mannose metabolism_Homo sapiens_hsa000510.34548736
92alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.29608388
93Cell cycle_Homo sapiens_hsa041100.24550973
94Galactose metabolism_Homo sapiens_hsa000520.22130002
95Linoleic acid metabolism_Homo sapiens_hsa005910.21646761
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.20355772
97Prion diseases_Homo sapiens_hsa050200.16655814
98Systemic lupus erythematosus_Homo sapiens_hsa053220.15256126
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.12628226
100Insulin resistance_Homo sapiens_hsa049310.10930029
101Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.10381229
102Glycerophospholipid metabolism_Homo sapiens_hsa005640.10359194
103Basal cell carcinoma_Homo sapiens_hsa052170.04139485
104Collecting duct acid secretion_Homo sapiens_hsa04966-0.2082163
105Hepatitis C_Homo sapiens_hsa05160-0.2049019
106Insulin signaling pathway_Homo sapiens_hsa04910-0.2023468
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1939890
108Alzheimers disease_Homo sapiens_hsa05010-0.1750453
109Lysosome_Homo sapiens_hsa04142-0.1708539
110Other glycan degradation_Homo sapiens_hsa00511-0.1500094
111Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1461261
112Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.1379521
113Ether lipid metabolism_Homo sapiens_hsa00565-0.1193946
114Parkinsons disease_Homo sapiens_hsa05012-0.1177357
115Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1116340
116Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1078265
117Protein digestion and absorption_Homo sapiens_hsa04974-0.1028616
118Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0939548
119Regulation of autophagy_Homo sapiens_hsa04140-0.0891208
120Mineral absorption_Homo sapiens_hsa04978-0.0711529
121Renin-angiotensin system_Homo sapiens_hsa04614-0.0602401
122AMPK signaling pathway_Homo sapiens_hsa04152-0.0560597
123Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0160943
124Oxidative phosphorylation_Homo sapiens_hsa00190-0.0107568
125Glucagon signaling pathway_Homo sapiens_hsa04922-0.0048151

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