RIIAD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1GTP biosynthetic process (GO:0006183)9.22034172
2nucleoside diphosphate phosphorylation (GO:0006165)8.57249451
3UTP biosynthetic process (GO:0006228)8.19181538
4ventricular system development (GO:0021591)7.82843181
5UTP metabolic process (GO:0046051)7.42508244
6intraciliary transport (GO:0042073)6.78192404
7guanosine-containing compound biosynthetic process (GO:1901070)6.31202737
8motile cilium assembly (GO:0044458)6.19755303
9left/right axis specification (GO:0070986)6.13305418
10CTP metabolic process (GO:0046036)6.01303150
11CTP biosynthetic process (GO:0006241)6.01303150
12regulation of female gonad development (GO:2000194)5.96091186
13regulation of DNA methylation (GO:0044030)5.78203316
14piRNA metabolic process (GO:0034587)5.60182679
15pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)5.47259953
16cilium organization (GO:0044782)5.45468894
17retinal cone cell development (GO:0046549)5.34473724
18positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.18348558
19cilium assembly (GO:0042384)5.16771652
20pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)5.06750082
21regulation of cilium movement (GO:0003352)5.04096269
22regulation of acrosome reaction (GO:0060046)4.88001505
23meiotic cell cycle (GO:0051321)4.73309507
24nucleotide phosphorylation (GO:0046939)4.68947489
25pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)4.57660795
26microtubule bundle formation (GO:0001578)4.53692004
27regulation of meiosis I (GO:0060631)4.53335298
28cilium morphogenesis (GO:0060271)4.50921591
29DNA methylation involved in gamete generation (GO:0043046)4.46448517
30negative regulation of retinoic acid receptor signaling pathway (GO:0048387)4.39416555
31positive regulation of histone H3-K4 methylation (GO:0051571)4.39017308
32cellular component assembly involved in morphogenesis (GO:0010927)4.31963273
33nucleoside diphosphate metabolic process (GO:0009132)4.25532016
34sperm motility (GO:0030317)4.22967294
35glycine transport (GO:0015816)4.18334113
36acrosome reaction (GO:0007340)4.00381448
37pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.91406459
38oocyte development (GO:0048599)3.90868433
39purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.87720462
40regulation of retinoic acid receptor signaling pathway (GO:0048385)3.80079707
41microtubule-based movement (GO:0007018)3.80025114
42oxygen transport (GO:0015671)3.79419345
43protein localization to cilium (GO:0061512)3.78170291
44purine nucleoside triphosphate biosynthetic process (GO:0009145)3.76054066
45nonmotile primary cilium assembly (GO:0035058)3.67342156
46female gamete generation (GO:0007292)3.63123187
47pyrimidine ribonucleoside biosynthetic process (GO:0046132)3.58201343
48otic vesicle formation (GO:0030916)3.57081638
49negative regulation of execution phase of apoptosis (GO:1900118)3.55539115
50positive regulation of gastrulation (GO:2000543)3.53477394
51deoxyribonucleoside diphosphate metabolic process (GO:0009186)3.52619558
52cell projection assembly (GO:0030031)3.51835552
53pyrimidine ribonucleotide biosynthetic process (GO:0009220)3.41640490
54central nervous system myelination (GO:0022010)3.36863808
55axon ensheathment in central nervous system (GO:0032291)3.36863808
56ADP metabolic process (GO:0046031)3.33752571
57brain morphogenesis (GO:0048854)3.32260561
58ribonucleoside triphosphate biosynthetic process (GO:0009201)3.28719567
59male meiosis I (GO:0007141)3.26450108
60neuron fate determination (GO:0048664)3.26272769
61determination of left/right symmetry (GO:0007368)3.24758358
62limb bud formation (GO:0060174)3.23719035
63inositol phosphate catabolic process (GO:0071545)3.23141718
64inositol phosphate dephosphorylation (GO:0046855)3.22170106
65phosphorylated carbohydrate dephosphorylation (GO:0046838)3.22170106
66regulation of microtubule-based movement (GO:0060632)3.21841565
67dopamine biosynthetic process (GO:0042416)3.18594614
68behavioral response to nicotine (GO:0035095)3.16279809
69centriole replication (GO:0007099)3.12412728
70glycerophospholipid catabolic process (GO:0046475)3.11931480
71nucleoside triphosphate biosynthetic process (GO:0009142)3.10332467
72regulation of steroid hormone secretion (GO:2000831)3.08563063
73determination of bilateral symmetry (GO:0009855)3.05813775
74sperm-egg recognition (GO:0035036)3.04332632
75regulation of calcium ion-dependent exocytosis (GO:0017158)3.02704569
76somite rostral/caudal axis specification (GO:0032525)3.02585694
77pyrimidine ribonucleotide metabolic process (GO:0009218)3.02261598
78synapsis (GO:0007129)3.01937153
79binding of sperm to zona pellucida (GO:0007339)3.01681671
80fusion of sperm to egg plasma membrane (GO:0007342)3.01477129
81sensory perception of smell (GO:0007608)3.00902544
82spermatid development (GO:0007286)3.00137680
83regulation of glucose import in response to insulin stimulus (GO:2001273)2.99566411
84single fertilization (GO:0007338)2.98490282
85specification of symmetry (GO:0009799)2.98384489
86magnesium ion transport (GO:0015693)2.98242139
87left/right pattern formation (GO:0060972)2.97225780
88gas transport (GO:0015669)2.97016493
89positive regulation of meiosis (GO:0045836)2.96930065
90nucleobase catabolic process (GO:0046113)2.96909968
91negative regulation of reproductive process (GO:2000242)2.93997429
92negative regulation of inclusion body assembly (GO:0090084)2.93828230
93multicellular organismal aging (GO:0010259)2.93017062
94reproduction (GO:0000003)2.92094302
95nitric oxide biosynthetic process (GO:0006809)2.88871390
96one-carbon compound transport (GO:0019755)2.88557795
97regulation of cell maturation (GO:1903429)2.88063858
98retinal rod cell development (GO:0046548)2.87706731
99mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.84588731
100spermatid nucleus differentiation (GO:0007289)2.84449646
101acrosome assembly (GO:0001675)2.83197657
102protein polyglutamylation (GO:0018095)2.82986807
103dendritic spine morphogenesis (GO:0060997)2.82416443
104positive regulation of meiotic cell cycle (GO:0051446)2.80380849
105gene silencing by RNA (GO:0031047)2.79615071
106phosphorelay signal transduction system (GO:0000160)2.75975838
107regulation of inclusion body assembly (GO:0090083)2.72514423
108fertilization (GO:0009566)2.72108952
109pyrimidine ribonucleoside metabolic process (GO:0046131)2.71991227
110pyrimidine nucleobase catabolic process (GO:0006208)2.71160182
111photoreceptor cell maintenance (GO:0045494)2.70307816
112microtubule severing (GO:0051013)2.69921053
113male meiosis (GO:0007140)2.69098988
114multicellular organism reproduction (GO:0032504)2.67942112
115ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.67331292
116smoothened signaling pathway (GO:0007224)2.66933738
117centriole assembly (GO:0098534)2.66522068
118neurotransmitter-gated ion channel clustering (GO:0072578)2.65839987
119purine ribonucleoside diphosphate metabolic process (GO:0009179)2.64717014
120purine nucleoside diphosphate metabolic process (GO:0009135)2.64717014
121pyrimidine nucleotide biosynthetic process (GO:0006221)2.63883698
122L-fucose catabolic process (GO:0042355)2.62654777
123fucose catabolic process (GO:0019317)2.62654777
124L-fucose metabolic process (GO:0042354)2.62654777
125pyrimidine-containing compound transmembrane transport (GO:0072531)2.62476923
126photoreceptor cell differentiation (GO:0046530)2.61401273
127eye photoreceptor cell differentiation (GO:0001754)2.61401273
128neuron cell-cell adhesion (GO:0007158)2.61038963
129mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.58896195
130cell wall macromolecule metabolic process (GO:0044036)2.58235253
131cell wall macromolecule catabolic process (GO:0016998)2.58235253
132keratinocyte development (GO:0003334)2.58083873
133cell-cell recognition (GO:0009988)2.57406972
134detection of calcium ion (GO:0005513)2.55971600
135polyol catabolic process (GO:0046174)2.55843070
136negative regulation of cAMP-mediated signaling (GO:0043951)2.55622171
137regulation of pigment cell differentiation (GO:0050932)2.54603413
138phospholipid dephosphorylation (GO:0046839)2.53890851
139gamma-aminobutyric acid transport (GO:0015812)2.51297358
140regulation of meiosis (GO:0040020)2.51096663
141calcium ion-dependent exocytosis (GO:0017156)2.49713157
142retina layer formation (GO:0010842)2.48490937
143base-excision repair, AP site formation (GO:0006285)2.47685678
144female mating behavior (GO:0060180)2.47244256
145regulation of macrophage chemotaxis (GO:0010758)2.47123380
146cerebral cortex neuron differentiation (GO:0021895)2.45952743
147aggressive behavior (GO:0002118)2.45873280
148regulation of mononuclear cell migration (GO:0071675)2.44113616
149ATP synthesis coupled proton transport (GO:0015986)2.42462231
150energy coupled proton transport, down electrochemical gradient (GO:0015985)2.42462231
151single strand break repair (GO:0000012)2.41724686
152synaptic vesicle maturation (GO:0016188)2.39886769
153establishment of melanosome localization (GO:0032401)2.39392881
154phosphatidylinositol dephosphorylation (GO:0046856)2.38530513
155negative regulation of transcription regulatory region DNA binding (GO:2000678)2.37845046
156meiosis I (GO:0007127)2.32859228
157positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.32847485
158positive regulation of mitotic sister chromatid separation (GO:1901970)2.32847485
159positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.32847485
160neurofilament cytoskeleton organization (GO:0060052)2.30740207
161neurotransmitter secretion (GO:0007269)2.30512452
162negative regulation of hormone biosynthetic process (GO:0032353)2.29357563
163cilium movement (GO:0003341)13.5121996
164axonemal dynein complex assembly (GO:0070286)12.6169984
165epithelial cilium movement (GO:0003351)10.9939918
166cilium or flagellum-dependent cell motility (GO:0001539)10.8408617
167axoneme assembly (GO:0035082)10.3610336
168epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)10.0310080

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse5.35727603
2EZH2_22144423_ChIP-Seq_EOC_Human4.38893492
3CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.11590657
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.90953844
5RBPJ_22232070_ChIP-Seq_NCS_Mouse2.64384350
6ZNF274_21170338_ChIP-Seq_K562_Hela2.57503534
7BMI1_23680149_ChIP-Seq_NPCS_Mouse2.24533822
8GBX2_23144817_ChIP-Seq_PC3_Human2.19750704
9GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.08571119
10TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.02897353
11CBX2_27304074_Chip-Seq_ESCs_Mouse2.02575606
12EZH2_27304074_Chip-Seq_ESCs_Mouse1.97672115
13RNF2_27304074_Chip-Seq_NSC_Mouse1.97244525
14CTBP2_25329375_ChIP-Seq_LNCAP_Human1.93804172
15SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.91853622
16JARID2_20064375_ChIP-Seq_MESCs_Mouse1.90392894
17BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.84544670
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.80871142
19EZH2_27294783_Chip-Seq_ESCs_Mouse1.79974778
20ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79841982
21EED_16625203_ChIP-ChIP_MESCs_Mouse1.79720949
22TAF15_26573619_Chip-Seq_HEK293_Human1.79525614
23SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77680115
24P300_19829295_ChIP-Seq_ESCs_Human1.77503959
25CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74686976
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.73877482
27JARID2_20075857_ChIP-Seq_MESCs_Mouse1.73727794
28SMAD4_21799915_ChIP-Seq_A2780_Human1.73087064
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.72645176
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.72066369
31SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.66094506
32REST_21632747_ChIP-Seq_MESCs_Mouse1.65939509
33SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.65252836
34ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.65005836
35ER_23166858_ChIP-Seq_MCF-7_Human1.64927696
36POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.64129415
37TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64129415
38SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.63155447
39IGF1R_20145208_ChIP-Seq_DFB_Human1.62118306
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.61377537
41GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.59422456
42AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.54240101
43AR_21572438_ChIP-Seq_LNCaP_Human1.53482607
44TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.53181040
45EZH2_18974828_ChIP-Seq_MESCs_Mouse1.49847594
46RNF2_18974828_ChIP-Seq_MESCs_Mouse1.49847594
47TCF4_23295773_ChIP-Seq_U87_Human1.49119739
48UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.48202918
49MTF2_20144788_ChIP-Seq_MESCs_Mouse1.48028500
50AR_25329375_ChIP-Seq_VCAP_Human1.47183718
51PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46981063
52CDX2_19796622_ChIP-Seq_MESCs_Mouse1.45329964
53EWS_26573619_Chip-Seq_HEK293_Human1.43625018
54CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.42815556
55SUZ12_27294783_Chip-Seq_NPCs_Mouse1.41608407
56TOP2B_26459242_ChIP-Seq_MCF-7_Human1.40341954
57GATA1_26923725_Chip-Seq_HPCs_Mouse1.39990661
58VDR_22108803_ChIP-Seq_LS180_Human1.39818804
59SALL1_21062744_ChIP-ChIP_HESCs_Human1.38967764
60EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.38417724
61TP53_22573176_ChIP-Seq_HFKS_Human1.38392448
62NANOG_18555785_Chip-Seq_ESCs_Mouse1.37841778
63PIAS1_25552417_ChIP-Seq_VCAP_Human1.37594497
64RNF2_27304074_Chip-Seq_ESCs_Mouse1.37592295
65FLI1_27457419_Chip-Seq_LIVER_Mouse1.37186027
66PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.36644795
67NR3C1_21868756_ChIP-Seq_MCF10A_Human1.36535741
68SMAD3_21741376_ChIP-Seq_EPCs_Human1.35848761
69RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.35383920
70DROSHA_22980978_ChIP-Seq_HELA_Human1.34736550
71SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33894162
72BCAT_22108803_ChIP-Seq_LS180_Human1.33312432
73PCGF2_27294783_Chip-Seq_ESCs_Mouse1.32482764
74TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.32386136
75EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.31931304
76SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.31375267
77PCGF2_27294783_Chip-Seq_NPCs_Mouse1.30931128
78OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26498152
79SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.25549779
80MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.22741243
81SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.22086534
82MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21115836
83P53_22387025_ChIP-Seq_ESCs_Mouse1.20644867
84STAT3_18555785_Chip-Seq_ESCs_Mouse1.20635258
85FUS_26573619_Chip-Seq_HEK293_Human1.19445263
86HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.19165243
87HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.17084186
88HTT_18923047_ChIP-ChIP_STHdh_Human1.16025563
89PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.16010086
90LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15937097
91CBP_20019798_ChIP-Seq_JUKART_Human1.15807494
92IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15807494
93SUZ12_18555785_Chip-Seq_ESCs_Mouse1.15585000
94E2F1_18555785_Chip-Seq_ESCs_Mouse1.15450719
95NFE2_27457419_Chip-Seq_LIVER_Mouse1.15240196
96PRDM14_20953172_ChIP-Seq_ESCs_Human1.14416694
97TAL1_26923725_Chip-Seq_HPCs_Mouse1.14276905
98EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.13734842
99TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.12138224
100CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11635576
101CMYC_18555785_Chip-Seq_ESCs_Mouse1.11581547
102P300_18555785_Chip-Seq_ESCs_Mouse1.11272181
103RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.11133162
104TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.10890990
105ZFX_18555785_Chip-Seq_ESCs_Mouse1.10887557
106HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.10521186
107EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10337872
108NCOR_22424771_ChIP-Seq_293T_Human1.10219341
109SOX2_18555785_Chip-Seq_ESCs_Mouse1.09887111
110NANOG_19829295_ChIP-Seq_ESCs_Human1.09348816
111SOX2_19829295_ChIP-Seq_ESCs_Human1.09348816
112FLI1_21867929_ChIP-Seq_TH2_Mouse1.08691905
113GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.08159128
114NR3C1_23031785_ChIP-Seq_PC12_Mouse1.07444440
115SOX2_21211035_ChIP-Seq_LN229_Gbm1.07309174
116EZH2_27294783_Chip-Seq_NPCs_Mouse1.07203691
117RING1B_27294783_Chip-Seq_ESCs_Mouse1.06606067
118REST_18959480_ChIP-ChIP_MESCs_Mouse1.06467777
119TCF4_22108803_ChIP-Seq_LS180_Human1.05724680
120STAT3_23295773_ChIP-Seq_U87_Human1.05467748
121CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.05116702
122SMAD4_21741376_ChIP-Seq_EPCs_Human1.04813206
123CRX_20693478_ChIP-Seq_RETINA_Mouse1.04429890
124RUNX2_22187159_ChIP-Seq_PCA_Human1.04299754
125TRIM28_21343339_ChIP-Seq_HEK293_Human1.03876916
126OCT4_18555785_Chip-Seq_ESCs_Mouse1.03128795
127IRF1_19129219_ChIP-ChIP_H3396_Human1.02539778
128TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00913179
129NOTCH1_21737748_ChIP-Seq_TLL_Human1.00415597
130KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99995746
131NANOG_20526341_ChIP-Seq_ESCs_Human0.98410218
132MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.98000961
133ETV2_25802403_ChIP-Seq_MESCs_Mouse0.94210890
134FOXA1_27270436_Chip-Seq_PROSTATE_Human0.94027214
135FOXA1_25329375_ChIP-Seq_VCAP_Human0.94027214
136FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93787157
137CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.93122484
138JUN_21703547_ChIP-Seq_K562_Human0.93018445
139FOXH1_21741376_ChIP-Seq_EPCs_Human0.92417648
140FOXA1_21572438_ChIP-Seq_LNCaP_Human0.89884810
141GATA3_21878914_ChIP-Seq_MCF-7_Human0.89278861

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color4.69084679
2MP0003718_maternal_effect4.43275174
3MP0008877_abnormal_DNA_methylation4.15424378
4MP0005410_abnormal_fertilization3.53536231
5MP0005646_abnormal_pituitary_gland3.42204890
6MP0002653_abnormal_ependyma_morphology3.15551767
7MP0001984_abnormal_olfaction3.15478329
8MP0005623_abnormal_meninges_morphology2.77642424
9MP0002102_abnormal_ear_morphology2.73011531
10MP0002638_abnormal_pupillary_reflex2.68355092
11MP0003787_abnormal_imprinting2.63151458
12MP0002132_abnormal_respiratory_system2.33008763
13MP0009046_muscle_twitch2.25464186
14MP0005645_abnormal_hypothalamus_physiol2.23956533
15MP0006292_abnormal_olfactory_placode2.23054301
16MP0003879_abnormal_hair_cell2.14057176
17MP0003880_abnormal_central_pattern2.10285160
18MP0002139_abnormal_hepatobiliary_system2.06143691
19MP0003122_maternal_imprinting2.05103095
20MP0003890_abnormal_embryonic-extraembry2.04304198
21MP0003121_genomic_imprinting1.99994286
22MP0006072_abnormal_retinal_apoptosis1.95527591
23MP0009780_abnormal_chondrocyte_physiolo1.94214834
24MP0006276_abnormal_autonomic_nervous1.86389761
25MP0001968_abnormal_touch/_nociception1.79089651
26MP0005395_other_phenotype1.77952275
27MP0002734_abnormal_mechanical_nocicepti1.71638594
28MP0001440_abnormal_grooming_behavior1.70466839
29MP0002572_abnormal_emotion/affect_behav1.69570960
30MP0002736_abnormal_nociception_after1.69319814
31MP0005379_endocrine/exocrine_gland_phen1.66075230
32MP0000631_abnormal_neuroendocrine_gland1.65466154
33MP0003698_abnormal_male_reproductive1.63995242
34MP0003690_abnormal_glial_cell1.62476531
35MP0010234_abnormal_vibrissa_follicle1.61211049
36MP0002557_abnormal_social/conspecific_i1.61165899
37MP0004133_heterotaxia1.57355234
38MP0000049_abnormal_middle_ear1.55983360
39MP0009745_abnormal_behavioral_response1.54488401
40MP0000778_abnormal_nervous_system1.53208555
41MP0001188_hyperpigmentation1.53039870
42MP0002064_seizures1.52717485
43MP0005551_abnormal_eye_electrophysiolog1.50087886
44MP0002277_abnormal_respiratory_mucosa1.49627119
45MP0004270_analgesia1.48560293
46MP0002272_abnormal_nervous_system1.48512057
47MP0004859_abnormal_synaptic_plasticity1.48233288
48MP0001486_abnormal_startle_reflex1.47606791
49MP0002876_abnormal_thyroid_physiology1.46299137
50MP0003635_abnormal_synaptic_transmissio1.44739165
51MP0002160_abnormal_reproductive_system1.44262990
52MP0002249_abnormal_larynx_morphology1.43952787
53MP0002210_abnormal_sex_determination1.39390349
54MP0002735_abnormal_chemical_nociception1.39105061
55MP0004142_abnormal_muscle_tone1.37704215
56MP0001502_abnormal_circadian_rhythm1.35918069
57MP0005253_abnormal_eye_physiology1.35635120
58MP0001529_abnormal_vocalization1.32814920
59MP0009250_abnormal_appendicular_skeleto1.31684569
60MP0001501_abnormal_sleep_pattern1.31538011
61MP0002063_abnormal_learning/memory/cond1.30096773
62MP0001485_abnormal_pinna_reflex1.26823936
63MP0003195_calcinosis1.23139084
64MP0001944_abnormal_pancreas_morphology1.22626670
65MP0002282_abnormal_trachea_morphology1.21087232
66MP0010386_abnormal_urinary_bladder1.19743830
67MP0001929_abnormal_gametogenesis1.19199030
68MP0004019_abnormal_vitamin_homeostasis1.17316884
69MP0000026_abnormal_inner_ear1.16831377
70MP0003938_abnormal_ear_development1.15537221
71MP0002184_abnormal_innervation1.15024613
72MP0002909_abnormal_adrenal_gland1.14787081
73MP0003634_abnormal_glial_cell1.14726344
74MP0000427_abnormal_hair_cycle1.14592658
75MP0000653_abnormal_sex_gland1.13917874
76MP0004858_abnormal_nervous_system1.13855928
77MP0001905_abnormal_dopamine_level1.13722337
78MP0005389_reproductive_system_phenotype1.11233137
79MP0001970_abnormal_pain_threshold1.10461470
80MP0004043_abnormal_pH_regulation1.09329216
81MP0004885_abnormal_endolymph1.09089248
82MP0005386_behavior/neurological_phenoty1.08851075
83MP0004924_abnormal_behavior1.08851075
84MP0005248_abnormal_Harderian_gland1.08614990
85MP0008004_abnormal_stomach_pH1.07886444
86MP0005423_abnormal_somatic_nervous1.07241181
87MP0002067_abnormal_sensory_capabilities1.06659739
88MP0004742_abnormal_vestibular_system1.05750642
89MP0004381_abnormal_hair_follicle1.04931790
90MP0003699_abnormal_female_reproductive1.04726711
91MP0004145_abnormal_muscle_electrophysio1.02325656
92MP0008875_abnormal_xenobiotic_pharmacok1.02086548
93MP0009384_cardiac_valve_regurgitation1.01861222
94MP0002733_abnormal_thermal_nociception1.00163969
95MP0002938_white_spotting0.99203597
96MP0005360_urolithiasis0.97980426
97MP0003011_delayed_dark_adaptation0.97687119
98MP0002229_neurodegeneration0.95661209
99MP0004811_abnormal_neuron_physiology0.95651304
100MP0000566_synostosis0.95335789
101MP0002882_abnormal_neuron_morphology0.94276051
102MP0001145_abnormal_male_reproductive0.94085981
103MP0002752_abnormal_somatic_nervous0.93978435
104MP0000013_abnormal_adipose_tissue0.93299421
105MP0002234_abnormal_pharynx_morphology0.90213393
106MP0002928_abnormal_bile_duct0.89675043
107MP0008789_abnormal_olfactory_epithelium0.88635885
108MP0001919_abnormal_reproductive_system0.88573360
109MP0002822_catalepsy0.87481977
110MP0001963_abnormal_hearing_physiology0.87066574
111MP0002138_abnormal_hepatobiliary_system0.85824293
112MP0001756_abnormal_urination0.85511665
113MP0005409_darkened_coat_color0.85195981
114MP0002152_abnormal_brain_morphology0.85097890
115MP0002177_abnormal_outer_ear0.85018204
116MP0000613_abnormal_salivary_gland0.84310956
117MP0001765_abnormal_ion_homeostasis0.84090608
118MP0004134_abnormal_chest_morphology0.83989477
119MP0005187_abnormal_penis_morphology0.83191272
120MP0002163_abnormal_gland_morphology0.82183511
121MP0002233_abnormal_nose_morphology0.81923526
122MP0002295_abnormal_pulmonary_circulatio0.80592675
123MP0009379_abnormal_foot_pigmentation0.79574399
124MP0003937_abnormal_limbs/digits/tail_de0.78917299
125MP0005394_taste/olfaction_phenotype0.78079773
126MP0005499_abnormal_olfactory_system0.78079773
127MP0001270_distended_abdomen0.77601145
128MP0001986_abnormal_taste_sensitivity0.76132202
129MP0002837_dystrophic_cardiac_calcinosis0.74794954
130MP0002069_abnormal_eating/drinking_beha0.74402259
131MP0000955_abnormal_spinal_cord0.74122267
132MP0002161_abnormal_fertility/fecundity0.73531343
133MP0001664_abnormal_digestion0.73455590
134MP0005195_abnormal_posterior_eye0.72232560
135MP0008872_abnormal_physiological_respon0.72132200
136MP0002116_abnormal_craniofacial_bone0.70582801

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium morphology (HP:0005938)9.85870509
2Abnormal respiratory epithelium morphology (HP:0012253)9.85870509
3Rhinitis (HP:0012384)9.70192738
4Dynein arm defect of respiratory motile cilia (HP:0012255)8.06096794
5Absent/shortened dynein arms (HP:0200106)8.06096794
6Bronchiectasis (HP:0002110)5.48082354
7Chronic bronchitis (HP:0004469)4.99791375
8Chronic sinusitis (HP:0011109)4.41475850
9Pancreatic fibrosis (HP:0100732)3.80903413
10Nephronophthisis (HP:0000090)3.72770346
11True hermaphroditism (HP:0010459)3.61984143
12Medial flaring of the eyebrow (HP:0010747)3.50970655
13Recurrent sinusitis (HP:0011108)3.49042240
14Nasal polyposis (HP:0100582)3.43831983
15Gait imbalance (HP:0002141)3.20466800
16Molar tooth sign on MRI (HP:0002419)3.18793144
17Abnormality of midbrain morphology (HP:0002418)3.18793144
18Congenital primary aphakia (HP:0007707)3.17668433
19Median cleft lip (HP:0000161)3.01766701
20Male infertility (HP:0003251)3.00209114
21Infertility (HP:0000789)2.94101478
22Abnormality of the renal medulla (HP:0100957)2.89060629
23Osteomalacia (HP:0002749)2.88622067
24Aplasia/Hypoplasia of the fovea (HP:0008060)2.81706373
25Hypoplasia of the fovea (HP:0007750)2.81706373
26Nephrogenic diabetes insipidus (HP:0009806)2.80832713
27Bronchitis (HP:0012387)2.73157115
28Abnormality of the nasal mucosa (HP:0000433)2.72197544
29Taurodontia (HP:0000679)2.70720370
30Abnormality of permanent molar morphology (HP:0011071)2.70720370
31Abnormality of the dental root (HP:0006486)2.70720370
32Abnormality of dentin (HP:0010299)2.70080768
33Pancreatic cysts (HP:0001737)2.64701314
34Abnormality of aromatic amino acid family metabolism (HP:0004338)2.61936944
35Abnormality of the labia minora (HP:0012880)2.58271621
36Abnormality of the dental pulp (HP:0006479)2.58122531
37Occipital encephalocele (HP:0002085)2.58016550
38Abnormality of molar (HP:0011077)2.55908951
39Abnormality of molar morphology (HP:0011070)2.55908951
40Congenital hepatic fibrosis (HP:0002612)2.54894731
41Esophageal neoplasm (HP:0100751)2.54605910
42Neoplasm of head and neck (HP:0012288)2.54605910
43Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.52756637
44Anterior segment dysgenesis (HP:0007700)2.52104780
45Myokymia (HP:0002411)2.50758967
46Abnormality of the fovea (HP:0000493)2.41385197
47Tubulointerstitial nephritis (HP:0001970)2.41168403
48Genital tract atresia (HP:0001827)2.40900650
49Short tibia (HP:0005736)2.39584564
50Hypophosphatemic rickets (HP:0004912)2.32278250
51Vaginal atresia (HP:0000148)2.29024424
52Aplasia/Hypoplasia of the tibia (HP:0005772)2.27190498
53Cystic liver disease (HP:0006706)2.27154282
54Progressive cerebellar ataxia (HP:0002073)2.27038538
55Oligodactyly (hands) (HP:0001180)2.24811849
56Enlarged penis (HP:0000040)2.24494597
57Gaze-evoked nystagmus (HP:0000640)2.24412115
58Poor coordination (HP:0002370)2.23554961
59Stage 5 chronic kidney disease (HP:0003774)2.22225500
60Postaxial foot polydactyly (HP:0001830)2.21666052
61Aplasia/Hypoplasia of the lens (HP:0008063)2.18270419
62Atelectasis (HP:0100750)2.17939449
63Recurrent otitis media (HP:0000403)2.17651078
64Type II lissencephaly (HP:0007260)2.13382067
65Double outlet right ventricle (HP:0001719)2.11270725
66Congenital malformation of the right heart (HP:0011723)2.11270725
67Polyphagia (HP:0002591)2.06825556
68Hypokinesia (HP:0002375)2.06724085
69Proximal tubulopathy (HP:0000114)2.06608678
70Limb dystonia (HP:0002451)2.05822507
71Intestinal atresia (HP:0011100)2.05407387
72Congenital sensorineural hearing impairment (HP:0008527)2.03730555
73Aplasia/Hypoplasia of the tongue (HP:0010295)2.03638446
74Abnormality of calcium-phosphate metabolism (HP:0100530)2.01664468
75Abnormal ciliary motility (HP:0012262)12.2492860
76Abnormal respiratory motile cilium physiology (HP:0012261)11.6399104
77Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.5551606
78Preaxial hand polydactyly (HP:0001177)1.99314028
79Postaxial hand polydactyly (HP:0001162)1.98813511
80Methylmalonic acidemia (HP:0002912)1.97676729
81Azoospermia (HP:0000027)1.96493598
82EEG with generalized epileptiform discharges (HP:0011198)1.88774685
83Fetal akinesia sequence (HP:0001989)1.88658935
84Hypothermia (HP:0002045)1.87077795
85Short nail (HP:0001799)1.86460304
86Epileptiform EEG discharges (HP:0011182)1.85856498
87Hypsarrhythmia (HP:0002521)1.84705207
88Pachygyria (HP:0001302)1.83985502
89Abnormal rod and cone electroretinograms (HP:0008323)1.83745025
90Tubulointerstitial abnormality (HP:0001969)1.83656397
91Poor suck (HP:0002033)1.83308574
92Concave nail (HP:0001598)1.81474948
93Renal cortical cysts (HP:0000803)1.80843375
94Facial cleft (HP:0002006)1.80758471
95Papillary thyroid carcinoma (HP:0002895)1.80702241
96Malnutrition (HP:0004395)1.79135510
97Lissencephaly (HP:0001339)1.78704036
98Male pseudohermaphroditism (HP:0000037)1.76158943
99Decreased circulating renin level (HP:0003351)1.75377265
100Abnormal sex determination (HP:0012244)1.75321544
101Sex reversal (HP:0012245)1.75321544
102Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.74610493
103Limb hypertonia (HP:0002509)1.73759305
104Septo-optic dysplasia (HP:0100842)1.72591790
105Sclerocornea (HP:0000647)1.72083921
106Agitation (HP:0000713)1.70416939
107Abnormality of urine glucose concentration (HP:0011016)1.70074868
108Glycosuria (HP:0003076)1.70074868
109Supernumerary spleens (HP:0009799)1.69037730
110Retinal dysplasia (HP:0007973)1.68946096
111Optic nerve hypoplasia (HP:0000609)1.68818555
112Epileptic encephalopathy (HP:0200134)1.68498124
113Tubular atrophy (HP:0000092)1.67631301
114Oculomotor apraxia (HP:0000657)1.64442224
115Anencephaly (HP:0002323)1.62479956
116Ectopic anus (HP:0004397)1.61533675
117Bifid tongue (HP:0010297)1.58320685
118Specific learning disability (HP:0001328)1.58147958
119Aplasia involving bones of the upper limbs (HP:0009823)1.55916001
120Aplasia of the phalanges of the hand (HP:0009802)1.55916001
121Aplasia involving bones of the extremities (HP:0009825)1.55916001
122Fibular hypoplasia (HP:0003038)1.55549117
123Abnormal biliary tract physiology (HP:0012439)1.51883815
124Bile duct proliferation (HP:0001408)1.51883815
125Hyperventilation (HP:0002883)1.51383370
126Retinitis pigmentosa (HP:0000510)1.46774879
127Decreased central vision (HP:0007663)1.45917342
128Abnormality of renal resorption (HP:0011038)1.43963745
129Increased hepatocellular lipid droplets (HP:0006565)1.43243642
130Abnormality of abdominal situs (HP:0011620)1.41797818
131Abdominal situs inversus (HP:0003363)1.41797818
132Nephropathy (HP:0000112)1.41756187
133Aganglionic megacolon (HP:0002251)1.38008004
134Chronic hepatic failure (HP:0100626)1.37657452
135Tubulointerstitial fibrosis (HP:0005576)1.36122945
136Hypodontia (HP:0000668)1.35836030
137Broad foot (HP:0001769)1.34735048
138Abnormality of macular pigmentation (HP:0008002)1.34581497
139Bony spicule pigmentary retinopathy (HP:0007737)1.33589385
140Hypotelorism (HP:0000601)1.33438681
141Renal Fanconi syndrome (HP:0001994)1.32561523
142Optic disc pallor (HP:0000543)1.30186984
143Acute necrotizing encephalopathy (HP:0006965)1.30014083
144Polydipsia (HP:0001959)1.29112657
145Abnormal drinking behavior (HP:0030082)1.29112657
146Abnormality of the renal cortex (HP:0011035)1.28530453
147Bell-shaped thorax (HP:0001591)1.26127133
148Mitochondrial inheritance (HP:0001427)1.25964334
149Narrow forehead (HP:0000341)1.23940001
150Recurrent bronchitis (HP:0002837)1.22067609

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK158.27049785
2PNCK4.25031130
3MAP3K94.06742216
4CASK3.77682794
5FRK3.08935797
6NTRK22.99958042
7TRIM282.96754619
8MAP3K132.36724435
9STK242.24188643
10MAP2K71.95239711
11MAP4K21.88809979
12MARK11.76971878
13GRK11.73339375
14NTRK31.72036536
15IRAK11.66924696
16CDK31.64477967
17PIK3CG1.61499238
18LMTK21.50656903
19MST41.43390493
20PDK31.43275681
21PDK41.43275681
22PHKG21.43272404
23PHKG11.43272404
24CSNK1G21.40314934
25TNIK1.37403233
26WNK31.36338979
27TAOK31.35823765
28CSNK1G31.33871805
29PRKCI1.32653998
30MKNK21.30775622
31GRK71.30488512
32CSNK1G11.28807175
33MAPK131.27924068
34ADRBK21.24090508
35CDK91.23594870
36WNK41.22636997
37PRKD31.22044418
38DAPK21.21121723
39BCR1.19489450
40PDK21.10040995
41STK38L1.09996790
42MAP3K41.09661268
43STK161.08422662
44PRKCG1.08335327
45SIK11.07852025
46KSR11.07254588
47ERBB31.04243009
48EPHA41.00268927
49FGFR20.97825515
50CSNK1A1L0.96473070
51VRK10.95045071
52CAMK2B0.93668269
53INSRR0.93087176
54ZAK0.92822269
55MUSK0.92797052
56PAK30.89503248
57PTK2B0.88941164
58RAF10.85442048
59ARAF0.85151268
60PRKCE0.85110036
61MET0.83345240
62CAMK2A0.82831425
63STK390.79892565
64MAPKAPK50.79040434
65CAMKK20.78431989
66MAP2K40.77427876
67DYRK30.76394005
68IRAK20.76194673
69MOS0.75534489
70DYRK1A0.74688132
71BMPR20.74382816
72DYRK20.74141671
73SIK30.73047347
74TAOK10.72351761
75KSR20.70900179
76MINK10.70437514
77ADRBK10.70178722
78NEK60.69194263
79PLK10.68039574
80CAMK2D0.67179806
81PAK20.67168573
82AKT30.66962830
83AURKA0.65105451
84TIE10.65037450
85PRKCZ0.64921994
86ACVR1B0.64791106
87UHMK10.64513457
88BMPR1B0.63698503
89ROCK20.63602368
90CDK190.63132968
91PKN10.62858170
92OXSR10.62703585
93PRPF4B0.62418409
94RPS6KA20.60592548
95PRKACA0.60071350
96TTK0.59777292
97MAP2K20.58370695
98NUAK10.57499397
99EPHA30.57383211
100STK30.57325011
101PINK10.54736861
102BLK0.54645533
103PRKG10.53477185
104MAPK120.52560668
105CSNK1D0.52518390
106YES10.51951947
107SGK2230.51949060
108SGK4940.51949060
109TRPM70.51923841
110CDK50.51649951
111TESK10.51208943
112STK380.50738187
113EIF2AK30.50493566
114CDC42BPA0.50111161
115OBSCN0.49964962
116GSK3A0.48793764
117CSNK1E0.48242973
118BRAF0.47352068
119CAMK2G0.46255713
120FGR0.45357233
121SGK20.45267461
122HIPK20.44914623
123PRKAA10.44818089
124PRKACB0.41155840
125MKNK10.40561410
126WNK10.39819183
127MAPK70.39625159
128SRPK10.39338638
129MAPKAPK30.39257223
130CAMK10.39075658
131SIK20.38677863
132FES0.38117883
133PRKACG0.36269116
134GRK50.35878309
135TNK20.35648229
136NME10.35484631
137MAP2K60.35158288
138RPS6KA50.34830852
139CSNK1A10.34552030
140STK110.34137968
141PIM20.33543578
142MAPK40.33479974
143PRKCA0.33221760
144BRSK20.32860386
145SGK10.32486846
146PLK20.32166401
147PRKAA20.31923062
148CAMK40.30729410

Predicted pathways (KEGG)

RankGene SetZ-score
1Oxidative phosphorylation_Homo sapiens_hsa001903.43696199
2Huntingtons disease_Homo sapiens_hsa050163.23335157
3Basal transcription factors_Homo sapiens_hsa030223.05376075
4Olfactory transduction_Homo sapiens_hsa047402.82145293
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.76887908
6Parkinsons disease_Homo sapiens_hsa050122.70772240
7Nicotine addiction_Homo sapiens_hsa050332.45942016
8Alzheimers disease_Homo sapiens_hsa050102.41651813
9Protein export_Homo sapiens_hsa030602.32809656
10Phototransduction_Homo sapiens_hsa047442.12223296
11Folate biosynthesis_Homo sapiens_hsa007902.04033758
12Insulin secretion_Homo sapiens_hsa049111.99727158
13Cardiac muscle contraction_Homo sapiens_hsa042601.95256403
14GABAergic synapse_Homo sapiens_hsa047271.90231750
15Amphetamine addiction_Homo sapiens_hsa050311.81012493
16Vitamin B6 metabolism_Homo sapiens_hsa007501.79750211
17Circadian entrainment_Homo sapiens_hsa047131.79490690
18Taste transduction_Homo sapiens_hsa047421.78529077
19Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.72296026
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.68929189
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.65986567
22Maturity onset diabetes of the young_Homo sapiens_hsa049501.65896913
23Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.65740557
24Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.63850944
25Ether lipid metabolism_Homo sapiens_hsa005651.62025037
26Oocyte meiosis_Homo sapiens_hsa041141.61407599
27Glutamatergic synapse_Homo sapiens_hsa047241.60117462
28Cocaine addiction_Homo sapiens_hsa050301.57364162
29Morphine addiction_Homo sapiens_hsa050321.54890641
30Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.51985741
31Circadian rhythm_Homo sapiens_hsa047101.50587098
32Calcium signaling pathway_Homo sapiens_hsa040201.50278113
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.39827707
34Serotonergic synapse_Homo sapiens_hsa047261.38642566
35Renin secretion_Homo sapiens_hsa049241.35881283
36Salivary secretion_Homo sapiens_hsa049701.35071868
37Collecting duct acid secretion_Homo sapiens_hsa049661.30250522
38Gastric acid secretion_Homo sapiens_hsa049711.25257789
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.15638408
40Fatty acid elongation_Homo sapiens_hsa000621.14751413
41Dopaminergic synapse_Homo sapiens_hsa047281.10639327
42ABC transporters_Homo sapiens_hsa020101.06565605
43Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.05903583
44Linoleic acid metabolism_Homo sapiens_hsa005911.05254176
45Purine metabolism_Homo sapiens_hsa002301.05233111
46Synaptic vesicle cycle_Homo sapiens_hsa047211.05047148
47Arachidonic acid metabolism_Homo sapiens_hsa005901.04300003
48SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03730373
49RNA degradation_Homo sapiens_hsa030181.03467532
50Sulfur metabolism_Homo sapiens_hsa009201.03423691
51Butanoate metabolism_Homo sapiens_hsa006501.02214516
52Aldosterone synthesis and secretion_Homo sapiens_hsa049251.00477506
53Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.00251148
54Vibrio cholerae infection_Homo sapiens_hsa051100.99407665
55Regulation of autophagy_Homo sapiens_hsa041400.96048087
56Vascular smooth muscle contraction_Homo sapiens_hsa042700.93263080
57Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91709557
58Long-term depression_Homo sapiens_hsa047300.91664062
59Peroxisome_Homo sapiens_hsa041460.90187725
60Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.89188489
61Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88794090
62alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.87122795
63cAMP signaling pathway_Homo sapiens_hsa040240.85555087
64Cholinergic synapse_Homo sapiens_hsa047250.84537268
65Glucagon signaling pathway_Homo sapiens_hsa049220.83833540
66Melanogenesis_Homo sapiens_hsa049160.83053336
67Thyroid hormone synthesis_Homo sapiens_hsa049180.82267234
68Fanconi anemia pathway_Homo sapiens_hsa034600.81097337
69RNA polymerase_Homo sapiens_hsa030200.80119249
70Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79655603
71Ovarian steroidogenesis_Homo sapiens_hsa049130.76386419
72Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.75778059
73cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75726436
74Inositol phosphate metabolism_Homo sapiens_hsa005620.75487402
75beta-Alanine metabolism_Homo sapiens_hsa004100.74959181
76Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74786623
77Dorso-ventral axis formation_Homo sapiens_hsa043200.74482896
78Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74254264
79Mineral absorption_Homo sapiens_hsa049780.74169209
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74083125
81Steroid biosynthesis_Homo sapiens_hsa001000.73718348
82Estrogen signaling pathway_Homo sapiens_hsa049150.73358955
83Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.72687000
84Sphingolipid metabolism_Homo sapiens_hsa006000.71543186
85Retinol metabolism_Homo sapiens_hsa008300.70996641
86Long-term potentiation_Homo sapiens_hsa047200.70733441
87Oxytocin signaling pathway_Homo sapiens_hsa049210.69819655
88Wnt signaling pathway_Homo sapiens_hsa043100.68941004
89Pancreatic secretion_Homo sapiens_hsa049720.66085219
90Glycosaminoglycan degradation_Homo sapiens_hsa005310.65067895
91Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63991344
92Selenocompound metabolism_Homo sapiens_hsa004500.63507973
93Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.62776300
94Cell cycle_Homo sapiens_hsa041100.62541149
95Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.62534572
96Pyruvate metabolism_Homo sapiens_hsa006200.62222254
97Axon guidance_Homo sapiens_hsa043600.62128783
98Primary bile acid biosynthesis_Homo sapiens_hsa001200.61256241
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60601968
100Basal cell carcinoma_Homo sapiens_hsa052170.59138985
101Hedgehog signaling pathway_Homo sapiens_hsa043400.57918063
102Gap junction_Homo sapiens_hsa045400.57523409
103Rheumatoid arthritis_Homo sapiens_hsa053230.57395964
104Alcoholism_Homo sapiens_hsa050340.56737958
105Metabolic pathways_Homo sapiens_hsa011000.56632682
106Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.55627803
107Histidine metabolism_Homo sapiens_hsa003400.54650699
108Fatty acid biosynthesis_Homo sapiens_hsa000610.54630475
109Cysteine and methionine metabolism_Homo sapiens_hsa002700.54600196
110GnRH signaling pathway_Homo sapiens_hsa049120.54258160
111Pyrimidine metabolism_Homo sapiens_hsa002400.52488614
112Caffeine metabolism_Homo sapiens_hsa002320.52254459
113Glycerophospholipid metabolism_Homo sapiens_hsa005640.51181967
114Prion diseases_Homo sapiens_hsa050200.50196271
115Type I diabetes mellitus_Homo sapiens_hsa049400.49793978
116Arginine biosynthesis_Homo sapiens_hsa002200.48952737
117Propanoate metabolism_Homo sapiens_hsa006400.48906082
118Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48773718
119Tryptophan metabolism_Homo sapiens_hsa003800.47192446
120Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.46333522
121Arginine and proline metabolism_Homo sapiens_hsa003300.46058318
122Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.42203424
123Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42088712
124Chemical carcinogenesis_Homo sapiens_hsa052040.40061020
125Dilated cardiomyopathy_Homo sapiens_hsa054140.36479771
126Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.36119717
127PPAR signaling pathway_Homo sapiens_hsa033200.35575346
128Phagosome_Homo sapiens_hsa041450.33171073
129Autoimmune thyroid disease_Homo sapiens_hsa053200.32240048
130Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.31372221
131Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30605008
132Bile secretion_Homo sapiens_hsa049760.29209681

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »