RILPL2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that contains a rab-interacting lysosomal protein-like domain. This protein may be involved in regulating lysosome morphology. This protein may also be a target for the Hepatitis C virus and assist in viral replication. Alternate splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neutrophil activation involved in immune response (GO:0002283)4.92310645
2polyketide metabolic process (GO:0030638)4.49031043
3doxorubicin metabolic process (GO:0044598)4.49031043
4daunorubicin metabolic process (GO:0044597)4.49031043
5antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.41975714
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.28689930
7positive regulation by organism of defense response of other organism involved in symbiotic interact4.28689930
8modulation by symbiont of host immune response (GO:0052553)4.28689930
9positive regulation by symbiont of host defense response (GO:0052509)4.28689930
10modulation by symbiont of host defense response (GO:0052031)4.28689930
11modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.28689930
12superoxide anion generation (GO:0042554)4.23180605
13negative regulation of cell killing (GO:0031342)4.12106392
14negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.12106392
15positive regulation of gamma-delta T cell activation (GO:0046645)4.06236009
16response to peptidoglycan (GO:0032494)4.04499047
17respiratory burst (GO:0045730)4.01336585
18positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.98559183
19regulation of gamma-delta T cell activation (GO:0046643)3.97767700
20neutrophil activation (GO:0042119)3.85811776
21granulocyte activation (GO:0036230)3.82188646
22leukocyte aggregation (GO:0070486)3.80065910
23regulation of B cell receptor signaling pathway (GO:0050855)3.72439333
24detection of molecule of bacterial origin (GO:0032490)3.71576093
25defense response to protozoan (GO:0042832)3.57989122
26positive regulation of antigen processing and presentation (GO:0002579)3.47193118
27regulation of gamma-delta T cell differentiation (GO:0045586)3.42149712
28tolerance induction (GO:0002507)3.41174725
29positive regulation of interleukin-1 beta secretion (GO:0050718)3.39463046
30response to muramyl dipeptide (GO:0032495)3.37710675
31positive regulation of B cell differentiation (GO:0045579)3.36510664
32B cell receptor signaling pathway (GO:0050853)3.32311420
33positive regulation of heat generation (GO:0031652)3.30327561
34germinal center formation (GO:0002467)3.29756057
35interferon-gamma-mediated signaling pathway (GO:0060333)3.29442383
36regulation of fever generation (GO:0031620)3.29158701
37macrophage activation involved in immune response (GO:0002281)3.26615075
38detection of bacterium (GO:0016045)3.25268749
39negative regulation of T cell mediated immunity (GO:0002710)3.23590619
40response to protozoan (GO:0001562)3.20986690
41positive regulation of chemokine biosynthetic process (GO:0045080)3.20496794
42B cell mediated immunity (GO:0019724)3.18290700
43negative regulation of interleukin-12 production (GO:0032695)3.17016833
44regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.16166641
45regulation of interleukin-12 biosynthetic process (GO:0045075)3.16072605
46lipopolysaccharide-mediated signaling pathway (GO:0031663)3.15666564
47negative regulation of lymphocyte mediated immunity (GO:0002707)3.14565436
48positive regulation of mast cell activation (GO:0033005)3.14175844
49positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.13773892
50T cell migration (GO:0072678)3.13322906
51monocyte chemotaxis (GO:0002548)3.13296713
52immunoglobulin mediated immune response (GO:0016064)3.13040664
53positive regulation of cellular amide metabolic process (GO:0034250)3.11847035
54regulation of dendritic cell antigen processing and presentation (GO:0002604)3.11776972
55myeloid dendritic cell activation (GO:0001773)3.11687116
56NIK/NF-kappaB signaling (GO:0038061)3.11363893
57myeloid cell activation involved in immune response (GO:0002275)3.10952141
58regulation of antigen processing and presentation (GO:0002577)3.10885142
59positive regulation of interleukin-1 secretion (GO:0050716)3.10622469
60regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.09636580
61response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.07968053
62response to host immune response (GO:0052572)3.07968053
63positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.07785914
64regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.06657332
65positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.06196082
66eosinophil chemotaxis (GO:0048245)3.04957005
67cellular response to interferon-beta (GO:0035458)3.03958511
68positive regulation of defense response to virus by host (GO:0002230)3.03827665
69macrophage activation (GO:0042116)3.03638407
70positive regulation of interleukin-10 production (GO:0032733)3.02530003
71detection of external biotic stimulus (GO:0098581)3.02129756
72myeloid dendritic cell differentiation (GO:0043011)3.02104799
73interferon-gamma production (GO:0032609)3.01433867
74cellular response to exogenous dsRNA (GO:0071360)3.01043310
75regulation of interleukin-1 beta secretion (GO:0050706)2.99776096
76regulation of chemokine biosynthetic process (GO:0045073)2.99329735
77neutrophil mediated immunity (GO:0002446)2.98771029
78regulation of activation of Janus kinase activity (GO:0010533)2.97699807
79regulation of mast cell degranulation (GO:0043304)2.96809811
80mature B cell differentiation (GO:0002335)2.96728539
81negative regulation of interleukin-6 production (GO:0032715)2.96677980
82microglial cell activation (GO:0001774)2.94777143
83negative regulation of mast cell activation (GO:0033004)2.92429492
84antigen processing and presentation of endogenous antigen (GO:0019883)2.91603036
85positive regulation of interferon-alpha production (GO:0032727)2.90810205
86T-helper 1 type immune response (GO:0042088)2.90798779
87response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.89705100
88response to host (GO:0075136)2.89705100
89response to host defenses (GO:0052200)2.89705100
90positive regulation of interleukin-17 production (GO:0032740)2.89563101
91regulation of interleukin-17 production (GO:0032660)2.88531821
92mast cell activation (GO:0045576)2.87738969
93cellular extravasation (GO:0045123)2.87387558
94leukocyte degranulation (GO:0043299)2.87313752
95detection of other organism (GO:0098543)2.86826482
96negative regulation of leukocyte mediated immunity (GO:0002704)2.86336921
97cellular response to type I interferon (GO:0071357)2.85852022
98type I interferon signaling pathway (GO:0060337)2.85852022
99mature B cell differentiation involved in immune response (GO:0002313)2.85290983
100positive thymic T cell selection (GO:0045059)2.84784705
101response to type I interferon (GO:0034340)2.84636665
102negative regulation of interleukin-17 production (GO:0032700)2.84632858
103negative regulation of cytokine production involved in immune response (GO:0002719)2.84555018
104regulation of interferon-alpha production (GO:0032647)2.83883439
105regulation of mast cell activation (GO:0033003)2.83569884
106regulation of interferon-beta biosynthetic process (GO:0045357)2.82741990
107myeloid leukocyte activation (GO:0002274)2.82654676
108negative thymic T cell selection (GO:0045060)2.82371116
109antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.81843497
110antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.81843497
111regulation of interleukin-12 production (GO:0032655)2.81216002
112aminoglycoside antibiotic metabolic process (GO:0030647)2.79978250
113positive regulation of interferon-gamma production (GO:0032729)2.78000610
114negative regulation of innate immune response (GO:0045824)2.77938642
115regulation of T-helper 1 cell differentiation (GO:0045625)2.77797922
116eosinophil migration (GO:0072677)2.77135145
117positive regulation of interleukin-12 production (GO:0032735)2.76640516
118regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.76300431
119positive regulation of isotype switching (GO:0045830)2.75232449
120positive regulation of cytokine biosynthetic process (GO:0042108)2.74850564
121detection of biotic stimulus (GO:0009595)2.74829836
122positive regulation of immunoglobulin mediated immune response (GO:0002891)2.74763569
123positive regulation of B cell mediated immunity (GO:0002714)2.74763569
124regulation of T cell mediated cytotoxicity (GO:0001914)2.74439635
125positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.73808096
126positive regulation of alpha-beta T cell proliferation (GO:0046641)2.73552071
127regulation of alpha-beta T cell proliferation (GO:0046640)2.73210631
128regulation of mast cell activation involved in immune response (GO:0033006)2.73189910
129regulation of B cell differentiation (GO:0045577)2.72914189
130negative regulation of growth of symbiont in host (GO:0044130)2.72791302
131negative regulation of growth of symbiont involved in interaction with host (GO:0044146)2.72791302
132regulation of growth of symbiont in host (GO:0044126)2.72791302
133negative T cell selection (GO:0043383)2.68090314
134positive regulation of interferon-beta production (GO:0032728)2.68005645
135regulation of germinal center formation (GO:0002634)2.67904323
136positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.67080851
137positive regulation of T cell mediated cytotoxicity (GO:0001916)2.66222359
138negative regulation of interleukin-1 beta production (GO:0032691)2.65989351

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.44608657
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.36550938
3IRF8_22096565_ChIP-ChIP_GC-B_Human5.20083767
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.30168466
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.93876498
6STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.47274110
7IRF8_27001747_Chip-Seq_BMDM_Mouse3.44000629
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.38953974
9* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.31180134
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.00027667
11STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.81599842
12STAT4_19710469_ChIP-ChIP_TH1__Mouse2.63112244
13* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.61459001
14SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.57834341
15* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.57671130
16SCL_19346495_ChIP-Seq_HPC-7_Human2.32149813
17* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.30977955
18GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.07771602
19RUNX_20019798_ChIP-Seq_JUKART_Human2.03847193
20NOTCH1_21737748_ChIP-Seq_TLL_Human1.99899517
21* MYB_21317192_ChIP-Seq_ERMYB_Mouse1.99204014
22* RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.96251857
23VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.94394388
24* SPI1_23547873_ChIP-Seq_NB4_Human1.91368519
25LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.90949890
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.89405168
27UTX_26944678_Chip-Seq_JUKART_Human1.88511491
28* MYC_22102868_ChIP-Seq_BL_Human1.86639304
29FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.81610845
30PCGF2_27294783_Chip-Seq_ESCs_Mouse1.80939134
31CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.75806779
32GATA3_27048872_Chip-Seq_THYMUS_Human1.74845130
33RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.71138840
34SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.69119945
35GATA1_22025678_ChIP-Seq_K562_Human1.69101974
36MAF_26560356_Chip-Seq_TH2_Human1.65380450
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.64882763
38PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.64263261
39* MYB_26560356_Chip-Seq_TH2_Human1.62653474
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57223465
41MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.55966454
42VDR_24787735_ChIP-Seq_THP-1_Human1.55440334
43VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.53709897
44SUZ12_27294783_Chip-Seq_NPCs_Mouse1.52942424
45GATA1_19941827_ChIP-Seq_MEL_Mouse1.52027955
46NFE2_27457419_Chip-Seq_LIVER_Mouse1.49269845
47PCGF2_27294783_Chip-Seq_NPCs_Mouse1.48773692
48SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.45593090
49FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43106527
50PU_27001747_Chip-Seq_BMDM_Mouse1.42179464
51LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.42174356
52ZFP57_27257070_Chip-Seq_ESCs_Mouse1.40265149
53GBX2_23144817_ChIP-Seq_PC3_Human1.40256978
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.40206251
55BCL6_27268052_Chip-Seq_Bcells_Human1.40105723
56IGF1R_20145208_ChIP-Seq_DFB_Human1.38241608
57EZH2_27294783_Chip-Seq_NPCs_Mouse1.36445964
58GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.32186367
59VDR_24763502_ChIP-Seq_THP-1_Human1.30733878
60GATA1_19941826_ChIP-Seq_K562_Human1.29918970
61BRD4_27068464_Chip-Seq_AML-cells_Mouse1.27492408
62PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.27302804
63IKZF1_21737484_ChIP-ChIP_HCT116_Human1.27231404
64KDM2B_26808549_Chip-Seq_SUP-B15_Human1.25951194
65MYB_26560356_Chip-Seq_TH1_Human1.25866118
66BCOR_27268052_Chip-Seq_Bcells_Human1.25261229
67CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.24463470
68TP63_19390658_ChIP-ChIP_HaCaT_Human1.22493954
69GATA2_22383799_ChIP-Seq_G1ME_Mouse1.21214771
70SUZ12_18555785_Chip-Seq_ESCs_Mouse1.20442280
71STAT3_18555785_Chip-Seq_ESCs_Mouse1.19322036
72* RUNX1_22412390_ChIP-Seq_EML_Mouse1.18516669
73ELF1_17652178_ChIP-ChIP_JURKAT_Human1.17050727
74GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16747712
75EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.16492768
76P53_22387025_ChIP-Seq_ESCs_Mouse1.15254627
77* TCF7_22412390_ChIP-Seq_EML_Mouse1.15150028
78GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.14801166
79NMYC_18555785_Chip-Seq_ESCs_Mouse1.13246721
80STAT1_20625510_ChIP-Seq_HELA_Human1.12378923
81POU3F2_20337985_ChIP-ChIP_501MEL_Human1.11906486
82TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.10314388
83RUNX1_27457419_Chip-Seq_LIVER_Mouse1.09408345
84EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.08707123
85CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08237673
86EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.07784414
87PU1_27457419_Chip-Seq_LIVER_Mouse1.07126160
88* P300_27268052_Chip-Seq_Bcells_Human1.07027794
89E2F1_18555785_Chip-Seq_ESCs_Mouse1.06927182
90NANOG_18555785_Chip-Seq_ESCs_Mouse1.06801585
91STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.05973954
92CMYC_18555785_Chip-Seq_ESCs_Mouse1.05374730
93GATA3_26560356_Chip-Seq_TH2_Human1.05029783
94SPI1_23127762_ChIP-Seq_K562_Human1.04764767
95SMRT_27268052_Chip-Seq_Bcells_Human1.03904533
96TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03600727
97PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.02071050
98KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.01934497
99ELF1_20517297_ChIP-Seq_JURKAT_Human1.00781805
100EGR1_19374776_ChIP-ChIP_THP-1_Human0.99745395
101P300_18555785_Chip-Seq_ESCs_Mouse0.99709898
102KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.98660206
103KDM2B_26808549_Chip-Seq_DND41_Human0.98621447
104OCT4_18555785_Chip-Seq_ESCs_Mouse0.98367471
105EGR1_23403033_ChIP-Seq_LIVER_Mouse0.97778205
106CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.97488082
107OCT4_21477851_ChIP-Seq_ESCs_Mouse0.96939006
108PU.1_20513432_ChIP-Seq_Bcells_Mouse0.96518399
109* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96146199
110RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.96092960
111CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96012508
112SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.95597281
113* NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.95556178
114ZFX_18555785_Chip-Seq_ESCs_Mouse0.95256443
115CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.95251584
116SOX2_18555785_Chip-Seq_ESCs_Mouse0.95027281
117CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94006989
118SMAD1_18555785_Chip-Seq_ESCs_Mouse0.93631968
119* MAF_26560356_Chip-Seq_TH1_Human0.92603012
120SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92555370
121PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92190471
122ER_23166858_ChIP-Seq_MCF-7_Human0.92126821
123ESRRB_18555785_Chip-Seq_ESCs_Mouse0.92012201
124TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.91727894
125NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.91569033
126CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91459087
127CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91412711
128RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.91392164
129STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.91057736
130GATA2_21666600_ChIP-Seq_HMVEC_Human0.90548271
131ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.89703937
132* SPI1_20517297_ChIP-Seq_HL60_Human0.89614827
133CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.89545946
134CRX_20693478_ChIP-Seq_RETINA_Mouse0.88907451
135GATA1_22383799_ChIP-Seq_G1ME_Mouse0.88842845
136GATA2_19941826_ChIP-Seq_K562_Human0.88806922
137BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.88429543
138VDR_21846776_ChIP-Seq_THP-1_Human0.88279212
139RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87279455
140SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.87270612
141E2F1_20622854_ChIP-Seq_HELA_Human0.83466753
142LXR_22292898_ChIP-Seq_THP-1_Human0.83233253

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.37941941
2MP0009785_altered_susceptibility_to3.41599641
3MP0005671_abnormal_response_to3.39665093
4MP0002148_abnormal_hypersensitivity_rea3.39612111
5MP0003436_decreased_susceptibility_to3.19917692
6MP0005000_abnormal_immune_tolerance3.19258448
7MP0005387_immune_system_phenotype3.06042305
8MP0001790_abnormal_immune_system3.06042305
9MP0002419_abnormal_innate_immunity2.96139839
10MP0003724_increased_susceptibility_to2.93443715
11MP0005025_abnormal_response_to2.84336135
12MP0001800_abnormal_humoral_immune2.79839843
13MP0002452_abnormal_antigen_presenting2.76779414
14MP0000685_abnormal_immune_system2.72713665
15MP0002723_abnormal_immune_serum2.67390207
16MP0006082_CNS_inflammation2.54701834
17MP0001819_abnormal_immune_cell2.44327488
18MP0002420_abnormal_adaptive_immunity2.44005140
19MP0003303_peritoneal_inflammation2.39258512
20MP0002405_respiratory_system_inflammati2.05966552
21MP0005174_abnormal_tail_pigmentation2.05922155
22MP0001853_heart_inflammation1.95950961
23MP0002277_abnormal_respiratory_mucosa1.95322952
24MP0004510_myositis1.94490123
25MP0009333_abnormal_splenocyte_physiolog1.87208793
26MP0000716_abnormal_immune_system1.85522462
27MP0003763_abnormal_thymus_physiology1.81753666
28MP0000015_abnormal_ear_pigmentation1.77427706
29MP0002398_abnormal_bone_marrow1.77355213
30MP0003136_yellow_coat_color1.73987870
31MP0005310_abnormal_salivary_gland1.72209786
32MP0005464_abnormal_platelet_physiology1.71598577
33MP0001845_abnormal_inflammatory_respons1.69309010
34MP0003300_gastrointestinal_ulcer1.68757214
35MP0001533_abnormal_skeleton_physiology1.60969293
36MP0006292_abnormal_olfactory_placode1.56674861
37MP0010155_abnormal_intestine_physiology1.52470961
38MP0002998_abnormal_bone_remodeling1.49514846
39MP0009764_decreased_sensitivity_to1.49001008
40MP0002396_abnormal_hematopoietic_system1.48184581
41MP0001986_abnormal_taste_sensitivity1.46088421
42MP0002429_abnormal_blood_cell1.44202186
43MP0004381_abnormal_hair_follicle1.42167606
44MP0000689_abnormal_spleen_morphology1.41665206
45MP0002006_tumorigenesis1.38059191
46MP0008004_abnormal_stomach_pH1.37184201
47MP0002933_joint_inflammation1.35777093
48MP0005167_abnormal_blood-brain_barrier1.33470773
49MP0002722_abnormal_immune_system1.32871074
50MP0003195_calcinosis1.31773345
51MP0003172_abnormal_lysosome_physiology1.26096842
52MP0002132_abnormal_respiratory_system1.26025875
53MP0008260_abnormal_autophagy1.25516474
54MP0005058_abnormal_lysosome_morphology1.23966130
55MP0008469_abnormal_protein_level1.23097579
56MP0003448_altered_tumor_morphology1.22896755
57MP0003646_muscle_fatigue1.21745060
58MP0004742_abnormal_vestibular_system1.21521827
59MP0001873_stomach_inflammation1.18429153
60MP0003183_abnormal_peptide_metabolism1.18345451
61MP0004947_skin_inflammation1.17343231
62MP0000465_gastrointestinal_hemorrhage1.15284530
63MP0009840_abnormal_foam_cell1.14545581
64MP0005409_darkened_coat_color1.12795784
65MP0002102_abnormal_ear_morphology1.10590086
66MP0005645_abnormal_hypothalamus_physiol1.09858618
67MP0003806_abnormal_nucleotide_metabolis1.08059991
68MP0005171_absent_coat_pigmentation1.07016409
69MP0003656_abnormal_erythrocyte_physiolo1.06162714
70MP0000858_altered_metastatic_potential1.05742377
71MP0000490_abnormal_crypts_of1.00199881
72MP0005075_abnormal_melanosome_morpholog1.00187671
73MP0000703_abnormal_thymus_morphology1.00155937
74MP0003045_fibrosis0.99355264
75MP0002095_abnormal_skin_pigmentation0.97923598
76MP0000569_abnormal_digit_pigmentation0.97610761
77MP0002166_altered_tumor_susceptibility0.96832464
78MP0001188_hyperpigmentation0.95380848
79MP0000343_altered_response_to0.94938169
80MP0001851_eye_inflammation0.93954444
81MP0005257_abnormal_intraocular_pressure0.93889530
82MP0005390_skeleton_phenotype0.93340536
83MP0000604_amyloidosis0.91738305
84MP0009763_increased_sensitivity_to0.90889869
85MP0008057_abnormal_DNA_replication0.89844963
86MP0009765_abnormal_xenobiotic_induced0.87869148
87MP0002332_abnormal_exercise_endurance0.87343106
88MP0003866_abnormal_defecation0.85621207
89MP0003828_pulmonary_edema0.83877644
90MP0001501_abnormal_sleep_pattern0.82930832
91MP0005451_abnormal_body_composition0.80340266
92MP0003191_abnormal_cellular_cholesterol0.79213433
93MP0000372_irregular_coat_pigmentation0.78413944
94MP0004782_abnormal_surfactant_physiolog0.75484800
95MP0003795_abnormal_bone_structure0.74955330
96MP0001663_abnormal_digestive_system0.74945564
97MP0002653_abnormal_ependyma_morphology0.74443981
98MP0008961_abnormal_basal_metabolism0.73665421
99MP0005397_hematopoietic_system_phenotyp0.73483631
100MP0001545_abnormal_hematopoietic_system0.73483631
101MP0005377_hearing/vestibular/ear_phenot0.72438241
102MP0003878_abnormal_ear_physiology0.72438241
103MP0004130_abnormal_muscle_cell0.72267407
104MP0004808_abnormal_hematopoietic_stem0.70848278
105MP0005164_abnormal_response_to0.69550314
106MP0010386_abnormal_urinary_bladder0.68170008
107MP0005166_decreased_susceptibility_to0.67086568
108MP0002138_abnormal_hepatobiliary_system0.66976686
109MP0000249_abnormal_blood_vessel0.66798183
110MP0000371_diluted_coat_color0.64390653
111MP0004043_abnormal_pH_regulation0.64097284
112MP0002638_abnormal_pupillary_reflex0.63924764
113MP0000920_abnormal_myelination0.63613010
114MP0000681_abnormal_thyroid_gland0.62120359
115MP0004883_abnormal_blood_vessel0.61851389
116MP0000566_synostosis0.60351928
117MP0003075_altered_response_to0.59520523
118MP0002693_abnormal_pancreas_physiology0.59486750
119MP0008058_abnormal_DNA_repair0.59332228
120MP0009278_abnormal_bone_marrow0.58500041
121MP0005379_endocrine/exocrine_gland_phen0.58424797
122MP0002254_reproductive_system_inflammat0.58337708
123MP0002163_abnormal_gland_morphology0.58017490
124MP0002019_abnormal_tumor_incidence0.56967975
125MP0005266_abnormal_metabolism0.55832064
126MP0006054_spinal_hemorrhage0.54604789

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.67841829
2Eczematoid dermatitis (HP:0000976)5.50185230
3Recurrent bacterial skin infections (HP:0005406)4.90802742
4Stomatitis (HP:0010280)4.30065890
5Mediastinal lymphadenopathy (HP:0100721)4.21127690
6Retrobulbar optic neuritis (HP:0100654)4.13012138
7Optic neuritis (HP:0100653)4.13012138
8Abnormality of macrophages (HP:0004311)4.10657285
9Chronic obstructive pulmonary disease (HP:0006510)4.09026577
10Obstructive lung disease (HP:0006536)4.09026577
11Myositis (HP:0100614)4.05148016
12Elevated erythrocyte sedimentation rate (HP:0003565)4.04107846
13Recurrent gram-negative bacterial infections (HP:0005420)4.00030102
14Orchitis (HP:0100796)3.67163034
15Recurrent fungal infections (HP:0002841)3.64947520
16Recurrent skin infections (HP:0001581)3.49442711
17Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.49419111
18Chronic otitis media (HP:0000389)3.36544322
19Recurrent cutaneous fungal infections (HP:0011370)3.35568134
20Chronic mucocutaneous candidiasis (HP:0002728)3.35568134
21Meningitis (HP:0001287)3.31426008
22Recurrent pneumonia (HP:0006532)3.29725164
23Vasculitis (HP:0002633)3.24266386
24Parakeratosis (HP:0001036)3.22221754
25Gingivitis (HP:0000230)3.12032175
26Recurrent viral infections (HP:0004429)2.98756561
27Vacuolated lymphocytes (HP:0001922)2.97262495
28Gastrointestinal infarctions (HP:0005244)2.82168642
29Chromosomal breakage induced by crosslinking agents (HP:0003221)2.81172502
30Agammaglobulinemia (HP:0004432)2.80969917
31Autoimmune hemolytic anemia (HP:0001890)2.79476312
32Prostate neoplasm (HP:0100787)2.77350042
33Cheilitis (HP:0100825)2.76849196
34Increased IgE level (HP:0003212)2.71312641
35Pulmonary infiltrates (HP:0002113)2.69264505
36Increased IgM level (HP:0003496)2.66051110
37Recurrent lower respiratory tract infections (HP:0002783)2.65065904
38Cellulitis (HP:0100658)2.60792347
39Basal ganglia calcification (HP:0002135)2.59721718
40Epistaxis (HP:0000421)2.59184783
41Chromsome breakage (HP:0040012)2.55155647
42Dysostosis multiplex (HP:0000943)2.51735606
43Increased serum ferritin (HP:0003281)2.44700532
44White forelock (HP:0002211)2.41640086
45Colitis (HP:0002583)2.40796067
46IgM deficiency (HP:0002850)2.39726216
47Recurrent sinusitis (HP:0011108)2.39630724
48Abnormal delayed hypersensitivity skin test (HP:0002963)2.39475782
49Chronic sinusitis (HP:0011109)2.39255533
50Chronic diarrhea (HP:0002028)2.38772174
51Hemoptysis (HP:0002105)2.38731476
52Abnormality of the prostate (HP:0008775)2.38270958
53Clumsiness (HP:0002312)2.36916950
54Lymphopenia (HP:0001888)2.35891303
55Patchy hypopigmentation of hair (HP:0011365)2.33908490
56Purpura (HP:0000979)2.30833468
57Keratoconjunctivitis sicca (HP:0001097)2.29254432
58Chest pain (HP:0100749)2.28371962
59Osteomyelitis (HP:0002754)2.27755235
60Urticaria (HP:0001025)2.25938302
61Abnormality of T cell number (HP:0011839)2.23628381
62Abnormality of cells of the lymphoid lineage (HP:0012140)2.21655218
63Panhypogammaglobulinemia (HP:0003139)2.21150508
64Anorexia (HP:0002039)2.20769457
65T lymphocytopenia (HP:0005403)2.19867503
66Abnormality of iron homeostasis (HP:0011031)2.19853759
67Petechiae (HP:0000967)2.18791482
68Leukocytosis (HP:0001974)2.16008288
69Keratoconjunctivitis (HP:0001096)2.15339549
70Pulmonary embolism (HP:0002204)2.15046292
71Inflammation of the large intestine (HP:0002037)2.13522162
72Episodic fever (HP:0001954)2.11711842
73Recurrent bronchitis (HP:0002837)2.11592154
74Autoimmune thrombocytopenia (HP:0001973)2.09529613
75IgG deficiency (HP:0004315)2.09409323
76Attenuation of retinal blood vessels (HP:0007843)2.09109547
77Abnormality of transition element cation homeostasis (HP:0011030)2.08583994
78Gastrointestinal stroma tumor (HP:0100723)2.08262971
79Encephalitis (HP:0002383)2.08227763
80Keratitis (HP:0000491)2.06298971
81Congenital stationary night blindness (HP:0007642)2.04741995
82Duplicated collecting system (HP:0000081)2.02646206
83Eosinophilia (HP:0001880)2.02627628
84IgA deficiency (HP:0002720)2.02266002
85Stomach cancer (HP:0012126)2.01217981
86Abnormality of T cells (HP:0002843)2.00577697
87Nasal polyposis (HP:0100582)2.00107726
88Hypochromic anemia (HP:0001931)1.98538660
89Hematochezia (HP:0002573)1.98068373
90Abnormality of the renal collecting system (HP:0004742)1.96889521
91Pustule (HP:0200039)1.96431432
92Abnormality of DNA repair (HP:0003254)1.94191829
93Increased neuronal autofluorescent lipopigment (HP:0002074)1.93998076
94Thyroiditis (HP:0100646)1.93972719
95Hypergammaglobulinemia (HP:0010702)1.93778773
96Absent rod-and cone-mediated responses on ERG (HP:0007688)1.93644693
97Abnormality of glycolipid metabolism (HP:0010969)1.92532599
98Abnormality of liposaccharide metabolism (HP:0010968)1.92532599
99Abnormality of glycosphingolipid metabolism (HP:0004343)1.92532599
100B lymphocytopenia (HP:0010976)1.92404135
101Abnormality of B cell number (HP:0010975)1.92404135
102Vertigo (HP:0002321)1.92305210
103Polyneuropathy (HP:0001271)1.92257229
104Periodontitis (HP:0000704)1.91090283
105Genetic anticipation (HP:0003743)1.90805667
106Albinism (HP:0001022)1.90619714
107Dynein arm defect of respiratory motile cilia (HP:0012255)1.90314300
108Absent/shortened dynein arms (HP:0200106)1.90314300
109Arterial thrombosis (HP:0004420)1.90124543
110Gastrointestinal inflammation (HP:0004386)1.85105002
111Clubbing of toes (HP:0100760)1.84366038
112Sepsis (HP:0100806)1.83049222
113Abnormality of T cell physiology (HP:0011840)1.82716100
114Abnormality of eosinophils (HP:0001879)1.81876951
115Conical tooth (HP:0000698)1.80851987
116Gingival bleeding (HP:0000225)1.79914301
117Prolonged bleeding time (HP:0003010)1.76315939
118Bone pain (HP:0002653)1.75860980
119Spontaneous hematomas (HP:0007420)1.75122837
120Neutropenia (HP:0001875)1.73109620
121Granulocytopenia (HP:0001913)1.72717638
122Glomerulopathy (HP:0100820)1.71031401
123Abnormality of the pleura (HP:0002103)1.70667564
124Increased cerebral lipofuscin (HP:0011813)1.70640284
125Gangrene (HP:0100758)1.70545956
126Reduced antithrombin III activity (HP:0001976)1.69907085
127Arthralgia (HP:0002829)1.69228944

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K144.07579826
2BLK3.81695820
3IRAK43.51231782
4TXK3.44429252
5IRAK33.21607528
6FRK3.15304713
7MAP4K12.99608598
8SIK32.92705995
9RIPK42.68847894
10IKBKE2.30293683
11TBK12.24175970
12IKBKB2.21419478
13PBK2.13416868
14JAK32.12011230
15KIT2.11191522
16TNIK2.03178512
17TEC1.91019818
18MAP3K111.89668205
19ACVR1B1.84650519
20SIK21.81939443
21TYK21.72881395
22NME21.68762487
23MAP3K131.68320349
24BTK1.51892104
25SYK1.50079700
26CASK1.48889720
27EIF2AK21.45200295
28STK161.38628258
29FES1.37272995
30ADRBK21.34857212
31ZAP701.33583996
32MKNK21.32748934
33BMPR21.29190370
34CHUK1.25908988
35CLK11.25735871
36MARK31.25690379
37IRAK11.25637586
38LYN1.25619933
39MUSK1.20274756
40LCK1.18628054
41TESK21.18424884
42HCK1.13958131
43CSK1.13559660
44TAOK31.13517060
45YES11.13458232
46CSF1R1.12160446
47PIM21.09633779
48ITK1.09327000
49NLK1.08297115
50BMPR1B1.06321534
51JAK11.06250630
52DAPK21.04541425
53EIF2AK31.03341682
54IRAK21.03130235
55MST40.93445667
56PIM10.93105403
57GRK70.91806629
58MAP3K30.88259782
59TAOK20.87738327
60TAOK10.82628334
61NUAK10.81799578
62EPHB10.79471756
63FGR0.78598216
64MKNK10.76337043
65TGFBR20.76320578
66PKN10.75356004
67MAP2K60.74685620
68MAP3K10.73918525
69CDK80.73103207
70PRPF4B0.72743708
71CDC42BPA0.71685384
72INSRR0.70704653
73ZAK0.69286958
74PDK10.69252965
75STK40.69228691
76PRKCQ0.69001196
77PIK3CG0.67190956
78MAPK110.64532892
79BCKDK0.64395382
80EPHA30.60328879
81ADRBK10.60263397
82GRK10.59849072
83CDK190.58477532
84RPS6KA40.58114802
85TRPM70.56829949
86MAP3K70.56066296
87TNK20.55652717
88TLK10.55434383
89MAPK120.54087607
90CDK30.53260643
91STK100.51371070
92PDPK10.50660144
93CAMKK20.50411823
94PTK2B0.49180458
95MAPK70.48572949
96ABL10.48374331
97PRKD20.47425106
98RPS6KA50.47296244
99PRKCD0.46767503
100TGFBR10.45718536
101SRPK10.45412474
102MARK20.43526592
103KDR0.42407613
104RPS6KC10.41423604
105RPS6KL10.41423604
106FLT30.40801094
107BRD40.39177287
108CDK40.37544725
109MST1R0.36698050
110ABL20.36066209
111MAPKAPK30.35857594
112SIK10.35785787
113PRKAA20.33630244
114MAPK130.32404963
115JAK20.30975684
116MAP3K50.29862340
117VRK10.28704264
118HIPK20.27885557
119MAP2K20.26873661
120MAPK30.26763617
121NEK90.26090371
122MATK0.25940793
123MAP3K120.24986910
124CDK90.24800628
125MAPK150.24399654
126MAPKAPK20.23493665
127FYN0.23408375
128ERN10.22433999
129NEK60.21809681
130RPS6KA60.21538705
131GRK60.21025596
132MAP2K30.19215939
133INSR0.18995666
134BMX0.18759755
135MAPK40.18701792

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053322.99187257
2Allograft rejection_Homo sapiens_hsa053302.87527972
3NF-kappa B signaling pathway_Homo sapiens_hsa040642.86504954
4Leishmaniasis_Homo sapiens_hsa051402.67355245
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.62768146
6Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.56585396
7Primary immunodeficiency_Homo sapiens_hsa053402.44807789
8Intestinal immune network for IgA production_Homo sapiens_hsa046722.31284387
9Toll-like receptor signaling pathway_Homo sapiens_hsa046202.26417212
10Asthma_Homo sapiens_hsa053102.20151354
11Measles_Homo sapiens_hsa051622.12766203
12NOD-like receptor signaling pathway_Homo sapiens_hsa046212.06209433
13Hematopoietic cell lineage_Homo sapiens_hsa046402.05818673
14Osteoclast differentiation_Homo sapiens_hsa043802.04528075
15RIG-I-like receptor signaling pathway_Homo sapiens_hsa046222.02135450
16Rheumatoid arthritis_Homo sapiens_hsa053232.00753091
17Malaria_Homo sapiens_hsa051441.96908939
18Autoimmune thyroid disease_Homo sapiens_hsa053201.86570333
19Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.77623943
20Tuberculosis_Homo sapiens_hsa051521.67604644
21Type I diabetes mellitus_Homo sapiens_hsa049401.65309033
22B cell receptor signaling pathway_Homo sapiens_hsa046621.62362001
23Pertussis_Homo sapiens_hsa051331.60155280
24Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.60087274
25Staphylococcus aureus infection_Homo sapiens_hsa051501.55339132
26Legionellosis_Homo sapiens_hsa051341.54275881
27Herpes simplex infection_Homo sapiens_hsa051681.50929955
28Other glycan degradation_Homo sapiens_hsa005111.50245189
29TNF signaling pathway_Homo sapiens_hsa046681.45433317
30Jak-STAT signaling pathway_Homo sapiens_hsa046301.42903068
31T cell receptor signaling pathway_Homo sapiens_hsa046601.42833755
32African trypanosomiasis_Homo sapiens_hsa051431.42020302
33Influenza A_Homo sapiens_hsa051641.36307954
34Chemokine signaling pathway_Homo sapiens_hsa040621.21223516
35Phagosome_Homo sapiens_hsa041451.18151861
36Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.16958650
37Salmonella infection_Homo sapiens_hsa051321.13252931
38Antigen processing and presentation_Homo sapiens_hsa046121.13114242
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.09690765
40Lysosome_Homo sapiens_hsa041421.09346693
41Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.08716441
42Toxoplasmosis_Homo sapiens_hsa051451.08453981
43Glycosaminoglycan degradation_Homo sapiens_hsa005311.06803338
44Apoptosis_Homo sapiens_hsa042101.04793086
45SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99544863
46Shigellosis_Homo sapiens_hsa051310.93995349
47Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.92338826
48Hepatitis B_Homo sapiens_hsa051610.91213403
49Sphingolipid metabolism_Homo sapiens_hsa006000.88439858
50Transcriptional misregulation in cancer_Homo sapiens_hsa052020.88062383
51Non-homologous end-joining_Homo sapiens_hsa034500.88031715
52Homologous recombination_Homo sapiens_hsa034400.84734883
53Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.84235214
54Fanconi anemia pathway_Homo sapiens_hsa034600.83145736
55Protein export_Homo sapiens_hsa030600.79081256
56Acute myeloid leukemia_Homo sapiens_hsa052210.77187293
57Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.76930492
58Hepatitis C_Homo sapiens_hsa051600.76888900
59alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.75079665
60Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.74197154
61Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.72322881
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70880887
63Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70589555
64Leukocyte transendothelial migration_Homo sapiens_hsa046700.67996542
65Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63328754
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.62622193
67AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61132722
68Adipocytokine signaling pathway_Homo sapiens_hsa049200.60924242
69Viral myocarditis_Homo sapiens_hsa054160.60468819
70Epstein-Barr virus infection_Homo sapiens_hsa051690.59333899
71Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.53626900
72ABC transporters_Homo sapiens_hsa020100.52859224
73Ribosome_Homo sapiens_hsa030100.51091820
74Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.49283716
75Dorso-ventral axis formation_Homo sapiens_hsa043200.48478456
76VEGF signaling pathway_Homo sapiens_hsa043700.48236048
77Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.47796133
78Basal transcription factors_Homo sapiens_hsa030220.45616785
79Linoleic acid metabolism_Homo sapiens_hsa005910.45232888
80Collecting duct acid secretion_Homo sapiens_hsa049660.44287372
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44164337
82Arachidonic acid metabolism_Homo sapiens_hsa005900.43141778
83Prolactin signaling pathway_Homo sapiens_hsa049170.42934739
84Mineral absorption_Homo sapiens_hsa049780.42019574
85Tryptophan metabolism_Homo sapiens_hsa003800.41889933
86HTLV-I infection_Homo sapiens_hsa051660.40823371
87Type II diabetes mellitus_Homo sapiens_hsa049300.38379929
88Pancreatic cancer_Homo sapiens_hsa052120.38374948
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.37535000
90Platelet activation_Homo sapiens_hsa046110.36392449
91Ether lipid metabolism_Homo sapiens_hsa005650.36177028
92Sphingolipid signaling pathway_Homo sapiens_hsa040710.35287847
93Base excision repair_Homo sapiens_hsa034100.34742108
94Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.32892053
95Chronic myeloid leukemia_Homo sapiens_hsa052200.32813890
96Glycerophospholipid metabolism_Homo sapiens_hsa005640.32037169
97Insulin resistance_Homo sapiens_hsa049310.29897050
98Glycerolipid metabolism_Homo sapiens_hsa005610.29654360
99DNA replication_Homo sapiens_hsa030300.27686773
100RNA polymerase_Homo sapiens_hsa030200.27513165
101Amoebiasis_Homo sapiens_hsa051460.26756859
102MAPK signaling pathway_Homo sapiens_hsa040100.26571891
103Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.26165060
104Small cell lung cancer_Homo sapiens_hsa052220.24795984
105Regulation of actin cytoskeleton_Homo sapiens_hsa048100.24576586
106Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.24358085
107Phototransduction_Homo sapiens_hsa047440.24230114
108FoxO signaling pathway_Homo sapiens_hsa040680.24200067
109Notch signaling pathway_Homo sapiens_hsa043300.24170134
110Viral carcinogenesis_Homo sapiens_hsa052030.23743512
111Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.23713210
112p53 signaling pathway_Homo sapiens_hsa041150.23470334
113Non-small cell lung cancer_Homo sapiens_hsa052230.23220059
114Regulation of autophagy_Homo sapiens_hsa041400.23053224
115Systemic lupus erythematosus_Homo sapiens_hsa053220.22973557
116Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.22944573
117Melanoma_Homo sapiens_hsa052180.22341331
118Pyrimidine metabolism_Homo sapiens_hsa002400.21180162
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.21163233
120Phospholipase D signaling pathway_Homo sapiens_hsa040720.20079990
121Nitrogen metabolism_Homo sapiens_hsa009100.19620941
122Ovarian steroidogenesis_Homo sapiens_hsa049130.18935389
123Bladder cancer_Homo sapiens_hsa052190.18639306

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