RIMBP2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)6.10217209
2negative regulation of macroautophagy (GO:0016242)6.07330760
3auditory receptor cell stereocilium organization (GO:0060088)5.53715867
4detection of molecule of bacterial origin (GO:0032490)5.48947427
5post-embryonic morphogenesis (GO:0009886)4.97242163
6positive regulation of neurotransmitter secretion (GO:0001956)4.83922724
7vocalization behavior (GO:0071625)4.79470275
8positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.72793245
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.67561580
10positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)4.36790719
11regulation of synaptic vesicle exocytosis (GO:2000300)4.27065856
12regulation of glutamate receptor signaling pathway (GO:1900449)4.21474654
13energy homeostasis (GO:0097009)4.20929290
14regulation of short-term neuronal synaptic plasticity (GO:0048172)4.16452923
15cellular anion homeostasis (GO:0030002)4.15595059
16locomotory exploration behavior (GO:0035641)4.14109344
17positive regulation of neurological system process (GO:0031646)4.12094726
18positive regulation of neurotransmitter transport (GO:0051590)4.03661427
19synaptic vesicle maturation (GO:0016188)4.02251693
20presynaptic membrane assembly (GO:0097105)3.84601885
21negative regulation of meiosis (GO:0045835)3.84418633
22presynaptic membrane organization (GO:0097090)3.84387910
23inner ear receptor stereocilium organization (GO:0060122)3.76661005
24sulfate transmembrane transport (GO:1902358)3.75606892
25neuron remodeling (GO:0016322)3.74785504
26neurotransmitter transport (GO:0006836)3.74658863
27ionotropic glutamate receptor signaling pathway (GO:0035235)3.71984160
28insulin secretion (GO:0030073)3.68463684
29positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.65079210
30regulation of synaptic vesicle transport (GO:1902803)3.58173274
31positive regulation of synapse maturation (GO:0090129)3.57153052
32cellular potassium ion homeostasis (GO:0030007)3.56611285
33negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.54702439
34positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.54334268
35lateral ventricle development (GO:0021670)3.49531495
36regulation of neurotransmitter levels (GO:0001505)3.45126663
37proline transport (GO:0015824)3.41853947
38trivalent inorganic anion homeostasis (GO:0072506)3.41068623
39phosphate ion homeostasis (GO:0055062)3.41068623
40regulation of vesicle fusion (GO:0031338)3.38924896
41detection of external biotic stimulus (GO:0098581)3.36503917
42negative regulation of dendrite morphogenesis (GO:0050774)3.33286871
43gamma-aminobutyric acid transport (GO:0015812)3.32625145
44synaptic transmission, glutamatergic (GO:0035249)3.28275628
45axonal fasciculation (GO:0007413)3.28135543
46chemosensory behavior (GO:0007635)3.28081025
47serotonin metabolic process (GO:0042428)3.27782222
48positive regulation of synaptic transmission, GABAergic (GO:0032230)3.27551953
49regulation of calcium ion-dependent exocytosis (GO:0017158)3.25909647
50glycine transport (GO:0015816)3.24848335
51negative regulation of cytosolic calcium ion concentration (GO:0051481)3.19838927
52postsynaptic membrane organization (GO:0001941)3.19563933
53regulation of synapse structural plasticity (GO:0051823)3.18688431
54bicarbonate transport (GO:0015701)3.16500418
55positive regulation of membrane potential (GO:0045838)3.14686341
56startle response (GO:0001964)3.12743147
57auditory behavior (GO:0031223)3.10256143
58regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.09520913
59long term synaptic depression (GO:0060292)3.07679627
60positive regulation of CREB transcription factor activity (GO:0032793)3.02985229
61signal release (GO:0023061)3.02965390
62dendritic spine morphogenesis (GO:0060997)3.02839365
63dendritic spine organization (GO:0097061)3.02587146
64sulfate transport (GO:0008272)3.01288352
65primary amino compound metabolic process (GO:1901160)3.00191456
66glutamate receptor signaling pathway (GO:0007215)3.00108636
67regulation of dendritic spine morphogenesis (GO:0061001)3.00101826
68neuronal ion channel clustering (GO:0045161)2.97959575
69inositol metabolic process (GO:0006020)2.97804167
70positive regulation of dendritic spine development (GO:0060999)2.97577544
71detection of calcium ion (GO:0005513)2.95416036
72regulation of synapse maturation (GO:0090128)2.95294364
73neuron recognition (GO:0008038)2.94844343
74neuromuscular synaptic transmission (GO:0007274)2.94681446
75negative regulation of response to extracellular stimulus (GO:0032105)2.94247550
76negative regulation of response to nutrient levels (GO:0032108)2.94247550
77synaptic vesicle exocytosis (GO:0016079)2.94021919
78potassium ion homeostasis (GO:0055075)2.93996225
79regulation of dendritic spine development (GO:0060998)2.93574538
80regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.93422443
81glutamate secretion (GO:0014047)2.93147262
82neuromuscular process controlling posture (GO:0050884)2.92026027
83neuron-neuron synaptic transmission (GO:0007270)2.90386113
84positive regulation of vascular permeability (GO:0043117)2.89455921
85exploration behavior (GO:0035640)2.88585659
86transmission of nerve impulse (GO:0019226)2.88501443
87righting reflex (GO:0060013)2.88488962
88exogenous drug catabolic process (GO:0042738)2.88301663
89calcium ion-dependent exocytosis (GO:0017156)2.88210288
90glycoside metabolic process (GO:0016137)2.87774169
91response to dietary excess (GO:0002021)2.87275105
92prostate gland growth (GO:0060736)2.86949209
93synaptic transmission (GO:0007268)2.85492335
94glycerophospholipid catabolic process (GO:0046475)2.85075581
95protein localization to synapse (GO:0035418)2.84942069
96regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.84726729
97regulation of neurotransmitter secretion (GO:0046928)2.84200085
98negative regulation of dendrite development (GO:2000171)2.83609395
99positive regulation of hormone biosynthetic process (GO:0046886)2.82077025
100regulation of type B pancreatic cell apoptotic process (GO:2000674)2.81733842
101regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.81569162
102innervation (GO:0060384)2.81388545
103vesicle transport along microtubule (GO:0047496)2.81037999
104membrane depolarization (GO:0051899)2.80585707
105inositol phosphate catabolic process (GO:0071545)2.80552764
106regulation of neuronal synaptic plasticity (GO:0048168)2.78658399
107positive regulation of dendritic spine morphogenesis (GO:0061003)2.77365646
108neuron cell-cell adhesion (GO:0007158)2.77189959
109peptidyl-lysine dimethylation (GO:0018027)2.76603747
110regulation of long-term neuronal synaptic plasticity (GO:0048169)2.76579481
111glycosphingolipid biosynthetic process (GO:0006688)2.76059914
112response to pheromone (GO:0019236)2.75777685
113cerebellar granule cell differentiation (GO:0021707)2.75158763
114neurotransmitter secretion (GO:0007269)2.74878251
115regulation of excitatory postsynaptic membrane potential (GO:0060079)2.73488602
116pigment granule transport (GO:0051904)2.73287140
117catecholamine transport (GO:0051937)2.73087072
118pigment granule localization (GO:0051875)2.72933934
119cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.72270267
120detection of biotic stimulus (GO:0009595)2.72159859
121regulation of neurotransmitter transport (GO:0051588)2.70559368
122regulation of uterine smooth muscle contraction (GO:0070472)2.69124053
123brain morphogenesis (GO:0048854)2.68636563
124regulation of postsynaptic membrane potential (GO:0060078)2.67615104
125potassium ion transmembrane transport (GO:0071805)2.67293896
126cellular potassium ion transport (GO:0071804)2.67293896
127establishment of pigment granule localization (GO:0051905)2.67131958
128long-term synaptic potentiation (GO:0060291)2.66752611
129prepulse inhibition (GO:0060134)2.66274068
130synapse assembly (GO:0007416)2.66072676
131regulation of exocytosis (GO:0017157)2.66009566
132potassium ion import (GO:0010107)2.66004413
133intraspecies interaction between organisms (GO:0051703)2.64653591
134regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.64040355
135negative regulation of meiotic cell cycle (GO:0051447)2.57921842
136regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022352.57542276
137G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.57041315
138gamma-aminobutyric acid signaling pathway (GO:0007214)2.56583358
139regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.55288812
140drinking behavior (GO:0042756)2.55275096
141neurotransmitter-gated ion channel clustering (GO:0072578)2.52329975
142negative regulation of synaptic transmission, GABAergic (GO:0032229)2.51852619
143membrane hyperpolarization (GO:0060081)2.51209636
144neuronal action potential propagation (GO:0019227)2.48437120
145membrane depolarization during action potential (GO:0086010)2.48287113
146membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.48183350
147negative regulation of neurotransmitter transport (GO:0051589)2.47772613
148regulation of synaptic transmission, glutamatergic (GO:0051966)2.46253892
149opioid receptor signaling pathway (GO:0038003)2.45236261
150positive regulation of uterine smooth muscle contraction (GO:0070474)2.45064237
151regulation of synaptic plasticity (GO:0048167)2.43678223
152synaptic vesicle endocytosis (GO:0048488)2.41765750
153daunorubicin metabolic process (GO:0044597)15.9764155
154polyketide metabolic process (GO:0030638)15.9764155
155doxorubicin metabolic process (GO:0044598)15.9764155
156aminoglycoside antibiotic metabolic process (GO:0030647)10.3970000

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.19860015
2GBX2_23144817_ChIP-Seq_PC3_Human3.66941066
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.11178928
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.98456137
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.87489613
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.82071424
7EZH2_18974828_ChIP-Seq_MESCs_Mouse2.74520922
8RNF2_18974828_ChIP-Seq_MESCs_Mouse2.74520922
9DROSHA_22980978_ChIP-Seq_HELA_Human2.58204702
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.58047819
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.56163304
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.55579797
13* REST_21632747_ChIP-Seq_MESCs_Mouse2.45344694
14SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.44167266
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.37063446
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.31130112
17SUZ12_27294783_Chip-Seq_ESCs_Mouse2.29061820
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.24393252
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.23968513
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.22775371
21EZH2_27294783_Chip-Seq_ESCs_Mouse2.21693249
22GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.12214468
23GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.02442857
24* RARB_27405468_Chip-Seq_BRAIN_Mouse1.73910590
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70362600
26REST_18959480_ChIP-ChIP_MESCs_Mouse1.63882072
27EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.61572491
28SMAD3_21741376_ChIP-Seq_EPCs_Human1.58542965
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.57425647
30ERG_21242973_ChIP-ChIP_JURKAT_Human1.54572978
31CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.54272844
32P300_19829295_ChIP-Seq_ESCs_Human1.53500931
33SMAD4_21799915_ChIP-Seq_A2780_Human1.50127103
34RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.49249597
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.48918793
36IKZF1_21737484_ChIP-ChIP_HCT116_Human1.47979415
37BMI1_23680149_ChIP-Seq_NPCS_Mouse1.46689202
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.45608247
39RING1B_27294783_Chip-Seq_ESCs_Mouse1.42677094
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.42656948
41ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.41216889
42ZFP57_27257070_Chip-Seq_ESCs_Mouse1.37697744
43VDR_22108803_ChIP-Seq_LS180_Human1.37561753
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.36473705
45SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.34110522
46FUS_26573619_Chip-Seq_HEK293_Human1.33737057
47PIAS1_25552417_ChIP-Seq_VCAP_Human1.33069882
48CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.32587059
49BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.29701681
50IGF1R_20145208_ChIP-Seq_DFB_Human1.24169215
51* RXR_22108803_ChIP-Seq_LS180_Human1.23480219
52* STAT3_23295773_ChIP-Seq_U87_Human1.22387651
53RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.21219774
54TAF15_26573619_Chip-Seq_HEK293_Human1.20984452
55* AR_25329375_ChIP-Seq_VCAP_Human1.20930683
56FLI1_27457419_Chip-Seq_LIVER_Mouse1.20071216
57CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17793211
58NR3C1_21868756_ChIP-Seq_MCF10A_Human1.17780112
59ZNF217_24962896_ChIP-Seq_MCF-7_Human1.16638448
60TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.16142444
61TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15741551
62RNF2_27304074_Chip-Seq_NSC_Mouse1.15583341
63WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15495826
64HTT_18923047_ChIP-ChIP_STHdh_Human1.14962960
65RING1B_27294783_Chip-Seq_NPCs_Mouse1.14190423
66CDX2_19796622_ChIP-Seq_MESCs_Mouse1.13740523
67* TCF4_23295773_ChIP-Seq_U87_Human1.11096593
68* SOX2_21211035_ChIP-Seq_LN229_Gbm1.10354363
69CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10177045
70AR_19668381_ChIP-Seq_PC3_Human1.09843160
71YAP1_20516196_ChIP-Seq_MESCs_Mouse1.09267658
72* NR3C1_23031785_ChIP-Seq_PC12_Mouse1.09050835
73* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.09023557
74ZNF274_21170338_ChIP-Seq_K562_Hela1.07371670
75AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.06793905
76TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.06621204
77* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.06111723
78* RUNX2_22187159_ChIP-Seq_PCA_Human1.05975329
79BCAT_22108803_ChIP-Seq_LS180_Human1.05933170
80SMAD4_21741376_ChIP-Seq_HESCs_Human1.05395371
81MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.05138422
82TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05053089
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04687658
84AR_21572438_ChIP-Seq_LNCaP_Human1.04251181
85LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03807757
86UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03476504
87POU3F2_20337985_ChIP-ChIP_501MEL_Human1.02206600
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.02047244
89PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01575260
90VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.01068281
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.00260864
92* TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99361005
93RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99078147
94SMAD3_21741376_ChIP-Seq_HESCs_Human0.98933091
95SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97715559
96E2F1_18555785_Chip-Seq_ESCs_Mouse0.97098339
97CBP_20019798_ChIP-Seq_JUKART_Human0.96165544
98IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96165544
99SUZ12_18555785_Chip-Seq_ESCs_Mouse0.94804339
100EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.94759543
101EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.94444995
102ER_23166858_ChIP-Seq_MCF-7_Human0.93953531
103PCGF2_27294783_Chip-Seq_ESCs_Mouse0.93811645
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.93252980
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.93252980
106TCF4_22108803_ChIP-Seq_LS180_Human0.93182857
107STAT3_18555785_Chip-Seq_ESCs_Mouse0.93019472
108* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.90955854
109ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.90908035
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.90080997
111MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89943257
112* SMAD3_21741376_ChIP-Seq_ESCs_Human0.89767703
113PRDM14_20953172_ChIP-Seq_ESCs_Human0.89701785
114NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.89458665
115SUZ12_27294783_Chip-Seq_NPCs_Mouse0.88901973
116P53_22387025_ChIP-Seq_ESCs_Mouse0.88779066
117TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87232252
118CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.86979659
119EP300_21415370_ChIP-Seq_HL-1_Mouse0.86974390
120CMYC_18555785_Chip-Seq_ESCs_Mouse0.86847523

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005377_hearing/vestibular/ear_phenot4.96805362
2MP0003878_abnormal_ear_physiology4.96805362
3MP0008004_abnormal_stomach_pH4.61659766
4MP0004859_abnormal_synaptic_plasticity4.55161908
5MP0005645_abnormal_hypothalamus_physiol3.78723647
6MP0003879_abnormal_hair_cell3.72467753
7MP0003880_abnormal_central_pattern3.41687344
8MP0005423_abnormal_somatic_nervous3.22531765
9MP0000678_abnormal_parathyroid_gland3.16199882
10MP0003635_abnormal_synaptic_transmissio2.81923625
11MP0001486_abnormal_startle_reflex2.53428338
12MP0009745_abnormal_behavioral_response2.46361227
13MP0001485_abnormal_pinna_reflex2.33175699
14MP0002572_abnormal_emotion/affect_behav2.30805614
15MP0006276_abnormal_autonomic_nervous2.25093323
16MP0009046_muscle_twitch2.23392438
17MP0004270_analgesia2.23239945
18MP0005646_abnormal_pituitary_gland2.22457980
19MP0002064_seizures2.17279936
20MP0002063_abnormal_learning/memory/cond2.10625847
21MP0001968_abnormal_touch/_nociception2.10424306
22MP0002272_abnormal_nervous_system2.07930337
23MP0001501_abnormal_sleep_pattern2.07807164
24MP0004742_abnormal_vestibular_system2.06851141
25MP0006292_abnormal_olfactory_placode1.98788338
26MP0001986_abnormal_taste_sensitivity1.98442865
27MP0002735_abnormal_chemical_nociception1.96899639
28MP0009780_abnormal_chondrocyte_physiolo1.91824625
29MP0002837_dystrophic_cardiac_calcinosis1.82786647
30MP0008877_abnormal_DNA_methylation1.82760525
31MP0001440_abnormal_grooming_behavior1.81177020
32MP0002734_abnormal_mechanical_nocicepti1.80523990
33MP0002557_abnormal_social/conspecific_i1.80381810
34MP0004858_abnormal_nervous_system1.79551434
35MP0003123_paternal_imprinting1.70823067
36MP0002909_abnormal_adrenal_gland1.66846186
37MP0010386_abnormal_urinary_bladder1.65050121
38MP0002184_abnormal_innervation1.62452221
39MP0001905_abnormal_dopamine_level1.59618243
40MP0002822_catalepsy1.59097581
41MP0005386_behavior/neurological_phenoty1.58504997
42MP0004924_abnormal_behavior1.58504997
43MP0009697_abnormal_copulation1.58131058
44MP0001970_abnormal_pain_threshold1.48616015
45MP0004043_abnormal_pH_regulation1.47851887
46MP0002733_abnormal_thermal_nociception1.44887868
47MP0002736_abnormal_nociception_after1.41538124
48MP0003121_genomic_imprinting1.40309758
49MP0006072_abnormal_retinal_apoptosis1.37603378
50MP0002067_abnormal_sensory_capabilities1.33579935
51MP0002638_abnormal_pupillary_reflex1.29002861
52MP0005551_abnormal_eye_electrophysiolog1.25463745
53MP0001664_abnormal_digestion1.24336206
54MP0001502_abnormal_circadian_rhythm1.22552398
55MP0002876_abnormal_thyroid_physiology1.22285967
56MP0004811_abnormal_neuron_physiology1.17694139
57MP0002693_abnormal_pancreas_physiology1.15529090
58MP0003646_muscle_fatigue1.13406290
59MP0003045_fibrosis1.12011784
60MP0003283_abnormal_digestive_organ1.09500752
61MP0004885_abnormal_endolymph1.08711699
62MP0003195_calcinosis1.08037120
63MP0005379_endocrine/exocrine_gland_phen1.06167229
64MP0001529_abnormal_vocalization1.05657162
65MP0000013_abnormal_adipose_tissue1.05229927
66MP0003329_amyloid_beta_deposits1.03410712
67MP0010234_abnormal_vibrissa_follicle1.01555201
68MP0000955_abnormal_spinal_cord1.00963256
69MP0002066_abnormal_motor_capabilities/c0.96033709
70MP0000778_abnormal_nervous_system0.93489068
71MP0001963_abnormal_hearing_physiology0.93434751
72MP0008874_decreased_physiological_sensi0.93343536
73MP0003941_abnormal_skin_development0.90377776
74MP0000631_abnormal_neuroendocrine_gland0.89672362
75MP0004085_abnormal_heartbeat0.88150536
76MP0008872_abnormal_physiological_respon0.88059035
77MP0008569_lethality_at_weaning0.87550516
78MP0003633_abnormal_nervous_system0.86516800
79MP0002069_abnormal_eating/drinking_beha0.86241657
80MP0003868_abnormal_feces_composition0.86159157
81MP0005253_abnormal_eye_physiology0.83907297
82MP0005167_abnormal_blood-brain_barrier0.83856380
83MP0000681_abnormal_thyroid_gland0.83232725
84MP0002882_abnormal_neuron_morphology0.81223142
85MP0003690_abnormal_glial_cell0.80433772
86MP0001765_abnormal_ion_homeostasis0.80275728
87MP0001984_abnormal_olfaction0.80214548
88MP0002928_abnormal_bile_duct0.79679059
89MP0001944_abnormal_pancreas_morphology0.79277287
90MP0000566_synostosis0.79178595
91MP0004147_increased_porphyrin_level0.77130585
92MP0005448_abnormal_energy_balance0.74828255
93MP0000569_abnormal_digit_pigmentation0.73806610
94MP0004133_heterotaxia0.73636309
95MP0005220_abnormal_exocrine_pancreas0.73621401
96MP0001756_abnormal_urination0.73522750
97MP0005310_abnormal_salivary_gland0.71522374
98MP0002752_abnormal_somatic_nervous0.70903697
99MP0003122_maternal_imprinting0.69758913
100MP0002751_abnormal_autonomic_nervous0.68778468
101MP0000639_abnormal_adrenal_gland0.68629256
102MP0003787_abnormal_imprinting0.68235059
103MP0003075_altered_response_to0.66326561
104MP0000920_abnormal_myelination0.66124508
105MP0003632_abnormal_nervous_system0.66100596
106MP0002229_neurodegeneration0.66019907
107MP0002163_abnormal_gland_morphology0.66017322
108MP0002078_abnormal_glucose_homeostasis0.65293686
109MP0008961_abnormal_basal_metabolism0.65002468
110MP0003634_abnormal_glial_cell0.63944623
111MP0002090_abnormal_vision0.62749177
112MP0002877_abnormal_melanocyte_morpholog0.62629197
113MP0010329_abnormal_lipoprotein_level0.62561078
114MP0001177_atelectasis0.61327264
115MP0001346_abnormal_lacrimal_gland0.61195821
116MP0005171_absent_coat_pigmentation0.59876973
117MP0003631_nervous_system_phenotype0.58969471
118MP0002938_white_spotting0.58832601
119MP0005187_abnormal_penis_morphology0.58681078
120MP0000026_abnormal_inner_ear0.57624239
121MP0003172_abnormal_lysosome_physiology0.56564346
122MP0005535_abnormal_body_temperature0.56480540
123MP0000470_abnormal_stomach_morphology0.56175056
124MP0001188_hyperpigmentation0.55728392
125MP0004142_abnormal_muscle_tone0.54875224
126MP0003953_abnormal_hormone_level0.53896470
127MP0002152_abnormal_brain_morphology0.53854935
128MP0004233_abnormal_muscle_weight0.53735003
129MP0003183_abnormal_peptide_metabolism0.49428923
130MP0004510_myositis0.49207189

Predicted human phenotypes

RankGene SetZ-score
1Unilateral renal agenesis (HP:0000122)8.72759169
2Parakeratosis (HP:0001036)8.51954781
3Alopecia of scalp (HP:0002293)7.20417571
4Abnormality of dental color (HP:0011073)6.54067585
5Follicular hyperkeratosis (HP:0007502)6.48734475
6Bilateral sensorineural hearing impairment (HP:0008619)6.33497072
7Absent eyebrow (HP:0002223)6.22248688
8Absent eyelashes (HP:0000561)5.71901808
9Dynein arm defect of respiratory motile cilia (HP:0012255)5.46983997
10Absent/shortened dynein arms (HP:0200106)5.46983997
11Hyperphosphatemia (HP:0002905)5.10625183
12Focal motor seizures (HP:0011153)4.86028839
13Recurrent corneal erosions (HP:0000495)4.74021682
14Cheilitis (HP:0100825)4.42493399
15Chronic otitis media (HP:0000389)4.21683216
16Limb dystonia (HP:0002451)4.19933266
17Abnormality of calcium-phosphate metabolism (HP:0100530)4.17779805
18Tetany (HP:0001281)3.78935667
19Abolished electroretinogram (ERG) (HP:0000550)3.78659947
20Myokymia (HP:0002411)3.69680066
21Abnormal ciliary motility (HP:0012262)3.31909776
22Hemiparesis (HP:0001269)3.18968588
23Renal dysplasia (HP:0000110)3.18252262
24Hypothermia (HP:0002045)3.16228554
25Focal seizures (HP:0007359)3.15408998
26Abnormal respiratory motile cilium morphology (HP:0005938)3.04819740
27Abnormal respiratory epithelium morphology (HP:0012253)3.04819740
28Absent hair (HP:0002298)3.03397433
29Visual hallucinations (HP:0002367)2.93409109
30Erythroderma (HP:0001019)2.86264857
31Hypoglycemic coma (HP:0001325)2.74007117
32Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.73331165
33Hypoglycemic seizures (HP:0002173)2.72970631
34Gait imbalance (HP:0002141)2.72761284
35Torticollis (HP:0000473)2.70714360
36Broad-based gait (HP:0002136)2.70417711
37Ectropion (HP:0000656)2.69192188
38Febrile seizures (HP:0002373)2.67228795
39Polyphagia (HP:0002591)2.65680042
40Abnormal eating behavior (HP:0100738)2.64949088
41Amblyopia (HP:0000646)2.64794161
42Epileptic encephalopathy (HP:0200134)2.64108719
43Intention tremor (HP:0002080)2.62623356
44Ankle clonus (HP:0011448)2.61259289
45Ketoacidosis (HP:0001993)2.60183539
46Chronic sinusitis (HP:0011109)2.55852978
47Medial flaring of the eyebrow (HP:0010747)2.53127519
48Vertebral arch anomaly (HP:0008438)2.51146578
49Abnormal respiratory motile cilium physiology (HP:0012261)2.49735063
50Rhinitis (HP:0012384)2.47719762
51Abnormality of aromatic amino acid family metabolism (HP:0004338)2.46312414
52Status epilepticus (HP:0002133)2.45190320
53Intestinal atresia (HP:0011100)2.44151560
54Pheochromocytoma (HP:0002666)2.43201332
55Hyperactive renin-angiotensin system (HP:0000841)2.41118814
56Double outlet right ventricle (HP:0001719)2.40536563
57Congenital malformation of the right heart (HP:0011723)2.40536563
58Focal dystonia (HP:0004373)2.37232930
59Abnormality of renin-angiotensin system (HP:0000847)2.36931220
60Drooling (HP:0002307)2.35047758
61Progressive cerebellar ataxia (HP:0002073)2.34985567
62Mitral stenosis (HP:0001718)2.34928460
63Osteomalacia (HP:0002749)2.34478081
64Chronic hepatic failure (HP:0100626)2.33115743
65Metabolic alkalosis (HP:0200114)2.32809495
66Postural tremor (HP:0002174)2.29828979
67Papilledema (HP:0001085)2.27798463
68Hyperglycemia (HP:0003074)2.26407824
69Symptomatic seizures (HP:0011145)2.24965324
70Atonic seizures (HP:0010819)2.24096787
71Congenital primary aphakia (HP:0007707)2.23493975
72Muscular hypotonia of the trunk (HP:0008936)2.23112896
73Absence seizures (HP:0002121)2.21911023
74Decreased circulating renin level (HP:0003351)2.21779791
75Postural instability (HP:0002172)2.21632920
76Generalized tonic-clonic seizures (HP:0002069)2.21179683
77Palmoplantar hyperkeratosis (HP:0000972)2.20897519
78Truncal ataxia (HP:0002078)2.20830047
79Hypocalcemia (HP:0002901)2.19193794
80Insulin-resistant diabetes mellitus (HP:0000831)2.18807343
81Genetic anticipation (HP:0003743)2.17865834
82Neuroendocrine neoplasm (HP:0100634)2.16517183
83Akinesia (HP:0002304)2.16501054
84Hyperventilation (HP:0002883)2.15819238
85Excessive salivation (HP:0003781)2.14182638
86Neoplasm of the lung (HP:0100526)2.13171793
87Spastic gait (HP:0002064)2.11698837
88Keratitis (HP:0000491)2.11261307
89Urinary bladder sphincter dysfunction (HP:0002839)2.10989692
90Enlarged penis (HP:0000040)2.09727385
91Dysdiadochokinesis (HP:0002075)2.08894212
92Palmar hyperkeratosis (HP:0010765)2.07475074
93Fetal akinesia sequence (HP:0001989)2.07175508
94Generalized myoclonic seizures (HP:0002123)2.07131651
95Action tremor (HP:0002345)2.06406711
96Poor suck (HP:0002033)2.05068992
97Nephrogenic diabetes insipidus (HP:0009806)2.04439212
98Plagiocephaly (HP:0001357)2.04373304
99Dialeptic seizures (HP:0011146)2.03747587
100Impaired smooth pursuit (HP:0007772)2.02990484
101Prolonged QT interval (HP:0001657)2.01751270
102Bradykinesia (HP:0002067)2.01528563
103Craniofacial dystonia (HP:0012179)2.00418439
104Blepharitis (HP:0000498)2.00279522
105Hyperthyroidism (HP:0000836)1.99661418
106Hyperaldosteronism (HP:0000859)1.97467200
107Sleep apnea (HP:0010535)1.96337685
108Poor eye contact (HP:0000817)1.92017958
109Aqueductal stenosis (HP:0002410)1.91755583
110Small epiphyses (HP:0010585)1.90833304
111Impaired vibratory sensation (HP:0002495)1.90275621
112Mutism (HP:0002300)1.89120807
113Dysmetria (HP:0001310)1.88499816
114Genital tract atresia (HP:0001827)1.87925799
115Widely spaced teeth (HP:0000687)1.87696064
116Abnormality of binocular vision (HP:0011514)1.87140432
117Diplopia (HP:0000651)1.87140432
118Retinal atrophy (HP:0001105)1.86426127
119Diminished movement (HP:0002374)1.85754411
120Specific learning disability (HP:0001328)1.84587971
121Failure to thrive in infancy (HP:0001531)1.83896768
122Vaginal atresia (HP:0000148)1.82950288
123Erythema (HP:0010783)1.81645030
124Vertigo (HP:0002321)1.81556511
125Absent speech (HP:0001344)1.81536475
126Congenital sensorineural hearing impairment (HP:0008527)1.81020718
127Hyperinsulinemic hypoglycemia (HP:0000825)1.80287769
128Choreoathetosis (HP:0001266)1.79624550
129Amelogenesis imperfecta (HP:0000705)1.78290297
130Methylmalonic acidemia (HP:0002912)1.77742561
131Abnormality of vitamin B metabolism (HP:0004340)1.75239006
132Renal agenesis (HP:0000104)1.74946066
133Type II lissencephaly (HP:0007260)1.74636359
134Abnormality of the corticospinal tract (HP:0002492)1.74579483
135Hepatoblastoma (HP:0002884)1.74564973
136Abnormal EKG (HP:0003115)1.73911956
137Spastic tetraplegia (HP:0002510)1.73062664
138Abnormality of ocular smooth pursuit (HP:0000617)1.72720397
139Large for gestational age (HP:0001520)1.72057941
140Epileptiform EEG discharges (HP:0011182)1.71855644
141Neoplasm of the respiratory system (HP:0100606)1.71478825
142Corneal erosion (HP:0200020)1.71340226
143Conjugated hyperbilirubinemia (HP:0002908)1.71081642
144Syncope (HP:0001279)1.70542030
145EEG with generalized epileptiform discharges (HP:0011198)1.69444460
146Impaired social interactions (HP:0000735)1.65700856
147Abnormal social behavior (HP:0012433)1.65700856
148Hypokalemia (HP:0002900)1.65665794
149Abnormality of potassium homeostasis (HP:0011042)1.63501867
150Abnormal drinking behavior (HP:0030082)1.62785250
151Polydipsia (HP:0001959)1.62785250
152Anxiety (HP:0000739)1.62052608
153Increased circulating renin level (HP:0000848)1.60487794
154Spinal canal stenosis (HP:0003416)1.60392354
155Agitation (HP:0000713)1.59310888
156Arthropathy (HP:0003040)1.58973332
157Hypsarrhythmia (HP:0002521)1.58808605
158Gaze-evoked nystagmus (HP:0000640)1.58324268
159Supranuclear gaze palsy (HP:0000605)1.58057428
160Hypohidrosis (HP:0000966)1.58036308
161Cutaneous finger syndactyly (HP:0010554)1.55147601
162Ulnar claw (HP:0001178)1.54041082
163Abnormal biliary tract physiology (HP:0012439)1.53921785
164Bile duct proliferation (HP:0001408)1.53921785
165Depression (HP:0000716)1.53193375
166Impaired vibration sensation in the lower limbs (HP:0002166)1.52946605

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SIK37.61816803
2SIK25.72192676
3SIK14.54958374
4NTRK33.66196771
5EPHA43.45045108
6MARK32.36208597
7FGFR22.31345273
8MAP3K122.15259417
9PRKD32.03270059
10INSRR1.90255584
11EPHA21.81347049
12MAP3K91.77091947
13MAP3K41.72309398
14MARK21.72023518
15PRPF4B1.69870468
16TNIK1.66019717
17MAP2K71.65588463
18STK381.52969430
19DAPK21.50768701
20MARK11.50521971
21MAP2K41.45664221
22LATS11.45655658
23RIPK41.35450574
24MAPK131.33754719
25NTRK11.31996922
26LATS21.26155602
27PAK41.23381801
28CAMK11.22405588
29MAP3K21.22317622
30MAP4K21.21642301
31MINK11.19713452
32NTRK21.16959453
33WNK11.10606907
34CSNK1G11.09511489
35SGK21.06307718
36PAK61.05395630
37OXSR11.04754040
38AKT31.01529429
39MAP2K60.98179369
40CASK0.94396847
41CAMKK10.93359781
42CDK50.92390175
43SGK4940.90396719
44SGK2230.90396719
45ADRBK20.89407985
46GRK50.88843703
47CDK80.88696469
48MAP3K10.85492475
49GRK10.85107071
50MAP3K130.79649855
51SGK30.79328439
52PRKCH0.75810942
53UHMK10.74895376
54TAOK30.74083300
55TAOK10.72549013
56STK38L0.71424943
57PRKCG0.70624054
58ALK0.69187863
59BMPR20.68491071
60FES0.68037030
61TRPM70.67269041
62CAMK40.67174915
63DAPK10.67120295
64CAMK2A0.65677874
65PRKCZ0.65637092
66ERBB30.63844192
67HIPK20.63762014
68SGK10.63123700
69KSR20.62000792
70CSNK1G20.61255846
71EPHA30.61152321
72CDK190.57742230
73STK390.55222335
74CAMKK20.55176090
75TNK20.53597031
76WNK40.53532573
77FGFR30.53238503
78CSNK1D0.52321879
79DYRK20.52118856
80CAMK2G0.50147120
81TRIM280.49965430
82LIMK10.49589740
83TESK10.48746276
84STK110.48023381
85PTK2B0.47305219
86PLK20.45953572
87BMPR1B0.45870105
88ACVR1B0.45704257
89CAMK1D0.45084758
90PRKCE0.43985078
91CSNK1A1L0.43159102
92PRKAA10.42920793
93CDK30.42468410
94CDC42BPA0.42273435
95RET0.41997623
96CDK180.41644629
97CDK150.41326186
98CDK140.41274200
99CSNK1E0.41183113
100PRKG10.40985677
101WNK30.40960502
102IRAK20.40399262
103ARAF0.39940578
104KSR10.39694987
105DYRK1A0.36857400
106PNCK0.36442914
107PAK30.35737347
108CSNK1G30.34853350
109PRKACB0.34086561
110CAMK2B0.33543709
111CDK11A0.32792206
112FER0.32040115
113RPS6KA30.30862995
114FYN0.28728086
115PKN10.27887277
116PASK0.27344637
117CAMK1G0.26967223
118MAP3K70.26764902
119CSNK1A10.26589649
120FGR0.26485497
121PRKD20.26073282
122MAPK100.25022361
123MAPK150.24973302
124FRK0.24313070
125NEK60.23597135
126PRKCA0.23220931
127PDK10.22647389
128CAMK2D0.21893856
129PRKACA0.21870039
130PHKG10.20626763
131PHKG20.20626763
132PINK10.20614037
133ADRBK10.20485315

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.50026152
2Synaptic vesicle cycle_Homo sapiens_hsa047212.88960831
3Insulin secretion_Homo sapiens_hsa049112.65658395
4GABAergic synapse_Homo sapiens_hsa047272.53478223
5Circadian entrainment_Homo sapiens_hsa047132.52284402
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.51837429
7Morphine addiction_Homo sapiens_hsa050322.47240268
8Glutamatergic synapse_Homo sapiens_hsa047242.35323043
9Maturity onset diabetes of the young_Homo sapiens_hsa049502.18777419
10Type II diabetes mellitus_Homo sapiens_hsa049302.17926335
11Amphetamine addiction_Homo sapiens_hsa050312.12516536
12Long-term potentiation_Homo sapiens_hsa047202.11346990
13Taste transduction_Homo sapiens_hsa047422.06995508
14Olfactory transduction_Homo sapiens_hsa047402.02112476
15Serotonergic synapse_Homo sapiens_hsa047261.99333927
16Calcium signaling pathway_Homo sapiens_hsa040201.92225482
17Cholinergic synapse_Homo sapiens_hsa047251.89278145
18Dopaminergic synapse_Homo sapiens_hsa047281.82866989
19Cocaine addiction_Homo sapiens_hsa050301.80725704
20Salivary secretion_Homo sapiens_hsa049701.79458688
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.78902928
22Gastric acid secretion_Homo sapiens_hsa049711.68716896
23Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.67050557
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.61505162
25Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.59049659
26Butanoate metabolism_Homo sapiens_hsa006501.58159135
27Renin secretion_Homo sapiens_hsa049241.56666982
28Vitamin B6 metabolism_Homo sapiens_hsa007501.53400477
29Long-term depression_Homo sapiens_hsa047301.49072519
30Mineral absorption_Homo sapiens_hsa049781.43376444
31Axon guidance_Homo sapiens_hsa043601.41998358
32Phosphatidylinositol signaling system_Homo sapiens_hsa040701.38811637
33Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.31122829
34Oxytocin signaling pathway_Homo sapiens_hsa049211.30104407
35Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.23804177
36cAMP signaling pathway_Homo sapiens_hsa040241.20549159
37Type I diabetes mellitus_Homo sapiens_hsa049401.18027594
38Pancreatic secretion_Homo sapiens_hsa049721.14236125
39SNARE interactions in vesicular transport_Homo sapiens_hsa041301.13409171
40Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.12470642
41GnRH signaling pathway_Homo sapiens_hsa049121.11321897
42Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.10693712
43Carbohydrate digestion and absorption_Homo sapiens_hsa049731.09718992
44ErbB signaling pathway_Homo sapiens_hsa040121.07864701
45Folate biosynthesis_Homo sapiens_hsa007901.07712614
46Gap junction_Homo sapiens_hsa045400.97954251
47Estrogen signaling pathway_Homo sapiens_hsa049150.97681497
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.97380809
49Ovarian steroidogenesis_Homo sapiens_hsa049130.96168819
50cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95546815
51Circadian rhythm_Homo sapiens_hsa047100.94482500
52Oxidative phosphorylation_Homo sapiens_hsa001900.90265923
53Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.89691243
54Vascular smooth muscle contraction_Homo sapiens_hsa042700.88016209
55Renal cell carcinoma_Homo sapiens_hsa052110.84638555
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.84246135
57Glioma_Homo sapiens_hsa052140.84026996
58Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.82886355
59Protein export_Homo sapiens_hsa030600.82810861
60Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.80784111
61Ras signaling pathway_Homo sapiens_hsa040140.80190599
62African trypanosomiasis_Homo sapiens_hsa051430.75819974
63Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75431549
64Oocyte meiosis_Homo sapiens_hsa041140.75008725
65Thyroid hormone synthesis_Homo sapiens_hsa049180.73604359
66Ether lipid metabolism_Homo sapiens_hsa005650.73456132
67Melanogenesis_Homo sapiens_hsa049160.72948027
68Regulation of autophagy_Homo sapiens_hsa041400.71641073
69Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.71240697
70MAPK signaling pathway_Homo sapiens_hsa040100.70520699
71Collecting duct acid secretion_Homo sapiens_hsa049660.68469559
72Dilated cardiomyopathy_Homo sapiens_hsa054140.67783122
73Sulfur metabolism_Homo sapiens_hsa009200.66968611
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.66398865
75Dorso-ventral axis formation_Homo sapiens_hsa043200.66320077
76Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64517192
77Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.63867485
78Bile secretion_Homo sapiens_hsa049760.63602568
79Choline metabolism in cancer_Homo sapiens_hsa052310.63359310
80Alzheimers disease_Homo sapiens_hsa050100.63189060
81Wnt signaling pathway_Homo sapiens_hsa043100.63171021
82Glucagon signaling pathway_Homo sapiens_hsa049220.62864713
83Toll-like receptor signaling pathway_Homo sapiens_hsa046200.61212291
84Rap1 signaling pathway_Homo sapiens_hsa040150.60811553
85Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60573333
86Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58602378
87Melanoma_Homo sapiens_hsa052180.57998140
88Vibrio cholerae infection_Homo sapiens_hsa051100.55407645
89Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.55209782
90ABC transporters_Homo sapiens_hsa020100.54625995
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54590538
92Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.53539870
93Sphingolipid metabolism_Homo sapiens_hsa006000.52446534
94Tryptophan metabolism_Homo sapiens_hsa003800.51528273
95Parkinsons disease_Homo sapiens_hsa050120.50308899
96beta-Alanine metabolism_Homo sapiens_hsa004100.44579445
97Prolactin signaling pathway_Homo sapiens_hsa049170.42789583
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.42171065
99Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42015787
100Inositol phosphate metabolism_Homo sapiens_hsa005620.41062835
101Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40492402
102Peroxisome_Homo sapiens_hsa041460.39741470
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.37165113
104Regulation of actin cytoskeleton_Homo sapiens_hsa048100.37161817
105Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.35607257
106Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33571777
107Phototransduction_Homo sapiens_hsa047440.33476655
108mTOR signaling pathway_Homo sapiens_hsa041500.33021255
109Tuberculosis_Homo sapiens_hsa051520.32794950
110Cardiac muscle contraction_Homo sapiens_hsa042600.31667516
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.31522645
112Arginine biosynthesis_Homo sapiens_hsa002200.30909524
113T cell receptor signaling pathway_Homo sapiens_hsa046600.30707880
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.29354421
115Fatty acid biosynthesis_Homo sapiens_hsa000610.27423845
116VEGF signaling pathway_Homo sapiens_hsa043700.27408109
117Thyroid hormone signaling pathway_Homo sapiens_hsa049190.27317797
118Prion diseases_Homo sapiens_hsa050200.26955220
119Alcoholism_Homo sapiens_hsa050340.26896254
120Fatty acid elongation_Homo sapiens_hsa000620.26696005
121Non-small cell lung cancer_Homo sapiens_hsa052230.26611581
122Chemokine signaling pathway_Homo sapiens_hsa040620.24162218
123Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.24097504
124Fatty acid metabolism_Homo sapiens_hsa012120.23533427
125Histidine metabolism_Homo sapiens_hsa003400.22901784

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