RIMBP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.83325928
2plasma membrane fusion (GO:0045026)9.77106897
3motile cilium assembly (GO:0044458)9.66693277
4spermatid development (GO:0007286)9.52100446
5piRNA metabolic process (GO:0034587)9.06173621
6regulation of cilium movement (GO:0003352)8.92895256
7reproduction (GO:0000003)8.71542743
8cilium movement (GO:0003341)8.27370835
9epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)8.04685445
10male meiosis (GO:0007140)7.92624651
11synaptonemal complex organization (GO:0070193)7.75627189
12synaptonemal complex assembly (GO:0007130)7.42605232
13single fertilization (GO:0007338)7.20948747
14sperm capacitation (GO:0048240)6.92448782
15negative regulation of inclusion body assembly (GO:0090084)6.66701726
16spermatogenesis (GO:0007283)6.42196590
17male gamete generation (GO:0048232)6.39895449
18fertilization (GO:0009566)6.28034177
19organic cation transport (GO:0015695)6.01908503
20microtubule depolymerization (GO:0007019)5.95705174
21gamete generation (GO:0007276)5.88109711
22DNA methylation involved in gamete generation (GO:0043046)5.70185467
23male meiosis I (GO:0007141)5.69015206
24establishment of protein localization to Golgi (GO:0072600)5.56476879
25regulation of inclusion body assembly (GO:0090083)5.53432654
26protein targeting to Golgi (GO:0000042)5.52767560
27ventricular system development (GO:0021591)5.50245007
28germ cell development (GO:0007281)5.43878425
29cellular process involved in reproduction in multicellular organism (GO:0022412)5.42880504
30retrograde transport, vesicle recycling within Golgi (GO:0000301)5.35608093
31regulation of microtubule-based movement (GO:0060632)5.28253562
32calcium ion-dependent exocytosis (GO:0017156)5.16437480
33chromosome organization involved in meiosis (GO:0070192)5.12156916
34phosphatidylethanolamine biosynthetic process (GO:0006646)5.08751509
35seminiferous tubule development (GO:0072520)5.06677309
36antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.97182881
37microtubule severing (GO:0051013)4.90895827
38cell recognition (GO:0008037)4.85244095
39meiotic nuclear division (GO:0007126)4.79437441
40left/right pattern formation (GO:0060972)4.76418921
41meiosis I (GO:0007127)4.63053833
42multicellular organismal reproductive process (GO:0048609)4.62755022
43phosphatidylethanolamine metabolic process (GO:0046337)4.59598617
44rRNA methylation (GO:0031167)4.36304862
45nuclear pore organization (GO:0006999)4.33796547
46chromatin silencing (GO:0006342)4.25067795
47chromosome condensation (GO:0030261)4.24083551
48regulation of Rab GTPase activity (GO:0032313)4.21243941
49positive regulation of Rab GTPase activity (GO:0032851)4.21243941
50pore complex assembly (GO:0046931)4.17573557
51histone H3-K36 demethylation (GO:0070544)4.15681004
52meiotic cell cycle (GO:0051321)4.15662515
53DNA packaging (GO:0006323)4.15035844
54protein localization to cilium (GO:0061512)4.05058136
55glycerol ether metabolic process (GO:0006662)3.90995139
56protein polyglutamylation (GO:0018095)3.90509577
57chaperone-mediated protein complex assembly (GO:0051131)3.83177710
58genitalia morphogenesis (GO:0035112)3.81369018
59monoubiquitinated protein deubiquitination (GO:0035520)3.78528362
60spermatid nucleus differentiation (GO:0007289)3.76678219
61multicellular organismal development (GO:0007275)3.72524128
62peptidyl-threonine dephosphorylation (GO:0035970)3.66031052
63protein localization to Golgi apparatus (GO:0034067)3.60694419
64ether metabolic process (GO:0018904)3.60669124
65histone H3-K9 demethylation (GO:0033169)3.58042951
66negative regulation of gene expression, epigenetic (GO:0045814)3.57046704
67positive regulation of gamma-delta T cell activation (GO:0046645)3.49262045
68regulation of spindle checkpoint (GO:0090231)3.48803927
69peptidyl-lysine dimethylation (GO:0018027)3.48035387
70gene silencing by RNA (GO:0031047)3.46055535
71carnitine transport (GO:0015879)3.43262911
72amino-acid betaine transport (GO:0015838)3.43262911
73histone lysine demethylation (GO:0070076)3.41339211
74regulation of gamma-delta T cell differentiation (GO:0045586)3.38954097
75rRNA modification (GO:0000154)3.38813405
76regulation of histone H3-K27 methylation (GO:0061085)3.38269849
77DNA conformation change (GO:0071103)3.36477274
78negative regulation of granulocyte differentiation (GO:0030853)3.36349076
79carnitine transmembrane transport (GO:1902603)3.35236925
80histone demethylation (GO:0016577)3.32789057
81response to pheromone (GO:0019236)3.31084385
82mature B cell differentiation involved in immune response (GO:0002313)3.29510584
83negative regulation of organelle assembly (GO:1902116)3.27496189
84intraciliary transport (GO:0042073)3.25411779
85protein refolding (GO:0042026)3.24214124
86B cell receptor signaling pathway (GO:0050853)3.22952299
87mitotic sister chromatid cohesion (GO:0007064)3.20562373
88axoneme assembly (GO:0035082)3.19434005
89regulation of ARF GTPase activity (GO:0032312)3.17281673
90meiotic cell cycle process (GO:1903046)3.15964652
91definitive hemopoiesis (GO:0060216)3.14048238
92regulation of granulocyte differentiation (GO:0030852)3.11240344
93microtubule-based movement (GO:0007018)3.11081334
94sequestering of actin monomers (GO:0042989)3.09639350
95positive T cell selection (GO:0043368)3.07969682
96regulation of T-helper 2 cell differentiation (GO:0045628)3.07122318
97RNA localization (GO:0006403)3.05074236
98centriole assembly (GO:0098534)3.04247965
99interferon-gamma secretion (GO:0072643)3.03204072
100synapsis (GO:0007129)3.02674829
101histone mRNA catabolic process (GO:0071044)3.02570260
102microtubule polymerization or depolymerization (GO:0031109)3.02022500
103mitotic G1 DNA damage checkpoint (GO:0031571)3.00217434
104polyol catabolic process (GO:0046174)3.00154610
105nucleus organization (GO:0006997)3.00132301
106cilium organization (GO:0044782)2.99899593
107protein K48-linked deubiquitination (GO:0071108)2.98408147
108microtubule nucleation (GO:0007020)2.98384243
109positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.96507004
110regulation of gamma-delta T cell activation (GO:0046643)2.95185970
111insulin-like growth factor receptor signaling pathway (GO:0048009)2.94993817
112positive thymic T cell selection (GO:0045059)2.94897031
113protein dealkylation (GO:0008214)2.94787301
114protein demethylation (GO:0006482)2.94787301
115homeostasis of number of cells within a tissue (GO:0048873)2.94623150
116single strand break repair (GO:0000012)2.94147827
117positive regulation of granulocyte differentiation (GO:0030854)2.93578867
118cellular response to ethanol (GO:0071361)2.92603699
119negative regulation of histone methylation (GO:0031061)2.92241860
120alditol metabolic process (GO:0019400)2.91585516
121nuclear pore complex assembly (GO:0051292)2.89879781
122cilium morphogenesis (GO:0060271)2.89364584
123regulation of B cell receptor signaling pathway (GO:0050855)2.87027393
124centriole replication (GO:0007099)2.86484068
125cilium assembly (GO:0042384)2.85404692
126mature B cell differentiation (GO:0002335)2.84806393
127nucleoside diphosphate phosphorylation (GO:0006165)2.84285104
128peptidyl-glutamic acid modification (GO:0018200)2.81837468
129glycolytic process (GO:0006096)2.80767976
130G1 DNA damage checkpoint (GO:0044783)2.80243339
131regulation of centriole replication (GO:0046599)2.78188681
132protein K11-linked deubiquitination (GO:0035871)2.77895540
133lactate metabolic process (GO:0006089)2.77742894
134cellular component assembly involved in morphogenesis (GO:0010927)2.75923273
135RNA destabilization (GO:0050779)2.75792753
136gene silencing (GO:0016458)2.71471317
137phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.70390397
138hepatocyte apoptotic process (GO:0097284)2.69743498
139mitotic G1/S transition checkpoint (GO:0044819)2.69012512
140coronary vasculature morphogenesis (GO:0060977)2.66612892
141regulation of meiosis I (GO:0060631)2.65711299
142polyamine biosynthetic process (GO:0006596)2.63517104
143Golgi to endosome transport (GO:0006895)2.63091598
144regulation of cilium assembly (GO:1902017)2.58377955
145sexual reproduction (GO:0019953)2.56946897
146protein-DNA complex disassembly (GO:0032986)2.48804260
147nucleosome disassembly (GO:0006337)2.48804260
148sperm motility (GO:0030317)12.9918784
149fusion of sperm to egg plasma membrane (GO:0007342)12.8446295
150cilium or flagellum-dependent cell motility (GO:0001539)11.8606631
151acrosome reaction (GO:0007340)11.6006106
152sperm-egg recognition (GO:0035036)11.2305752
153acrosome assembly (GO:0001675)10.7752822
154axonemal dynein complex assembly (GO:0070286)10.5878515
155cell wall macromolecule catabolic process (GO:0016998)10.5332957
156cell wall macromolecule metabolic process (GO:0044036)10.5332957
157multicellular organism reproduction (GO:0032504)10.4714155
158binding of sperm to zona pellucida (GO:0007339)10.3628730
159cell-cell recognition (GO:0009988)10.0383260

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.05543503
2TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.23413834
3BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse3.38058842
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.94035868
5SCL_19346495_ChIP-Seq_HPC-7_Human2.71046637
6PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.68801488
7STAT6_21828071_ChIP-Seq_BEAS2B_Human2.60452837
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.51955898
9VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.50691302
10CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.43434056
11MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.41020712
12RUNX_20019798_ChIP-Seq_JUKART_Human2.26858522
13E2F7_22180533_ChIP-Seq_HELA_Human2.25031977
14GATA1_26923725_Chip-Seq_HPCs_Mouse2.20203450
15IRF8_22096565_ChIP-ChIP_GC-B_Human2.11891803
16VDR_22108803_ChIP-Seq_LS180_Human2.08527693
17VDR_21846776_ChIP-Seq_THP-1_Human2.05897913
18CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.05557275
19ZNF274_21170338_ChIP-Seq_K562_Hela2.05503429
20MYC_22102868_ChIP-Seq_BL_Human2.01153273
21MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse10.9584824
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse10.1688585
23EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.99719006
24SPI1_23127762_ChIP-Seq_K562_Human1.90213539
25BP1_19119308_ChIP-ChIP_Hs578T_Human1.89893115
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.89515247
27ELK4_26923725_Chip-Seq_MESODERM_Mouse1.87395820
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.86992267
29FLI1_27457419_Chip-Seq_LIVER_Mouse1.86028438
30* TCF7_22412390_ChIP-Seq_EML_Mouse1.82612621
31SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.77892825
32KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.77683213
33MYB_26560356_Chip-Seq_TH2_Human1.76658654
34MYB_26560356_Chip-Seq_TH1_Human1.75823221
35PKCTHETA_26484144_Chip-Seq_BREAST_Human1.75520452
36KDM2B_26808549_Chip-Seq_SUP-B15_Human1.72610319
37GATA1_19941826_ChIP-Seq_K562_Human1.71232645
38STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.66583300
39E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.66137686
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.65104130
41LXR_22292898_ChIP-Seq_THP-1_Human1.64793393
42* FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.64675738
43* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.63865430
44STAT1_17558387_ChIP-Seq_HELA_Human1.63431212
45SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.61154877
46MAF_26560356_Chip-Seq_TH1_Human1.60248523
47TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.60190197
48UTX_26944678_Chip-Seq_JUKART_Human1.59769175
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.58808946
50KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.58498582
51KDM2B_26808549_Chip-Seq_DND41_Human1.56693436
52SMC4_20622854_ChIP-Seq_HELA_Human1.54868260
53GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.54135076
54BCOR_27268052_Chip-Seq_Bcells_Human1.53260307
55TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.52014659
56VDR_24763502_ChIP-Seq_THP-1_Human1.50792447
57GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48864759
58* MAF_26560356_Chip-Seq_TH2_Human1.48402967
59SOX2_22085726_ChIP-Seq_NPCs_Mouse1.48350081
60FOXM1_23109430_ChIP-Seq_U2OS_Human1.47947415
61MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.47167293
62GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.46606582
63P68_20966046_ChIP-Seq_HELA_Human1.46106397
64CBP_20019798_ChIP-Seq_JUKART_Human1.42651994
65IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.42651994
66GATA3_21867929_ChIP-Seq_CD8_Mouse1.41488422
67* WDR5_24793694_ChIP-Seq_LNCAP_Human1.40295920
68BCL6_27268052_Chip-Seq_Bcells_Human1.40112870
69GATA3_27048872_Chip-Seq_THYMUS_Human1.36800088
70RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.33610801
71NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.33451541
72RAC3_21632823_ChIP-Seq_H3396_Human1.32640791
73REST_21632747_ChIP-Seq_MESCs_Mouse1.30946999
74KAP1_22055183_ChIP-Seq_ESCs_Mouse1.30900217
75* FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.30701376
76RUNX1_27514584_Chip-Seq_MCF-7_Human1.30036676
77GATA1_19941827_ChIP-Seq_MEL_Mouse1.29184960
78GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28746500
79KDM2B_26808549_Chip-Seq_REH_Human1.27237889
80MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.27231935
81PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.26511786
82* P300_27268052_Chip-Seq_Bcells_Human1.26422530
83LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.25883200
84P53_21459846_ChIP-Seq_SAOS-2_Human1.25594809
85* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.25534492
86* TAL1_26923725_Chip-Seq_HPCs_Mouse1.24513293
87ARNT_22903824_ChIP-Seq_MCF-7_Human1.22682781
88PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.22325233
89NFE2_27457419_Chip-Seq_LIVER_Mouse1.21624250
90EGR1_19374776_ChIP-ChIP_THP-1_Human1.21415041
91CIITA_25753668_ChIP-Seq_RAJI_Human1.20729685
92FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.18612009
93TP63_22573176_ChIP-Seq_HFKS_Human1.18160694
94* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.17211292
95PCGF2_27294783_Chip-Seq_NPCs_Mouse1.16467506
96RUNX1_26923725_Chip-Seq_HPCs_Mouse1.15749344
97DROSHA_22980978_ChIP-Seq_HELA_Human1.14451019
98* SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.14100375
99FLI1_21867929_ChIP-Seq_TH2_Mouse1.13691935
100PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.11996837
101KDM2B_26808549_Chip-Seq_JURKAT_Human1.11738256
102TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09786251
103POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.09786251
104RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.09651482
105GATA2_19941826_ChIP-Seq_K562_Human1.09374610
106RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08789228
107CBX2_27304074_Chip-Seq_ESCs_Mouse1.07871951
108RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07615422
109* GATA3_21867929_ChIP-Seq_TH1_Mouse1.06811877
110TP53_22127205_ChIP-Seq_IMR90_Human1.06741845
111TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06632055
112* RAD21_21589869_ChIP-Seq_MESCs_Mouse1.06537384
113CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.06151119
114AR_21572438_ChIP-Seq_LNCaP_Human1.05566366
115ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.05068421
116PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.05040800
117SUZ12_27294783_Chip-Seq_NPCs_Mouse1.04982059
118ERA_21632823_ChIP-Seq_H3396_Human1.04885924
119NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.04135391
120TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03905202
121VDR_24787735_ChIP-Seq_THP-1_Human1.03574696
122E2F1_20622854_ChIP-Seq_HELA_Human1.03524486
123SPI1_20517297_ChIP-Seq_HL60_Human1.02211971
124SA1_27219007_Chip-Seq_ERYTHROID_Human1.02040355
125YY1_22570637_ChIP-Seq_MALME-3M_Human1.01969324
126EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.01813602
127* GF1_26923725_Chip-Seq_HPCs_Mouse1.01734343
128ERG_20517297_ChIP-Seq_VCAP_Human1.01697116
129SPI1_26923725_Chip-Seq_HPCs_Mouse1.01602659
130EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.00732263
131MYC_27129775_Chip-Seq_CORNEA_Mouse1.00696220
132CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00515661
133IRF8_21731497_ChIP-ChIP_J774_Mouse1.00353033
134PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.99832656
135* SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99233914
136IRF8_27001747_Chip-Seq_BMDM_Mouse0.98834237
137STAT4_19710469_ChIP-ChIP_TH1__Mouse0.97996197
138CRX_20693478_ChIP-Seq_RETINA_Mouse0.97691195
139RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.97628506
140TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97601862
141EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.96692889
142OCT4_20526341_ChIP-Seq_ESCs_Human0.96110911
143* CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.95710210
144SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.95348463
145TDRD3_21172665_ChIP-Seq_MCF-7_Human0.95343654
146ELF1_20517297_ChIP-Seq_JURKAT_Human0.95151907
147CTCF_20526341_ChIP-Seq_ESCs_Human0.95078460
148ESET_19884257_ChIP-Seq_ESCs_Mouse0.94881303
149SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.93920788
150ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.93861832
151NCOR1_26117541_ChIP-Seq_K562_Human0.93640676
152CTCF_21964334_Chip-Seq_Bcells_Human0.93292930
153SPI1_23547873_ChIP-Seq_NB4_Human0.92986389
154SOX2_21211035_ChIP-Seq_LN229_Human0.92968270
155* RXRA_24833708_ChIP-Seq_LIVER_Mouse0.92665806
156* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.91870606
157CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.91605402
158TET1_21451524_ChIP-Seq_MESCs_Mouse0.91590369
159* RARA_24833708_ChIP-Seq_LIVER_Mouse0.90522850
160NANOG_18555785_Chip-Seq_ESCs_Mouse0.89832034
161MYB_21317192_ChIP-Seq_ERMYB_Mouse0.89700196
162CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.89524731
163* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.89012401
164LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.88843010
165GATA1_19941827_ChIP-Seq_MEL86_Mouse0.88710209
166SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88110034
167SOX11_22085726_ChIP-Seq_ESNs_Mouse0.87881400
168AHR_22903824_ChIP-Seq_MCF-7_Human0.87712857
169CTCF_27219007_Chip-Seq_ERYTHROID_Human0.87217091
170FLI1_21867929_ChIP-Seq_CD8_Mouse0.87052688
171OCT4_18555785_Chip-Seq_ESCs_Mouse0.86224589
172TP63_19390658_ChIP-ChIP_HaCaT_Human0.85860127
173RNF2_27304074_Chip-Seq_NSC_Mouse0.85727670
174OCT4_21477851_ChIP-Seq_ESCs_Mouse0.85121477
175NFYB_21822215_ChIP-Seq_K562_Human0.84792030
176PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.84428156
177* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83173584
178PHF8_20622854_ChIP-Seq_HELA_Human0.82957351
179TBL1_22424771_ChIP-Seq_293T_Human0.82718803
180DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.82482556
181UBF1/2_26484160_Chip-Seq_HMECs_Human0.82273486
182SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.82087827
183P53_22387025_ChIP-Seq_ESCs_Mouse0.81849777
184JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.81401442
185MYC_19829295_ChIP-Seq_ESCs_Human0.81004285
186STAT3_18555785_ChIP-Seq_MESCs_Mouse0.80696397

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0003698_abnormal_male_reproductive6.03582104
2* MP0001929_abnormal_gametogenesis5.49324166
3MP0008877_abnormal_DNA_methylation4.64434647
4MP0002210_abnormal_sex_determination3.64483567
5* MP0002161_abnormal_fertility/fecundity3.29029557
6MP0001145_abnormal_male_reproductive3.10144957
7MP0005451_abnormal_body_composition3.04963781
8MP0002653_abnormal_ependyma_morphology2.98267494
9MP0005310_abnormal_salivary_gland2.72841508
10MP0000653_abnormal_sex_gland2.68101950
11MP0003763_abnormal_thymus_physiology2.53543990
12MP0001348_abnormal_lacrimal_gland2.51162394
13MP0005670_abnormal_white_adipose2.49982177
14MP0001835_abnormal_antigen_presentation2.19766844
15MP0002160_abnormal_reproductive_system2.05223283
16* MP0005410_abnormal_fertilization15.7296718
17MP0003646_muscle_fatigue1.86916599
18MP0002132_abnormal_respiratory_system1.81822172
19MP0002396_abnormal_hematopoietic_system1.76871193
20MP0003303_peritoneal_inflammation1.75775194
21MP0005623_abnormal_meninges_morphology1.75611304
22MP0009697_abnormal_copulation1.63275118
23MP0002009_preneoplasia1.62775619
24MP0003091_abnormal_cell_migration1.57563270
25MP0000703_abnormal_thymus_morphology1.55655322
26MP0002398_abnormal_bone_marrow1.51178752
27MP0001800_abnormal_humoral_immune1.48111115
28MP0004233_abnormal_muscle_weight1.43605339
29MP0000015_abnormal_ear_pigmentation1.42072983
30MP0002282_abnormal_trachea_morphology1.41290838
31MP0002166_altered_tumor_susceptibility1.39717633
32MP0004381_abnormal_hair_follicle1.37056428
33MP0005083_abnormal_biliary_tract1.36937483
34MP0002722_abnormal_immune_system1.36325996
35MP0004185_abnormal_adipocyte_glucose1.33641706
36MP0005464_abnormal_platelet_physiology1.30958763
37MP0003300_gastrointestinal_ulcer1.26079792
38MP0003436_decreased_susceptibility_to1.22632875
39MP0002723_abnormal_immune_serum1.21751078
40MP0002452_abnormal_antigen_presenting1.20357904
41MP0002420_abnormal_adaptive_immunity1.18682692
42MP0003705_abnormal_hypodermis_morpholog1.17439908
43MP0002419_abnormal_innate_immunity1.16692803
44MP0001819_abnormal_immune_cell1.16374135
45MP0005076_abnormal_cell_differentiation1.16364926
46MP0000716_abnormal_immune_system1.14297920
47MP0000685_abnormal_immune_system1.13942728
48MP0003172_abnormal_lysosome_physiology1.13740128
49MP0003828_pulmonary_edema1.11686230
50MP0000689_abnormal_spleen_morphology1.09610582
51MP0000681_abnormal_thyroid_gland1.07628320
52MP0004947_skin_inflammation1.07148596
53MP0001984_abnormal_olfaction1.03807608
54MP0005389_reproductive_system_phenotype1.03013233
55MP0000371_diluted_coat_color1.02184376
56MP0008260_abnormal_autophagy1.02120006
57MP0008058_abnormal_DNA_repair1.01406656
58MP0005025_abnormal_response_to1.00919489
59MP0000678_abnormal_parathyroid_gland0.99823034
60MP0002429_abnormal_blood_cell0.98360377
61MP0001765_abnormal_ion_homeostasis0.97939446
62MP0005000_abnormal_immune_tolerance0.97566391
63MP0000003_abnormal_adipose_tissue0.93495309
64MP0009046_muscle_twitch0.92881833
65MP0010094_abnormal_chromosome_stability0.91718103
66MP0002405_respiratory_system_inflammati0.90637372
67MP0005647_abnormal_sex_gland0.89664536
68MP0008995_early_reproductive_senescence0.89116280
69MP0003115_abnormal_respiratory_system0.88746527
70MP0008057_abnormal_DNA_replication0.87522655
71MP0010352_gastrointestinal_tract_polyps0.86615400
72MP0005377_hearing/vestibular/ear_phenot0.86567290
73MP0003878_abnormal_ear_physiology0.86567290
74MP0002019_abnormal_tumor_incidence0.85900206
75MP0002249_abnormal_larynx_morphology0.84065112
76MP0003011_delayed_dark_adaptation0.81799601
77MP0001873_stomach_inflammation0.81392918
78MP0000733_abnormal_muscle_development0.81091125
79MP0002006_tumorigenesis0.79815459
80MP0001790_abnormal_immune_system0.77596023
81MP0005387_immune_system_phenotype0.77596023
82MP0000569_abnormal_digit_pigmentation0.75233066
83MP0003656_abnormal_erythrocyte_physiolo0.73537105
84MP0005671_abnormal_response_to0.71455215
85MP0002998_abnormal_bone_remodeling0.70966716
86MP0000537_abnormal_urethra_morphology0.70188774
87MP0002138_abnormal_hepatobiliary_system0.69033444
88MP0002332_abnormal_exercise_endurance0.68604814
89MP0003111_abnormal_nucleus_morphology0.67781892
90MP0004130_abnormal_muscle_cell0.67161236
91MP0000358_abnormal_cell_content/0.66390088
92MP0003632_abnormal_nervous_system0.66106747
93MP0000465_gastrointestinal_hemorrhage0.65726052
94MP0003718_maternal_effect0.63995144
95MP0009278_abnormal_bone_marrow0.63296789
96MP0003866_abnormal_defecation0.63293793
97MP0001879_abnormal_lymphatic_vessel0.63057732
98MP0002234_abnormal_pharynx_morphology0.61665153
99MP0000350_abnormal_cell_proliferation0.61447607
100MP0000249_abnormal_blood_vessel0.60981546
101MP0008007_abnormal_cellular_replicative0.60944972
102MP0005621_abnormal_cell_physiology0.60741446
103MP0001545_abnormal_hematopoietic_system0.60147166
104MP0005397_hematopoietic_system_phenotyp0.60147166
105MP0000470_abnormal_stomach_morphology0.59973773
106MP0003329_amyloid_beta_deposits0.57908237
107MP0005666_abnormal_adipose_tissue0.57226585
108MP0003786_premature_aging0.52949138
109MP0001293_anophthalmia0.52192635
110MP0003699_abnormal_female_reproductive0.51929745
111MP0003950_abnormal_plasma_membrane0.50625593
112MP0001324_abnormal_eye_pigmentation0.48597358
113MP0005636_abnormal_mineral_homeostasis0.46862535
114MP0008961_abnormal_basal_metabolism0.46831933
115MP0001730_embryonic_growth_arrest0.45788266
116MP0000534_abnormal_ureter_morphology0.43286166
117MP0002928_abnormal_bile_duct0.43198076
118MP0004036_abnormal_muscle_relaxation0.42467091
119MP0002269_muscular_atrophy0.42332662
120MP0006036_abnormal_mitochondrial_physio0.39956120
121MP0004808_abnormal_hematopoietic_stem0.39159681
122MP0005253_abnormal_eye_physiology0.37352214
123MP0005551_abnormal_eye_electrophysiolog0.37113424
124MP0010307_abnormal_tumor_latency0.36809419
125MP0003861_abnormal_nervous_system0.36741955
126MP0005423_abnormal_somatic_nervous0.35980035
127MP0004811_abnormal_neuron_physiology0.34990799
128MP0003942_abnormal_urinary_system0.34574460
129MP0001661_extended_life_span0.34070388
130MP0005391_vision/eye_phenotype0.34045757
131MP0003879_abnormal_hair_cell0.33946958
132MP0001764_abnormal_homeostasis0.33828853
133MP0009115_abnormal_fat_cell0.33369529
134MP0001727_abnormal_embryo_implantation0.32009429
135MP0002152_abnormal_brain_morphology0.31548373
136MP0003077_abnormal_cell_cycle0.31483374
137MP0001119_abnormal_female_reproductive0.31236813
138MP0002971_abnormal_brown_adipose0.31188962
139MP0004133_heterotaxia0.28884064
140MP0006035_abnormal_mitochondrial_morpho0.28806705
141MP0002084_abnormal_developmental_patter0.28237475
142MP0000313_abnormal_cell_death0.28010720
143MP0001986_abnormal_taste_sensitivity0.27137920
144MP0000751_myopathy0.26054602
145MP0002102_abnormal_ear_morphology0.25418933
146MP0002092_abnormal_eye_morphology0.23680430
147MP0000604_amyloidosis0.23653818
148MP0003948_abnormal_gas_homeostasis0.22904944
149MP0001697_abnormal_embryo_size0.22677351
150MP0001672_abnormal_embryogenesis/_devel0.22355662
151MP0005380_embryogenesis_phenotype0.22355662
152MP0003633_abnormal_nervous_system0.22206528
153MP0002169_no_abnormal_phenotype0.21657781
154MP0002873_normal_phenotype0.21380823
155MP0001849_ear_inflammation0.21168995
156MP0002295_abnormal_pulmonary_circulatio0.20912656
157MP0003787_abnormal_imprinting0.20457137
158MP0003631_nervous_system_phenotype0.20198391
159MP0004134_abnormal_chest_morphology0.19385576
160MP0004019_abnormal_vitamin_homeostasis0.19050446
161MP0003045_fibrosis0.17744805
162MP0002736_abnormal_nociception_after0.17436155
163MP0005375_adipose_tissue_phenotype0.17322618
164MP0003959_abnormal_lean_body0.16676360
165MP0002080_prenatal_lethality0.16604211
166MP0003936_abnormal_reproductive_system0.16550688
167MP0004270_analgesia0.15899414
168MP0001440_abnormal_grooming_behavior0.15710087
169MP0000001_mammalian_phenotype0.15653690

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.11273775
2Abnormal respiratory motile cilium morphology (HP:0005938)8.95966472
3Abnormal respiratory epithelium morphology (HP:0012253)8.95966472
4Rhinitis (HP:0012384)7.73399249
5Chronic bronchitis (HP:0004469)7.19746771
6Abnormal ciliary motility (HP:0012262)7.01713661
7Infertility (HP:0000789)6.85419088
8Nasal polyposis (HP:0100582)6.44073616
9Parkinsonism with favorable response to dopaminergic medication (HP:0002548)5.99253043
10Abnormality of the nasal mucosa (HP:0000433)5.27557365
11Colitis (HP:0002583)4.65756740
12Bronchitis (HP:0012387)4.61502030
13Resting tremor (HP:0002322)4.58495809
14Nephronophthisis (HP:0000090)4.57158432
15Bronchiectasis (HP:0002110)4.55567431
16Male infertility (HP:0003251)4.28952035
17Hypoplasia of the thymus (HP:0000778)4.15121458
18Severe visual impairment (HP:0001141)3.89552862
19Postural instability (HP:0002172)3.46539373
20Abnormality of the renal medulla (HP:0100957)3.44942752
21Abnormal spermatogenesis (HP:0008669)3.43605928
22Recurrent otitis media (HP:0000403)3.37627970
23Gingivitis (HP:0000230)3.20023510
24Chronic hepatic failure (HP:0100626)3.13826035
25Recurrent sinusitis (HP:0011108)3.07830848
26Abnormality of the fingertips (HP:0001211)3.07793645
27Recurrent bacterial skin infections (HP:0005406)3.06297780
28Inflammation of the large intestine (HP:0002037)2.99204015
29Impulsivity (HP:0100710)2.99091178
30Asymmetric septal hypertrophy (HP:0001670)2.99069665
31Truncal obesity (HP:0001956)2.97515183
32Gonadotropin excess (HP:0000837)2.97122337
33Hyperkalemia (HP:0002153)2.93957844
34Recurrent bronchitis (HP:0002837)2.89338869
35Tubulointerstitial nephritis (HP:0001970)2.86365749
36Gastrointestinal inflammation (HP:0004386)2.85776257
37Recurrent abscess formation (HP:0002722)2.78029975
38Menstrual irregularities (HP:0000858)2.75004759
39Cellulitis (HP:0100658)2.72472707
40Bony spicule pigmentary retinopathy (HP:0007737)2.70877629
41Tubular atrophy (HP:0000092)2.70731898
42Abnormality of the lower motor neuron (HP:0002366)2.69399537
43Attenuation of retinal blood vessels (HP:0007843)2.66401876
44Abnormality of midbrain morphology (HP:0002418)2.63160000
45Molar tooth sign on MRI (HP:0002419)2.63160000
46IgA deficiency (HP:0002720)2.57592649
47Renovascular hypertension (HP:0100817)2.56361410
48Sandal gap (HP:0001852)2.53951537
49Aplasia/Hypoplasia of the thymus (HP:0010515)2.53188340
50Aplasia/Hypoplasia of the earlobes (HP:0009906)2.52678199
51Tubulointerstitial abnormality (HP:0001969)2.51146476
52Cone-rod dystrophy (HP:0000548)2.48264098
53Sensory axonal neuropathy (HP:0003390)2.47122251
54IgM deficiency (HP:0002850)2.44297814
55Abnormality of the columella (HP:0009929)2.41381545
56Bowel incontinence (HP:0002607)2.38839692
57Neoplasm of the heart (HP:0100544)2.38657539
58Thyroiditis (HP:0100646)2.36863338
59Medial flaring of the eyebrow (HP:0010747)2.36496292
60Slow saccadic eye movements (HP:0000514)2.35210887
61Azoospermia (HP:0000027)2.31252469
62Abnormal large intestine physiology (HP:0012700)2.30372065
63T lymphocytopenia (HP:0005403)2.28897880
64Hepatitis (HP:0012115)2.28796968
65Abnormal gallbladder physiology (HP:0012438)2.26759400
66Cholecystitis (HP:0001082)2.26759400
67Recurrent viral infections (HP:0004429)2.26587831
68Recurrent fungal infections (HP:0002841)2.25900908
69Amyotrophic lateral sclerosis (HP:0007354)2.22333155
70Hypoplasia of the capital femoral epiphysis (HP:0003090)2.17807477
71Spastic tetraparesis (HP:0001285)2.17372235
72Eczematoid dermatitis (HP:0000976)2.16130456
73Abnormality of the thymus (HP:0000777)2.15549222
74Abnormality of the distal phalanx of the thumb (HP:0009617)2.15244142
75Glucose intolerance (HP:0000833)2.14038463
76Recurrent skin infections (HP:0001581)2.10330430
77Tubulointerstitial fibrosis (HP:0005576)2.07325212
78Gastrointestinal infarctions (HP:0005244)2.07005807
79Prominent nose (HP:0000448)2.03269002
80Interstitial pulmonary disease (HP:0006530)2.03200682
81Abnormality of T cell number (HP:0011839)2.03049641
82Postaxial foot polydactyly (HP:0001830)2.02712445
83Dysmetric saccades (HP:0000641)2.01469542
84Spontaneous hematomas (HP:0007420)2.00947835
85Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2000967
86Dynein arm defect of respiratory motile cilia (HP:0012255)12.8879913
87Absent/shortened dynein arms (HP:0200106)12.8879913
88Heterotopia (HP:0002282)1.98878697
89Portal hypertension (HP:0001409)1.98562368
90Dyschromatopsia (HP:0007641)1.96842921
91Fatigue (HP:0012378)1.96496551
92Stage 5 chronic kidney disease (HP:0003774)1.94064568
93Viral hepatitis (HP:0006562)1.93181060
94Progressive sensorineural hearing impairment (HP:0000408)1.92166400
95Abnormality of the hepatic vasculature (HP:0006707)1.91097758
96Fibular hypoplasia (HP:0003038)1.90833363
97Panhypogammaglobulinemia (HP:0003139)1.89669920
98Acute myeloid leukemia (HP:0004808)1.87433566
99Polydipsia (HP:0001959)1.86095250
100Abnormal drinking behavior (HP:0030082)1.86095250
101Choroideremia (HP:0001139)1.85804365
102Short ribs (HP:0000773)1.84029113
103Chronic obstructive pulmonary disease (HP:0006510)1.83959999
104Obstructive lung disease (HP:0006536)1.83959999
105Germ cell neoplasia (HP:0100728)1.83298356
106Congenital hepatic fibrosis (HP:0002612)1.83212351
107Recurrent cutaneous fungal infections (HP:0011370)1.81907755
108Chronic mucocutaneous candidiasis (HP:0002728)1.81907755
109Impaired proprioception (HP:0010831)1.79119443
110Spinal cord lesions (HP:0100561)1.77870955
111Syringomyelia (HP:0003396)1.77870955
112Abnormality of DNA repair (HP:0003254)1.77784122
113Broad face (HP:0000283)1.77618223
114Abnormality of the parietal bone (HP:0002696)1.77310600
115Acute lymphatic leukemia (HP:0006721)1.76842723
116Acute hepatic failure (HP:0006554)1.76176118
117Abnormality of T cells (HP:0002843)1.75841536
118Bell-shaped thorax (HP:0001591)1.74655582
119Short 4th metacarpal (HP:0010044)1.74086397
120Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.74086397
121Subacute progressive viral hepatitis (HP:0006572)1.73677458
122Abnormality of the renal cortex (HP:0011035)1.73400644
123Oculomotor apraxia (HP:0000657)1.72547861
124Absent epiphyses (HP:0010577)1.71361343
125Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.71361343
126Autoimmune thrombocytopenia (HP:0001973)1.70877790
127Abnormal glucose tolerance (HP:0001952)1.70760748
128Progressive hearing impairment (HP:0001730)1.70578080
129Enlarged epiphyses (HP:0010580)1.70301052
130Renal dysplasia (HP:0000110)1.69871207
131Obsessive-compulsive behavior (HP:0000722)1.69612999
132Ureteral obstruction (HP:0006000)1.69064370
133Recurrent pneumonia (HP:0006532)1.67586268
134Hypoplastic ischia (HP:0003175)1.66822472
135Hypergonadotropic hypogonadism (HP:0000815)1.64131121
136Short nail (HP:0001799)1.63487015
137Medulloblastoma (HP:0002885)1.61831054
138Flattened epiphyses (HP:0003071)1.60916825
139Abnormality of dentin (HP:0010299)1.58706477
140Abnormality of renal excretion (HP:0011036)1.58445401
141Absent frontal sinuses (HP:0002688)1.58259093
142Abnormality of permanent molar morphology (HP:0011071)1.56589303
143Abnormality of the dental root (HP:0006486)1.56589303
144Taurodontia (HP:0000679)1.56589303
145Decreased central vision (HP:0007663)1.56435404
146Facial cleft (HP:0002006)1.53668436
147Postaxial hand polydactyly (HP:0001162)1.51987684
148Abnormal biliary tract physiology (HP:0012439)1.50590270
149Bile duct proliferation (HP:0001408)1.50590270
150J-shaped sella turcica (HP:0002680)1.48186644
151Deformed sella turcica (HP:0002681)1.47995691
152Microglossia (HP:0000171)1.45243396
153Abnormality of molar morphology (HP:0011070)1.44458935
154Abnormality of molar (HP:0011077)1.44458935
155Short thorax (HP:0010306)1.42445435
156Hemorrhage of the eye (HP:0011885)1.42337317
157Abnormality of the dental pulp (HP:0006479)1.42156176
158Neurofibrillary tangles (HP:0002185)1.41507616
159Hemiparesis (HP:0001269)1.40934160
160Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.39468529
161Broad distal phalanx of finger (HP:0009836)1.38829602
162Upper motor neuron abnormality (HP:0002127)1.36906537
163Supernumerary spleens (HP:0009799)1.34331172
164Cerebellar dysplasia (HP:0007033)1.32569190
165Short femoral neck (HP:0100864)1.32308383
166Aplasia/Hypoplasia of the lens (HP:0008063)1.32229211
167Chronic sinusitis (HP:0011109)1.31886917
168Cystic liver disease (HP:0006706)1.31832562
169Abnormal urine output (HP:0012590)1.30851830
170Nephropathy (HP:0000112)1.29927089
171Abnormality of the anterior horn cell (HP:0006802)1.27927102
172Degeneration of anterior horn cells (HP:0002398)1.27927102
173Decreased electroretinogram (ERG) amplitude (HP:0000654)1.27760936
174Median cleft lip (HP:0000161)1.27135806
175Abnormality of ocular smooth pursuit (HP:0000617)1.26554959
176Pachygyria (HP:0001302)1.25626845
177Loss of speech (HP:0002371)1.17877893
178Cerebral inclusion bodies (HP:0100314)1.17710076
179Bundle branch block (HP:0011710)1.17646225
180Aplasia/Hypoplasia of the tongue (HP:0010295)1.16966494
181Decreased motor nerve conduction velocity (HP:0003431)1.16095461
182Difficulty climbing stairs (HP:0003551)1.15652874
183Gait imbalance (HP:0002141)1.15094942
184Congenital primary aphakia (HP:0007707)1.15052218

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK47.80422278
2PDK37.80422278
3TESK16.55559229
4PRKD35.73021240
5PDK25.02069579
6ICK4.49464899
7BRD43.34917853
8ZAK2.55860255
9TLK12.45389164
10PTK2B2.41600584
11PNCK2.33772859
12CAMK1D2.18798980
13WNK42.18227039
14STK392.05696205
15NEK22.01014857
16STK381.98500124
17PIK3CG1.84166776
18BTK1.62228788
19PKN21.60215137
20BLK1.56610907
21MAP2K31.46183984
22RPS6KA51.44538367
23DYRK1B1.44312278
24MAP3K21.42955721
25GRK61.36603070
26AKT31.34765083
27MAP4K11.34687122
28DDR21.32541149
29KSR21.21452770
30MAPK111.21278222
31STK41.18405472
32SMG11.16323835
33CAMKK21.11329441
34MAP3K11.11097960
35MST1R1.10534060
36CDK71.08465926
37TNK21.04250349
38TYRO31.02999685
39INSRR1.00361133
40PDK10.99670857
41MAP3K110.99044452
42SYK0.96184015
43DYRK30.95697426
44TAOK30.95646677
45MAPK150.95274906
46WNK10.93530755
47PASK0.92592598
48FES0.92044853
49HCK0.90673564
50TEC0.88841478
51MAP3K130.88694244
52STK30.85889287
53RET0.85811674
54CAMK40.84507378
55MAP3K80.82670769
56ITK0.82512528
57SIK20.78479787
58JAK30.76960411
59CCNB10.73227328
60SGK30.71854604
61TTK0.71266012
62PLK20.68803473
63RPS6KC10.66897307
64RPS6KL10.66897307
65SCYL20.65859918
66EEF2K0.64822196
67CAMK1G0.64674818
68FGFR30.64039155
69FRK0.63811877
70TESK20.63640810
71RPS6KA20.63202685
72PRPF4B0.62802527
73SGK20.61539611
74RPS6KA60.60547761
75MAP2K20.60182638
76CHEK20.59996016
77PINK10.58904336
78MELK0.56575445
79PDPK10.56264013
80CDC70.53500712
81IRAK10.53298326
82JAK20.52965128
83TYK20.52636722
84TTN0.52568303
85CSK0.52232067
86VRK10.52081558
87WEE10.49041895
88TRPM70.48599749
89CDK80.48042087
90SGK4940.47633462
91SGK2230.47633462
92CHEK10.46771922
93JAK10.46481086
94LCK0.44462243
95IKBKE0.43508444
96RIPK40.42990005
97MAP2K40.42788552
98STK38L0.42370165
99ATR0.41254297
100NTRK20.40474997
101PAK10.40253952
102MAP2K60.39490075
103PRKAA20.39037387
104MTOR0.37385192
105MUSK0.36289321
106LMTK20.34266269
107ATM0.34183047
108PAK20.31758289
109IRAK20.29202245
110CAMKK10.28154265
111PRKAA10.26272679
112PRKCG0.26150968
113MARK20.25064473
114PAK40.24741245
115PLK40.21972776
116PLK10.20981992
117NEK60.20181367
118RPS6KB10.19579119
119MAPKAPK50.19238309
120MAP3K100.17749542
121CDK120.15884648
122BMPR1B0.15375083
123PAK60.11694144
124TAOK10.11298074
125PRKCZ0.11018189
126BUB10.10708473
127CDK150.08207533
128CSNK1D0.07661695
129RPS6KA10.07393614
130CDK20.06964043
131GSK3B0.06545505
132BRSK20.06184894
133BRSK10.06135984
134STK110.06006870
135CDK180.05858299
136CDK10.05827422
137BRAF0.05653890
138CDK11A0.04730448
139PRKCQ0.04298888
140CSNK2A10.04113373
141MAP3K40.02706732
142CDK40.02444113
143MAPK80.01957287
144CDK140.01694154
145CSF1R0.01546347
146TRIB30.01405565
147AURKA0.01200887
148PRKACG0.01115821
149WNK30.00516320
150CDK60.00415446
151STK100.00074959
152ZAP70-0.0322668
153CLK1-0.0269457
154MARK3-0.0245603
155PIM1-0.0244248
156EGFR-0.0216017
157RPS6KA3-0.0154674
158PRKACB-0.0134811
159MAP3K5-0.0121561
160CAMK2A-0.0101932
161PRKG1-0.0065833
162CSNK2A2-0.0065392
163PRKCB-0.0047196
164PRKDC-0.0043874
165PDGFRB-0.0040002

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin B6 metabolism_Homo sapiens_hsa007504.17880226
2Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.15030587
3Fatty acid biosynthesis_Homo sapiens_hsa000614.00953178
4Pyruvate metabolism_Homo sapiens_hsa006203.66553647
5alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.87777305
6Linoleic acid metabolism_Homo sapiens_hsa005912.76350459
7Propanoate metabolism_Homo sapiens_hsa006402.75450014
8Glucagon signaling pathway_Homo sapiens_hsa049222.72884559
9Basal transcription factors_Homo sapiens_hsa030222.47838279
10Dorso-ventral axis formation_Homo sapiens_hsa043202.42778581
11Selenocompound metabolism_Homo sapiens_hsa004502.42086490
12Carbohydrate digestion and absorption_Homo sapiens_hsa049732.21574782
13Non-small cell lung cancer_Homo sapiens_hsa052232.15250480
14Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.14977679
15Glycerolipid metabolism_Homo sapiens_hsa005612.06830855
16Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.05872910
17Oocyte meiosis_Homo sapiens_hsa041141.99194082
18Fanconi anemia pathway_Homo sapiens_hsa034601.95756459
19Acute myeloid leukemia_Homo sapiens_hsa052211.94662523
20Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.93677389
21Pentose phosphate pathway_Homo sapiens_hsa000301.87476452
22Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.85655422
23Amphetamine addiction_Homo sapiens_hsa050311.77864667
24PPAR signaling pathway_Homo sapiens_hsa033201.76735912
25Glycerophospholipid metabolism_Homo sapiens_hsa005641.67628772
26Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.62373164
27Fructose and mannose metabolism_Homo sapiens_hsa000511.59495689
28Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.59014160
29Huntingtons disease_Homo sapiens_hsa050161.43353027
30Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.42648660
31Chronic myeloid leukemia_Homo sapiens_hsa052201.40769037
32mRNA surveillance pathway_Homo sapiens_hsa030151.39126936
33RNA transport_Homo sapiens_hsa030131.38509516
34mTOR signaling pathway_Homo sapiens_hsa041501.38006082
35Pancreatic cancer_Homo sapiens_hsa052121.35775682
36Fat digestion and absorption_Homo sapiens_hsa049751.33723890
37Osteoclast differentiation_Homo sapiens_hsa043801.32868811
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.30303828
39Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.29634271
40Carbon metabolism_Homo sapiens_hsa012001.28348015
41Glioma_Homo sapiens_hsa052141.28185313
42Cardiac muscle contraction_Homo sapiens_hsa042601.27442898
43T cell receptor signaling pathway_Homo sapiens_hsa046601.26573644
44Leishmaniasis_Homo sapiens_hsa051401.26521802
45Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.25505353
46Transcriptional misregulation in cancer_Homo sapiens_hsa052021.24184274
47Ether lipid metabolism_Homo sapiens_hsa005651.23993587
48Renin secretion_Homo sapiens_hsa049241.23781810
49Platelet activation_Homo sapiens_hsa046111.22891899
50Influenza A_Homo sapiens_hsa051641.22132184
51Fatty acid metabolism_Homo sapiens_hsa012121.20629261
52Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.19026223
53Endometrial cancer_Homo sapiens_hsa052131.17644513
54Olfactory transduction_Homo sapiens_hsa047401.14275887
55Type II diabetes mellitus_Homo sapiens_hsa049301.12897216
56Fatty acid degradation_Homo sapiens_hsa000711.12341610
57Antigen processing and presentation_Homo sapiens_hsa046121.11777911
58Graft-versus-host disease_Homo sapiens_hsa053321.09644234
59Glycosaminoglycan degradation_Homo sapiens_hsa005311.09606532
60Autoimmune thyroid disease_Homo sapiens_hsa053201.07890372
61Allograft rejection_Homo sapiens_hsa053301.07331597
62Mineral absorption_Homo sapiens_hsa049781.06672562
63Prolactin signaling pathway_Homo sapiens_hsa049171.05110126
64Toxoplasmosis_Homo sapiens_hsa051451.03820337
65Measles_Homo sapiens_hsa051621.00058218
66Hepatitis B_Homo sapiens_hsa051610.99518015
67Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.97864745
68Purine metabolism_Homo sapiens_hsa002300.97832850
69Long-term potentiation_Homo sapiens_hsa047200.95670219
70Prostate cancer_Homo sapiens_hsa052150.95037957
71Herpes simplex infection_Homo sapiens_hsa051680.94865759
72ErbB signaling pathway_Homo sapiens_hsa040120.92914750
73Apoptosis_Homo sapiens_hsa042100.92165487
74RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.91865069
75NF-kappa B signaling pathway_Homo sapiens_hsa040640.91795026
76Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.91602448
77Primary immunodeficiency_Homo sapiens_hsa053400.91418303
78AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.89430208
79Systemic lupus erythematosus_Homo sapiens_hsa053220.88789794
80Tuberculosis_Homo sapiens_hsa051520.87338146
81Colorectal cancer_Homo sapiens_hsa052100.86804958
82Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.86496079
83Hedgehog signaling pathway_Homo sapiens_hsa043400.85341617
84Toll-like receptor signaling pathway_Homo sapiens_hsa046200.84867697
85FoxO signaling pathway_Homo sapiens_hsa040680.84858683
86Jak-STAT signaling pathway_Homo sapiens_hsa046300.83236744
87Estrogen signaling pathway_Homo sapiens_hsa049150.82560714
88Neurotrophin signaling pathway_Homo sapiens_hsa047220.82474899
89Choline metabolism in cancer_Homo sapiens_hsa052310.81003196
90Sphingolipid signaling pathway_Homo sapiens_hsa040710.80505200
91Glutathione metabolism_Homo sapiens_hsa004800.79584581
92Viral myocarditis_Homo sapiens_hsa054160.79559161
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.78503788
94Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.78417096
95Biosynthesis of amino acids_Homo sapiens_hsa012300.75170894
96Adipocytokine signaling pathway_Homo sapiens_hsa049200.75007162
97Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.72388394
98Lysine degradation_Homo sapiens_hsa003100.71186560
99Central carbon metabolism in cancer_Homo sapiens_hsa052300.70669091
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.68562395
101Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.68333368
102Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.67788236
103Thyroid cancer_Homo sapiens_hsa052160.66244751
104Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.64833313
105MicroRNAs in cancer_Homo sapiens_hsa052060.64413209
106Bladder cancer_Homo sapiens_hsa052190.64312419
107ABC transporters_Homo sapiens_hsa020100.64165936
108Notch signaling pathway_Homo sapiens_hsa043300.63966775
109Insulin secretion_Homo sapiens_hsa049110.63715698
110Type I diabetes mellitus_Homo sapiens_hsa049400.62997928
111Phospholipase D signaling pathway_Homo sapiens_hsa040720.62356803
112Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61124161
113Other glycan degradation_Homo sapiens_hsa005110.61120313
114HTLV-I infection_Homo sapiens_hsa051660.61074624
115Renal cell carcinoma_Homo sapiens_hsa052110.61006303
116Arachidonic acid metabolism_Homo sapiens_hsa005900.60758788
117AMPK signaling pathway_Homo sapiens_hsa041520.58682528
118Calcium signaling pathway_Homo sapiens_hsa040200.58509642
119MAPK signaling pathway_Homo sapiens_hsa040100.57227376
120NOD-like receptor signaling pathway_Homo sapiens_hsa046210.56907616
121Small cell lung cancer_Homo sapiens_hsa052220.56627736
122Alcoholism_Homo sapiens_hsa050340.56580867
123Collecting duct acid secretion_Homo sapiens_hsa049660.56146833
124Gap junction_Homo sapiens_hsa045400.55646492
125VEGF signaling pathway_Homo sapiens_hsa043700.54907870
126TNF signaling pathway_Homo sapiens_hsa046680.54686024
127Epstein-Barr virus infection_Homo sapiens_hsa051690.54018008
128Thyroid hormone synthesis_Homo sapiens_hsa049180.53096497
129Legionellosis_Homo sapiens_hsa051340.52745977
130Chemokine signaling pathway_Homo sapiens_hsa040620.52726173
131Insulin resistance_Homo sapiens_hsa049310.52109169
132Endocytosis_Homo sapiens_hsa041440.51864751
133Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.49260651
134Melanoma_Homo sapiens_hsa052180.48876724
135Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48258014
136Bile secretion_Homo sapiens_hsa049760.47817138
137Chemical carcinogenesis_Homo sapiens_hsa052040.47373737
138Insulin signaling pathway_Homo sapiens_hsa049100.43398615
139Inositol phosphate metabolism_Homo sapiens_hsa005620.43392546
140Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.43163455
141Staphylococcus aureus infection_Homo sapiens_hsa051500.43024914
142Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42463486
143Cholinergic synapse_Homo sapiens_hsa047250.42446118
144Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42084266
145Renin-angiotensin system_Homo sapiens_hsa046140.39861735
146Thyroid hormone signaling pathway_Homo sapiens_hsa049190.39533500
147Taste transduction_Homo sapiens_hsa047420.38851721
148Pancreatic secretion_Homo sapiens_hsa049720.37715380
149Synaptic vesicle cycle_Homo sapiens_hsa047210.36863027
150Vascular smooth muscle contraction_Homo sapiens_hsa042700.35942545
151Circadian entrainment_Homo sapiens_hsa047130.35155963
152Salivary secretion_Homo sapiens_hsa049700.32939411
153Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.31860751
154Cocaine addiction_Homo sapiens_hsa050300.31224024
155Protein digestion and absorption_Homo sapiens_hsa049740.31138110
156RNA degradation_Homo sapiens_hsa030180.30430158
157cAMP signaling pathway_Homo sapiens_hsa040240.29593783
158Metabolic pathways_Homo sapiens_hsa011000.28616199
159Pyrimidine metabolism_Homo sapiens_hsa002400.28138788
160Viral carcinogenesis_Homo sapiens_hsa052030.28083556
161Gastric acid secretion_Homo sapiens_hsa049710.25740105
162N-Glycan biosynthesis_Homo sapiens_hsa005100.25416646
163Basal cell carcinoma_Homo sapiens_hsa052170.21709576
164Wnt signaling pathway_Homo sapiens_hsa043100.19890743
165Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.19049549
166Longevity regulating pathway - mammal_Homo sapiens_hsa042110.17400623
167B cell receptor signaling pathway_Homo sapiens_hsa046620.16797902
168Cell cycle_Homo sapiens_hsa041100.15911538
169Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.13975733
170HIF-1 signaling pathway_Homo sapiens_hsa040660.13360569

Most similar genes based on co-expression Upload to Enrichr

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