RIMKLB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)4.99924379
2neuron cell-cell adhesion (GO:0007158)4.39907119
3cell migration in hindbrain (GO:0021535)4.03463692
4microtubule depolymerization (GO:0007019)3.72576284
5epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.70953893
6layer formation in cerebral cortex (GO:0021819)3.67765685
7limb bud formation (GO:0060174)3.61636784
8nucleobase catabolic process (GO:0046113)3.60945670
9negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.56416897
10negative regulation of translation, ncRNA-mediated (GO:0040033)3.56416897
11regulation of translation, ncRNA-mediated (GO:0045974)3.56416897
12central nervous system projection neuron axonogenesis (GO:0021952)3.49488101
13vocalization behavior (GO:0071625)3.48873703
14neuron recognition (GO:0008038)3.44494676
15positive regulation of synapse maturation (GO:0090129)3.39961826
16regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.35842480
17somite development (GO:0061053)3.31646332
18regulation of short-term neuronal synaptic plasticity (GO:0048172)3.30811260
19regulation of development, heterochronic (GO:0040034)3.22908737
20axonal fasciculation (GO:0007413)3.20418484
21regulation of timing of cell differentiation (GO:0048505)3.18336734
22microtubule severing (GO:0051013)3.14308858
23protein localization to synapse (GO:0035418)3.14030466
24regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.13774472
25proline transport (GO:0015824)3.13770058
26piRNA metabolic process (GO:0034587)3.12518121
27DNA double-strand break processing (GO:0000729)3.09820120
28regulation of telomere maintenance via telomerase (GO:0032210)3.07784148
29kidney morphogenesis (GO:0060993)3.03928711
30hippocampus development (GO:0021766)3.03174890
31synaptic vesicle maturation (GO:0016188)2.97347292
32regulation of cilium movement (GO:0003352)2.95523336
33regulation of glutamate receptor signaling pathway (GO:1900449)2.94945701
34dendritic spine morphogenesis (GO:0060997)2.91139359
35cerebral cortex radially oriented cell migration (GO:0021799)2.91035905
36positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.90003214
37histone arginine methylation (GO:0034969)2.89321429
38neural tube formation (GO:0001841)2.88945639
39postsynaptic membrane organization (GO:0001941)2.88867959
40histone H4-K5 acetylation (GO:0043981)2.88246592
41histone H4-K8 acetylation (GO:0043982)2.88246592
42peptidyl-arginine methylation (GO:0018216)2.87001345
43peptidyl-arginine N-methylation (GO:0035246)2.87001345
44retinal ganglion cell axon guidance (GO:0031290)2.86057166
45mechanosensory behavior (GO:0007638)2.85638541
46epithelial cilium movement (GO:0003351)2.83988974
47regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.81114793
48axon extension (GO:0048675)2.80431766
49dendrite morphogenesis (GO:0048813)2.78769151
50prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.77702423
51intraciliary transport (GO:0042073)2.77081278
52positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.76917440
53mitochondrion transport along microtubule (GO:0047497)2.76528167
54establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.76528167
55mitotic sister chromatid segregation (GO:0000070)2.76161526
56establishment of mitochondrion localization (GO:0051654)2.74710440
57C4-dicarboxylate transport (GO:0015740)2.73614700
58nonmotile primary cilium assembly (GO:0035058)2.73526914
59regulation of synapse maturation (GO:0090128)2.73193108
60histone H4-K12 acetylation (GO:0043983)2.72004694
61peptidyl-arginine omega-N-methylation (GO:0035247)2.71585923
62brain morphogenesis (GO:0048854)2.71261723
63spinal cord development (GO:0021510)2.71036167
64atrial cardiac muscle cell action potential (GO:0086014)2.68393918
65neurotransmitter-gated ion channel clustering (GO:0072578)2.68151082
66presynaptic membrane assembly (GO:0097105)2.67930866
67prostate gland growth (GO:0060736)2.67838215
68neuron fate determination (GO:0048664)2.67504547
69pre-miRNA processing (GO:0031054)2.65901144
70forebrain neuron differentiation (GO:0021879)2.65692399
71otic vesicle formation (GO:0030916)2.63926861
72head development (GO:0060322)2.63740807
73synaptic transmission, glutamatergic (GO:0035249)2.63464479
74synaptic vesicle exocytosis (GO:0016079)2.62205891
75positive regulation of synapse assembly (GO:0051965)2.60463069
76hindbrain development (GO:0030902)2.60076040
77glutamate secretion (GO:0014047)2.59393779
78dendrite development (GO:0016358)2.59028719
79negative regulation of microtubule polymerization (GO:0031115)2.58375418
80central nervous system neuron axonogenesis (GO:0021955)2.58176557
81exploration behavior (GO:0035640)2.58002987
82male meiosis (GO:0007140)2.56440034
83ionotropic glutamate receptor signaling pathway (GO:0035235)2.56344959
84sister chromatid segregation (GO:0000819)2.56315519
85establishment of nucleus localization (GO:0040023)2.55980468
86cerebellar granule cell differentiation (GO:0021707)2.54709219
87regulation of synaptic vesicle exocytosis (GO:2000300)2.52785888
88regulation of meiosis I (GO:0060631)2.52382454
89somite rostral/caudal axis specification (GO:0032525)2.52075604
90behavioral response to ethanol (GO:0048149)2.50863260
91gamma-aminobutyric acid transport (GO:0015812)2.50790034
92cilium movement (GO:0003341)2.50124424
93cerebral cortex neuron differentiation (GO:0021895)2.49757464
94glutamate receptor signaling pathway (GO:0007215)2.49579564
95regulation of microtubule-based movement (GO:0060632)2.49174592
96locomotory exploration behavior (GO:0035641)2.48957047
97cilium morphogenesis (GO:0060271)2.47880073
98calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.47711987
99startle response (GO:0001964)2.47650853
100neuron projection extension (GO:1990138)2.47089911
101protein polyglutamylation (GO:0018095)2.46025727
102regulation of non-canonical Wnt signaling pathway (GO:2000050)2.45534212
103regulation of NFAT protein import into nucleus (GO:0051532)2.45487267
104negative regulation of neurotransmitter transport (GO:0051589)2.44297216
105negative regulation of transcription regulatory region DNA binding (GO:2000678)2.43931076
106cilium organization (GO:0044782)2.42820103
107behavioral fear response (GO:0001662)2.42567668
108behavioral defense response (GO:0002209)2.42567668
109DNA methylation involved in gamete generation (GO:0043046)2.41988666
110synapse assembly (GO:0007416)2.41471310
111cilium assembly (GO:0042384)2.40158203
112negative regulation of cytosolic calcium ion concentration (GO:0051481)2.39703685
113regulation of dendritic spine morphogenesis (GO:0061001)2.39569308
114histone H2A acetylation (GO:0043968)2.38905590
115appendage development (GO:0048736)2.38372083
116limb development (GO:0060173)2.38372083
117presynaptic membrane organization (GO:0097090)2.38308454
118response to pheromone (GO:0019236)2.38253201
119olfactory bulb development (GO:0021772)2.38059735
120cerebellum development (GO:0021549)2.37954825
121ventricular system development (GO:0021591)2.37247808
122behavioral response to nicotine (GO:0035095)2.36636837
123synaptonemal complex assembly (GO:0007130)2.36572028
124regulation of collateral sprouting (GO:0048670)2.36555311
125regulation of telomere maintenance (GO:0032204)2.36524560
126neuron-neuron synaptic transmission (GO:0007270)2.36227384
127parturition (GO:0007567)2.34926647
128regulation of synapse structural plasticity (GO:0051823)2.34365330
129auditory behavior (GO:0031223)2.33871568
130regulation of mammary gland epithelial cell proliferation (GO:0033599)2.33585742
131neuronal stem cell maintenance (GO:0097150)2.33375252
132synaptic vesicle docking involved in exocytosis (GO:0016081)2.32696908
133regulation of gene silencing by RNA (GO:0060966)2.32662698
134regulation of posttranscriptional gene silencing (GO:0060147)2.32662698
135regulation of gene silencing by miRNA (GO:0060964)2.32662698
136regulation of nuclear cell cycle DNA replication (GO:0033262)2.32523106
137neurotransmitter secretion (GO:0007269)2.32291263
138positive regulation of dendritic spine morphogenesis (GO:0061003)2.32021940
139RNA localization (GO:0006403)2.31715775
140regulation of synaptic vesicle transport (GO:1902803)2.31634463
141generation of neurons (GO:0048699)2.30693076
142regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.29834809
143retinal cone cell development (GO:0046549)2.29620922
144cerebral cortex development (GO:0021987)2.29476195
145protein localization to kinetochore (GO:0034501)2.29476153
146translesion synthesis (GO:0019985)2.29463322
147synaptonemal complex organization (GO:0070193)2.29195590
148notochord development (GO:0030903)2.29093547
149detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.27956486
150cochlea development (GO:0090102)2.27312834
151mRNA splice site selection (GO:0006376)2.27112900
152innervation (GO:0060384)2.26703322
153G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.26430409
154cilium or flagellum-dependent cell motility (GO:0001539)2.26286145
155negative regulation of DNA-dependent DNA replication (GO:2000104)2.25462694
156cornea development in camera-type eye (GO:0061303)2.24613478
157cerebral cortex cell migration (GO:0021795)2.23662373
158negative regulation of dendrite development (GO:2000171)2.23305949
159regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.22434703
160cellular response to cholesterol (GO:0071397)2.21564673
161negative regulation of oligodendrocyte differentiation (GO:0048715)2.21291662
162regulation of pigment cell differentiation (GO:0050932)2.20803409
163cellular response to sterol (GO:0036315)2.20712912
164transmission of nerve impulse (GO:0019226)2.20144238
165positive regulation of developmental pigmentation (GO:0048087)2.20010683
166negative regulation of astrocyte differentiation (GO:0048712)2.19365258
167dorsal/ventral axis specification (GO:0009950)2.19239883
168sympathetic nervous system development (GO:0048485)2.18332702

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.67219422
2GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.00119803
3NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.66713883
4CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.64467267
5GBX2_23144817_ChIP-Seq_PC3_Human2.43649301
6ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.42237218
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.36463679
8EWS_26573619_Chip-Seq_HEK293_Human2.31835518
9SALL1_21062744_ChIP-ChIP_HESCs_Human2.30177320
10CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.25379606
11GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.23521189
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.20112517
13TP63_19390658_ChIP-ChIP_HaCaT_Human2.19273360
14* RNF2_27304074_Chip-Seq_NSC_Mouse2.15586296
15REST_21632747_ChIP-Seq_MESCs_Mouse2.12538952
16MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.03665222
17EZH2_27304074_Chip-Seq_ESCs_Mouse1.93669509
18AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.90014925
19CBX2_27304074_Chip-Seq_ESCs_Mouse1.89103430
20PIAS1_25552417_ChIP-Seq_VCAP_Human1.80570353
21JARID2_20064375_ChIP-Seq_MESCs_Mouse1.78915532
22NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.78383228
23POU5F1_16153702_ChIP-ChIP_HESCs_Human1.75141746
24MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.74821273
25SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.74684307
26OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.73769516
27SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.73331200
28SMAD3_21741376_ChIP-Seq_EPCs_Human1.71283384
29SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.71105996
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.69117049
31KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.67293250
32KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.67293250
33KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.67293250
34SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.65528977
35SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.64883690
36SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.63405841
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.62904959
38RNF2_27304074_Chip-Seq_ESCs_Mouse1.59945399
39* BMI1_23680149_ChIP-Seq_NPCS_Mouse1.57908085
40RNF2_18974828_ChIP-Seq_MESCs_Mouse1.56529740
41EZH2_18974828_ChIP-Seq_MESCs_Mouse1.56529740
42IGF1R_20145208_ChIP-Seq_DFB_Human1.54683850
43* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.53824047
44UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.51396580
45MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.51084968
46NR3C1_21868756_ChIP-Seq_MCF10A_Human1.49011172
47FLI1_27457419_Chip-Seq_LIVER_Mouse1.46250932
48AR_25329375_ChIP-Seq_VCAP_Human1.45390300
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.44432510
50CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.43340454
51ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.41868829
52FUS_26573619_Chip-Seq_HEK293_Human1.40677013
53SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40633030
54NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.40076566
55IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39029950
56CBP_20019798_ChIP-Seq_JUKART_Human1.39029950
57GATA1_26923725_Chip-Seq_HPCs_Mouse1.38698809
58RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.38353105
59TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38333318
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38333318
61JARID2_20075857_ChIP-Seq_MESCs_Mouse1.38055327
62RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.37443710
63RUNX2_22187159_ChIP-Seq_PCA_Human1.36912135
64SOX2_18555785_ChIP-Seq_MESCs_Mouse1.36752174
65SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.36704499
66AR_21572438_ChIP-Seq_LNCaP_Human1.36336243
67TCF4_23295773_ChIP-Seq_U87_Human1.36081737
68RARB_27405468_Chip-Seq_BRAIN_Mouse1.34873577
69* EZH2_27294783_Chip-Seq_ESCs_Mouse1.33014390
70ZFP57_27257070_Chip-Seq_ESCs_Mouse1.32281414
71EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.30812493
72TAF15_26573619_Chip-Seq_HEK293_Human1.30464475
73ER_23166858_ChIP-Seq_MCF-7_Human1.30084564
74RING1B_27294783_Chip-Seq_NPCs_Mouse1.29090560
75FOXM1_23109430_ChIP-Seq_U2OS_Human1.28162232
76TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.26488128
77MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.25642104
78BCAT_22108803_ChIP-Seq_LS180_Human1.25556709
79SOX2_16153702_ChIP-ChIP_HESCs_Human1.24187792
80HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.23515152
81TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.23438707
82SUZ12_27294783_Chip-Seq_ESCs_Mouse1.22807594
83CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.22746226
84TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.21934536
85SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.21453396
86KLF5_20875108_ChIP-Seq_MESCs_Mouse1.20193162
87BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.20148040
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.20128179
89TCF3_18692474_ChIP-Seq_MESCs_Mouse1.19634358
90ZFP281_18757296_ChIP-ChIP_E14_Mouse1.18568004
91TCF4_22108803_ChIP-Seq_LS180_Human1.18511953
92NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.18437740
93SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.17333697
94PCGF2_27294783_Chip-Seq_ESCs_Mouse1.15874657
95KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.14444538
96ELK4_26923725_Chip-Seq_MESODERM_Mouse1.14272755
97* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.13095797
98TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.12688132
99EED_16625203_ChIP-ChIP_MESCs_Mouse1.12184698
100POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.11896040
101EZH2_27294783_Chip-Seq_NPCs_Mouse1.11670537
102ZNF274_21170338_ChIP-Seq_K562_Hela1.11572231
103FLI1_21867929_ChIP-Seq_TH2_Mouse1.10614727
104SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.10117518
105SMAD4_21799915_ChIP-Seq_A2780_Human1.07466385
106EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05641232
107TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.05366631
108MTF2_20144788_ChIP-Seq_MESCs_Mouse1.05317794
109LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05054083
110PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.04772999
111RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.04277730
112* RING1B_27294783_Chip-Seq_ESCs_Mouse1.04219802
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.03703391
114CDX2_19796622_ChIP-Seq_MESCs_Mouse1.03413361
115HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.03374192
116VDR_22108803_ChIP-Seq_LS180_Human1.03249645
117POU5F1_16518401_ChIP-PET_MESCs_Mouse1.03184499
118TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02500981
119WT1_19549856_ChIP-ChIP_CCG9911_Human1.01785978
120POU3F2_20337985_ChIP-ChIP_501MEL_Human1.01426156
121FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.01050852
122MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.01012813
123TBX3_20139965_ChIP-Seq_ESCs_Mouse1.00999552
124TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.00914134
125JUN_21703547_ChIP-Seq_K562_Human1.00757523
126ZFP281_27345836_Chip-Seq_ESCs_Mouse1.00744599
127CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00622542
128PCGF2_27294783_Chip-Seq_NPCs_Mouse1.00462549
129* TAL1_26923725_Chip-Seq_HPCs_Mouse0.99802647
130STAT3_23295773_ChIP-Seq_U87_Human0.99778016
131TBX3_20139965_ChIP-Seq_MESCs_Mouse0.99592036
132STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.98952481
133TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98924045
134TP53_18474530_ChIP-ChIP_U2OS_Human0.98193499
135PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.97951408
136IRF1_19129219_ChIP-ChIP_H3396_Human0.97018919
137SUZ12_27294783_Chip-Seq_NPCs_Mouse0.96880122
138HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.96763819
139YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96745924
140SMAD4_21741376_ChIP-Seq_EPCs_Human0.96678615
141TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95986891
142P300_19829295_ChIP-Seq_ESCs_Human0.94940768
143SOX2_21211035_ChIP-Seq_LN229_Gbm0.94439888
144SOX9_26525672_Chip-Seq_HEART_Mouse0.94150766

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.05438845
2MP0004859_abnormal_synaptic_plasticity2.75473930
3MP0000778_abnormal_nervous_system2.64081317
4MP0005394_taste/olfaction_phenotype2.59844914
5MP0005499_abnormal_olfactory_system2.59844914
6MP0002653_abnormal_ependyma_morphology2.58838287
7MP0003880_abnormal_central_pattern2.56005125
8MP0005423_abnormal_somatic_nervous2.43062314
9MP0004270_analgesia2.37741091
10MP0003122_maternal_imprinting2.27338621
11MP0003121_genomic_imprinting2.25160013
12MP0003787_abnormal_imprinting2.24517418
13MP0003890_abnormal_embryonic-extraembry2.19199646
14MP0008789_abnormal_olfactory_epithelium2.14629879
15MP0003635_abnormal_synaptic_transmissio2.11366426
16MP0002063_abnormal_learning/memory/cond1.98278466
17MP0002734_abnormal_mechanical_nocicepti1.80410963
18MP0002184_abnormal_innervation1.79012053
19MP0006276_abnormal_autonomic_nervous1.74495342
20MP0008877_abnormal_DNA_methylation1.71528912
21MP0001486_abnormal_startle_reflex1.70758842
22MP0002572_abnormal_emotion/affect_behav1.67335872
23MP0002102_abnormal_ear_morphology1.66942905
24MP0003938_abnormal_ear_development1.65308016
25MP0004858_abnormal_nervous_system1.64736919
26MP0003123_paternal_imprinting1.61378771
27MP0001984_abnormal_olfaction1.59633587
28MP0003861_abnormal_nervous_system1.59115484
29MP0002234_abnormal_pharynx_morphology1.58481320
30MP0009046_muscle_twitch1.55856746
31MP0001529_abnormal_vocalization1.50493192
32MP0000631_abnormal_neuroendocrine_gland1.47680265
33MP0009745_abnormal_behavioral_response1.46844522
34MP0004885_abnormal_endolymph1.41817128
35MP0000955_abnormal_spinal_cord1.41664532
36MP0002557_abnormal_social/conspecific_i1.41126581
37MP0000537_abnormal_urethra_morphology1.39235841
38MP0002064_seizures1.38711866
39MP0003119_abnormal_digestive_system1.38585250
40MP0010030_abnormal_orbit_morphology1.38339010
41MP0005253_abnormal_eye_physiology1.35087195
42MP0001968_abnormal_touch/_nociception1.33437532
43MP0002152_abnormal_brain_morphology1.32602738
44MP0002160_abnormal_reproductive_system1.31717205
45MP0005187_abnormal_penis_morphology1.30518210
46MP0002254_reproductive_system_inflammat1.29662206
47MP0005248_abnormal_Harderian_gland1.27816743
48MP0002882_abnormal_neuron_morphology1.27502220
49MP0003755_abnormal_palate_morphology1.22860804
50MP0003698_abnormal_male_reproductive1.22337082
51MP0003315_abnormal_perineum_morphology1.22057737
52MP0004811_abnormal_neuron_physiology1.22044037
53MP0001440_abnormal_grooming_behavior1.21884382
54MP0002233_abnormal_nose_morphology1.19638152
55MP0000049_abnormal_middle_ear1.18707308
56MP0002733_abnormal_thermal_nociception1.18173982
57MP0004147_increased_porphyrin_level1.18036010
58MP0002697_abnormal_eye_size1.17221958
59MP0003937_abnormal_limbs/digits/tail_de1.16893668
60MP0002638_abnormal_pupillary_reflex1.16629860
61MP0002272_abnormal_nervous_system1.16578586
62MP0002752_abnormal_somatic_nervous1.16518012
63MP0005410_abnormal_fertilization1.16149300
64MP0002751_abnormal_autonomic_nervous1.15931101
65MP0004215_abnormal_myocardial_fiber1.15857772
66MP0003111_abnormal_nucleus_morphology1.14579740
67MP0005386_behavior/neurological_phenoty1.12104610
68MP0004924_abnormal_behavior1.12104610
69MP0005646_abnormal_pituitary_gland1.11813949
70MP0002067_abnormal_sensory_capabilities1.11781867
71MP0000647_abnormal_sebaceous_gland1.10946899
72MP0001177_atelectasis1.10634340
73MP0003567_abnormal_fetal_cardiomyocyte1.10486476
74MP0005645_abnormal_hypothalamus_physiol1.09654770
75MP0005367_renal/urinary_system_phenotyp1.09346535
76MP0000516_abnormal_urinary_system1.09346535
77MP0005391_vision/eye_phenotype1.09314297
78MP0001293_anophthalmia1.08715250
79MP0010386_abnormal_urinary_bladder1.07599728
80MP0001188_hyperpigmentation1.05840484
81MP0002210_abnormal_sex_determination1.05591182
82MP0002735_abnormal_chemical_nociception1.04794753
83MP0001299_abnormal_eye_distance/1.04515424
84MP0003136_yellow_coat_color1.03763541
85MP0000383_abnormal_hair_follicle1.03600026
86MP0000569_abnormal_digit_pigmentation1.03576905
87MP0001929_abnormal_gametogenesis1.02275878
88MP0009703_decreased_birth_body1.00945813
89MP0005195_abnormal_posterior_eye1.00237066
90MP0008057_abnormal_DNA_replication0.99974766
91MP0000566_synostosis0.99836386
92MP0003385_abnormal_body_wall0.99696200
93MP0001970_abnormal_pain_threshold0.98023200
94MP0002116_abnormal_craniofacial_bone0.97934268
95MP0002736_abnormal_nociception_after0.97707481
96MP0002928_abnormal_bile_duct0.96343236
97MP0006072_abnormal_retinal_apoptosis0.95350168
98MP0000026_abnormal_inner_ear0.95209877
99MP0002085_abnormal_embryonic_tissue0.94515278
100MP0002084_abnormal_developmental_patter0.92365863
101MP0004133_heterotaxia0.92217062
102MP0002081_perinatal_lethality0.91404687
103MP0008058_abnormal_DNA_repair0.90942237
104MP0003077_abnormal_cell_cycle0.90819727
105MP0002938_white_spotting0.89521821
106MP0003935_abnormal_craniofacial_develop0.88714935
107MP0001145_abnormal_male_reproductive0.88573306
108MP0003283_abnormal_digestive_organ0.88198139
109MP0010094_abnormal_chromosome_stability0.87655530
110MP0002066_abnormal_motor_capabilities/c0.87450115
111MP0001963_abnormal_hearing_physiology0.85155489
112MP0001485_abnormal_pinna_reflex0.84699904
113MP0003941_abnormal_skin_development0.84598783
114MP0003718_maternal_effect0.84185966
115MP0005380_embryogenesis_phenotype0.83763356
116MP0001672_abnormal_embryogenesis/_devel0.83763356
117MP0001286_abnormal_eye_development0.83593850
118MP0005389_reproductive_system_phenotype0.83536022
119MP0002249_abnormal_larynx_morphology0.83085528
120MP0002837_dystrophic_cardiac_calcinosis0.83022292
121MP0000428_abnormal_craniofacial_morphol0.81510633
122MP0002092_abnormal_eye_morphology0.81501136
123MP0000653_abnormal_sex_gland0.80423499
124MP0002161_abnormal_fertility/fecundity0.80059400
125MP0005551_abnormal_eye_electrophysiolog0.79947092
126MP0003942_abnormal_urinary_system0.79747608

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the lower motor neuron (HP:0002366)3.86044160
2Amyotrophic lateral sclerosis (HP:0007354)3.69967715
3Abnormality of the labia minora (HP:0012880)3.65315989
4Pancreatic cysts (HP:0001737)3.21815869
5True hermaphroditism (HP:0010459)3.19057402
6Hepatoblastoma (HP:0002884)3.04900521
7Bilateral microphthalmos (HP:0007633)2.98463116
8Nephronophthisis (HP:0000090)2.88782549
9Focal motor seizures (HP:0011153)2.81423293
10Colon cancer (HP:0003003)2.71395540
11Epileptic encephalopathy (HP:0200134)2.70623221
12Papillary thyroid carcinoma (HP:0002895)2.68297214
13Drooling (HP:0002307)2.60614163
14Excessive salivation (HP:0003781)2.60614163
15Hyperventilation (HP:0002883)2.56415119
16Abnormality of the renal medulla (HP:0100957)2.54946166
17Abnormality of the corticospinal tract (HP:0002492)2.51426673
18Vaginal atresia (HP:0000148)2.49434424
19Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.49322480
20Shawl scrotum (HP:0000049)2.48064031
21Chromosomal breakage induced by crosslinking agents (HP:0003221)2.45210598
22Focal seizures (HP:0007359)2.44028433
23Febrile seizures (HP:0002373)2.43433998
24Bifid tongue (HP:0010297)2.43348225
25Aplasia/Hypoplasia of the sternum (HP:0006714)2.42121258
26Volvulus (HP:0002580)2.39921778
27Absent eyebrow (HP:0002223)2.37854410
28Chronic hepatic failure (HP:0100626)2.36661404
29Facial hemangioma (HP:0000329)2.35617027
30Gait imbalance (HP:0002141)2.35134844
31Abnormality of the astrocytes (HP:0100707)2.30317887
32Astrocytoma (HP:0009592)2.30317887
33Supernumerary spleens (HP:0009799)2.30156722
34Postaxial foot polydactyly (HP:0001830)2.29996065
35Nephroblastoma (Wilms tumor) (HP:0002667)2.23678882
36Cystic liver disease (HP:0006706)2.20686210
37Cutaneous finger syndactyly (HP:0010554)2.19088616
38Anophthalmia (HP:0000528)2.18827226
39Cupped ear (HP:0000378)2.18054959
40Limb dystonia (HP:0002451)2.17224710
41Myokymia (HP:0002411)2.15617902
42Embryonal renal neoplasm (HP:0011794)2.15497101
43Impulsivity (HP:0100710)2.14985761
44Atrophy/Degeneration involving motor neurons (HP:0007373)2.12614527
45Intestinal atresia (HP:0011100)2.12073723
46Mutism (HP:0002300)2.11909750
47Renal hypoplasia (HP:0000089)2.10725376
48Optic nerve hypoplasia (HP:0000609)2.09929705
49Abnormality of chromosome segregation (HP:0002916)2.05662092
50Atonic seizures (HP:0010819)2.05538398
51Failure to thrive in infancy (HP:0001531)2.05186057
52Shoulder girdle muscle weakness (HP:0003547)2.04996064
53Preaxial hand polydactyly (HP:0001177)2.04701833
54Aqueductal stenosis (HP:0002410)2.04384162
55Ependymoma (HP:0002888)2.03737193
56Anencephaly (HP:0002323)2.03544156
57Occipital encephalocele (HP:0002085)2.00376695
58Amblyopia (HP:0000646)2.00102736
59Broad alveolar ridges (HP:0000187)1.99641656
60Chromsome breakage (HP:0040012)1.94788529
61Neoplasm of the adrenal cortex (HP:0100641)1.94537741
62Aplasia/Hypoplasia of the uvula (HP:0010293)1.92992952
63Preaxial foot polydactyly (HP:0001841)1.92625839
64Patellar aplasia (HP:0006443)1.92491403
65Sclerocornea (HP:0000647)1.92294560
66Progressive cerebellar ataxia (HP:0002073)1.92051465
67Rib fusion (HP:0000902)1.91370981
68Aplasia/Hypoplasia of the tongue (HP:0010295)1.90408062
69Thyroid-stimulating hormone excess (HP:0002925)1.90360969
70Dynein arm defect of respiratory motile cilia (HP:0012255)1.89638663
71Absent/shortened dynein arms (HP:0200106)1.89638663
72Scrotal hypoplasia (HP:0000046)1.89382134
73Molar tooth sign on MRI (HP:0002419)1.89381122
74Abnormality of midbrain morphology (HP:0002418)1.89381122
75Cerebellar dysplasia (HP:0007033)1.89223560
76Abnormal respiratory motile cilium physiology (HP:0012261)1.89052717
77Pendular nystagmus (HP:0012043)1.88095933
78Bile duct proliferation (HP:0001408)1.88050403
79Abnormal biliary tract physiology (HP:0012439)1.88050403
80Cutaneous syndactyly (HP:0012725)1.87962261
81High anterior hairline (HP:0009890)1.87424279
82Polyphagia (HP:0002591)1.86674328
83Protruding tongue (HP:0010808)1.86338825
84Broad-based gait (HP:0002136)1.86035484
85Absent speech (HP:0001344)1.85975301
86Micropenis (HP:0000054)1.84663193
87Type II lissencephaly (HP:0007260)1.84084279
88Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.82831321
89Aplasia/Hypoplasia of the patella (HP:0006498)1.82525067
90Abnormal lung lobation (HP:0002101)1.81973447
91Heterotopia (HP:0002282)1.80883801
92Specific learning disability (HP:0001328)1.80346584
93Hip dysplasia (HP:0001385)1.80320305
94Lissencephaly (HP:0001339)1.78159209
95Hemiparesis (HP:0001269)1.78081776
96Meckel diverticulum (HP:0002245)1.77869485
97Abnormality of the phalanges of the hallux (HP:0010057)1.77120767
98Narrow forehead (HP:0000341)1.75714136
99Tubulointerstitial nephritis (HP:0001970)1.75636168
100Glioma (HP:0009733)1.75514866
101Congenital primary aphakia (HP:0007707)1.74644651
102Medial flaring of the eyebrow (HP:0010747)1.73617176
103Embryonal neoplasm (HP:0002898)1.73503880
104Pachygyria (HP:0001302)1.73489850
105Morphological abnormality of the pyramidal tract (HP:0002062)1.73155442
106Abnormality of the ileum (HP:0001549)1.72622889
107Dandy-Walker malformation (HP:0001305)1.72605388
108Visual hallucinations (HP:0002367)1.71576503
109Abnormal respiratory motile cilium morphology (HP:0005938)1.71407553
110Abnormality of the renal cortex (HP:0011035)1.71213416
111Aplasia/Hypoplasia of the tibia (HP:0005772)1.70773604
112Septo-optic dysplasia (HP:0100842)1.70686749
113Congenital hepatic fibrosis (HP:0002612)1.70665899
114Dialeptic seizures (HP:0011146)1.70305458
115Generalized hypotonia (HP:0001290)1.69517229
116Large earlobe (HP:0009748)1.69474675
117Abnormal ciliary motility (HP:0012262)1.68610552
118Nephrogenic diabetes insipidus (HP:0009806)1.68387187
119Retinal dysplasia (HP:0007973)1.66794197
120Progressive inability to walk (HP:0002505)1.66762848
121Renal duplication (HP:0000075)1.66703927
122Hyperglycinemia (HP:0002154)1.65846847
123Midline defect of the nose (HP:0004122)1.65656215
124Thyroid carcinoma (HP:0002890)1.64560352
125Absence seizures (HP:0002121)1.64244738
126Neoplasm of the oral cavity (HP:0100649)1.63351946
127Inability to walk (HP:0002540)1.63022465
128Cortical dysplasia (HP:0002539)1.61897122
129Aplasia/Hypoplasia of the brainstem (HP:0007362)1.61084552
130Hypoplasia of the brainstem (HP:0002365)1.61084552
131Split foot (HP:0001839)1.61042710
132Oligodactyly (HP:0012165)1.60879443
133Pancreatic fibrosis (HP:0100732)1.60015915
134Ankle clonus (HP:0011448)1.59688969
135Poor coordination (HP:0002370)1.59446173
136Postaxial hand polydactyly (HP:0001162)1.58705778
137Short foot (HP:0001773)1.58279935
138Insidious onset (HP:0003587)1.57957172
139Termporal pattern (HP:0011008)1.57957172
140Gastroesophageal reflux (HP:0002020)1.57875699
141Abnormality of abdominal situs (HP:0011620)1.57791343
142Abdominal situs inversus (HP:0003363)1.57791343
143Gastrointestinal atresia (HP:0002589)1.57250897
144Abnormal social behavior (HP:0012433)1.56306601
145Impaired social interactions (HP:0000735)1.56306601
146Broad foot (HP:0001769)1.56101152
147Absent hair (HP:0002298)1.55832820
148Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.54742938
149Medulloblastoma (HP:0002885)1.53933571
150Abnormality of salivation (HP:0100755)1.53459620
151Genital tract atresia (HP:0001827)1.52594628
152Oligodactyly (hands) (HP:0001180)1.51737797
153Hypochromic microcytic anemia (HP:0004840)1.50481906
154Abnormal respiratory epithelium morphology (HP:0012253)1.50169369

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.71039859
2FRK3.32649424
3CASK2.81758761
4DYRK22.59186606
5NTRK22.55811635
6LATS22.54566026
7CDK122.51843809
8MAPK132.39126751
9AKT32.36421170
10MAP4K22.34405640
11MAP3K92.31409995
12BMPR1B2.30721548
13MAP3K42.25146178
14TYRO32.04949347
15TSSK62.01502263
16TNIK2.01462845
17MAP2K72.00828579
18NTRK31.97705629
19KSR11.75112329
20GRK51.72822555
21TRIM281.70058684
22MINK11.68238934
23NUAK11.63181736
24TIE11.60134086
25EPHA41.51241171
26MAPK151.50133222
27ERBB31.45925292
28PAK61.43094375
29WEE11.40063703
30MAP2K41.36861842
31ACVR1B1.28755645
32WNK31.27810047
33PRKD31.27620472
34CHEK21.26339102
35PNCK1.20715798
36SRPK11.19526964
37PHKG21.18770258
38PHKG11.18770258
39CDC71.17187193
40PLK21.17156157
41PDK21.14840130
42PLK31.13782895
43BCR1.12107410
44SIK21.11083657
45CSNK1G21.10628175
46STK391.07779923
47ZAK1.07715376
48PINK11.06985444
49OXSR11.06493192
50CCNB11.05407645
51INSRR1.04481315
52LATS11.03880453
53TTK1.03852764
54TGFBR11.02452408
55STK38L1.01968496
56PRPF4B1.01931597
57DYRK1A1.00314447
58MARK20.99132192
59PDK30.98043984
60PDK40.98043984
61CSNK1G30.97818004
62NLK0.94742988
63SGK20.91895779
64BUB10.91126355
65PLK10.90377278
66PIK3CA0.90055750
67MKNK20.88349988
68EPHB20.87593394
69ADRBK20.87340295
70UHMK10.86906430
71PRKCG0.85205346
72VRK10.84771674
73BRSK20.80925465
74SGK2230.80400617
75SGK4940.80400617
76MAP3K60.77647567
77CDK180.77264518
78CAMK1G0.77213551
79DAPK20.77132366
80PRKCE0.75198416
81CDK50.75057095
82BRAF0.74146533
83BRSK10.73187097
84CHEK10.73026441
85WNK40.72876617
86PLK40.72646368
87EPHA30.71397703
88CDK150.71337778
89MKNK10.71136546
90CSNK1A1L0.69956771
91ERBB40.69056055
92ICK0.68961374
93CDK140.67569557
94CDK30.66916180
95PRKCI0.66800659
96SIK30.66633274
97AURKA0.64892553
98YES10.62864351
99STK380.62243911
100CSNK1G10.61635001
101NEK20.60850351
102LIMK10.60633875
103CDK11A0.60396655
104PAK30.58458467
105CAMK40.56398472
106FGFR20.55982095
107CDK10.55413496
108CDK20.53625674
109PKN10.52892639
110EIF2AK30.50570728
111BRD40.50272827
112PRKCZ0.48211101
113GSK3B0.47548631
114ATR0.47023945
115MAPK100.46985571
116DYRK30.46983650
117CSNK1E0.46923133
118RPS6KA40.45986596
119CDK80.44030740
120CAMK2A0.43893397
121GRK70.43750644
122CSNK1A10.43556757
123PRKAA10.42567442
124SGK30.42266571
125STK30.42228853
126NEK10.41883388
127MAPKAPK50.41506101
128ATM0.41020477
129CSNK1D0.40401235
130PRKDC0.39518389
131GRK10.39157815
132NEK60.39026604
133ALK0.38937266
134ADRBK10.38607568
135PRKACB0.38133493
136CAMK1D0.34399769
137STK110.34295939
138SGK10.33012671
139FGFR10.31362054

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.24621021
2Vitamin B6 metabolism_Homo sapiens_hsa007502.62590271
3Synaptic vesicle cycle_Homo sapiens_hsa047212.32995760
4Axon guidance_Homo sapiens_hsa043602.19861625
5mRNA surveillance pathway_Homo sapiens_hsa030152.07460806
6GABAergic synapse_Homo sapiens_hsa047272.03017908
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.01933103
8Non-homologous end-joining_Homo sapiens_hsa034502.00144544
9Glutamatergic synapse_Homo sapiens_hsa047241.93087337
10Oocyte meiosis_Homo sapiens_hsa041141.92192210
11Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.83314757
12Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.78718538
13Selenocompound metabolism_Homo sapiens_hsa004501.75667489
14Dopaminergic synapse_Homo sapiens_hsa047281.71602482
15Long-term potentiation_Homo sapiens_hsa047201.66958284
16Taste transduction_Homo sapiens_hsa047421.66781624
17Propanoate metabolism_Homo sapiens_hsa006401.66668914
18Butanoate metabolism_Homo sapiens_hsa006501.65669731
19Basal transcription factors_Homo sapiens_hsa030221.64283813
20RNA transport_Homo sapiens_hsa030131.63517931
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.63215414
22Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.61399053
23Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.59694354
24Serotonergic synapse_Homo sapiens_hsa047261.59406827
25Olfactory transduction_Homo sapiens_hsa047401.58481304
26Cell cycle_Homo sapiens_hsa041101.57869789
27Circadian entrainment_Homo sapiens_hsa047131.57650921
28Morphine addiction_Homo sapiens_hsa050321.55027580
29Hedgehog signaling pathway_Homo sapiens_hsa043401.53574479
30Fanconi anemia pathway_Homo sapiens_hsa034601.53379474
31Steroid biosynthesis_Homo sapiens_hsa001001.49933241
32Basal cell carcinoma_Homo sapiens_hsa052171.48023230
33Amphetamine addiction_Homo sapiens_hsa050311.47341504
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.45705876
35Hippo signaling pathway_Homo sapiens_hsa043901.42456789
36Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.40129202
37Long-term depression_Homo sapiens_hsa047301.38366594
38Colorectal cancer_Homo sapiens_hsa052101.36680110
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.35329729
40RNA polymerase_Homo sapiens_hsa030201.34180712
41Endometrial cancer_Homo sapiens_hsa052131.30268885
42Wnt signaling pathway_Homo sapiens_hsa043101.27864823
43ErbB signaling pathway_Homo sapiens_hsa040121.27617143
44Protein export_Homo sapiens_hsa030601.27607978
45Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.25901254
46Spliceosome_Homo sapiens_hsa030401.23084204
47Cholinergic synapse_Homo sapiens_hsa047251.22619077
48Nitrogen metabolism_Homo sapiens_hsa009101.22543001
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.22506312
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.16961366
51Gap junction_Homo sapiens_hsa045401.16191238
52Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.15900341
53Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.13441397
54Cocaine addiction_Homo sapiens_hsa050301.13265618
55Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.08363263
56mTOR signaling pathway_Homo sapiens_hsa041501.05538988
57Melanogenesis_Homo sapiens_hsa049161.02094371
58Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.01885433
59Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.01660383
60Renal cell carcinoma_Homo sapiens_hsa052111.00186951
61Thyroid hormone signaling pathway_Homo sapiens_hsa049190.99622957
62GnRH signaling pathway_Homo sapiens_hsa049120.99335400
63Phototransduction_Homo sapiens_hsa047440.99081444
64Tryptophan metabolism_Homo sapiens_hsa003800.99071687
65RNA degradation_Homo sapiens_hsa030180.98412097
66Oxytocin signaling pathway_Homo sapiens_hsa049210.98279773
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.96633052
68Choline metabolism in cancer_Homo sapiens_hsa052310.94544808
69Dorso-ventral axis formation_Homo sapiens_hsa043200.93680462
70Insulin secretion_Homo sapiens_hsa049110.91368131
71Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.90032486
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88681858
73Mismatch repair_Homo sapiens_hsa034300.87456406
74alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.87279727
75Glioma_Homo sapiens_hsa052140.85656193
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.85448742
77Renin secretion_Homo sapiens_hsa049240.84601737
78Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.83825530
79Alcoholism_Homo sapiens_hsa050340.83778368
80Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.83758954
81Salivary secretion_Homo sapiens_hsa049700.82103172
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.81644136
83Estrogen signaling pathway_Homo sapiens_hsa049150.80300558
84Linoleic acid metabolism_Homo sapiens_hsa005910.80261918
85Calcium signaling pathway_Homo sapiens_hsa040200.79317614
86Tight junction_Homo sapiens_hsa045300.77356041
87cAMP signaling pathway_Homo sapiens_hsa040240.77266152
88Regulation of autophagy_Homo sapiens_hsa041400.77229070
89Collecting duct acid secretion_Homo sapiens_hsa049660.76816564
90MicroRNAs in cancer_Homo sapiens_hsa052060.76148516
91Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.73837942
92Lysine degradation_Homo sapiens_hsa003100.73651724
93MAPK signaling pathway_Homo sapiens_hsa040100.73000719
94Ras signaling pathway_Homo sapiens_hsa040140.71425505
95Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.70584952
96Aldosterone synthesis and secretion_Homo sapiens_hsa049250.69872265
97Ovarian steroidogenesis_Homo sapiens_hsa049130.68814694
98Fatty acid biosynthesis_Homo sapiens_hsa000610.68125242
99Nucleotide excision repair_Homo sapiens_hsa034200.67832376
100Phospholipase D signaling pathway_Homo sapiens_hsa040720.67094570
101Longevity regulating pathway - mammal_Homo sapiens_hsa042110.66967488
102Phosphatidylinositol signaling system_Homo sapiens_hsa040700.65327508
103TGF-beta signaling pathway_Homo sapiens_hsa043500.64401263
104Purine metabolism_Homo sapiens_hsa002300.63531873
105Notch signaling pathway_Homo sapiens_hsa043300.63452847
106beta-Alanine metabolism_Homo sapiens_hsa004100.63100740
107Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63066318
108Non-small cell lung cancer_Homo sapiens_hsa052230.60536004
109Gastric acid secretion_Homo sapiens_hsa049710.59220831
110Rap1 signaling pathway_Homo sapiens_hsa040150.58890812
111Melanoma_Homo sapiens_hsa052180.58354585
112Fatty acid metabolism_Homo sapiens_hsa012120.56960622
113Peroxisome_Homo sapiens_hsa041460.55171956
114Neurotrophin signaling pathway_Homo sapiens_hsa047220.54313248
115Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.53469242
116Maturity onset diabetes of the young_Homo sapiens_hsa049500.53160921
117Circadian rhythm_Homo sapiens_hsa047100.52603862
118Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52580033
119Cysteine and methionine metabolism_Homo sapiens_hsa002700.52504750
120Ether lipid metabolism_Homo sapiens_hsa005650.52406681
121Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.51668141
122Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51378713
123Huntingtons disease_Homo sapiens_hsa050160.51141702
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.49754628
125Pathways in cancer_Homo sapiens_hsa052000.49496885
126Glycerophospholipid metabolism_Homo sapiens_hsa005640.48848101
127* Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.47743703
128Homologous recombination_Homo sapiens_hsa034400.47663993
129Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.47297867
130Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.46475949
131Type II diabetes mellitus_Homo sapiens_hsa049300.45735122
132Histidine metabolism_Homo sapiens_hsa003400.45662007
133Thyroid cancer_Homo sapiens_hsa052160.45038625
134ABC transporters_Homo sapiens_hsa020100.44802357
135cGMP-PKG signaling pathway_Homo sapiens_hsa040220.44127180
136VEGF signaling pathway_Homo sapiens_hsa043700.43933349
137Adherens junction_Homo sapiens_hsa045200.43581016
138Inositol phosphate metabolism_Homo sapiens_hsa005620.42285768
139Cardiac muscle contraction_Homo sapiens_hsa042600.41491521

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