RINL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)6.08516091
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.81047354
3antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.81047354
4negative T cell selection (GO:0043383)5.38856993
5negative thymic T cell selection (GO:0045060)5.23547307
6leukocyte aggregation (GO:0070486)5.14157725
7interferon-gamma production (GO:0032609)5.11829496
8negative regulation of cell killing (GO:0031342)5.11088671
9negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.11088671
10positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)5.10956717
11antigen processing and presentation of endogenous antigen (GO:0019883)5.00320774
12positive thymic T cell selection (GO:0045059)4.91277257
13regulation of gamma-delta T cell differentiation (GO:0045586)4.78870733
14T cell migration (GO:0072678)4.70996357
15response to interleukin-15 (GO:0070672)4.44294067
16regulation of gamma-delta T cell activation (GO:0046643)4.42444984
17thymic T cell selection (GO:0045061)4.41502123
18positive T cell selection (GO:0043368)4.39113953
19regulation of B cell receptor signaling pathway (GO:0050855)4.30225440
20T cell selection (GO:0045058)4.14960420
21cellular response to interleukin-15 (GO:0071350)4.10969757
22regulation of isotype switching to IgG isotypes (GO:0048302)4.02729053
23positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.92609772
24DNA deamination (GO:0045006)3.84004999
25regulation of T cell mediated cytotoxicity (GO:0001914)3.79434339
26T cell receptor signaling pathway (GO:0050852)3.77718732
27positive regulation of T cell mediated cytotoxicity (GO:0001916)3.72262072
28activated T cell proliferation (GO:0050798)3.66702793
29Arp2/3 complex-mediated actin nucleation (GO:0034314)3.58040657
30antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.56770084
31T cell costimulation (GO:0031295)3.56761560
32lymphocyte costimulation (GO:0031294)3.51276589
33positive regulation by symbiont of host defense response (GO:0052509)3.50249654
34modulation by symbiont of host defense response (GO:0052031)3.50249654
35modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.50249654
36modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.50249654
37positive regulation by organism of defense response of other organism involved in symbiotic interact3.50249654
38modulation by symbiont of host immune response (GO:0052553)3.50249654
39regulation of antigen receptor-mediated signaling pathway (GO:0050854)3.48437388
40regulation of alpha-beta T cell proliferation (GO:0046640)3.47347725
41tolerance induction (GO:0002507)3.45727555
42antigen receptor-mediated signaling pathway (GO:0050851)3.45557032
43regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.45476878
44ribosomal small subunit assembly (GO:0000028)3.43309175
45mast cell activation (GO:0045576)3.41625155
46positive regulation of isotype switching (GO:0045830)3.39593966
47regulation of B cell differentiation (GO:0045577)3.38416448
48regulation of T cell receptor signaling pathway (GO:0050856)3.37846791
49negative regulation of phagocytosis (GO:0050765)3.33895396
50regulation of T cell tolerance induction (GO:0002664)3.31795418
51positive regulation of alpha-beta T cell proliferation (GO:0046641)3.28457890
52leukocyte cell-cell adhesion (GO:0007159)3.23774115
53negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)3.22025410
54negative regulation of adaptive immune response based on somatic recombination of immune receptors b3.21107316
55NIK/NF-kappaB signaling (GO:0038061)3.20668278
56cytidine metabolic process (GO:0046087)3.19855500
57cytidine catabolic process (GO:0006216)3.19855500
58cytidine deamination (GO:0009972)3.19855500
59positive regulation of B cell differentiation (GO:0045579)3.17527046
60regulation of response to interferon-gamma (GO:0060330)3.14636929
61regulation of natural killer cell mediated cytotoxicity (GO:0042269)3.14519302
62regulation of natural killer cell mediated immunity (GO:0002715)3.14519302
63regulation of interferon-beta biosynthetic process (GO:0045357)3.14450465
64regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.14326237
65regulation of interleukin-2 biosynthetic process (GO:0045076)3.12184952
66regulation of memory T cell differentiation (GO:0043380)3.11997939
67positive regulation of defense response to virus by host (GO:0002230)3.10382912
68regulation of interferon-gamma-mediated signaling pathway (GO:0060334)3.09697085
69defense response to protozoan (GO:0042832)3.09259814
70negative regulation of leukocyte mediated immunity (GO:0002704)3.09202596
71regulation of interleukin-12 biosynthetic process (GO:0045075)3.09180057
72antigen processing and presentation via MHC class Ib (GO:0002475)3.07177459
73sequestering of actin monomers (GO:0042989)3.04828415
74pyrimidine ribonucleoside catabolic process (GO:0046133)3.04435543
75positive regulation of cell killing (GO:0031343)3.02480736
76negative regulation of adaptive immune response (GO:0002820)3.02302308
77positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.01429942
78T cell homeostasis (GO:0043029)3.01424961
79B cell receptor signaling pathway (GO:0050853)3.01286865
80detection of bacterium (GO:0016045)3.00766045
81regulation of isotype switching (GO:0045191)2.99802857
82regulation of type I interferon-mediated signaling pathway (GO:0060338)2.98317548
83positive regulation of interleukin-17 production (GO:0032740)2.96543623
84positive regulation of interleukin-2 production (GO:0032743)2.96243108
85natural killer cell activation (GO:0030101)2.95625329
86CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.95138003
87regulation of regulatory T cell differentiation (GO:0045589)2.94713637
88negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.93600443
89negative regulation of T-helper cell differentiation (GO:0045623)2.93600443
90detection of other organism (GO:0098543)2.92325797
91positive regulation of B cell mediated immunity (GO:0002714)2.89419114
92positive regulation of immunoglobulin mediated immune response (GO:0002891)2.89419114
93negative regulation of interleukin-12 production (GO:0032695)2.88013381
94regulation of T cell mediated immunity (GO:0002709)2.87373809
95positive regulation of DNA recombination (GO:0045911)2.87106100
96positive regulation of natural killer cell mediated immunity (GO:0002717)2.84652591
97positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.84652591
98alpha-beta T cell activation (GO:0046631)2.83278552
99negative regulation of T cell mediated immunity (GO:0002710)2.83153264
100negative regulation of alpha-beta T cell activation (GO:0046636)2.82863803
101viral transcription (GO:0019083)2.82744361
102cellular extravasation (GO:0045123)2.82339365
103response to type I interferon (GO:0034340)2.81116092
104regulation of leukocyte mediated cytotoxicity (GO:0001910)2.78765287
105neutrophil activation (GO:0042119)2.77487585
106regulation of B cell mediated immunity (GO:0002712)2.76974508
107type I interferon signaling pathway (GO:0060337)2.76662617
108cellular response to type I interferon (GO:0071357)2.76662617
109regulation of immunoglobulin mediated immune response (GO:0002889)2.76366833
110T cell proliferation (GO:0042098)2.75931945
111negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.75276388
112T cell differentiation (GO:0030217)2.75129368
113positive regulation of tolerance induction (GO:0002645)2.73616192
114immunoglobulin mediated immune response (GO:0016064)2.72967750
115myeloid dendritic cell activation (GO:0001773)2.70796537
116cellular response to zinc ion (GO:0071294)2.70486678
117translational termination (GO:0006415)2.70303289
118mast cell activation involved in immune response (GO:0002279)2.70224911
119mast cell degranulation (GO:0043303)2.70224911
120neutrophil activation involved in immune response (GO:0002283)2.69400657
121interferon-gamma-mediated signaling pathway (GO:0060333)2.69353634
122regulation of alpha-beta T cell activation (GO:0046634)2.68386504
123response to protozoan (GO:0001562)2.67582342
124lymphocyte homeostasis (GO:0002260)2.67048706
125positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.66117894
126lymphocyte migration (GO:0072676)2.65983458
127adaptation of signaling pathway (GO:0023058)2.65425635
128T cell activation (GO:0042110)2.64560400
129negative regulation of lymphocyte mediated immunity (GO:0002707)2.64557504
130leukocyte degranulation (GO:0043299)2.64276124
131positive regulation of T cell mediated immunity (GO:0002711)2.62755528
132respiratory burst (GO:0045730)2.62566518
133negative regulation of T cell receptor signaling pathway (GO:0050860)2.61380263
134positive regulation of natural killer cell differentiation (GO:0032825)2.61165820
135regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.60547817
136positive regulation of granulocyte differentiation (GO:0030854)2.60168334
137cellular response to interferon-beta (GO:0035458)2.59875038
138immune response-activating cell surface receptor signaling pathway (GO:0002429)2.59801562
139regulation of cell killing (GO:0031341)2.59615721

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.81738189
2FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.30278628
3STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.90559051
4FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.73880820
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.53155920
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.18332247
7MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.03245929
8* MYC_22102868_ChIP-Seq_BL_Human2.95909190
9IRF8_21731497_ChIP-ChIP_J774_Mouse2.74546372
10EGR1_19374776_ChIP-ChIP_THP-1_Human2.73037374
11STAT4_19710469_ChIP-ChIP_TH1__Mouse2.70509880
12SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.68334443
13STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.55403491
14* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.54874980
15MYB_26560356_Chip-Seq_TH2_Human2.52586779
16EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.48100346
17VDR_21846776_ChIP-Seq_THP-1_Human2.47885449
18FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.39548663
19ZNF274_21170338_ChIP-Seq_K562_Hela2.34763545
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.32649648
21RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.32053813
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.31468134
23MAF_26560356_Chip-Seq_TH1_Human2.31203095
24ELF1_17652178_ChIP-ChIP_JURKAT_Human2.22790459
25MYB_26560356_Chip-Seq_TH1_Human2.20363885
26RUNX_20019798_ChIP-Seq_JUKART_Human2.19100176
27* SPI1_23547873_ChIP-Seq_NB4_Human2.16397168
28BP1_19119308_ChIP-ChIP_Hs578T_Human2.14204981
29UTX_26944678_Chip-Seq_JUKART_Human2.11820687
30FLI1_20887958_ChIP-Seq_HPC-7_Mouse2.05335568
31SCL_19346495_ChIP-Seq_HPC-7_Human2.04073925
32ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.00098743
33FOXM1_23109430_ChIP-Seq_U2OS_Human1.93749400
34TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.91653253
35NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.90804996
36BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.89837160
37SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.89749517
38RUNX1_22412390_ChIP-Seq_EML_Mouse1.89453939
39E2F4_17652178_ChIP-ChIP_JURKAT_Human1.87850610
40NOTCH1_21737748_ChIP-Seq_TLL_Human1.82505683
41IRF8_27001747_Chip-Seq_BMDM_Mouse1.79873294
42VDR_24763502_ChIP-Seq_THP-1_Human1.74990862
43* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.73740801
44MYC_18555785_ChIP-Seq_MESCs_Mouse1.73218893
45BRD4_27068464_Chip-Seq_AML-cells_Mouse1.73162740
46MAF_26560356_Chip-Seq_TH2_Human1.69686435
47VDR_23849224_ChIP-Seq_CD4+_Human1.67980106
48FLI1_27457419_Chip-Seq_LIVER_Mouse1.61634280
49CIITA_25753668_ChIP-Seq_RAJI_Human1.60265573
50* TCF7_22412390_ChIP-Seq_EML_Mouse1.57575708
51MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.56978171
52NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.55979976
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.55178477
54NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.55075376
55VDR_22108803_ChIP-Seq_LS180_Human1.53913699
56GABP_17652178_ChIP-ChIP_JURKAT_Human1.51037353
57FOXP3_21729870_ChIP-Seq_TREG_Human1.50982464
58E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.50592049
59VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.48229985
60GATA3_27048872_Chip-Seq_THYMUS_Human1.46641292
61EST1_17652178_ChIP-ChIP_JURKAT_Human1.45152077
62HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44776924
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.44295703
64FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.41187196
65IKZF1_21737484_ChIP-ChIP_HCT116_Human1.38499194
66NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.38101354
67GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.35769908
68HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.34549071
69GATA2_22383799_ChIP-Seq_G1ME_Mouse1.33359106
70SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.31931656
71* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.31848194
72MYC_19079543_ChIP-ChIP_MESCs_Mouse1.31214640
73KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.28435497
74XRN2_22483619_ChIP-Seq_HELA_Human1.27120181
75EGR1_23403033_ChIP-Seq_LIVER_Mouse1.26507767
76MYC_18358816_ChIP-ChIP_MESCs_Mouse1.25695838
77ETS1_20019798_ChIP-Seq_JURKAT_Human1.25638786
78JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.22991230
79GATA1_22383799_ChIP-Seq_G1ME_Mouse1.22716653
80SPI1_23127762_ChIP-Seq_K562_Human1.22409771
81LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.21904228
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.21812060
83MYC_19030024_ChIP-ChIP_MESCs_Mouse1.21104891
84FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.18179544
85TP53_22573176_ChIP-Seq_HFKS_Human1.16656166
86GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16091901
87EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.15226273
88PU_27001747_Chip-Seq_BMDM_Mouse1.12247236
89MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.11538368
90ER_23166858_ChIP-Seq_MCF-7_Human1.11468667
91KDM2B_26808549_Chip-Seq_DND41_Human1.11162216
92VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.10580447
93* SMRT_27268052_Chip-Seq_Bcells_Human1.10230502
94IRF1_19129219_ChIP-ChIP_H3396_Human1.09548459
95CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.09437802
96E2F1_21310950_ChIP-Seq_MCF-7_Human1.08592663
97PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08433533
98GATA3_26560356_Chip-Seq_TH1_Human1.07551721
99RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.06746354
100FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05818615
101FOXA1_25329375_ChIP-Seq_VCAP_Human1.05818615
102ELK1_19687146_ChIP-ChIP_HELA_Human1.05646399
103BCAT_22108803_ChIP-Seq_LS180_Human1.05487073
104CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.04980945
105TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.04300642
106TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.02811764
107RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.01594855
108P300_27268052_Chip-Seq_Bcells_Human1.01488642
109GABP_19822575_ChIP-Seq_HepG2_Human1.01384421
110* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.01147604
111NELFA_20434984_ChIP-Seq_ESCs_Mouse1.01003061
112GATA3_26560356_Chip-Seq_TH2_Human1.00269877
113VDR_24787735_ChIP-Seq_THP-1_Human1.00202371
114ELK3_25401928_ChIP-Seq_HUVEC_Human1.00162706
115GATA3_21878914_ChIP-Seq_MCF-7_Human1.00022915
116EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.99949342
117TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99528107
118PU.1_20513432_ChIP-Seq_Bcells_Mouse0.99305135
119LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.98946203
120CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.97963352
121KDM5A_27292631_Chip-Seq_BREAST_Human0.96037851
122DCP1A_22483619_ChIP-Seq_HELA_Human0.95899410
123GATA1_22025678_ChIP-Seq_K562_Human0.95840512
124TFEB_21752829_ChIP-Seq_HELA_Human0.95216495
125GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.95158697
126KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human0.95095327
127PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.94725417
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.94712097
129BCL6_27268052_Chip-Seq_Bcells_Human0.94282856
130PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.93398019
131ETV2_25802403_ChIP-Seq_MESCs_Mouse0.93178232
132CREB1_15753290_ChIP-ChIP_HEK293T_Human0.93059579
133FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.91990122
134NANOG_20526341_ChIP-Seq_ESCs_Human0.91492206
135SRF_21415370_ChIP-Seq_HL-1_Mouse0.90814116
136SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.90181293
137RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.88654599
138STAT1_20625510_ChIP-Seq_HELA_Human0.88624608
139PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.87512522
140RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.87446355
141HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.87166330
142GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.87089305
143STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.85353700
144IGF1R_20145208_ChIP-Seq_DFB_Human0.85323564
145CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.85292945
146OCT4_20526341_ChIP-Seq_ESCs_Human0.84841746
147PRDM14_20953172_ChIP-Seq_ESCs_Human0.83586382
148NCOR_22424771_ChIP-Seq_293T_Human0.83389461

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003763_abnormal_thymus_physiology4.18689271
2MP0005671_abnormal_response_to3.86982628
3MP0001835_abnormal_antigen_presentation3.58210479
4MP0000685_abnormal_immune_system3.14921222
5MP0001800_abnormal_humoral_immune2.95905525
6MP0002396_abnormal_hematopoietic_system2.88510090
7MP0009785_altered_susceptibility_to2.87303514
8MP0005000_abnormal_immune_tolerance2.79871378
9MP0003436_decreased_susceptibility_to2.79149191
10MP0002420_abnormal_adaptive_immunity2.74917907
11MP0001819_abnormal_immune_cell2.71822565
12MP0002398_abnormal_bone_marrow2.69983732
13MP0001790_abnormal_immune_system2.69584543
14MP0005387_immune_system_phenotype2.69584543
15MP0002723_abnormal_immune_serum2.68138798
16MP0009333_abnormal_splenocyte_physiolog2.62723223
17MP0005025_abnormal_response_to2.62596089
18MP0002452_abnormal_antigen_presenting2.58089051
19MP0002166_altered_tumor_susceptibility2.55294495
20MP0000716_abnormal_immune_system2.36677126
21MP0002405_respiratory_system_inflammati2.32749860
22MP0002419_abnormal_innate_immunity2.26754182
23MP0002722_abnormal_immune_system2.25204489
24MP0000703_abnormal_thymus_morphology2.23183219
25MP0001873_stomach_inflammation2.22572512
26MP0000689_abnormal_spleen_morphology2.20094626
27MP0003724_increased_susceptibility_to2.19570783
28MP0002148_abnormal_hypersensitivity_rea2.19431026
29MP0002006_tumorigenesis2.17823935
30MP0006082_CNS_inflammation2.17123061
31MP0003787_abnormal_imprinting2.11184563
32MP0003303_peritoneal_inflammation2.06415690
33MP0005464_abnormal_platelet_physiology2.04392148
34MP0002429_abnormal_blood_cell2.02725256
35MP0010155_abnormal_intestine_physiology2.02156417
36MP0000569_abnormal_digit_pigmentation1.89146172
37MP0008877_abnormal_DNA_methylation1.87859172
38MP0003866_abnormal_defecation1.80561282
39MP0004808_abnormal_hematopoietic_stem1.79741696
40MP0002138_abnormal_hepatobiliary_system1.77906633
41MP0001986_abnormal_taste_sensitivity1.77744736
42MP0002163_abnormal_gland_morphology1.74863302
43MP0005397_hematopoietic_system_phenotyp1.72635896
44MP0001545_abnormal_hematopoietic_system1.72635896
45MP0005645_abnormal_hypothalamus_physiol1.72453347
46MP0003693_abnormal_embryo_hatching1.72444201
47MP0004947_skin_inflammation1.71800550
48MP0008057_abnormal_DNA_replication1.71325953
49MP0001845_abnormal_inflammatory_respons1.70977375
50MP0000858_altered_metastatic_potential1.65339152
51MP0001853_heart_inflammation1.64320747
52MP0000490_abnormal_crypts_of1.62462960
53MP0003300_gastrointestinal_ulcer1.62221837
54MP0002277_abnormal_respiratory_mucosa1.61918324
55MP0000465_gastrointestinal_hemorrhage1.58198876
56MP0010094_abnormal_chromosome_stability1.53573639
57MP0002933_joint_inflammation1.49661660
58MP0003077_abnormal_cell_cycle1.47152482
59MP0002693_abnormal_pancreas_physiology1.46580659
60MP0003195_calcinosis1.45879380
61MP0005075_abnormal_melanosome_morpholog1.36674111
62MP0003448_altered_tumor_morphology1.33196519
63MP0005379_endocrine/exocrine_gland_phen1.32052573
64MP0010352_gastrointestinal_tract_polyps1.32002632
65MP0005310_abnormal_salivary_gland1.30905007
66MP0005084_abnormal_gallbladder_morpholo1.28970309
67MP0003111_abnormal_nucleus_morphology1.28198035
68MP0009278_abnormal_bone_marrow1.26828414
69MP0002019_abnormal_tumor_incidence1.26467679
70MP0001533_abnormal_skeleton_physiology1.26051434
71MP0004957_abnormal_blastocyst_morpholog1.25482120
72MP0008872_abnormal_physiological_respon1.23923124
73MP0008469_abnormal_protein_level1.23695679
74MP0005174_abnormal_tail_pigmentation1.22508128
75MP0004510_myositis1.18513435
76MP0002928_abnormal_bile_duct1.17593079
77MP0000372_irregular_coat_pigmentation1.16137893
78MP0010307_abnormal_tumor_latency1.14807992
79MP0008058_abnormal_DNA_repair1.12325622
80MP0002132_abnormal_respiratory_system1.10855351
81MP0003172_abnormal_lysosome_physiology1.06031226
82MP0002837_dystrophic_cardiac_calcinosis1.04561533
83MP0003011_delayed_dark_adaptation1.03458542
84MP0002009_preneoplasia1.01402894
85MP0008007_abnormal_cellular_replicative0.95922517
86MP0004142_abnormal_muscle_tone0.95663788
87MP0001851_eye_inflammation0.95115097
88MP0002254_reproductive_system_inflammat0.92990069
89MP0002876_abnormal_thyroid_physiology0.90082764
90MP0002102_abnormal_ear_morphology0.88668544
91MP0005058_abnormal_lysosome_morphology0.87861767
92MP0001968_abnormal_touch/_nociception0.87226591
93MP0001919_abnormal_reproductive_system0.86443622
94MP0005551_abnormal_eye_electrophysiolog0.86202769
95MP0003045_fibrosis0.82919076
96MP0001501_abnormal_sleep_pattern0.81453754
97MP0000313_abnormal_cell_death0.80450133
98MP0003646_muscle_fatigue0.79200433
99MP0009763_increased_sensitivity_to0.79101513
100MP0004381_abnormal_hair_follicle0.76369875
101MP0005023_abnormal_wound_healing0.75924841
102MP0000343_altered_response_to0.75524249
103MP0003252_abnormal_bile_duct0.75086071
104MP0002653_abnormal_ependyma_morphology0.74568608
105MP0004742_abnormal_vestibular_system0.71751687
106MP0000350_abnormal_cell_proliferation0.71541268
107MP0002909_abnormal_adrenal_gland0.67901548
108MP0002095_abnormal_skin_pigmentation0.67766467
109MP0009764_decreased_sensitivity_to0.67013732
110MP0000015_abnormal_ear_pigmentation0.66957060
111MP0002998_abnormal_bone_remodeling0.64653817
112MP0005076_abnormal_cell_differentiation0.64238013
113MP0001944_abnormal_pancreas_morphology0.64225954
114MP0010329_abnormal_lipoprotein_level0.63994796
115MP0000477_abnormal_intestine_morphology0.62769089
116MP0006072_abnormal_retinal_apoptosis0.61761733
117MP0003806_abnormal_nucleotide_metabolis0.61564980
118MP0002638_abnormal_pupillary_reflex0.61557504
119MP0001764_abnormal_homeostasis0.61298922
120MP0003183_abnormal_peptide_metabolism0.60921448
121MP0001765_abnormal_ion_homeostasis0.60794067
122MP0000427_abnormal_hair_cycle0.60310464
123MP0001663_abnormal_digestive_system0.60211271
124MP0009765_abnormal_xenobiotic_induced0.59821561
125MP0006035_abnormal_mitochondrial_morpho0.59482038
126MP0002078_abnormal_glucose_homeostasis0.59243289
127MP0004883_abnormal_blood_vessel0.58480687
128MP0009745_abnormal_behavioral_response0.58372348
129MP0005253_abnormal_eye_physiology0.58298886
130MP0000371_diluted_coat_color0.57390887
131MP0003786_premature_aging0.56786494
132MP0001730_embryonic_growth_arrest0.54503049
133MP0003566_abnormal_cell_adhesion0.54393234
134MP0003191_abnormal_cellular_cholesterol0.53111436
135MP0008873_increased_physiological_sensi0.50801769
136MP0003656_abnormal_erythrocyte_physiolo0.49685214
137MP0003828_pulmonary_edema0.48155401
138MP0003795_abnormal_bone_structure0.48102179
139MP0005621_abnormal_cell_physiology0.46714659
140MP0000249_abnormal_blood_vessel0.45676923
141MP0009840_abnormal_foam_cell0.44484324
142MP0000609_abnormal_liver_physiology0.44117730
143MP0002136_abnormal_kidney_physiology0.44096211
144MP0005166_decreased_susceptibility_to0.43451699

Predicted human phenotypes

RankGene SetZ-score
1T lymphocytopenia (HP:0005403)5.20009127
2Abnormality of T cell number (HP:0011839)5.01360617
3Elevated erythrocyte sedimentation rate (HP:0003565)4.91630584
4IgM deficiency (HP:0002850)4.85439728
5Eczematoid dermatitis (HP:0000976)4.84190936
6Myositis (HP:0100614)4.55776634
7Abnormality of T cells (HP:0002843)4.47570331
8Recurrent abscess formation (HP:0002722)4.43146172
9Recurrent fungal infections (HP:0002841)4.41624899
10Chronic otitis media (HP:0000389)4.40771898
11Recurrent viral infections (HP:0004429)4.23138781
12Recurrent bronchitis (HP:0002837)4.04767949
13Panhypogammaglobulinemia (HP:0003139)4.00409758
14Abnormal delayed hypersensitivity skin test (HP:0002963)3.93382650
15Severe combined immunodeficiency (HP:0004430)3.89589037
16Nasal polyposis (HP:0100582)3.89111099
17Stomatitis (HP:0010280)3.84445644
18Combined immunodeficiency (HP:0005387)3.75995525
19Thrombocytosis (HP:0001894)3.65956577
20Pustule (HP:0200039)3.62917175
21Abnormality of T cell physiology (HP:0011840)3.62600609
22Recurrent bacterial skin infections (HP:0005406)3.55800851
23Recurrent cutaneous fungal infections (HP:0011370)3.55071059
24Chronic mucocutaneous candidiasis (HP:0002728)3.55071059
25Obstructive lung disease (HP:0006536)3.49681009
26Chronic obstructive pulmonary disease (HP:0006510)3.49681009
27Meningitis (HP:0001287)3.48531434
28IgG deficiency (HP:0004315)3.38291835
29Abnormality of the nasal mucosa (HP:0000433)3.36929222
30Eosinophilia (HP:0001880)3.31204855
31Abnormality of eosinophils (HP:0001879)3.26107313
32Mediastinal lymphadenopathy (HP:0100721)3.18404722
33Optic neuritis (HP:0100653)3.17606650
34Retrobulbar optic neuritis (HP:0100654)3.17606650
35Abnormality of B cell number (HP:0010975)3.16695367
36B lymphocytopenia (HP:0010976)3.16695367
37Granulocytopenia (HP:0001913)3.15898842
38Leukocytosis (HP:0001974)3.10268971
39Lymphopenia (HP:0001888)3.05901540
40Recurrent skin infections (HP:0001581)3.04012299
41Orchitis (HP:0100796)3.03537891
42Thyroiditis (HP:0100646)3.00761350
43Abnormality of cells of the lymphoid lineage (HP:0012140)2.99993521
44Abnormality of the fingertips (HP:0001211)2.97203289
45Spontaneous hematomas (HP:0007420)2.96736556
46Autoimmune thrombocytopenia (HP:0001973)2.95325063
47Vasculitis (HP:0002633)2.95298570
48Encephalitis (HP:0002383)2.92773909
49Congenital stationary night blindness (HP:0007642)2.90522222
50Inflammation of the large intestine (HP:0002037)2.89865986
51Abnormality of macrophages (HP:0004311)2.88350570
52Petechiae (HP:0000967)2.85648643
53Stomach cancer (HP:0012126)2.85399192
54Gastrointestinal inflammation (HP:0004386)2.81955442
55Autoimmune hemolytic anemia (HP:0001890)2.81866731
56Hemoptysis (HP:0002105)2.75979604
57Lymphoma (HP:0002665)2.74982158
58Increased IgE level (HP:0003212)2.65441457
59Hypochromic anemia (HP:0001931)2.65415113
60Prolonged bleeding time (HP:0003010)2.64545725
61Chronic diarrhea (HP:0002028)2.59254011
62Pancreatic cysts (HP:0001737)2.59113418
63Basal cell carcinoma (HP:0002671)2.53579489
64Pulmonary infiltrates (HP:0002113)2.52887973
65Epistaxis (HP:0000421)2.50648894
66Recurrent gram-negative bacterial infections (HP:0005420)2.50340096
67Hypergammaglobulinemia (HP:0010702)2.49134973
68IgA deficiency (HP:0002720)2.42545709
69Gastrointestinal infarctions (HP:0005244)2.41658212
70Joint swelling (HP:0001386)2.40535237
71Chest pain (HP:0100749)2.38861779
72Abnormal rod and cone electroretinograms (HP:0008323)2.36112486
73Abnormality of cells of the erythroid lineage (HP:0012130)2.31549133
74Keratoconjunctivitis sicca (HP:0001097)2.31124890
75Recurrent sinusitis (HP:0011108)2.30899791
76Cellulitis (HP:0100658)2.30462332
77Arterial thrombosis (HP:0004420)2.29489995
78Abnormal number of erythroid precursors (HP:0012131)2.28989597
79Agammaglobulinemia (HP:0004432)2.27168371
80Reticulocytopenia (HP:0001896)2.26003515
81Increased IgM level (HP:0003496)2.25861120
82Abnormality of the prostate (HP:0008775)2.24864196
83Periodontitis (HP:0000704)2.23257670
84Bronchitis (HP:0012387)2.22116169
85Gastrointestinal stroma tumor (HP:0100723)2.22114557
86Pancreatic fibrosis (HP:0100732)2.19004937
87Poikiloderma (HP:0001029)2.18736512
88Attenuation of retinal blood vessels (HP:0007843)2.18412131
89Amaurosis fugax (HP:0100576)2.17374171
90Hypochromic microcytic anemia (HP:0004840)2.16559786
91Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16436382
92Episodic fever (HP:0001954)2.12598301
93Abnormality of the renal cortex (HP:0011035)2.11379577
94Gingivitis (HP:0000230)2.10880617
95Verrucae (HP:0200043)2.09179497
96Papilloma (HP:0012740)2.09179497
97Chronic sinusitis (HP:0011109)2.08703072
98Hypoplasia of the thymus (HP:0000778)2.08652981
99Keratoconjunctivitis (HP:0001096)2.07728681
100Skin ulcer (HP:0200042)2.07542664
101Anorexia (HP:0002039)2.07297984
102Interstitial pulmonary disease (HP:0006530)2.04973239
103Colitis (HP:0002583)2.04565159
104Urticaria (HP:0001025)2.03271208
105Gingival bleeding (HP:0000225)2.01497925
106Aplastic anemia (HP:0001915)2.01293372
107Pulmonary embolism (HP:0002204)2.00493693
108Abnormality of the pleura (HP:0002103)1.99500336
109Abnormal platelet volume (HP:0011876)1.98351426
110Keratitis (HP:0000491)1.98161308
111Cheilitis (HP:0100825)1.96211140
112Neutropenia (HP:0001875)1.92867090
113Gangrene (HP:0100758)1.92635660
114Acute hepatic failure (HP:0006554)1.92523231
115Impaired platelet aggregation (HP:0003540)1.92486700
116Abnormal platelet function (HP:0011869)1.92486700
117Aplasia/Hypoplasia of the thymus (HP:0010515)1.91174459
118Abnormality of midbrain morphology (HP:0002418)1.89121568
119Molar tooth sign on MRI (HP:0002419)1.89121568
120Entropion (HP:0000621)1.88649807
121Asplenia (HP:0001746)1.84609078
122True hermaphroditism (HP:0010459)1.82467633
123Aplasia/Hypoplasia of the spleen (HP:0010451)1.82396953
124Nephronophthisis (HP:0000090)1.79046116
125Hematochezia (HP:0002573)1.78527383
126Constricted visual fields (HP:0001133)1.77995424
127Ketoacidosis (HP:0001993)1.75737241
128Progressive inability to walk (HP:0002505)1.75445399
1293-Methylglutaconic aciduria (HP:0003535)1.75151219
130Ketosis (HP:0001946)1.72736931

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K15.48021983
2TXK4.85521874
3FRK3.90335752
4JAK32.89014840
5ZAP702.86033609
6ITK2.53568028
7TYK22.49464361
8STK102.45119218
9IKBKE2.41204556
10MAP4K22.11962855
11BLK2.10564766
12GRK62.09605594
13IRAK42.08892218
14TEC1.99027701
15NME21.96146988
16BTK1.87551586
17TBK11.81019887
18MAP3K141.80035123
19EEF2K1.76676680
20LCK1.76236000
21FGFR41.75677610
22JAK11.67137724
23KDR1.64680318
24KIT1.64670113
25SYK1.57314233
26CSK1.55556785
27TESK21.45762636
28ZAK1.41398449
29PIM11.37999924
30HCK1.37546449
31FES1.35645576
32RPS6KA41.33058187
33GRK11.30800224
34FGFR31.29580734
35CLK11.28689465
36NLK1.26278675
37MAP3K101.25038395
38PKN21.24236501
39WNK41.21796379
40IKBKB1.18541137
41CSF1R1.17751406
42FLT31.14287983
43LRRK21.12369843
44MAPK131.11301385
45CAMKK21.10659977
46IRAK11.09739495
47INSRR1.09434689
48IRAK31.09309857
49NUAK11.05975149
50NEK21.03626502
51CDK41.02448884
52TAOK30.99203267
53EPHB10.99001403
54MAP3K130.98395706
55LYN0.98245813
56MST40.97241684
57MAP2K30.96531411
58MARK30.96102424
59OXSR10.94241973
60PIM20.92785844
61DAPK20.91397448
62WNK30.89697603
63JAK20.85159979
64CDC70.84893749
65STK390.81817577
66PRKCQ0.81175351
67STK40.78992551
68CDK120.76768770
69BMPR1B0.76594479
70PAK30.74693436
71PINK10.73192920
72PASK0.69877545
73TNK20.69588223
74PTK2B0.67755879
75STK110.67268273
76SIK20.66479993
77WEE10.66394704
78RPS6KB20.66298043
79MAP3K80.64690908
80CHUK0.64359626
81CAMKK10.63673604
82TSSK60.63517100
83TGFBR20.63213486
84MAP3K120.63202053
85ATR0.63177447
86YES10.62700917
87BUB10.62492052
88PIK3CG0.61258865
89FGR0.59509591
90ALK0.59297038
91MUSK0.58483320
92VRK10.56453210
93RAF10.54574574
94CDK70.53700447
95EIF2AK10.52364692
96PRKCH0.51557677
97MATK0.50903878
98TGFBR10.50155232
99TRIB30.50108562
100NTRK30.49247080
101BMPR20.48708868
102ACVR1B0.48583856
103FGFR20.48377060
104TRPM70.48303605
105BCKDK0.47543941
106PRKD20.46992581
107MAP2K20.45407516
108PRKCZ0.43753208
109BRD40.43475679
110ADRBK10.42439529
111RPS6KA60.42144061
112MAP3K40.41005421
113ADRBK20.40909853
114PAK40.40491405
115EIF2AK30.40234440
116MAPK110.39951135
117MAPK120.39845068
118MAP3K10.39271979
119SCYL20.39159506
120PDK10.37915773
121SRPK10.37229135
122STK240.36878859
123ERN10.36711607
124TNIK0.36261011
125TTN0.36070136
126STK160.34692372
127TLK10.34142603
128RPS6KA50.32656866
129MAPK40.32634361
130RPS6KC10.31723967
131RPS6KL10.31723967
132TAOK10.31099232
133MAPKAPK20.30582114
134MAP3K110.30579185
135MAPK70.30561133
136HIPK20.28670521
137SIK30.28003975
138MAP2K60.27776858
139RIPK40.27601834
140ABL10.27153174
141NME10.25632185
142DYRK20.25203311
143PRKCI0.24767255
144PDPK10.24387776
145MAP3K70.23977165

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.20135544
2Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.66339556
3T cell receptor signaling pathway_Homo sapiens_hsa046602.60118837
4Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.59974149
5Antigen processing and presentation_Homo sapiens_hsa046122.55479946
6Graft-versus-host disease_Homo sapiens_hsa053322.50305456
7DNA replication_Homo sapiens_hsa030302.48085610
8Measles_Homo sapiens_hsa051622.46212450
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.30939710
10Allograft rejection_Homo sapiens_hsa053302.20021413
11Leishmaniasis_Homo sapiens_hsa051402.19893324
12NF-kappa B signaling pathway_Homo sapiens_hsa040642.19433273
13Ribosome_Homo sapiens_hsa030102.03447625
14Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.00334847
15Hematopoietic cell lineage_Homo sapiens_hsa046401.87172933
16Mismatch repair_Homo sapiens_hsa034301.82888953
17Osteoclast differentiation_Homo sapiens_hsa043801.76949659
18Maturity onset diabetes of the young_Homo sapiens_hsa049501.75989511
19B cell receptor signaling pathway_Homo sapiens_hsa046621.75166051
20alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.74370716
21Herpes simplex infection_Homo sapiens_hsa051681.70937159
22RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.64941903
23Base excision repair_Homo sapiens_hsa034101.61930099
24Jak-STAT signaling pathway_Homo sapiens_hsa046301.58137144
25Autoimmune thyroid disease_Homo sapiens_hsa053201.48520060
26Linoleic acid metabolism_Homo sapiens_hsa005911.48378378
27Viral myocarditis_Homo sapiens_hsa054161.45962740
28Spliceosome_Homo sapiens_hsa030401.45852773
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.41846397
30NOD-like receptor signaling pathway_Homo sapiens_hsa046211.31910627
31Phototransduction_Homo sapiens_hsa047441.29455026
32Leukocyte transendothelial migration_Homo sapiens_hsa046701.26389929
33Shigellosis_Homo sapiens_hsa051311.26130765
34Homologous recombination_Homo sapiens_hsa034401.24081382
35Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.23647402
36Non-homologous end-joining_Homo sapiens_hsa034501.22910526
37Hepatitis B_Homo sapiens_hsa051611.22675967
38Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.22651035
39Legionellosis_Homo sapiens_hsa051341.21834603
40Acute myeloid leukemia_Homo sapiens_hsa052211.21495856
41Toll-like receptor signaling pathway_Homo sapiens_hsa046201.21341807
42Nucleotide excision repair_Homo sapiens_hsa034201.20603884
43Apoptosis_Homo sapiens_hsa042101.20022980
44Influenza A_Homo sapiens_hsa051641.19878452
45Toxoplasmosis_Homo sapiens_hsa051451.18274228
46Ether lipid metabolism_Homo sapiens_hsa005651.17372423
47Asthma_Homo sapiens_hsa053101.16431002
48Chemokine signaling pathway_Homo sapiens_hsa040621.14204716
49Epstein-Barr virus infection_Homo sapiens_hsa051691.11294262
50Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.05988021
51Proteasome_Homo sapiens_hsa030501.01804120
52Staphylococcus aureus infection_Homo sapiens_hsa051501.00313137
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.99517317
54Other glycan degradation_Homo sapiens_hsa005110.98597867
55p53 signaling pathway_Homo sapiens_hsa041150.96769228
56Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.96494197
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.94074248
58TNF signaling pathway_Homo sapiens_hsa046680.93476223
59Cell cycle_Homo sapiens_hsa041100.93241573
60Malaria_Homo sapiens_hsa051440.93114039
61Regulation of autophagy_Homo sapiens_hsa041400.92398368
62Tuberculosis_Homo sapiens_hsa051520.92328831
63HTLV-I infection_Homo sapiens_hsa051660.92169836
64Viral carcinogenesis_Homo sapiens_hsa052030.91832025
65RNA polymerase_Homo sapiens_hsa030200.90377741
66Pertussis_Homo sapiens_hsa051330.90327135
67RNA transport_Homo sapiens_hsa030130.89649885
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.88859363
69Type I diabetes mellitus_Homo sapiens_hsa049400.86616530
70Chronic myeloid leukemia_Homo sapiens_hsa052200.84601200
71Pyrimidine metabolism_Homo sapiens_hsa002400.84446710
72Platelet activation_Homo sapiens_hsa046110.83720894
73RNA degradation_Homo sapiens_hsa030180.83665015
74Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.83207741
75Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.83197580
76Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82770640
77Nitrogen metabolism_Homo sapiens_hsa009100.82684202
78SNARE interactions in vesicular transport_Homo sapiens_hsa041300.81771228
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81498432
80Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80685547
81ABC transporters_Homo sapiens_hsa020100.80244325
82Butanoate metabolism_Homo sapiens_hsa006500.80071614
83African trypanosomiasis_Homo sapiens_hsa051430.79221330
84Pancreatic cancer_Homo sapiens_hsa052120.79120032
85Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.77010144
86Fanconi anemia pathway_Homo sapiens_hsa034600.75733148
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.72595312
88Hepatitis C_Homo sapiens_hsa051600.72464261
89Pentose phosphate pathway_Homo sapiens_hsa000300.71217309
90Salmonella infection_Homo sapiens_hsa051320.70999546
91One carbon pool by folate_Homo sapiens_hsa006700.69946627
92Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69740806
93Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.65574144
94Colorectal cancer_Homo sapiens_hsa052100.64989292
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.63939002
96Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63671322
97Dorso-ventral axis formation_Homo sapiens_hsa043200.59908252
98Non-small cell lung cancer_Homo sapiens_hsa052230.59128371
99VEGF signaling pathway_Homo sapiens_hsa043700.57419099
100Selenocompound metabolism_Homo sapiens_hsa004500.57124862
101Basal transcription factors_Homo sapiens_hsa030220.56423842
102Collecting duct acid secretion_Homo sapiens_hsa049660.55818333
103Small cell lung cancer_Homo sapiens_hsa052220.55105858
104Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.55058332
105Oxidative phosphorylation_Homo sapiens_hsa001900.54671935
106Neurotrophin signaling pathway_Homo sapiens_hsa047220.54350440
107Carbohydrate digestion and absorption_Homo sapiens_hsa049730.53441095
108Arachidonic acid metabolism_Homo sapiens_hsa005900.52220964
109Prolactin signaling pathway_Homo sapiens_hsa049170.51646362
110mRNA surveillance pathway_Homo sapiens_hsa030150.50731750
111AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.50672533
112Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.49717096
113Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.49313733
114Protein export_Homo sapiens_hsa030600.48516296
115Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.48384106
116Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44184382
117Glycerolipid metabolism_Homo sapiens_hsa005610.41555620
118Thyroid cancer_Homo sapiens_hsa052160.40354341
119Glycosaminoglycan degradation_Homo sapiens_hsa005310.40090560
120Phagosome_Homo sapiens_hsa041450.40084606
121Rheumatoid arthritis_Homo sapiens_hsa053230.39546491
122Lysosome_Homo sapiens_hsa041420.38924457
123Systemic lupus erythematosus_Homo sapiens_hsa053220.38329581
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.36795006
125Regulation of actin cytoskeleton_Homo sapiens_hsa048100.36463885
126Notch signaling pathway_Homo sapiens_hsa043300.32237617
127Type II diabetes mellitus_Homo sapiens_hsa049300.32025643
128Peroxisome_Homo sapiens_hsa041460.31991001
129Endocytosis_Homo sapiens_hsa041440.31774686
130Parkinsons disease_Homo sapiens_hsa050120.31613925
131Phosphatidylinositol signaling system_Homo sapiens_hsa040700.29907789
132HIF-1 signaling pathway_Homo sapiens_hsa040660.29747161
133N-Glycan biosynthesis_Homo sapiens_hsa005100.29376236
134Caffeine metabolism_Homo sapiens_hsa002320.29213434
135Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.27960144
136MAPK signaling pathway_Homo sapiens_hsa040100.25871477
137Inositol phosphate metabolism_Homo sapiens_hsa005620.25442007
138Sphingolipid signaling pathway_Homo sapiens_hsa040710.25245552
139Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.25222658
140Olfactory transduction_Homo sapiens_hsa047400.24911590
141Morphine addiction_Homo sapiens_hsa050320.24774159
142FoxO signaling pathway_Homo sapiens_hsa040680.24413378

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