RMDN1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of mitochondrial translation (GO:0070129)4.08010031
2regulation of relaxation of muscle (GO:1901077)3.95740876
3proteasome assembly (GO:0043248)3.95584329
4establishment of protein localization to mitochondrial membrane (GO:0090151)3.92693178
5erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.91822114
6L-phenylalanine catabolic process (GO:0006559)3.91822114
7negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)3.91183438
8mitochondrial respiratory chain complex assembly (GO:0033108)3.87356190
9mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.86154889
10positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)3.86129982
11central nervous system myelination (GO:0022010)3.81841263
12axon ensheathment in central nervous system (GO:0032291)3.81841263
13succinate metabolic process (GO:0006105)3.77836973
14negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 3.75115727
15regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)3.72692840
16aromatic amino acid family catabolic process (GO:0009074)3.66796570
17fatty acid elongation (GO:0030497)3.66645647
18regulation of skeletal muscle contraction (GO:0014819)3.63005384
19oxidative phosphorylation (GO:0006119)3.59243934
20actin-myosin filament sliding (GO:0033275)3.54197534
21muscle filament sliding (GO:0030049)3.54197534
22regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.53828434
23tryptophan catabolic process (GO:0006569)3.51642580
24indole-containing compound catabolic process (GO:0042436)3.51642580
25indolalkylamine catabolic process (GO:0046218)3.51642580
26erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.51084483
27L-phenylalanine metabolic process (GO:0006558)3.51084483
28regulation of cell communication by electrical coupling (GO:0010649)3.48224991
29regulation of cilium movement (GO:0003352)3.47575868
30maturation of 5.8S rRNA (GO:0000460)3.47407369
31regulation of acyl-CoA biosynthetic process (GO:0050812)3.45914296
32nucleotide transmembrane transport (GO:1901679)3.37604784
33negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.35463698
34positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517)3.33740682
35tryptophan metabolic process (GO:0006568)3.30526009
36cellular ketone body metabolic process (GO:0046950)3.25434598
37tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.24856888
38RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.24856888
39protein neddylation (GO:0045116)3.23355038
40actin-mediated cell contraction (GO:0070252)3.18285558
41inner mitochondrial membrane organization (GO:0007007)3.17387464
42amine catabolic process (GO:0009310)3.16638295
43cellular biogenic amine catabolic process (GO:0042402)3.16638295
44opsonization (GO:0008228)3.14422385
45cullin deneddylation (GO:0010388)3.13535742
46respiratory electron transport chain (GO:0022904)3.12760377
47biotin metabolic process (GO:0006768)3.11003462
48positive regulation of cellular amine metabolic process (GO:0033240)3.10608192
49tricarboxylic acid cycle (GO:0006099)3.07903387
50regulation of coenzyme metabolic process (GO:0051196)3.07161003
51regulation of cofactor metabolic process (GO:0051193)3.07161003
52otic vesicle formation (GO:0030916)3.03807686
53electron transport chain (GO:0022900)3.03360022
54regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)3.02584411
55NAD biosynthetic process (GO:0009435)3.01339620
56valine metabolic process (GO:0006573)3.01021675
57attachment of spindle microtubules to kinetochore (GO:0008608)3.00049564
58organelle disassembly (GO:1903008)2.98544057
59GPI anchor biosynthetic process (GO:0006506)2.96437427
60regulation of sulfur metabolic process (GO:0042762)2.95405121
61regulation of cholesterol esterification (GO:0010872)2.91833250
62ribonucleoprotein complex disassembly (GO:0032988)2.91420945
63GPI anchor metabolic process (GO:0006505)2.90717734
64regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.88789468
65bile acid biosynthetic process (GO:0006699)2.85799775
66uronic acid metabolic process (GO:0006063)2.85148265
67glucuronate metabolic process (GO:0019585)2.85148265
68negative regulation of signal transduction by p53 class mediator (GO:1901797)2.84565987
69short-chain fatty acid metabolic process (GO:0046459)2.84460663
70adenosine metabolic process (GO:0046085)2.84211979
71aldehyde catabolic process (GO:0046185)2.84079192
72regulation of triglyceride catabolic process (GO:0010896)2.83309863
73anterograde synaptic vesicle transport (GO:0048490)2.81251212
74negative regulation of lipase activity (GO:0060192)2.80810198
75regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.80344784
76ketone body metabolic process (GO:1902224)2.79355253
77pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.79330387
78presynaptic membrane assembly (GO:0097105)2.78577180
79triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.77300384
80lipid particle organization (GO:0034389)2.76367117
81branched-chain amino acid catabolic process (GO:0009083)2.76210526
82mannosylation (GO:0097502)2.75166009
83CENP-A containing nucleosome assembly (GO:0034080)2.73737740
84cellular glucuronidation (GO:0052695)2.73141497
85kynurenine metabolic process (GO:0070189)2.72763177
86glyoxylate metabolic process (GO:0046487)2.71339605
87indolalkylamine metabolic process (GO:0006586)2.70174583
88chromatin remodeling at centromere (GO:0031055)2.65291340
89carnitine metabolic process (GO:0009437)2.64700635
90limb bud formation (GO:0060174)2.64274740
91replication fork processing (GO:0031297)2.63432562
92pseudouridine synthesis (GO:0001522)2.62986613
93aromatic amino acid family metabolic process (GO:0009072)2.62939799
94protein deneddylation (GO:0000338)2.62015533
95respiratory chain complex IV assembly (GO:0008535)2.60949680
96polyol catabolic process (GO:0046174)2.60719596
97signal peptide processing (GO:0006465)2.60363308
98coenzyme catabolic process (GO:0009109)2.60024558
99xenobiotic catabolic process (GO:0042178)2.58572241
100long-chain fatty acid biosynthetic process (GO:0042759)2.58063770
101mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.57992515
102mitochondrial respiratory chain complex I assembly (GO:0032981)2.57992515
103NADH dehydrogenase complex assembly (GO:0010257)2.57992515
104ATP synthesis coupled proton transport (GO:0015986)2.57447170
105energy coupled proton transport, down electrochemical gradient (GO:0015985)2.57447170
106fatty acid transmembrane transport (GO:1902001)2.56950567
107phospholipid efflux (GO:0033700)2.56709503
108protein complex biogenesis (GO:0070271)2.56395277
109histone mRNA metabolic process (GO:0008334)2.54996601
110regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.53830679
111regulation of mitotic spindle checkpoint (GO:1903504)2.53830679
112regulation of pigment cell differentiation (GO:0050932)2.53356371
113very long-chain fatty acid metabolic process (GO:0000038)2.52021857
114presynaptic membrane organization (GO:0097090)2.50102095
115intracellular protein transmembrane import (GO:0044743)2.49810523
116ubiquinone biosynthetic process (GO:0006744)2.49556811
117quinone biosynthetic process (GO:1901663)2.49556811
118C-terminal protein lipidation (GO:0006501)2.49384948
119polyol transport (GO:0015791)2.48888425
120tyrosine metabolic process (GO:0006570)2.47990997
121nucleoside diphosphate catabolic process (GO:0009134)2.47335863
122cellular respiration (GO:0045333)2.46588863
123sarcomere organization (GO:0045214)2.45897369
124response to nitrosative stress (GO:0051409)2.45571800
125mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.45469143
126regulation of activation of Janus kinase activity (GO:0010533)2.45297811
127cofactor catabolic process (GO:0051187)2.45239743
128positive regulation of developmental pigmentation (GO:0048087)2.45088707
129glycogen biosynthetic process (GO:0005978)2.44648219
130glucan biosynthetic process (GO:0009250)2.44648219
131blood coagulation, intrinsic pathway (GO:0007597)2.44310302
132regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.44080064
133pyridine nucleotide biosynthetic process (GO:0019363)2.43486117
134nicotinamide nucleotide biosynthetic process (GO:0019359)2.43486117
135recombinational repair (GO:0000725)2.43218803
136C-terminal protein amino acid modification (GO:0018410)2.43084731
137epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.43046314
138low-density lipoprotein particle remodeling (GO:0034374)2.42651663
139ubiquinone metabolic process (GO:0006743)2.41931488
140nucleotide transport (GO:0006862)2.40648191
141high-density lipoprotein particle remodeling (GO:0034375)2.39400810
142fatty acid beta-oxidation (GO:0006635)2.39260203
143lipid oxidation (GO:0034440)2.39244480
144fatty acid oxidation (GO:0019395)2.39166843
145fatty acid catabolic process (GO:0009062)2.39158393
146cytochrome complex assembly (GO:0017004)2.38042171
147bile acid metabolic process (GO:0008206)2.36942192
148regulation of fibrinolysis (GO:0051917)2.35535676
149preassembly of GPI anchor in ER membrane (GO:0016254)2.34481669
150regulation of sequestering of triglyceride (GO:0010889)2.33775519
151isoprenoid biosynthetic process (GO:0008299)2.31559834
152fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.30108451
153monocarboxylic acid catabolic process (GO:0072329)2.29169085
154cholesterol efflux (GO:0033344)2.27289114
155daunorubicin metabolic process (GO:0044597)2.27104958
156polyketide metabolic process (GO:0030638)2.27104958
157doxorubicin metabolic process (GO:0044598)2.27104958
158cholesterol biosynthetic process (GO:0006695)2.26954838
159positive regulation of action potential (GO:0045760)2.26331420
160branched-chain amino acid metabolic process (GO:0009081)2.25510810
161eye photoreceptor cell differentiation (GO:0001754)2.23696268
162photoreceptor cell differentiation (GO:0046530)2.23696268
163amino-acid betaine metabolic process (GO:0006577)2.23422772
164response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.23120251
165omega-hydroxylase P450 pathway (GO:0097267)2.22743886
166quinone metabolic process (GO:1901661)2.22184335
167positive regulation of protein homodimerization activity (GO:0090073)2.22142623
168plasma lipoprotein particle remodeling (GO:0034369)2.21886825
169protein-lipid complex remodeling (GO:0034368)2.21886825
170macromolecular complex remodeling (GO:0034367)2.21886825

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.33243382
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.15671490
3EGR1_23403033_ChIP-Seq_LIVER_Mouse2.91197510
4SALL1_21062744_ChIP-ChIP_HESCs_Human2.73521645
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.58177727
6ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.50738988
7ZFP57_27257070_Chip-Seq_ESCs_Mouse2.39734213
8TAF15_26573619_Chip-Seq_HEK293_Human2.36496206
9ELK1_19687146_ChIP-ChIP_HELA_Human2.31233372
10EWS_26573619_Chip-Seq_HEK293_Human2.27745670
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.25085035
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.19315421
13BP1_19119308_ChIP-ChIP_Hs578T_Human2.15690061
14POU3F2_20337985_ChIP-ChIP_501MEL_Human2.14323741
15RBPJ_22232070_ChIP-Seq_NCS_Mouse2.13712271
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.11894387
17TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.09219441
18VDR_22108803_ChIP-Seq_LS180_Human1.96110792
19ZNF274_21170338_ChIP-Seq_K562_Hela1.93320722
20PCGF2_27294783_Chip-Seq_ESCs_Mouse1.90948657
21FLI1_27457419_Chip-Seq_LIVER_Mouse1.87313895
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.85311001
23PADI4_21655091_ChIP-ChIP_MCF-7_Human1.80305622
24BMI1_23680149_ChIP-Seq_NPCS_Mouse1.79137373
25EZH2_22144423_ChIP-Seq_EOC_Human1.78353396
26RXR_22158963_ChIP-Seq_LIVER_Mouse1.77606951
27P300_19829295_ChIP-Seq_ESCs_Human1.71283409
28SUZ12_27294783_Chip-Seq_NPCs_Mouse1.69941925
29GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.69357598
30CBX2_27304074_Chip-Seq_ESCs_Mouse1.64022048
31EED_16625203_ChIP-ChIP_MESCs_Mouse1.61895520
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.60165912
33SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.59402357
34CDX2_19796622_ChIP-Seq_MESCs_Mouse1.57776335
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.56991629
36EZH2_27294783_Chip-Seq_NPCs_Mouse1.56221376
37NFE2_27457419_Chip-Seq_LIVER_Mouse1.56020985
38SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.55473503
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.55367585
40IGF1R_20145208_ChIP-Seq_DFB_Human1.54885845
41CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.54029990
42VDR_23849224_ChIP-Seq_CD4+_Human1.53912272
43PCGF2_27294783_Chip-Seq_NPCs_Mouse1.53731419
44E2F4_17652178_ChIP-ChIP_JURKAT_Human1.52465181
45EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.52395117
46SRF_21415370_ChIP-Seq_HL-1_Mouse1.52365006
47AR_21572438_ChIP-Seq_LNCaP_Human1.52291315
48SUZ12_18555785_Chip-Seq_ESCs_Mouse1.51858492
49PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.50698320
50LXR_22158963_ChIP-Seq_LIVER_Mouse1.50459877
51RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48629239
52SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.48461669
53JARID2_20064375_ChIP-Seq_MESCs_Mouse1.48015016
54ER_23166858_ChIP-Seq_MCF-7_Human1.46285302
55CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45589757
56STAT3_18555785_Chip-Seq_ESCs_Mouse1.45116633
57EZH2_27304074_Chip-Seq_ESCs_Mouse1.44485210
58P53_22387025_ChIP-Seq_ESCs_Mouse1.44098357
59FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.43984509
60EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.43630890
61FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.43451548
62RUNX1_27457419_Chip-Seq_LIVER_Mouse1.42487146
63TP53_16413492_ChIP-PET_HCT116_Human1.42457571
64NANOG_18555785_Chip-Seq_ESCs_Mouse1.42360299
65SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.40636346
66CBP_20019798_ChIP-Seq_JUKART_Human1.39859650
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.39859650
68FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.39581703
69JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.39343299
70SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38614015
71MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.37876971
72P300_18555785_Chip-Seq_ESCs_Mouse1.37625157
73SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.37557763
74E2F1_18555785_Chip-Seq_ESCs_Mouse1.37096483
75MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.37048346
76TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.36371878
77CTBP1_25329375_ChIP-Seq_LNCAP_Human1.35152050
78FOXM1_26456572_ChIP-Seq_MCF-7_Human1.35135160
79CREB1_15753290_ChIP-ChIP_HEK293T_Human1.35113865
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.34716836
81SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.34262462
82EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33400292
83TAL1_26923725_Chip-Seq_HPCs_Mouse1.32668124
84RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.32142481
85NMYC_18555785_Chip-Seq_ESCs_Mouse1.30856057
86HTT_18923047_ChIP-ChIP_STHdh_Human1.30239771
87SOX2_19829295_ChIP-Seq_ESCs_Human1.29844357
88NANOG_19829295_ChIP-Seq_ESCs_Human1.29844357
89CMYC_18555785_Chip-Seq_ESCs_Mouse1.29174490
90IRF1_19129219_ChIP-ChIP_H3396_Human1.28207813
91FUS_26573619_Chip-Seq_HEK293_Human1.27407882
92PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26871628
93BCAT_22108803_ChIP-Seq_LS180_Human1.26251450
94EZH2_27294783_Chip-Seq_ESCs_Mouse1.26222100
95CRX_20693478_ChIP-Seq_RETINA_Mouse1.26149859
96OCT4_18555785_Chip-Seq_ESCs_Mouse1.25729338
97ETS1_20019798_ChIP-Seq_JURKAT_Human1.24440865
98SMAD1_18555785_Chip-Seq_ESCs_Mouse1.24191664
99SMAD3_21741376_ChIP-Seq_EPCs_Human1.23921283
100CTBP2_25329375_ChIP-Seq_LNCAP_Human1.23795327
101SOX2_18555785_Chip-Seq_ESCs_Mouse1.23298647
102FOXP3_21729870_ChIP-Seq_TREG_Human1.21285267
103PU1_27457419_Chip-Seq_LIVER_Mouse1.20907751
104JARID2_20075857_ChIP-Seq_MESCs_Mouse1.20479211
105PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.20471945
106MYC_18940864_ChIP-ChIP_HL60_Human1.20151963
107NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.18590291
108NRF2_20460467_ChIP-Seq_MEFs_Mouse1.18590291
109TCF4_22108803_ChIP-Seq_LS180_Human1.18269520
110EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.18007593
111LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.17479166
112ZFX_18555785_Chip-Seq_ESCs_Mouse1.17403664
113STAT3_23295773_ChIP-Seq_U87_Human1.16968222
114RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.15829026
115KLF5_20875108_ChIP-Seq_MESCs_Mouse1.15696398
116PPARA_22158963_ChIP-Seq_LIVER_Mouse1.15483776
117OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15011839
118KLF4_18555785_Chip-Seq_ESCs_Mouse1.14782304
119SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.14671687
120MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14506033
121NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13277026
122CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.13269648
123ESRRB_18555785_Chip-Seq_ESCs_Mouse1.13254605
124RNF2_18974828_ChIP-Seq_MESCs_Mouse1.13201218
125EZH2_18974828_ChIP-Seq_MESCs_Mouse1.13201218
126CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12875538
127SMAD4_21799915_ChIP-Seq_A2780_Human1.12559250
128SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.11853497
129TOP2B_26459242_ChIP-Seq_MCF-7_Human1.11803514
130CTCF_18555785_Chip-Seq_ESCs_Mouse1.11218655
131TP53_18474530_ChIP-ChIP_U2OS_Human1.10064942
132CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.09936512
133OCT4_21477851_ChIP-Seq_ESCs_Mouse1.09932478
134MTF2_20144788_ChIP-Seq_MESCs_Mouse1.08672248
135SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.08422270
136AR_20517297_ChIP-Seq_VCAP_Human1.08199506
137TCF4_23295773_ChIP-Seq_U87_Human1.08106368
138RNF2_27304074_Chip-Seq_NSC_Mouse1.08047353
139AR_25329375_ChIP-Seq_VCAP_Human1.07723852
140SUZ12_27294783_Chip-Seq_ESCs_Mouse1.06533135
141CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.06475798
142CDX2_22108803_ChIP-Seq_LS180_Human1.06025963
143KDM2B_26808549_Chip-Seq_REH_Human1.05821032
144NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.05685792
145FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.03875458
146AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.03799969
147YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.03507076
148FLI1_21867929_ChIP-Seq_TH2_Mouse1.03129914
149FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.02827535

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system3.51377680
2MP0005085_abnormal_gallbladder_physiolo3.23057986
3MP0003136_yellow_coat_color2.87495918
4MP0005365_abnormal_bile_salt2.85563780
5MP0004215_abnormal_myocardial_fiber2.79837674
6MP0005360_urolithiasis2.76331290
7MP0000569_abnormal_digit_pigmentation2.75984096
8MP0003195_calcinosis2.62572779
9MP0000751_myopathy2.52909883
10MP0008875_abnormal_xenobiotic_pharmacok2.47760808
11MP0004381_abnormal_hair_follicle2.38642174
12MP0004084_abnormal_cardiac_muscle2.25564048
13MP0005409_darkened_coat_color2.25475734
14MP0001986_abnormal_taste_sensitivity2.19664044
15MP0003724_increased_susceptibility_to2.16245600
16MP0005451_abnormal_body_composition2.16211151
17MP0009697_abnormal_copulation2.06770267
18MP0005171_absent_coat_pigmentation2.06700073
19MP0006072_abnormal_retinal_apoptosis1.97540946
20MP0009780_abnormal_chondrocyte_physiolo1.91723477
21MP0004130_abnormal_muscle_cell1.89586689
22MP0000566_synostosis1.87744922
23MP0009379_abnormal_foot_pigmentation1.81305172
24MP0001188_hyperpigmentation1.80940966
25MP0000920_abnormal_myelination1.79439067
26MP0002876_abnormal_thyroid_physiology1.79310981
27MP0003011_delayed_dark_adaptation1.65970340
28MP0005646_abnormal_pituitary_gland1.62366691
29MP0005332_abnormal_amino_acid1.61068469
30MP0004142_abnormal_muscle_tone1.60545794
31MP0006292_abnormal_olfactory_placode1.60375470
32MP0008775_abnormal_heart_ventricle1.60326070
33MP0003806_abnormal_nucleotide_metabolis1.59624306
34MP0000372_irregular_coat_pigmentation1.52004919
35MP0008058_abnormal_DNA_repair1.48488838
36MP0005253_abnormal_eye_physiology1.47461185
37MP0005379_endocrine/exocrine_gland_phen1.46769125
38MP0003880_abnormal_central_pattern1.45548989
39MP0004019_abnormal_vitamin_homeostasis1.44337487
40MP0002269_muscular_atrophy1.44173111
41MP0003690_abnormal_glial_cell1.40421954
42MP0003252_abnormal_bile_duct1.40334482
43MP0002106_abnormal_muscle_physiology1.39975228
44MP0002102_abnormal_ear_morphology1.38271796
45MP0003718_maternal_effect1.36917456
46MP0006054_spinal_hemorrhage1.34116692
47MP0005620_abnormal_muscle_contractility1.33184698
48MP0001764_abnormal_homeostasis1.32440152
49MP0009764_decreased_sensitivity_to1.32325462
50MP0001905_abnormal_dopamine_level1.31474006
51MP0010094_abnormal_chromosome_stability1.31471151
52MP0004742_abnormal_vestibular_system1.30170184
53MP0005551_abnormal_eye_electrophysiolog1.29490989
54MP0010329_abnormal_lipoprotein_level1.29053463
55MP0003941_abnormal_skin_development1.28301984
56MP0006276_abnormal_autonomic_nervous1.25133857
57MP0005369_muscle_phenotype1.24672836
58MP0008877_abnormal_DNA_methylation1.23847926
59MP0001984_abnormal_olfaction1.21683246
60MP0006036_abnormal_mitochondrial_physio1.20205138
61MP0003186_abnormal_redox_activity1.19909289
62MP0004484_altered_response_of1.18296141
63MP0006082_CNS_inflammation1.17710240
64MP0003646_muscle_fatigue1.17097172
65MP0000013_abnormal_adipose_tissue1.17000870
66MP0005075_abnormal_melanosome_morpholog1.16711274
67MP0004147_increased_porphyrin_level1.16202280
68MP0002972_abnormal_cardiac_muscle1.15265153
69MP0001486_abnormal_startle_reflex1.14779038
70MP0003950_abnormal_plasma_membrane1.13193897
71MP0000427_abnormal_hair_cycle1.13175441
72MP0005083_abnormal_biliary_tract1.13084366
73MP0002118_abnormal_lipid_homeostasis1.12999899
74MP0002938_white_spotting1.10187929
75MP0004087_abnormal_muscle_fiber1.09965318
76MP0001529_abnormal_vocalization1.09954316
77MP0002009_preneoplasia1.09738499
78MP0002234_abnormal_pharynx_morphology1.09631960
79MP0005266_abnormal_metabolism1.09466116
80MP0002837_dystrophic_cardiac_calcinosis1.09319710
81MP0000747_muscle_weakness1.08226226
82MP0002132_abnormal_respiratory_system1.07496483
83MP0002638_abnormal_pupillary_reflex1.07313334
84MP0005084_abnormal_gallbladder_morpholo1.06346460
85MP0000749_muscle_degeneration1.06051289
86MP0002277_abnormal_respiratory_mucosa1.03486256
87MP0010386_abnormal_urinary_bladder1.02225111
88MP0005647_abnormal_sex_gland1.02056858
89MP0005584_abnormal_enzyme/coenzyme_acti1.01112565
90MP0001666_abnormal_nutrient_absorption0.99974570
91MP0002148_abnormal_hypersensitivity_rea0.99547312
92MP0002108_abnormal_muscle_morphology0.98403886
93MP0002736_abnormal_nociception_after0.98071830
94MP0004085_abnormal_heartbeat0.97723792
95MP0008057_abnormal_DNA_replication0.97628355
96MP0005385_cardiovascular_system_phenoty0.97436099
97MP0001544_abnormal_cardiovascular_syste0.97436099
98MP0002095_abnormal_skin_pigmentation0.97229150
99MP0004145_abnormal_muscle_electrophysio0.95174307
100MP0005645_abnormal_hypothalamus_physiol0.93908960
101MP0000750_abnormal_muscle_regeneration0.93416236
102MP0005174_abnormal_tail_pigmentation0.92929121
103MP0009046_muscle_twitch0.91487378
104MP0003868_abnormal_feces_composition0.90954969
105MP0000026_abnormal_inner_ear0.90241942
106MP0000759_abnormal_skeletal_muscle0.90201861
107MP0001485_abnormal_pinna_reflex0.89000037
108MP0002272_abnormal_nervous_system0.88142304
109MP0008260_abnormal_autophagy0.87979383
110MP0005670_abnormal_white_adipose0.87002019
111MP0005187_abnormal_penis_morphology0.86404789
112MP0005503_abnormal_tendon_morphology0.86217373
113MP0005535_abnormal_body_temperature0.85424113
114MP0002138_abnormal_hepatobiliary_system0.83429257
115MP0009785_altered_susceptibility_to0.83217125
116MP0000015_abnormal_ear_pigmentation0.82984510
117MP0003137_abnormal_impulse_conducting0.82969880
118MP0002163_abnormal_gland_morphology0.81864454
119MP0005636_abnormal_mineral_homeostasis0.81737452
120MP0005423_abnormal_somatic_nervous0.80993364
121MP0000358_abnormal_cell_content/0.80875945
122MP0008872_abnormal_physiological_respon0.79637833
123MP0000516_abnormal_urinary_system0.78622178
124MP0005367_renal/urinary_system_phenotyp0.78622178
125MP0002127_abnormal_cardiovascular_syste0.78078533
126MP0009765_abnormal_xenobiotic_induced0.76130557
127MP0003567_abnormal_fetal_cardiomyocyte0.72905763
128MP0000230_abnormal_systemic_arterial0.72505853
129MP0003787_abnormal_imprinting0.72293590
130MP0006035_abnormal_mitochondrial_morpho0.72151010
131MP0002971_abnormal_brown_adipose0.71251563
132MP0002160_abnormal_reproductive_system0.71002080
133MP0001963_abnormal_hearing_physiology0.70653160
134MP0002419_abnormal_innate_immunity0.70511507
135MP0001835_abnormal_antigen_presentation0.70291770
136MP0002090_abnormal_vision0.70276396
137MP0000762_abnormal_tongue_morphology0.69594604
138MP0005408_hypopigmentation0.68971368
139MP0002933_joint_inflammation0.67863493
140MP0002229_neurodegeneration0.67765693
141MP0001501_abnormal_sleep_pattern0.66848124
142MP0002332_abnormal_exercise_endurance0.66428175
143MP0008469_abnormal_protein_level0.66357154
144MP0001661_extended_life_span0.65119721
145MP0005671_abnormal_response_to0.63001112
146MP0005595_abnormal_vascular_smooth0.62110498
147MP0009763_increased_sensitivity_to0.62087530
148MP0002067_abnormal_sensory_capabilities0.61907007
149MP0004036_abnormal_muscle_relaxation0.61435777
150MP0005330_cardiomyopathy0.60895685

Predicted human phenotypes

RankGene SetZ-score
1Nemaline bodies (HP:0003798)4.37414425
2Muscle fiber inclusion bodies (HP:0100299)4.24329534
3Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.10475450
4Acute necrotizing encephalopathy (HP:0006965)4.03116337
5Prolonged partial thromboplastin time (HP:0003645)4.02693079
6Acute encephalopathy (HP:0006846)3.77636098
7Exercise-induced muscle cramps (HP:0003710)3.57590064
8Abnormal mitochondria in muscle tissue (HP:0008316)3.52717745
9Hepatic necrosis (HP:0002605)3.49517862
10Mitochondrial inheritance (HP:0001427)3.49137641
11Progressive macrocephaly (HP:0004481)3.43900652
12Cerebral edema (HP:0002181)3.35705117
13Abnormality of aromatic amino acid family metabolism (HP:0004338)3.34256006
14Hepatocellular necrosis (HP:0001404)3.31925522
15Renal Fanconi syndrome (HP:0001994)3.18824986
16Intrahepatic cholestasis (HP:0001406)3.14333740
17Renal cortical cysts (HP:0000803)3.05211238
18Conjugated hyperbilirubinemia (HP:0002908)3.02638305
19Parakeratosis (HP:0001036)3.01586501
20Pancreatic cysts (HP:0001737)2.93868154
21Increased CSF lactate (HP:0002490)2.93566121
22Methylmalonic acidemia (HP:0002912)2.92652536
23Calf muscle hypertrophy (HP:0008981)2.89651629
24Hypothermia (HP:0002045)2.89349234
25Lipid accumulation in hepatocytes (HP:0006561)2.86881865
26Pancreatic fibrosis (HP:0100732)2.81566634
27Joint hemorrhage (HP:0005261)2.81201171
28Increased hepatocellular lipid droplets (HP:0006565)2.79320693
29Hyperalaninemia (HP:0003348)2.75557307
30Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.75557307
31Abnormality of alanine metabolism (HP:0010916)2.75557307
32Abnormality of the calf musculature (HP:0001430)2.68308010
33Optic disc pallor (HP:0000543)2.66605066
34Facial diplegia (HP:0001349)2.60604765
353-Methylglutaconic aciduria (HP:0003535)2.57963355
36Abnormality of dicarboxylic acid metabolism (HP:0010995)2.54035995
37Dicarboxylic aciduria (HP:0003215)2.54035995
38Generalized aminoaciduria (HP:0002909)2.53772957
39Hypoglycemic coma (HP:0001325)2.53086520
40Myoglobinuria (HP:0002913)2.49259916
41Aplasia/Hypoplasia of the tongue (HP:0010295)2.45357482
42Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.44798404
43Abnormality of urine glucose concentration (HP:0011016)2.42987231
44Glycosuria (HP:0003076)2.42987231
45Type 1 muscle fiber predominance (HP:0003803)2.42444347
46Exercise-induced myalgia (HP:0003738)2.41281941
47Increased intramyocellular lipid droplets (HP:0012240)2.39366224
48Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.39013438
49Rhabdomyolysis (HP:0003201)2.38225881
50Hyperlipoproteinemia (HP:0010980)2.37909868
51Lethargy (HP:0001254)2.37492953
52Lactic acidosis (HP:0003128)2.37021268
53Abnormality of renal resorption (HP:0011038)2.34311678
54Increased muscle lipid content (HP:0009058)2.33559515
55Abnormality of methionine metabolism (HP:0010901)2.33356988
56Hypophosphatemic rickets (HP:0004912)2.31626771
57Congenital sensorineural hearing impairment (HP:0008527)2.29911407
58Abnormality of secondary sexual hair (HP:0009888)2.28366181
59Abnormality of the axillary hair (HP:0100134)2.28366181
60Concave nail (HP:0001598)2.27499125
61Patchy hypopigmentation of hair (HP:0011365)2.27294007
62Abnormality of aspartate family amino acid metabolism (HP:0010899)2.27207526
63Type I transferrin isoform profile (HP:0003642)2.22367049
64Abnormality of fatty-acid metabolism (HP:0004359)2.21697390
65Methylmalonic aciduria (HP:0012120)2.21425844
66Ketosis (HP:0001946)2.21014512
67Areflexia of lower limbs (HP:0002522)2.20983616
68Aplasia/Hypoplasia of the tibia (HP:0005772)2.20368709
69Absent phalangeal crease (HP:0006109)2.20064266
70Exercise intolerance (HP:0003546)2.19220441
71Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.18959167
72Central scotoma (HP:0000603)2.18112127
73Xanthomatosis (HP:0000991)2.17853145
74Abnormal ciliary motility (HP:0012262)2.17614788
75Hyperventilation (HP:0002883)2.17274702
76Hyporeflexia of lower limbs (HP:0002600)2.14223092
77Nephronophthisis (HP:0000090)2.14010396
78White forelock (HP:0002211)2.13019531
79Molar tooth sign on MRI (HP:0002419)2.09220791
80Abnormality of midbrain morphology (HP:0002418)2.09220791
81CNS demyelination (HP:0007305)2.08926803
82Metabolic acidosis (HP:0001942)2.08918536
83Congenital, generalized hypertrichosis (HP:0004540)2.08272993
84Cerebral palsy (HP:0100021)2.08104305
85Abnormality of placental membranes (HP:0011409)2.06514431
86Amniotic constriction ring (HP:0009775)2.06514431
87Sudden death (HP:0001699)2.05055489
88Volvulus (HP:0002580)2.04819296
89Renal tubular dysfunction (HP:0000124)2.02531987
90Leukodystrophy (HP:0002415)2.02295674
91Abnormal finger flexion creases (HP:0006143)2.01358024
92Muscle hypertrophy of the lower extremities (HP:0008968)2.00506013
93Nephrogenic diabetes insipidus (HP:0009806)1.98427515
94Congenital primary aphakia (HP:0007707)1.98356591
95Increased serum lactate (HP:0002151)1.97970300
96Fat malabsorption (HP:0002630)1.97742453
97Palpitations (HP:0001962)1.97706760
98Abnormality of glycine metabolism (HP:0010895)1.97608163
99Abnormality of serine family amino acid metabolism (HP:0010894)1.97608163
100Hyperglycinuria (HP:0003108)1.96459764
101Thyroid-stimulating hormone excess (HP:0002925)1.95964401
102Rimmed vacuoles (HP:0003805)1.95034252
103Hypoglycemic seizures (HP:0002173)1.92758194
104Enlarged kidneys (HP:0000105)1.91801119
105Colon cancer (HP:0003003)1.91226782
106Short tibia (HP:0005736)1.90339784
107True hermaphroditism (HP:0010459)1.88939552
108Vomiting (HP:0002013)1.88861745
109Proximal tubulopathy (HP:0000114)1.88075154
110Steatorrhea (HP:0002570)1.86895350
111Respiratory failure (HP:0002878)1.86576961
112Gait imbalance (HP:0002141)1.85641489
113Complement deficiency (HP:0004431)1.84212180
114Ketoacidosis (HP:0001993)1.84170989
115Abnormality of serum amino acid levels (HP:0003112)1.83780874
116Hyperammonemia (HP:0001987)1.83075291
117Abnormality of monocarboxylic acid metabolism (HP:0010996)1.82944302
118Fair hair (HP:0002286)1.82457857
119Symptomatic seizures (HP:0011145)1.81653799
120Abnormality of chromosome stability (HP:0003220)1.81540376
121Tubulointerstitial nephritis (HP:0001970)1.80379804
122Distal arthrogryposis (HP:0005684)1.80292130
123Abnormality of the renal medulla (HP:0100957)1.79456311
124Decreased central vision (HP:0007663)1.78429767
125Abnormality of glycolysis (HP:0004366)1.78047584
126Increased serum pyruvate (HP:0003542)1.78047584
127Exertional dyspnea (HP:0002875)1.77523079
128Anomalous pulmonary venous return (HP:0010772)1.77262824
129Duplicated collecting system (HP:0000081)1.77167005
130Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.76019835
131Decreased activity of mitochondrial respiratory chain (HP:0008972)1.76019835
132Abnormality of vitamin B metabolism (HP:0004340)1.74196619
133Hyperglycinemia (HP:0002154)1.73608083
134Reduced antithrombin III activity (HP:0001976)1.73607284
135Prolonged neonatal jaundice (HP:0006579)1.72960705
136Large for gestational age (HP:0001520)1.72831778
137Abnormality of the renal cortex (HP:0011035)1.72266692
138Medial flaring of the eyebrow (HP:0010747)1.72036875
139Hypoalphalipoproteinemia (HP:0003233)1.71924935
140Retinal dysplasia (HP:0007973)1.71485753
141EMG: myopathic abnormalities (HP:0003458)1.71109594
142Abnormal respiratory motile cilium physiology (HP:0012261)1.70976573
143Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.70549545
144Microvesicular hepatic steatosis (HP:0001414)1.70348199
145Neck muscle weakness (HP:0000467)1.69905962
146Absent/shortened dynein arms (HP:0200106)1.67953177
147Dynein arm defect of respiratory motile cilia (HP:0012255)1.67953177
148Hypobetalipoproteinemia (HP:0003563)1.66828910
149Respiratory distress (HP:0002098)1.66814731
150Epidermoid cyst (HP:0200040)1.66608953
151Abnormality of the level of lipoprotein cholesterol (HP:0010979)1.66262010

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NEK16.21685532
2TNIK3.84737793
3STK163.24305922
4INSRR3.10132087
5CASK2.95604889
6FRK2.85237003
7EIF2AK32.84815458
8IRAK32.58610482
9MAP4K22.46735405
10BMPR1B2.30305096
11STK392.28195444
12TRIM282.26888086
13RIPK12.15463025
14BCKDK2.14740030
15WNK32.01504139
16OBSCN1.95243319
17MUSK1.81821563
18OXSR11.74286352
19PLK41.71045421
20GRK71.70669010
21PINK11.69775026
22PKN11.64518613
23ZAK1.63659573
24BMPR21.62444039
25IRAK41.58598565
26PBK1.56307272
27TIE11.54040641
28NEK21.52664674
29ADRBK21.50791412
30MAPKAPK31.50210382
31TXK1.50105060
32MAP3K141.49201462
33NUAK11.46936080
34MAPK151.44541303
35IRAK21.43966471
36IRAK11.43053041
37NEK61.40748342
38BLK1.40659665
39LIMK11.39442942
40PIK3CG1.38406455
41GRK11.36714443
42FLT31.35569148
43BUB11.33016030
44MAPK131.21859922
45MAP2K71.18802295
46SIK31.16269049
47PDK21.15925016
48MAPKAPK51.14978738
49MYLK1.13814296
50PIK3CA1.13646843
51BCR1.13318121
52TEC1.11675278
53EPHB11.09411484
54EIF2AK11.08965454
55ACVR1B1.08824583
56VRK11.08687863
57EIF2AK21.03956051
58PRKCI1.03613867
59PRPF4B1.01056991
60NLK0.94994538
61CDK190.90126073
62WNK40.88577695
63WEE10.88212758
64CDK30.87392210
65ERBB40.85614526
66PHKG20.85204239
67PHKG10.85204239
68MKNK20.84061473
69PAK30.82684199
70BRSK20.82383711
71MAP3K120.80548689
72EPHA40.79701177
73PRKCE0.77868831
74PRKCQ0.77463108
75CAMK2D0.77344444
76PLK30.76660111
77TRPM70.75979471
78IKBKE0.75745973
79CAMK2B0.75274412
80SRPK10.75095465
81MAP3K60.73811113
82MAPK120.73779715
83STK240.73297907
84CAMK2G0.72436264
85YES10.71927303
86DYRK20.71821278
87PLK20.71171995
88TTK0.70897033
89MAP3K40.68953993
90MST40.68219367
91TGFBR10.67009528
92PRKCG0.66190077
93STK30.64239963
94CAMK2A0.64006068
95IKBKB0.63236841
96FES0.61310025
97PRKAA20.60591754
98LYN0.59054641
99EPHA30.58200070
100AKT30.56988848
101AURKB0.56641084
102CLK10.56378555
103ADRBK10.55813938
104SCYL20.55410303
105CCNB10.54975866
106PRKG10.54909714
107RPS6KA50.53781392
108TSSK60.53494404
109PLK10.51946833
110ABL20.51435774
111CDK80.51372454
112KIT0.51074398
113SGK2230.50351308
114SGK4940.50351308
115ERBB30.49890198
116MAP2K60.49361957
117MAPK70.49231887
118ROCK10.49009359
119PRKACA0.48867502
120TESK10.48788151
121CSNK1G20.48617606
122FGFR20.46140524
123FER0.45716349
124FGFR10.45301905
125BTK0.45285796
126PRKACB0.44686884
127CSNK2A20.43783710
128MAP2K40.43498927
129NEK90.43045825
130DYRK1A0.42469267
131VRK20.42158677
132NME20.41929804
133TNK20.41600924
134MAPK40.41501806
135RPS6KA40.41315033
136STK40.41035277
137FGR0.41027852
138MKNK10.40935611
139ATM0.39011404
140PIM20.38933642
141TAOK30.38637233
142TGFBR20.37623060
143DAPK30.37515419
144CSNK1G10.37033899
145DYRK30.36848046
146CSNK1A1L0.36382986
147STK38L0.35518818
148CSNK1G30.32975329
149CSNK2A10.32728173
150ROCK20.32111018
151MET0.29446241
152ILK0.28348282

Predicted pathways (KEGG)

RankGene SetZ-score
1Fatty acid elongation_Homo sapiens_hsa000623.18231335
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.95172757
3Oxidative phosphorylation_Homo sapiens_hsa001902.74587115
4Primary bile acid biosynthesis_Homo sapiens_hsa001202.60409208
5Sulfur metabolism_Homo sapiens_hsa009202.37942654
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.35485135
7Propanoate metabolism_Homo sapiens_hsa006402.34949547
8Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.25193891
9Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.21189251
10Peroxisome_Homo sapiens_hsa041462.16461059
11Histidine metabolism_Homo sapiens_hsa003402.13477008
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.10014456
13Proteasome_Homo sapiens_hsa030502.05540667
14Parkinsons disease_Homo sapiens_hsa050122.02336752
15Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.00553356
16Fatty acid degradation_Homo sapiens_hsa000711.96565940
17Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.95452723
18Steroid hormone biosynthesis_Homo sapiens_hsa001401.93754557
19Steroid biosynthesis_Homo sapiens_hsa001001.93219872
20Butanoate metabolism_Homo sapiens_hsa006501.91793968
21beta-Alanine metabolism_Homo sapiens_hsa004101.83782636
22Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.81900565
23Chemical carcinogenesis_Homo sapiens_hsa052041.80171672
24Tryptophan metabolism_Homo sapiens_hsa003801.79398694
25Non-homologous end-joining_Homo sapiens_hsa034501.77947379
26Pentose and glucuronate interconversions_Homo sapiens_hsa000401.73865942
27Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.71902606
28Retinol metabolism_Homo sapiens_hsa008301.71714917
29Alzheimers disease_Homo sapiens_hsa050101.69848872
30Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.67557725
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.65553578
32Complement and coagulation cascades_Homo sapiens_hsa046101.65419333
33Homologous recombination_Homo sapiens_hsa034401.64938540
34Fatty acid metabolism_Homo sapiens_hsa012121.63612753
35Protein export_Homo sapiens_hsa030601.60142114
36Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.57983489
37Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.55116563
38Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.53348567
39Fanconi anemia pathway_Homo sapiens_hsa034601.51876857
40Staphylococcus aureus infection_Homo sapiens_hsa051501.50250026
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.49686866
42Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.34836613
43Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.34106842
44Tyrosine metabolism_Homo sapiens_hsa003501.33340230
45Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.29416172
46Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.27617033
47Cysteine and methionine metabolism_Homo sapiens_hsa002701.25687103
48Arginine and proline metabolism_Homo sapiens_hsa003301.25621409
49RNA degradation_Homo sapiens_hsa030181.25311456
50Basal transcription factors_Homo sapiens_hsa030221.24646576
51Arachidonic acid metabolism_Homo sapiens_hsa005901.24510220
52Huntingtons disease_Homo sapiens_hsa050161.21244271
53ABC transporters_Homo sapiens_hsa020101.18430649
54Ether lipid metabolism_Homo sapiens_hsa005651.15268461
55PPAR signaling pathway_Homo sapiens_hsa033201.15155850
56One carbon pool by folate_Homo sapiens_hsa006701.15121395
57Ribosome_Homo sapiens_hsa030101.14041216
58Phenylalanine metabolism_Homo sapiens_hsa003601.13776172
59Nucleotide excision repair_Homo sapiens_hsa034201.13368451
60Starch and sucrose metabolism_Homo sapiens_hsa005001.12386239
61Mismatch repair_Homo sapiens_hsa034301.09328088
62Vitamin digestion and absorption_Homo sapiens_hsa049771.08259226
63Sphingolipid metabolism_Homo sapiens_hsa006001.07438535
64Linoleic acid metabolism_Homo sapiens_hsa005911.06920446
65SNARE interactions in vesicular transport_Homo sapiens_hsa041301.03769928
66Caffeine metabolism_Homo sapiens_hsa002321.03505069
67Maturity onset diabetes of the young_Homo sapiens_hsa049501.02962320
68RNA polymerase_Homo sapiens_hsa030200.97068994
69alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.96871950
70Autoimmune thyroid disease_Homo sapiens_hsa053200.92163358
71Cardiac muscle contraction_Homo sapiens_hsa042600.91774883
72Purine metabolism_Homo sapiens_hsa002300.91409811
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91274814
74Folate biosynthesis_Homo sapiens_hsa007900.89122632
75Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.87662220
76Glutathione metabolism_Homo sapiens_hsa004800.84839902
77Metabolic pathways_Homo sapiens_hsa011000.83717310
78Pyruvate metabolism_Homo sapiens_hsa006200.83702874
79Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.81774045
80Phototransduction_Homo sapiens_hsa047440.77816036
81Arginine biosynthesis_Homo sapiens_hsa002200.77106275
82DNA replication_Homo sapiens_hsa030300.75349609
83Base excision repair_Homo sapiens_hsa034100.74948644
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71376576
85Intestinal immune network for IgA production_Homo sapiens_hsa046720.70976423
86RNA transport_Homo sapiens_hsa030130.68580330
87Rheumatoid arthritis_Homo sapiens_hsa053230.67925290
88Allograft rejection_Homo sapiens_hsa053300.67102578
89Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65705968
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.65653773
91Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.64361472
92Pyrimidine metabolism_Homo sapiens_hsa002400.61837541
93Biosynthesis of amino acids_Homo sapiens_hsa012300.60743321
94Lysine degradation_Homo sapiens_hsa003100.58877434
95Pentose phosphate pathway_Homo sapiens_hsa000300.57960413
96Circadian rhythm_Homo sapiens_hsa047100.57395481
97Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.57187142
98Graft-versus-host disease_Homo sapiens_hsa053320.55855009
99Dilated cardiomyopathy_Homo sapiens_hsa054140.49671093
100Vitamin B6 metabolism_Homo sapiens_hsa007500.45985358
101Olfactory transduction_Homo sapiens_hsa047400.45384818
102Serotonergic synapse_Homo sapiens_hsa047260.43794472
103Other glycan degradation_Homo sapiens_hsa005110.43671039
104Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42048573
105Taste transduction_Homo sapiens_hsa047420.40933992
106Sulfur relay system_Homo sapiens_hsa041220.40674637
107Asthma_Homo sapiens_hsa053100.39523861
108Systemic lupus erythematosus_Homo sapiens_hsa053220.39330077
109Fat digestion and absorption_Homo sapiens_hsa049750.39137981
110TGF-beta signaling pathway_Homo sapiens_hsa043500.38232371
111African trypanosomiasis_Homo sapiens_hsa051430.37937739
112Malaria_Homo sapiens_hsa051440.37655365
113Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.37340865
114Glycerolipid metabolism_Homo sapiens_hsa005610.36996145
115Regulation of autophagy_Homo sapiens_hsa041400.34573494
116Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.34380899
117Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.33209625
118Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.33072228
119Selenocompound metabolism_Homo sapiens_hsa004500.32705853
120Fatty acid biosynthesis_Homo sapiens_hsa000610.31975382
121Nicotine addiction_Homo sapiens_hsa050330.31568442
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.28846918
123Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28641215
124Oocyte meiosis_Homo sapiens_hsa041140.28481023
125Glucagon signaling pathway_Homo sapiens_hsa049220.27295060
126Ovarian steroidogenesis_Homo sapiens_hsa049130.26129329
127Collecting duct acid secretion_Homo sapiens_hsa049660.24500812
128Glycerophospholipid metabolism_Homo sapiens_hsa005640.24206118
129Bile secretion_Homo sapiens_hsa049760.23732767
130Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.22622110
131Carbon metabolism_Homo sapiens_hsa012000.21713971
132Primary immunodeficiency_Homo sapiens_hsa053400.20654223
133RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.18219857
134Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.18205287
135Phagosome_Homo sapiens_hsa041450.16234448
136Nitrogen metabolism_Homo sapiens_hsa009100.13527405
137NF-kappa B signaling pathway_Homo sapiens_hsa040640.12999389

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