RMDN2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.50068101
2L-phenylalanine catabolic process (GO:0006559)7.50068101
3L-phenylalanine metabolic process (GO:0006558)7.13465757
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.13465757
5aromatic amino acid family catabolic process (GO:0009074)6.64363772
6bile acid biosynthetic process (GO:0006699)6.08082218
7triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.93668490
8indole-containing compound catabolic process (GO:0042436)5.90811783
9indolalkylamine catabolic process (GO:0046218)5.90811783
10tryptophan catabolic process (GO:0006569)5.90811783
11kynurenine metabolic process (GO:0070189)5.79507937
12alpha-linolenic acid metabolic process (GO:0036109)5.77577353
13glyoxylate metabolic process (GO:0046487)5.75073147
14tryptophan metabolic process (GO:0006568)5.58119660
15peptidyl-glutamic acid carboxylation (GO:0017187)5.38672276
16protein carboxylation (GO:0018214)5.38672276
17high-density lipoprotein particle remodeling (GO:0034375)5.36008140
18sulfur amino acid catabolic process (GO:0000098)5.34980163
19urea cycle (GO:0000050)5.33687090
20urea metabolic process (GO:0019627)5.33687090
21negative regulation of fibrinolysis (GO:0051918)5.30890046
22cysteine metabolic process (GO:0006534)5.26674579
23regulation of protein activation cascade (GO:2000257)5.21490223
24complement activation, alternative pathway (GO:0006957)5.20232543
25regulation of fibrinolysis (GO:0051917)5.10841705
26bile acid metabolic process (GO:0008206)5.10248775
27nitrogen cycle metabolic process (GO:0071941)4.99301516
28fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.95052451
29regulation of complement activation (GO:0030449)4.91114720
30aromatic amino acid family metabolic process (GO:0009072)4.81419978
31homocysteine metabolic process (GO:0050667)4.73582652
32serine family amino acid catabolic process (GO:0009071)4.72639377
33tyrosine metabolic process (GO:0006570)4.69775057
34reverse cholesterol transport (GO:0043691)4.65040846
35regulation of triglyceride catabolic process (GO:0010896)4.62637585
36lysine metabolic process (GO:0006553)4.53953975
37lysine catabolic process (GO:0006554)4.53953975
38protein-lipid complex remodeling (GO:0034368)4.52856678
39macromolecular complex remodeling (GO:0034367)4.52856678
40plasma lipoprotein particle remodeling (GO:0034369)4.52856678
41ethanol oxidation (GO:0006069)4.51880757
42triglyceride homeostasis (GO:0070328)4.49252356
43acylglycerol homeostasis (GO:0055090)4.49252356
44amino-acid betaine metabolic process (GO:0006577)4.48541881
45regulation of cholesterol esterification (GO:0010872)4.46172921
46alpha-amino acid catabolic process (GO:1901606)4.43833562
47benzene-containing compound metabolic process (GO:0042537)4.40903171
48plasma lipoprotein particle clearance (GO:0034381)4.30987692
49bile acid and bile salt transport (GO:0015721)4.29772207
50coenzyme catabolic process (GO:0009109)4.27199967
51indolalkylamine metabolic process (GO:0006586)4.25251504
52cellular glucuronidation (GO:0052695)4.20566048
53negative regulation of cholesterol transport (GO:0032375)4.20552494
54negative regulation of sterol transport (GO:0032372)4.20552494
55cellular ketone body metabolic process (GO:0046950)4.20477117
56glycine metabolic process (GO:0006544)4.16666083
57amine catabolic process (GO:0009310)4.15003042
58cellular biogenic amine catabolic process (GO:0042402)4.15003042
59phospholipid efflux (GO:0033700)4.13555381
60cellular amino acid catabolic process (GO:0009063)4.11685223
61cholesterol efflux (GO:0033344)4.11395665
62aldehyde catabolic process (GO:0046185)4.09996585
63imidazole-containing compound metabolic process (GO:0052803)4.07377688
64serine family amino acid metabolic process (GO:0009069)3.96513799
65glutamate metabolic process (GO:0006536)3.91907615
66omega-hydroxylase P450 pathway (GO:0097267)3.88739574
67fibrinolysis (GO:0042730)3.85763246
68short-chain fatty acid metabolic process (GO:0046459)3.83125234
69plasma lipoprotein particle assembly (GO:0034377)3.82203770
70very-low-density lipoprotein particle assembly (GO:0034379)3.81551997
71cellular modified amino acid catabolic process (GO:0042219)3.80772037
72low-density lipoprotein particle remodeling (GO:0034374)3.78247995
73serine family amino acid biosynthetic process (GO:0009070)3.77222027
74blood coagulation, intrinsic pathway (GO:0007597)3.73837832
75cofactor catabolic process (GO:0051187)3.73056971
76uronic acid metabolic process (GO:0006063)3.72762722
77glucuronate metabolic process (GO:0019585)3.72762722
78arginine metabolic process (GO:0006525)3.70892094
79organic acid catabolic process (GO:0016054)3.68281551
80carboxylic acid catabolic process (GO:0046395)3.68281551
81epoxygenase P450 pathway (GO:0019373)3.66245467
82cytolysis (GO:0019835)3.64542412
83negative regulation of complement activation (GO:0045916)3.64233879
84cholesterol homeostasis (GO:0042632)3.63349459
85complement activation, classical pathway (GO:0006958)3.62642232
86ketone body metabolic process (GO:1902224)3.62445918
87opsonization (GO:0008228)3.61873943
88exogenous drug catabolic process (GO:0042738)3.61795304
89complement activation (GO:0006956)3.61591750
90dicarboxylic acid biosynthetic process (GO:0043650)3.61204858
91acetyl-CoA metabolic process (GO:0006084)3.61038500
92response to nitrosative stress (GO:0051409)3.60297485
93drug catabolic process (GO:0042737)3.60211023
94protein activation cascade (GO:0072376)3.58761424
95positive regulation of lipid catabolic process (GO:0050996)3.57563757
96positive regulation of lipoprotein lipase activity (GO:0051006)3.56698129
97positive regulation of triglyceride lipase activity (GO:0061365)3.56698129
98sterol homeostasis (GO:0055092)3.56442123
99flavonoid metabolic process (GO:0009812)3.55590389
100xenobiotic catabolic process (GO:0042178)3.55024217
101negative regulation of lipase activity (GO:0060192)3.54840936
102monocarboxylic acid catabolic process (GO:0072329)3.52211216
103fatty acid oxidation (GO:0019395)3.51332804
104fatty acid beta-oxidation (GO:0006635)3.50991387
105negative regulation of protein activation cascade (GO:2000258)3.49168564
106oxidative demethylation (GO:0070989)3.37343119
107positive regulation of glycolytic process (GO:0045821)3.34389048
108regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.32245813
109signal peptide processing (GO:0006465)3.30503736
110drug metabolic process (GO:0017144)3.28940763
111regulation of glucokinase activity (GO:0033131)3.19999152
112regulation of hexokinase activity (GO:1903299)3.19999152
113glucocorticoid biosynthetic process (GO:0006704)3.19389410
114respiratory chain complex IV assembly (GO:0008535)3.15078018
115regulation of phospholipase A2 activity (GO:0032429)3.15030005
116androgen biosynthetic process (GO:0006702)3.14685189
117cullin deneddylation (GO:0010388)3.10978561
118estrogen biosynthetic process (GO:0006703)3.08108888
119phospholipid homeostasis (GO:0055091)3.08003760
120DNA double-strand break processing (GO:0000729)2.95878319
121regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.91078224
122androgen metabolic process (GO:0008209)2.90221968
123negative regulation of humoral immune response (GO:0002921)2.89741659
124cellular response to ethanol (GO:0071361)2.86251807
125rRNA methylation (GO:0031167)2.76297767
126regulation of cilium movement (GO:0003352)2.74748827
127angiotensin maturation (GO:0002003)2.74185340
128alkaloid metabolic process (GO:0009820)2.72706661
129estrogen metabolic process (GO:0008210)2.69632827
130fusion of sperm to egg plasma membrane (GO:0007342)2.69593495
131regulation of lipoprotein metabolic process (GO:0050746)2.69019048
132plasma lipoprotein particle organization (GO:0071827)2.68984645
133sperm motility (GO:0030317)2.67069926
134C21-steroid hormone biosynthetic process (GO:0006700)2.66044419
135acrosome reaction (GO:0007340)2.65316242
136protein deneddylation (GO:0000338)2.64160543
137regulation of integrin-mediated signaling pathway (GO:2001044)2.60059990
138branched-chain amino acid catabolic process (GO:0009083)2.59460931
139regulation of protein glycosylation (GO:0060049)2.58278309
140regulation of sulfur metabolic process (GO:0042762)2.56812364
141positive regulation of protein autophosphorylation (GO:0031954)2.55138701
142cytochrome complex assembly (GO:0017004)2.54813352
143xenobiotic metabolic process (GO:0006805)2.53398880
144positive regulation of macrophage derived foam cell differentiation (GO:0010744)2.51839395
145sterol transport (GO:0015918)2.50749857
146cholesterol transport (GO:0030301)2.50749857
147ethanol metabolic process (GO:0006067)2.50618669
148regulation of acyl-CoA biosynthetic process (GO:0050812)2.49062009
149urate metabolic process (GO:0046415)2.43226854
150fat-soluble vitamin biosynthetic process (GO:0042362)2.43205250
151sphingosine metabolic process (GO:0006670)2.42081766

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.16347911
2PPARA_22158963_ChIP-Seq_LIVER_Mouse6.96237648
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.91331652
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.41713133
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.21295027
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.89755819
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.89612513
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.52393017
9NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.81368733
10CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.79601602
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.82432098
12GBX2_23144817_ChIP-Seq_PC3_Human2.61221513
13CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.49580461
14TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.19724904
15AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.19544774
16FLI1_27457419_Chip-Seq_LIVER_Mouse2.17847244
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.07900840
18FUS_26573619_Chip-Seq_HEK293_Human2.07757480
19CDX2_19796622_ChIP-Seq_MESCs_Mouse2.06729928
20TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.03121414
21ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.7308723
22HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.95390057
23EZH2_27294783_Chip-Seq_NPCs_Mouse1.90300256
24CLOCK_20551151_ChIP-Seq_293T_Human1.85047704
25SUZ12_27294783_Chip-Seq_NPCs_Mouse1.84637984
26PCGF2_27294783_Chip-Seq_ESCs_Mouse1.84299761
27NFE2_27457419_Chip-Seq_LIVER_Mouse1.76525409
28P300_19829295_ChIP-Seq_ESCs_Human1.76460026
29PIAS1_25552417_ChIP-Seq_VCAP_Human1.74295680
30HTT_18923047_ChIP-ChIP_STHdh_Human1.72932788
31IGF1R_20145208_ChIP-Seq_DFB_Human1.69430988
32SMAD_19615063_ChIP-ChIP_OVARY_Human1.68297062
33GATA1_22025678_ChIP-Seq_K562_Human1.64689989
34SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.64180648
35UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.61406410
36SMAD4_21799915_ChIP-Seq_A2780_Human1.60447419
37BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.60348622
38CTBP2_25329375_ChIP-Seq_LNCAP_Human1.60157036
39ER_23166858_ChIP-Seq_MCF-7_Human1.59705375
40NANOG_18555785_Chip-Seq_ESCs_Mouse1.57797431
41PCGF2_27294783_Chip-Seq_NPCs_Mouse1.57062072
42FOXA2_19822575_ChIP-Seq_HepG2_Human1.52389858
43EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.49951417
44ZNF274_21170338_ChIP-Seq_K562_Hela1.49677547
45GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.49352603
46STAT3_23295773_ChIP-Seq_U87_Human1.47344456
47MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.47123026
48P53_22387025_ChIP-Seq_ESCs_Mouse1.45481768
49TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.44182872
50SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.43966671
51VDR_22108803_ChIP-Seq_LS180_Human1.42420446
52OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.42283998
53CBP_20019798_ChIP-Seq_JUKART_Human1.41163131
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.41163131
55AR_25329375_ChIP-Seq_VCAP_Human1.36721794
56FOXA1_21572438_ChIP-Seq_LNCaP_Human1.32956656
57HNF4A_19822575_ChIP-Seq_HepG2_Human1.32941906
58KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.32718935
59OCT4_21477851_ChIP-Seq_ESCs_Mouse1.32140308
60SALL4_22934838_ChIP-ChIP_CD34+_Human1.31284874
61FOXM1_26456572_ChIP-Seq_MCF-7_Human1.31031941
62E2F1_18555785_Chip-Seq_ESCs_Mouse1.31025584
63SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.30368467
64SUZ12_18555785_Chip-Seq_ESCs_Mouse1.29429297
65TCF4_23295773_ChIP-Seq_U87_Human1.28618191
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.28333987
67TCF4_22108803_ChIP-Seq_LS180_Human1.27612686
68NR3C1_21868756_ChIP-Seq_MCF10A_Human1.27349832
69CMYC_18555785_Chip-Seq_ESCs_Mouse1.27132390
70P300_18555785_Chip-Seq_ESCs_Mouse1.25808813
71STAT3_18555785_Chip-Seq_ESCs_Mouse1.25587949
72SOX2_19829295_ChIP-Seq_ESCs_Human1.23620149
73NANOG_19829295_ChIP-Seq_ESCs_Human1.23620149
74CJUN_26792858_Chip-Seq_BT549_Human1.23545964
75SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.23415588
76EWS_26573619_Chip-Seq_HEK293_Human1.22468665
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21456503
78CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21450443
79TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21223794
80STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.19995738
81EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.19106560
82OCT4_18555785_Chip-Seq_ESCs_Mouse1.17302882
83SOX2_18555785_Chip-Seq_ESCs_Mouse1.16360545
84RXRA_24833708_ChIP-Seq_LIVER_Mouse1.13905575
85PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.13495228
86EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12718085
87IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.12654585
88NFYA_21822215_ChIP-Seq_K562_Human1.12233314
89TAL1_26923725_Chip-Seq_HPCs_Mouse1.11185888
90HNFA_21074721_ChIP-Seq_CACO-2_Human1.11028304
91SMAD3_21741376_ChIP-Seq_EPCs_Human1.10693355
92SMAD4_21741376_ChIP-Seq_EPCs_Human1.10691101
93ELK1_19687146_ChIP-ChIP_HELA_Human1.10256346
94NMYC_18555785_Chip-Seq_ESCs_Mouse1.09122147
95ETV1_20927104_ChIP-Seq_GIST48_Human1.08703324
96TP63_23658742_ChIP-Seq_EP156T_Human1.07951113
97ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07921671
98KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07101899
99RARG_19884340_ChIP-ChIP_MEFs_Mouse1.07087073
100SALL1_21062744_ChIP-ChIP_HESCs_Human1.06782367
101TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06606154
102PCGF4_22325352_ChIP-Seq_293T-Rex_Human1.04906673
103CTCF_18555785_Chip-Seq_ESCs_Mouse1.04874139
104NFYB_21822215_ChIP-Seq_K562_Human1.04852159
105STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.04012635
106TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02710310
107PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.00862048
108IRF8_22096565_ChIP-ChIP_GC-B_Human0.99684866
109SOX2_27498859_Chip-Seq_STOMACH_Mouse0.95591405
110CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.93716934
111THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.90878552
112GATA4_25053715_ChIP-Seq_YYC3_Human0.88355618
113ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.87207990
114AUTS2_25519132_ChIP-Seq_293T-REX_Human0.85299223
115SALL4_18804426_ChIP-ChIP_XEN_Mouse0.84107017
116BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.80363264
117Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.77795898
118TAF15_26573619_Chip-Seq_HEK293_Human0.76731326
119NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.75836184
120NRF2_20460467_ChIP-Seq_MEFs_Mouse0.75836184
121SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.74921872
122KAP1_22055183_ChIP-Seq_ESCs_Mouse0.74792536
123AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.72014489
124RARA_24833708_ChIP-Seq_LIVER_Mouse0.71471062
125GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.70918280
126SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.69247462
127ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.69226633
128ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.67629877
129PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.66935575
130RAD21_21589869_ChIP-Seq_MESCs_Mouse0.66686753
131STAT1_17558387_ChIP-Seq_HELA_Human0.62670160
132ESR2_21235772_ChIP-Seq_MCF-7_Human0.62228336
133RARB_24833708_ChIP-Seq_LIVER_Mouse0.61055184
134CEBPB_22108803_ChIP-Seq_LS180_Human0.60993611
135PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.60034146
136FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.59877977
137ESET_19884257_ChIP-Seq_ESCs_Mouse0.59349861
138AR_20517297_ChIP-Seq_VCAP_Human0.59279813
139PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.58425870
140P53_21459846_ChIP-Seq_SAOS-2_Human0.56796524
141ESR1_21235772_ChIP-Seq_MCF-7_Human0.55934738
142BCAT_22108803_ChIP-Seq_LS180_Human0.55877122
143ESR1_20079471_ChIP-ChIP_T-47D_Human0.55763615
144NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.55573093
145EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.54911383
146CBP_21632823_ChIP-Seq_H3396_Human0.54548714
147RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.54246087
148FOXA1_25552417_ChIP-Seq_VCAP_Human0.53146423
149MYC_19915707_ChIP-ChIP_AK7_Human0.51977638
150ZNF263_19887448_ChIP-Seq_K562_Human0.51390829
151PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.51154789
152TRIM28_21343339_ChIP-Seq_HEK293_Human0.50508978
153BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.48814604
154RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.48582506
155CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.48158985
156CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.47599739
157FOXO3_23340844_ChIP-Seq_DLD1_Human0.46952955
158ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.46494748
159STAT3_1855785_ChIP-Seq_MESCs_Mouse0.45845477
160FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.44567724
161GATA1_19941826_ChIP-Seq_K562_Human0.44513089
162ERG_20517297_ChIP-Seq_VCAP_Human0.43500001
163PPAR_26484153_Chip-Seq_NCI-H1993_Human0.43072008
164CRX_20693478_ChIP-Seq_RETINA_Mouse0.42929463
165SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.42872658
166SOX2_20726797_ChIP-Seq_SW620_Human0.42805625
167LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.41741532
168TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.41680519
169EGR1_19032775_ChIP-ChIP_M12_Human0.41349131
170FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.41097284
171SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.40898089
172GATA2_19941826_ChIP-Seq_K562_Human0.40859257
173SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.40256435
174NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.39814756
175STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.39285925
176CDX2_20551321_ChIP-Seq_CACO-2_Human0.38490242
177SPI1_26923725_Chip-Seq_HPCs_Mouse0.38464919
178LXR_22292898_ChIP-Seq_THP-1_Human0.38247064
179GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.38022810
180CDX2_22108803_ChIP-Seq_LS180_Human0.37883010

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.36787140
2MP0005360_urolithiasis7.14314107
3MP0005085_abnormal_gallbladder_physiolo6.35656526
4MP0005365_abnormal_bile_salt6.00930852
5MP0008875_abnormal_xenobiotic_pharmacok5.37449676
6MP0003806_abnormal_nucleotide_metabolis4.53639014
7MP0003252_abnormal_bile_duct3.83151108
8MP0000569_abnormal_digit_pigmentation3.82941600
9MP0010329_abnormal_lipoprotein_level3.52417638
10MP0005083_abnormal_biliary_tract3.05745080
11MP0009840_abnormal_foam_cell2.92523698
12MP0003195_calcinosis2.84878103
13MP0005332_abnormal_amino_acid2.67915217
14MP0001666_abnormal_nutrient_absorption2.54258978
15MP0009780_abnormal_chondrocyte_physiolo2.15404920
16MP0000609_abnormal_liver_physiology2.11083498
17MP0003191_abnormal_cellular_cholesterol2.11044827
18MP0002118_abnormal_lipid_homeostasis2.09653200
19MP0006054_spinal_hemorrhage2.09602813
20MP0004019_abnormal_vitamin_homeostasis1.96294338
21MP0005319_abnormal_enzyme/_coenzyme1.90933873
22MP0003868_abnormal_feces_composition1.88678689
23MP0002138_abnormal_hepatobiliary_system1.81994729
24MP0000015_abnormal_ear_pigmentation1.74324201
25MP0002090_abnormal_vision1.71514691
26MP0003950_abnormal_plasma_membrane1.71067277
27MP0009697_abnormal_copulation1.68397907
28MP0004147_increased_porphyrin_level1.67856036
29MP0005584_abnormal_enzyme/coenzyme_acti1.61071498
30MP0001764_abnormal_homeostasis1.61021642
31MP0000372_irregular_coat_pigmentation1.48240002
32MP0004043_abnormal_pH_regulation1.47700437
33MP0005379_endocrine/exocrine_gland_phen1.44979860
34MP0003183_abnormal_peptide_metabolism1.42528474
35MP0008004_abnormal_stomach_pH1.41706491
36MP0003186_abnormal_redox_activity1.40597612
37MP0010386_abnormal_urinary_bladder1.38570140
38MP0005647_abnormal_sex_gland1.34273091
39MP0003011_delayed_dark_adaptation1.34154335
40MP0008877_abnormal_DNA_methylation1.32434606
41MP0002102_abnormal_ear_morphology1.26628404
42MP0005451_abnormal_body_composition1.25049604
43MP0009643_abnormal_urine_homeostasis1.25043894
44MP0010368_abnormal_lymphatic_system1.19785613
45MP0003786_premature_aging1.18529790
46MP0000598_abnormal_liver_morphology1.18508717
47MP0003656_abnormal_erythrocyte_physiolo1.17645770
48MP0003646_muscle_fatigue1.11928761
49MP0000343_altered_response_to1.11622023
50MP0008058_abnormal_DNA_repair1.11249773
51MP0000639_abnormal_adrenal_gland1.10899484
52MP0001984_abnormal_olfaction1.09647589
53MP0005275_abnormal_skin_tensile1.07445944
54MP0005310_abnormal_salivary_gland1.07350889
55MP0003705_abnormal_hypodermis_morpholog1.06139187
56MP0005174_abnormal_tail_pigmentation1.06068501
57MP0005253_abnormal_eye_physiology1.02995276
58MP0005636_abnormal_mineral_homeostasis1.02864494
59MP0000427_abnormal_hair_cycle1.02119808
60MP0005075_abnormal_melanosome_morpholog1.00412097
61MP0009763_increased_sensitivity_to0.98606984
62MP0005551_abnormal_eye_electrophysiolog0.95596706
63MP0004215_abnormal_myocardial_fiber0.94861038
64MP0000604_amyloidosis0.93801995
65MP0002160_abnormal_reproductive_system0.93065413
66MP0006036_abnormal_mitochondrial_physio0.93026301
67MP0001835_abnormal_antigen_presentation0.92807514
68MP0004484_altered_response_of0.92258923
69MP0008469_abnormal_protein_level0.89723625
70MP0005164_abnormal_response_to0.89433280
71MP0003172_abnormal_lysosome_physiology0.89263392
72MP0009764_decreased_sensitivity_to0.88947039
73MP0009642_abnormal_blood_homeostasis0.87705118
74MP0005408_hypopigmentation0.86690356
75MP0001929_abnormal_gametogenesis0.85227956
76MP0005084_abnormal_gallbladder_morpholo0.83203877
77MP0001661_extended_life_span0.83097944
78MP0004782_abnormal_surfactant_physiolog0.79933306
79MP0002332_abnormal_exercise_endurance0.77551671
80MP0005503_abnormal_tendon_morphology0.76868589
81MP0005376_homeostasis/metabolism_phenot0.76372570
82MP0005220_abnormal_exocrine_pancreas0.74644404
83MP0002078_abnormal_glucose_homeostasis0.73669090
84MP0001727_abnormal_embryo_implantation0.73553779
85MP0005670_abnormal_white_adipose0.73368823
86MP0010234_abnormal_vibrissa_follicle0.73199592
87MP0005165_increased_susceptibility_to0.73136186
88MP0003698_abnormal_male_reproductive0.72832199
89MP0005334_abnormal_fat_pad0.71755945
90MP0000538_abnormal_urinary_bladder0.71747497
91MP0002971_abnormal_brown_adipose0.71425809
92MP0002132_abnormal_respiratory_system0.70598861
93MP0002095_abnormal_skin_pigmentation0.70086545
94MP0004130_abnormal_muscle_cell0.69393706
95MP0002254_reproductive_system_inflammat0.68148025
96MP0009765_abnormal_xenobiotic_induced0.66653488
97MP0009053_abnormal_anal_canal0.65366951
98MP0005266_abnormal_metabolism0.63405863
99MP0003690_abnormal_glial_cell0.63139158
100MP0003724_increased_susceptibility_to0.61548954
101MP0006035_abnormal_mitochondrial_morpho0.61358854
102MP0005464_abnormal_platelet_physiology0.61196121
103MP0005535_abnormal_body_temperature0.60904749
104MP0001756_abnormal_urination0.60661997
105MP0003638_abnormal_response/metabolism_0.57493048
106MP0009384_cardiac_valve_regurgitation0.56502745
107MP0005410_abnormal_fertilization0.54702616
108MP0003329_amyloid_beta_deposits0.53128217
109MP0000230_abnormal_systemic_arterial0.50193769
110MP0005448_abnormal_energy_balance0.49562292
111MP0008438_abnormal_cutaneous_collagen0.47259183
112MP0002837_dystrophic_cardiac_calcinosis0.46442923
113MP0002876_abnormal_thyroid_physiology0.45226001
114MP0003953_abnormal_hormone_level0.44663171
115MP0002136_abnormal_kidney_physiology0.43543300
116MP0005666_abnormal_adipose_tissue0.42456273
117MP0002822_catalepsy0.41739277
118MP0002295_abnormal_pulmonary_circulatio0.40265828
119MP0005395_other_phenotype0.39125193
120MP0002928_abnormal_bile_duct0.38551618
121MP0008873_increased_physiological_sensi0.38077959
122MP0000249_abnormal_blood_vessel0.37448832
123MP0001243_abnormal_dermal_layer0.35840849
124MP0005248_abnormal_Harderian_gland0.34377616
125MP0009672_abnormal_birth_weight0.33019821
126MP0008874_decreased_physiological_sensi0.32874709
127MP0005058_abnormal_lysosome_morphology0.31885872
128MP0005023_abnormal_wound_healing0.31650476
129MP0008872_abnormal_physiological_respon0.31270517
130MP0009115_abnormal_fat_cell0.30635191
131MP0001765_abnormal_ion_homeostasis0.30465891
132MP0002168_other_aberrant_phenotype0.29925714
133MP0005595_abnormal_vascular_smooth0.29894822
134MP0001881_abnormal_mammary_gland0.29782057
135MP0004381_abnormal_hair_follicle0.29408572
136MP0004883_abnormal_blood_vessel0.28049538
137MP0002909_abnormal_adrenal_gland0.27711878
138MP0002060_abnormal_skin_morphology0.27438478
139MP0003075_altered_response_to0.27373731
140MP0002970_abnormal_white_adipose0.26564574
141MP0003718_maternal_effect0.26097847
142MP0006082_CNS_inflammation0.25729817
143MP0000566_synostosis0.25363474

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)7.37910413
2Deep venous thrombosis (HP:0002625)7.22545099
3Intrahepatic cholestasis (HP:0001406)7.20829724
4Abnormality of monocarboxylic acid metabolism (HP:0010996)6.40917233
5Hypobetalipoproteinemia (HP:0003563)6.29772399
6Prolonged partial thromboplastin time (HP:0003645)6.27445119
7Xanthomatosis (HP:0000991)6.03029309
8Hyperlipoproteinemia (HP:0010980)5.25958789
9Complement deficiency (HP:0004431)5.23332640
10Hyperglycinemia (HP:0002154)4.60246915
11Hyperammonemia (HP:0001987)4.59105717
12Hypolipoproteinemia (HP:0010981)4.58914540
13Epidermoid cyst (HP:0200040)4.41617947
14Joint hemorrhage (HP:0005261)4.40225193
15Abnormality of the common coagulation pathway (HP:0010990)4.36268528
16Ketosis (HP:0001946)4.34139046
17Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.20862270
18Abnormality of methionine metabolism (HP:0010901)4.19810889
19Fat malabsorption (HP:0002630)4.09564916
20Hypoglycemic coma (HP:0001325)4.06843525
21Abnormality of sulfur amino acid metabolism (HP:0004339)3.99668705
22Abnormality of aspartate family amino acid metabolism (HP:0010899)3.99092472
23Abnormality of glycine metabolism (HP:0010895)3.96595606
24Abnormality of serine family amino acid metabolism (HP:0010894)3.96595606
25Abnormality of the intrinsic pathway (HP:0010989)3.94619284
26Hypoalphalipoproteinemia (HP:0003233)3.87552907
27Abnormality of glutamine family amino acid metabolism (HP:0010902)3.87461466
28Hyperglycinuria (HP:0003108)3.86597670
29Abnormality of complement system (HP:0005339)3.81365191
30Hypercholesterolemia (HP:0003124)3.56358158
31Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.55130683
32Abnormality of pyrimidine metabolism (HP:0004353)3.54731915
33Conjugated hyperbilirubinemia (HP:0002908)3.52849049
34Abnormality of fatty-acid metabolism (HP:0004359)3.44634155
35Delayed CNS myelination (HP:0002188)3.37287809
36Hyperbilirubinemia (HP:0002904)3.29723682
37Steatorrhea (HP:0002570)3.13743500
38Abnormality of serum amino acid levels (HP:0003112)3.10875981
39Ketoacidosis (HP:0001993)3.10416904
40Abnormality of vitamin B metabolism (HP:0004340)3.04860259
41Glycosuria (HP:0003076)2.96066124
42Abnormality of urine glucose concentration (HP:0011016)2.96066124
43Petechiae (HP:0000967)2.96035846
44Hepatocellular carcinoma (HP:0001402)2.95456230
45Abnormality of nucleobase metabolism (HP:0010932)2.92060138
46Methylmalonic acidemia (HP:0002912)2.86830738
47Congenital sensorineural hearing impairment (HP:0008527)2.86820080
48Spontaneous abortion (HP:0005268)2.78602630
49Metabolic acidosis (HP:0001942)2.76038665
50Abnormality of the vitamin B12 metabolism (HP:0004341)2.74037837
51Skin nodule (HP:0200036)2.72556446
52Abnormality of dicarboxylic acid metabolism (HP:0010995)2.72414323
53Dicarboxylic aciduria (HP:0003215)2.72414323
54Neonatal onset (HP:0003623)2.64172248
55Myocardial infarction (HP:0001658)2.64083342
56Abnormality of alanine metabolism (HP:0010916)2.62484138
57Hyperalaninemia (HP:0003348)2.62484138
58Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.62484138
59Abnormality of purine metabolism (HP:0004352)2.60724249
60Lethargy (HP:0001254)2.59906556
61Vascular calcification (HP:0004934)2.59712319
62Facial shape deformation (HP:0011334)2.59061947
63Potter facies (HP:0002009)2.59061947
64Systemic lupus erythematosus (HP:0002725)2.58159728
65Chronic hepatic failure (HP:0100626)2.55702021
66Hypoglycemic seizures (HP:0002173)2.52386156
67Cholecystitis (HP:0001082)2.51759552
68Abnormal gallbladder physiology (HP:0012438)2.51759552
69Hypochromic microcytic anemia (HP:0004840)2.48896048
70Abnormality of glycosphingolipid metabolism (HP:0004343)2.47713780
71Abnormality of glycolipid metabolism (HP:0010969)2.47713780
72Abnormality of liposaccharide metabolism (HP:0010968)2.47713780
73Mitral stenosis (HP:0001718)2.44376621
74Renal Fanconi syndrome (HP:0001994)2.43784812
75Cerebral edema (HP:0002181)2.43022778
76Gout (HP:0001997)2.38699080
77Abnormal gallbladder morphology (HP:0012437)2.37714471
78Spastic diplegia (HP:0001264)2.36843597
79Acanthocytosis (HP:0001927)2.36834186
80Cardiovascular calcification (HP:0011915)2.36030605
81Generalized aminoaciduria (HP:0002909)2.32058603
82Esophageal varix (HP:0002040)2.30984555
83Decreased circulating renin level (HP:0003351)2.29623735
84Cholelithiasis (HP:0001081)2.28868749
85Vacuolated lymphocytes (HP:0001922)2.28857394
86Methylmalonic aciduria (HP:0012120)2.27277176
87Abnormal spermatogenesis (HP:0008669)2.25998206
88Hyperinsulinemic hypoglycemia (HP:0000825)2.24345173
89Glomerulonephritis (HP:0000099)2.22806032
90Malnutrition (HP:0004395)2.22524792
91Irritability (HP:0000737)2.19540727
92Sensorimotor neuropathy (HP:0007141)2.18615056
93Exertional dyspnea (HP:0002875)2.18213956
94Amyloidosis (HP:0011034)2.17667725
95Hematochezia (HP:0002573)2.17659978
96Azoospermia (HP:0000027)2.14564560
97Pancreatitis (HP:0001733)2.13632471
98Increased mean platelet volume (HP:0011877)2.12794963
99Tubulointerstitial nephritis (HP:0001970)2.11677546
100Hypophosphatemic rickets (HP:0004912)2.11339877
101Vomiting (HP:0002013)2.10930950
102Brushfield spots (HP:0001088)2.07828951
103Enlarged kidneys (HP:0000105)2.07543904
104CNS demyelination (HP:0007305)2.07442486
105Hypothermia (HP:0002045)2.06818245
106Recurrent gram-negative bacterial infections (HP:0005420)2.06257214
107Thrombophlebitis (HP:0004418)2.05903720
108Widely patent fontanelles and sutures (HP:0004492)2.03425147
109Gingival bleeding (HP:0000225)2.02907287
110Wrist flexion contracture (HP:0001239)2.00015907
111Abnormal auditory evoked potentials (HP:0006958)2.00006990
112Late onset (HP:0003584)1.98826106
113Abnormality of the gallbladder (HP:0005264)1.98537709
114Opisthotonus (HP:0002179)1.97580820
115Bile duct proliferation (HP:0001408)1.97424420
116Abnormal biliary tract physiology (HP:0012439)1.97424420
117Menorrhagia (HP:0000132)1.96067598
118Hypoplasia of the fovea (HP:0007750)1.95118981
119Aplasia/Hypoplasia of the fovea (HP:0008060)1.95118981
120Renal cortical cysts (HP:0000803)1.95040780
121Conjunctival telangiectasia (HP:0000524)1.94748266
122Abnormality of the vasculature of the conjunctiva (HP:0008054)1.94264608
123Fair hair (HP:0002286)1.94063062
124Arthropathy (HP:0003040)1.93857896
125Attenuation of retinal blood vessels (HP:0007843)1.93183399
126Albinism (HP:0001022)1.92908889
127Abnormal cartilage morphology (HP:0002763)1.91969449
128Purpura (HP:0000979)1.91389507
129Abnormal platelet volume (HP:0011876)1.89016655
130Facial diplegia (HP:0001349)1.87457910
131Hemorrhage of the eye (HP:0011885)1.87224847
132Elevated hepatic transaminases (HP:0002910)1.85950038
133Abnormality of transition element cation homeostasis (HP:0011030)1.85375240
134Hyperphosphaturia (HP:0003109)1.82886067
135Abnormality of iron homeostasis (HP:0011031)1.80895903
136Prolonged bleeding time (HP:0003010)1.79238201
137Medial flaring of the eyebrow (HP:0010747)1.78740334
138Palpitations (HP:0001962)1.78584741
139Hepatic necrosis (HP:0002605)1.78251106
140Abnormality of polysaccharide metabolism (HP:0011012)1.76366986
141Abnormality of glycosaminoglycan metabolism (HP:0004371)1.76366986
142Abnormality of mucopolysaccharide metabolism (HP:0011020)1.76366986
143Abnormality of vitamin metabolism (HP:0100508)1.76210365
144Lipid accumulation in hepatocytes (HP:0006561)1.76112388
145Hydroxyprolinuria (HP:0003080)1.74671511
146Abnormality of proline metabolism (HP:0010907)1.74671511
147Respiratory distress (HP:0002098)1.74277327
148Poikilocytosis (HP:0004447)1.73400040
149Rickets (HP:0002748)1.73084511
150Abnormal enzyme/coenzyme activity (HP:0012379)1.70746243
151Hypertriglyceridemia (HP:0002155)1.68997775
152Pulmonary embolism (HP:0002204)1.67981145
153Hyperglycemia (HP:0003074)1.66128609
154Nephritis (HP:0000123)1.66047830

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK7.32132405
2FGFR44.45114374
3SIK13.67956092
4MST43.65726072
5INSRR3.59999619
6ERN13.52456849
7TAOK32.98899184
8TNIK2.85406696
9ERBB42.67498615
10MAP3K42.56085542
11BMPR1B2.53985377
12PIK3CG2.40385542
13FLT32.21372374
14PKN22.17302673
15PNCK2.02648784
16LATS11.85247498
17NEK91.78830466
18TRIB31.78148828
19MST1R1.69894551
20PDK41.69878669
21PDK31.69878669
22PLK41.66598011
23EIF2AK11.65341842
24MAP4K21.60120440
25KDR1.59120487
26TYK21.58261650
27PLK21.58008102
28MAP2K41.57762837
29MAP3K61.50257527
30PINK11.48603823
31BRSK21.44594661
32MAPK111.44136697
33FGFR21.38714054
34ERBB31.37840766
35PTK61.36079342
36ADRBK21.35378527
37GRK11.30514487
38ABL21.29518557
39MAP3K71.26084201
40BLK1.23177075
41NLK1.15032949
42CAMKK21.14106370
43NEK11.13386302
44PDGFRA1.11251265
45STK38L1.10988275
46MET1.10366484
47FER1.09821577
48TGFBR21.09391071
49WNK31.09350755
50TBK11.05872251
51OXSR11.01112467
52MAP2K70.96038911
53MAPK150.93387350
54PDK20.92278663
55JAK20.92088195
56PRKAA20.91931272
57TIE10.90276343
58DYRK1B0.86898778
59MAP3K120.86610275
60JAK10.86064417
61MAP2K60.85041270
62FGR0.84720722
63FGFR30.84442488
64FRK0.83580008
65CSNK1G10.83386476
66PLK30.83327057
67DDR20.82353855
68TEC0.82217547
69MELK0.82031252
70PRKCE0.81128447
71CAMK1D0.80399053
72DAPK20.78297455
73MYLK0.78205310
74ERBB20.78037262
75CSNK1G30.76744181
76MAP2K30.76467657
77BCR0.76383624
78GRK50.75337407
79TTK0.71911930
80LIMK10.70164050
81PRKACG0.69490182
82MAPK40.69077462
83PRKCZ0.69031958
84EPHB10.68002439
85CAMK2G0.67927002
86ICK0.67530911
87BMPR20.67229640
88ADRBK10.66830732
89MAP3K20.66769475
90TAF10.66664041
91VRK10.66431969
92CSK0.66336786
93BRAF0.65870113
94MAP3K50.65532973
95STK160.64312830
96CSF1R0.62513977
97IRAK40.61164825
98PIM20.60470088
99ZAP700.59331514
100SGK20.58558996
101IGF1R0.58481723
102CSNK1G20.57250594
103PTK20.56944904
104IKBKE0.56075406
105MAP3K30.55760186
106PRKCQ0.54017893
107ZAK0.53971768
108SRPK10.53884071
109EIF2AK30.53658748
110PRKG20.53486506
111MAPK120.50537551
112GSK3A0.50415947
113FGFR10.49158683
114PRKG10.48070810
115PAK30.47061574
116STK30.46153690
117KIT0.45931161
118CAMK1G0.45814412
119CDK60.44933449
120MAP3K140.44478507
121LYN0.43877359
122MAPK70.42583113
123TGFBR10.42325603
124CCNB10.41400845
125PIK3CA0.41285556
126TRIM280.39412774
127CLK10.39230804
128PDPK10.38975432
129PTK2B0.38012133
130ACVR1B0.37798366
131EGFR0.37634641
132SCYL20.37588401
133PRKAA10.37284247
134LMTK20.36481175
135MKNK20.36312174
136MAP2K10.36248532
137EPHA30.35888375
138IRAK10.35522373
139WEE10.35482173
140AKT30.34969808
141PDGFRB0.34605713
142PRKACB0.33427326
143ABL10.33032346
144PDK10.32815257
145RET0.31040562
146IKBKB0.30739926
147IRAK20.30101870
148PBK0.29754325
149CSNK1A1L0.29451201
150STK390.29304671
151PRKCG0.28434199
152NUAK10.28365460
153PRKCA0.27674851
154TXK0.27257576
155IRAK30.26848455
156RIPK10.26707245
157ITK0.26081292
158MAP3K110.25821453
159MAPKAPK30.25284758
160STK240.24707379

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.40047727
2Nitrogen metabolism_Homo sapiens_hsa009103.38135591
3Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.26998124
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.04255136
5Arginine biosynthesis_Homo sapiens_hsa002202.75046559
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.71230393
7Tryptophan metabolism_Homo sapiens_hsa003802.66428303
8Complement and coagulation cascades_Homo sapiens_hsa046102.63809880
9Fatty acid degradation_Homo sapiens_hsa000712.62149329
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.58413684
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.45672240
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.42672035
13Caffeine metabolism_Homo sapiens_hsa002322.26270981
14Steroid hormone biosynthesis_Homo sapiens_hsa001402.26075293
15Pentose and glucuronate interconversions_Homo sapiens_hsa000402.24415329
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.23764927
17Propanoate metabolism_Homo sapiens_hsa006402.16181119
18Peroxisome_Homo sapiens_hsa041462.09997809
19Chemical carcinogenesis_Homo sapiens_hsa052042.07110383
20Butanoate metabolism_Homo sapiens_hsa006502.02125777
21Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.02086627
22PPAR signaling pathway_Homo sapiens_hsa033201.93239225
23Fatty acid metabolism_Homo sapiens_hsa012121.92064634
24Histidine metabolism_Homo sapiens_hsa003401.86228243
25Drug metabolism - other enzymes_Homo sapiens_hsa009831.80545738
26Retinol metabolism_Homo sapiens_hsa008301.70890646
27beta-Alanine metabolism_Homo sapiens_hsa004101.65606036
28Selenocompound metabolism_Homo sapiens_hsa004501.64594631
29Protein export_Homo sapiens_hsa030601.61006672
30Staphylococcus aureus infection_Homo sapiens_hsa051501.59477553
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.57282609
32Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.56965989
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.55812993
34Tyrosine metabolism_Homo sapiens_hsa003501.54508631
35Pyruvate metabolism_Homo sapiens_hsa006201.53322981
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.52781314
37Sulfur metabolism_Homo sapiens_hsa009201.47958915
38Fatty acid elongation_Homo sapiens_hsa000621.46695431
39Phenylalanine metabolism_Homo sapiens_hsa003601.44830566
402-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.44026322
41Bile secretion_Homo sapiens_hsa049761.41396460
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.35147349
43Starch and sucrose metabolism_Homo sapiens_hsa005001.28996281
44Steroid biosynthesis_Homo sapiens_hsa001001.27115246
45Carbon metabolism_Homo sapiens_hsa012001.22249468
46Folate biosynthesis_Homo sapiens_hsa007901.20488518
47Biosynthesis of amino acids_Homo sapiens_hsa012301.18098570
48ABC transporters_Homo sapiens_hsa020101.13726129
49Fat digestion and absorption_Homo sapiens_hsa049751.13143118
50Sulfur relay system_Homo sapiens_hsa041221.06427487
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.00922832
52Vitamin B6 metabolism_Homo sapiens_hsa007500.98858359
53Maturity onset diabetes of the young_Homo sapiens_hsa049500.98676133
54Arginine and proline metabolism_Homo sapiens_hsa003300.98674686
55Sphingolipid metabolism_Homo sapiens_hsa006000.96126057
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.94844977
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.87678633
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.84060384
59Vitamin digestion and absorption_Homo sapiens_hsa049770.83307944
60Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.82466580
61Non-homologous end-joining_Homo sapiens_hsa034500.81226348
62Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.80679811
63Glutathione metabolism_Homo sapiens_hsa004800.80221613
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79939483
65Fatty acid biosynthesis_Homo sapiens_hsa000610.76158532
66Lysine degradation_Homo sapiens_hsa003100.74890930
67Collecting duct acid secretion_Homo sapiens_hsa049660.68312036
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.67031729
69Pentose phosphate pathway_Homo sapiens_hsa000300.66471009
70Glycerolipid metabolism_Homo sapiens_hsa005610.65625793
71One carbon pool by folate_Homo sapiens_hsa006700.64872259
72Oxidative phosphorylation_Homo sapiens_hsa001900.60233474
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59950833
74Type I diabetes mellitus_Homo sapiens_hsa049400.56585889
75Lysosome_Homo sapiens_hsa041420.53862875
76Circadian rhythm_Homo sapiens_hsa047100.52504041
77Metabolic pathways_Homo sapiens_hsa011000.50293731
78Phagosome_Homo sapiens_hsa041450.45710202
79Regulation of autophagy_Homo sapiens_hsa041400.44568582
80Other glycan degradation_Homo sapiens_hsa005110.42655930
81Pertussis_Homo sapiens_hsa051330.41685269
82Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.37655645
83Protein digestion and absorption_Homo sapiens_hsa049740.35739153
84Prion diseases_Homo sapiens_hsa050200.35670581
85Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.34721002
86Serotonergic synapse_Homo sapiens_hsa047260.34620065
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.34071038
88Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.31922381
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.31720695
90Galactose metabolism_Homo sapiens_hsa000520.28956182
91Linoleic acid metabolism_Homo sapiens_hsa005910.28607250
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.26668710
93N-Glycan biosynthesis_Homo sapiens_hsa005100.26079369
94Rheumatoid arthritis_Homo sapiens_hsa053230.25559690
95Fructose and mannose metabolism_Homo sapiens_hsa000510.24729223
96Legionellosis_Homo sapiens_hsa051340.24652687
97Graft-versus-host disease_Homo sapiens_hsa053320.22142615
98Insulin resistance_Homo sapiens_hsa049310.21763532
99Ovarian steroidogenesis_Homo sapiens_hsa049130.21716233
100Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.21553667
101Proteasome_Homo sapiens_hsa030500.20460471
102Parkinsons disease_Homo sapiens_hsa050120.20418936
103Renin secretion_Homo sapiens_hsa049240.19959547
104Basal transcription factors_Homo sapiens_hsa030220.17361332
105Glucagon signaling pathway_Homo sapiens_hsa049220.14206881
106Glycerophospholipid metabolism_Homo sapiens_hsa005640.11443375
107Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.01070891
108African trypanosomiasis_Homo sapiens_hsa05143-0.2454469
109Mineral absorption_Homo sapiens_hsa04978-0.2446708
110Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.2430409
111Amoebiasis_Homo sapiens_hsa05146-0.2286101
112Pyrimidine metabolism_Homo sapiens_hsa00240-0.2212360
113Longevity regulating pathway - multiple species_Homo sapiens_hsa04213-0.2155720
114Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.2153928
115Hepatitis C_Homo sapiens_hsa05160-0.1958578
116Ether lipid metabolism_Homo sapiens_hsa00565-0.1868670
117Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1816345
118Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1812458
119Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1422628
120Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1411598
121Insulin signaling pathway_Homo sapiens_hsa04910-0.1304610
122Renin-angiotensin system_Homo sapiens_hsa04614-0.1081607
123Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.0938172
124Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0918800
125Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.0490622
126Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.0042671
127AMPK signaling pathway_Homo sapiens_hsa04152-0.0011701

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