RMND5B

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)9.58513728
2DNA deamination (GO:0045006)8.02189225
3transcription from mitochondrial promoter (GO:0006390)8.01930589
4replication fork processing (GO:0031297)7.09798247
5proline metabolic process (GO:0006560)7.02197678
6embryonic process involved in female pregnancy (GO:0060136)6.55782622
7maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)6.10491161
8positive regulation of protein homooligomerization (GO:0032464)5.91964690
9rRNA modification (GO:0000154)5.68586563
10formation of translation preinitiation complex (GO:0001731)5.31705760
11viral mRNA export from host cell nucleus (GO:0046784)5.30371086
12somatic diversification of immune receptors via somatic mutation (GO:0002566)5.29788416
13somatic hypermutation of immunoglobulin genes (GO:0016446)5.29788416
14mitochondrial DNA metabolic process (GO:0032042)5.25097227
15regulation of integrin activation (GO:0033623)5.09427133
16oxidative demethylation (GO:0070989)5.05329804
17mitotic G1 DNA damage checkpoint (GO:0031571)5.02847007
18regulation of protein homooligomerization (GO:0032462)5.01858391
19establishment of apical/basal cell polarity (GO:0035089)4.94551034
20establishment of protein localization to mitochondrial membrane (GO:0090151)4.78421522
21poly(A)+ mRNA export from nucleus (GO:0016973)4.72007951
22DNA strand renaturation (GO:0000733)4.67981903
23DNA replication checkpoint (GO:0000076)4.65596582
24ribosomal small subunit biogenesis (GO:0042274)4.63199088
25mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.48850999
26negative regulation of JAK-STAT cascade (GO:0046426)4.45556929
27mitotic G1/S transition checkpoint (GO:0044819)4.44738001
28G1 DNA damage checkpoint (GO:0044783)4.44578872
29rRNA methylation (GO:0031167)4.43822454
30mRNA cleavage (GO:0006379)4.43474180
31telomere maintenance via semi-conservative replication (GO:0032201)4.43308278
32establishment or maintenance of monopolar cell polarity (GO:0061339)4.30158079
33establishment of monopolar cell polarity (GO:0061162)4.30158079
34mitochondrial RNA metabolic process (GO:0000959)4.08065083
35base-excision repair (GO:0006284)4.07742074
36GDP-mannose metabolic process (GO:0019673)4.01463106
37viral transcription (GO:0019083)3.98662126
38regulation of translational fidelity (GO:0006450)3.97255385
39energy coupled proton transport, down electrochemical gradient (GO:0015985)3.89678279
40ATP synthesis coupled proton transport (GO:0015986)3.89678279
41negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.89378751
42nucleotide-excision repair, DNA gap filling (GO:0006297)3.88137694
43maturation of 5.8S rRNA (GO:0000460)3.85598289
44translational termination (GO:0006415)3.81696306
45pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.75809817
46transcription elongation from RNA polymerase III promoter (GO:0006385)3.74773596
47termination of RNA polymerase III transcription (GO:0006386)3.74773596
48regulation of double-strand break repair via homologous recombination (GO:0010569)3.73423581
49mitochondrial respiratory chain complex assembly (GO:0033108)3.71448172
50DNA strand elongation involved in DNA replication (GO:0006271)3.70165173
51water-soluble vitamin biosynthetic process (GO:0042364)3.66303196
52embryonic placenta development (GO:0001892)3.66154574
53peptidyl-histidine modification (GO:0018202)3.63250959
54base-excision repair, AP site formation (GO:0006285)3.61383737
55cellular response to ATP (GO:0071318)3.61274805
56telomere maintenance via recombination (GO:0000722)3.60968563
57double-strand break repair via nonhomologous end joining (GO:0006303)3.60652731
58non-recombinational repair (GO:0000726)3.60652731
59peptidyl-arginine omega-N-methylation (GO:0035247)3.58472296
60translational elongation (GO:0006414)3.57972207
61protein complex biogenesis (GO:0070271)3.57446381
62cellular response to zinc ion (GO:0071294)3.54739223
63DNA integration (GO:0015074)3.52816050
64termination of RNA polymerase II transcription (GO:0006369)3.51605099
65DNA strand elongation (GO:0022616)3.47043852
66ribonucleoprotein complex biogenesis (GO:0022613)3.47036206
67mitochondrial respiratory chain complex I assembly (GO:0032981)3.46540546
68NADH dehydrogenase complex assembly (GO:0010257)3.46540546
69mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.46540546
70regulation of mitochondrial translation (GO:0070129)3.46033091
71spliceosomal tri-snRNP complex assembly (GO:0000244)3.44634385
72ribosome biogenesis (GO:0042254)3.43977891
73positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.42959628
74positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.42959628
75positive regulation of mitotic sister chromatid separation (GO:1901970)3.42959628
76negative regulation of cell cycle arrest (GO:0071157)3.42089691
77DNA double-strand break processing (GO:0000729)3.41363181
78negative regulation of protein oligomerization (GO:0032460)3.40330693
79glutamine family amino acid biosynthetic process (GO:0009084)3.39952732
80histone H4-K12 acetylation (GO:0043983)3.34896151
81dosage compensation (GO:0007549)3.34438065
82positive regulation of developmental pigmentation (GO:0048087)3.34384953
83positive regulation of protein oligomerization (GO:0032461)3.34299122
84regulation of RNA export from nucleus (GO:0046831)3.32950423
85negative regulation of mRNA processing (GO:0050686)3.32896255
86cellular component biogenesis (GO:0044085)3.30122834
87negative regulation of Ras GTPase activity (GO:0034261)3.28736530
88trophectodermal cell differentiation (GO:0001829)3.28437651
89folic acid metabolic process (GO:0046655)3.28165422
90tRNA modification (GO:0006400)3.28102012
91spliceosomal snRNP assembly (GO:0000387)3.27645680
92maturation of SSU-rRNA (GO:0030490)3.27436011
93meiotic chromosome segregation (GO:0045132)3.26764802
94histone arginine methylation (GO:0034969)3.26752147
95rRNA metabolic process (GO:0016072)3.25887102
96negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.21729069
97pyrimidine nucleotide catabolic process (GO:0006244)3.20498346
98mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.19924086
99regulation of protein oligomerization (GO:0032459)3.19176778
100mitochondrial DNA replication (GO:0006264)3.19069225
101nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.16906879
102cullin deneddylation (GO:0010388)3.16534287
103proteasome assembly (GO:0043248)3.16320941
104ribosomal large subunit biogenesis (GO:0042273)3.16221600
105electron transport chain (GO:0022900)3.16108485
106regulation of sister chromatid cohesion (GO:0007063)3.12228218
107respiratory electron transport chain (GO:0022904)3.11605359
108positive regulation of chromosome segregation (GO:0051984)3.11352949
109negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.11204585
110translation (GO:0006412)3.10794631
111viral life cycle (GO:0019058)3.08746857
112SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.08390692
113negative regulation of RNA splicing (GO:0033119)3.07498339
114regulation of nuclear cell cycle DNA replication (GO:0033262)3.05786686
115telomere maintenance via telomere lengthening (GO:0010833)3.05325576
116pseudouridine synthesis (GO:0001522)3.03682376
117positive regulation by host of viral transcription (GO:0043923)3.02992787
118positive regulation of DNA repair (GO:0045739)3.02763888
119translational initiation (GO:0006413)3.01799210
120labyrinthine layer development (GO:0060711)3.01704185
121cotranslational protein targeting to membrane (GO:0006613)3.01074278
122mitotic recombination (GO:0006312)3.00576349
123regulation of double-strand break repair (GO:2000779)3.00399265
124negative regulation of fatty acid biosynthetic process (GO:0045717)3.00293654
125DNA topological change (GO:0006265)2.99859309
126protein targeting to ER (GO:0045047)2.98973574
127nodal signaling pathway (GO:0038092)2.98852894
128resolution of meiotic recombination intermediates (GO:0000712)2.96706875
129cellular protein complex disassembly (GO:0043624)2.96457740
130regulation of DNA damage checkpoint (GO:2000001)2.95383713
131negative regulation of DNA-templated transcription, elongation (GO:0032785)2.94928277
132ncRNA processing (GO:0034470)2.94281577
133protein deneddylation (GO:0000338)2.94149160
134peptidyl-arginine methylation (GO:0018216)2.93586523
135peptidyl-arginine N-methylation (GO:0035246)2.93586523
136metallo-sulfur cluster assembly (GO:0031163)2.93211289
137iron-sulfur cluster assembly (GO:0016226)2.93211289
138respiratory chain complex IV assembly (GO:0008535)2.91862963
139cytochrome complex assembly (GO:0017004)2.90667660
140DNA ligation (GO:0006266)2.89263474
141protein targeting to mitochondrion (GO:0006626)2.88541540
142tRNA processing (GO:0008033)2.88480003
143mRNA export from nucleus (GO:0006406)2.88010607
144DNA demethylation (GO:0080111)2.87742056
145kinetochore assembly (GO:0051382)2.85836830
146mitotic sister chromatid segregation (GO:0000070)2.83423746
147embryonic camera-type eye development (GO:0031076)2.82031462
148protein localization to endoplasmic reticulum (GO:0070972)2.81462317
149DNA replication-dependent nucleosome organization (GO:0034723)2.80544317
150DNA replication-dependent nucleosome assembly (GO:0006335)2.80544317
151face development (GO:0060324)2.80095890
152regulation of posttranscriptional gene silencing (GO:0060147)2.79943136
153regulation of gene silencing by miRNA (GO:0060964)2.79943136
154regulation of gene silencing by RNA (GO:0060966)2.79943136
155chaperone-mediated protein transport (GO:0072321)2.79770363
156ncRNA 3-end processing (GO:0043628)2.79508651
157establishment of protein localization to endoplasmic reticulum (GO:0072599)2.79377547
158activation of Rac GTPase activity (GO:0032863)2.79362384
159nucleoside transmembrane transport (GO:1901642)2.79042014
160mitochondrion morphogenesis (GO:0070584)2.77980209
161single strand break repair (GO:0000012)2.77385495
162protein complex disassembly (GO:0043241)2.76110339
163rRNA transcription (GO:0009303)2.75933455
164rRNA processing (GO:0006364)2.75923164
165ncRNA metabolic process (GO:0034660)2.73860960
166pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.72564633
167establishment of protein localization to mitochondrion (GO:0072655)2.70807121
168oxidative phosphorylation (GO:0006119)2.69492236
169UTP biosynthetic process (GO:0006228)2.69466844
170pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.68910925
171regulation of cell proliferation involved in kidney development (GO:1901722)2.66458567
172positive regulation of keratinocyte differentiation (GO:0045618)2.65056567
173CTP biosynthetic process (GO:0006241)2.62117284
174CTP metabolic process (GO:0046036)2.62117284
175macromolecular complex disassembly (GO:0032984)2.62085786
176RNA modification (GO:0009451)2.60945824
177tRNA methylation (GO:0030488)2.59826184
178L-serine metabolic process (GO:0006563)2.59430770
179protein localization to mitochondrion (GO:0070585)2.56531634
180tRNA metabolic process (GO:0006399)2.56282062
181ribonucleoside triphosphate biosynthetic process (GO:0009201)2.54913794

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse3.42651419
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.22620797
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.02888360
4E2F7_22180533_ChIP-Seq_HELA_Human3.01676262
5* SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.87655117
6MYC_19079543_ChIP-ChIP_MESCs_Mouse2.66310749
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.60571936
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.59251333
9KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.57017030
10KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.57017030
11KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.57017030
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.46040566
13ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.41028896
14SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.37893473
15VDR_21846776_ChIP-Seq_THP-1_Human2.33312455
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.24137392
17STAT6_21828071_ChIP-Seq_BEAS2B_Human2.19489611
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.10379407
19* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human2.09434924
20MYC_22102868_ChIP-Seq_BL_Human2.03492032
21* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.99748643
22* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.98598744
23POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.95241462
24E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.95094945
25STAT3_1855785_ChIP-Seq_MESCs_Mouse1.92322417
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.89482557
27NANOG_18555785_ChIP-Seq_MESCs_Mouse1.86771060
28PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.86430671
29FOXM1_23109430_ChIP-Seq_U2OS_Human1.83059515
30NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.81372948
31SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.76864124
32ZNF263_19887448_ChIP-Seq_K562_Human1.74804297
33PU.1_20513432_ChIP-Seq_Bcells_Mouse1.74595858
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.74368606
35E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74248495
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.73423509
37* GABP_19822575_ChIP-Seq_HepG2_Human1.71983908
38ESR1_15608294_ChIP-ChIP_MCF-7_Human1.69051515
39* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.67964241
40RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.67631664
41POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.66741082
42CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.64455798
43* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.64179184
44* P68_20966046_ChIP-Seq_HELA_Human1.63221305
45MYCN_18555785_ChIP-Seq_MESCs_Mouse1.63213600
46KLF4_18555785_ChIP-Seq_MESCs_Mouse1.61239943
47FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.61174074
48LXR_22292898_ChIP-Seq_THP-1_Human1.59145474
49MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58873557
50POU5F1_16518401_ChIP-PET_MESCs_Mouse1.57563838
51CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.56427697
52NELFA_20434984_ChIP-Seq_ESCs_Mouse1.54549155
53DCP1A_22483619_ChIP-Seq_HELA_Human1.53756684
54HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.53712585
55XRN2_22483619_ChIP-Seq_HELA_Human1.51807993
56TCF3_18692474_ChIP-Seq_MESCs_Mouse1.50038458
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.49943150
58CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.49897720
59GABP_17652178_ChIP-ChIP_JURKAT_Human1.48912844
60* FOXP1_21924763_ChIP-Seq_HESCs_Human1.47745980
61TET1_21451524_ChIP-Seq_MESCs_Mouse1.46783357
62* NANOG_21062744_ChIP-ChIP_HESCs_Human1.45678629
63EST1_17652178_ChIP-ChIP_JURKAT_Human1.44118795
64CIITA_25753668_ChIP-Seq_RAJI_Human1.40937414
65VDR_23849224_ChIP-Seq_CD4+_Human1.40731780
66BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.39927354
67E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.39034841
68E2F4_17652178_ChIP-ChIP_JURKAT_Human1.37781113
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.37549218
70TCF3_18692474_ChIP-Seq_MEFs_Mouse1.36876832
71FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.34687829
72CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.33760506
73TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.31699788
74KDM5A_27292631_Chip-Seq_BREAST_Human1.31091963
75SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.30767379
76POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.30277638
77PKCTHETA_26484144_Chip-Seq_BREAST_Human1.30151262
78SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.28632275
79* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.28501326
80YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28444464
81ZFX_18555785_ChIP-Seq_MESCs_Mouse1.27143028
82TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26564057
83SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.26365668
84CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.25579709
85* PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.25468579
86MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.25083577
87* E2F1_20622854_ChIP-Seq_HELA_Human1.24907030
88CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.24474756
89* TTF2_22483619_ChIP-Seq_HELA_Human1.23576450
90TDRD3_21172665_ChIP-Seq_MCF-7_Human1.23508579
91CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.22244372
92ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.21674265
93MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.21239672
94ETS1_21867929_ChIP-Seq_TH2_Mouse1.20618364
95* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.20027423
96* PHF8_20622854_ChIP-Seq_HELA_Human1.19972236
97NOTCH1_21737748_ChIP-Seq_TLL_Human1.19134259
98* POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.17918901
99NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.17602745
100RARB_24833708_ChIP-Seq_LIVER_Mouse1.15600043
101* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.15104201
102CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.15020926
103ERG_21242973_ChIP-ChIP_JURKAT_Human1.13915836
104SRY_22984422_ChIP-ChIP_TESTIS_Rat1.13149169
105PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12763414
106ELF1_20517297_ChIP-Seq_JURKAT_Human1.12374242
107ESR1_21235772_ChIP-Seq_MCF-7_Human1.12050095
108CREB1_15753290_ChIP-ChIP_HEK293T_Human1.11213881
109BCL6_27268052_Chip-Seq_Bcells_Human1.10985996
110ERA_21632823_ChIP-Seq_H3396_Human1.10556246
111SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.10515894
112CTCF_26484167_Chip-Seq_Bcells_Mouse1.09704862
113YY1_22570637_ChIP-Seq_MALME-3M_Human1.09537387
114SOX2_18692474_ChIP-Seq_MEFs_Mouse1.09464973
115OCT4_18692474_ChIP-Seq_MEFs_Mouse1.09428088
116SOX2_18692474_ChIP-Seq_MESCs_Mouse1.08984824
117KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.08346684
118RACK7_27058665_Chip-Seq_MCF-7_Human1.07528231
119RXRA_24833708_ChIP-Seq_LIVER_Mouse1.07488383
120KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.07475916
121CTCF_21964334_ChIP-Seq_BJAB-B_Human1.06159510
122PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.05986472
123DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.05849373
124SMC4_20622854_ChIP-Seq_HELA_Human1.05557695
125RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.05377483
126PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04912047
127FOXP3_21729870_ChIP-Seq_TREG_Human1.04897263
128KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.04606724
129BCOR_27268052_Chip-Seq_Bcells_Human1.04201251
130FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.03905740
131ELK3_25401928_ChIP-Seq_HUVEC_Human1.03682810
132E2F1_21310950_ChIP-Seq_MCF-7_Human1.03568225
133NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.03224667
134SRF_21415370_ChIP-Seq_HL-1_Mouse1.02978211
135EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.02933532
136* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02887272
137GATA1_22383799_ChIP-Seq_G1ME_Mouse1.02597826
138CTCF_21964334_Chip-Seq_Bcells_Human1.02552706
139KDM2B_26808549_Chip-Seq_DND41_Human1.02175926
140RARA_24833708_ChIP-Seq_LIVER_Mouse1.01425343
141* ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.01291911
142ESR2_21235772_ChIP-Seq_MCF-7_Human1.00010250
143MAF_26560356_Chip-Seq_TH2_Human0.97485289
144ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.96760794
145SA1_27219007_Chip-Seq_ERYTHROID_Human0.96604714
146* RUNX1_27514584_Chip-Seq_MCF-7_Human0.95793204

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication6.28008131
2MP0009278_abnormal_bone_marrow4.40753754
3MP0005171_absent_coat_pigmentation3.23549873
4MP0010094_abnormal_chromosome_stability3.23343580
5MP0002009_preneoplasia3.23054764
6MP0004233_abnormal_muscle_weight2.98489569
7MP0001545_abnormal_hematopoietic_system2.87050481
8MP0005397_hematopoietic_system_phenotyp2.87050481
9MP0004957_abnormal_blastocyst_morpholog2.86708830
10MP0003693_abnormal_embryo_hatching2.67881712
11MP0003136_yellow_coat_color2.67288068
12MP0005423_abnormal_somatic_nervous2.64153280
13MP0003111_abnormal_nucleus_morphology2.61151933
14MP0003786_premature_aging2.58022699
15MP0010030_abnormal_orbit_morphology2.54925801
16MP0001968_abnormal_touch/_nociception2.54715425
17MP0008058_abnormal_DNA_repair2.51557661
18MP0008995_early_reproductive_senescence2.46950849
19MP0002736_abnormal_nociception_after2.45670722
20MP0002653_abnormal_ependyma_morphology2.38116981
21MP0005083_abnormal_biliary_tract2.30808263
22MP0003806_abnormal_nucleotide_metabolis2.21434554
23MP0008877_abnormal_DNA_methylation2.18010842
24MP0005174_abnormal_tail_pigmentation2.15633355
25MP0004381_abnormal_hair_follicle2.06261774
26MP0003077_abnormal_cell_cycle1.98503799
27MP0005075_abnormal_melanosome_morpholog1.97224715
28MP0000678_abnormal_parathyroid_gland1.87217135
29MP0002160_abnormal_reproductive_system1.83551942
30MP0004133_heterotaxia1.82296009
31MP0002822_catalepsy1.81525781
32MP0006072_abnormal_retinal_apoptosis1.80637267
33MP0006036_abnormal_mitochondrial_physio1.76044700
34MP0000490_abnormal_crypts_of1.74855916
35MP0001188_hyperpigmentation1.73858279
36MP0003890_abnormal_embryonic-extraembry1.71941610
37MP0001697_abnormal_embryo_size1.65578121
38MP0008932_abnormal_embryonic_tissue1.65043431
39MP0003119_abnormal_digestive_system1.64070139
40MP0002086_abnormal_extraembryonic_tissu1.63071622
41MP0003172_abnormal_lysosome_physiology1.60847194
42MP0000015_abnormal_ear_pigmentation1.59593253
43MP0003283_abnormal_digestive_organ1.57324487
44MP0001986_abnormal_taste_sensitivity1.52600126
45MP0009333_abnormal_splenocyte_physiolog1.48865196
46MP0002084_abnormal_developmental_patter1.48531640
47MP0003718_maternal_effect1.45673208
48MP0003567_abnormal_fetal_cardiomyocyte1.45506872
49MP0001730_embryonic_growth_arrest1.41001191
50MP0000350_abnormal_cell_proliferation1.40810860
51MP0008872_abnormal_physiological_respon1.39501685
52MP0000371_diluted_coat_color1.39428610
53MP0002396_abnormal_hematopoietic_system1.38913318
54MP0002085_abnormal_embryonic_tissue1.38621825
55MP0001873_stomach_inflammation1.38027158
56MP0005451_abnormal_body_composition1.37828441
57MP0005380_embryogenesis_phenotype1.37297573
58MP0001672_abnormal_embryogenesis/_devel1.37297573
59MP0006035_abnormal_mitochondrial_morpho1.37125717
60MP0002638_abnormal_pupillary_reflex1.36937804
61MP0001293_anophthalmia1.35363907
62MP0010352_gastrointestinal_tract_polyps1.34289223
63MP0000685_abnormal_immune_system1.33748792
64MP0003453_abnormal_keratinocyte_physiol1.30001112
65MP0002019_abnormal_tumor_incidence1.28548275
66MP0000538_abnormal_urinary_bladder1.21542355
67MP0002080_prenatal_lethality1.21254839
68MP0000049_abnormal_middle_ear1.21098962
69MP0008875_abnormal_xenobiotic_pharmacok1.19952388
70MP0002269_muscular_atrophy1.19546400
71MP0005076_abnormal_cell_differentiation1.18714492
72MP0004197_abnormal_fetal_growth/weight/1.16943742
73MP0002234_abnormal_pharynx_morphology1.16278910
74MP0001919_abnormal_reproductive_system1.14163303
75MP0000639_abnormal_adrenal_gland1.12983978
76MP0002282_abnormal_trachea_morphology1.12179256
77MP0010307_abnormal_tumor_latency1.11719577
78MP0000689_abnormal_spleen_morphology1.09473454
79MP0002098_abnormal_vibrissa_morphology1.08558473
80MP0003984_embryonic_growth_retardation1.08490717
81MP0001346_abnormal_lacrimal_gland1.07611331
82MP0000313_abnormal_cell_death1.07170531
83MP0005058_abnormal_lysosome_morphology1.06991148
84MP0003763_abnormal_thymus_physiology1.05280222
85MP0000470_abnormal_stomach_morphology1.05143315
86MP0002249_abnormal_larynx_morphology1.02309606
87MP0003646_muscle_fatigue1.02172572
88MP0002088_abnormal_embryonic_growth/wei1.02146637
89MP0002938_white_spotting1.02041702
90MP0004782_abnormal_surfactant_physiolog1.01880212
91MP0003656_abnormal_erythrocyte_physiolo1.01554446
92MP0001145_abnormal_male_reproductive1.00544112
93MP0001529_abnormal_vocalization0.98857139
94MP0004264_abnormal_extraembryonic_tissu0.98718438
95MP0002405_respiratory_system_inflammati0.98182231
96MP0003828_pulmonary_edema0.97977592
97MP0008007_abnormal_cellular_replicative0.96382482
98MP0006292_abnormal_olfactory_placode0.95792834
99MP0000750_abnormal_muscle_regeneration0.94581190
100MP0005389_reproductive_system_phenotype0.93089309
101MP0002166_altered_tumor_susceptibility0.92325736
102MP0004147_increased_porphyrin_level0.91565933
103MP0005266_abnormal_metabolism0.90692163
104MP0002398_abnormal_bone_marrow0.90219390
105MP0009672_abnormal_birth_weight0.89941467
106MP0000427_abnormal_hair_cycle0.89705135
107MP0004145_abnormal_muscle_electrophysio0.89304798
108MP0002254_reproductive_system_inflammat0.89246618
109MP0002075_abnormal_coat/hair_pigmentati0.88021038
110MP0004185_abnormal_adipocyte_glucose0.87505241
111MP0000383_abnormal_hair_follicle0.87455340
112MP0003137_abnormal_impulse_conducting0.87305030
113MP0002751_abnormal_autonomic_nervous0.86628047
114MP0001929_abnormal_gametogenesis0.86344268
115MP0002722_abnormal_immune_system0.85908965
116MP0002210_abnormal_sex_determination0.84387650
117MP0000579_abnormal_nail_morphology0.83098712
118MP0001881_abnormal_mammary_gland0.82624657
119MP0003698_abnormal_male_reproductive0.82547904
120MP0002089_abnormal_postnatal_growth/wei0.82433910
121MP0005646_abnormal_pituitary_gland0.82188411
122MP0000703_abnormal_thymus_morphology0.80308502
123MP0001756_abnormal_urination0.80151320
124MP0005377_hearing/vestibular/ear_phenot0.79515745
125MP0003878_abnormal_ear_physiology0.79515745
126MP0010771_integument_phenotype0.78420724
127MP0003942_abnormal_urinary_system0.77653841
128MP0009115_abnormal_fat_cell0.76726951
129MP0003186_abnormal_redox_activity0.75740878
130MP0005410_abnormal_fertilization0.75504351
131MP0001764_abnormal_homeostasis0.73876281
132MP0000653_abnormal_sex_gland0.73869212
133MP0002796_impaired_skin_barrier0.73493211
134MP0005332_abnormal_amino_acid0.71875745
135MP0000566_synostosis0.71219939
136MP0002111_abnormal_tail_morphology0.71156537
137MP0001186_pigmentation_phenotype0.71123381
138MP0002006_tumorigenesis0.70464757
139MP0002132_abnormal_respiratory_system0.69638927
140MP0003938_abnormal_ear_development0.68792738
141MP0001324_abnormal_eye_pigmentation0.68779602
142MP0006082_CNS_inflammation0.68767407
143MP0000477_abnormal_intestine_morphology0.66517022
144MP0002277_abnormal_respiratory_mucosa0.64361210
145MP0001340_abnormal_eyelid_morphology0.64263721
146MP0005501_abnormal_skin_physiology0.64168502
147MP0005645_abnormal_hypothalamus_physiol0.64143378
148MP0001905_abnormal_dopamine_level0.64004452
149MP0000467_abnormal_esophagus_morphology0.63915965
150MP0002161_abnormal_fertility/fecundity0.61114516
151MP0003866_abnormal_defecation0.60411361
152MP0000358_abnormal_cell_content/0.60023338
153MP0002429_abnormal_blood_cell0.59673805
154MP0000462_abnormal_digestive_system0.59324443
155MP0002114_abnormal_axial_skeleton0.59026707
156MP0003699_abnormal_female_reproductive0.58057942
157MP0002970_abnormal_white_adipose0.57797561
158MP0002332_abnormal_exercise_endurance0.57544716
159MP0010155_abnormal_intestine_physiology0.57197429

Predicted human phenotypes

RankGene SetZ-score
1Pustule (HP:0200039)5.52507484
2Poikiloderma (HP:0001029)5.22560655
3Annular pancreas (HP:0001734)5.14121515
4Concave nail (HP:0001598)4.95408075
5Testicular atrophy (HP:0000029)4.79601162
6Facial hemangioma (HP:0000329)4.73413224
7Aplasia/Hypoplasia involving the carpal bones (HP:0006502)4.65812422
8Rib fusion (HP:0000902)4.65509294
9Increased IgM level (HP:0003496)4.58783167
10Rectovaginal fistula (HP:0000143)4.30848741
11Rectal fistula (HP:0100590)4.30848741
12Alopecia of scalp (HP:0002293)4.21429187
13Tongue fasciculations (HP:0001308)3.96085350
14Intestinal fistula (HP:0100819)3.90222650
15Vaginal fistula (HP:0004320)3.84009738
16Albinism (HP:0001022)3.75996216
17Male infertility (HP:0003251)3.74608430
18Muscle fibrillation (HP:0010546)3.61690248
19Decreased activity of mitochondrial respiratory chain (HP:0008972)3.56005139
20Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.56005139
21Abnormality of male internal genitalia (HP:0000022)3.54034522
22Mitochondrial inheritance (HP:0001427)3.49560213
23Basal cell carcinoma (HP:0002671)3.46584858
24Dysautonomia (HP:0002459)3.45814663
25Aplasia/hypoplasia of the humerus (HP:0006507)3.42453682
26Short humerus (HP:0005792)3.41009813
27Ulnar bowing (HP:0003031)3.39749777
28Abnormal mitochondria in muscle tissue (HP:0008316)3.38724757
29Squamous cell carcinoma (HP:0002860)3.33896287
30Absent radius (HP:0003974)3.32555339
31Absent thumb (HP:0009777)3.31951931
32Orthostatic hypotension (HP:0001278)3.30629952
33Septate vagina (HP:0001153)3.30591486
34Acute necrotizing encephalopathy (HP:0006965)3.30576227
35Hepatocellular necrosis (HP:0001404)3.29201980
36Hypochromic microcytic anemia (HP:0004840)3.28371979
37Intestinal atresia (HP:0011100)3.23819961
38Increased CSF lactate (HP:0002490)3.19940242
39Patellar aplasia (HP:0006443)3.15826432
40Aplasia involving forearm bones (HP:0009822)3.14607989
41Absent forearm bone (HP:0003953)3.14607989
42Turricephaly (HP:0000262)3.09354764
43Acute encephalopathy (HP:0006846)3.07727101
44Short chin (HP:0000331)3.06964064
45Abnormal hemoglobin (HP:0011902)3.05136798
46Hepatic necrosis (HP:0002605)3.04914351
47Selective tooth agenesis (HP:0001592)3.04055720
48Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.04020555
49Hypoplasia of the pons (HP:0012110)2.95161419
50Aplasia/Hypoplasia of the patella (HP:0006498)2.94268425
51Polycythemia (HP:0001901)2.91978595
52Congenital hip dislocation (HP:0001374)2.90244948
53Muscle fiber atrophy (HP:0100295)2.88588990
54Capillary hemangiomas (HP:0005306)2.88224485
55Chromosomal breakage induced by crosslinking agents (HP:0003221)2.87035572
56Progressive muscle weakness (HP:0003323)2.85688302
57Chromsome breakage (HP:0040012)2.85180663
58Premature graying of hair (HP:0002216)2.82582492
59Vertebral hypoplasia (HP:0008417)2.77737837
60Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.77737837
61Increased serum lactate (HP:0002151)2.74485021
62Anteriorly placed anus (HP:0001545)2.72942072
63Type 2 muscle fiber atrophy (HP:0003554)2.71593650
64Lipid accumulation in hepatocytes (HP:0006561)2.70428643
65Increased hepatocellular lipid droplets (HP:0006565)2.68532947
66Abnormality of the pons (HP:0007361)2.68209590
67Urinary glycosaminoglycan excretion (HP:0003541)2.66991751
68Mucopolysacchariduria (HP:0008155)2.66991751
69Dysostosis multiplex (HP:0000943)2.64753720
70Large for gestational age (HP:0001520)2.64633700
71Microretrognathia (HP:0000308)2.63981008
72Type I transferrin isoform profile (HP:0003642)2.62592549
73Increased intramyocellular lipid droplets (HP:0012240)2.61125539
74Broad alveolar ridges (HP:0000187)2.58387260
75Joint stiffness (HP:0001387)2.58040793
76Breast hypoplasia (HP:0003187)2.55043296
77Abnormality of the aortic arch (HP:0012303)2.54291188
78Hypotrichosis (HP:0001006)2.50735455
79Abnormality of the preputium (HP:0100587)2.50189921
80Premature skin wrinkling (HP:0100678)2.48920762
81Progressive macrocephaly (HP:0004481)2.48760604
82Increased muscle lipid content (HP:0009058)2.48151869
83Acute lymphatic leukemia (HP:0006721)2.47040500
84Meckel diverticulum (HP:0002245)2.46692481
85Aplasia/Hypoplasia of the uvula (HP:0010293)2.45895516
86Abnormality of homocysteine metabolism (HP:0010919)2.45677305
87Homocystinuria (HP:0002156)2.45677305
88Growth hormone excess (HP:0000845)2.44672763
89Lactic acidosis (HP:0003128)2.43573827
90Renal Fanconi syndrome (HP:0001994)2.42893534
91IgA deficiency (HP:0002720)2.42384320
92Reduced antithrombin III activity (HP:0001976)2.41618112
93Hypotelorism (HP:0000601)2.41457143
94Short thumb (HP:0009778)2.38735020
95Pendular nystagmus (HP:0012043)2.38660489
96Abnormality of alanine metabolism (HP:0010916)2.38130513
97Hyperalaninemia (HP:0003348)2.38130513
98Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.38130513
99Hypoplasia of the radius (HP:0002984)2.36176160
100Abnormality of the labia minora (HP:0012880)2.35764026
101Abnormality of polysaccharide metabolism (HP:0011012)2.34622514
102Abnormality of glycosaminoglycan metabolism (HP:0004371)2.34622514
103Abnormality of mucopolysaccharide metabolism (HP:0011020)2.34622514
104Diaphragmatic weakness (HP:0009113)2.31013287
105Coronal craniosynostosis (HP:0004440)2.30621683
106Amelogenesis imperfecta (HP:0000705)2.27246476
107Cheilitis (HP:0100825)2.24906392
108Hypokinesia (HP:0002375)2.24730832
109Redundant skin (HP:0001582)2.20931956
110Cerebral hypomyelination (HP:0006808)2.19604398
111Birth length less than 3rd percentile (HP:0003561)2.17235423
112Bifid uvula (HP:0000193)2.16585571
113Hypochromic anemia (HP:0001931)2.16299373
114Macrocytic anemia (HP:0001972)2.15762942
115Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.13683059
116Bowed forearm bones (HP:0003956)2.13646108
117Bowing of the arm (HP:0006488)2.13646108
118Progressive microcephaly (HP:0000253)2.13439428
119Abnormality of the carotid arteries (HP:0005344)2.11769408
120Methylmalonic acidemia (HP:0002912)2.11041386
121Cerebral edema (HP:0002181)2.10876341
122Exertional dyspnea (HP:0002875)2.09843185
123IgG deficiency (HP:0004315)2.09680503
124Abnormal protein N-linked glycosylation (HP:0012347)2.09455833
125Abnormal protein glycosylation (HP:0012346)2.09455833
126Abnormal glycosylation (HP:0012345)2.09455833
127Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.09455833
128Volvulus (HP:0002580)2.08422888
129Alacrima (HP:0000522)2.07336309
130Choanal stenosis (HP:0000452)2.06522603
131Pancreatic islet-cell hyperplasia (HP:0004510)2.05305480
132Abnormality of chromosome stability (HP:0003220)2.05031035
133Hyperglycinuria (HP:0003108)2.04256307
134Exercise intolerance (HP:0003546)2.03481029
135Clubbing of toes (HP:0100760)2.03477210
1363-Methylglutaconic aciduria (HP:0003535)2.03073877
137Methylmalonic aciduria (HP:0012120)2.02580351
138Bulbar palsy (HP:0001283)2.00949944
139Median cleft lip (HP:0000161)2.00833609
140Astrocytoma (HP:0009592)2.00805806
141Abnormality of the astrocytes (HP:0100707)2.00805806
142Ragged-red muscle fibers (HP:0003200)1.99834161
143Paralysis (HP:0003470)1.95294570
144Spinal muscular atrophy (HP:0007269)1.95240930
145Hyperthyroidism (HP:0000836)1.93756549
146Clumsiness (HP:0002312)1.93590707
147Abnormal number of erythroid precursors (HP:0012131)1.92041441
148Abnormality of the ileum (HP:0001549)1.91562497
149Reticulocytopenia (HP:0001896)1.91444810
150Abnormality of cells of the erythroid lineage (HP:0012130)1.91343164
151Rectal prolapse (HP:0002035)1.91329421
152Premature ovarian failure (HP:0008209)1.90564164
153Pancytopenia (HP:0001876)1.90349930
154Abnormality of the lower motor neuron (HP:0002366)1.88021795
155Ectopic kidney (HP:0000086)1.87580911
156Pallor (HP:0000980)1.87290397
157Aplasia of the musculature (HP:0100854)1.86902909
158Abnormal respiratory motile cilium morphology (HP:0005938)1.86584188
159Abnormal respiratory epithelium morphology (HP:0012253)1.86584188
160Hamartoma (HP:0010566)1.86387454
161Gastrointestinal atresia (HP:0002589)1.85837863
162Abnormality of T cell physiology (HP:0011840)1.84044732
163Ketosis (HP:0001946)1.83730052
164Respiratory failure (HP:0002878)1.82713906
165Cleft eyelid (HP:0000625)1.80596977
166Hypoalbuminemia (HP:0003073)1.79853330
167Abnormal albumin level (HP:0012116)1.79853330
168Lethargy (HP:0001254)1.79113250
169Aplasia/Hypoplasia of the sacrum (HP:0008517)1.78920588
170Leukodystrophy (HP:0002415)1.78710367
171Increased neuronal autofluorescent lipopigment (HP:0002074)1.77711991
172Lip pit (HP:0100267)1.76508000
173Congenital stationary night blindness (HP:0007642)1.72021272
174Megaloblastic anemia (HP:0001889)1.70998743
175Oral leukoplakia (HP:0002745)1.69909878
176Abnormality of serum amino acid levels (HP:0003112)1.67586520
177Horseshoe kidney (HP:0000085)1.67137757
178Aplasia/Hypoplasia involving the musculature (HP:0001460)1.64888004
179Seborrheic dermatitis (HP:0001051)1.63916299
180Duplicated collecting system (HP:0000081)1.63807592
181Ketoacidosis (HP:0001993)1.62393467
182Opisthotonus (HP:0002179)1.62169799

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK5.40305937
2TLK14.93343517
3MAPK154.74831380
4VRK24.55159176
5MAP3K64.54845987
6TRIB34.22626152
7DDR24.20476515
8MAP3K113.52410472
9PINK13.29973928
10SMG13.23835844
11MATK2.93576314
12DAPK12.88171574
13TYRO32.65135759
14PIM22.61660088
15FGR2.57824252
16ZAK2.26553880
17SIK12.25892731
18NME12.19769031
19TAF12.17823252
20AKT32.17288140
21PRKD21.98887855
22CDK71.93660200
23UHMK11.92481224
24DYRK1B1.89165748
25CSK1.87960150
26BUB11.87037975
27WEE11.83344552
28YES11.83001171
29MUSK1.76153612
30BMX1.71052325
31SRPK11.70678038
32PIM11.63346241
33INSRR1.59576613
34VRK11.57076404
35DYRK31.50627464
36PDGFRA1.41794767
37NEK21.30305812
38CDK61.23352375
39PLK11.21412361
40BCKDK1.21203570
41MAP2K21.20533407
42RPS6KL11.20262683
43RPS6KC11.20262683
44CHEK21.17665831
45EEF2K1.17015925
46NUAK11.14422179
47MAPK111.12718761
48BMPR1B1.10914561
49CSNK1G31.06565284
50LATS21.05612599
51EIF2AK11.05040326
52RPS6KA61.04893641
53NME20.97004555
54ILK0.93246072
55RAF10.90572970
56BRSK20.88894949
57MAP3K100.87213352
58PLK40.86853899
59IRAK30.86769413
60TRPM70.84995903
61RPS6KA50.83501044
62CHUK0.79956151
63MAP4K20.78518972
64TAOK20.78265440
65RPS6KB20.78188193
66NEK10.74970689
67GSK3A0.74728004
68PKN20.72109556
69CSNK1A1L0.71626275
70CDC42BPA0.71584223
71PHKG20.71437224
72PHKG10.71437224
73MAP4K10.70955430
74ATR0.70241446
75PIK3CA0.70074854
76EPHA20.69696150
77NEK60.69263547
78PRPF4B0.66791890
79IKBKB0.65394719
80MAP3K90.64137370
81MAPKAPK50.63421431
82FLT30.63186484
83PRKD30.61320472
84PRKAA10.61015108
85CSNK1G20.60984943
86MAPKAPK30.59641172
87EIF2AK20.59505859
88RPS6KA10.58039084
89ACVR1B0.57534978
90AURKA0.56501560
91TESK20.56339932
92TAOK10.55093975
93TESK10.54765979
94CDK20.54135597
95GRK10.54063310
96BRSK10.53544879
97MTOR0.52849870
98HIPK20.51135614
99CSNK2A10.49659039
100RPS6KA20.47566346
101LYN0.46698128
102CSNK1D0.44610979
103CDK40.43965009
104PDPK10.43532292
105RPS6KB10.43366774
106DAPK30.42609417
107AURKB0.42412160
108DYRK20.41454398
109CSNK1G10.40250020
110ADRBK20.39906761
111CSNK2A20.39802862
112CSNK1A10.39129941
113SCYL20.37397393
114CAMK1D0.37054630
115CHEK10.36201435
116PDK20.35391649
117MAPK40.34617466
118RPS6KA40.34539463
119CAMKK10.34350338
120MAPK30.34111768
121AKT20.32881936
122MAPK120.32733191
123MAP2K10.32203110
124MAPK80.31645484
125ALK0.31154776
126ARAF0.31092125
127PRKCI0.30461004
128STK380.30096634
129GRK60.30012032
130CDC70.29009452
131MAPK10.28787383
132CDK190.27977406
133EGFR0.27622983
134TNK20.27521877
135PAK10.26971816
136TTK0.25023463
137ATM0.24326092
138CDK120.24035127
139CCNB10.22837327
140LCK0.22701801
141SIK20.22573240
142CAMK2G0.22086291
143CDK10.21997829
144MAPK100.20415146
145CAMK2B0.20380506
146PAK40.20137437
147MAPK140.19991540
148STK160.19912920
149ZAP700.18941682
150CDK80.18908926
151CDK11A0.17870276

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034305.08600563
2Base excision repair_Homo sapiens_hsa034104.82911045
3DNA replication_Homo sapiens_hsa030304.43802536
4Fatty acid biosynthesis_Homo sapiens_hsa000613.78085099
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.34890625
6Oxidative phosphorylation_Homo sapiens_hsa001903.02103134
7Nucleotide excision repair_Homo sapiens_hsa034202.78503618
8RNA transport_Homo sapiens_hsa030132.74297600
9Spliceosome_Homo sapiens_hsa030402.62654151
10Parkinsons disease_Homo sapiens_hsa050122.49864477
11Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.22774931
12Homologous recombination_Homo sapiens_hsa034402.16525828
13Ribosome_Homo sapiens_hsa030102.04770229
14Huntingtons disease_Homo sapiens_hsa050161.97559483
15mRNA surveillance pathway_Homo sapiens_hsa030151.96194381
16RNA polymerase_Homo sapiens_hsa030201.95635271
17Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.91192140
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.86241599
19Circadian rhythm_Homo sapiens_hsa047101.82947856
20Fanconi anemia pathway_Homo sapiens_hsa034601.82472818
21Cell cycle_Homo sapiens_hsa041101.78647241
22p53 signaling pathway_Homo sapiens_hsa041151.78248981
23mTOR signaling pathway_Homo sapiens_hsa041501.75213059
24Sulfur relay system_Homo sapiens_hsa041221.74570689
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.69646687
26Folate biosynthesis_Homo sapiens_hsa007901.62753093
27Alzheimers disease_Homo sapiens_hsa050101.61664057
28Proteasome_Homo sapiens_hsa030501.56778994
29Biosynthesis of amino acids_Homo sapiens_hsa012301.52889147
30Primary immunodeficiency_Homo sapiens_hsa053401.48524908
31Vitamin B6 metabolism_Homo sapiens_hsa007501.44531007
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.42981300
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.36889059
34Notch signaling pathway_Homo sapiens_hsa043301.34874314
35Selenocompound metabolism_Homo sapiens_hsa004501.30916816
36Arginine and proline metabolism_Homo sapiens_hsa003301.28780974
37Pyrimidine metabolism_Homo sapiens_hsa002401.27673425
38Oocyte meiosis_Homo sapiens_hsa041141.26441244
39Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.18895332
40Fructose and mannose metabolism_Homo sapiens_hsa000511.17671065
41Longevity regulating pathway - mammal_Homo sapiens_hsa042111.13730317
42Hippo signaling pathway_Homo sapiens_hsa043901.11114245
43Hedgehog signaling pathway_Homo sapiens_hsa043401.10748641
44Shigellosis_Homo sapiens_hsa051311.10702263
45Basal transcription factors_Homo sapiens_hsa030221.09960307
462-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.08987936
47Cardiac muscle contraction_Homo sapiens_hsa042601.08558604
48Lysine degradation_Homo sapiens_hsa003101.04678758
49Transcriptional misregulation in cancer_Homo sapiens_hsa052021.00717303
50Caffeine metabolism_Homo sapiens_hsa002321.00663193
51VEGF signaling pathway_Homo sapiens_hsa043700.96616047
52Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.95283270
53Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.94830038
54Pyruvate metabolism_Homo sapiens_hsa006200.92623962
55Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.91800757
56RNA degradation_Homo sapiens_hsa030180.84861379
57Bladder cancer_Homo sapiens_hsa052190.81080789
58Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80320766
59Systemic lupus erythematosus_Homo sapiens_hsa053220.78186040
60Metabolic pathways_Homo sapiens_hsa011000.77212458
61Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.76071967
62Cyanoamino acid metabolism_Homo sapiens_hsa004600.74889650
63Colorectal cancer_Homo sapiens_hsa052100.73106784
64Adherens junction_Homo sapiens_hsa045200.73102878
65Epstein-Barr virus infection_Homo sapiens_hsa051690.72170715
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71598316
67Vitamin digestion and absorption_Homo sapiens_hsa049770.71575167
68TGF-beta signaling pathway_Homo sapiens_hsa043500.71015011
69Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.70030977
70Collecting duct acid secretion_Homo sapiens_hsa049660.69628855
71Acute myeloid leukemia_Homo sapiens_hsa052210.68746432
72Alcoholism_Homo sapiens_hsa050340.68075039
73Wnt signaling pathway_Homo sapiens_hsa043100.67167522
74Protein export_Homo sapiens_hsa030600.62737051
75Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.58244299
76Thyroid cancer_Homo sapiens_hsa052160.57325642
77Herpes simplex infection_Homo sapiens_hsa051680.56020493
78Legionellosis_Homo sapiens_hsa051340.54579685
79Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53793937
80Galactose metabolism_Homo sapiens_hsa000520.53459976
81One carbon pool by folate_Homo sapiens_hsa006700.53078422
82Purine metabolism_Homo sapiens_hsa002300.52809734
83Viral carcinogenesis_Homo sapiens_hsa052030.51741034
84Tryptophan metabolism_Homo sapiens_hsa003800.50108965
85Carbon metabolism_Homo sapiens_hsa012000.49495553
86Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.46678414
87Sulfur metabolism_Homo sapiens_hsa009200.46572475
88Non-homologous end-joining_Homo sapiens_hsa034500.44503988
89Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.44188757
90Glycosaminoglycan degradation_Homo sapiens_hsa005310.44054046
91Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43038870
92Choline metabolism in cancer_Homo sapiens_hsa052310.43025377
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.42891960
94Butanoate metabolism_Homo sapiens_hsa006500.41908289
95Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.41504467
96Pentose phosphate pathway_Homo sapiens_hsa000300.39912711
97Maturity onset diabetes of the young_Homo sapiens_hsa049500.39904026
98B cell receptor signaling pathway_Homo sapiens_hsa046620.39643342
99Chemical carcinogenesis_Homo sapiens_hsa052040.38905574
100Fatty acid metabolism_Homo sapiens_hsa012120.38297944
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.38153524
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37948209
103Insulin signaling pathway_Homo sapiens_hsa049100.37666999
104Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.37390322
105beta-Alanine metabolism_Homo sapiens_hsa004100.35705971
106Cysteine and methionine metabolism_Homo sapiens_hsa002700.35047431
107HTLV-I infection_Homo sapiens_hsa051660.34440155
108Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34038765
109Basal cell carcinoma_Homo sapiens_hsa052170.33927471
110Glutathione metabolism_Homo sapiens_hsa004800.33588100
111Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.31494640
112Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.31302609
113Hepatitis B_Homo sapiens_hsa051610.31084976
114Regulation of actin cytoskeleton_Homo sapiens_hsa048100.31028428
115AMPK signaling pathway_Homo sapiens_hsa041520.30171698
116Regulation of autophagy_Homo sapiens_hsa041400.29951835
117ErbB signaling pathway_Homo sapiens_hsa040120.29808083
118Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.29100532
119Peroxisome_Homo sapiens_hsa041460.29062223
120MicroRNAs in cancer_Homo sapiens_hsa052060.28742693
121Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.28584236
122Small cell lung cancer_Homo sapiens_hsa052220.28388190
123Steroid biosynthesis_Homo sapiens_hsa001000.28313039
124Chronic myeloid leukemia_Homo sapiens_hsa052200.26783017
125N-Glycan biosynthesis_Homo sapiens_hsa005100.25826570
126Glycerophospholipid metabolism_Homo sapiens_hsa005640.24729442
127Gap junction_Homo sapiens_hsa045400.24574707
128Viral myocarditis_Homo sapiens_hsa054160.23728554
129HIF-1 signaling pathway_Homo sapiens_hsa040660.23580160
130Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.21345166
131Melanoma_Homo sapiens_hsa052180.20632148
132Fatty acid elongation_Homo sapiens_hsa000620.20087808
133Pentose and glucuronate interconversions_Homo sapiens_hsa000400.19202688
134Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.19117826
135Tyrosine metabolism_Homo sapiens_hsa003500.18830423
136Steroid hormone biosynthesis_Homo sapiens_hsa001400.17385094
137Nicotine addiction_Homo sapiens_hsa050330.17267768
138Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.17178945
139Drug metabolism - other enzymes_Homo sapiens_hsa009830.16676514
140Measles_Homo sapiens_hsa051620.15890948
141Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.15646076
142Tight junction_Homo sapiens_hsa045300.14140978
143Taste transduction_Homo sapiens_hsa047420.13225691
144Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.12249065
145Propanoate metabolism_Homo sapiens_hsa006400.11730389
146Phenylalanine metabolism_Homo sapiens_hsa003600.10172386

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