Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of memory T cell differentiation (GO:0043380) | 5.67660690 |
2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.32228597 |
3 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.15334847 |
4 | negative regulation of cell killing (GO:0031342) | 5.15334847 |
5 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.42889333 |
6 | regulation of MHC class I biosynthetic process (GO:0045343) | 4.37289169 |
7 | negative regulation of type 2 immune response (GO:0002829) | 4.29465233 |
8 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.07245152 |
9 | positive regulation of interleukin-1 secretion (GO:0050716) | 4.05954029 |
10 | positive regulation by symbiont of host defense response (GO:0052509) | 3.98427647 |
11 | modulation by symbiont of host defense response (GO:0052031) | 3.98427647 |
12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 3.98427647 |
13 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 3.98427647 |
14 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 3.98427647 |
15 | modulation by symbiont of host immune response (GO:0052553) | 3.98427647 |
16 | cellular extravasation (GO:0045123) | 3.92895922 |
17 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.91888801 |
18 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.88915796 |
19 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.76784656 |
20 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.71310482 |
21 | response to interleukin-15 (GO:0070672) | 3.62940925 |
22 | maintenance of gastrointestinal epithelium (GO:0030277) | 3.58269970 |
23 | cellular response to interleukin-15 (GO:0071350) | 3.58246668 |
24 | negative regulation of interleukin-12 production (GO:0032695) | 3.57055305 |
25 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.56554111 |
26 | hepatocyte apoptotic process (GO:0097284) | 3.51770786 |
27 | germinal center formation (GO:0002467) | 3.50354208 |
28 | negative regulation of T cell mediated immunity (GO:0002710) | 3.50213325 |
29 | definitive hemopoiesis (GO:0060216) | 3.48044803 |
30 | doxorubicin metabolic process (GO:0044598) | 3.46710623 |
31 | daunorubicin metabolic process (GO:0044597) | 3.46710623 |
32 | polyketide metabolic process (GO:0030638) | 3.46710623 |
33 | lymphocyte chemotaxis (GO:0048247) | 3.46415176 |
34 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.46382075 |
35 | defense response to protozoan (GO:0042832) | 3.40778667 |
36 | regulation of establishment of cell polarity (GO:2000114) | 3.40717664 |
37 | regulation of interleukin-1 secretion (GO:0050704) | 3.40354990 |
38 | macrophage activation involved in immune response (GO:0002281) | 3.35874543 |
39 | neural tube formation (GO:0001841) | 3.35818374 |
40 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.33755806 |
41 | response to muramyl dipeptide (GO:0032495) | 3.33530465 |
42 | neutrophil activation involved in immune response (GO:0002283) | 3.32419353 |
43 | B cell receptor signaling pathway (GO:0050853) | 3.20067066 |
44 | neutrophil activation (GO:0042119) | 3.19746278 |
45 | * response to type I interferon (GO:0034340) | 3.19022770 |
46 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.18899404 |
47 | respiratory burst (GO:0045730) | 3.18668299 |
48 | response to peptidoglycan (GO:0032494) | 3.18085780 |
49 | response to protozoan (GO:0001562) | 3.17253383 |
50 | regulation of T cell tolerance induction (GO:0002664) | 3.15158236 |
51 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.14748309 |
52 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.14748309 |
53 | negative thymic T cell selection (GO:0045060) | 3.12995980 |
54 | negative T cell selection (GO:0043383) | 3.10452917 |
55 | detection of molecule of bacterial origin (GO:0032490) | 3.10069521 |
56 | * cellular response to type I interferon (GO:0071357) | 3.09757144 |
57 | * type I interferon signaling pathway (GO:0060337) | 3.09757144 |
58 | B cell homeostasis (GO:0001782) | 3.08705820 |
59 | macrophage activation (GO:0042116) | 3.08659625 |
60 | T cell migration (GO:0072678) | 3.07669838 |
61 | negative regulation of granulocyte differentiation (GO:0030853) | 3.07486334 |
62 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 3.07058820 |
63 | cellular response to ethanol (GO:0071361) | 3.06610847 |
64 | immunoglobulin mediated immune response (GO:0016064) | 3.05577112 |
65 | leukocyte aggregation (GO:0070486) | 3.05479377 |
66 | detection of bacterium (GO:0016045) | 3.04684741 |
67 | neutrophil mediated immunity (GO:0002446) | 3.04509853 |
68 | interferon-gamma production (GO:0032609) | 3.03976545 |
69 | positive regulation of interleukin-1 production (GO:0032732) | 3.03882674 |
70 | dendritic cell chemotaxis (GO:0002407) | 3.03087764 |
71 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.02093222 |
72 | megakaryocyte development (GO:0035855) | 3.01716829 |
73 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.01108848 |
74 | positive regulation of interferon-alpha production (GO:0032727) | 3.00783483 |
75 | mast cell activation (GO:0045576) | 3.00711628 |
76 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.99837605 |
77 | negative regulation of leukocyte mediated immunity (GO:0002704) | 2.99405223 |
78 | myeloid leukocyte mediated immunity (GO:0002444) | 2.98083580 |
79 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.97296525 |
80 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.96970986 |
81 | response to host immune response (GO:0052572) | 2.96970986 |
82 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.95372134 |
83 | dendritic cell migration (GO:0036336) | 2.93170807 |
84 | myeloid cell activation involved in immune response (GO:0002275) | 2.91999996 |
85 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.89400551 |
86 | positive regulation of B cell differentiation (GO:0045579) | 2.89256455 |
87 | positive regulation of mast cell activation (GO:0033005) | 2.89007556 |
88 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.88998178 |
89 | granulocyte activation (GO:0036230) | 2.88806374 |
90 | negative regulation of adaptive immune response (GO:0002820) | 2.87959855 |
91 | myeloid dendritic cell activation (GO:0001773) | 2.85189347 |
92 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.84945839 |
93 | regulation of interferon-alpha production (GO:0032647) | 2.84825038 |
94 | detection of other organism (GO:0098543) | 2.84415007 |
95 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.84201747 |
96 | amyloid precursor protein catabolic process (GO:0042987) | 2.83178580 |
97 | establishment of protein localization to Golgi (GO:0072600) | 2.83001388 |
98 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 2.82316210 |
99 | regulation of establishment or maintenance of cell polarity (GO:0032878) | 2.80770305 |
100 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.80392570 |
101 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 2.80165029 |
102 | regulation of B cell differentiation (GO:0045577) | 2.80041607 |
103 | regulation of mast cell degranulation (GO:0043304) | 2.79854900 |
104 | detection of biotic stimulus (GO:0009595) | 2.79731799 |
105 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.78687504 |
106 | lymphocyte homeostasis (GO:0002260) | 2.78663700 |
107 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.77712100 |
108 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.76727910 |
109 | negative regulation of phagocytosis (GO:0050765) | 2.75516919 |
110 | positive regulation of granulocyte differentiation (GO:0030854) | 2.74671108 |
111 | regulation of regulatory T cell differentiation (GO:0045589) | 2.74650553 |
112 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.73686863 |
113 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.73686863 |
114 | histamine secretion (GO:0001821) | 2.69967195 |
115 | regulation of gamma-delta T cell activation (GO:0046643) | 2.69675494 |
116 | erythrocyte maturation (GO:0043249) | 2.69616404 |
117 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 2.69157031 |
118 | negative regulation of B cell mediated immunity (GO:0002713) | 2.69157031 |
119 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.69080315 |
120 | detection of external biotic stimulus (GO:0098581) | 2.69067310 |
121 | T cell homeostasis (GO:0043029) | 2.67069297 |
122 | negative regulation of protein tyrosine kinase activity (GO:0061099) | 2.66907740 |
123 | pinocytosis (GO:0006907) | 2.66544369 |
124 | leukotriene metabolic process (GO:0006691) | 2.65735345 |
125 | response to pheromone (GO:0019236) | 2.65009170 |
126 | activated T cell proliferation (GO:0050798) | 2.64387952 |
127 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 2.64198984 |
128 | response to host (GO:0075136) | 2.64198984 |
129 | response to host defenses (GO:0052200) | 2.64198984 |
130 | positive regulation of macrophage differentiation (GO:0045651) | 2.64076505 |
131 | microglial cell activation (GO:0001774) | 2.64018015 |
132 | leukocyte cell-cell adhesion (GO:0007159) | 2.64013216 |
133 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.62827976 |
134 | mature B cell differentiation (GO:0002335) | 2.61395531 |
135 | leukocyte migration involved in inflammatory response (GO:0002523) | 2.61390846 |
136 | regulation of type 2 immune response (GO:0002828) | 2.60570102 |
137 | regulation of RIG-I signaling pathway (GO:0039535) | 2.59755499 |
138 | mature B cell differentiation involved in immune response (GO:0002313) | 2.59743623 |
139 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.58906291 |
140 | regulation of mast cell activation (GO:0033003) | 2.58805774 |
141 | epithelial structure maintenance (GO:0010669) | 2.58001054 |
142 | positive T cell selection (GO:0043368) | 2.57598742 |
143 | positive thymic T cell selection (GO:0045059) | 2.55745026 |
144 | regulation of antigen processing and presentation (GO:0002577) | 2.54837639 |
145 | protein targeting to Golgi (GO:0000042) | 2.54304917 |
146 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.53331651 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.53407043 |
2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.91303320 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.31945362 |
4 | GATA1_22025678_ChIP-Seq_K562_Human | 4.15429050 |
5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.13090283 |
6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.07716746 |
7 | SCL_19346495_ChIP-Seq_HPC-7_Human | 4.07233183 |
8 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.89584985 |
9 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.69974282 |
10 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.49014526 |
11 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.43208565 |
12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.10089841 |
13 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.06682995 |
14 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.95883386 |
15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.91380682 |
16 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.61097188 |
17 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.55141001 |
18 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.44597198 |
19 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.41210741 |
20 | * FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.31754270 |
21 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.28961761 |
22 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.25448043 |
23 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.17197901 |
24 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.14507910 |
25 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.13303856 |
26 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.12623832 |
27 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.10160051 |
28 | SPI1_23127762_ChIP-Seq_K562_Human | 2.00535490 |
29 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.98534594 |
30 | * MYB_26560356_Chip-Seq_TH2_Human | 1.98042110 |
31 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.94556180 |
32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.82219348 |
33 | VDR_22108803_ChIP-Seq_LS180_Human | 1.75278253 |
34 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.73336144 |
35 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.72754398 |
36 | MAF_26560356_Chip-Seq_TH1_Human | 1.69048914 |
37 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.68634401 |
38 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.67590470 |
39 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.66487491 |
40 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.66331393 |
41 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.66096625 |
42 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65966872 |
43 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.65274903 |
44 | * MYB_26560356_Chip-Seq_TH1_Human | 1.63545852 |
45 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.63473337 |
46 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.62143086 |
47 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.60716799 |
48 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.56842564 |
49 | GATA2_19941826_ChIP-Seq_K562_Human | 1.56477581 |
50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.56163972 |
51 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53848437 |
52 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.52625169 |
53 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.49939337 |
54 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.49596749 |
55 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.49409537 |
56 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.47501026 |
57 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.47419226 |
58 | UTX_26944678_Chip-Seq_JUKART_Human | 1.46103495 |
59 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45862481 |
60 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.44310069 |
61 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.43928862 |
62 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.42309154 |
63 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.41579157 |
64 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.40224558 |
65 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.39596096 |
66 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.38735963 |
67 | GATA1_19941826_ChIP-Seq_K562_Human | 1.37538299 |
68 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.36034319 |
69 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.34283808 |
70 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.31892761 |
71 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.31167037 |
72 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.28129733 |
73 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.27870977 |
74 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.26887340 |
75 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.26379996 |
76 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.24696206 |
77 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.23014086 |
78 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.22854574 |
79 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.22436140 |
80 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.21344679 |
81 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.17477093 |
82 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.17125826 |
83 | * CDX2_22108803_ChIP-Seq_LS180_Human | 1.15946283 |
84 | STAT3_23295773_ChIP-Seq_U87_Human | 1.15853714 |
85 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.15744481 |
86 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15731901 |
87 | * KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 1.15654693 |
88 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15493882 |
89 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.14995771 |
90 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.14844386 |
91 | * SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.12465324 |
92 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.11676566 |
93 | * EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.11650037 |
94 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.08885072 |
95 | TCF4_23295773_ChIP-Seq_U87_Human | 1.08735892 |
96 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.08236709 |
97 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.08202710 |
98 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06780635 |
99 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.06592586 |
100 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.06245102 |
101 | * NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.04277893 |
102 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.04264623 |
103 | * SOX2_20726797_ChIP-Seq_SW620_Human | 1.04142258 |
104 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03513675 |
105 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.03501366 |
106 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.02182267 |
107 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01911266 |
108 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01381011 |
109 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00908301 |
110 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.00584791 |
111 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.00574159 |
112 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.00411877 |
113 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00155953 |
114 | P300_19829295_ChIP-Seq_ESCs_Human | 0.99900426 |
115 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.99643025 |
116 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.99561847 |
117 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.99368105 |
118 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.98755968 |
119 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.98641738 |
120 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.97585578 |
121 | MYC_22102868_ChIP-Seq_BL_Human | 0.97377899 |
122 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.96730511 |
123 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.95664324 |
124 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.95410550 |
125 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.95410550 |
126 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.94144354 |
127 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.93747018 |
128 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.93066199 |
129 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.92951092 |
130 | AR_25329375_ChIP-Seq_VCAP_Human | 0.92188638 |
131 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.90408110 |
132 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.88657224 |
133 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.87958082 |
134 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.87531626 |
135 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81842181 |
136 | GATA3_26560356_Chip-Seq_TH2_Human | 0.79947746 |
137 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.78857913 |
138 | * GATA4_25053715_ChIP-Seq_YYC3_Human | 0.77612887 |
139 | * MAF_26560356_Chip-Seq_TH2_Human | 0.76926650 |
140 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.74669379 |
141 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.72834639 |
142 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.72761627 |
143 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.72407029 |
144 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.72045386 |
145 | * FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.71774783 |
146 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.71227852 |
147 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.70848522 |
148 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.69578285 |
149 | * CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.69490104 |
150 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.69440379 |
151 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.68984630 |
152 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.66256264 |
153 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.64717347 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 3.59038909 |
2 | MP0005671_abnormal_response_to | 3.10497894 |
3 | MP0009785_altered_susceptibility_to | 2.92983093 |
4 | MP0001873_stomach_inflammation | 2.92440849 |
5 | MP0002396_abnormal_hematopoietic_system | 2.82786310 |
6 | MP0005257_abnormal_intraocular_pressure | 2.82171322 |
7 | MP0003436_decreased_susceptibility_to | 2.68555692 |
8 | MP0002148_abnormal_hypersensitivity_rea | 2.56750092 |
9 | * MP0005025_abnormal_response_to | 2.48350479 |
10 | MP0003724_increased_susceptibility_to | 2.45541340 |
11 | MP0002419_abnormal_innate_immunity | 2.43897342 |
12 | MP0000685_abnormal_immune_system | 2.42183098 |
13 | MP0005000_abnormal_immune_tolerance | 2.42055563 |
14 | MP0010155_abnormal_intestine_physiology | 2.41685398 |
15 | MP0001800_abnormal_humoral_immune | 2.39046973 |
16 | MP0002452_abnormal_antigen_presenting | 2.38779980 |
17 | MP0006054_spinal_hemorrhage | 2.37418120 |
18 | MP0005464_abnormal_platelet_physiology | 2.37259897 |
19 | MP0003866_abnormal_defecation | 2.30488376 |
20 | MP0000569_abnormal_digit_pigmentation | 2.30133998 |
21 | MP0000490_abnormal_crypts_of | 2.28136579 |
22 | MP0005174_abnormal_tail_pigmentation | 2.26266017 |
23 | MP0005058_abnormal_lysosome_morphology | 2.24452599 |
24 | MP0002723_abnormal_immune_serum | 2.24034265 |
25 | * MP0001819_abnormal_immune_cell | 2.23634544 |
26 | MP0003252_abnormal_bile_duct | 2.23500286 |
27 | * MP0002420_abnormal_adaptive_immunity | 2.20497673 |
28 | MP0005387_immune_system_phenotype | 2.08638311 |
29 | MP0001790_abnormal_immune_system | 2.08638311 |
30 | MP0000465_gastrointestinal_hemorrhage | 2.05951271 |
31 | MP0004381_abnormal_hair_follicle | 2.00310132 |
32 | MP0003300_gastrointestinal_ulcer | 1.95146180 |
33 | MP0002398_abnormal_bone_marrow | 1.92378616 |
34 | MP0005377_hearing/vestibular/ear_phenot | 1.85826572 |
35 | MP0003878_abnormal_ear_physiology | 1.85826572 |
36 | MP0003195_calcinosis | 1.82234903 |
37 | MP0003011_delayed_dark_adaptation | 1.82010205 |
38 | MP0004947_skin_inflammation | 1.79946032 |
39 | MP0001663_abnormal_digestive_system | 1.76392933 |
40 | MP0003303_peritoneal_inflammation | 1.74926528 |
41 | MP0000716_abnormal_immune_system | 1.73454959 |
42 | MP0006082_CNS_inflammation | 1.70918808 |
43 | MP0002166_altered_tumor_susceptibility | 1.70147515 |
44 | MP0001986_abnormal_taste_sensitivity | 1.70013918 |
45 | MP0003763_abnormal_thymus_physiology | 1.69262807 |
46 | MP0005310_abnormal_salivary_gland | 1.67034537 |
47 | MP0001845_abnormal_inflammatory_respons | 1.65777152 |
48 | MP0004147_increased_porphyrin_level | 1.63034008 |
49 | MP0005075_abnormal_melanosome_morpholog | 1.61784990 |
50 | MP0002405_respiratory_system_inflammati | 1.57560348 |
51 | MP0003191_abnormal_cellular_cholesterol | 1.56238362 |
52 | MP0003656_abnormal_erythrocyte_physiolo | 1.55929415 |
53 | MP0002277_abnormal_respiratory_mucosa | 1.53626725 |
54 | MP0002006_tumorigenesis | 1.52946483 |
55 | MP0009333_abnormal_splenocyte_physiolog | 1.51101369 |
56 | MP0002429_abnormal_blood_cell | 1.47823919 |
57 | * MP0002722_abnormal_immune_system | 1.46857113 |
58 | MP0000689_abnormal_spleen_morphology | 1.46033110 |
59 | MP0000015_abnormal_ear_pigmentation | 1.44104416 |
60 | MP0000371_diluted_coat_color | 1.44047666 |
61 | MP0001533_abnormal_skeleton_physiology | 1.34386497 |
62 | MP0005167_abnormal_blood-brain_barrier | 1.30634215 |
63 | MP0002132_abnormal_respiratory_system | 1.28565077 |
64 | MP0005397_hematopoietic_system_phenotyp | 1.28253693 |
65 | MP0001545_abnormal_hematopoietic_system | 1.28253693 |
66 | MP0002138_abnormal_hepatobiliary_system | 1.28179694 |
67 | MP0003183_abnormal_peptide_metabolism | 1.27761140 |
68 | MP0008057_abnormal_DNA_replication | 1.27698881 |
69 | MP0004808_abnormal_hematopoietic_stem | 1.25914321 |
70 | MP0004883_abnormal_blood_vessel | 1.24826623 |
71 | MP0005381_digestive/alimentary_phenotyp | 1.23956551 |
72 | MP0002095_abnormal_skin_pigmentation | 1.18576657 |
73 | MP0009278_abnormal_bone_marrow | 1.15746594 |
74 | MP0002876_abnormal_thyroid_physiology | 1.14528371 |
75 | MP0001851_eye_inflammation | 1.14147736 |
76 | MP0008260_abnormal_autophagy | 1.13493969 |
77 | MP0000343_altered_response_to | 1.12936143 |
78 | MP0000477_abnormal_intestine_morphology | 1.12898474 |
79 | MP0002998_abnormal_bone_remodeling | 1.11910679 |
80 | MP0003045_fibrosis | 1.10720646 |
81 | MP0008469_abnormal_protein_level | 1.09112899 |
82 | MP0009764_decreased_sensitivity_to | 1.08002404 |
83 | MP0004130_abnormal_muscle_cell | 1.07267900 |
84 | MP0002822_catalepsy | 1.07250163 |
85 | MP0001853_heart_inflammation | 1.07019872 |
86 | MP0001501_abnormal_sleep_pattern | 1.06668437 |
87 | MP0005166_decreased_susceptibility_to | 1.06625271 |
88 | MP0004264_abnormal_extraembryonic_tissu | 1.05368490 |
89 | MP0008877_abnormal_DNA_methylation | 1.01103865 |
90 | * MP0000703_abnormal_thymus_morphology | 0.98857867 |
91 | MP0005164_abnormal_response_to | 0.97507728 |
92 | MP0000427_abnormal_hair_cycle | 0.94030965 |
93 | MP0002928_abnormal_bile_duct | 0.94029258 |
94 | MP0010386_abnormal_urinary_bladder | 0.90684259 |
95 | MP0002693_abnormal_pancreas_physiology | 0.90429820 |
96 | MP0005409_darkened_coat_color | 0.89465721 |
97 | MP0003868_abnormal_feces_composition | 0.88573714 |
98 | MP0001664_abnormal_digestion | 0.87276915 |
99 | MP0003690_abnormal_glial_cell | 0.86000358 |
100 | MP0003448_altered_tumor_morphology | 0.84560462 |
101 | MP0004510_myositis | 0.83550744 |
102 | MP0000858_altered_metastatic_potential | 0.83454114 |
103 | MP0003787_abnormal_imprinting | 0.80831869 |
104 | MP0008873_increased_physiological_sensi | 0.80217422 |
105 | MP0005253_abnormal_eye_physiology | 0.77925812 |
106 | MP0000681_abnormal_thyroid_gland | 0.77416989 |
107 | MP0003795_abnormal_bone_structure | 0.77292376 |
108 | MP0005085_abnormal_gallbladder_physiolo | 0.76897585 |
109 | MP0003828_pulmonary_edema | 0.75568467 |
110 | MP0004484_altered_response_of | 0.75529607 |
111 | MP0005083_abnormal_biliary_tract | 0.74515038 |
112 | MP0009763_increased_sensitivity_to | 0.74333562 |
113 | MP0008004_abnormal_stomach_pH | 0.72514232 |
114 | MP0009115_abnormal_fat_cell | 0.72436054 |
115 | MP0001666_abnormal_nutrient_absorption | 0.71479474 |
116 | MP0002933_joint_inflammation | 0.70885958 |
117 | MP0003172_abnormal_lysosome_physiology | 0.69779814 |
118 | MP0001968_abnormal_touch/_nociception | 0.69334446 |
119 | MP0000372_irregular_coat_pigmentation | 0.67755509 |
120 | MP0002009_preneoplasia | 0.67668249 |
121 | MP0000470_abnormal_stomach_morphology | 0.66977895 |
122 | MP0002089_abnormal_postnatal_growth/wei | 0.66560678 |
123 | MP0005670_abnormal_white_adipose | 0.65101730 |
124 | MP0000249_abnormal_blood_vessel | 0.64829262 |
125 | MP0002736_abnormal_nociception_after | 0.64505362 |
126 | MP0003646_muscle_fatigue | 0.61552736 |
127 | MP0003075_altered_response_to | 0.61534427 |
128 | MP0000604_amyloidosis | 0.61152705 |
129 | MP0005376_homeostasis/metabolism_phenot | 0.60981177 |
130 | MP0010307_abnormal_tumor_latency | 0.60712470 |
131 | MP0004043_abnormal_pH_regulation | 0.60700443 |
132 | MP0005390_skeleton_phenotype | 0.60208270 |
133 | MP0010352_gastrointestinal_tract_polyps | 0.60093227 |
134 | MP0002168_other_aberrant_phenotype | 0.57584150 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 5.64182551 |
2 | Recurrent bacterial skin infections (HP:0005406) | 5.29827402 |
3 | Eczematoid dermatitis (HP:0000976) | 4.97642216 |
4 | Genetic anticipation (HP:0003743) | 4.47084821 |
5 | Spinal cord lesions (HP:0100561) | 4.30724404 |
6 | Syringomyelia (HP:0003396) | 4.30724404 |
7 | Stomatitis (HP:0010280) | 4.09879297 |
8 | Recurrent cutaneous fungal infections (HP:0011370) | 4.00988432 |
9 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.00988432 |
10 | Recurrent fungal infections (HP:0002841) | 3.94487120 |
11 | Metaphyseal dysplasia (HP:0100255) | 3.87333582 |
12 | Vacuolated lymphocytes (HP:0001922) | 3.85166434 |
13 | Pustule (HP:0200039) | 3.85067995 |
14 | Recurrent skin infections (HP:0001581) | 3.82990933 |
15 | Myositis (HP:0100614) | 3.79000532 |
16 | Hypochromic microcytic anemia (HP:0004840) | 3.69148569 |
17 | Petechiae (HP:0000967) | 3.58756804 |
18 | Abnormality of macrophages (HP:0004311) | 3.55249929 |
19 | Chronic diarrhea (HP:0002028) | 3.51092292 |
20 | Absent frontal sinuses (HP:0002688) | 3.49895617 |
21 | Dysmetric saccades (HP:0000641) | 3.40632080 |
22 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.30093173 |
23 | Agnosia (HP:0010524) | 3.29023806 |
24 | Cheilitis (HP:0100825) | 3.26264034 |
25 | Gastrointestinal infarctions (HP:0005244) | 3.24188225 |
26 | Prolonged bleeding time (HP:0003010) | 3.21062090 |
27 | Gaze-evoked nystagmus (HP:0000640) | 3.19652110 |
28 | Mediastinal lymphadenopathy (HP:0100721) | 3.17193755 |
29 | Slow saccadic eye movements (HP:0000514) | 3.16103975 |
30 | Orchitis (HP:0100796) | 3.14194361 |
31 | Recurrent viral infections (HP:0004429) | 3.08503492 |
32 | Retrobulbar optic neuritis (HP:0100654) | 3.07654838 |
33 | Optic neuritis (HP:0100653) | 3.07654838 |
34 | Disinhibition (HP:0000734) | 3.06988933 |
35 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.05868425 |
36 | Autoimmune thrombocytopenia (HP:0001973) | 3.01008693 |
37 | Progressive cerebellar ataxia (HP:0002073) | 2.99932647 |
38 | Chest pain (HP:0100749) | 2.93086729 |
39 | IgM deficiency (HP:0002850) | 2.91124742 |
40 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.83825071 |
41 | Periodontitis (HP:0000704) | 2.76992298 |
42 | Meningitis (HP:0001287) | 2.76063131 |
43 | Chronic obstructive pulmonary disease (HP:0006510) | 2.70089068 |
44 | Obstructive lung disease (HP:0006536) | 2.70089068 |
45 | Gingivitis (HP:0000230) | 2.70016285 |
46 | Short middle phalanx of the 5th finger (HP:0004220) | 2.69306061 |
47 | Hypochromic anemia (HP:0001931) | 2.67480572 |
48 | Spondylolisthesis (HP:0003302) | 2.62774530 |
49 | Vasculitis (HP:0002633) | 2.62276830 |
50 | Recurrent bronchitis (HP:0002837) | 2.60368087 |
51 | Action tremor (HP:0002345) | 2.56211722 |
52 | Patchy hypopigmentation of hair (HP:0011365) | 2.50594304 |
53 | Poikilocytosis (HP:0004447) | 2.48588903 |
54 | Facial diplegia (HP:0001349) | 2.46270390 |
55 | Anorexia (HP:0002039) | 2.44887487 |
56 | Postural instability (HP:0002172) | 2.44505496 |
57 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 2.41172804 |
58 | Stomach cancer (HP:0012126) | 2.40991837 |
59 | Cellulitis (HP:0100658) | 2.40508858 |
60 | Recurrent pneumonia (HP:0006532) | 2.39391063 |
61 | Impaired platelet aggregation (HP:0003540) | 2.31127349 |
62 | Abnormal platelet function (HP:0011869) | 2.31127349 |
63 | Thickened calvaria (HP:0002684) | 2.28824981 |
64 | Epistaxis (HP:0000421) | 2.28197886 |
65 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 2.27217278 |
66 | Eosinophilia (HP:0001880) | 2.26739778 |
67 | Abnormality of T cell physiology (HP:0011840) | 2.24800281 |
68 | Keratoconjunctivitis (HP:0001096) | 2.24408452 |
69 | * Prostate neoplasm (HP:0100787) | 2.21396894 |
70 | Hemoptysis (HP:0002105) | 2.20552041 |
71 | Chronic otitis media (HP:0000389) | 2.20154161 |
72 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.19713942 |
73 | Osteomyelitis (HP:0002754) | 2.17951641 |
74 | Keratoconjunctivitis sicca (HP:0001097) | 2.17917596 |
75 | Autoimmune hemolytic anemia (HP:0001890) | 2.16849573 |
76 | Pulmonary embolism (HP:0002204) | 2.15916274 |
77 | IgG deficiency (HP:0004315) | 2.14558196 |
78 | Abnormality of eosinophils (HP:0001879) | 2.14472577 |
79 | Leukocytosis (HP:0001974) | 2.14079939 |
80 | Microcytic anemia (HP:0001935) | 2.12641042 |
81 | Inflammation of the large intestine (HP:0002037) | 2.10987152 |
82 | Granulocytopenia (HP:0001913) | 2.10925024 |
83 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.08736214 |
84 | Abnormality of the frontal sinuses (HP:0002687) | 2.05814197 |
85 | Increased cerebral lipofuscin (HP:0011813) | 2.04727299 |
86 | Pulmonary infiltrates (HP:0002113) | 2.02957973 |
87 | White forelock (HP:0002211) | 2.02305959 |
88 | Congenital stationary night blindness (HP:0007642) | 2.02033409 |
89 | Abnormality of T cells (HP:0002843) | 2.01489855 |
90 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.01443117 |
91 | Recurrent lower respiratory tract infections (HP:0002783) | 2.01021604 |
92 | Abnormality of the hepatic vasculature (HP:0006707) | 1.99654213 |
93 | Progressive inability to walk (HP:0002505) | 1.99652788 |
94 | Lymphopenia (HP:0001888) | 1.99527835 |
95 | Loss of speech (HP:0002371) | 1.99285992 |
96 | Vertigo (HP:0002321) | 1.98576860 |
97 | Agammaglobulinemia (HP:0004432) | 1.97867150 |
98 | Oligomenorrhea (HP:0000876) | 1.97709415 |
99 | Abnormality of the pleura (HP:0002103) | 1.96556327 |
100 | Thrombocytosis (HP:0001894) | 1.96160416 |
101 | Gangrene (HP:0100758) | 1.95355458 |
102 | Spontaneous hematomas (HP:0007420) | 1.94954430 |
103 | Abnormality of the fingertips (HP:0001211) | 1.94656307 |
104 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 1.94214690 |
105 | * Abnormality of the prostate (HP:0008775) | 1.93948677 |
106 | Episodic fever (HP:0001954) | 1.92648921 |
107 | Keratitis (HP:0000491) | 1.90685656 |
108 | Thyroiditis (HP:0100646) | 1.90279435 |
109 | Gastrointestinal inflammation (HP:0004386) | 1.89541406 |
110 | Peritonitis (HP:0002586) | 1.88651664 |
111 | Gingival bleeding (HP:0000225) | 1.88646444 |
112 | Panhypogammaglobulinemia (HP:0003139) | 1.88600915 |
113 | T lymphocytopenia (HP:0005403) | 1.88465069 |
114 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.87387959 |
115 | Hypoproteinemia (HP:0003075) | 1.87090224 |
116 | Urticaria (HP:0001025) | 1.86890422 |
117 | Congenital sensorineural hearing impairment (HP:0008527) | 1.86857899 |
118 | Acne (HP:0001061) | 1.86598656 |
119 | Hyperventilation (HP:0002883) | 1.86353949 |
120 | Polyneuropathy (HP:0001271) | 1.84237187 |
121 | Villous atrophy (HP:0011473) | 1.83911224 |
122 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.83911224 |
123 | Pancreatic cysts (HP:0001737) | 1.83148860 |
124 | Macular degeneration (HP:0000608) | 1.82388487 |
125 | Arterial thrombosis (HP:0004420) | 1.81914590 |
126 | Absent/shortened dynein arms (HP:0200106) | 1.80875733 |
127 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.80875733 |
128 | Hemiplegia (HP:0002301) | 1.80252439 |
129 | Inappropriate behavior (HP:0000719) | 1.80203653 |
130 | Sepsis (HP:0100806) | 1.80072159 |
131 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.79634794 |
132 | Systemic lupus erythematosus (HP:0002725) | 1.79532093 |
133 | Abnormality of T cell number (HP:0011839) | 1.78680278 |
134 | Recurrent sinusitis (HP:0011108) | 1.78152962 |
135 | Abnormality of glycolipid metabolism (HP:0010969) | 1.78051608 |
136 | Abnormality of liposaccharide metabolism (HP:0010968) | 1.78051608 |
137 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 1.78051608 |
138 | Abnormality of the renal cortex (HP:0011035) | 1.77929701 |
139 | Bone pain (HP:0002653) | 1.77398170 |
140 | Abnormality of B cell number (HP:0010975) | 1.76485447 |
141 | B lymphocytopenia (HP:0010976) | 1.76485447 |
142 | Abnormality of the parietal bone (HP:0002696) | 1.75559571 |
143 | Gastrointestinal stroma tumor (HP:0100723) | 1.73008588 |
144 | Abnormal platelet volume (HP:0011876) | 1.72683903 |
145 | Ectropion (HP:0000656) | 1.72521198 |
146 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.72519308 |
147 | Encephalitis (HP:0002383) | 1.69482839 |
148 | Purpura (HP:0000979) | 1.69386915 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MST1R | 5.98119907 |
2 | PIK3CA | 4.32588690 |
3 | CDK19 | 2.76604065 |
4 | MAP4K1 | 2.54419101 |
5 | KIT | 2.53047648 |
6 | TXK | 2.52727910 |
7 | MAP3K14 | 2.34129231 |
8 | SIK3 | 2.29436741 |
9 | BLK | 2.27913922 |
10 | CLK1 | 2.23146791 |
11 | OXSR1 | 2.13560097 |
12 | TNK2 | 2.07008045 |
13 | IRAK4 | 2.06358251 |
14 | JAK3 | 2.03778300 |
15 | TAOK3 | 1.92707014 |
16 | TYK2 | 1.88531447 |
17 | MAP3K2 | 1.80229672 |
18 | RIPK4 | 1.78300754 |
19 | IKBKE | 1.74358702 |
20 | SIK2 | 1.72049522 |
21 | IRAK3 | 1.71502717 |
22 | TBK1 | 1.67430138 |
23 | EEF2K | 1.66783213 |
24 | TEC | 1.63801957 |
25 | MAP2K2 | 1.63404254 |
26 | MATK | 1.43200371 |
27 | GRK1 | 1.43097559 |
28 | TGFBR2 | 1.41533026 |
29 | MET | 1.37678751 |
30 | ZAP70 | 1.36773272 |
31 | PTK2B | 1.35101480 |
32 | MAP3K7 | 1.31476105 |
33 | BTK | 1.30763385 |
34 | CDK9 | 1.30724305 |
35 | SYK | 1.30603955 |
36 | BMPR1B | 1.28769331 |
37 | CSF1R | 1.24340033 |
38 | FGFR3 | 1.21360684 |
39 | PIK3CG | 1.16853193 |
40 | FGR | 1.14596313 |
41 | IKBKB | 1.12188060 |
42 | MAP3K10 | 1.11006796 |
43 | LCK | 1.09831191 |
44 | GRK6 | 1.09463204 |
45 | ITK | 1.06124101 |
46 | PINK1 | 1.05982781 |
47 | BMPR2 | 1.03642307 |
48 | JAK1 | 1.03155114 |
49 | LYN | 1.03132824 |
50 | MAP3K13 | 1.02093660 |
51 | TRPM7 | 0.96456510 |
52 | PIM1 | 0.93765804 |
53 | FRK | 0.93044073 |
54 | FGFR4 | 0.92970195 |
55 | STK10 | 0.92244257 |
56 | FLT3 | 0.89943841 |
57 | HIPK2 | 0.88585504 |
58 | YES1 | 0.88447046 |
59 | NEK9 | 0.87358226 |
60 | CAMKK2 | 0.86598003 |
61 | MAP4K2 | 0.86496135 |
62 | MAP3K6 | 0.85262421 |
63 | CHUK | 0.84726669 |
64 | HCK | 0.84049342 |
65 | JAK2 | 0.82352103 |
66 | MAP2K3 | 0.81219246 |
67 | CSK | 0.80737389 |
68 | NUAK1 | 0.77771611 |
69 | MAPK13 | 0.77227166 |
70 | TGFBR1 | 0.76116471 |
71 | MAPK11 | 0.75305774 |
72 | MAPK4 | 0.72827874 |
73 | BRD4 | 0.72471051 |
74 | PRKCQ | 0.71183838 |
75 | TAOK1 | 0.70865227 |
76 | NME1 | 0.70598904 |
77 | FES | 0.68292934 |
78 | ADRBK1 | 0.68047513 |
79 | FER | 0.67992958 |
80 | STK38 | 0.67418123 |
81 | KSR2 | 0.66099300 |
82 | EPHB1 | 0.65751837 |
83 | MAP3K8 | 0.65508698 |
84 | PRKG2 | 0.63635490 |
85 | CDK8 | 0.62425486 |
86 | MAP3K3 | 0.61303606 |
87 | CAMK1D | 0.60270175 |
88 | SGK2 | 0.59020022 |
89 | LMTK2 | 0.58397606 |
90 | STK11 | 0.58215290 |
91 | MAPK7 | 0.58161430 |
92 | MAP3K12 | 0.56605065 |
93 | TNIK | 0.56447599 |
94 | MST4 | 0.55713571 |
95 | GRK7 | 0.55636507 |
96 | ZAK | 0.55354967 |
97 | ERBB3 | 0.54369677 |
98 | TESK2 | 0.53938866 |
99 | STK4 | 0.53833817 |
100 | RPS6KA6 | 0.53260290 |
101 | MAP2K6 | 0.53070303 |
102 | NLK | 0.52805016 |
103 | EPHA3 | 0.52470470 |
104 | DAPK2 | 0.51607359 |
105 | MARK3 | 0.51502473 |
106 | RPS6KA2 | 0.47269589 |
107 | MYLK | 0.45908215 |
108 | CAMK1G | 0.45140583 |
109 | AKT3 | 0.45078510 |
110 | RPS6KC1 | 0.44744865 |
111 | RPS6KL1 | 0.44744865 |
112 | ABL1 | 0.44187761 |
113 | ADRBK2 | 0.43641388 |
114 | PDPK1 | 0.42500551 |
115 | RET | 0.41866379 |
116 | EIF2AK2 | 0.41256707 |
117 | ATR | 0.41253790 |
118 | CDK6 | 0.40595321 |
119 | IRAK1 | 0.39437663 |
120 | MAP2K1 | 0.39354607 |
121 | FYN | 0.37859002 |
122 | STK3 | 0.37300070 |
123 | PRKAA2 | 0.36351112 |
124 | EGFR | 0.36083522 |
125 | MAPKAPK2 | 0.35238972 |
126 | MARK2 | 0.34789861 |
127 | PDK1 | 0.34553578 |
128 | MAP3K4 | 0.33987931 |
129 | MAPK3 | 0.33834435 |
130 | PRKD2 | 0.33589023 |
131 | MAP3K1 | 0.33541587 |
132 | ALK | 0.32428888 |
133 | ERBB2 | 0.32201768 |
134 | RAF1 | 0.30123489 |
135 | SGK3 | 0.29223117 |
136 | ACVR1B | 0.28822871 |
137 | ERN1 | 0.27814954 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 2.82471234 |
2 | Mineral absorption_Homo sapiens_hsa04978 | 2.35374428 |
3 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.26789729 |
4 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.15128204 |
5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.07864820 |
6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.06996762 |
7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.03808382 |
8 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.99853190 |
9 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.99507343 |
10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.98600060 |
11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.91050266 |
12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.88706531 |
13 | Measles_Homo sapiens_hsa05162 | 1.87815950 |
14 | Other glycan degradation_Homo sapiens_hsa00511 | 1.76602662 |
15 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.72193992 |
16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.71563604 |
17 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.70274028 |
18 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.62842704 |
19 | Tuberculosis_Homo sapiens_hsa05152 | 1.60475125 |
20 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.60414403 |
21 | Pertussis_Homo sapiens_hsa05133 | 1.57804427 |
22 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.55445842 |
23 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.54930899 |
24 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.52614931 |
25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52173432 |
26 | * Influenza A_Homo sapiens_hsa05164 | 1.48048564 |
27 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.47990928 |
28 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.45250231 |
29 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.45171787 |
30 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.44719664 |
31 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.39386531 |
32 | Platelet activation_Homo sapiens_hsa04611 | 1.37563898 |
33 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.34085983 |
34 | Salmonella infection_Homo sapiens_hsa05132 | 1.32492726 |
35 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.30489243 |
36 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 1.29124117 |
37 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.27765633 |
38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.25764195 |
39 | * Herpes simplex infection_Homo sapiens_hsa05168 | 1.23638925 |
40 | Shigellosis_Homo sapiens_hsa05131 | 1.23200711 |
41 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.20373692 |
42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.19553065 |
43 | Hepatitis B_Homo sapiens_hsa05161 | 1.19204987 |
44 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.18780375 |
45 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.18319889 |
46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.17960614 |
47 | Apoptosis_Homo sapiens_hsa04210 | 1.17688425 |
48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.17438549 |
49 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.16324325 |
50 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.13610328 |
51 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.11523093 |
52 | * Hepatitis C_Homo sapiens_hsa05160 | 1.11424895 |
53 | Asthma_Homo sapiens_hsa05310 | 1.09886932 |
54 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.05302834 |
55 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.03994896 |
56 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.99697897 |
57 | Legionellosis_Homo sapiens_hsa05134 | 0.96285728 |
58 | Malaria_Homo sapiens_hsa05144 | 0.95330086 |
59 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.90481012 |
60 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.88963649 |
61 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.88044164 |
62 | Thyroid cancer_Homo sapiens_hsa05216 | 0.84193499 |
63 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.84130229 |
64 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.83925010 |
65 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.83087398 |
66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.82434364 |
67 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.81052825 |
68 | ABC transporters_Homo sapiens_hsa02010 | 0.80902203 |
69 | Allograft rejection_Homo sapiens_hsa05330 | 0.80775718 |
70 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.80654321 |
71 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.79258422 |
72 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.77535080 |
73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76268638 |
74 | Lysosome_Homo sapiens_hsa04142 | 0.74437224 |
75 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.73678486 |
76 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.72977547 |
77 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.72933825 |
78 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.70731347 |
79 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.70602913 |
80 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.67944764 |
81 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.66107965 |
82 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.64600841 |
83 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.62894489 |
84 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.61984136 |
85 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.61724929 |
86 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61318647 |
87 | Phagosome_Homo sapiens_hsa04145 | 0.60839533 |
88 | Bile secretion_Homo sapiens_hsa04976 | 0.60505140 |
89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.60227860 |
90 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.60101213 |
91 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59931946 |
92 | Phototransduction_Homo sapiens_hsa04744 | 0.59904524 |
93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59888881 |
94 | Insulin resistance_Homo sapiens_hsa04931 | 0.59131207 |
95 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.58351371 |
96 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.57606017 |
97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55972828 |
98 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.55943197 |
99 | Viral myocarditis_Homo sapiens_hsa05416 | 0.55598075 |
100 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.55348585 |
101 | Colorectal cancer_Homo sapiens_hsa05210 | 0.55056862 |
102 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.54834541 |
103 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.54224452 |
104 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.53339944 |
105 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.52397875 |
106 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.51795803 |
107 | Retinol metabolism_Homo sapiens_hsa00830 | 0.51573336 |
108 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.50605566 |
109 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.48592823 |
110 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48281282 |
111 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.47414413 |
112 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.47071145 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.46884465 |
114 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.45716741 |
115 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.44937253 |
116 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.43844435 |
117 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.43829802 |
118 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.43577820 |
119 | Salivary secretion_Homo sapiens_hsa04970 | 0.43405208 |
120 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.42779020 |
121 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.42681115 |
122 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.41871884 |
123 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.39289014 |
124 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.38905118 |
125 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.37760316 |
126 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.37179458 |
127 | HTLV-I infection_Homo sapiens_hsa05166 | 0.36942450 |
128 | Prostate cancer_Homo sapiens_hsa05215 | 0.36419423 |
129 | Pathways in cancer_Homo sapiens_hsa05200 | 0.36240638 |
130 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.35881901 |
131 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.35836488 |
132 | Adherens junction_Homo sapiens_hsa04520 | 0.34888707 |
133 | Endometrial cancer_Homo sapiens_hsa05213 | 0.34748065 |
134 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.33359173 |