RNF138

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synapsis (GO:0007129)4.62210149
2cell wall macromolecule catabolic process (GO:0016998)4.54666319
3cell wall macromolecule metabolic process (GO:0044036)4.54666319
4fusion of sperm to egg plasma membrane (GO:0007342)4.47781715
5ribosomal small subunit assembly (GO:0000028)4.41792029
6sperm-egg recognition (GO:0035036)4.39571661
7binding of sperm to zona pellucida (GO:0007339)4.35636159
8sperm motility (GO:0030317)4.31605035
9ribosome assembly (GO:0042255)4.08932461
10DNA deamination (GO:0045006)4.06899808
11maturation of SSU-rRNA (GO:0030490)4.06654774
12protein localization to kinetochore (GO:0034501)3.99052840
13piRNA metabolic process (GO:0034587)3.97938863
14cell-cell recognition (GO:0009988)3.92483603
15DNA replication initiation (GO:0006270)3.86982771
16spermatid development (GO:0007286)3.84743414
17acrosome assembly (GO:0001675)3.82897307
18DNA strand elongation involved in DNA replication (GO:0006271)3.78330267
19pore complex assembly (GO:0046931)3.75733832
20IMP biosynthetic process (GO:0006188)3.72037443
21DNA strand elongation (GO:0022616)3.69346228
22telomere maintenance via semi-conservative replication (GO:0032201)3.66807209
23negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.65098462
24negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.65098462
25negative regulation of mitotic sister chromatid segregation (GO:0033048)3.65098462
26negative regulation of mitotic sister chromatid separation (GO:2000816)3.65098462
27negative regulation of sister chromatid segregation (GO:0033046)3.65098462
28negative regulation of chromosome segregation (GO:0051985)3.62755917
29DNA double-strand break processing (GO:0000729)3.61634220
30establishment of integrated proviral latency (GO:0075713)3.59949817
31regulation of meiosis I (GO:0060631)3.59374852
32male meiosis (GO:0007140)3.57275402
33DNA synthesis involved in DNA repair (GO:0000731)3.57099982
34mitotic spindle checkpoint (GO:0071174)3.56320610
35synaptonemal complex assembly (GO:0007130)3.56062401
36spindle checkpoint (GO:0031577)3.53934576
37spindle assembly checkpoint (GO:0071173)3.50142504
38mitotic chromosome condensation (GO:0007076)3.49232863
39mitotic spindle assembly checkpoint (GO:0007094)3.46889994
40intra-S DNA damage checkpoint (GO:0031573)3.46822747
41DNA ligation (GO:0006266)3.45368844
42regulation of mitotic metaphase/anaphase transition (GO:0030071)3.43412797
43regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.43412797
44synaptonemal complex organization (GO:0070193)3.42152696
45regulation of mitotic spindle checkpoint (GO:1903504)3.41737190
46regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.41737190
47sister chromatid cohesion (GO:0007062)3.41481446
48negative regulation of DNA-dependent DNA replication (GO:2000104)3.41429931
49viral transcription (GO:0019083)3.40690563
50regulation of helicase activity (GO:0051095)3.40662204
51DNA replication checkpoint (GO:0000076)3.39587037
52regulation of mitotic sister chromatid segregation (GO:0033047)3.38583864
53regulation of sister chromatid segregation (GO:0033045)3.38583864
54regulation of mitotic sister chromatid separation (GO:0010965)3.38583864
55metaphase plate congression (GO:0051310)3.37872351
56chromatin remodeling at centromere (GO:0031055)3.37423798
57telomere maintenance via recombination (GO:0000722)3.37132697
58translational termination (GO:0006415)3.36587041
59kinetochore organization (GO:0051383)3.36441497
60axonemal dynein complex assembly (GO:0070286)3.35813310
61regulation of chromosome segregation (GO:0051983)3.34748791
62mitotic sister chromatid segregation (GO:0000070)3.34571074
63DNA replication-dependent nucleosome organization (GO:0034723)3.34101322
64DNA replication-dependent nucleosome assembly (GO:0006335)3.34101322
65purine nucleobase biosynthetic process (GO:0009113)3.32209697
66histone exchange (GO:0043486)3.32185183
67DNA catabolic process, exonucleolytic (GO:0000738)3.31904365
68nucleobase biosynthetic process (GO:0046112)3.31298323
69formation of translation preinitiation complex (GO:0001731)3.30355494
70sister chromatid segregation (GO:0000819)3.28794391
71acrosome reaction (GO:0007340)3.28553822
72regulation of DNA endoreduplication (GO:0032875)3.28269381
73nuclear pore organization (GO:0006999)3.24578184
74multicellular organism reproduction (GO:0032504)3.24354827
75ribosomal small subunit biogenesis (GO:0042274)3.23521998
76IMP metabolic process (GO:0046040)3.22485049
77resolution of meiotic recombination intermediates (GO:0000712)3.21442738
78DNA unwinding involved in DNA replication (GO:0006268)3.21343113
79DNA methylation involved in gamete generation (GO:0043046)3.20329428
80epithelial cilium movement (GO:0003351)3.20079805
81microtubule depolymerization (GO:0007019)3.18628015
82CENP-A containing nucleosome assembly (GO:0034080)3.17920255
83ribosome biogenesis (GO:0042254)3.17821165
84negative regulation of DNA recombination (GO:0045910)3.17602611
85mitotic recombination (GO:0006312)3.17525701
86centriole replication (GO:0007099)3.15565062
87regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.14515190
88plasma membrane fusion (GO:0045026)3.14020148
89nuclear pore complex assembly (GO:0051292)3.11847488
90ribonucleoprotein complex biogenesis (GO:0022613)3.10775445
91translational elongation (GO:0006414)3.10313149
92SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.09300201
93DNA replication-independent nucleosome organization (GO:0034724)3.09188930
94DNA replication-independent nucleosome assembly (GO:0006336)3.09188930
95non-recombinational repair (GO:0000726)3.07851479
96double-strand break repair via nonhomologous end joining (GO:0006303)3.07851479
97mitotic G2/M transition checkpoint (GO:0044818)3.07188818
98regulation of double-strand break repair via homologous recombination (GO:0010569)3.05917463
99meiotic nuclear division (GO:0007126)3.03262195
100male meiosis I (GO:0007141)3.02493822
101regulation of cilium movement (GO:0003352)3.02382015
102positive regulation of chromosome segregation (GO:0051984)3.01385666
103cotranslational protein targeting to membrane (GO:0006613)3.00901705
104meiotic chromosome segregation (GO:0045132)3.00320840
105ATP-dependent chromatin remodeling (GO:0043044)3.00139588
106protein targeting to ER (GO:0045047)2.99068849
107establishment of chromosome localization (GO:0051303)2.98685660
108RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.98087004
109nucleotide-excision repair, DNA gap filling (GO:0006297)2.98031676
110telomere maintenance via telomere lengthening (GO:0010833)2.97929110
111DNA topological change (GO:0006265)2.97280481
112negative regulation of mRNA processing (GO:0050686)2.97038068
113motile cilium assembly (GO:0044458)2.96072989
114spliceosomal snRNP assembly (GO:0000387)2.95978508
115chromosome organization involved in meiosis (GO:0070192)2.95744784
116regulation of centriole replication (GO:0046599)2.95728926
117nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.94185511
118single strand break repair (GO:0000012)2.92642319
119translational initiation (GO:0006413)2.92423291
120protein localization to chromosome (GO:0034502)2.92335867
121ribosomal large subunit biogenesis (GO:0042273)2.92059523
122negative regulation of RNA splicing (GO:0033119)2.92054936
123cilium or flagellum-dependent cell motility (GO:0001539)2.92051164
124DNA packaging (GO:0006323)2.91530098
125rRNA processing (GO:0006364)2.91403857
126mitotic nuclear envelope disassembly (GO:0007077)2.89185262
127negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.86582513
128kinetochore assembly (GO:0051382)2.86264804
129negative regulation of mRNA metabolic process (GO:1903312)2.85534452
130establishment of viral latency (GO:0019043)2.85511620
131protein localization to endoplasmic reticulum (GO:0070972)2.85406252
132regulation of nuclear cell cycle DNA replication (GO:0033262)2.84769836
133rRNA metabolic process (GO:0016072)2.83921283
134chromosome condensation (GO:0030261)2.81901720
135establishment of protein localization to endoplasmic reticulum (GO:0072599)2.80939341
136exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.79995727
137mitotic metaphase plate congression (GO:0007080)2.75184360
138mismatch repair (GO:0006298)2.74589381
139mitotic sister chromatid cohesion (GO:0007064)2.74254390
140reproduction (GO:0000003)2.73408654
141termination of RNA polymerase II transcription (GO:0006369)2.73266801
142regulation of histone H3-K9 methylation (GO:0051570)2.73087287
143transcription-coupled nucleotide-excision repair (GO:0006283)2.72424922
144histone H2A acetylation (GO:0043968)2.71922759
145somatic hypermutation of immunoglobulin genes (GO:0016446)2.71824170
146somatic diversification of immune receptors via somatic mutation (GO:0002566)2.71824170
147pseudouridine synthesis (GO:0001522)2.67600794
148membrane disassembly (GO:0030397)2.66809999
149nuclear envelope disassembly (GO:0051081)2.66809999
150cellular protein complex disassembly (GO:0043624)2.66380502
151viral life cycle (GO:0019058)2.66321103
152attachment of spindle microtubules to kinetochore (GO:0008608)2.65745317
153rRNA modification (GO:0000154)2.65059210
154nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.64740723
155protein K6-linked ubiquitination (GO:0085020)2.64455374
156protein localization to chromosome, centromeric region (GO:0071459)2.64261156
157nuclear-transcribed mRNA catabolic process (GO:0000956)2.64040091
158histone mRNA metabolic process (GO:0008334)2.63993987
159telomere maintenance (GO:0000723)2.62372588
160telomere organization (GO:0032200)2.61890722
161reciprocal meiotic recombination (GO:0007131)2.61756810
162reciprocal DNA recombination (GO:0035825)2.61756810

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.46267667
2MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse4.44932700
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.94533221
4* E2F4_17652178_ChIP-ChIP_JURKAT_Human3.13904324
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.75681407
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.73995255
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.73844269
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.71468824
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.69887369
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.63861115
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.62820276
12MYC_18358816_ChIP-ChIP_MESCs_Mouse2.61142631
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.60564737
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.44986099
15FOXM1_23109430_ChIP-Seq_U2OS_Human2.41220564
16* VDR_23849224_ChIP-Seq_CD4+_Human2.38829002
17ETS1_20019798_ChIP-Seq_JURKAT_Human2.37508641
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.34159294
19NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.29344841
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.23087428
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.17133701
22FOXP3_21729870_ChIP-Seq_TREG_Human2.05187177
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.02239882
24XRN2_22483619_ChIP-Seq_HELA_Human2.02029578
25CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.01898287
26SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.93243266
27SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.91544274
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.91148964
29TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.86578941
30MYCN_18555785_ChIP-Seq_MESCs_Mouse1.85397777
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.82703787
32PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.81254294
33FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.75694715
34DCP1A_22483619_ChIP-Seq_HELA_Human1.75661138
35HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.73870112
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.73021177
37GABP_19822575_ChIP-Seq_HepG2_Human1.72843269
38* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.70005390
39* TTF2_22483619_ChIP-Seq_HELA_Human1.69389315
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.65716758
41ELK1_19687146_ChIP-ChIP_HELA_Human1.64189370
42ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.64126084
43* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.62003379
44E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.60920224
45EWS_26573619_Chip-Seq_HEK293_Human1.58768556
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.57051954
47* E2F1_21310950_ChIP-Seq_MCF-7_Human1.56977567
48KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.56282494
49FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.55742329
50IGF1R_20145208_ChIP-Seq_DFB_Human1.54709489
51YY1_21170310_ChIP-Seq_MESCs_Mouse1.50142283
52IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.49571411
53SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.48166983
54ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.48022755
55CIITA_25753668_ChIP-Seq_RAJI_Human1.45576629
56AR_21909140_ChIP-Seq_LNCAP_Human1.43235222
57* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.43006877
58NANOG_18555785_ChIP-Seq_MESCs_Mouse1.40486960
59YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.40235259
60* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.40221490
61* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40050920
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.37005515
63RBPJ_22232070_ChIP-Seq_NCS_Mouse1.35381112
64PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.34829964
65FUS_26573619_Chip-Seq_HEK293_Human1.33450447
66THAP11_20581084_ChIP-Seq_MESCs_Mouse1.32702205
67TP63_19390658_ChIP-ChIP_HaCaT_Human1.28140281
68KDM5A_27292631_Chip-Seq_BREAST_Human1.23855701
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.22804327
70* MYC_22102868_ChIP-Seq_BL_Human1.19978052
71EGR1_19374776_ChIP-ChIP_THP-1_Human1.16630950
72DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13571480
73SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.09488918
74* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09448248
75SPI1_23547873_ChIP-Seq_NB4_Human1.09369624
76POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08203893
77IRF1_19129219_ChIP-ChIP_H3396_Human1.07895537
78HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.06089686
79RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.05277782
80KLF4_18555785_ChIP-Seq_MESCs_Mouse1.05170910
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05113813
82SCL_19346495_ChIP-Seq_HPC-7_Human1.03923515
83PADI4_21655091_ChIP-ChIP_MCF-7_Human1.03326167
84* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.02401750
85STAT3_1855785_ChIP-Seq_MESCs_Mouse0.99682366
86POU3F2_20337985_ChIP-ChIP_501MEL_Human0.97992397
87NANOG_16153702_ChIP-ChIP_HESCs_Human0.97724695
88MYB_26560356_Chip-Seq_TH2_Human0.97628464
89CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.96571592
90NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.95601968
91E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95532017
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94914531
93POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93954046
94HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.91962190
95SOX2_16153702_ChIP-ChIP_HESCs_Human0.91108384
96MYC_18940864_ChIP-ChIP_HL60_Human0.90446013
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.90356131
98* MYB_26560356_Chip-Seq_TH1_Human0.89211228
99FLI1_27457419_Chip-Seq_LIVER_Mouse0.88979977
100STAT4_19710469_ChIP-ChIP_TH1__Mouse0.84921891
101BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.82548990
102SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.82456797
103CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82334398
104CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.82204330
105MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.80916813
106KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.80109849
107KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.80109849
108KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.80109849
109TFEB_21752829_ChIP-Seq_HELA_Human0.79771237
110VDR_22108803_ChIP-Seq_LS180_Human0.79527288
111ZNF274_21170338_ChIP-Seq_K562_Hela0.78950586
112CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.78576394
113SALL1_21062744_ChIP-ChIP_HESCs_Human0.77495531

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005410_abnormal_fertilization4.89257115
2MP0003693_abnormal_embryo_hatching3.96120466
3MP0010094_abnormal_chromosome_stability3.85568330
4MP0008057_abnormal_DNA_replication3.85331514
5MP0008058_abnormal_DNA_repair3.68188694
6MP0004957_abnormal_blastocyst_morpholog3.43412404
7MP0008877_abnormal_DNA_methylation3.40746784
8MP0003111_abnormal_nucleus_morphology3.07019896
9MP0003077_abnormal_cell_cycle3.03980335
10MP0001929_abnormal_gametogenesis2.92106940
11MP0008007_abnormal_cellular_replicative2.76820289
12MP0003698_abnormal_male_reproductive2.52549603
13MP0002210_abnormal_sex_determination2.51829605
14MP0002396_abnormal_hematopoietic_system2.51406988
15MP0003763_abnormal_thymus_physiology2.37932850
16MP0001145_abnormal_male_reproductive2.14726201
17MP0003786_premature_aging2.01265660
18MP0000653_abnormal_sex_gland1.85150818
19MP0006292_abnormal_olfactory_placode1.81720499
20MP0008932_abnormal_embryonic_tissue1.79753490
21MP0000490_abnormal_crypts_of1.78208192
22MP0005671_abnormal_response_to1.77023040
23MP0005075_abnormal_melanosome_morpholog1.71179112
24MP0004808_abnormal_hematopoietic_stem1.68246951
25MP0006035_abnormal_mitochondrial_morpho1.63106557
26MP0000350_abnormal_cell_proliferation1.58576989
27MP0002398_abnormal_bone_marrow1.56769859
28MP0001730_embryonic_growth_arrest1.55814760
29MP0003123_paternal_imprinting1.55327725
30MP0009333_abnormal_splenocyte_physiolog1.53320506
31MP0002161_abnormal_fertility/fecundity1.48106898
32MP0000703_abnormal_thymus_morphology1.45840237
33MP0001293_anophthalmia1.40930833
34MP0002019_abnormal_tumor_incidence1.39299801
35MP0002160_abnormal_reproductive_system1.38254052
36MP0001188_hyperpigmentation1.34210061
37MP0003221_abnormal_cardiomyocyte_apopto1.30357656
38MP0000689_abnormal_spleen_morphology1.29304226
39MP0005174_abnormal_tail_pigmentation1.28993627
40MP0001545_abnormal_hematopoietic_system1.26920853
41MP0005397_hematopoietic_system_phenotyp1.26920853
42MP0002722_abnormal_immune_system1.26121449
43MP0000313_abnormal_cell_death1.25890341
44MP0002132_abnormal_respiratory_system1.22982477
45MP0010352_gastrointestinal_tract_polyps1.22808860
46MP0000716_abnormal_immune_system1.17584401
47MP0001835_abnormal_antigen_presentation1.17198707
48MP0001697_abnormal_embryo_size1.16844265
49MP0003890_abnormal_embryonic-extraembry1.15248925
50MP0002429_abnormal_blood_cell1.14494874
51MP0006036_abnormal_mitochondrial_physio1.14459838
52MP0001800_abnormal_humoral_immune1.14008568
53MP0008995_early_reproductive_senescence1.13157584
54MP0002277_abnormal_respiratory_mucosa1.11800623
55MP0005389_reproductive_system_phenotype1.11224888
56MP0002653_abnormal_ependyma_morphology1.10652496
57MP0002095_abnormal_skin_pigmentation1.08643667
58MP0002420_abnormal_adaptive_immunity1.08386440
59MP0000858_altered_metastatic_potential1.07739399
60MP0005380_embryogenesis_phenotype1.07479572
61MP0001672_abnormal_embryogenesis/_devel1.07479572
62MP0001819_abnormal_immune_cell1.06486192
63MP0002080_prenatal_lethality1.06254486
64MP0003718_maternal_effect1.05851589
65MP0001873_stomach_inflammation1.05333802
66MP0000685_abnormal_immune_system1.05221844
67MP0001119_abnormal_female_reproductive1.04299836
68MP0002405_respiratory_system_inflammati1.03704633
69MP0009672_abnormal_birth_weight1.03279553
70MP0002084_abnormal_developmental_patter1.01895451
71MP0002723_abnormal_immune_serum1.01872518
72MP0003315_abnormal_perineum_morphology1.00974160
73MP0004147_increased_porphyrin_level1.00848326
74MP0000465_gastrointestinal_hemorrhage1.00250470
75MP0002085_abnormal_embryonic_tissue1.00202869
76MP0003121_genomic_imprinting0.97606328
77MP0004133_heterotaxia0.96467338
78MP0001529_abnormal_vocalization0.95906999
79MP0009785_altered_susceptibility_to0.93949624
80MP0002166_altered_tumor_susceptibility0.93048518
81MP0000015_abnormal_ear_pigmentation0.92727977
82MP0009697_abnormal_copulation0.91443397
83MP0003984_embryonic_growth_retardation0.91394646
84MP0002452_abnormal_antigen_presenting0.89218717
85MP0002088_abnormal_embryonic_growth/wei0.89079482
86MP0002086_abnormal_extraembryonic_tissu0.88394040
87MP0003866_abnormal_defecation0.86638569
88MP0008260_abnormal_autophagy0.85745644
89MP0003806_abnormal_nucleotide_metabolis0.85536053
90MP0002102_abnormal_ear_morphology0.85271528
91MP0009703_decreased_birth_body0.81220043
92MP0001853_heart_inflammation0.80413092
93MP0002006_tumorigenesis0.80322469
94MP0003937_abnormal_limbs/digits/tail_de0.80146374
95MP0005000_abnormal_immune_tolerance0.80128434
96MP0003699_abnormal_female_reproductive0.80031248
97MP0004197_abnormal_fetal_growth/weight/0.79987757
98MP0001919_abnormal_reproductive_system0.79274697
99MP0010307_abnormal_tumor_latency0.79142904
100MP0003186_abnormal_redox_activity0.78064454
101MP0005025_abnormal_response_to0.76332479
102MP0006072_abnormal_retinal_apoptosis0.76136519
103MP0009379_abnormal_foot_pigmentation0.75278480
104MP0010155_abnormal_intestine_physiology0.75159767
105MP0003136_yellow_coat_color0.73512406
106MP0009278_abnormal_bone_marrow0.73088652
107MP0003787_abnormal_imprinting0.71830778
108MP0005084_abnormal_gallbladder_morpholo0.71640069
109MP0002009_preneoplasia0.71383345
110MP0005384_cellular_phenotype0.70666473
111MP0001286_abnormal_eye_development0.69807308
112MP0003119_abnormal_digestive_system0.68501878
113MP0002163_abnormal_gland_morphology0.68160248
114MP0008789_abnormal_olfactory_epithelium0.66849635
115MP0000358_abnormal_cell_content/0.66559552
116MP0003941_abnormal_skin_development0.66325907
117MP0000613_abnormal_salivary_gland0.66194380
118MP0001177_atelectasis0.65654898
119MP0003943_abnormal_hepatobiliary_system0.65183979
120MP0003656_abnormal_erythrocyte_physiolo0.64897334
121MP0003567_abnormal_fetal_cardiomyocyte0.64206834
122MP0001764_abnormal_homeostasis0.63835460
123MP0002075_abnormal_coat/hair_pigmentati0.61291752
124MP0005621_abnormal_cell_physiology0.58627765
125MP0004782_abnormal_surfactant_physiolog0.57231742

Predicted human phenotypes

RankGene SetZ-score
1Dynein arm defect of respiratory motile cilia (HP:0012255)5.20276187
2Absent/shortened dynein arms (HP:0200106)5.20276187
3Respiratory insufficiency due to defective ciliary clearance (HP:0200073)4.98675563
4Abnormal respiratory epithelium morphology (HP:0012253)4.19274098
5Abnormal respiratory motile cilium morphology (HP:0005938)4.19274098
6Birth length less than 3rd percentile (HP:0003561)4.08622776
7Abnormality of cells of the erythroid lineage (HP:0012130)4.04545081
8Abnormal number of erythroid precursors (HP:0012131)4.02817220
9Nasal polyposis (HP:0100582)3.81421358
10Abnormal respiratory motile cilium physiology (HP:0012261)3.77276339
11Volvulus (HP:0002580)3.64802859
12Reticulocytopenia (HP:0001896)3.40315439
13Aplastic anemia (HP:0001915)3.35983720
14Rhinitis (HP:0012384)3.32214561
15Breast hypoplasia (HP:0003187)3.24822807
16Chronic bronchitis (HP:0004469)3.12694495
17Abnormal spermatogenesis (HP:0008669)3.11501284
18Abnormality of the nasal mucosa (HP:0000433)3.11047359
19Abnormal ciliary motility (HP:0012262)3.08254650
20Embryonal renal neoplasm (HP:0011794)3.01438341
2111 pairs of ribs (HP:0000878)2.98472029
22Abnormality of the labia minora (HP:0012880)2.96355794
23Supernumerary spleens (HP:0009799)2.93317879
24Bronchitis (HP:0012387)2.93007951
25Degeneration of anterior horn cells (HP:0002398)2.88233396
26Abnormality of the anterior horn cell (HP:0006802)2.88233396
27Rhabdomyosarcoma (HP:0002859)2.83657416
28Oral leukoplakia (HP:0002745)2.80625086
29Recurrent bronchitis (HP:0002837)2.79883588
30Bronchiectasis (HP:0002110)2.73377856
31Myelodysplasia (HP:0002863)2.64474035
32Medulloblastoma (HP:0002885)2.61918920
33Infertility (HP:0000789)2.61870404
34Abnormality of the preputium (HP:0100587)2.61608021
35Aplasia/Hypoplasia of the uvula (HP:0010293)2.61103892
36Type 2 muscle fiber atrophy (HP:0003554)2.60905603
37Abnormality of chromosome stability (HP:0003220)2.60703453
38Colon cancer (HP:0003003)2.57609356
39Muscle fiber atrophy (HP:0100295)2.53798132
40Microvesicular hepatic steatosis (HP:0001414)2.51861455
41IgM deficiency (HP:0002850)2.51517250
42Meckel diverticulum (HP:0002245)2.51365423
43Type I transferrin isoform profile (HP:0003642)2.49303674
44Pallor (HP:0000980)2.43650266
45Abnormality of the ileum (HP:0001549)2.39919019
46Chromsome breakage (HP:0040012)2.35839532
47Patellar aplasia (HP:0006443)2.35416157
48Absent thumb (HP:0009777)2.33203100
49Premature graying of hair (HP:0002216)2.32745526
50Macrocytic anemia (HP:0001972)2.31723610
51Impulsivity (HP:0100710)2.30359388
52Thrombocytosis (HP:0001894)2.29956940
53Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.29439088
54Short middle phalanx of the 5th finger (HP:0004220)2.25309777
55Gonadotropin excess (HP:0000837)2.24765336
56Neoplasm of the colon (HP:0100273)2.24659436
57Ectopic kidney (HP:0000086)2.24284523
58Selective tooth agenesis (HP:0001592)2.22434606
59Aplasia/Hypoplasia of the patella (HP:0006498)2.21788377
60Bone marrow hypocellularity (HP:0005528)2.20035742
61Absent radius (HP:0003974)2.19914109
62Combined immunodeficiency (HP:0005387)2.19561531
63Chromosomal breakage induced by crosslinking agents (HP:0003221)2.18737874
64Pancreatic islet-cell hyperplasia (HP:0004510)2.16573265
65Recurrent sinusitis (HP:0011108)2.15423246
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.15228660
67Abnormal protein N-linked glycosylation (HP:0012347)2.15228660
68Abnormal protein glycosylation (HP:0012346)2.15228660
69Abnormal glycosylation (HP:0012345)2.15228660
70Abnormal lung lobation (HP:0002101)2.12407569
71Sloping forehead (HP:0000340)2.11519006
72Lymphoma (HP:0002665)2.09914905
73Small intestinal stenosis (HP:0012848)2.08446206
74Duodenal stenosis (HP:0100867)2.08446206
75Microretrognathia (HP:0000308)2.06821180
76Pancytopenia (HP:0001876)2.04953083
77Embryonal neoplasm (HP:0002898)2.04595072
78Rough bone trabeculation (HP:0100670)2.04565633
79T lymphocytopenia (HP:0005403)2.04235801
80Aplasia involving forearm bones (HP:0009822)2.04014537
81Absent forearm bone (HP:0003953)2.04014537
82IgG deficiency (HP:0004315)2.04002168
83Cleft eyelid (HP:0000625)2.03588775
84Multiple enchondromatosis (HP:0005701)2.02599080
85Abnormality of DNA repair (HP:0003254)1.99099635
86Basal cell carcinoma (HP:0002671)1.99059756
87Azoospermia (HP:0000027)1.95674976
88Agnosia (HP:0010524)1.94931041
89Acute lymphatic leukemia (HP:0006721)1.94257488
90Asplenia (HP:0001746)1.93147698
91Biliary tract neoplasm (HP:0100574)1.92374303
92Abnormality of T cells (HP:0002843)1.90388841
93Clubbing of toes (HP:0100760)1.90282382
94Increased nuchal translucency (HP:0010880)1.90162233
95Abnormality of methionine metabolism (HP:0010901)1.90119416
96Neoplasm of the small intestine (HP:0100833)1.89243455
97Cerebral hypomyelination (HP:0006808)1.89001172
98Facial cleft (HP:0002006)1.88977335
99Optic nerve coloboma (HP:0000588)1.88865049
100Carpal bone hypoplasia (HP:0001498)1.86836144
101Ovarian neoplasm (HP:0100615)1.86780471
102Cafe-au-lait spot (HP:0000957)1.86698107
103Neoplasm of the pancreas (HP:0002894)1.86408968
104Nephronophthisis (HP:0000090)1.86114078
105Abnormality of T cell number (HP:0011839)1.85659115
106Atrophy/Degeneration involving motor neurons (HP:0007373)1.85560914
107Decreased activity of mitochondrial respiratory chain (HP:0008972)1.83809901
108Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.83809901
109Reduced antithrombin III activity (HP:0001976)1.83765381
110Tubulointerstitial nephritis (HP:0001970)1.82550435
111Triphalangeal thumb (HP:0001199)1.82141816
112Cortical dysplasia (HP:0002539)1.81766990
113Panhypogammaglobulinemia (HP:0003139)1.81462495
114Amaurosis fugax (HP:0100576)1.80462139
115Severe combined immunodeficiency (HP:0004430)1.78790074
116Nephroblastoma (Wilms tumor) (HP:0002667)1.78037834
117Abnormality of the duodenum (HP:0002246)1.77854141
118B lymphocytopenia (HP:0010976)1.76842271
119Missing ribs (HP:0000921)1.76821339
120Pulmonary fibrosis (HP:0002206)1.76478079
121Aplasia/Hypoplasia of the spleen (HP:0010451)1.75251661
122Methylmalonic acidemia (HP:0002912)1.75000433
123Hypoplasia of the radius (HP:0002984)1.74645444
124Acute myeloid leukemia (HP:0004808)1.74581107
125Shoulder girdle muscle weakness (HP:0003547)1.73993976
126Pancreatic fibrosis (HP:0100732)1.73867279
127Recurrent otitis media (HP:0000403)1.73734597
128Duplicated collecting system (HP:0000081)1.73266064
129Ependymoma (HP:0002888)1.72974531
130Dyschromatopsia (HP:0007641)1.72642042
131Horseshoe kidney (HP:0000085)1.71823494
132Stenosis of the external auditory canal (HP:0000402)1.71289432
133Abnormality of homocysteine metabolism (HP:0010919)1.70796376
134Homocystinuria (HP:0002156)1.70796376
135Breast carcinoma (HP:0003002)1.70398806
136Papillary thyroid carcinoma (HP:0002895)1.70382439
137Chronic otitis media (HP:0000389)1.69033746
138Abnormality of B cell number (HP:0010975)1.67753454
139Abnormality of the renal collecting system (HP:0004742)1.66259514
140Neoplasm of striated muscle (HP:0009728)1.65903767
141Progressive external ophthalmoplegia (HP:0000590)1.62843182
142Abnormal hair whorl (HP:0010721)1.62225161
143Oligodactyly (hands) (HP:0001180)1.62169645
144Cellular immunodeficiency (HP:0005374)1.60609330
145Choanal atresia (HP:0000453)1.60439950
146Aplasia/Hypoplasia of the earlobes (HP:0009906)1.60014258
147Abnormality of chromosome segregation (HP:0002916)1.59936296
148Abnormality of the carotid arteries (HP:0005344)1.59830782
149Scotoma (HP:0000575)1.58194389
150Abnormality of the prostate (HP:0008775)1.56819276
151Abnormality of aspartate family amino acid metabolism (HP:0010899)1.56619186
152Abnormality of the pons (HP:0007361)1.54455826
153Glioma (HP:0009733)1.54389457

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE13.73115516
2PDK33.31933585
3PDK43.31933585
4STK162.93378697
5BUB12.93331508
6CDC72.72299822
7DYRK32.66328044
8ACVR1B2.63668263
9SRPK12.62043505
10EIF2AK12.55669338
11BRSK22.28524448
12PASK2.25561432
13TRIM282.06803810
14PDK22.05012034
15PLK42.04637978
16NEK22.04064184
17NUAK12.03852309
18TESK12.02216538
19TSSK61.92919346
20VRK11.85737818
21EIF2AK31.85055271
22MKNK11.75119374
23TXK1.68846466
24RPS6KA41.60376659
25PBK1.58810619
26TEC1.58563606
27TLK11.57585892
28CCNB11.56395815
29ATR1.56264295
30CDK71.51345747
31MKNK21.50777921
32PLK11.48855610
33NME21.46568026
34BRSK11.42422643
35TGFBR11.42074601
36VRK21.39448560
37FLT31.36667820
38MAP4K11.35849829
39RPS6KB21.35161404
40TAF11.27611228
41CHEK21.26112702
42TTK1.22327159
43MAP3K101.22090234
44BRD41.21190353
45BTK1.13345714
46MST41.11975181
47TESK21.09190484
48NLK1.08367434
49BCR1.08215420
50AURKB1.04598688
51PIM11.03221585
52TNIK1.00748849
53KIT1.00222758
54CDK120.99600703
55STK30.99414057
56CHEK10.96760471
57IRAK40.95428552
58MAP3K140.94641361
59STK100.94002836
60CDK40.91957410
61ITK0.88470200
62ZAP700.84812095
63STK240.83443903
64PLK30.82704810
65CDK60.82651894
66ATM0.80683319
67YES10.80179226
68DYRK20.79692090
69AURKA0.76100628
70WNK30.73963335
71ALK0.72493784
72JAK30.72094580
73CSNK1G10.68943900
74CSNK2A10.67821234
75CDK80.67541352
76BMPR20.67004501
77PAK40.64193545
78CSNK2A20.63497165
79CDK30.62471805
80PIM20.61868641
81MELK0.61615070
82STK38L0.60719751
83CSF1R0.60332121
84CDK20.59800660
85RAF10.57773064
86IKBKB0.57452017
87CDK190.57217767
88BMPR1B0.56984455
89BCKDK0.56234855
90NEK10.53826868
91EEF2K0.53318459
92RPS6KA50.52757091
93MAP3K80.52344422
94LCK0.50354419
95EIF2AK20.49900686
96OXSR10.49875798
97CSNK1G30.49281719
98SCYL20.48662078
99DYRK1B0.48311090
100CSNK1G20.47922876
101PLK20.47183471
102MAP2K60.46424930
103KDR0.45765074
104MATK0.44745247
105MAP3K40.44672371
106CHUK0.44630004
107CLK10.44066272
108MUSK0.43837782
109ERBB30.43655864
110EPHA20.43056146
111ZAK0.40695153
112IRAK10.40404115
113IKBKE0.39686161
114CSNK1A1L0.39050703
115CDK10.37941079
116RPS6KB10.37112717
117BRAF0.36957254
118IRAK20.34999816
119ICK0.34737775
120NEK60.34083318
121TGFBR20.32998074
122PRKD30.32855413
123SYK0.32369096
124MARK30.32172372
125EGFR0.30866723
126STK40.30828627
127CDK90.30192147
128PRKDC0.29992006
129MAPKAPK30.28728696
130RPS6KA60.28170836
131MAP3K50.27765261
132PNCK0.27763357
133MAPK150.26540862
134LATS10.26382090

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.58069668
2Mismatch repair_Homo sapiens_hsa034303.83095081
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.59381748
4Ribosome_Homo sapiens_hsa030103.47484072
5Spliceosome_Homo sapiens_hsa030403.28005979
6RNA polymerase_Homo sapiens_hsa030203.06391854
7Base excision repair_Homo sapiens_hsa034102.99599375
8RNA transport_Homo sapiens_hsa030132.91716671
9Homologous recombination_Homo sapiens_hsa034402.88149000
10Proteasome_Homo sapiens_hsa030502.79423910
11Basal transcription factors_Homo sapiens_hsa030222.78761735
12Nucleotide excision repair_Homo sapiens_hsa034202.73015797
13Fanconi anemia pathway_Homo sapiens_hsa034602.51760762
14Pyrimidine metabolism_Homo sapiens_hsa002402.49284662
15Cell cycle_Homo sapiens_hsa041102.34459329
16RNA degradation_Homo sapiens_hsa030182.22460663
17Non-homologous end-joining_Homo sapiens_hsa034502.13836995
18mRNA surveillance pathway_Homo sapiens_hsa030151.86120443
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.85852819
20Protein export_Homo sapiens_hsa030601.81124016
21Antigen processing and presentation_Homo sapiens_hsa046121.77439096
22One carbon pool by folate_Homo sapiens_hsa006701.70857018
23Primary immunodeficiency_Homo sapiens_hsa053401.66535008
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.63322677
25Purine metabolism_Homo sapiens_hsa002301.51998396
26Herpes simplex infection_Homo sapiens_hsa051681.34808635
27p53 signaling pathway_Homo sapiens_hsa041151.27458264
28Epstein-Barr virus infection_Homo sapiens_hsa051691.27375155
29Propanoate metabolism_Homo sapiens_hsa006401.23890365
30Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.22208163
31Selenocompound metabolism_Homo sapiens_hsa004501.14137037
32Measles_Homo sapiens_hsa051621.04491839
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.02824716
34Vitamin B6 metabolism_Homo sapiens_hsa007500.94468127
35Systemic lupus erythematosus_Homo sapiens_hsa053220.93919981
36Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.83280528
37Oocyte meiosis_Homo sapiens_hsa041140.81468108
38Viral carcinogenesis_Homo sapiens_hsa052030.79681816
39N-Glycan biosynthesis_Homo sapiens_hsa005100.79196738
40Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.77367594
41Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.74861097
42Legionellosis_Homo sapiens_hsa051340.74007863
43Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73456123
44Cysteine and methionine metabolism_Homo sapiens_hsa002700.72437932
45Transcriptional misregulation in cancer_Homo sapiens_hsa052020.71506821
46Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.71467873
47HTLV-I infection_Homo sapiens_hsa051660.70518404
48NF-kappa B signaling pathway_Homo sapiens_hsa040640.70485594
49Graft-versus-host disease_Homo sapiens_hsa053320.70474903
50Parkinsons disease_Homo sapiens_hsa050120.69241000
51T cell receptor signaling pathway_Homo sapiens_hsa046600.67978307
52Pentose phosphate pathway_Homo sapiens_hsa000300.67550281
53Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.67155537
54Steroid biosynthesis_Homo sapiens_hsa001000.66108555
55Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.63716285
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60086852
57Folate biosynthesis_Homo sapiens_hsa007900.57695964
58Influenza A_Homo sapiens_hsa051640.57513615
59RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.57021238
60Linoleic acid metabolism_Homo sapiens_hsa005910.56799145
61Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.56752128
62Hematopoietic cell lineage_Homo sapiens_hsa046400.55319962
63Intestinal immune network for IgA production_Homo sapiens_hsa046720.53755749
64Carbon metabolism_Homo sapiens_hsa012000.52287134
65Allograft rejection_Homo sapiens_hsa053300.52258479
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.50160176
67Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49004484
68Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.48692877
69Huntingtons disease_Homo sapiens_hsa050160.47815176
70Fatty acid elongation_Homo sapiens_hsa000620.46668815
71Shigellosis_Homo sapiens_hsa051310.45764157
72Jak-STAT signaling pathway_Homo sapiens_hsa046300.45761467
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.44016066
74Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43664563
75Notch signaling pathway_Homo sapiens_hsa043300.43255761
762-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.42925711
77Acute myeloid leukemia_Homo sapiens_hsa052210.41867738
78Hepatitis B_Homo sapiens_hsa051610.40959943
79Thyroid cancer_Homo sapiens_hsa052160.39763333
80alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.39348783
81Glutathione metabolism_Homo sapiens_hsa004800.37168489
82Regulation of autophagy_Homo sapiens_hsa041400.37071209
83Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.36378998
84Colorectal cancer_Homo sapiens_hsa052100.35651296
85NOD-like receptor signaling pathway_Homo sapiens_hsa046210.35081498
86Oxidative phosphorylation_Homo sapiens_hsa001900.34841925
87Arachidonic acid metabolism_Homo sapiens_hsa005900.33585235
88B cell receptor signaling pathway_Homo sapiens_hsa046620.33196333
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.32573843
90Maturity onset diabetes of the young_Homo sapiens_hsa049500.31880634
91Sulfur relay system_Homo sapiens_hsa041220.31121518
92Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.29656649
93Small cell lung cancer_Homo sapiens_hsa052220.29126469
94Cyanoamino acid metabolism_Homo sapiens_hsa004600.28535676
95Biosynthesis of amino acids_Homo sapiens_hsa012300.28090832
96Type I diabetes mellitus_Homo sapiens_hsa049400.27310857
97Asthma_Homo sapiens_hsa053100.26063080
98Apoptosis_Homo sapiens_hsa042100.25383899
99Circadian rhythm_Homo sapiens_hsa047100.24987060
100Alcoholism_Homo sapiens_hsa050340.24471072
101Autoimmune thyroid disease_Homo sapiens_hsa053200.24215761
102Metabolic pathways_Homo sapiens_hsa011000.22516303
103Pancreatic cancer_Homo sapiens_hsa052120.18977833
104Peroxisome_Homo sapiens_hsa041460.18735633
105Viral myocarditis_Homo sapiens_hsa054160.18570223
106Olfactory transduction_Homo sapiens_hsa047400.17852147
107Caffeine metabolism_Homo sapiens_hsa002320.16454247
108Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.15742871
109Chronic myeloid leukemia_Homo sapiens_hsa052200.14860343
110TGF-beta signaling pathway_Homo sapiens_hsa043500.14624756
111Fructose and mannose metabolism_Homo sapiens_hsa000510.14552962
112Toxoplasmosis_Homo sapiens_hsa051450.14175853
113Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.13302899
114Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.13129949
115MicroRNAs in cancer_Homo sapiens_hsa052060.13093193
116Pyruvate metabolism_Homo sapiens_hsa006200.12208189
117Leishmaniasis_Homo sapiens_hsa051400.11260696
118Ether lipid metabolism_Homo sapiens_hsa005650.09953755
119Prostate cancer_Homo sapiens_hsa052150.09339019
120Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.08241625
121Other glycan degradation_Homo sapiens_hsa005110.08229617

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