RNF150

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)4.64352932
2positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.43449725
3vocalization behavior (GO:0071625)4.41372744
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.30684331
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.27408179
6synaptic vesicle exocytosis (GO:0016079)4.21666344
7protein localization to synapse (GO:0035418)4.14195546
8ionotropic glutamate receptor signaling pathway (GO:0035235)4.09150991
9neuron cell-cell adhesion (GO:0007158)4.06772562
10locomotory exploration behavior (GO:0035641)4.03337615
11synaptic vesicle maturation (GO:0016188)3.99535377
12glutamate receptor signaling pathway (GO:0007215)3.96878169
13neuronal action potential propagation (GO:0019227)3.96498795
14regulation of glutamate receptor signaling pathway (GO:1900449)3.90917933
15regulation of skeletal muscle contraction (GO:0014819)3.86443517
16cardiac myofibril assembly (GO:0055003)3.68262785
17regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.65808506
18regulation of synaptic vesicle exocytosis (GO:2000300)3.62912049
19neuron-neuron synaptic transmission (GO:0007270)3.62231559
20glutamate secretion (GO:0014047)3.61752007
21myofibril assembly (GO:0030239)3.55069662
22neuron recognition (GO:0008038)3.52731269
23regulation of membrane repolarization (GO:0060306)3.51234275
24synaptic transmission, glutamatergic (GO:0035249)3.50526319
25otic vesicle formation (GO:0030916)3.50370820
26regulation of long-term neuronal synaptic plasticity (GO:0048169)3.49997510
27regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)3.49599623
28regulation of excitatory postsynaptic membrane potential (GO:0060079)3.47448184
29muscle filament sliding (GO:0030049)3.45734053
30actin-myosin filament sliding (GO:0033275)3.45734053
31regulation of synapse structural plasticity (GO:0051823)3.45714925
32axonal fasciculation (GO:0007413)3.43398135
33dendritic spine morphogenesis (GO:0060997)3.42473898
34relaxation of cardiac muscle (GO:0055119)3.42324530
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.38830795
36regulation of postsynaptic membrane potential (GO:0060078)3.34836473
37synaptic vesicle docking involved in exocytosis (GO:0016081)3.34720910
38gamma-aminobutyric acid signaling pathway (GO:0007214)3.34607569
39membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.33425488
40G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.32642804
41transmission of nerve impulse (GO:0019226)3.32565020
42sarcomere organization (GO:0045214)3.31658199
43long-term memory (GO:0007616)3.31186790
44regulation of neuronal synaptic plasticity (GO:0048168)3.31102716
45synaptic vesicle endocytosis (GO:0048488)3.30073705
46regulation of synaptic vesicle transport (GO:1902803)3.28793798
47adult heart development (GO:0007512)3.28702513
48positive regulation of cardiac muscle cell differentiation (GO:2000727)3.28047508
49presynaptic membrane assembly (GO:0097105)3.26526760
50positive regulation of potassium ion transmembrane transport (GO:1901381)3.24571074
51exploration behavior (GO:0035640)3.24130408
52detection of calcium ion (GO:0005513)3.21245860
53regulation of dendritic spine morphogenesis (GO:0061001)3.18136199
54cellular potassium ion homeostasis (GO:0030007)3.16464127
55sarcoplasmic reticulum calcium ion transport (GO:0070296)3.12613217
56cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.10356561
57sulfation (GO:0051923)3.09421055
58negative regulation of synaptic transmission, GABAergic (GO:0032229)3.09391121
59long-term synaptic potentiation (GO:0060291)3.09166796
60behavioral response to cocaine (GO:0048148)3.09057705
61cardiac muscle hypertrophy (GO:0003300)3.07145620
62layer formation in cerebral cortex (GO:0021819)3.06154198
63response to histamine (GO:0034776)3.04751998
64regulation of voltage-gated calcium channel activity (GO:1901385)3.04203823
65presynaptic membrane organization (GO:0097090)3.04073941
66activation of protein kinase A activity (GO:0034199)3.03467360
67striated muscle hypertrophy (GO:0014897)3.02667995
68behavioral fear response (GO:0001662)3.01064092
69behavioral defense response (GO:0002209)3.01064092
70actin-mediated cell contraction (GO:0070252)3.01007981
71striatum development (GO:0021756)3.00901960
72positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)2.99283339
73regulation of synaptic plasticity (GO:0048167)2.98643489
74synaptic transmission, dopaminergic (GO:0001963)2.97615950
75negative regulation of potassium ion transmembrane transporter activity (GO:1901017)2.97234079
76cell migration involved in heart development (GO:0060973)2.95783004
77neurotransmitter secretion (GO:0007269)2.95497178
78positive regulation of membrane potential (GO:0045838)2.95327041
79innervation (GO:0060384)2.94376236
80cartilage morphogenesis (GO:0060536)2.94284551
81cardiac chamber formation (GO:0003207)2.93855345
82regulation of synaptic transmission, glutamatergic (GO:0051966)2.91838588
83cell proliferation in forebrain (GO:0021846)2.90358525
84regulation of dendritic spine development (GO:0060998)2.90295310
85membrane depolarization (GO:0051899)2.89561669
86cardiac ventricle formation (GO:0003211)2.89394123
87regulation of actin filament-based movement (GO:1903115)2.87132950
88regulation of vesicle fusion (GO:0031338)2.86231932
89cardiac muscle cell action potential (GO:0086001)2.86172304
90neurotransmitter-gated ion channel clustering (GO:0072578)2.84486684
91positive regulation of neurotransmitter transport (GO:0051590)2.83989279
92mating behavior (GO:0007617)2.83913211
93cardiac muscle contraction (GO:0060048)2.83758784
94cerebellar Purkinje cell differentiation (GO:0021702)2.83592374
95fear response (GO:0042596)2.83571219
96membrane depolarization during action potential (GO:0086010)2.83200235
97retinal ganglion cell axon guidance (GO:0031290)2.82462776
98long term synaptic depression (GO:0060292)2.82083027
99regulation of neurotransmitter secretion (GO:0046928)2.82036278
100L-amino acid import (GO:0043092)2.81234295
101positive regulation of neurotransmitter secretion (GO:0001956)2.80543683
102limb bud formation (GO:0060174)2.79674660
103positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.79003517
104dendrite morphogenesis (GO:0048813)2.78700984
105neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.78624754
106membrane hyperpolarization (GO:0060081)2.78420459
107regulation of cell communication by electrical coupling (GO:0010649)2.77349022
108regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.76744705
109regulation of relaxation of muscle (GO:1901077)2.74675042
110G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.74167256
111dentate gyrus development (GO:0021542)2.73594849
112positive regulation of potassium ion transport (GO:0043268)2.72898690
113cell communication by electrical coupling (GO:0010644)2.72455154
114positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.71777903
115cardiac muscle cell action potential involved in contraction (GO:0086002)2.71073905
116startle response (GO:0001964)2.69913603
117negative regulation of potassium ion transmembrane transport (GO:1901380)2.69879573
118regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)2.69773956
119learning (GO:0007612)2.69381306
120relaxation of muscle (GO:0090075)2.69075570
121regulation of cardioblast proliferation (GO:0003264)2.68086116
122regulation of secondary heart field cardioblast proliferation (GO:0003266)2.68086116
123regulation of glutamate secretion (GO:0014048)2.67978580
124chemosensory behavior (GO:0007635)2.66239570
125negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.66033532
126cardiac conduction (GO:0061337)2.64969164
127negative regulation of cytosolic calcium ion concentration (GO:0051481)2.64899728
128muscle hypertrophy (GO:0014896)2.63022713
129response to auditory stimulus (GO:0010996)2.62894360
130positive regulation of synapse maturation (GO:0090129)2.61716502
131auditory behavior (GO:0031223)2.61353931
132negative chemotaxis (GO:0050919)2.60670176
133smooth muscle tissue development (GO:0048745)2.60485881
134cell communication involved in cardiac conduction (GO:0086065)2.60454092
135neurotransmitter transport (GO:0006836)2.60216170
136synapse assembly (GO:0007416)2.60018850
137regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO2.60007471
138regulation of neurotransmitter transport (GO:0051588)2.59892816
139postsynaptic membrane organization (GO:0001941)2.58847025
140ventricular cardiac muscle cell action potential (GO:0086005)2.58813331
141regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.58599229
142dendritic spine organization (GO:0097061)2.58388786
143neuromuscular process controlling balance (GO:0050885)2.57867268
144regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.57574744
145regulation of potassium ion transmembrane transport (GO:1901379)2.57453817
146vesicle transport along microtubule (GO:0047496)2.57447463
147adult walking behavior (GO:0007628)2.56974131
148regulation of calcium ion transmembrane transport (GO:1903169)2.56788776
149regulation of calcium ion transmembrane transporter activity (GO:1901019)2.56788776
150striated muscle contraction (GO:0006941)2.56600684
151somite development (GO:0061053)2.55602205
152metanephric mesenchyme development (GO:0072075)2.54636773
153artery development (GO:0060840)2.53725057
154multicellular organismal signaling (GO:0035637)2.53139691
155negative regulation of cardiac muscle cell apoptotic process (GO:0010667)2.52836660
156regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.52580210
157pharyngeal system development (GO:0060037)2.52331211
158myelination in peripheral nervous system (GO:0022011)2.51391617
159peripheral nervous system axon ensheathment (GO:0032292)2.51391617
160regulation of striated muscle contraction (GO:0006942)2.47858252
161epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.46482274
162actomyosin structure organization (GO:0031032)2.46368739
163regulation of cardiac muscle cell differentiation (GO:2000725)2.46277259
164dermatan sulfate biosynthetic process (GO:0030208)2.45364327
165cardiac muscle cell development (GO:0055013)2.41676891
166regulation of heart rate (GO:0002027)2.40701262
167response to inactivity (GO:0014854)2.40537704
168lymphangiogenesis (GO:0001946)2.37058095
169regulation of axon extension involved in axon guidance (GO:0048841)2.35980264
170response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.35827700
171regulation of axon guidance (GO:1902667)2.34800326
172membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.34125793
173regulation of glomerulus development (GO:0090192)2.32198202
174regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.32091229
175neuron remodeling (GO:0016322)2.31587825
176prostate gland growth (GO:0060736)2.31439716
177negative regulation of protein localization to cell surface (GO:2000009)2.31144861
178interkinetic nuclear migration (GO:0022027)2.31119142
179regulation of heart rate by cardiac conduction (GO:0086091)2.30949535
180gamma-aminobutyric acid transport (GO:0015812)2.30729997
181lateral sprouting from an epithelium (GO:0060601)2.29140628

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.03306370
2* GBX2_23144817_ChIP-Seq_PC3_Human3.76088108
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.92572698
4* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.90764937
5* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.90603181
6* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.58647895
7* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.58647895
8* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.53594645
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.43099094
10* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41616762
11SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.41223742
12* EZH2_27304074_Chip-Seq_ESCs_Mouse2.33873720
13* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.33837510
14DROSHA_22980978_ChIP-Seq_HELA_Human2.29915367
15* EED_16625203_ChIP-ChIP_MESCs_Mouse2.28013868
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.23754635
17RNF2_27304074_Chip-Seq_ESCs_Mouse2.03201822
18FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.01926026
19REST_21632747_ChIP-Seq_MESCs_Mouse2.01256207
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.00072692
21SUZ12_27294783_Chip-Seq_ESCs_Mouse1.99505468
22RARB_27405468_Chip-Seq_BRAIN_Mouse1.99123041
23TAF15_26573619_Chip-Seq_HEK293_Human1.96055371
24RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.94512081
25GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.80881518
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.75756000
27IKZF1_21737484_ChIP-ChIP_HCT116_Human1.74533011
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.71987201
29RBPJ_22232070_ChIP-Seq_NCS_Mouse1.71207806
30* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.71040980
31SMAD4_21799915_ChIP-Seq_A2780_Human1.70915555
32ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.69238960
33* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.68430754
34CDX2_19796622_ChIP-Seq_MESCs_Mouse1.67300086
35* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.66630894
36AR_21572438_ChIP-Seq_LNCaP_Human1.65602509
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.64831829
38HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.62240124
39SMAD_19615063_ChIP-ChIP_OVARY_Human1.59278291
40P300_19829295_ChIP-Seq_ESCs_Human1.55599016
41* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51312334
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.49477139
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.48842481
44PIAS1_25552417_ChIP-Seq_VCAP_Human1.47744060
45* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.45228195
46* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.45211834
47SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.43084683
48EWS_26573619_Chip-Seq_HEK293_Human1.41895638
49* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41497464
50NR3C1_23031785_ChIP-Seq_PC12_Mouse1.40026635
51VDR_22108803_ChIP-Seq_LS180_Human1.38826623
52POU3F2_20337985_ChIP-ChIP_501MEL_Human1.37330102
53ZNF217_24962896_ChIP-Seq_MCF-7_Human1.35139801
54SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34686208
55TP53_16413492_ChIP-PET_HCT116_Human1.34390195
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34374065
57TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34041545
58BMI1_23680149_ChIP-Seq_NPCS_Mouse1.33906120
59OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33566054
60CBX2_27304074_Chip-Seq_ESCs_Mouse1.32864112
61CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.32773229
62IGF1R_20145208_ChIP-Seq_DFB_Human1.32542614
63FUS_26573619_Chip-Seq_HEK293_Human1.28212316
64* STAT3_23295773_ChIP-Seq_U87_Human1.27688093
65AR_25329375_ChIP-Seq_VCAP_Human1.26141364
66AHR_22903824_ChIP-Seq_MCF-7_Human1.24540130
67SOX2_21211035_ChIP-Seq_LN229_Gbm1.23872356
68TP53_20018659_ChIP-ChIP_R1E_Mouse1.23809306
69TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23405990
70* ARNT_22903824_ChIP-Seq_MCF-7_Human1.23233961
71AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23107482
72VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.22112640
73TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.19600066
74* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.19468134
75ZNF274_21170338_ChIP-Seq_K562_Hela1.18854849
76POU5F1_16153702_ChIP-ChIP_HESCs_Human1.18403095
77TP53_18474530_ChIP-ChIP_U2OS_Human1.17040368
78HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.16323323
79RING1B_27294783_Chip-Seq_ESCs_Mouse1.14221356
80* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.13103302
81ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.12840966
82UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.12821155
83ER_23166858_ChIP-Seq_MCF-7_Human1.12811604
84* AR_19668381_ChIP-Seq_PC3_Human1.12400666
85* TCF4_23295773_ChIP-Seq_U87_Human1.12107512
86MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.11181081
87P53_22127205_ChIP-Seq_FIBROBLAST_Human1.11093881
88NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.10500859
89EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.10439170
90SOX9_26525672_Chip-Seq_HEART_Mouse1.10315022
91NR3C1_21868756_ChIP-Seq_MCF10A_Human1.10057082
92NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.09756683
93NRF2_20460467_ChIP-Seq_MEFs_Mouse1.09756683
94CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.08436610
95TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08077952
96EP300_21415370_ChIP-Seq_HL-1_Mouse1.07196277
97ERG_21242973_ChIP-ChIP_JURKAT_Human1.07007662
98PRDM14_20953172_ChIP-Seq_ESCs_Human1.06806700
99* LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06717278
100BCAT_22108803_ChIP-Seq_LS180_Human1.05629188
101SMAD3_21741376_ChIP-Seq_HESCs_Human1.05489931
102SALL1_21062744_ChIP-ChIP_HESCs_Human1.05283989
103* RUNX2_22187159_ChIP-Seq_PCA_Human1.05183090
104KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04700386
105MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.04580193
106MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04499877
107TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.03582131
108RING1B_27294783_Chip-Seq_NPCs_Mouse1.01497851
109YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01299842
110NANOG_18555785_Chip-Seq_ESCs_Mouse1.00388792
111* POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.99773804
112* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99773804
113RNF2_27304074_Chip-Seq_NSC_Mouse0.99077234
114* TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96846676
115JUN_21703547_ChIP-Seq_K562_Human0.95921362
116* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.94942489
117SMAD4_21741376_ChIP-Seq_HESCs_Human0.94359197
118BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.93111119
119RXR_22108803_ChIP-Seq_LS180_Human0.91996397
120PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91345693

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.59481992
2MP0003880_abnormal_central_pattern5.05291126
3MP0003635_abnormal_synaptic_transmissio3.69407532
4MP0004270_analgesia3.46908513
5MP0009745_abnormal_behavioral_response3.15467675
6MP0002063_abnormal_learning/memory/cond2.91512707
7MP0002064_seizures2.91364692
8MP0009046_muscle_twitch2.74331338
9MP0002822_catalepsy2.71060023
10MP0001486_abnormal_startle_reflex2.61488244
11MP0002572_abnormal_emotion/affect_behav2.55021125
12MP0001968_abnormal_touch/_nociception2.54318725
13MP0002272_abnormal_nervous_system2.51203462
14MP0004084_abnormal_cardiac_muscle2.33209300
15MP0005423_abnormal_somatic_nervous2.31979535
16MP0001984_abnormal_olfaction2.28413898
17MP0002734_abnormal_mechanical_nocicepti2.25070577
18MP0001501_abnormal_sleep_pattern2.17504138
19MP0002736_abnormal_nociception_after1.97180937
20MP0005551_abnormal_eye_electrophysiolog1.94701903
21MP0000569_abnormal_digit_pigmentation1.89978265
22MP0001440_abnormal_grooming_behavior1.89486268
23MP0003646_muscle_fatigue1.89211646
24MP0004145_abnormal_muscle_electrophysio1.87697241
25MP0002735_abnormal_chemical_nociception1.81044232
26MP0002067_abnormal_sensory_capabilities1.79332945
27MP0009250_abnormal_appendicular_skeleto1.73583115
28MP0002837_dystrophic_cardiac_calcinosis1.70644134
29MP0000778_abnormal_nervous_system1.70258053
30MP0001529_abnormal_vocalization1.69473500
31MP0005409_darkened_coat_color1.66845685
32MP0001970_abnormal_pain_threshold1.66350825
33MP0001188_hyperpigmentation1.66205172
34MP0004924_abnormal_behavior1.64408101
35MP0005386_behavior/neurological_phenoty1.64408101
36MP0002184_abnormal_innervation1.64395383
37MP0000751_myopathy1.62041132
38MP0000049_abnormal_middle_ear1.56707920
39MP0002733_abnormal_thermal_nociception1.54351820
40MP0002909_abnormal_adrenal_gland1.54246145
41MP0005670_abnormal_white_adipose1.53731245
42MP0009780_abnormal_chondrocyte_physiolo1.51316241
43MP0008569_lethality_at_weaning1.51197570
44MP0003879_abnormal_hair_cell1.51174267
45MP0006276_abnormal_autonomic_nervous1.49979017
46MP0002557_abnormal_social/conspecific_i1.46985008
47MP0002102_abnormal_ear_morphology1.46882132
48MP0002106_abnormal_muscle_physiology1.44468762
49MP0005369_muscle_phenotype1.44385416
50MP0003937_abnormal_limbs/digits/tail_de1.39703480
51MP0004134_abnormal_chest_morphology1.39131795
52MP0002882_abnormal_neuron_morphology1.39032697
53MP0001905_abnormal_dopamine_level1.38452658
54MP0006292_abnormal_olfactory_placode1.34395352
55MP0004087_abnormal_muscle_fiber1.33311965
56MP0005646_abnormal_pituitary_gland1.33031731
57MP0010386_abnormal_urinary_bladder1.32926184
58MP0002127_abnormal_cardiovascular_syste1.32823143
59MP0000534_abnormal_ureter_morphology1.32570613
60MP0005187_abnormal_penis_morphology1.32548991
61MP0004811_abnormal_neuron_physiology1.32460087
62MP0008775_abnormal_heart_ventricle1.30907948
63MP0003942_abnormal_urinary_system1.28931849
64MP0003329_amyloid_beta_deposits1.26783069
65MP0002066_abnormal_motor_capabilities/c1.24375214
66MP0000750_abnormal_muscle_regeneration1.23429756
67MP0000955_abnormal_spinal_cord1.22112774
68MP0002638_abnormal_pupillary_reflex1.19702247
69MP0002972_abnormal_cardiac_muscle1.17304678
70MP0003633_abnormal_nervous_system1.17194355
71MP0002090_abnormal_vision1.15447330
72MP0008438_abnormal_cutaneous_collagen1.14971167
73MP0001544_abnormal_cardiovascular_syste1.13770804
74MP0005385_cardiovascular_system_phenoty1.13770804
75MP0002938_white_spotting1.13488887
76MP0001502_abnormal_circadian_rhythm1.13026086
77MP0004885_abnormal_endolymph1.12600873
78MP0005623_abnormal_meninges_morphology1.12173705
79MP0004272_abnormal_basement_membrane1.11442325
80MP0002160_abnormal_reproductive_system1.10929523
81MP0002229_neurodegeneration1.10760278
82MP0000920_abnormal_myelination1.07979001
83MP0004215_abnormal_myocardial_fiber1.07958329
84MP0004484_altered_response_of1.07926321
85MP0006138_congestive_heart_failure1.06772692
86MP0005645_abnormal_hypothalamus_physiol1.06762384
87MP0003567_abnormal_fetal_cardiomyocyte1.06535818
88MP0000759_abnormal_skeletal_muscle1.04602072
89MP0004085_abnormal_heartbeat1.02087475
90MP0010368_abnormal_lymphatic_system1.00942675
91MP0004510_myositis0.99510471
92MP0004858_abnormal_nervous_system0.97644191
93MP0003787_abnormal_imprinting0.97619088
94MP0003283_abnormal_digestive_organ0.95904338
95MP0000428_abnormal_craniofacial_morphol0.95257210
96MP0006072_abnormal_retinal_apoptosis0.94726191
97MP0004142_abnormal_muscle_tone0.94642179
98MP0004742_abnormal_vestibular_system0.94285419
99MP0003631_nervous_system_phenotype0.93567797
100MP0002752_abnormal_somatic_nervous0.92865321
101MP0003755_abnormal_palate_morphology0.92692412
102MP0005275_abnormal_skin_tensile0.92036477
103MP0000026_abnormal_inner_ear0.91927677
104MP0002152_abnormal_brain_morphology0.91392987
105MP0003634_abnormal_glial_cell0.91259139
106MP0004233_abnormal_muscle_weight0.89409198
107MP0001963_abnormal_hearing_physiology0.88913343
108MP0005253_abnormal_eye_physiology0.88412826
109MP0004036_abnormal_muscle_relaxation0.87613540
110MP0003122_maternal_imprinting0.85894808
111MP0005620_abnormal_muscle_contractility0.84970738
112MP0003690_abnormal_glial_cell0.84678219
113MP0010030_abnormal_orbit_morphology0.84104641
114MP0001177_atelectasis0.83562477
115MP0002234_abnormal_pharynx_morphology0.83070911
116MP0002116_abnormal_craniofacial_bone0.82777238
117MP0000462_abnormal_digestive_system0.82686138
118MP0010630_abnormal_cardiac_muscle0.81865197
119MP0008874_decreased_physiological_sensi0.81040030
120MP0000013_abnormal_adipose_tissue0.80935492
121MP0009384_cardiac_valve_regurgitation0.80869989
122MP0001879_abnormal_lymphatic_vessel0.80506720
123MP0000733_abnormal_muscle_development0.80155835
124MP0003137_abnormal_impulse_conducting0.78497832
125MP0000749_muscle_degeneration0.76085061
126MP0005171_absent_coat_pigmentation0.75876498
127MP0005394_taste/olfaction_phenotype0.73709242
128MP0005499_abnormal_olfactory_system0.73709242
129MP0002069_abnormal_eating/drinking_beha0.72297660
130MP0005195_abnormal_posterior_eye0.71524408
131MP0000747_muscle_weakness0.70992628
132MP0001299_abnormal_eye_distance/0.69180678
133MP0005535_abnormal_body_temperature0.68874293
134MP0002108_abnormal_muscle_morphology0.68602278
135MP0003045_fibrosis0.68516790
136MP0005503_abnormal_tendon_morphology0.66666931
137MP0000631_abnormal_neuroendocrine_gland0.63832475
138MP0004130_abnormal_muscle_cell0.62887399
139MP0000604_amyloidosis0.61838111
140MP0001485_abnormal_pinna_reflex0.60335272
141MP0005595_abnormal_vascular_smooth0.59952973

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.98894379
2Focal seizures (HP:0007359)5.25764834
3Myokymia (HP:0002411)5.05341765
4Febrile seizures (HP:0002373)4.54411460
5Visual hallucinations (HP:0002367)4.47659974
6Epileptic encephalopathy (HP:0200134)4.42477355
7Atonic seizures (HP:0010819)4.33522406
8Absence seizures (HP:0002121)3.95079678
9Dialeptic seizures (HP:0011146)3.66536292
10Progressive cerebellar ataxia (HP:0002073)3.50447579
11Generalized tonic-clonic seizures (HP:0002069)3.46835047
12Congenital stationary night blindness (HP:0007642)3.35621329
13Short 4th metacarpal (HP:0010044)3.35376485
14Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.35376485
15Broad-based gait (HP:0002136)3.34929279
16Abnormality of the phalanges of the 2nd finger (HP:0009541)3.29918801
17Type 1 muscle fiber predominance (HP:0003803)3.28558742
18Atrial fibrillation (HP:0005110)3.27566024
19Bundle branch block (HP:0011710)3.27529372
20Hyperventilation (HP:0002883)3.27155621
21Amblyopia (HP:0000646)3.12885500
22Supranuclear gaze palsy (HP:0000605)3.08643257
23Action tremor (HP:0002345)3.06685054
24Muscle fiber inclusion bodies (HP:0100299)2.94057051
25Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.87477433
26Central scotoma (HP:0000603)2.87415964
27Cerebral inclusion bodies (HP:0100314)2.85097855
28Gaze-evoked nystagmus (HP:0000640)2.83742029
29Nemaline bodies (HP:0003798)2.80676511
30Supraventricular tachycardia (HP:0004755)2.80036973
31Neurofibrillary tangles (HP:0002185)2.78878949
32Truncal ataxia (HP:0002078)2.75675014
33Hyporeflexia of lower limbs (HP:0002600)2.74609207
34Dysdiadochokinesis (HP:0002075)2.72776043
35Supraventricular arrhythmia (HP:0005115)2.72500857
36Absent speech (HP:0001344)2.70710327
37Abnormality of macular pigmentation (HP:0008002)2.69238858
38Dysmetria (HP:0001310)2.68558289
39Anxiety (HP:0000739)2.66489682
40Abnormality of the 4th metacarpal (HP:0010012)2.61721735
41Drooling (HP:0002307)2.60922486
42Excessive salivation (HP:0003781)2.60922486
43Depression (HP:0000716)2.58473191
44Abnormality of the middle phalanges of the toes (HP:0010183)2.55459355
45Distal arthrogryposis (HP:0005684)2.49706609
46Mesomelia (HP:0003027)2.49462471
47Poor eye contact (HP:0000817)2.47692465
48Absent phalangeal crease (HP:0006109)2.46359446
49Urinary bladder sphincter dysfunction (HP:0002839)2.42809250
50Short hallux (HP:0010109)2.41113461
51Difficulty running (HP:0009046)2.39472941
52Muscle hypertrophy of the lower extremities (HP:0008968)2.38125871
53Ventricular fibrillation (HP:0001663)2.36373254
54Widely spaced teeth (HP:0000687)2.34714178
55Lower limb amyotrophy (HP:0007210)2.34182128
56Cutaneous finger syndactyly (HP:0010554)2.33951196
57Genetic anticipation (HP:0003743)2.33712882
58Abnormality of the proximal phalanges of the hand (HP:0009834)2.33507077
59Progressive inability to walk (HP:0002505)2.33437966
60Hip contracture (HP:0003273)2.33270307
61Scanning speech (HP:0002168)2.32791371
62Hemiparesis (HP:0001269)2.32503244
63Symphalangism affecting the phalanges of the hand (HP:0009773)2.26966552
64Abnormal social behavior (HP:0012433)2.25090008
65Impaired social interactions (HP:0000735)2.25090008
66Prolonged QT interval (HP:0001657)2.23464807
67Gait imbalance (HP:0002141)2.23434851
68Postural instability (HP:0002172)2.23227013
69Aplasia/Hypoplasia of the hallux (HP:0008362)2.23135293
70Stereotypic behavior (HP:0000733)2.22441327
71Abnormality of the 2nd finger (HP:0004100)2.22427175
72Impaired vibration sensation in the lower limbs (HP:0002166)2.22364724
73Ventricular arrhythmia (HP:0004308)2.20235573
74Myotonia (HP:0002486)2.19100004
75Muscle fiber splitting (HP:0003555)2.18225312
76Conjunctival hamartoma (HP:0100780)2.16596000
77Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.16363629
78Dyschromatopsia (HP:0007641)2.15864414
79Diplopia (HP:0000651)2.15456157
80Abnormality of binocular vision (HP:0011514)2.15456157
81Coronal craniosynostosis (HP:0004440)2.14729176
82Ventricular tachycardia (HP:0004756)2.11802269
83Exotropia (HP:0000577)2.11070115
84Termporal pattern (HP:0011008)2.07663961
85Insidious onset (HP:0003587)2.07663961
86Limited hip movement (HP:0008800)2.06079421
87Abnormality of the phalanges of the 5th finger (HP:0004213)2.05897386
88Calf muscle hypertrophy (HP:0008981)2.05529672
89Lipoatrophy (HP:0100578)2.05383501
90Distal lower limb amyotrophy (HP:0008944)2.05068120
91Morphological abnormality of the middle ear (HP:0008609)2.04752079
92Keratoconus (HP:0000563)2.03756621
93Increased corneal curvature (HP:0100692)2.03756621
94Exercise-induced myalgia (HP:0003738)2.03279641
95Round ear (HP:0100830)2.02290822
96Ankle clonus (HP:0011448)2.02251745
97Congenital primary aphakia (HP:0007707)2.01370212
98Epileptiform EEG discharges (HP:0011182)1.99782191
99Papilledema (HP:0001085)1.99118000
100Hamartoma of the eye (HP:0010568)1.98787902
101Retinal dysplasia (HP:0007973)1.98667418
102Intention tremor (HP:0002080)1.98171552
103Inability to walk (HP:0002540)1.98053571
104EMG: myopathic abnormalities (HP:0003458)1.97414838
105Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.96965562
106Short 1st metacarpal (HP:0010034)1.96965562
107Pancreatic fibrosis (HP:0100732)1.96699076
108Abnormal finger flexion creases (HP:0006143)1.96668073
109Sudden death (HP:0001699)1.96630182
110Asymmetric septal hypertrophy (HP:0001670)1.96472793
111Scotoma (HP:0000575)1.95570773
112Abnormal EKG (HP:0003115)1.94533330
113Subaortic stenosis (HP:0001682)1.94486714
114Abnormality of the left ventricular outflow tract (HP:0011103)1.94486714
115Anomalous pulmonary venous return (HP:0010772)1.94229714
116Cutaneous syndactyly (HP:0012725)1.93219892
117Mutism (HP:0002300)1.92218289
118Syncope (HP:0001279)1.92032053
119Impaired smooth pursuit (HP:0007772)1.92011189
120Abnormal eating behavior (HP:0100738)1.89844990
121Abnormality of the calf musculature (HP:0001430)1.89389209
122Aplasia involving bones of the extremities (HP:0009825)1.88666911
123Aplasia involving bones of the upper limbs (HP:0009823)1.88666911
124Abnormality of the ischium (HP:0003174)1.87921267
125Hydroureter (HP:0000072)1.87683126
126Abnormality of salivation (HP:0100755)1.87544366
127Medial flaring of the eyebrow (HP:0010747)1.86413797
128Rapidly progressive (HP:0003678)1.85693003
129Degeneration of the lateral corticospinal tracts (HP:0002314)1.84826341
130Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.84826341
131Spastic gait (HP:0002064)1.84467421
132Heart block (HP:0012722)1.84187503
133Torticollis (HP:0000473)1.84165234
134Pancreatic cysts (HP:0001737)1.83985214
135Fetal akinesia sequence (HP:0001989)1.83958288
136Choroideremia (HP:0001139)1.83072581
137EEG with generalized epileptiform discharges (HP:0011198)1.82385912
138Hypoventilation (HP:0002791)1.81456698
139Generalized myoclonic seizures (HP:0002123)1.81254849
140Synostosis of carpal bones (HP:0005048)1.80545172
141Decreased central vision (HP:0007663)1.80474463
142Hyperthyroidism (HP:0000836)1.80473215
143Blue irides (HP:0000635)1.80241361
144Bony spicule pigmentary retinopathy (HP:0007737)1.79793983
145Pheochromocytoma (HP:0002666)1.78941586
146Congenital sensorineural hearing impairment (HP:0008527)1.78790529
147Genital tract atresia (HP:0001827)1.78638197
148Hypoplastic ischia (HP:0003175)1.78049348
149Nephrogenic diabetes insipidus (HP:0009806)1.77394954
150Dysmetric saccades (HP:0000641)1.77075742
151Left ventricular hypertrophy (HP:0001712)1.76566338
152Vaginal atresia (HP:0000148)1.76345386
153Arterial tortuosity (HP:0005116)1.75965133
154Protruding tongue (HP:0010808)1.75898652
155Exercise-induced muscle cramps (HP:0003710)1.74942841
156Abnormality of the corticospinal tract (HP:0002492)1.74322868
157Nephronophthisis (HP:0000090)1.73688615
158Specific learning disability (HP:0001328)1.71415822
159Buphthalmos (HP:0000557)1.71316546
160Periauricular skin pits (HP:0100277)1.70998194
161Preauricular pit (HP:0004467)1.70998194
162Palpitations (HP:0001962)1.70431580
163Abnormality of the pulmonary veins (HP:0011718)1.69722160
164True hermaphroditism (HP:0010459)1.68430495
165Primary atrial arrhythmia (HP:0001692)1.68105982
166Incomplete penetrance (HP:0003829)1.67915959
167Aplasia of the phalanges of the hand (HP:0009802)1.67403857
168Fibular aplasia (HP:0002990)1.67111034
169Aortic aneurysm (HP:0004942)1.66583603
170Bone cyst (HP:0012062)1.65167577
171Abnormality of the 1st metacarpal (HP:0010009)1.63663642
172Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.63513434
173Hypoplasia of the ulna (HP:0003022)1.61400310
174Deformed tarsal bones (HP:0008119)1.61380910
175Aplasia/Hypoplasia of the tibia (HP:0005772)1.59507179
176Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.59470939
177Neck muscle weakness (HP:0000467)1.59417735
178Right ventricular cardiomyopathy (HP:0011663)1.58456714
179Short tibia (HP:0005736)1.57388735

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA45.04633879
2NTRK34.14808199
3OBSCN4.12370629
4RIPK43.44584596
5MAP3K42.79233147
6MAP3K92.51338087
7MAP2K72.36285018
8FRK2.34233959
9PNCK2.26873911
10TNIK2.25417386
11MYLK2.07936106
12MINK11.97010319
13WNK31.94031918
14DAPK21.94025511
15PAK61.92787485
16MARK11.90411403
17BRSK21.89036471
18PLK21.88503997
19TAF11.87360410
20NEK91.85957251
21CASK1.84008129
22NTRK11.82120419
23MAP2K41.68426027
24MAP3K121.58467780
25MAP3K131.57804472
26BMPR21.54003504
27TTN1.53074198
28FES1.48432508
29NTRK21.48360372
30CDK51.45126063
31CAMK1G1.41765613
32SIK21.39359706
33PTK2B1.36617656
34GRK51.34079175
35KSR21.28985600
36KSR11.27555822
37CAMKK11.25529209
38PIK3CA1.24465948
39EPHB21.24165039
40LATS11.23863229
41CAMK2A1.20031202
42GRK11.19147434
43CAMKK21.15829497
44PHKG21.14110287
45PHKG11.14110287
46PRKCG1.12764499
47MAPK131.12702513
48MAP4K21.12234099
49NUAK11.11602127
50FGR1.10442781
51DAPK11.10419410
52PRKD31.10004110
53PRPF4B1.06420832
54CAMK2B1.05680378
55STK381.02157176
56STK38L1.00740876
57ARAF0.94353674
58GRK70.91684969
59WEE10.91650316
60STK110.91464614
61PAK30.90871791
62OXSR10.90468592
63SGK10.89952143
64CAMK10.89872753
65NME10.89833910
66CAMK2D0.89445377
67PRKCE0.88397590
68SGK4940.86267071
69SGK2230.86267071
70PRKAA10.85547446
71WNK10.84802602
72BMPR1B0.82382930
73DYRK20.79843613
74DMPK0.78975332
75CDK190.78138458
76FGFR20.74896156
77STK390.73805842
78CAMK40.73023620
79EPHA30.71572512
80PRKCH0.71320179
81MAP3K20.68408748
82SGK20.67712272
83WNK40.67680809
84MAP3K70.67423237
85CSNK1G10.66489110
86MARK20.66480929
87FER0.65958740
88CDK180.65703829
89PRKG10.65347089
90TYRO30.64904510
91CDK140.64419822
92MAPKAPK50.63992655
93INSRR0.63839638
94CDK150.63230797
95UHMK10.63228143
96NLK0.62998268
97ROCK20.62728908
98DDR20.61981387
99PRKD20.61633122
100DYRK1A0.61282710
101PRKACA0.61047715
102NEK60.58146764
103FYN0.57478953
104RPS6KA60.57095399
105PRKAA20.56644243
106RET0.55624367
107CSNK1A1L0.55137755
108ADRBK10.54941125
109PKN10.54685395
110BRSK10.54623268
111MUSK0.53457793
112LATS20.53387134
113CAMK2G0.52764982
114PDGFRA0.52752011
115BCR0.52683861
116PDGFRB0.52263438
117CDK11A0.52176798
118TIE10.51482603
119RPS6KL10.50977349
120RPS6KC10.50977349
121AKT30.50930554
122RAF10.50119801
123MAPK120.49652648
124PRKCZ0.49484068
125CSNK1G20.49445040
126SGK30.49091483
127MAPK100.48796402
128RPS6KA30.48169646
129PDK10.48082454
130TRPM70.47812696
131PDPK10.47724459
132MKNK20.47573490
133CAMK1D0.47552955
134PRKD10.47524530
135ROCK10.46459123
136PIK3CG0.45768448
137GSK3A0.45652545
138ADRBK20.44399618
139MAPK40.44376499
140MAPK70.43836741
141PINK10.43810472
142MOS0.43046874
143TAOK10.42380786

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.19848591
2Olfactory transduction_Homo sapiens_hsa047402.77431881
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.59616086
4Circadian entrainment_Homo sapiens_hsa047132.56962654
5Synaptic vesicle cycle_Homo sapiens_hsa047212.48799181
6Glutamatergic synapse_Homo sapiens_hsa047242.46409500
7GABAergic synapse_Homo sapiens_hsa047272.43328405
8Morphine addiction_Homo sapiens_hsa050322.41869382
9Long-term potentiation_Homo sapiens_hsa047202.37384669
10Phototransduction_Homo sapiens_hsa047442.32271195
11Amphetamine addiction_Homo sapiens_hsa050312.23397816
12Salivary secretion_Homo sapiens_hsa049702.17154295
13Dopaminergic synapse_Homo sapiens_hsa047282.02408346
14Renin secretion_Homo sapiens_hsa049241.87399971
15Cholinergic synapse_Homo sapiens_hsa047251.86323804
16Insulin secretion_Homo sapiens_hsa049111.78919527
17Serotonergic synapse_Homo sapiens_hsa047261.78239614
18Taste transduction_Homo sapiens_hsa047421.76038907
19Oxytocin signaling pathway_Homo sapiens_hsa049211.74966194
20Gastric acid secretion_Homo sapiens_hsa049711.74721989
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.74379739
22Calcium signaling pathway_Homo sapiens_hsa040201.73714954
23Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.66269916
24Long-term depression_Homo sapiens_hsa047301.60389585
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.55972001
26Hedgehog signaling pathway_Homo sapiens_hsa043401.52095532
27Cocaine addiction_Homo sapiens_hsa050301.47208202
28GnRH signaling pathway_Homo sapiens_hsa049121.44090184
29Collecting duct acid secretion_Homo sapiens_hsa049661.40529758
30Basal cell carcinoma_Homo sapiens_hsa052171.34861677
31cAMP signaling pathway_Homo sapiens_hsa040241.29885977
32Gap junction_Homo sapiens_hsa045401.28109121
33Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.26412596
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.25683281
35Axon guidance_Homo sapiens_hsa043601.24626361
36Dilated cardiomyopathy_Homo sapiens_hsa054141.23797394
37Cardiac muscle contraction_Homo sapiens_hsa042601.22051649
38cGMP-PKG signaling pathway_Homo sapiens_hsa040221.20716464
39Melanoma_Homo sapiens_hsa052181.19266468
40Vascular smooth muscle contraction_Homo sapiens_hsa042701.16693962
41Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.10115502
42Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.09169133
43Phosphatidylinositol signaling system_Homo sapiens_hsa040701.08534889
44Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06283010
45Type II diabetes mellitus_Homo sapiens_hsa049301.06181535
46Propanoate metabolism_Homo sapiens_hsa006401.01996452
47Glioma_Homo sapiens_hsa052141.01579079
48Maturity onset diabetes of the young_Homo sapiens_hsa049501.01505703
49Estrogen signaling pathway_Homo sapiens_hsa049151.01336836
50Melanogenesis_Homo sapiens_hsa049160.98749256
51Vibrio cholerae infection_Homo sapiens_hsa051100.98639100
52Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.96038038
53Pancreatic secretion_Homo sapiens_hsa049720.93971168
54Hippo signaling pathway_Homo sapiens_hsa043900.91297741
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.90112721
56Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.89314826
57Protein digestion and absorption_Homo sapiens_hsa049740.88649094
58Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.88551782
59Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.86937243
60Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.86507362
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.85111768
62Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.84478641
63ErbB signaling pathway_Homo sapiens_hsa040120.84098202
64TGF-beta signaling pathway_Homo sapiens_hsa043500.83171666
65Alzheimers disease_Homo sapiens_hsa050100.82454739
66Butanoate metabolism_Homo sapiens_hsa006500.81678295
67Choline metabolism in cancer_Homo sapiens_hsa052310.79917058
68Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79232163
69Sulfur metabolism_Homo sapiens_hsa009200.74851112
70MAPK signaling pathway_Homo sapiens_hsa040100.73202153
71Thyroid hormone synthesis_Homo sapiens_hsa049180.72145258
72Dorso-ventral axis formation_Homo sapiens_hsa043200.69998132
73VEGF signaling pathway_Homo sapiens_hsa043700.69377911
74Ras signaling pathway_Homo sapiens_hsa040140.67698925
75African trypanosomiasis_Homo sapiens_hsa051430.66643628
76Tight junction_Homo sapiens_hsa045300.66193775
77Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63171576
78Oxidative phosphorylation_Homo sapiens_hsa001900.62763765
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62641716
80Rap1 signaling pathway_Homo sapiens_hsa040150.62511791
81AMPK signaling pathway_Homo sapiens_hsa041520.61993263
82Nitrogen metabolism_Homo sapiens_hsa009100.60466045
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.60060437
84Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.59640847
85Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.58725974
86Tryptophan metabolism_Homo sapiens_hsa003800.56191033
87Ovarian steroidogenesis_Homo sapiens_hsa049130.55969097
88Circadian rhythm_Homo sapiens_hsa047100.55193627
89Wnt signaling pathway_Homo sapiens_hsa043100.53489786
90Rheumatoid arthritis_Homo sapiens_hsa053230.53129899
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52678980
92Glucagon signaling pathway_Homo sapiens_hsa049220.52380342
93Glycerolipid metabolism_Homo sapiens_hsa005610.52239977
94Selenocompound metabolism_Homo sapiens_hsa004500.51909758
95PPAR signaling pathway_Homo sapiens_hsa033200.50278734
96Inositol phosphate metabolism_Homo sapiens_hsa005620.49220130
97Oocyte meiosis_Homo sapiens_hsa041140.49163233
98Adherens junction_Homo sapiens_hsa045200.48915328
99Insulin resistance_Homo sapiens_hsa049310.48085019
100Renal cell carcinoma_Homo sapiens_hsa052110.47959812
101Bile secretion_Homo sapiens_hsa049760.47479350
102Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47196961
103mTOR signaling pathway_Homo sapiens_hsa041500.47166714
104Steroid hormone biosynthesis_Homo sapiens_hsa001400.47137820
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46827776
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46502080
107Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.46210454
108Chemokine signaling pathway_Homo sapiens_hsa040620.46000527
109Regulation of autophagy_Homo sapiens_hsa041400.45644312
110Thyroid hormone signaling pathway_Homo sapiens_hsa049190.45479316
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45044773
112Endocytosis_Homo sapiens_hsa041440.44693690
113Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43868618
114PI3K-Akt signaling pathway_Homo sapiens_hsa041510.42813573
115Platelet activation_Homo sapiens_hsa046110.42289901
116Neurotrophin signaling pathway_Homo sapiens_hsa047220.42098531
117Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.41439833
118beta-Alanine metabolism_Homo sapiens_hsa004100.41086244
119Parkinsons disease_Homo sapiens_hsa050120.39117150
120Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.39056672
121Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.38401170
122Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36824020
123Alcoholism_Homo sapiens_hsa050340.35090748
124Regulation of actin cytoskeleton_Homo sapiens_hsa048100.34016584
125Focal adhesion_Homo sapiens_hsa045100.32357010
126Amoebiasis_Homo sapiens_hsa051460.30489281
127Insulin signaling pathway_Homo sapiens_hsa049100.29369161
128Non-small cell lung cancer_Homo sapiens_hsa052230.28678708
129Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.26676692
130ECM-receptor interaction_Homo sapiens_hsa045120.26593834
131AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.26215770

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