RNF151

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1spermatid development (GO:0007286)9.87852942
2epithelial cilium movement (GO:0003351)9.77886011
3axonemal dynein complex assembly (GO:0070286)9.59865485
4reproduction (GO:0000003)9.44379599
5motile cilium assembly (GO:0044458)9.28308536
6response to pheromone (GO:0019236)9.07830803
7regulation of cilium movement (GO:0003352)8.50056127
8cilium or flagellum-dependent cell motility (GO:0001539)8.39556277
9cilium movement (GO:0003341)7.89807124
10rRNA methylation (GO:0031167)7.33926617
11sperm capacitation (GO:0048240)7.32953655
12single fertilization (GO:0007338)7.31269354
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.28519431
14negative regulation of inclusion body assembly (GO:0090084)7.23893941
15synaptonemal complex organization (GO:0070193)7.20340516
16synaptonemal complex assembly (GO:0007130)7.14298256
17male meiosis (GO:0007140)6.97652431
18* spermatogenesis (GO:0007283)6.72097263
19* male gamete generation (GO:0048232)6.69647184
20piRNA metabolic process (GO:0034587)6.68461997
21phosphatidylethanolamine biosynthetic process (GO:0006646)6.65593865
22organic cation transport (GO:0015695)6.64158903
23microtubule depolymerization (GO:0007019)6.61887145
24protein targeting to Golgi (GO:0000042)6.36439838
25fertilization (GO:0009566)6.21486101
26rRNA modification (GO:0000154)6.19248299
27* gamete generation (GO:0007276)6.15363143
28phosphatidylethanolamine metabolic process (GO:0046337)6.12966246
29establishment of protein localization to Golgi (GO:0072600)6.10628368
30regulation of inclusion body assembly (GO:0090083)6.05575289
31retrograde transport, vesicle recycling within Golgi (GO:0000301)5.91265939
32cellular ketone body metabolic process (GO:0046950)5.86770335
33calcium ion-dependent exocytosis (GO:0017156)5.62517582
34chromosome condensation (GO:0030261)5.55584532
35spermatid nucleus differentiation (GO:0007289)5.54799152
36germ cell development (GO:0007281)5.48190228
37cellular process involved in reproduction in multicellular organism (GO:0022412)5.42934680
38DNA packaging (GO:0006323)5.25838773
39ketone body metabolic process (GO:1902224)5.17216679
40antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.17166780
41cell recognition (GO:0008037)5.09917524
42glycerol ether metabolic process (GO:0006662)5.07109474
43centriole replication (GO:0007099)5.06521042
44ventricular system development (GO:0021591)5.04053411
45positive regulation of Rab GTPase activity (GO:0032851)5.03745081
46regulation of Rab GTPase activity (GO:0032313)5.03745081
47regulation of microtubule-based movement (GO:0060632)4.98975641
48microtubule severing (GO:0051013)4.93580262
49* multicellular organismal reproductive process (GO:0048609)4.83906825
50chromosome organization involved in meiosis (GO:0070192)4.83633454
51ether metabolic process (GO:0018904)4.68617754
52male meiosis I (GO:0007141)4.64107583
53centriole assembly (GO:0098534)4.63205265
54protein localization to Golgi apparatus (GO:0034067)4.61052993
55sexual reproduction (GO:0019953)4.60589549
56seminiferous tubule development (GO:0072520)4.56037408
57single strand break repair (GO:0000012)4.39753551
58regulation of transcription involved in cell fate commitment (GO:0060850)4.36428934
59DNA methylation involved in gamete generation (GO:0043046)4.33745375
60chaperone-mediated protein complex assembly (GO:0051131)4.23310182
61left/right pattern formation (GO:0060972)4.18890602
62regulation of centriole replication (GO:0046599)4.17853464
63meiotic nuclear division (GO:0007126)4.17831203
64coenzyme catabolic process (GO:0009109)3.95592563
65multicellular organismal development (GO:0007275)3.95048853
66sequestering of actin monomers (GO:0042989)3.88579741
67negative regulation of Rho protein signal transduction (GO:0035024)3.81373317
68meiosis I (GO:0007127)3.71512021
69protein K11-linked deubiquitination (GO:0035871)3.61760219
70protein polyglutamylation (GO:0018095)3.58672852
71multicellular organismal movement (GO:0050879)3.58436783
72musculoskeletal movement (GO:0050881)3.58436783
73genitalia morphogenesis (GO:0035112)3.53814367
74cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.45521553
75negative regulation of gene expression, epigenetic (GO:0045814)3.43205174
76response to acidic pH (GO:0010447)3.39548634
77monoubiquitinated protein deubiquitination (GO:0035520)3.38694444
78microtubule polymerization or depolymerization (GO:0031109)3.38605210
79peptidyl-threonine dephosphorylation (GO:0035970)3.38030430
80regulation of spindle checkpoint (GO:0090231)3.37781373
81glomerular visceral epithelial cell development (GO:0072015)3.32391688
82protein refolding (GO:0042026)3.30120101
83meiotic cell cycle (GO:0051321)3.23030746
84membrane protein intracellular domain proteolysis (GO:0031293)3.22941096
85cerebral cortex neuron differentiation (GO:0021895)3.22929920
86glomerular epithelial cell development (GO:0072310)3.21717931
87regulation of interleukin-13 production (GO:0032656)3.20962474
88cellular response to pH (GO:0071467)3.19317360
89glycolytic process (GO:0006096)3.18403583
90positive regulation of macrophage activation (GO:0043032)3.17731848
91cranial nerve morphogenesis (GO:0021602)3.17586108
92protein depolymerization (GO:0051261)3.17532506
93nucleus organization (GO:0006997)3.17334658
94DNA conformation change (GO:0071103)3.15942504
95regulation of T-helper 2 cell differentiation (GO:0045628)3.14094946
96histone H3-K9 demethylation (GO:0033169)3.13020232
97homeostasis of number of cells within a tissue (GO:0048873)3.10347921
98interferon-gamma secretion (GO:0072643)3.05686704
99carnitine transport (GO:0015879)3.05423690
100amino-acid betaine transport (GO:0015838)3.05423690
101mitotic sister chromatid cohesion (GO:0007064)3.05394122
102protein localization to cilium (GO:0061512)3.01493523
103microtubule nucleation (GO:0007020)3.00750326
104mesenchymal cell differentiation involved in kidney development (GO:0072161)2.99626766
105mesenchymal cell differentiation involved in renal system development (GO:2001012)2.99626766
106nucleoside diphosphate phosphorylation (GO:0006165)2.98012178
107polyol catabolic process (GO:0046174)2.93997767
108chromatin silencing (GO:0006342)2.89393450
109carnitine transmembrane transport (GO:1902603)2.88356133
110polyamine biosynthetic process (GO:0006596)2.87832506
111NAD biosynthetic process (GO:0009435)2.86061545
112cell differentiation involved in metanephros development (GO:0072202)2.84932689
113RNA localization (GO:0006403)2.84128423
114regulation of somitogenesis (GO:0014807)2.83272701
115alditol metabolic process (GO:0019400)2.82413317
116meiotic cell cycle process (GO:1903046)2.80360042
117GTP biosynthetic process (GO:0006183)2.78550079
118synapsis (GO:0007129)2.77605038
119negative regulation of histone methylation (GO:0031061)2.75925879
120regulation of ARF GTPase activity (GO:0032312)2.73092276
121cilium organization (GO:0044782)2.71691607
122mitotic G1 DNA damage checkpoint (GO:0031571)2.70940615
123microtubule-based movement (GO:0007018)2.66464585
124RNA destabilization (GO:0050779)2.65942913
125regulation of phosphoprotein phosphatase activity (GO:0043666)2.65417830
126cellular component assembly involved in morphogenesis (GO:0010927)2.62952333
127regulation of cilium assembly (GO:1902017)2.61227508
128cilium assembly (GO:0042384)2.60097006
129cilium morphogenesis (GO:0060271)2.59018809
130intraciliary transport (GO:0042073)2.55560666
131lactate metabolic process (GO:0006089)2.55516744
132axoneme assembly (GO:0035082)2.52572509
133negative regulation of organelle assembly (GO:1902116)2.50841275
134UTP biosynthetic process (GO:0006228)2.50119952
135nucleosome disassembly (GO:0006337)2.44691486
136protein-DNA complex disassembly (GO:0032986)2.44691486
137peptidyl-glutamic acid modification (GO:0018200)2.44124887
138sperm motility (GO:0030317)14.1438321
139cell wall macromolecule metabolic process (GO:0044036)13.7419549
140cell wall macromolecule catabolic process (GO:0016998)13.7419549
141fusion of sperm to egg plasma membrane (GO:0007342)13.1789417
142acrosome reaction (GO:0007340)12.3073324
143acrosome assembly (GO:0001675)12.0546016
144sperm-egg recognition (GO:0035036)11.7835789
145multicellular organism reproduction (GO:0032504)10.8260532
146binding of sperm to zona pellucida (GO:0007339)10.7596674
147cell-cell recognition (GO:0009988)10.5539818
148plasma membrane fusion (GO:0045026)10.0324049

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse9.54627777
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.81817776
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.27238269
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.11579057
5EZH2_22144423_ChIP-Seq_EOC_Human3.93650616
6MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human3.81568853
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.15288652
8BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.91374930
9PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.90105768
10STAT6_21828071_ChIP-Seq_BEAS2B_Human2.84354141
11VDR_22108803_ChIP-Seq_LS180_Human2.46575177
12CREM_20920259_ChIP-Seq_GC1-SPG_Mouse2.32928944
13GATA1_26923725_Chip-Seq_HPCs_Mouse2.23036341
14CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.18398219
15VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.09977504
16ERA_21632823_ChIP-Seq_H3396_Human2.09900459
17ZNF274_21170338_ChIP-Seq_K562_Hela2.06504583
18EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human2.04926302
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.02524272
20CTCF_27219007_Chip-Seq_Bcells_Human2.02383376
21RAC3_21632823_ChIP-Seq_H3396_Human1.97229278
22EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.95073174
23NANOG_20526341_ChIP-Seq_ESCs_Human1.93343692
24BCL6_27268052_Chip-Seq_Bcells_Human1.92172365
25KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.89686022
26E2F1_20622854_ChIP-Seq_HELA_Human1.88458947
27P68_20966046_ChIP-Seq_HELA_Human1.87724173
28* RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.87466744
29DROSHA_22980978_ChIP-Seq_HELA_Human1.87138064
30CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81875824
31SMC4_20622854_ChIP-Seq_HELA_Human1.80357728
32LXR_22292898_ChIP-Seq_THP-1_Human1.78312824
33GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.78261254
34FLI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.78099670
35ELK4_26923725_Chip-Seq_MESODERM_Mouse1.75664009
36PHF8_20622854_ChIP-Seq_HELA_Human1.74863908
37FUS_26573619_Chip-Seq_HEK293_Human1.74002712
38STAT1_17558387_ChIP-Seq_HELA_Human1.73677999
39ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.72799837
40TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.72719227
41TAF2_19829295_ChIP-Seq_ESCs_Human1.70710074
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.70290601
43TDRD3_21172665_ChIP-Seq_MCF-7_Human1.69388875
44SOX2_22085726_ChIP-Seq_NPCs_Mouse1.67843185
45MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.64013758
46MYC_19829295_ChIP-Seq_ESCs_Human1.62487393
47GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse1.59450113
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.57266683
49* GATA3_21867929_ChIP-Seq_CD8_Mouse1.56594034
50OCT4_20526341_ChIP-Seq_ESCs_Human1.54936609
51* TP63_22573176_ChIP-Seq_HFKS_Human1.54061441
52RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.53874755
53SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.50416356
54UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.49240173
55WDR5_24793694_ChIP-Seq_LNCAP_Human1.46741055
56PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.46606184
57AUTS2_25519132_ChIP-Seq_293T-REX_Human1.46564591
58P300_27268052_Chip-Seq_Bcells_Human1.46507983
59KDM2B_26808549_Chip-Seq_REH_Human1.46388883
60KAP1_22055183_ChIP-Seq_ESCs_Mouse1.45555337
61TAL1_26923725_Chip-Seq_HPCs_Mouse1.41824457
62SMAD4_21741376_ChIP-Seq_EPCs_Human1.39590329
63ER_23166858_ChIP-Seq_MCF-7_Human1.39295703
64LUZP1_20508642_ChIP-Seq_ESCs_Mouse1.38133882
65PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.37802558
66* FLI1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.37151800
67CBP_20019798_ChIP-Seq_JUKART_Human1.37023155
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.37023155
69CBX2_27304074_Chip-Seq_ESCs_Mouse1.36590418
70P53_21459846_ChIP-Seq_SAOS-2_Human1.36433620
71SUZ12_27294783_Chip-Seq_ESCs_Mouse1.35597301
72MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34888921
73SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.34467252
74TP63_19390658_ChIP-ChIP_HaCaT_Human1.34284598
75ETV2_25802403_ChIP-Seq_MESCs_Mouse1.34114889
76ARNT_22903824_ChIP-Seq_MCF-7_Human1.34081981
77SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.31048562
78ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.30434227
79GATA3_21867929_ChIP-Seq_TH1_Mouse1.30105721
80HNFA_21074721_ChIP-Seq_CACO-2_Human1.27898494
81REST_21632747_ChIP-Seq_MESCs_Mouse1.26138120
82AR_25329375_ChIP-Seq_VCAP_Human1.24619950
83CBX2_22325352_ChIP-Seq_293T-Rex_Human1.24449487
84GATA3_21878914_ChIP-Seq_MCF-7_Human1.24433247
85FLI1_21867929_ChIP-Seq_TH2_Mouse1.24389476
86TP53_18474530_ChIP-ChIP_U2OS_Human1.24305696
87RBPJ_21746931_ChIP-Seq_IB4_Human1.24036184
88CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.23813121
89PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22917486
90GF1_26923725_Chip-Seq_HPCs_Mouse1.22442578
91NFE2_27457419_Chip-Seq_LIVER_Mouse1.21932468
92PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21236526
93RAD21_21589869_ChIP-Seq_MESCs_Mouse1.21070201
94* P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.20693583
95CEBPB_22108803_ChIP-Seq_LS180_Human1.20344364
96CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.20169152
97CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19580288
98SMAD3_21741376_ChIP-Seq_ESCs_Human1.19559156
99* SA1_27219007_Chip-Seq_Bcells_Human1.19444985
100TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.17910130
101SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.17690272
102TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.17384444
103CTBP2_25329375_ChIP-Seq_LNCAP_Human1.16920483
104SPI1_26923725_Chip-Seq_HPCs_Mouse1.16630890
105ETV1_20927104_ChIP-Seq_GIST48_Human1.16118089
106EZH2_27294783_Chip-Seq_ESCs_Mouse1.14654654
107ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.14218418
108SETDB1_19884257_ChIP-Seq_MESCs_Mouse1.13726778
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.11954211
110RUNX1_26923725_Chip-Seq_HPCs_Mouse1.11166754
111POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10608823
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10608823
113EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.09945009
114SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09673031
115RXRA_24833708_ChIP-Seq_LIVER_Mouse1.09054958
116* SA1_27219007_Chip-Seq_ERYTHROID_Human1.08983311
117PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.08097173
118RUNX_20019798_ChIP-Seq_JUKART_Human1.07963894
119ERG_20517297_ChIP-Seq_VCAP_Human1.07164805
120RARA_24833708_ChIP-Seq_LIVER_Mouse1.07012778
121MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.06826744
122YY1_22570637_ChIP-Seq_MALME-3M_Human1.06809710
123ESET_19884257_ChIP-Seq_ESCs_Mouse1.06631399
124SMAD3_21741376_ChIP-Seq_EPCs_Human1.06323053
125TET1_21451524_ChIP-Seq_MESCs_Mouse1.06175057
126CRX_20693478_ChIP-Seq_RETINA_Mouse1.05875689
127GATA1_19941827_ChIP-Seq_MEL86_Mouse1.05714559
128MYC_27129775_Chip-Seq_CORNEA_Mouse1.05522618
129CSB_26484114_Chip-Seq_FIBROBLAST_Human1.03519891
130RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.03238563
131SMRT_27268052_Chip-Seq_Bcells_Human1.03046876
132EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.02997366
133NANOG_18555785_Chip-Seq_ESCs_Mouse1.02861873
134NFIB_24661679_ChIP-Seq_LUNG_Mouse1.02811472
135TBL1_22424771_ChIP-Seq_293T_Human1.02752040
136THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.02661075
137SMAD4_21741376_ChIP-Seq_HESCs_Human1.02454702
138RUNX1_27514584_Chip-Seq_MCF-7_Human1.02252969
139CTCF_21964334_Chip-Seq_Bcells_Human1.01109735
140GATA6_21074721_ChIP-Seq_CACO-2_Human1.00969323
141OCT4_19829295_ChIP-Seq_ESCs_Human1.00935423
142NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.00879964
143PHF8_20622853_ChIP-Seq_HELA_Human1.00536358
144KLF4_19829295_ChIP-Seq_ESCs_Human0.99673866
145CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.99369356
146JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.99234832
147E2F1_17053090_ChIP-ChIP_MCF-7_Human0.99180725
148LDB1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98774655
149PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97829503
150SPI1_20517297_ChIP-Seq_HL60_Human0.97697131
151SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.97606753
152TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97473053
153OCT4_18555785_Chip-Seq_ESCs_Mouse0.96946466
154PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.96736541
155P300_19829295_ChIP-Seq_ESCs_Human0.96155290
156SOX11_22085726_ChIP-Seq_ESNs_Mouse0.94968964
157FLI1_21867929_ChIP-Seq_CD8_Mouse0.94676993
158ELF1_20517297_ChIP-Seq_JURKAT_Human0.93980517
159P53_22387025_ChIP-Seq_ESCs_Mouse0.93318969
160CTCF_20526341_ChIP-Seq_ESCs_Human0.92651459
161KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse0.90278485
162SOX9_26525672_Chip-Seq_HEART_Mouse0.90203881
163CMYC_18555785_Chip-Seq_ESCs_Mouse0.90025883
164TAF15_26573619_Chip-Seq_HEK293_Human0.89250004
165MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.89222921
166SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.89125244
167EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.88896471
168BCOR_27268052_Chip-Seq_Bcells_Human0.88750723
169NFYB_21822215_ChIP-Seq_K562_Human0.87970800
170OCT4_21477851_ChIP-Seq_ESCs_Mouse0.87447128
171KLF4_18555785_Chip-Seq_ESCs_Mouse0.87022256
172RNF2_27304074_Chip-Seq_NSC_Mouse0.86985401

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003698_abnormal_male_reproductive6.09262543
2MP0001929_abnormal_gametogenesis5.59375609
3MP0008877_abnormal_DNA_methylation4.01683822
4MP0002210_abnormal_sex_determination3.38322616
5MP0002161_abnormal_fertility/fecundity3.32542529
6MP0005670_abnormal_white_adipose2.89338929
7MP0001145_abnormal_male_reproductive2.88511844
8MP0000678_abnormal_parathyroid_gland2.58097316
9MP0000653_abnormal_sex_gland2.49501085
10MP0002653_abnormal_ependyma_morphology2.21050822
11MP0003718_maternal_effect2.17652859
12MP0005423_abnormal_somatic_nervous2.15446458
13MP0005410_abnormal_fertilization16.6453505
14MP0002249_abnormal_larynx_morphology1.64487382
15MP0005379_endocrine/exocrine_gland_phen1.59513387
16MP0002160_abnormal_reproductive_system1.56898786
17MP0004233_abnormal_muscle_weight1.49692452
18MP0003646_muscle_fatigue1.43651464
19MP0005623_abnormal_meninges_morphology1.42923881
20MP0009053_abnormal_anal_canal1.42254196
21MP0005310_abnormal_salivary_gland1.36435275
22MP0001486_abnormal_startle_reflex1.35819048
23MP0001485_abnormal_pinna_reflex1.34090047
24MP0004510_myositis1.32863360
25MP0002822_catalepsy1.31065523
26MP0002735_abnormal_chemical_nociception1.30014325
27MP0002282_abnormal_trachea_morphology1.13862844
28MP0002138_abnormal_hepatobiliary_system1.13814968
29MP0004859_abnormal_synaptic_plasticity1.11302040
30MP0001765_abnormal_ion_homeostasis1.06854562
31MP0005083_abnormal_biliary_tract1.03011131
32MP0008058_abnormal_DNA_repair1.02348012
33MP0001963_abnormal_hearing_physiology1.00689152
34MP0005248_abnormal_Harderian_gland0.98075594
35MP0002234_abnormal_pharynx_morphology0.97369927
36MP0002127_abnormal_cardiovascular_syste0.97184921
37MP0001984_abnormal_olfaction0.97031261
38MP0005395_other_phenotype0.95713147
39MP0005451_abnormal_body_composition0.93877531
40MP0000026_abnormal_inner_ear0.91038378
41MP0005647_abnormal_sex_gland0.88806270
42MP0000681_abnormal_thyroid_gland0.83811097
43MP0000955_abnormal_spinal_cord0.79317709
44MP0002229_neurodegeneration0.78522498
45MP0005389_reproductive_system_phenotype0.77865520
46MP0009046_muscle_twitch0.77339372
47MP0000049_abnormal_middle_ear0.74064203
48MP0003115_abnormal_respiratory_system0.71582888
49MP0000516_abnormal_urinary_system0.68984557
50MP0005367_renal/urinary_system_phenotyp0.68984557
51MP0008569_lethality_at_weaning0.68110609
52MP0002067_abnormal_sensory_capabilities0.66514561
53MP0008995_early_reproductive_senescence0.65373779
54MP0002733_abnormal_thermal_nociception0.65278003
55MP0001879_abnormal_lymphatic_vessel0.64859381
56MP0004085_abnormal_heartbeat0.64040707
57MP0003011_delayed_dark_adaptation0.63179378
58MP0000003_abnormal_adipose_tissue0.61466987
59MP0001905_abnormal_dopamine_level0.60643815
60MP0002557_abnormal_social/conspecific_i0.59845926
61MP0005636_abnormal_mineral_homeostasis0.59121406
62MP0010094_abnormal_chromosome_stability0.58890536
63MP0005377_hearing/vestibular/ear_phenot0.55701718
64MP0003878_abnormal_ear_physiology0.55701718
65MP0001293_anophthalmia0.53598371
66MP0005666_abnormal_adipose_tissue0.53399692
67MP0003137_abnormal_impulse_conducting0.52334614
68MP0001970_abnormal_pain_threshold0.52288516
69MP0004036_abnormal_muscle_relaxation0.52179430
70MP0004484_altered_response_of0.50005737
71MP0000358_abnormal_cell_content/0.49877593
72MP0001324_abnormal_eye_pigmentation0.49519704
73MP0002572_abnormal_emotion/affect_behav0.49177914
74MP0005167_abnormal_blood-brain_barrier0.49130598
75MP0003329_amyloid_beta_deposits0.48408369
76MP0003699_abnormal_female_reproductive0.48209910
77MP0002269_muscular_atrophy0.48072900
78MP0000470_abnormal_stomach_morphology0.47393760
79MP0002734_abnormal_mechanical_nocicepti0.46862336
80MP0001764_abnormal_homeostasis0.46644672
81MP0001666_abnormal_nutrient_absorption0.46481896
82MP0005084_abnormal_gallbladder_morpholo0.45556295
83MP0004133_heterotaxia0.44310713
84MP0002272_abnormal_nervous_system0.43616301
85MP0005397_hematopoietic_system_phenotyp0.43572338
86MP0001545_abnormal_hematopoietic_system0.43572338
87MP0003111_abnormal_nucleus_morphology0.43157534
88MP0002254_reproductive_system_inflammat0.42966137
89MP0005535_abnormal_body_temperature0.42900937
90MP0006036_abnormal_mitochondrial_physio0.42847881
91MP0002736_abnormal_nociception_after0.42476581
92MP0003119_abnormal_digestive_system0.42466304
93MP0000569_abnormal_digit_pigmentation0.42397162
94MP0000534_abnormal_ureter_morphology0.41070284
95MP0002928_abnormal_bile_duct0.39919147
96MP0008961_abnormal_basal_metabolism0.39866644
97MP0003091_abnormal_cell_migration0.38936763
98MP0009745_abnormal_behavioral_response0.38112589
99MP0009278_abnormal_bone_marrow0.37860054
100MP0000249_abnormal_blood_vessel0.37183544
101MP0001730_embryonic_growth_arrest0.36208944
102MP0000613_abnormal_salivary_gland0.36196313
103MP0005253_abnormal_eye_physiology0.36152904
104MP0009697_abnormal_copulation0.35814794
105MP0009115_abnormal_fat_cell0.34882892
106MP0001270_distended_abdomen0.34596856
107MP0005332_abnormal_amino_acid0.33829662
108MP0005551_abnormal_eye_electrophysiolog0.31995679
109MP0003950_abnormal_plasma_membrane0.31544864
110MP0005391_vision/eye_phenotype0.30976456
111MP0003936_abnormal_reproductive_system0.30762787
112MP0008057_abnormal_DNA_replication0.30620086
113MP0003880_abnormal_central_pattern0.30563029
114MP0003635_abnormal_synaptic_transmissio0.30149081
115MP0003942_abnormal_urinary_system0.29860958
116MP0001119_abnormal_female_reproductive0.29612378
117MP0001873_stomach_inflammation0.29600849
118MP0010307_abnormal_tumor_latency0.29324987
119MP0001440_abnormal_grooming_behavior0.29312603
120MP0008007_abnormal_cellular_replicative0.27511735
121MP0003786_premature_aging0.27163819
122MP0004811_abnormal_neuron_physiology0.27057565
123MP0003633_abnormal_nervous_system0.26321299
124MP0003861_abnormal_nervous_system0.26216208
125MP0002139_abnormal_hepatobiliary_system0.25391636
126MP0002971_abnormal_brown_adipose0.24856234
127MP0002169_no_abnormal_phenotype0.24117694
128MP0002873_normal_phenotype0.23846118
129MP0002102_abnormal_ear_morphology0.23581674
130MP0004019_abnormal_vitamin_homeostasis0.23299041
131MP0000604_amyloidosis0.23269017
132MP0001849_ear_inflammation0.21837500
133MP0002152_abnormal_brain_morphology0.20897672
134MP0003948_abnormal_gas_homeostasis0.20815029
135MP0003631_nervous_system_phenotype0.20583492
136MP0006035_abnormal_mitochondrial_morpho0.20290916
137MP0002092_abnormal_eye_morphology0.20193541
138MP0000313_abnormal_cell_death0.19934259
139MP0002084_abnormal_developmental_patter0.19153829
140MP0001968_abnormal_touch/_nociception0.19069261
141MP0003879_abnormal_hair_cell0.18963133
142MP0003787_abnormal_imprinting0.18513738
143MP0005380_embryogenesis_phenotype0.16895894
144MP0001672_abnormal_embryogenesis/_devel0.16895894
145MP0004808_abnormal_hematopoietic_stem0.16073910
146MP0004145_abnormal_muscle_electrophysio0.16063724
147MP0002295_abnormal_pulmonary_circulatio0.16049394
148MP0001697_abnormal_embryo_size0.15211597
149MP0000001_mammalian_phenotype0.14647644
150MP0004742_abnormal_vestibular_system0.14476068
151MP0005375_adipose_tissue_phenotype0.14080195
152MP0002132_abnormal_respiratory_system0.13014767
153MP0005319_abnormal_enzyme/_coenzyme0.12795424
154MP0001727_abnormal_embryo_implantation0.12242759
155MP0002080_prenatal_lethality0.12210929
156MP0001348_abnormal_lacrimal_gland0.12176293
157MP0000462_abnormal_digestive_system0.12145942
158MP0002405_respiratory_system_inflammati0.12058438
159MP0003984_embryonic_growth_retardation0.12033946
160MP0004084_abnormal_cardiac_muscle0.11567829
161MP0003077_abnormal_cell_cycle0.11249512

Predicted human phenotypes

RankGene SetZ-score
1Abnormal respiratory motile cilium physiology (HP:0012261)9.42453657
2Abnormal respiratory epithelium morphology (HP:0012253)9.24672809
3Abnormal respiratory motile cilium morphology (HP:0005938)9.24672809
4Severe visual impairment (HP:0001141)8.50819231
5Rhinitis (HP:0012384)7.54947437
6Chronic bronchitis (HP:0004469)7.52134128
7Abnormal ciliary motility (HP:0012262)7.42882944
8Infertility (HP:0000789)6.98779258
9Nasal polyposis (HP:0100582)6.47520937
10Attenuation of retinal blood vessels (HP:0007843)5.83295774
11Bony spicule pigmentary retinopathy (HP:0007737)5.58054775
12Abnormality of the nasal mucosa (HP:0000433)5.32265612
13Male infertility (HP:0003251)4.82945486
14Bronchitis (HP:0012387)4.65465111
15Chronic hepatic failure (HP:0100626)4.56972745
16Bronchiectasis (HP:0002110)4.43911141
17Resting tremor (HP:0002322)4.42683773
18Hyperkalemia (HP:0002153)4.35461041
19Parkinsonism with favorable response to dopaminergic medication (HP:0002548)4.24705053
20Abnormal rod and cone electroretinograms (HP:0008323)4.14861960
21Nephronophthisis (HP:0000090)4.10216348
22Abnormality of macular pigmentation (HP:0008002)3.93237893
23Enlarged epiphyses (HP:0010580)3.91528655
24Facial shape deformation (HP:0011334)3.85267505
25Potter facies (HP:0002009)3.85267505
26Hypoplastic ischia (HP:0003175)3.71655140
27Abnormal spermatogenesis (HP:0008669)3.71310334
28Cone-rod dystrophy (HP:0000548)3.57895512
29Aplasia/Hypoplasia of the earlobes (HP:0009906)3.50211888
30Recurrent sinusitis (HP:0011108)3.33696873
31Recurrent otitis media (HP:0000403)3.32711917
32Abnormality of the ischium (HP:0003174)3.29658938
33Hypoplasia of the thymus (HP:0000778)3.12702237
34Unilateral renal agenesis (HP:0000122)3.10550221
35Abnormality of the renal medulla (HP:0100957)3.06677266
36Progressive sensorineural hearing impairment (HP:0000408)2.99436787
37Hypoalphalipoproteinemia (HP:0003233)2.97015458
38Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.93048961
39Postural instability (HP:0002172)2.82919478
40Abnormality of the aortic arch (HP:0012303)2.76262444
41Recurrent bronchitis (HP:0002837)2.74352433
42Abnormality of the costochondral junction (HP:0000919)2.73943022
43Generalized aminoaciduria (HP:0002909)2.69598166
44Tubulointerstitial nephritis (HP:0001970)2.69390705
45Impulsivity (HP:0100710)2.67693330
46Abnormality of midbrain morphology (HP:0002418)2.60718309
47Molar tooth sign on MRI (HP:0002419)2.60718309
48Truncal obesity (HP:0001956)2.57755964
49Tubular atrophy (HP:0000092)2.57286131
50Amelogenesis imperfecta (HP:0000705)2.50401843
51Abnormality of potassium homeostasis (HP:0011042)2.50129248
52Abnormality of dental color (HP:0011073)2.45912864
53Medial flaring of the eyebrow (HP:0010747)2.40809282
54Renovascular hypertension (HP:0100817)2.38966763
55Progressive cerebellar ataxia (HP:0002073)2.36599851
56Tubulointerstitial abnormality (HP:0001969)2.35997948
57Abnormality of the hepatic vasculature (HP:0006707)2.35160861
58Portal hypertension (HP:0001409)2.34583386
59Azoospermia (HP:0000027)2.34469309
60Menstrual irregularities (HP:0000858)2.34395744
61Cholecystitis (HP:0001082)2.33631687
62Abnormal gallbladder physiology (HP:0012438)2.33631687
63Insulin-resistant diabetes mellitus (HP:0000831)2.31709213
64Widely patent fontanelles and sutures (HP:0004492)2.29991660
65Flattened epiphyses (HP:0003071)2.29442070
66Renal Fanconi syndrome (HP:0001994)2.28220336
67Polyuria (HP:0000103)2.22099687
68Hypophosphatemic rickets (HP:0004912)2.21402828
69Gonadotropin excess (HP:0000837)2.20419602
70Hyponatremia (HP:0002902)2.14709004
71Abnormality of the parathyroid morphology (HP:0011766)2.13837143
72Dyschromatopsia (HP:0007641)2.12818594
73Ventricular tachycardia (HP:0004756)2.09315499
74Osteomalacia (HP:0002749)2.05463214
75Epiphyseal dysplasia (HP:0002656)2.03368438
76Abnormality of the epiphysis of the femoral head (HP:0010574)2.02008135
77Dynein arm defect of respiratory motile cilia (HP:0012255)13.4440334
78Absent/shortened dynein arms (HP:0200106)13.4440334
79Respiratory insufficiency due to defective ciliary clearance (HP:0200073)13.2373372
80Tetany (HP:0001281)1.95904785
81Flat capital femoral epiphysis (HP:0003370)1.95284897
82Tubulointerstitial fibrosis (HP:0005576)1.94785906
83Aplasia/Hypoplasia of the sacrum (HP:0008517)1.93723792
84Decreased central vision (HP:0007663)1.90086383
85Choroideremia (HP:0001139)1.88023495
86Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.87508952
87Abnormality of femoral epiphyses (HP:0006499)1.87508952
88Progressive hearing impairment (HP:0001730)1.86796454
89Focal segmental glomerulosclerosis (HP:0000097)1.86443888
90Hypoparathyroidism (HP:0000829)1.84534435
91Bradycardia (HP:0001662)1.82567604
92Recurrent corneal erosions (HP:0000495)1.82324943
93Abnormality of the pubic bones (HP:0003172)1.82079341
94Myokymia (HP:0002411)1.81253879
95Transposition of the great arteries (HP:0001669)1.79902438
96Abnormal connection of the cardiac segments (HP:0011545)1.79902438
97Abnormal ventriculo-arterial connection (HP:0011563)1.79902438
98Abnormality of the femoral head (HP:0003368)1.79859466
99Spastic tetraparesis (HP:0001285)1.79646826
100Pendular nystagmus (HP:0012043)1.79110949
101Postaxial foot polydactyly (HP:0001830)1.78276138
102Abnormal albumin level (HP:0012116)1.78143046
103Hypoalbuminemia (HP:0003073)1.78143046
104Hyperthyroidism (HP:0000836)1.77993617
105Abnormal drinking behavior (HP:0030082)1.74298303
106Polydipsia (HP:0001959)1.74298303
107Stage 5 chronic kidney disease (HP:0003774)1.73899942
108Double outlet right ventricle (HP:0001719)1.73101065
109Congenital malformation of the right heart (HP:0011723)1.73101065
110Congenital hepatic fibrosis (HP:0002612)1.66756780
111Abnormality of renal excretion (HP:0011036)1.63730976
112Abnormal biliary tract physiology (HP:0012439)1.63520600
113Bile duct proliferation (HP:0001408)1.63520600
114Hemorrhage of the eye (HP:0011885)1.63433068
115Heterotopia (HP:0002282)1.62564434
116Hypoplasia of the capital femoral epiphysis (HP:0003090)1.61896562
117Abnormality of the renal cortex (HP:0011035)1.58783978
118Short ribs (HP:0000773)1.55966713
119Asymmetric septal hypertrophy (HP:0001670)1.51759080
120Oculomotor apraxia (HP:0000657)1.50160035
121Bell-shaped thorax (HP:0001591)1.49472377
122Decreased electroretinogram (ERG) amplitude (HP:0000654)1.49429168
123Aplasia/Hypoplasia of the lens (HP:0008063)1.48284460
124Neurofibrillary tangles (HP:0002185)1.47971716
125Abnormality of permanent molar morphology (HP:0011071)1.44691897
126Abnormality of the dental root (HP:0006486)1.44691897
127Taurodontia (HP:0000679)1.44691897
128Fibular hypoplasia (HP:0003038)1.44100879
129Renal dysplasia (HP:0000110)1.43001047
130Abnormality of dentin (HP:0010299)1.41199489
131Postaxial hand polydactyly (HP:0001162)1.40710851
132Facial cleft (HP:0002006)1.40369490
133Bundle branch block (HP:0011710)1.39998628
134Cystic liver disease (HP:0006706)1.37974195
135Abnormal urine output (HP:0012590)1.35461727
136Abnormality of the dental pulp (HP:0006479)1.35291180
137Chronic sinusitis (HP:0011109)1.33884833
138Easy fatigability (HP:0003388)1.33847367
139Abnormality of the lower motor neuron (HP:0002366)1.33798042
140Abnormality of molar morphology (HP:0011070)1.33123865
141Abnormality of molar (HP:0011077)1.33123865
142Deformed sella turcica (HP:0002681)1.32678908
143Exercise-induced myalgia (HP:0003738)1.31806013
144Pancreatic fibrosis (HP:0100732)1.30261264
145Constricted visual fields (HP:0001133)1.29411146
146Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.28929901
147Absent epiphyses (HP:0010577)1.26340059
148Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.26340059
149Congenital primary aphakia (HP:0007707)1.25295623
150Myoglobinuria (HP:0002913)1.24937595
151Gait imbalance (HP:0002141)1.24552634
152Cerebellar dysplasia (HP:0007033)1.23881001
153Absent frontal sinuses (HP:0002688)1.23692890
154Fatigable weakness (HP:0003473)1.22828297
155Abnormality of the neuromuscular junction (HP:0003398)1.22828297
156Microglossia (HP:0000171)1.21635583
157Cerebral inclusion bodies (HP:0100314)1.21054497
158Sensory axonal neuropathy (HP:0003390)1.20819958
159Abnormality of saccadic eye movements (HP:0000570)1.19338878
160Amyotrophic lateral sclerosis (HP:0007354)1.18240711
161Aplasia/Hypoplasia of the tongue (HP:0010295)1.17213267
162Broad distal phalanx of finger (HP:0009836)1.17021219
163Loss of speech (HP:0002371)1.16525539
164Rhabdomyolysis (HP:0003201)1.15622508
165Hypercholesterolemia (HP:0003124)1.14171183
166Abnormality of ocular smooth pursuit (HP:0000617)1.13417475

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK38.32404681
2PDK48.32404681
3TESK16.29107906
4PDK25.38433278
5DDR24.87018447
6PRKD34.84174774
7ICK4.40704245
8MAP4K23.67619988
9INSRR3.65918399
10BRD43.04031605
11PLK22.88243571
12PTK2B2.23629194
13WNK42.09919880
14STK392.01438571
15STK381.82788287
16MST1R1.81387970
17PNCK1.66514754
18NEK21.65193354
19PIK3CG1.58641288
20DYRK1B1.54371342
21CDK71.27071654
22PDK11.24976893
23KSR21.09333906
24MAP3K91.07809197
25DYRK30.93510977
26SIK20.88261034
27LATS20.83824674
28CAMK1D0.82576103
29TYRO30.82230558
30AKT30.80854869
31MAP3K110.79616652
32PDPK10.78483480
33IRAK10.78396006
34RPS6KA20.77090068
35UHMK10.75370459
36WNK10.75274122
37MAPK150.74676608
38CCNB10.72432990
39PASK0.72247622
40EEF2K0.70466393
41RIPK40.67648316
42MAP2K20.65184554
43TTK0.65138598
44TESK20.64880638
45MAP3K80.61810796
46STK30.61475490
47CHEK20.61240712
48PRKAA20.60284727
49MAP3K20.57497368
50ROCK10.53327801
51PINK10.53325588
52MAP2K60.53054524
53STK38L0.51678621
54CAMK10.49456629
55LMTK20.49273203
56SGK2230.46415216
57SGK4940.46415216
58CDK30.44677108
59RPS6KC10.44324502
60RPS6KL10.44324502
61ARAF0.43077657
62IRAK20.42940582
63MAP3K100.42485593
64PAK10.41742802
65RPS6KA60.41312894
66CHEK10.40580403
67MAPK10.39712427
68MUSK0.38514401
69CAMK40.38389581
70BMPR1B0.38192318
71CAMK1G0.37519553
72NTRK20.37516030
73MAP3K10.36507055
74BLK0.36332091
75PRKCG0.35996889
76WEE10.34848471
77MARK10.32769797
78LATS10.32350677
79BRSK20.30450887
80NTRK30.27792368
81PAK20.27742576
82SGK10.27714706
83ATM0.27654127
84ATR0.27139954
85PAK40.26715778
86MTOR0.24533874
87TLK10.24521599
88TIE10.24312573
89PLK40.24289780
90MAPK140.23947680
91MAPK110.23432461
92MAPKAPK50.23286615
93MARK20.22598392
94CDC70.22443555
95MET0.22108510
96CAMKK10.20938602
97MAPK100.20734403
98PRKCZ0.19561273
99PLK10.18133576
100MAP3K40.17949375
101PRKAA10.17270500
102NEK60.17229888
103AKT10.17225354
104CDK150.16952812
105BRSK10.16697705
106ZAK0.15560882
107RPS6KB10.15156804
108PRKCQ0.14557791
109CDK180.14272995
110CDK11A0.13016518
111IKBKB0.12993934
112PRKG20.11871514
113BRAF0.11138599
114CSNK2A10.09862179
115STK100.09445369
116CDK140.09309888
117RPS6KA10.08654991
118MARK30.08259440
119OXSR10.08052904
120GSK3B0.06827892
121SGK20.06690501
122PIM10.05961946
123MAPK90.05908037
124CDK120.05643717
125CSF1R0.05500824
126CDK20.05457719
127FER0.04732270
128CDK10.04423491
129CHUK0.04334690
130CDK60.04331685
131AURKA0.04097480
132BUB10.04095358
133CSNK2A20.04014978
134MAPK80.03706443
135PRKCD0.03584694
136PRKACG0.03130475
137ACVR1B0.03023530
138PRKG10.02496673
139ZAP700.02450766
140PKN10.01379640
141STK110.01362363
142PRKCB0.01005207
143CSNK1D0.00975768
144CLK10.00427730
145PRKACA-0.0455832
146WNK3-0.0433599
147PRKACB-0.0400157
148PRKDC-0.0323466
149RPS6KA3-0.0317011
150EGFR-0.0204464
151PDGFRB-0.0195592
152MAP3K5-0.0149033
153CDK4-0.0066867
154CAMK2A-0.0016248
155PRKCA-0.0013308

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000728.20989212
2Fatty acid biosynthesis_Homo sapiens_hsa000614.62778811
3Glycolysis / Gluconeogenesis_Homo sapiens_hsa000104.55156837
4Vitamin B6 metabolism_Homo sapiens_hsa007503.64187807
5Olfactory transduction_Homo sapiens_hsa047403.49686715
6Pyruvate metabolism_Homo sapiens_hsa006203.47145076
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.13005240
8Linoleic acid metabolism_Homo sapiens_hsa005913.05195757
9Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.69965805
10Glucagon signaling pathway_Homo sapiens_hsa049222.62248960
11Butanoate metabolism_Homo sapiens_hsa006502.60944208
12Propanoate metabolism_Homo sapiens_hsa006402.60903530
13Basal transcription factors_Homo sapiens_hsa030222.40759245
14Carbohydrate digestion and absorption_Homo sapiens_hsa049732.30510103
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.16126079
16Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.04059543
17Selenocompound metabolism_Homo sapiens_hsa004502.03075898
18Glycerolipid metabolism_Homo sapiens_hsa005611.91775474
19Pentose phosphate pathway_Homo sapiens_hsa000301.82797758
20PPAR signaling pathway_Homo sapiens_hsa033201.80965481
21Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.79161707
22Allograft rejection_Homo sapiens_hsa053301.79052716
23Type I diabetes mellitus_Homo sapiens_hsa049401.77496263
24Autoimmune thyroid disease_Homo sapiens_hsa053201.73218577
25Oocyte meiosis_Homo sapiens_hsa041141.69631680
26Glycerophospholipid metabolism_Homo sapiens_hsa005641.69435993
27Graft-versus-host disease_Homo sapiens_hsa053321.63797705
28Fructose and mannose metabolism_Homo sapiens_hsa000511.60875825
29Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.59652628
30Glycosaminoglycan degradation_Homo sapiens_hsa005311.58513490
31Type II diabetes mellitus_Homo sapiens_hsa049301.54516354
32Fat digestion and absorption_Homo sapiens_hsa049751.52378186
33Phenylalanine metabolism_Homo sapiens_hsa003601.50818925
34Mineral absorption_Homo sapiens_hsa049781.50175336
35Amphetamine addiction_Homo sapiens_hsa050311.49612949
36Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.44050445
37Carbon metabolism_Homo sapiens_hsa012001.44038312
38Ether lipid metabolism_Homo sapiens_hsa005651.40852506
39Fatty acid degradation_Homo sapiens_hsa000711.32357599
40Fatty acid metabolism_Homo sapiens_hsa012121.31343614
41Cardiac muscle contraction_Homo sapiens_hsa042601.31032839
42Dorso-ventral axis formation_Homo sapiens_hsa043201.30414561
43Fanconi anemia pathway_Homo sapiens_hsa034601.30161416
44Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.25948725
45Viral myocarditis_Homo sapiens_hsa054161.24806714
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.22807759
47Arginine and proline metabolism_Homo sapiens_hsa003301.22663561
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.13365256
49Antigen processing and presentation_Homo sapiens_hsa046121.10248743
50Phototransduction_Homo sapiens_hsa047441.08865436
51Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06840034
52Purine metabolism_Homo sapiens_hsa002301.06749613
53mRNA surveillance pathway_Homo sapiens_hsa030151.05054626
54Glutathione metabolism_Homo sapiens_hsa004801.03672085
55Renin secretion_Homo sapiens_hsa049241.01714745
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.99746148
57Biosynthesis of amino acids_Homo sapiens_hsa012300.96922416
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.96008796
59Arginine biosynthesis_Homo sapiens_hsa002200.95617708
60Nicotine addiction_Homo sapiens_hsa050330.93816397
61Huntingtons disease_Homo sapiens_hsa050160.92855601
62Collecting duct acid secretion_Homo sapiens_hsa049660.92002509
63RNA transport_Homo sapiens_hsa030130.91425960
64Hedgehog signaling pathway_Homo sapiens_hsa043400.91000508
65Morphine addiction_Homo sapiens_hsa050320.88524777
66Influenza A_Homo sapiens_hsa051640.81568894
67Arachidonic acid metabolism_Homo sapiens_hsa005900.80389876
68Chemical carcinogenesis_Homo sapiens_hsa052040.80106511
69Adipocytokine signaling pathway_Homo sapiens_hsa049200.77132712
70Insulin secretion_Homo sapiens_hsa049110.76399385
71Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.72960881
72Systemic lupus erythematosus_Homo sapiens_hsa053220.72902906
73Long-term potentiation_Homo sapiens_hsa047200.72016698
74Thyroid hormone synthesis_Homo sapiens_hsa049180.71376599
75Estrogen signaling pathway_Homo sapiens_hsa049150.71085066
76Bile secretion_Homo sapiens_hsa049760.69833067
77Renin-angiotensin system_Homo sapiens_hsa046140.68437538
78cGMP-PKG signaling pathway_Homo sapiens_hsa040220.65915094
79Central carbon metabolism in cancer_Homo sapiens_hsa052300.65402687
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.64655279
81Tyrosine metabolism_Homo sapiens_hsa003500.60121115
82Legionellosis_Homo sapiens_hsa051340.59230999
83Aldosterone synthesis and secretion_Homo sapiens_hsa049250.57969695
84Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.55432415
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.52592170
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.51971148
87Glutamatergic synapse_Homo sapiens_hsa047240.50573611
88Pancreatic secretion_Homo sapiens_hsa049720.50201413
89Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.49248880
90Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48465220
91MAPK signaling pathway_Homo sapiens_hsa040100.48067817
92Maturity onset diabetes of the young_Homo sapiens_hsa049500.47920577
93Retinol metabolism_Homo sapiens_hsa008300.46746790
94Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.46662626
95Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.45747082
96Protein digestion and absorption_Homo sapiens_hsa049740.45591985
97Calcium signaling pathway_Homo sapiens_hsa040200.44631461
98AMPK signaling pathway_Homo sapiens_hsa041520.43820965
99Salivary secretion_Homo sapiens_hsa049700.43550521
100Endocytosis_Homo sapiens_hsa041440.42797804
101Synaptic vesicle cycle_Homo sapiens_hsa047210.42396702
102Vascular smooth muscle contraction_Homo sapiens_hsa042700.40683549
103ABC transporters_Homo sapiens_hsa020100.40420365
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.40041311
105Acute myeloid leukemia_Homo sapiens_hsa052210.39057883
106Pyrimidine metabolism_Homo sapiens_hsa002400.38821996
107Inositol phosphate metabolism_Homo sapiens_hsa005620.38612027
108Cholinergic synapse_Homo sapiens_hsa047250.38016082
109Metabolic pathways_Homo sapiens_hsa011000.37097442
110Phosphatidylinositol signaling system_Homo sapiens_hsa040700.36472744
111Alcoholism_Homo sapiens_hsa050340.36052189
112VEGF signaling pathway_Homo sapiens_hsa043700.35757781
113Sulfur relay system_Homo sapiens_hsa041220.35734507
114Tight junction_Homo sapiens_hsa045300.34808961
115Gastric acid secretion_Homo sapiens_hsa049710.33674201
116Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.33522652
117Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.33475749
118Serotonergic synapse_Homo sapiens_hsa047260.32705003
119Sulfur metabolism_Homo sapiens_hsa009200.32351812
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.27838976
121GABAergic synapse_Homo sapiens_hsa047270.26881311
122cAMP signaling pathway_Homo sapiens_hsa040240.24895315
123Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24110223
124Herpes simplex infection_Homo sapiens_hsa051680.21101943
125Nitrogen metabolism_Homo sapiens_hsa009100.19614845
126Taste transduction_Homo sapiens_hsa047420.19410754
127Oxytocin signaling pathway_Homo sapiens_hsa049210.19283161
128Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18836019
129Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.17966745
130Cocaine addiction_Homo sapiens_hsa050300.16550495
131Circadian entrainment_Homo sapiens_hsa047130.15059978
132Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.15026558
133Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.14638804
134Prolactin signaling pathway_Homo sapiens_hsa049170.13772054
135HIF-1 signaling pathway_Homo sapiens_hsa040660.13490527
136B cell receptor signaling pathway_Homo sapiens_hsa046620.13442394
137Viral carcinogenesis_Homo sapiens_hsa052030.12166649
138Wnt signaling pathway_Homo sapiens_hsa043100.11454574
139DNA replication_Homo sapiens_hsa030300.11399646
140Salmonella infection_Homo sapiens_hsa051320.11025144
141Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.09898125
142Basal cell carcinoma_Homo sapiens_hsa052170.07920503

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