RNF152

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)5.59872960
2nucleobase catabolic process (GO:0046113)4.62581466
3neuron cell-cell adhesion (GO:0007158)4.55963429
4vocalization behavior (GO:0071625)4.55133502
5regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.47094030
6regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.04907606
7dendritic spine morphogenesis (GO:0060997)3.93789389
8cellular ketone body metabolic process (GO:0046950)3.86465643
9ionotropic glutamate receptor signaling pathway (GO:0035235)3.82997062
10glutamate receptor signaling pathway (GO:0007215)3.78502934
11response to pheromone (GO:0019236)3.78221369
12neuron recognition (GO:0008038)3.74748096
13G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.67704314
14layer formation in cerebral cortex (GO:0021819)3.66388483
15positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.61818302
16membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.55381518
17regulation of short-term neuronal synaptic plasticity (GO:0048172)3.54211746
18positive regulation of phosphoprotein phosphatase activity (GO:0032516)3.52071108
19regulation of glutamate receptor signaling pathway (GO:1900449)3.51592604
20membrane hyperpolarization (GO:0060081)3.49710730
21behavioral response to nicotine (GO:0035095)3.49585751
22positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.49468143
23axonal fasciculation (GO:0007413)3.48042579
24synaptic vesicle exocytosis (GO:0016079)3.47730582
25ketone body metabolic process (GO:1902224)3.33232205
26cerebellar granule cell differentiation (GO:0021707)3.29429496
27gamma-aminobutyric acid transport (GO:0015812)3.29403743
28L-phenylalanine catabolic process (GO:0006559)3.28268733
29erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.28268733
30exploration behavior (GO:0035640)3.28245430
31protein localization to synapse (GO:0035418)3.26911203
32neurotransmitter-gated ion channel clustering (GO:0072578)3.24092849
33positive regulation of synapse assembly (GO:0051965)3.23851980
34neurotransmitter secretion (GO:0007269)3.22228483
35dendrite morphogenesis (GO:0048813)3.21603178
36gamma-aminobutyric acid signaling pathway (GO:0007214)3.20871321
37regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.19908628
38startle response (GO:0001964)3.16903778
39synaptic transmission, glutamatergic (GO:0035249)3.09594966
40central nervous system projection neuron axonogenesis (GO:0021952)3.08108573
41response to histamine (GO:0034776)3.04760088
42presynaptic membrane assembly (GO:0097105)3.04430951
43neuron-neuron synaptic transmission (GO:0007270)3.00779865
44pharyngeal system development (GO:0060037)3.00556476
45lymphangiogenesis (GO:0001946)2.97597839
46regulation of secondary heart field cardioblast proliferation (GO:0003266)2.96308178
47regulation of cardioblast proliferation (GO:0003264)2.96308178
48aromatic amino acid family catabolic process (GO:0009074)2.93418636
49L-phenylalanine metabolic process (GO:0006558)2.91287278
50erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.91287278
51smooth muscle tissue development (GO:0048745)2.90496911
52regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.89756549
53synapse assembly (GO:0007416)2.88146367
54regulation of postsynaptic membrane potential (GO:0060078)2.86643492
55presynaptic membrane organization (GO:0097090)2.85132981
56sulfation (GO:0051923)2.84773241
57glutamate secretion (GO:0014047)2.82184754
58indolalkylamine catabolic process (GO:0046218)2.81545797
59tryptophan catabolic process (GO:0006569)2.81545797
60indole-containing compound catabolic process (GO:0042436)2.81545797
61artery development (GO:0060840)2.79049013
62prepulse inhibition (GO:0060134)2.78997399
63neurotransmitter transport (GO:0006836)2.78911287
64righting reflex (GO:0060013)2.78656033
65outer ear morphogenesis (GO:0042473)2.77431882
66regulation of synaptic vesicle exocytosis (GO:2000300)2.77053974
67auditory behavior (GO:0031223)2.76870658
68postsynaptic membrane organization (GO:0001941)2.76295411
69cerebellar Purkinje cell differentiation (GO:0021702)2.75035601
70negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.73867604
71neuron remodeling (GO:0016322)2.73839670
72prostate gland growth (GO:0060736)2.73363587
73transmission of nerve impulse (GO:0019226)2.71596478
74locomotory exploration behavior (GO:0035641)2.71277234
75cell migration in hindbrain (GO:0021535)2.69312799
76limb bud formation (GO:0060174)2.68536951
77neuronal action potential propagation (GO:0019227)2.68229803
78drug catabolic process (GO:0042737)2.67611946
79regulation of mesoderm development (GO:2000380)2.66872780
80regulation of respiratory system process (GO:0044065)2.65827600
81coenzyme catabolic process (GO:0009109)2.65600404
82lateral sprouting from an epithelium (GO:0060601)2.62946378
83regulation of excitatory postsynaptic membrane potential (GO:0060079)2.61879548
84response to auditory stimulus (GO:0010996)2.60480120
85glyoxylate metabolic process (GO:0046487)2.59902288
86regulation of synapse assembly (GO:0051963)2.59879580
87regulation of bile acid biosynthetic process (GO:0070857)2.59658209
88negative regulation of axon extension involved in axon guidance (GO:0048843)2.59381996
89regulation of synaptic transmission, glutamatergic (GO:0051966)2.59279076
90glutamate metabolic process (GO:0006536)2.58367126
91long-term memory (GO:0007616)2.57966240
92regulation of axon extension involved in axon guidance (GO:0048841)2.57653351
93neuronal action potential (GO:0019228)2.57388989
94membrane depolarization during action potential (GO:0086010)2.57248892
95proline transport (GO:0015824)2.56482162
96synaptic vesicle maturation (GO:0016188)2.56122711
97somite development (GO:0061053)2.55834331
98negative regulation of dendrite development (GO:2000171)2.55641982
99regulation of neurotransmitter levels (GO:0001505)2.54039626
100cell differentiation in hindbrain (GO:0021533)2.53530276
101behavioral response to cocaine (GO:0048148)2.53167924
102regulation of axon guidance (GO:1902667)2.52648868
103negative regulation of microtubule polymerization (GO:0031115)2.52080159
104negative regulation of axon guidance (GO:1902668)2.51333497
105kynurenine metabolic process (GO:0070189)2.50803594
106tryptophan metabolic process (GO:0006568)2.50762372
107peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.48879008
108exogenous drug catabolic process (GO:0042738)2.45238857
109negative regulation of synaptic transmission, GABAergic (GO:0032229)2.43546572
110synapse organization (GO:0050808)2.42696337
111positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.42496372
112positive regulation of membrane potential (GO:0045838)2.41830947
113short-chain fatty acid metabolic process (GO:0046459)2.41559003
114regulation of respiratory gaseous exchange (GO:0043576)2.41375873
115positive regulation of synapse maturation (GO:0090129)2.41178295
116triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.41132910
117membrane depolarization (GO:0051899)2.41072652
118innervation (GO:0060384)2.41026030
119action potential (GO:0001508)2.40680154
120mechanosensory behavior (GO:0007638)2.39751300
121central nervous system neuron axonogenesis (GO:0021955)2.39743903
122negative regulation of cytosolic calcium ion concentration (GO:0051481)2.39639137
123positive regulation of synaptic transmission, GABAergic (GO:0032230)2.39484035
124homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.38568684
125regulation of long-term neuronal synaptic plasticity (GO:0048169)2.38166342
126regulation of action potential (GO:0098900)2.38068341
127reflex (GO:0060004)2.37795803
128mating behavior (GO:0007617)2.37770720
129negative regulation of keratinocyte proliferation (GO:0010839)2.37604650
130adaptation of signaling pathway (GO:0023058)2.36735661
131positive regulation of glomerulus development (GO:0090193)2.35486970
132indolalkylamine metabolic process (GO:0006586)2.34367305
133magnesium ion transport (GO:0015693)2.32565184
134retinal ganglion cell axon guidance (GO:0031290)2.32083878
135calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.32009857
136negative chemotaxis (GO:0050919)2.31423104
137sympathetic nervous system development (GO:0048485)2.30641733
138negative regulation of mast cell activation (GO:0033004)2.30039503
139spinal cord development (GO:0021510)2.29196279
140positive regulation of cardiac muscle cell differentiation (GO:2000727)2.27001922
141positive regulation of action potential (GO:0045760)2.24856871
142flavonoid metabolic process (GO:0009812)2.23658439
143regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.22842823
144indole-containing compound metabolic process (GO:0042430)2.22835801
145opsonization (GO:0008228)2.20111040
146positive regulation of phosphatase activity (GO:0010922)2.19493049
147serotonin metabolic process (GO:0042428)2.19391452
148multicellular organismal signaling (GO:0035637)2.19002588
1493-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)2.13041526
150purine ribonucleoside bisphosphate metabolic process (GO:0034035)2.13041526
151regulation of feeding behavior (GO:0060259)2.11943298
152tachykinin receptor signaling pathway (GO:0007217)2.11313338
153regulation of glomerulus development (GO:0090192)2.11286343
154primary amino compound metabolic process (GO:1901160)2.10513559
155heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)2.09907038
156atrial cardiac muscle cell action potential (GO:0086014)2.09404752
157glycosphingolipid biosynthetic process (GO:0006688)2.08815372
158negative regulation of astrocyte differentiation (GO:0048712)2.08500706
159oxidative demethylation (GO:0070989)2.06866976
160regulation of hippo signaling (GO:0035330)2.06664303
161aorta morphogenesis (GO:0035909)2.04740466
162cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742)2.04602502
163cell-cell adhesion (GO:0098609)2.04372688
164cornea development in camera-type eye (GO:0061303)2.04308687
165interkinetic nuclear migration (GO:0022027)2.03882977

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.08405946
2GBX2_23144817_ChIP-Seq_PC3_Human3.49281347
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.03601906
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.63882795
5* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.61029771
6* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.56525883
7TAF15_26573619_Chip-Seq_HEK293_Human2.36307500
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.32360343
9SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.30509059
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.28817166
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.28817166
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.27343182
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.22898537
14* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.15946368
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.06708352
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.06532242
17NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.05201158
18CTBP2_25329375_ChIP-Seq_LNCAP_Human2.04513996
19* EZH2_27294783_Chip-Seq_ESCs_Mouse2.02965374
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.02461691
21AR_21572438_ChIP-Seq_LNCaP_Human1.97966787
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.97790197
23* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97134371
24REST_21632747_ChIP-Seq_MESCs_Mouse1.97114613
25PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.86609068
26CBX2_27304074_Chip-Seq_ESCs_Mouse1.85469458
27* CTBP1_25329375_ChIP-Seq_LNCAP_Human1.84108934
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.82320009
29HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.81483780
30RNF2_27304074_Chip-Seq_ESCs_Mouse1.78341751
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.75257836
32DROSHA_22980978_ChIP-Seq_HELA_Human1.75204522
33PIAS1_25552417_ChIP-Seq_VCAP_Human1.73215350
34P300_19829295_ChIP-Seq_ESCs_Human1.68610249
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.65518703
36TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.62271623
37FLI1_27457419_Chip-Seq_LIVER_Mouse1.58307917
38SMAD4_21799915_ChIP-Seq_A2780_Human1.57124976
39MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.53913015
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.53503450
41POU3F2_20337985_ChIP-ChIP_501MEL_Human1.53236938
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.51686771
43EWS_26573619_Chip-Seq_HEK293_Human1.51648232
44IGF1R_20145208_ChIP-Seq_DFB_Human1.45180243
45REST_18959480_ChIP-ChIP_MESCs_Mouse1.43905551
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.43441808
47RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.41045596
48* CDX2_19796622_ChIP-Seq_MESCs_Mouse1.40791565
49ZNF274_21170338_ChIP-Seq_K562_Hela1.40539642
50RNF2_27304074_Chip-Seq_NSC_Mouse1.38833560
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.38780339
52ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.38519122
53SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.36298267
54AR_25329375_ChIP-Seq_VCAP_Human1.36091631
55ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.34539224
56* PCGF2_27294783_Chip-Seq_ESCs_Mouse1.30071250
57VDR_22108803_ChIP-Seq_LS180_Human1.29491640
58BCAT_22108803_ChIP-Seq_LS180_Human1.28231007
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27540373
60SMAD_19615063_ChIP-ChIP_OVARY_Human1.26670224
61* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26038186
62SALL1_21062744_ChIP-ChIP_HESCs_Human1.25511221
63TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.24931934
64POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.24931934
65RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24818723
66CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.24780327
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24039801
68CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.24019907
69NRF2_20460467_ChIP-Seq_MEFs_Mouse1.23888186
70NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.23888186
71* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.23433422
72ARNT_22903824_ChIP-Seq_MCF-7_Human1.20229322
73SOX2_21211035_ChIP-Seq_LN229_Gbm1.19764139
74* SUZ12_27294783_Chip-Seq_NPCs_Mouse1.19754184
75ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19417055
76TP53_16413492_ChIP-PET_HCT116_Human1.19137239
77* STAT3_23295773_ChIP-Seq_U87_Human1.18852525
78FUS_26573619_Chip-Seq_HEK293_Human1.17546346
79* RING1B_27294783_Chip-Seq_ESCs_Mouse1.17524407
80IKZF1_21737484_ChIP-ChIP_HCT116_Human1.17020825
81P53_22127205_ChIP-Seq_FIBROBLAST_Human1.16409553
82EP300_21415370_ChIP-Seq_HL-1_Mouse1.14500702
83BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.13630903
84ER_23166858_ChIP-Seq_MCF-7_Human1.13239269
85* EZH2_27294783_Chip-Seq_NPCs_Mouse1.13078998
86AHR_22903824_ChIP-Seq_MCF-7_Human1.12069241
87* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.11613086
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11338335
89TCF4_22108803_ChIP-Seq_LS180_Human1.11082112
90SMAD4_21741376_ChIP-Seq_EPCs_Human1.10896506
91CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10796401
92* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.10423414
93* P53_22387025_ChIP-Seq_ESCs_Mouse1.09582442
94* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09479654
95KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08912359
96* CJUN_26792858_Chip-Seq_BT549_Human1.08364747
97FLI1_21867929_ChIP-Seq_TH2_Mouse1.07795979
98FOXM1_26456572_ChIP-Seq_MCF-7_Human1.07484015
99* RXR_22158963_ChIP-Seq_LIVER_Mouse1.07136551
100RUNX2_22187159_ChIP-Seq_PCA_Human1.06607356
101* NANOG_18555785_Chip-Seq_ESCs_Mouse1.05670170
102AR_19668381_ChIP-Seq_PC3_Human1.04793805
103RARB_27405468_Chip-Seq_BRAIN_Mouse1.02804439
104TCF4_23295773_ChIP-Seq_U87_Human1.02693922
105FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.02191984
106RING1B_27294783_Chip-Seq_NPCs_Mouse1.01737526
107TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01548328
108NR3C1_23031785_ChIP-Seq_PC12_Mouse1.00806912
109ERG_21242973_ChIP-ChIP_JURKAT_Human0.99706607
110* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98606845
111KDM2B_26808549_Chip-Seq_REH_Human0.97921743
112SMAD4_21741376_ChIP-Seq_HESCs_Human0.95474417
113* TP53_18474530_ChIP-ChIP_U2OS_Human0.92227011
114IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.91537558
115CBP_20019798_ChIP-Seq_JUKART_Human0.91537558
116* E2F1_18555785_Chip-Seq_ESCs_Mouse0.90743514
117LXR_22158963_ChIP-Seq_LIVER_Mouse0.90714015
118NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.89645821
119JUN_21703547_ChIP-Seq_K562_Human0.89509262
120SMAD3_21741376_ChIP-Seq_HESCs_Human0.89260170
121MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.88939664
122YAP1_20516196_ChIP-Seq_MESCs_Mouse0.88517295
123* CMYC_18555785_Chip-Seq_ESCs_Mouse0.87917574
124PRDM14_20953172_ChIP-Seq_ESCs_Human0.86990005

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern3.51365756
2MP0005423_abnormal_somatic_nervous3.39024253
3MP0005360_urolithiasis3.27001736
4MP0002139_abnormal_hepatobiliary_system3.20729619
5MP0004859_abnormal_synaptic_plasticity2.95522802
6MP0003635_abnormal_synaptic_transmissio2.93772283
7MP0004270_analgesia2.60741996
8MP0001968_abnormal_touch/_nociception2.55191796
9MP0009745_abnormal_behavioral_response2.52326029
10MP0001486_abnormal_startle_reflex2.48541611
11MP0005085_abnormal_gallbladder_physiolo2.47810034
12MP0009046_muscle_twitch2.45153532
13MP0001440_abnormal_grooming_behavior2.38471320
14MP0002063_abnormal_learning/memory/cond2.35939695
15MP0006276_abnormal_autonomic_nervous2.33490907
16MP0002572_abnormal_emotion/affect_behav2.33094056
17MP0005365_abnormal_bile_salt2.32760393
18MP0002734_abnormal_mechanical_nocicepti2.27530619
19MP0002064_seizures2.26606332
20MP0003283_abnormal_digestive_organ2.21947032
21MP0008875_abnormal_xenobiotic_pharmacok2.19815444
22MP0000778_abnormal_nervous_system2.12286066
23MP0002272_abnormal_nervous_system2.04222011
24MP0002735_abnormal_chemical_nociception2.00431665
25MP0002184_abnormal_innervation1.98580843
26MP0002736_abnormal_nociception_after1.96382309
27MP0002138_abnormal_hepatobiliary_system1.95756226
28MP0010368_abnormal_lymphatic_system1.94742987
29MP0002067_abnormal_sensory_capabilities1.89168819
30MP0005551_abnormal_eye_electrophysiolog1.86865697
31MP0005187_abnormal_penis_morphology1.82911719
32MP0001529_abnormal_vocalization1.74425496
33MP0004924_abnormal_behavior1.73686203
34MP0005386_behavior/neurological_phenoty1.73686203
35MP0001984_abnormal_olfaction1.72104327
36MP0004742_abnormal_vestibular_system1.71460927
37MP0002557_abnormal_social/conspecific_i1.65957982
38MP0000049_abnormal_middle_ear1.59458822
39MP0003119_abnormal_digestive_system1.59017856
40MP0002234_abnormal_pharynx_morphology1.57446421
41MP0003252_abnormal_bile_duct1.55307257
42MP0005275_abnormal_skin_tensile1.55305080
43MP0004043_abnormal_pH_regulation1.52525456
44MP0000383_abnormal_hair_follicle1.52197972
45MP0001501_abnormal_sleep_pattern1.50112258
46MP0002733_abnormal_thermal_nociception1.49955186
47MP0001970_abnormal_pain_threshold1.49196134
48MP0004885_abnormal_endolymph1.49004488
49MP0009780_abnormal_chondrocyte_physiolo1.43986471
50MP0004142_abnormal_muscle_tone1.43802373
51MP0001879_abnormal_lymphatic_vessel1.43640751
52MP0000534_abnormal_ureter_morphology1.39808235
53MP0003879_abnormal_hair_cell1.38569547
54MP0010386_abnormal_urinary_bladder1.38278298
55MP0008569_lethality_at_weaning1.36796154
56MP0000013_abnormal_adipose_tissue1.34012377
57MP0001502_abnormal_circadian_rhythm1.33377474
58MP0004133_heterotaxia1.31288301
59MP0000569_abnormal_digit_pigmentation1.27615943
60MP0001188_hyperpigmentation1.25641766
61MP0010329_abnormal_lipoprotein_level1.23726791
62MP0003329_amyloid_beta_deposits1.21698169
63MP0002822_catalepsy1.21134158
64MP0008872_abnormal_physiological_respon1.20182764
65MP0010678_abnormal_skin_adnexa1.20130574
66MP0009250_abnormal_appendicular_skeleto1.18533789
67MP0002882_abnormal_neuron_morphology1.17909124
68MP0005083_abnormal_biliary_tract1.17796551
69MP0000427_abnormal_hair_cycle1.14608590
70MP0009053_abnormal_anal_canal1.14561510
71MP0002066_abnormal_motor_capabilities/c1.13955651
72MP0002160_abnormal_reproductive_system1.12087479
73MP0004215_abnormal_myocardial_fiber1.11725799
74MP0005645_abnormal_hypothalamus_physiol1.10754622
75MP0005367_renal/urinary_system_phenotyp1.10585432
76MP0000516_abnormal_urinary_system1.10585432
77MP0003937_abnormal_limbs/digits/tail_de1.09206437
78MP0002102_abnormal_ear_morphology1.09108976
79MP0003868_abnormal_feces_composition1.08332357
80MP0002909_abnormal_adrenal_gland1.07790128
81MP0005646_abnormal_pituitary_gland1.06178546
82MP0003938_abnormal_ear_development1.05970033
83MP0002282_abnormal_trachea_morphology1.05262991
84MP0004019_abnormal_vitamin_homeostasis1.05184656
85MP0002837_dystrophic_cardiac_calcinosis1.04782698
86MP0005535_abnormal_body_temperature1.04309675
87MP0000955_abnormal_spinal_cord1.04105021
88MP0002751_abnormal_autonomic_nervous1.04079086
89MP0002090_abnormal_vision1.04017966
90MP0002876_abnormal_thyroid_physiology1.03874562
91MP0003890_abnormal_embryonic-extraembry1.00161505
92MP0001905_abnormal_dopamine_level0.99052063
93MP0006072_abnormal_retinal_apoptosis0.98890875
94MP0003195_calcinosis0.98027011
95MP0004811_abnormal_neuron_physiology0.96846587
96MP0002229_neurodegeneration0.96317533
97MP0005332_abnormal_amino_acid0.95703100
98MP0006292_abnormal_olfactory_placode0.95211118
99MP0000647_abnormal_sebaceous_gland0.94265350
100MP0002152_abnormal_brain_morphology0.93848672
101MP0002928_abnormal_bile_duct0.93289949
102MP0003942_abnormal_urinary_system0.92825961
103MP0002752_abnormal_somatic_nervous0.92272518
104MP0002069_abnormal_eating/drinking_beha0.90925645
105MP0003122_maternal_imprinting0.90483742
106MP0002233_abnormal_nose_morphology0.90129983
107MP0001963_abnormal_hearing_physiology0.90083876
108MP0000538_abnormal_urinary_bladder0.89795786
109MP0001756_abnormal_urination0.89627766
110MP0000230_abnormal_systemic_arterial0.86983758
111MP0005253_abnormal_eye_physiology0.86584687
112MP0000678_abnormal_parathyroid_gland0.86419067
113MP0000026_abnormal_inner_ear0.85018834
114MP0002638_abnormal_pupillary_reflex0.84844385
115MP0003011_delayed_dark_adaptation0.84817783
116MP0009379_abnormal_foot_pigmentation0.81184468
117MP0000579_abnormal_nail_morphology0.80569440
118MP0002177_abnormal_outer_ear0.80370554
119MP0005389_reproductive_system_phenotype0.80346861
120MP0005503_abnormal_tendon_morphology0.79193784
121MP0005195_abnormal_posterior_eye0.79028178
122MP0000537_abnormal_urethra_morphology0.78552775
123MP0000631_abnormal_neuroendocrine_gland0.75347185
124MP0001177_atelectasis0.74642430
125MP0001664_abnormal_digestion0.74170394
126MP0004085_abnormal_heartbeat0.73836739
127MP0001666_abnormal_nutrient_absorption0.73538342
128MP0003633_abnormal_nervous_system0.73301319
129MP0001485_abnormal_pinna_reflex0.71518834
130MP0002118_abnormal_lipid_homeostasis0.70957552
131MP0003137_abnormal_impulse_conducting0.70910426
132MP0005379_endocrine/exocrine_gland_phen0.69458887
133MP0004145_abnormal_muscle_electrophysio0.68963957
134MP0003631_nervous_system_phenotype0.68403183
135MP0001764_abnormal_homeostasis0.67549398
136MP0008004_abnormal_stomach_pH0.65872389
137MP0000604_amyloidosis0.65704511
138MP0000566_synostosis0.65278201
139MP0003690_abnormal_glial_cell0.63695835
140MP0005448_abnormal_energy_balance0.63270878
141MP0000462_abnormal_digestive_system0.62217928

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.85828933
2Focal seizures (HP:0007359)4.72567363
3Hyperventilation (HP:0002883)4.29714147
4Absence seizures (HP:0002121)4.12184607
5Stenosis of the external auditory canal (HP:0000402)3.93136903
6Morphological abnormality of the middle ear (HP:0008609)3.87811863
7Progressive cerebellar ataxia (HP:0002073)3.82404278
8Febrile seizures (HP:0002373)3.75072668
9Atonic seizures (HP:0010819)3.71378737
10Visual hallucinations (HP:0002367)3.66821068
11Dialeptic seizures (HP:0011146)3.51689688
12Epileptic encephalopathy (HP:0200134)3.39538981
13Generalized tonic-clonic seizures (HP:0002069)3.29622835
14Abnormality of the renal collecting system (HP:0004742)3.21272326
15Drooling (HP:0002307)3.11496003
16Excessive salivation (HP:0003781)3.11496003
17Broad-based gait (HP:0002136)3.11459691
18Congenital stationary night blindness (HP:0007642)3.08419051
19Myokymia (HP:0002411)3.04558007
20Polyphagia (HP:0002591)2.91337722
21Genetic anticipation (HP:0003743)2.89247429
22Lip pit (HP:0100267)2.87918582
23Limb dystonia (HP:0002451)2.86807597
24Prolonged partial thromboplastin time (HP:0003645)2.83245633
25Deep venous thrombosis (HP:0002625)2.82567752
26Intrahepatic cholestasis (HP:0001406)2.73314554
27Short hallux (HP:0010109)2.69683856
28Abnormality of aromatic amino acid family metabolism (HP:0004338)2.69620592
29Pancreatic cysts (HP:0001737)2.68652880
30Mutism (HP:0002300)2.66820221
31Abnormality of macular pigmentation (HP:0008002)2.66202252
32Status epilepticus (HP:0002133)2.58497231
33Agitation (HP:0000713)2.57182884
34Fair hair (HP:0002286)2.56524303
35Aplasia/Hypoplasia of the hallux (HP:0008362)2.55968016
36Action tremor (HP:0002345)2.54965252
37Abnormality of the proximal phalanges of the hand (HP:0009834)2.54806039
38Abnormality of glutamine family amino acid metabolism (HP:0010902)2.54752655
39Conjugated hyperbilirubinemia (HP:0002908)2.54373407
40Increased corneal curvature (HP:0100692)2.45898286
41Keratoconus (HP:0000563)2.45898286
42Abnormality of the nasal septum (HP:0000419)2.42467591
43Scanning speech (HP:0002168)2.41241132
44Central scotoma (HP:0000603)2.38646186
45Pancreatic fibrosis (HP:0100732)2.37694829
46Renal dysplasia (HP:0000110)2.36688678
47Abnormality of the renal medulla (HP:0100957)2.36207017
48Chorioretinal atrophy (HP:0000533)2.36113644
49Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)2.35439140
50True hermaphroditism (HP:0010459)2.35413785
51Hypobetalipoproteinemia (HP:0003563)2.34686515
52Aplasia/Hypoplasia of the tibia (HP:0005772)2.34406807
53Blue irides (HP:0000635)2.32322866
54Epidermoid cyst (HP:0200040)2.29579084
55Abnormal eating behavior (HP:0100738)2.29434807
56Truncal ataxia (HP:0002078)2.29297101
57Abnormality of secondary sexual hair (HP:0009888)2.29247509
58Abnormality of the axillary hair (HP:0100134)2.29247509
59Dynein arm defect of respiratory motile cilia (HP:0012255)2.28829459
60Absent/shortened dynein arms (HP:0200106)2.28829459
61Dysdiadochokinesis (HP:0002075)2.28761911
62Neurofibrillary tangles (HP:0002185)2.27764205
63Nephronophthisis (HP:0000090)2.27303325
64Abnormality of the corticospinal tract (HP:0002492)2.25260634
65Morphological abnormality of the pyramidal tract (HP:0002062)2.25189826
66Abnormality of the phalanges of the 2nd finger (HP:0009541)2.24608879
67Abnormality of the renal cortex (HP:0011035)2.23568130
68Hyperlipoproteinemia (HP:0010980)2.23154089
69Progressive inability to walk (HP:0002505)2.22460294
70Decreased circulating renin level (HP:0003351)2.20700520
71Abnormality of the middle phalanges of the toes (HP:0010183)2.20554054
72Increased circulating renin level (HP:0000848)2.20244846
73Anxiety (HP:0000739)2.20119933
74Hypothermia (HP:0002045)2.19757486
75EEG with generalized epileptiform discharges (HP:0011198)2.18991678
76Genital tract atresia (HP:0001827)2.18666233
77Poor eye contact (HP:0000817)2.16202897
78Epileptiform EEG discharges (HP:0011182)2.15934041
79Impaired social interactions (HP:0000735)2.14011513
80Abnormal social behavior (HP:0012433)2.14011513
81Xanthomatosis (HP:0000991)2.13254664
82Ketosis (HP:0001946)2.11977065
83Abnormal ciliary motility (HP:0012262)2.11870037
84Chronic hepatic failure (HP:0100626)2.11690362
85Hemiparesis (HP:0001269)2.11377098
86Short tibia (HP:0005736)2.10668673
87Congenital sensorineural hearing impairment (HP:0008527)2.09972244
88Protruding tongue (HP:0010808)2.09850124
89Abnormality of renin-angiotensin system (HP:0000847)2.09832543
90Hyperactive renin-angiotensin system (HP:0000841)2.09659092
91Gaze-evoked nystagmus (HP:0000640)2.09511542
92Hamartoma of the eye (HP:0010568)2.08472406
93Vaginal atresia (HP:0000148)2.07133484
94Decreased central vision (HP:0007663)2.06812922
95Medial flaring of the eyebrow (HP:0010747)2.06636130
96Akinesia (HP:0002304)2.06215898
97Torticollis (HP:0000473)2.05412016
98Generalized hypopigmentation of hair (HP:0011358)2.04690499
99Exotropia (HP:0000577)2.04682135
100Hyperglycinemia (HP:0002154)2.04195329
101Abnormality of salivation (HP:0100755)2.02883739
102Psychosis (HP:0000709)2.00894589
103Tubular atrophy (HP:0000092)2.00635301
104Generalized myoclonic seizures (HP:0002123)1.99508329
105Amblyopia (HP:0000646)1.97794951
106Abolished electroretinogram (ERG) (HP:0000550)1.97471816
107Hypokalemic alkalosis (HP:0001949)1.97273705
108Abnormality of monocarboxylic acid metabolism (HP:0010996)1.96062986
109Cutaneous finger syndactyly (HP:0010554)1.95265032
110Abnormality of glycine metabolism (HP:0010895)1.95105594
111Abnormality of serine family amino acid metabolism (HP:0010894)1.95105594
112Hypsarrhythmia (HP:0002521)1.94553112
113Parakeratosis (HP:0001036)1.94189274
114Ketoacidosis (HP:0001993)1.93888385
115Short 1st metacarpal (HP:0010034)1.92171003
116Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.92171003
117Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.91916969
118Hyperaldosteronism (HP:0000859)1.91752840
119Metabolic alkalosis (HP:0200114)1.91621215
120Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.91452616
121Fetal akinesia sequence (HP:0001989)1.91419703
122Goiter (HP:0000853)1.90690876
123Hyperglycinuria (HP:0003108)1.90005516
124Supranuclear gaze palsy (HP:0000605)1.89280660
125Intention tremor (HP:0002080)1.88935637
126Shawl scrotum (HP:0000049)1.88634646
127Abnormal respiratory motile cilium physiology (HP:0012261)1.88479121
128Cerebral inclusion bodies (HP:0100314)1.87245694
129Esotropia (HP:0000565)1.86904519
130Absent speech (HP:0001344)1.86835120
131Furrowed tongue (HP:0000221)1.86400245
132Molar tooth sign on MRI (HP:0002419)1.85416935
133Abnormality of midbrain morphology (HP:0002418)1.85416935
134Symphalangism affecting the phalanges of the hand (HP:0009773)1.85302789
135Abnormality of cochlea (HP:0000375)1.85035434
136Focal dystonia (HP:0004373)1.84861793
137Poor suck (HP:0002033)1.84534594
138Polydipsia (HP:0001959)1.83189146
139Abnormal drinking behavior (HP:0030082)1.83189146
140Abnormality of the phalanges of the 5th finger (HP:0004213)1.82520640
141Mixed hearing impairment (HP:0000410)1.82500166
142Polyuria (HP:0000103)1.81144801
143Preauricular pit (HP:0004467)1.79702911
144Periauricular skin pits (HP:0100277)1.79702911
145Megalencephaly (HP:0001355)1.79342649
146Congenital, generalized hypertrichosis (HP:0004540)1.79216247
147Dysmetria (HP:0001310)1.79153936
148Hypophosphatemic rickets (HP:0004912)1.79003835
149Hypokalemia (HP:0002900)1.77923902
150Craniofacial dystonia (HP:0012179)1.77750633
151Nephrogenic diabetes insipidus (HP:0009806)1.77369996
152Joint hemorrhage (HP:0005261)1.77253831
153Cupped ear (HP:0000378)1.75760178
154Hypomagnesemia (HP:0002917)1.74429303
155Pheochromocytoma (HP:0002666)1.74266582
156Down-sloping shoulders (HP:0200021)1.74155595
157Abnormality of proline metabolism (HP:0010907)1.73915980
158Hydroxyprolinuria (HP:0003080)1.73915980
159Hyperammonemia (HP:0001987)1.73883372
160Potter facies (HP:0002009)1.72927434
161Facial shape deformation (HP:0011334)1.72927434
162Hypochromic microcytic anemia (HP:0004840)1.72691997
163Inability to walk (HP:0002540)1.72500073
164Degeneration of the lateral corticospinal tracts (HP:0002314)1.71076935
165Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.71076935
166Short 4th metacarpal (HP:0010044)1.70585095
167Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.70585095
168Complement deficiency (HP:0004431)1.69913608
169Amyotrophic lateral sclerosis (HP:0007354)1.69821493
170Gait imbalance (HP:0002141)1.69610983
171Methylmalonic acidemia (HP:0002912)1.69336498

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.49232618
2MAP3K43.13896328
3NTRK22.97973748
4MAP2K72.94962033
5PNCK2.80871617
6SIK22.77104079
7CASK2.61408312
8MAPK132.50843693
9NTRK32.24603955
10MAP2K42.16215543
11MAP4K21.96436429
12TIE11.94767825
13MAP3K91.94233110
14ACVR1B1.91252091
15TNIK1.89196435
16DYRK21.76911068
17MINK11.72247934
18EPHA41.69509320
19AKT31.60361977
20PHKG21.55543486
21PHKG11.55543486
22PINK11.49496462
23WNK31.48549481
24TRIM281.46661663
25DAPK21.44988389
26PAK61.42978870
27CAMK1G1.39763287
28SIK31.39302899
29KSR11.34191386
30PKN11.31845057
31INSRR1.31547655
32LMTK21.26196496
33MAP3K121.25070756
34OXSR11.22481405
35UHMK11.21200597
36EPHB21.14883693
37NUAK11.12507298
38CDK51.12260774
39TAOK31.11120910
40ERBB31.10822878
41TGFBR11.09136775
42BCR1.05990749
43PAK31.05830339
44STK381.03531991
45CSNK1G21.01357459
46SGK2230.97460507
47SGK4940.97460507
48DYRK1A0.96495857
49EPHA30.96489129
50PRKCG0.94390302
51SIK10.92603252
52CAMK2A0.91639344
53ADRBK10.91604814
54PIK3CA0.91473200
55WNK40.89171944
56MYLK0.87431138
57GRK50.86489089
58MAPK120.85128482
59PRKCZ0.84767542
60PLK20.82624742
61SGK30.82594749
62MARK20.81482897
63STK38L0.80072860
64FRK0.79661549
65PRKCE0.78984363
66NTRK10.77942635
67FGFR20.77741519
68SGK20.77019606
69MAP3K60.76165138
70CAMKK20.75855071
71STK390.75758475
72CAMK2B0.72885493
73STK110.72845874
74MKNK20.72467706
75CSNK1G30.71992640
76BMPR1B0.71165701
77LATS20.69753285
78MUSK0.67815047
79PRKG10.67809559
80MAPK40.67185912
81GRK10.67046706
82NLK0.66734812
83GRK70.64271776
84MAP3K70.64090554
85WNK10.62755539
86STK240.62026192
87ERBB40.59767979
88CSNK1A1L0.59568330
89LATS10.56863351
90TLK10.56264719
91SGK10.55885482
92CAMK40.55378812
93CDK180.54125124
94CAMK10.53721172
95MST1R0.53231401
96ERBB20.53090434
97CDK150.52223239
98NME10.52021091
99CAMKK10.51220153
100PRKACA0.50424630
101PRKAA10.50422988
102CSNK1G10.48537401
103IRAK20.48412244
104PRKCB0.47713170
105EIF2AK30.46712782
106FLT30.46529736
107BCKDK0.46341407
108CDK140.46212989
109PTK2B0.46099317
110CAMK2D0.45054729
111KIT0.45044734
112PRKACG0.44750835
113MAP2K10.44698050
114FER0.44623055
115CDK190.44337535
116CDK30.44194358
117PRKCH0.44015789
118CSNK1A10.43752383
119OBSCN0.43547505
120CAMK2G0.43095433
121ROCK10.42977083
122CDK11A0.42734053
123FES0.42654330
124FGR0.42648411
125ROCK20.40922628
126ADRBK20.40438696
127PDGFRB0.39376679
128PRKCA0.37476688
129ZAK0.37228028
130MAPKAPK30.37005783
131CSNK1D0.35519218
132RPS6KA20.34703958
133TGFBR20.34270920
134RPS6KB10.34251754
135ABL10.34251329
136PRKAA20.33273857

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.79465440
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.13430624
3Butanoate metabolism_Homo sapiens_hsa006502.58614391
4Caffeine metabolism_Homo sapiens_hsa002322.25608847
5GABAergic synapse_Homo sapiens_hsa047272.23353248
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.13413050
7Primary bile acid biosynthesis_Homo sapiens_hsa001202.12245910
8Linoleic acid metabolism_Homo sapiens_hsa005912.10343193
9Nitrogen metabolism_Homo sapiens_hsa009101.94927617
10Glutamatergic synapse_Homo sapiens_hsa047241.89315945
11Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.87397593
12Arginine biosynthesis_Homo sapiens_hsa002201.77107047
13Morphine addiction_Homo sapiens_hsa050321.76137913
14Synaptic vesicle cycle_Homo sapiens_hsa047211.74291253
15Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.72456644
16Taste transduction_Homo sapiens_hsa047421.70326686
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.64470691
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.62195221
19Circadian entrainment_Homo sapiens_hsa047131.57334254
20Tryptophan metabolism_Homo sapiens_hsa003801.54098669
21Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.52646805
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.44028047
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.43571531
24Bile secretion_Homo sapiens_hsa049761.39615210
25Serotonergic synapse_Homo sapiens_hsa047261.38565517
26Dorso-ventral axis formation_Homo sapiens_hsa043201.34276713
27Fatty acid degradation_Homo sapiens_hsa000711.31847306
28Olfactory transduction_Homo sapiens_hsa047401.24273491
29Propanoate metabolism_Homo sapiens_hsa006401.24099766
30Amphetamine addiction_Homo sapiens_hsa050311.19470619
31Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.19246960
32Salivary secretion_Homo sapiens_hsa049701.19107008
33Dopaminergic synapse_Homo sapiens_hsa047281.17645180
34Insulin secretion_Homo sapiens_hsa049111.17576623
35Fatty acid metabolism_Homo sapiens_hsa012121.17431676
36Steroid hormone biosynthesis_Homo sapiens_hsa001401.17392196
37Long-term depression_Homo sapiens_hsa047301.15970899
38Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.15903213
39Complement and coagulation cascades_Homo sapiens_hsa046101.14984997
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.14833548
41ECM-receptor interaction_Homo sapiens_hsa045121.13956468
42Ether lipid metabolism_Homo sapiens_hsa005651.13539660
43Renin secretion_Homo sapiens_hsa049241.13349321
44Long-term potentiation_Homo sapiens_hsa047201.12377156
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11993490
46Cocaine addiction_Homo sapiens_hsa050301.11069696
47Cardiac muscle contraction_Homo sapiens_hsa042601.10693840
48Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.10139985
49PPAR signaling pathway_Homo sapiens_hsa033201.09321602
50Cholinergic synapse_Homo sapiens_hsa047251.09309062
51Fatty acid elongation_Homo sapiens_hsa000621.09034426
52Axon guidance_Homo sapiens_hsa043601.07939449
53Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.06692156
54Phototransduction_Homo sapiens_hsa047441.06646507
55Oxidative phosphorylation_Homo sapiens_hsa001901.06467377
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.05764932
57Steroid biosynthesis_Homo sapiens_hsa001001.05228908
58Peroxisome_Homo sapiens_hsa041461.04981746
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.04564200
60Aldosterone synthesis and secretion_Homo sapiens_hsa049251.02558587
61Retinol metabolism_Homo sapiens_hsa008301.00457580
62TGF-beta signaling pathway_Homo sapiens_hsa043500.98796224
63Gastric acid secretion_Homo sapiens_hsa049710.98300820
64Tyrosine metabolism_Homo sapiens_hsa003500.96436295
65Alzheimers disease_Homo sapiens_hsa050100.93648606
66beta-Alanine metabolism_Homo sapiens_hsa004100.91884645
67Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.91468876
68Sulfur metabolism_Homo sapiens_hsa009200.89867313
69Chemical carcinogenesis_Homo sapiens_hsa052040.87606549
70Hedgehog signaling pathway_Homo sapiens_hsa043400.87418898
71Arachidonic acid metabolism_Homo sapiens_hsa005900.87337571
72Pyruvate metabolism_Homo sapiens_hsa006200.87301925
73Protein digestion and absorption_Homo sapiens_hsa049740.83579317
74Histidine metabolism_Homo sapiens_hsa003400.83553198
75Calcium signaling pathway_Homo sapiens_hsa040200.83239520
76Protein export_Homo sapiens_hsa030600.82778141
77Phenylalanine metabolism_Homo sapiens_hsa003600.78575817
78Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.78240247
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.77154842
80Parkinsons disease_Homo sapiens_hsa050120.73501839
81Oxytocin signaling pathway_Homo sapiens_hsa049210.73400310
82ABC transporters_Homo sapiens_hsa020100.72786583
83Hippo signaling pathway_Homo sapiens_hsa043900.72668659
84Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.72054363
85Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.71963301
86Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.70931523
87Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.70254494
88Collecting duct acid secretion_Homo sapiens_hsa049660.69700028
89Selenocompound metabolism_Homo sapiens_hsa004500.69143096
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.68896385
91Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.68431646
92Gap junction_Homo sapiens_hsa045400.68023223
93Dilated cardiomyopathy_Homo sapiens_hsa054140.66991703
94Basal cell carcinoma_Homo sapiens_hsa052170.64732318
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.63078716
96Fat digestion and absorption_Homo sapiens_hsa049750.62005678
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.60757863
98Pancreatic secretion_Homo sapiens_hsa049720.60359661
99Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.60356003
100Type II diabetes mellitus_Homo sapiens_hsa049300.60090943
101cAMP signaling pathway_Homo sapiens_hsa040240.59084227
102Ras signaling pathway_Homo sapiens_hsa040140.58761302
103Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.58686809
104GnRH signaling pathway_Homo sapiens_hsa049120.57699489
105Circadian rhythm_Homo sapiens_hsa047100.57575569
106Mineral absorption_Homo sapiens_hsa049780.57176297
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.52907697
108Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.51590229
109Vitamin digestion and absorption_Homo sapiens_hsa049770.51059598
110Drug metabolism - other enzymes_Homo sapiens_hsa009830.50198065
111Starch and sucrose metabolism_Homo sapiens_hsa005000.50052219
112ErbB signaling pathway_Homo sapiens_hsa040120.49495787
1132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.48955508
114Maturity onset diabetes of the young_Homo sapiens_hsa049500.48803524
115Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48736755
116Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.48341888
117Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.46780249
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45972622
119Fatty acid biosynthesis_Homo sapiens_hsa000610.44078347
120Staphylococcus aureus infection_Homo sapiens_hsa051500.42517340
121Ovarian steroidogenesis_Homo sapiens_hsa049130.41127805
122Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.40699717
123Glycerolipid metabolism_Homo sapiens_hsa005610.40215654
124Vascular smooth muscle contraction_Homo sapiens_hsa042700.39908254
125Huntingtons disease_Homo sapiens_hsa050160.36337029
126Lysine degradation_Homo sapiens_hsa003100.36202691
127African trypanosomiasis_Homo sapiens_hsa051430.35847325

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