Rank | Gene Set | Z-score |
---|---|---|
1 | pyrimidine nucleobase catabolic process (GO:0006208) | 5.59872960 |
2 | nucleobase catabolic process (GO:0046113) | 4.62581466 |
3 | neuron cell-cell adhesion (GO:0007158) | 4.55963429 |
4 | vocalization behavior (GO:0071625) | 4.55133502 |
5 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 4.47094030 |
6 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 4.04907606 |
7 | dendritic spine morphogenesis (GO:0060997) | 3.93789389 |
8 | cellular ketone body metabolic process (GO:0046950) | 3.86465643 |
9 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.82997062 |
10 | glutamate receptor signaling pathway (GO:0007215) | 3.78502934 |
11 | response to pheromone (GO:0019236) | 3.78221369 |
12 | neuron recognition (GO:0008038) | 3.74748096 |
13 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.67704314 |
14 | layer formation in cerebral cortex (GO:0021819) | 3.66388483 |
15 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.61818302 |
16 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.55381518 |
17 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.54211746 |
18 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.52071108 |
19 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.51592604 |
20 | membrane hyperpolarization (GO:0060081) | 3.49710730 |
21 | behavioral response to nicotine (GO:0035095) | 3.49585751 |
22 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.49468143 |
23 | axonal fasciculation (GO:0007413) | 3.48042579 |
24 | synaptic vesicle exocytosis (GO:0016079) | 3.47730582 |
25 | ketone body metabolic process (GO:1902224) | 3.33232205 |
26 | cerebellar granule cell differentiation (GO:0021707) | 3.29429496 |
27 | gamma-aminobutyric acid transport (GO:0015812) | 3.29403743 |
28 | L-phenylalanine catabolic process (GO:0006559) | 3.28268733 |
29 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.28268733 |
30 | exploration behavior (GO:0035640) | 3.28245430 |
31 | protein localization to synapse (GO:0035418) | 3.26911203 |
32 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.24092849 |
33 | positive regulation of synapse assembly (GO:0051965) | 3.23851980 |
34 | neurotransmitter secretion (GO:0007269) | 3.22228483 |
35 | dendrite morphogenesis (GO:0048813) | 3.21603178 |
36 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.20871321 |
37 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.19908628 |
38 | startle response (GO:0001964) | 3.16903778 |
39 | synaptic transmission, glutamatergic (GO:0035249) | 3.09594966 |
40 | central nervous system projection neuron axonogenesis (GO:0021952) | 3.08108573 |
41 | response to histamine (GO:0034776) | 3.04760088 |
42 | presynaptic membrane assembly (GO:0097105) | 3.04430951 |
43 | neuron-neuron synaptic transmission (GO:0007270) | 3.00779865 |
44 | pharyngeal system development (GO:0060037) | 3.00556476 |
45 | lymphangiogenesis (GO:0001946) | 2.97597839 |
46 | regulation of secondary heart field cardioblast proliferation (GO:0003266) | 2.96308178 |
47 | regulation of cardioblast proliferation (GO:0003264) | 2.96308178 |
48 | aromatic amino acid family catabolic process (GO:0009074) | 2.93418636 |
49 | L-phenylalanine metabolic process (GO:0006558) | 2.91287278 |
50 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 2.91287278 |
51 | smooth muscle tissue development (GO:0048745) | 2.90496911 |
52 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.89756549 |
53 | synapse assembly (GO:0007416) | 2.88146367 |
54 | regulation of postsynaptic membrane potential (GO:0060078) | 2.86643492 |
55 | presynaptic membrane organization (GO:0097090) | 2.85132981 |
56 | sulfation (GO:0051923) | 2.84773241 |
57 | glutamate secretion (GO:0014047) | 2.82184754 |
58 | indolalkylamine catabolic process (GO:0046218) | 2.81545797 |
59 | tryptophan catabolic process (GO:0006569) | 2.81545797 |
60 | indole-containing compound catabolic process (GO:0042436) | 2.81545797 |
61 | artery development (GO:0060840) | 2.79049013 |
62 | prepulse inhibition (GO:0060134) | 2.78997399 |
63 | neurotransmitter transport (GO:0006836) | 2.78911287 |
64 | righting reflex (GO:0060013) | 2.78656033 |
65 | outer ear morphogenesis (GO:0042473) | 2.77431882 |
66 | regulation of synaptic vesicle exocytosis (GO:2000300) | 2.77053974 |
67 | auditory behavior (GO:0031223) | 2.76870658 |
68 | postsynaptic membrane organization (GO:0001941) | 2.76295411 |
69 | cerebellar Purkinje cell differentiation (GO:0021702) | 2.75035601 |
70 | negative regulation of synaptic transmission, glutamatergic (GO:0051967) | 2.73867604 |
71 | neuron remodeling (GO:0016322) | 2.73839670 |
72 | prostate gland growth (GO:0060736) | 2.73363587 |
73 | transmission of nerve impulse (GO:0019226) | 2.71596478 |
74 | locomotory exploration behavior (GO:0035641) | 2.71277234 |
75 | cell migration in hindbrain (GO:0021535) | 2.69312799 |
76 | limb bud formation (GO:0060174) | 2.68536951 |
77 | neuronal action potential propagation (GO:0019227) | 2.68229803 |
78 | drug catabolic process (GO:0042737) | 2.67611946 |
79 | regulation of mesoderm development (GO:2000380) | 2.66872780 |
80 | regulation of respiratory system process (GO:0044065) | 2.65827600 |
81 | coenzyme catabolic process (GO:0009109) | 2.65600404 |
82 | lateral sprouting from an epithelium (GO:0060601) | 2.62946378 |
83 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 2.61879548 |
84 | response to auditory stimulus (GO:0010996) | 2.60480120 |
85 | glyoxylate metabolic process (GO:0046487) | 2.59902288 |
86 | regulation of synapse assembly (GO:0051963) | 2.59879580 |
87 | regulation of bile acid biosynthetic process (GO:0070857) | 2.59658209 |
88 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.59381996 |
89 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 2.59279076 |
90 | glutamate metabolic process (GO:0006536) | 2.58367126 |
91 | long-term memory (GO:0007616) | 2.57966240 |
92 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.57653351 |
93 | neuronal action potential (GO:0019228) | 2.57388989 |
94 | membrane depolarization during action potential (GO:0086010) | 2.57248892 |
95 | proline transport (GO:0015824) | 2.56482162 |
96 | synaptic vesicle maturation (GO:0016188) | 2.56122711 |
97 | somite development (GO:0061053) | 2.55834331 |
98 | negative regulation of dendrite development (GO:2000171) | 2.55641982 |
99 | regulation of neurotransmitter levels (GO:0001505) | 2.54039626 |
100 | cell differentiation in hindbrain (GO:0021533) | 2.53530276 |
101 | behavioral response to cocaine (GO:0048148) | 2.53167924 |
102 | regulation of axon guidance (GO:1902667) | 2.52648868 |
103 | negative regulation of microtubule polymerization (GO:0031115) | 2.52080159 |
104 | negative regulation of axon guidance (GO:1902668) | 2.51333497 |
105 | kynurenine metabolic process (GO:0070189) | 2.50803594 |
106 | tryptophan metabolic process (GO:0006568) | 2.50762372 |
107 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.48879008 |
108 | exogenous drug catabolic process (GO:0042738) | 2.45238857 |
109 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.43546572 |
110 | synapse organization (GO:0050808) | 2.42696337 |
111 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 2.42496372 |
112 | positive regulation of membrane potential (GO:0045838) | 2.41830947 |
113 | short-chain fatty acid metabolic process (GO:0046459) | 2.41559003 |
114 | regulation of respiratory gaseous exchange (GO:0043576) | 2.41375873 |
115 | positive regulation of synapse maturation (GO:0090129) | 2.41178295 |
116 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 2.41132910 |
117 | membrane depolarization (GO:0051899) | 2.41072652 |
118 | innervation (GO:0060384) | 2.41026030 |
119 | action potential (GO:0001508) | 2.40680154 |
120 | mechanosensory behavior (GO:0007638) | 2.39751300 |
121 | central nervous system neuron axonogenesis (GO:0021955) | 2.39743903 |
122 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.39639137 |
123 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.39484035 |
124 | homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) | 2.38568684 |
125 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 2.38166342 |
126 | regulation of action potential (GO:0098900) | 2.38068341 |
127 | reflex (GO:0060004) | 2.37795803 |
128 | mating behavior (GO:0007617) | 2.37770720 |
129 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.37604650 |
130 | adaptation of signaling pathway (GO:0023058) | 2.36735661 |
131 | positive regulation of glomerulus development (GO:0090193) | 2.35486970 |
132 | indolalkylamine metabolic process (GO:0006586) | 2.34367305 |
133 | magnesium ion transport (GO:0015693) | 2.32565184 |
134 | retinal ganglion cell axon guidance (GO:0031290) | 2.32083878 |
135 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) | 2.32009857 |
136 | negative chemotaxis (GO:0050919) | 2.31423104 |
137 | sympathetic nervous system development (GO:0048485) | 2.30641733 |
138 | negative regulation of mast cell activation (GO:0033004) | 2.30039503 |
139 | spinal cord development (GO:0021510) | 2.29196279 |
140 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.27001922 |
141 | positive regulation of action potential (GO:0045760) | 2.24856871 |
142 | flavonoid metabolic process (GO:0009812) | 2.23658439 |
143 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.22842823 |
144 | indole-containing compound metabolic process (GO:0042430) | 2.22835801 |
145 | opsonization (GO:0008228) | 2.20111040 |
146 | positive regulation of phosphatase activity (GO:0010922) | 2.19493049 |
147 | serotonin metabolic process (GO:0042428) | 2.19391452 |
148 | multicellular organismal signaling (GO:0035637) | 2.19002588 |
149 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.13041526 |
150 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.13041526 |
151 | regulation of feeding behavior (GO:0060259) | 2.11943298 |
152 | tachykinin receptor signaling pathway (GO:0007217) | 2.11313338 |
153 | regulation of glomerulus development (GO:0090192) | 2.11286343 |
154 | primary amino compound metabolic process (GO:1901160) | 2.10513559 |
155 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157) | 2.09907038 |
156 | atrial cardiac muscle cell action potential (GO:0086014) | 2.09404752 |
157 | glycosphingolipid biosynthetic process (GO:0006688) | 2.08815372 |
158 | negative regulation of astrocyte differentiation (GO:0048712) | 2.08500706 |
159 | oxidative demethylation (GO:0070989) | 2.06866976 |
160 | regulation of hippo signaling (GO:0035330) | 2.06664303 |
161 | aorta morphogenesis (GO:0035909) | 2.04740466 |
162 | cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) | 2.04602502 |
163 | cell-cell adhesion (GO:0098609) | 2.04372688 |
164 | cornea development in camera-type eye (GO:0061303) | 2.04308687 |
165 | interkinetic nuclear migration (GO:0022027) | 2.03882977 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.08405946 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.49281347 |
3 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.03601906 |
4 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.63882795 |
5 | * SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.61029771 |
6 | * SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.56525883 |
7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.36307500 |
8 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.32360343 |
9 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.30509059 |
10 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.28817166 |
11 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.28817166 |
12 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.27343182 |
13 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.22898537 |
14 | * SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.15946368 |
15 | * MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.06708352 |
16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.06532242 |
17 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.05201158 |
18 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.04513996 |
19 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.02965374 |
20 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.02461691 |
21 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.97966787 |
22 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.97790197 |
23 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.97134371 |
24 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.97114613 |
25 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.86609068 |
26 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.85469458 |
27 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.84108934 |
28 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.82320009 |
29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.81483780 |
30 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.78341751 |
31 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.75257836 |
32 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.75204522 |
33 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.73215350 |
34 | P300_19829295_ChIP-Seq_ESCs_Human | 1.68610249 |
35 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.65518703 |
36 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.62271623 |
37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58307917 |
38 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.57124976 |
39 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.53913015 |
40 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.53503450 |
41 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.53236938 |
42 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.51686771 |
43 | EWS_26573619_Chip-Seq_HEK293_Human | 1.51648232 |
44 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.45180243 |
45 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.43905551 |
46 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.43441808 |
47 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.41045596 |
48 | * CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.40791565 |
49 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.40539642 |
50 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.38833560 |
51 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.38780339 |
52 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.38519122 |
53 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.36298267 |
54 | AR_25329375_ChIP-Seq_VCAP_Human | 1.36091631 |
55 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.34539224 |
56 | * PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.30071250 |
57 | VDR_22108803_ChIP-Seq_LS180_Human | 1.29491640 |
58 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.28231007 |
59 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.27540373 |
60 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.26670224 |
61 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.26038186 |
62 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.25511221 |
63 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.24931934 |
64 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.24931934 |
65 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.24818723 |
66 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.24780327 |
67 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.24039801 |
68 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.24019907 |
69 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.23888186 |
70 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.23888186 |
71 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.23433422 |
72 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.20229322 |
73 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.19764139 |
74 | * SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.19754184 |
75 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.19417055 |
76 | TP53_16413492_ChIP-PET_HCT116_Human | 1.19137239 |
77 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.18852525 |
78 | FUS_26573619_Chip-Seq_HEK293_Human | 1.17546346 |
79 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.17524407 |
80 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.17020825 |
81 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.16409553 |
82 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.14500702 |
83 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.13630903 |
84 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.13239269 |
85 | * EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.13078998 |
86 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.12069241 |
87 | * TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.11613086 |
88 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.11338335 |
89 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.11082112 |
90 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.10896506 |
91 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10796401 |
92 | * TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.10423414 |
93 | * P53_22387025_ChIP-Seq_ESCs_Mouse | 1.09582442 |
94 | * TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.09479654 |
95 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.08912359 |
96 | * CJUN_26792858_Chip-Seq_BT549_Human | 1.08364747 |
97 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.07795979 |
98 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.07484015 |
99 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.07136551 |
100 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.06607356 |
101 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.05670170 |
102 | AR_19668381_ChIP-Seq_PC3_Human | 1.04793805 |
103 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.02804439 |
104 | TCF4_23295773_ChIP-Seq_U87_Human | 1.02693922 |
105 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.02191984 |
106 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.01737526 |
107 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01548328 |
108 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.00806912 |
109 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.99706607 |
110 | * EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.98606845 |
111 | KDM2B_26808549_Chip-Seq_REH_Human | 0.97921743 |
112 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95474417 |
113 | * TP53_18474530_ChIP-ChIP_U2OS_Human | 0.92227011 |
114 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91537558 |
115 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91537558 |
116 | * E2F1_18555785_Chip-Seq_ESCs_Mouse | 0.90743514 |
117 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.90714015 |
118 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.89645821 |
119 | JUN_21703547_ChIP-Seq_K562_Human | 0.89509262 |
120 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.89260170 |
121 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.88939664 |
122 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.88517295 |
123 | * CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.87917574 |
124 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.86990005 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 3.51365756 |
2 | MP0005423_abnormal_somatic_nervous | 3.39024253 |
3 | MP0005360_urolithiasis | 3.27001736 |
4 | MP0002139_abnormal_hepatobiliary_system | 3.20729619 |
5 | MP0004859_abnormal_synaptic_plasticity | 2.95522802 |
6 | MP0003635_abnormal_synaptic_transmissio | 2.93772283 |
7 | MP0004270_analgesia | 2.60741996 |
8 | MP0001968_abnormal_touch/_nociception | 2.55191796 |
9 | MP0009745_abnormal_behavioral_response | 2.52326029 |
10 | MP0001486_abnormal_startle_reflex | 2.48541611 |
11 | MP0005085_abnormal_gallbladder_physiolo | 2.47810034 |
12 | MP0009046_muscle_twitch | 2.45153532 |
13 | MP0001440_abnormal_grooming_behavior | 2.38471320 |
14 | MP0002063_abnormal_learning/memory/cond | 2.35939695 |
15 | MP0006276_abnormal_autonomic_nervous | 2.33490907 |
16 | MP0002572_abnormal_emotion/affect_behav | 2.33094056 |
17 | MP0005365_abnormal_bile_salt | 2.32760393 |
18 | MP0002734_abnormal_mechanical_nocicepti | 2.27530619 |
19 | MP0002064_seizures | 2.26606332 |
20 | MP0003283_abnormal_digestive_organ | 2.21947032 |
21 | MP0008875_abnormal_xenobiotic_pharmacok | 2.19815444 |
22 | MP0000778_abnormal_nervous_system | 2.12286066 |
23 | MP0002272_abnormal_nervous_system | 2.04222011 |
24 | MP0002735_abnormal_chemical_nociception | 2.00431665 |
25 | MP0002184_abnormal_innervation | 1.98580843 |
26 | MP0002736_abnormal_nociception_after | 1.96382309 |
27 | MP0002138_abnormal_hepatobiliary_system | 1.95756226 |
28 | MP0010368_abnormal_lymphatic_system | 1.94742987 |
29 | MP0002067_abnormal_sensory_capabilities | 1.89168819 |
30 | MP0005551_abnormal_eye_electrophysiolog | 1.86865697 |
31 | MP0005187_abnormal_penis_morphology | 1.82911719 |
32 | MP0001529_abnormal_vocalization | 1.74425496 |
33 | MP0004924_abnormal_behavior | 1.73686203 |
34 | MP0005386_behavior/neurological_phenoty | 1.73686203 |
35 | MP0001984_abnormal_olfaction | 1.72104327 |
36 | MP0004742_abnormal_vestibular_system | 1.71460927 |
37 | MP0002557_abnormal_social/conspecific_i | 1.65957982 |
38 | MP0000049_abnormal_middle_ear | 1.59458822 |
39 | MP0003119_abnormal_digestive_system | 1.59017856 |
40 | MP0002234_abnormal_pharynx_morphology | 1.57446421 |
41 | MP0003252_abnormal_bile_duct | 1.55307257 |
42 | MP0005275_abnormal_skin_tensile | 1.55305080 |
43 | MP0004043_abnormal_pH_regulation | 1.52525456 |
44 | MP0000383_abnormal_hair_follicle | 1.52197972 |
45 | MP0001501_abnormal_sleep_pattern | 1.50112258 |
46 | MP0002733_abnormal_thermal_nociception | 1.49955186 |
47 | MP0001970_abnormal_pain_threshold | 1.49196134 |
48 | MP0004885_abnormal_endolymph | 1.49004488 |
49 | MP0009780_abnormal_chondrocyte_physiolo | 1.43986471 |
50 | MP0004142_abnormal_muscle_tone | 1.43802373 |
51 | MP0001879_abnormal_lymphatic_vessel | 1.43640751 |
52 | MP0000534_abnormal_ureter_morphology | 1.39808235 |
53 | MP0003879_abnormal_hair_cell | 1.38569547 |
54 | MP0010386_abnormal_urinary_bladder | 1.38278298 |
55 | MP0008569_lethality_at_weaning | 1.36796154 |
56 | MP0000013_abnormal_adipose_tissue | 1.34012377 |
57 | MP0001502_abnormal_circadian_rhythm | 1.33377474 |
58 | MP0004133_heterotaxia | 1.31288301 |
59 | MP0000569_abnormal_digit_pigmentation | 1.27615943 |
60 | MP0001188_hyperpigmentation | 1.25641766 |
61 | MP0010329_abnormal_lipoprotein_level | 1.23726791 |
62 | MP0003329_amyloid_beta_deposits | 1.21698169 |
63 | MP0002822_catalepsy | 1.21134158 |
64 | MP0008872_abnormal_physiological_respon | 1.20182764 |
65 | MP0010678_abnormal_skin_adnexa | 1.20130574 |
66 | MP0009250_abnormal_appendicular_skeleto | 1.18533789 |
67 | MP0002882_abnormal_neuron_morphology | 1.17909124 |
68 | MP0005083_abnormal_biliary_tract | 1.17796551 |
69 | MP0000427_abnormal_hair_cycle | 1.14608590 |
70 | MP0009053_abnormal_anal_canal | 1.14561510 |
71 | MP0002066_abnormal_motor_capabilities/c | 1.13955651 |
72 | MP0002160_abnormal_reproductive_system | 1.12087479 |
73 | MP0004215_abnormal_myocardial_fiber | 1.11725799 |
74 | MP0005645_abnormal_hypothalamus_physiol | 1.10754622 |
75 | MP0005367_renal/urinary_system_phenotyp | 1.10585432 |
76 | MP0000516_abnormal_urinary_system | 1.10585432 |
77 | MP0003937_abnormal_limbs/digits/tail_de | 1.09206437 |
78 | MP0002102_abnormal_ear_morphology | 1.09108976 |
79 | MP0003868_abnormal_feces_composition | 1.08332357 |
80 | MP0002909_abnormal_adrenal_gland | 1.07790128 |
81 | MP0005646_abnormal_pituitary_gland | 1.06178546 |
82 | MP0003938_abnormal_ear_development | 1.05970033 |
83 | MP0002282_abnormal_trachea_morphology | 1.05262991 |
84 | MP0004019_abnormal_vitamin_homeostasis | 1.05184656 |
85 | MP0002837_dystrophic_cardiac_calcinosis | 1.04782698 |
86 | MP0005535_abnormal_body_temperature | 1.04309675 |
87 | MP0000955_abnormal_spinal_cord | 1.04105021 |
88 | MP0002751_abnormal_autonomic_nervous | 1.04079086 |
89 | MP0002090_abnormal_vision | 1.04017966 |
90 | MP0002876_abnormal_thyroid_physiology | 1.03874562 |
91 | MP0003890_abnormal_embryonic-extraembry | 1.00161505 |
92 | MP0001905_abnormal_dopamine_level | 0.99052063 |
93 | MP0006072_abnormal_retinal_apoptosis | 0.98890875 |
94 | MP0003195_calcinosis | 0.98027011 |
95 | MP0004811_abnormal_neuron_physiology | 0.96846587 |
96 | MP0002229_neurodegeneration | 0.96317533 |
97 | MP0005332_abnormal_amino_acid | 0.95703100 |
98 | MP0006292_abnormal_olfactory_placode | 0.95211118 |
99 | MP0000647_abnormal_sebaceous_gland | 0.94265350 |
100 | MP0002152_abnormal_brain_morphology | 0.93848672 |
101 | MP0002928_abnormal_bile_duct | 0.93289949 |
102 | MP0003942_abnormal_urinary_system | 0.92825961 |
103 | MP0002752_abnormal_somatic_nervous | 0.92272518 |
104 | MP0002069_abnormal_eating/drinking_beha | 0.90925645 |
105 | MP0003122_maternal_imprinting | 0.90483742 |
106 | MP0002233_abnormal_nose_morphology | 0.90129983 |
107 | MP0001963_abnormal_hearing_physiology | 0.90083876 |
108 | MP0000538_abnormal_urinary_bladder | 0.89795786 |
109 | MP0001756_abnormal_urination | 0.89627766 |
110 | MP0000230_abnormal_systemic_arterial | 0.86983758 |
111 | MP0005253_abnormal_eye_physiology | 0.86584687 |
112 | MP0000678_abnormal_parathyroid_gland | 0.86419067 |
113 | MP0000026_abnormal_inner_ear | 0.85018834 |
114 | MP0002638_abnormal_pupillary_reflex | 0.84844385 |
115 | MP0003011_delayed_dark_adaptation | 0.84817783 |
116 | MP0009379_abnormal_foot_pigmentation | 0.81184468 |
117 | MP0000579_abnormal_nail_morphology | 0.80569440 |
118 | MP0002177_abnormal_outer_ear | 0.80370554 |
119 | MP0005389_reproductive_system_phenotype | 0.80346861 |
120 | MP0005503_abnormal_tendon_morphology | 0.79193784 |
121 | MP0005195_abnormal_posterior_eye | 0.79028178 |
122 | MP0000537_abnormal_urethra_morphology | 0.78552775 |
123 | MP0000631_abnormal_neuroendocrine_gland | 0.75347185 |
124 | MP0001177_atelectasis | 0.74642430 |
125 | MP0001664_abnormal_digestion | 0.74170394 |
126 | MP0004085_abnormal_heartbeat | 0.73836739 |
127 | MP0001666_abnormal_nutrient_absorption | 0.73538342 |
128 | MP0003633_abnormal_nervous_system | 0.73301319 |
129 | MP0001485_abnormal_pinna_reflex | 0.71518834 |
130 | MP0002118_abnormal_lipid_homeostasis | 0.70957552 |
131 | MP0003137_abnormal_impulse_conducting | 0.70910426 |
132 | MP0005379_endocrine/exocrine_gland_phen | 0.69458887 |
133 | MP0004145_abnormal_muscle_electrophysio | 0.68963957 |
134 | MP0003631_nervous_system_phenotype | 0.68403183 |
135 | MP0001764_abnormal_homeostasis | 0.67549398 |
136 | MP0008004_abnormal_stomach_pH | 0.65872389 |
137 | MP0000604_amyloidosis | 0.65704511 |
138 | MP0000566_synostosis | 0.65278201 |
139 | MP0003690_abnormal_glial_cell | 0.63695835 |
140 | MP0005448_abnormal_energy_balance | 0.63270878 |
141 | MP0000462_abnormal_digestive_system | 0.62217928 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 4.85828933 |
2 | Focal seizures (HP:0007359) | 4.72567363 |
3 | Hyperventilation (HP:0002883) | 4.29714147 |
4 | Absence seizures (HP:0002121) | 4.12184607 |
5 | Stenosis of the external auditory canal (HP:0000402) | 3.93136903 |
6 | Morphological abnormality of the middle ear (HP:0008609) | 3.87811863 |
7 | Progressive cerebellar ataxia (HP:0002073) | 3.82404278 |
8 | Febrile seizures (HP:0002373) | 3.75072668 |
9 | Atonic seizures (HP:0010819) | 3.71378737 |
10 | Visual hallucinations (HP:0002367) | 3.66821068 |
11 | Dialeptic seizures (HP:0011146) | 3.51689688 |
12 | Epileptic encephalopathy (HP:0200134) | 3.39538981 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.29622835 |
14 | Abnormality of the renal collecting system (HP:0004742) | 3.21272326 |
15 | Drooling (HP:0002307) | 3.11496003 |
16 | Excessive salivation (HP:0003781) | 3.11496003 |
17 | Broad-based gait (HP:0002136) | 3.11459691 |
18 | Congenital stationary night blindness (HP:0007642) | 3.08419051 |
19 | Myokymia (HP:0002411) | 3.04558007 |
20 | Polyphagia (HP:0002591) | 2.91337722 |
21 | Genetic anticipation (HP:0003743) | 2.89247429 |
22 | Lip pit (HP:0100267) | 2.87918582 |
23 | Limb dystonia (HP:0002451) | 2.86807597 |
24 | Prolonged partial thromboplastin time (HP:0003645) | 2.83245633 |
25 | Deep venous thrombosis (HP:0002625) | 2.82567752 |
26 | Intrahepatic cholestasis (HP:0001406) | 2.73314554 |
27 | Short hallux (HP:0010109) | 2.69683856 |
28 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 2.69620592 |
29 | Pancreatic cysts (HP:0001737) | 2.68652880 |
30 | Mutism (HP:0002300) | 2.66820221 |
31 | Abnormality of macular pigmentation (HP:0008002) | 2.66202252 |
32 | Status epilepticus (HP:0002133) | 2.58497231 |
33 | Agitation (HP:0000713) | 2.57182884 |
34 | Fair hair (HP:0002286) | 2.56524303 |
35 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.55968016 |
36 | Action tremor (HP:0002345) | 2.54965252 |
37 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.54806039 |
38 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.54752655 |
39 | Conjugated hyperbilirubinemia (HP:0002908) | 2.54373407 |
40 | Increased corneal curvature (HP:0100692) | 2.45898286 |
41 | Keratoconus (HP:0000563) | 2.45898286 |
42 | Abnormality of the nasal septum (HP:0000419) | 2.42467591 |
43 | Scanning speech (HP:0002168) | 2.41241132 |
44 | Central scotoma (HP:0000603) | 2.38646186 |
45 | Pancreatic fibrosis (HP:0100732) | 2.37694829 |
46 | Renal dysplasia (HP:0000110) | 2.36688678 |
47 | Abnormality of the renal medulla (HP:0100957) | 2.36207017 |
48 | Chorioretinal atrophy (HP:0000533) | 2.36113644 |
49 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.35439140 |
50 | True hermaphroditism (HP:0010459) | 2.35413785 |
51 | Hypobetalipoproteinemia (HP:0003563) | 2.34686515 |
52 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.34406807 |
53 | Blue irides (HP:0000635) | 2.32322866 |
54 | Epidermoid cyst (HP:0200040) | 2.29579084 |
55 | Abnormal eating behavior (HP:0100738) | 2.29434807 |
56 | Truncal ataxia (HP:0002078) | 2.29297101 |
57 | Abnormality of secondary sexual hair (HP:0009888) | 2.29247509 |
58 | Abnormality of the axillary hair (HP:0100134) | 2.29247509 |
59 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.28829459 |
60 | Absent/shortened dynein arms (HP:0200106) | 2.28829459 |
61 | Dysdiadochokinesis (HP:0002075) | 2.28761911 |
62 | Neurofibrillary tangles (HP:0002185) | 2.27764205 |
63 | Nephronophthisis (HP:0000090) | 2.27303325 |
64 | Abnormality of the corticospinal tract (HP:0002492) | 2.25260634 |
65 | Morphological abnormality of the pyramidal tract (HP:0002062) | 2.25189826 |
66 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.24608879 |
67 | Abnormality of the renal cortex (HP:0011035) | 2.23568130 |
68 | Hyperlipoproteinemia (HP:0010980) | 2.23154089 |
69 | Progressive inability to walk (HP:0002505) | 2.22460294 |
70 | Decreased circulating renin level (HP:0003351) | 2.20700520 |
71 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.20554054 |
72 | Increased circulating renin level (HP:0000848) | 2.20244846 |
73 | Anxiety (HP:0000739) | 2.20119933 |
74 | Hypothermia (HP:0002045) | 2.19757486 |
75 | EEG with generalized epileptiform discharges (HP:0011198) | 2.18991678 |
76 | Genital tract atresia (HP:0001827) | 2.18666233 |
77 | Poor eye contact (HP:0000817) | 2.16202897 |
78 | Epileptiform EEG discharges (HP:0011182) | 2.15934041 |
79 | Impaired social interactions (HP:0000735) | 2.14011513 |
80 | Abnormal social behavior (HP:0012433) | 2.14011513 |
81 | Xanthomatosis (HP:0000991) | 2.13254664 |
82 | Ketosis (HP:0001946) | 2.11977065 |
83 | Abnormal ciliary motility (HP:0012262) | 2.11870037 |
84 | Chronic hepatic failure (HP:0100626) | 2.11690362 |
85 | Hemiparesis (HP:0001269) | 2.11377098 |
86 | Short tibia (HP:0005736) | 2.10668673 |
87 | Congenital sensorineural hearing impairment (HP:0008527) | 2.09972244 |
88 | Protruding tongue (HP:0010808) | 2.09850124 |
89 | Abnormality of renin-angiotensin system (HP:0000847) | 2.09832543 |
90 | Hyperactive renin-angiotensin system (HP:0000841) | 2.09659092 |
91 | Gaze-evoked nystagmus (HP:0000640) | 2.09511542 |
92 | Hamartoma of the eye (HP:0010568) | 2.08472406 |
93 | Vaginal atresia (HP:0000148) | 2.07133484 |
94 | Decreased central vision (HP:0007663) | 2.06812922 |
95 | Medial flaring of the eyebrow (HP:0010747) | 2.06636130 |
96 | Akinesia (HP:0002304) | 2.06215898 |
97 | Torticollis (HP:0000473) | 2.05412016 |
98 | Generalized hypopigmentation of hair (HP:0011358) | 2.04690499 |
99 | Exotropia (HP:0000577) | 2.04682135 |
100 | Hyperglycinemia (HP:0002154) | 2.04195329 |
101 | Abnormality of salivation (HP:0100755) | 2.02883739 |
102 | Psychosis (HP:0000709) | 2.00894589 |
103 | Tubular atrophy (HP:0000092) | 2.00635301 |
104 | Generalized myoclonic seizures (HP:0002123) | 1.99508329 |
105 | Amblyopia (HP:0000646) | 1.97794951 |
106 | Abolished electroretinogram (ERG) (HP:0000550) | 1.97471816 |
107 | Hypokalemic alkalosis (HP:0001949) | 1.97273705 |
108 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.96062986 |
109 | Cutaneous finger syndactyly (HP:0010554) | 1.95265032 |
110 | Abnormality of glycine metabolism (HP:0010895) | 1.95105594 |
111 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.95105594 |
112 | Hypsarrhythmia (HP:0002521) | 1.94553112 |
113 | Parakeratosis (HP:0001036) | 1.94189274 |
114 | Ketoacidosis (HP:0001993) | 1.93888385 |
115 | Short 1st metacarpal (HP:0010034) | 1.92171003 |
116 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.92171003 |
117 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.91916969 |
118 | Hyperaldosteronism (HP:0000859) | 1.91752840 |
119 | Metabolic alkalosis (HP:0200114) | 1.91621215 |
120 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.91452616 |
121 | Fetal akinesia sequence (HP:0001989) | 1.91419703 |
122 | Goiter (HP:0000853) | 1.90690876 |
123 | Hyperglycinuria (HP:0003108) | 1.90005516 |
124 | Supranuclear gaze palsy (HP:0000605) | 1.89280660 |
125 | Intention tremor (HP:0002080) | 1.88935637 |
126 | Shawl scrotum (HP:0000049) | 1.88634646 |
127 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.88479121 |
128 | Cerebral inclusion bodies (HP:0100314) | 1.87245694 |
129 | Esotropia (HP:0000565) | 1.86904519 |
130 | Absent speech (HP:0001344) | 1.86835120 |
131 | Furrowed tongue (HP:0000221) | 1.86400245 |
132 | Molar tooth sign on MRI (HP:0002419) | 1.85416935 |
133 | Abnormality of midbrain morphology (HP:0002418) | 1.85416935 |
134 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.85302789 |
135 | Abnormality of cochlea (HP:0000375) | 1.85035434 |
136 | Focal dystonia (HP:0004373) | 1.84861793 |
137 | Poor suck (HP:0002033) | 1.84534594 |
138 | Polydipsia (HP:0001959) | 1.83189146 |
139 | Abnormal drinking behavior (HP:0030082) | 1.83189146 |
140 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.82520640 |
141 | Mixed hearing impairment (HP:0000410) | 1.82500166 |
142 | Polyuria (HP:0000103) | 1.81144801 |
143 | Preauricular pit (HP:0004467) | 1.79702911 |
144 | Periauricular skin pits (HP:0100277) | 1.79702911 |
145 | Megalencephaly (HP:0001355) | 1.79342649 |
146 | Congenital, generalized hypertrichosis (HP:0004540) | 1.79216247 |
147 | Dysmetria (HP:0001310) | 1.79153936 |
148 | Hypophosphatemic rickets (HP:0004912) | 1.79003835 |
149 | Hypokalemia (HP:0002900) | 1.77923902 |
150 | Craniofacial dystonia (HP:0012179) | 1.77750633 |
151 | Nephrogenic diabetes insipidus (HP:0009806) | 1.77369996 |
152 | Joint hemorrhage (HP:0005261) | 1.77253831 |
153 | Cupped ear (HP:0000378) | 1.75760178 |
154 | Hypomagnesemia (HP:0002917) | 1.74429303 |
155 | Pheochromocytoma (HP:0002666) | 1.74266582 |
156 | Down-sloping shoulders (HP:0200021) | 1.74155595 |
157 | Abnormality of proline metabolism (HP:0010907) | 1.73915980 |
158 | Hydroxyprolinuria (HP:0003080) | 1.73915980 |
159 | Hyperammonemia (HP:0001987) | 1.73883372 |
160 | Potter facies (HP:0002009) | 1.72927434 |
161 | Facial shape deformation (HP:0011334) | 1.72927434 |
162 | Hypochromic microcytic anemia (HP:0004840) | 1.72691997 |
163 | Inability to walk (HP:0002540) | 1.72500073 |
164 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.71076935 |
165 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.71076935 |
166 | Short 4th metacarpal (HP:0010044) | 1.70585095 |
167 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.70585095 |
168 | Complement deficiency (HP:0004431) | 1.69913608 |
169 | Amyotrophic lateral sclerosis (HP:0007354) | 1.69821493 |
170 | Gait imbalance (HP:0002141) | 1.69610983 |
171 | Methylmalonic acidemia (HP:0002912) | 1.69336498 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MARK1 | 5.49232618 |
2 | MAP3K4 | 3.13896328 |
3 | NTRK2 | 2.97973748 |
4 | MAP2K7 | 2.94962033 |
5 | PNCK | 2.80871617 |
6 | SIK2 | 2.77104079 |
7 | CASK | 2.61408312 |
8 | MAPK13 | 2.50843693 |
9 | NTRK3 | 2.24603955 |
10 | MAP2K4 | 2.16215543 |
11 | MAP4K2 | 1.96436429 |
12 | TIE1 | 1.94767825 |
13 | MAP3K9 | 1.94233110 |
14 | ACVR1B | 1.91252091 |
15 | TNIK | 1.89196435 |
16 | DYRK2 | 1.76911068 |
17 | MINK1 | 1.72247934 |
18 | EPHA4 | 1.69509320 |
19 | AKT3 | 1.60361977 |
20 | PHKG2 | 1.55543486 |
21 | PHKG1 | 1.55543486 |
22 | PINK1 | 1.49496462 |
23 | WNK3 | 1.48549481 |
24 | TRIM28 | 1.46661663 |
25 | DAPK2 | 1.44988389 |
26 | PAK6 | 1.42978870 |
27 | CAMK1G | 1.39763287 |
28 | SIK3 | 1.39302899 |
29 | KSR1 | 1.34191386 |
30 | PKN1 | 1.31845057 |
31 | INSRR | 1.31547655 |
32 | LMTK2 | 1.26196496 |
33 | MAP3K12 | 1.25070756 |
34 | OXSR1 | 1.22481405 |
35 | UHMK1 | 1.21200597 |
36 | EPHB2 | 1.14883693 |
37 | NUAK1 | 1.12507298 |
38 | CDK5 | 1.12260774 |
39 | TAOK3 | 1.11120910 |
40 | ERBB3 | 1.10822878 |
41 | TGFBR1 | 1.09136775 |
42 | BCR | 1.05990749 |
43 | PAK3 | 1.05830339 |
44 | STK38 | 1.03531991 |
45 | CSNK1G2 | 1.01357459 |
46 | SGK223 | 0.97460507 |
47 | SGK494 | 0.97460507 |
48 | DYRK1A | 0.96495857 |
49 | EPHA3 | 0.96489129 |
50 | PRKCG | 0.94390302 |
51 | SIK1 | 0.92603252 |
52 | CAMK2A | 0.91639344 |
53 | ADRBK1 | 0.91604814 |
54 | PIK3CA | 0.91473200 |
55 | WNK4 | 0.89171944 |
56 | MYLK | 0.87431138 |
57 | GRK5 | 0.86489089 |
58 | MAPK12 | 0.85128482 |
59 | PRKCZ | 0.84767542 |
60 | PLK2 | 0.82624742 |
61 | SGK3 | 0.82594749 |
62 | MARK2 | 0.81482897 |
63 | STK38L | 0.80072860 |
64 | FRK | 0.79661549 |
65 | PRKCE | 0.78984363 |
66 | NTRK1 | 0.77942635 |
67 | FGFR2 | 0.77741519 |
68 | SGK2 | 0.77019606 |
69 | MAP3K6 | 0.76165138 |
70 | CAMKK2 | 0.75855071 |
71 | STK39 | 0.75758475 |
72 | CAMK2B | 0.72885493 |
73 | STK11 | 0.72845874 |
74 | MKNK2 | 0.72467706 |
75 | CSNK1G3 | 0.71992640 |
76 | BMPR1B | 0.71165701 |
77 | LATS2 | 0.69753285 |
78 | MUSK | 0.67815047 |
79 | PRKG1 | 0.67809559 |
80 | MAPK4 | 0.67185912 |
81 | GRK1 | 0.67046706 |
82 | NLK | 0.66734812 |
83 | GRK7 | 0.64271776 |
84 | MAP3K7 | 0.64090554 |
85 | WNK1 | 0.62755539 |
86 | STK24 | 0.62026192 |
87 | ERBB4 | 0.59767979 |
88 | CSNK1A1L | 0.59568330 |
89 | LATS1 | 0.56863351 |
90 | TLK1 | 0.56264719 |
91 | SGK1 | 0.55885482 |
92 | CAMK4 | 0.55378812 |
93 | CDK18 | 0.54125124 |
94 | CAMK1 | 0.53721172 |
95 | MST1R | 0.53231401 |
96 | ERBB2 | 0.53090434 |
97 | CDK15 | 0.52223239 |
98 | NME1 | 0.52021091 |
99 | CAMKK1 | 0.51220153 |
100 | PRKACA | 0.50424630 |
101 | PRKAA1 | 0.50422988 |
102 | CSNK1G1 | 0.48537401 |
103 | IRAK2 | 0.48412244 |
104 | PRKCB | 0.47713170 |
105 | EIF2AK3 | 0.46712782 |
106 | FLT3 | 0.46529736 |
107 | BCKDK | 0.46341407 |
108 | CDK14 | 0.46212989 |
109 | PTK2B | 0.46099317 |
110 | CAMK2D | 0.45054729 |
111 | KIT | 0.45044734 |
112 | PRKACG | 0.44750835 |
113 | MAP2K1 | 0.44698050 |
114 | FER | 0.44623055 |
115 | CDK19 | 0.44337535 |
116 | CDK3 | 0.44194358 |
117 | PRKCH | 0.44015789 |
118 | CSNK1A1 | 0.43752383 |
119 | OBSCN | 0.43547505 |
120 | CAMK2G | 0.43095433 |
121 | ROCK1 | 0.42977083 |
122 | CDK11A | 0.42734053 |
123 | FES | 0.42654330 |
124 | FGR | 0.42648411 |
125 | ROCK2 | 0.40922628 |
126 | ADRBK2 | 0.40438696 |
127 | PDGFRB | 0.39376679 |
128 | PRKCA | 0.37476688 |
129 | ZAK | 0.37228028 |
130 | MAPKAPK3 | 0.37005783 |
131 | CSNK1D | 0.35519218 |
132 | RPS6KA2 | 0.34703958 |
133 | TGFBR2 | 0.34270920 |
134 | RPS6KB1 | 0.34251754 |
135 | ABL1 | 0.34251329 |
136 | PRKAA2 | 0.33273857 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.79465440 |
2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.13430624 |
3 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.58614391 |
4 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.25608847 |
5 | GABAergic synapse_Homo sapiens_hsa04727 | 2.23353248 |
6 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.13413050 |
7 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.12245910 |
8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.10343193 |
9 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.94927617 |
10 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.89315945 |
11 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.87397593 |
12 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.77107047 |
13 | Morphine addiction_Homo sapiens_hsa05032 | 1.76137913 |
14 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.74291253 |
15 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.72456644 |
16 | Taste transduction_Homo sapiens_hsa04742 | 1.70326686 |
17 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.64470691 |
18 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.62195221 |
19 | Circadian entrainment_Homo sapiens_hsa04713 | 1.57334254 |
20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.54098669 |
21 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.52646805 |
22 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.44028047 |
23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.43571531 |
24 | Bile secretion_Homo sapiens_hsa04976 | 1.39615210 |
25 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.38565517 |
26 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.34276713 |
27 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.31847306 |
28 | Olfactory transduction_Homo sapiens_hsa04740 | 1.24273491 |
29 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.24099766 |
30 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.19470619 |
31 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.19246960 |
32 | Salivary secretion_Homo sapiens_hsa04970 | 1.19107008 |
33 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.17645180 |
34 | Insulin secretion_Homo sapiens_hsa04911 | 1.17576623 |
35 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.17431676 |
36 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.17392196 |
37 | Long-term depression_Homo sapiens_hsa04730 | 1.15970899 |
38 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.15903213 |
39 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.14984997 |
40 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.14833548 |
41 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.13956468 |
42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.13539660 |
43 | Renin secretion_Homo sapiens_hsa04924 | 1.13349321 |
44 | Long-term potentiation_Homo sapiens_hsa04720 | 1.12377156 |
45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.11993490 |
46 | Cocaine addiction_Homo sapiens_hsa05030 | 1.11069696 |
47 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.10693840 |
48 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.10139985 |
49 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.09321602 |
50 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.09309062 |
51 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.09034426 |
52 | Axon guidance_Homo sapiens_hsa04360 | 1.07939449 |
53 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.06692156 |
54 | Phototransduction_Homo sapiens_hsa04744 | 1.06646507 |
55 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.06467377 |
56 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.05764932 |
57 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.05228908 |
58 | Peroxisome_Homo sapiens_hsa04146 | 1.04981746 |
59 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.04564200 |
60 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.02558587 |
61 | Retinol metabolism_Homo sapiens_hsa00830 | 1.00457580 |
62 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.98796224 |
63 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.98300820 |
64 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.96436295 |
65 | Alzheimers disease_Homo sapiens_hsa05010 | 0.93648606 |
66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.91884645 |
67 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.91468876 |
68 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.89867313 |
69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87606549 |
70 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.87418898 |
71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.87337571 |
72 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.87301925 |
73 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.83579317 |
74 | Histidine metabolism_Homo sapiens_hsa00340 | 0.83553198 |
75 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.83239520 |
76 | Protein export_Homo sapiens_hsa03060 | 0.82778141 |
77 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.78575817 |
78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.78240247 |
79 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.77154842 |
80 | Parkinsons disease_Homo sapiens_hsa05012 | 0.73501839 |
81 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.73400310 |
82 | ABC transporters_Homo sapiens_hsa02010 | 0.72786583 |
83 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.72668659 |
84 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.72054363 |
85 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.71963301 |
86 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.70931523 |
87 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.70254494 |
88 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.69700028 |
89 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.69143096 |
90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68896385 |
91 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.68431646 |
92 | Gap junction_Homo sapiens_hsa04540 | 0.68023223 |
93 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.66991703 |
94 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.64732318 |
95 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.63078716 |
96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.62005678 |
97 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.60757863 |
98 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.60359661 |
99 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.60356003 |
100 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.60090943 |
101 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.59084227 |
102 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.58761302 |
103 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.58686809 |
104 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.57699489 |
105 | Circadian rhythm_Homo sapiens_hsa04710 | 0.57575569 |
106 | Mineral absorption_Homo sapiens_hsa04978 | 0.57176297 |
107 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.52907697 |
108 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.51590229 |
109 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.51059598 |
110 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.50198065 |
111 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.50052219 |
112 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.49495787 |
113 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.48955508 |
114 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.48803524 |
115 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48736755 |
116 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.48341888 |
117 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.46780249 |
118 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.45972622 |
119 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.44078347 |
120 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.42517340 |
121 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.41127805 |
122 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.40699717 |
123 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.40215654 |
124 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.39908254 |
125 | Huntingtons disease_Homo sapiens_hsa05016 | 0.36337029 |
126 | Lysine degradation_Homo sapiens_hsa00310 | 0.36202691 |
127 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.35847325 |