RNF169

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.72597930
2bile acid and bile salt transport (GO:0015721)5.12774936
3tryptophan metabolic process (GO:0006568)5.00821841
4nuclear pore organization (GO:0006999)4.67669457
5indole-containing compound catabolic process (GO:0042436)4.56944102
6indolalkylamine catabolic process (GO:0046218)4.56944102
7tryptophan catabolic process (GO:0006569)4.56944102
8peptidyl-glutamic acid carboxylation (GO:0017187)4.56310599
9protein carboxylation (GO:0018214)4.56310599
10aromatic amino acid family catabolic process (GO:0009074)4.54019464
11erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)4.51126227
12L-phenylalanine catabolic process (GO:0006559)4.51126227
13complement activation, alternative pathway (GO:0006957)4.48735296
14urea cycle (GO:0000050)4.42472320
15urea metabolic process (GO:0019627)4.42472320
16regulation of protein activation cascade (GO:2000257)4.25608873
17positive regulation of gamma-delta T cell activation (GO:0046645)4.24962890
18kynurenine metabolic process (GO:0070189)4.23792209
19pore complex assembly (GO:0046931)4.15596464
20tyrosine metabolic process (GO:0006570)4.09719306
21L-phenylalanine metabolic process (GO:0006558)4.02704334
22erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.02704334
23triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.02652512
24regulation of complement activation (GO:0030449)4.01257568
25high-density lipoprotein particle remodeling (GO:0034375)3.96415201
26phospholipid homeostasis (GO:0055091)3.87762434
27homocysteine metabolic process (GO:0050667)3.80028990
28negative regulation of fibrinolysis (GO:0051918)3.78931128
29embryonic process involved in female pregnancy (GO:0060136)3.78074168
30dicarboxylic acid biosynthetic process (GO:0043650)3.74693826
31detection of molecule of bacterial origin (GO:0032490)3.73551538
32nitrogen cycle metabolic process (GO:0071941)3.72765865
33serine family amino acid catabolic process (GO:0009071)3.72518892
34bile acid biosynthetic process (GO:0006699)3.68259456
35phospholipid efflux (GO:0033700)3.58599738
36indolalkylamine metabolic process (GO:0006586)3.54637592
37regulation of triglyceride catabolic process (GO:0010896)3.54387626
38positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.48497529
39regulation of fibrinolysis (GO:0051917)3.48112057
40reverse cholesterol transport (GO:0043691)3.48008575
41alpha-linolenic acid metabolic process (GO:0036109)3.44653732
42regulation of RNA export from nucleus (GO:0046831)3.44483424
43phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.41867247
44cellular extravasation (GO:0045123)3.35622027
45negative regulation of erythrocyte differentiation (GO:0045647)3.35326269
46positive regulation by symbiont of host defense response (GO:0052509)3.33104606
47modulation by symbiont of host defense response (GO:0052031)3.33104606
48modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.33104606
49modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.33104606
50positive regulation by organism of defense response of other organism involved in symbiotic interact3.33104606
51modulation by symbiont of host immune response (GO:0052553)3.33104606
52dosage compensation (GO:0007549)3.24832022
53macrophage activation involved in immune response (GO:0002281)3.24320218
54negative regulation of cell killing (GO:0031342)3.22262691
55negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.22262691
56regulation of gamma-delta T cell differentiation (GO:0045586)3.20997830
57regulation of gamma-delta T cell activation (GO:0046643)3.20735320
58aromatic amino acid family metabolic process (GO:0009072)3.20564361
59pantothenate metabolic process (GO:0015939)3.20236313
60regulation of B cell receptor signaling pathway (GO:0050855)3.19887607
61protein-lipid complex remodeling (GO:0034368)3.19643427
62macromolecular complex remodeling (GO:0034367)3.19643427
63plasma lipoprotein particle remodeling (GO:0034369)3.19643427
64positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.17899844
65bile acid metabolic process (GO:0008206)3.17343203
66hypotonic response (GO:0006971)3.16694645
67regulation of nucleobase-containing compound transport (GO:0032239)3.15634877
68cholesterol efflux (GO:0033344)3.14495400
69positive regulation of glycoprotein biosynthetic process (GO:0010560)3.13386823
70fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.13164239
71plasma lipoprotein particle assembly (GO:0034377)3.12748300
72antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.11654076
73regulation of necroptotic process (GO:0060544)3.11402057
74amino-acid betaine metabolic process (GO:0006577)3.11116486
75mitotic sister chromatid cohesion (GO:0007064)3.10979520
76imidazole-containing compound metabolic process (GO:0052803)3.10847144
77histone H3-K9 demethylation (GO:0033169)3.09591433
78regulation of cholesterol esterification (GO:0010872)3.07145739
79glycine metabolic process (GO:0006544)3.06537725
80B cell receptor signaling pathway (GO:0050853)3.06535136
81positive regulation of respiratory burst (GO:0060267)3.06233280
82regulation of histone H3-K27 methylation (GO:0061085)3.05364970
83histone lysine demethylation (GO:0070076)3.04379647
84positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.04269078
85acylglycerol homeostasis (GO:0055090)3.03010072
86triglyceride homeostasis (GO:0070328)3.03010072
87response to muramyl dipeptide (GO:0032495)3.02665784
88response to peptidoglycan (GO:0032494)3.01225967
89negative regulation of sterol transport (GO:0032372)2.99970209
90negative regulation of cholesterol transport (GO:0032375)2.99970209
91acute-phase response (GO:0006953)2.98802960
92amine catabolic process (GO:0009310)2.98350592
93cellular biogenic amine catabolic process (GO:0042402)2.98350592
94hepatocyte apoptotic process (GO:0097284)2.97108748
95glyoxylate metabolic process (GO:0046487)2.96823835
96sulfur amino acid catabolic process (GO:0000098)2.95532673
97cellular glucuronidation (GO:0052695)2.95095781
98detection of external biotic stimulus (GO:0098581)2.94900955
99detection of other organism (GO:0098543)2.94770654
100cellular response to ethanol (GO:0071361)2.91254069
101histone demethylation (GO:0016577)2.91248258
102definitive hemopoiesis (GO:0060216)2.89792629
103positive regulation of lipid catabolic process (GO:0050996)2.89236724
104monoubiquitinated protein deubiquitination (GO:0035520)2.87885232
105protein-lipid complex assembly (GO:0065005)2.85774401
106alpha-amino acid catabolic process (GO:1901606)2.83568064
107low-density lipoprotein particle remodeling (GO:0034374)2.82073719
108complement activation (GO:0006956)2.81957337
109regulation of interferon-beta biosynthetic process (GO:0045357)2.80735916
110killing of cells in other organism involved in symbiotic interaction (GO:0051883)2.78882427
111disruption of cells of other organism involved in symbiotic interaction (GO:0051818)2.78882427
112plasma lipoprotein particle clearance (GO:0034381)2.78833237
113complement activation, classical pathway (GO:0006958)2.78693529
114germinal center formation (GO:0002467)2.78561793
115cytoplasmic mRNA processing body assembly (GO:0033962)2.75627994
116iron ion import (GO:0097286)2.75365429
117fibrinolysis (GO:0042730)2.75262448
118coenzyme A biosynthetic process (GO:0015937)2.74497904
119very-low-density lipoprotein particle assembly (GO:0034379)2.72603963
120protein activation cascade (GO:0072376)2.70946310
121positive regulation of fatty acid beta-oxidation (GO:0032000)2.70731201
122lipoprotein metabolic process (GO:0042157)2.69973561
123peptidyl-threonine phosphorylation (GO:0018107)2.69762317
124plasma lipoprotein particle organization (GO:0071827)2.69417932
125positive regulation of cellular amide metabolic process (GO:0034250)2.69184814
126regulation of NFAT protein import into nucleus (GO:0051532)2.67526374
127positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.64938713
128regulation of humoral immune response (GO:0002920)2.63611091
129antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.62118613
130peptidyl-threonine modification (GO:0018210)2.62052578
131pre-miRNA processing (GO:0031054)2.61753701
132cholesterol homeostasis (GO:0042632)2.61100384
133macrophage activation (GO:0042116)2.60495401
134sterol homeostasis (GO:0055092)2.60415017
135glutamate metabolic process (GO:0006536)2.60011733
136detection of biotic stimulus (GO:0009595)2.60000780
137indole-containing compound metabolic process (GO:0042430)2.59805136
138negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.59531122
139negative regulation of translation, ncRNA-mediated (GO:0040033)2.59531122
140regulation of translation, ncRNA-mediated (GO:0045974)2.59531122
141response to host (GO:0075136)2.58811529
142response to host defenses (GO:0052200)2.58811529
143response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.58811529
144negative regulation of lipase activity (GO:0060192)2.57256348
145thrombin receptor signaling pathway (GO:0070493)2.56732293
146protein-lipid complex subunit organization (GO:0071825)2.56551175
147interkinetic nuclear migration (GO:0022027)2.56396538
148arginine metabolic process (GO:0006525)2.55816124
149response to laminar fluid shear stress (GO:0034616)2.54687283
150histone H3-K36 demethylation (GO:0070544)2.54556589
151neutrophil mediated immunity (GO:0002446)2.53823979
152histone H3-K4 trimethylation (GO:0080182)2.53059701
153cysteine metabolic process (GO:0006534)2.52995053
154regulation of plasminogen activation (GO:0010755)2.52344874
155negative regulation of granulocyte differentiation (GO:0030853)2.50192647
156protein localization to endosome (GO:0036010)2.49880349
157negative regulation of protein activation cascade (GO:2000258)2.48601799
158cytolysis (GO:0019835)2.47906818
159negative regulation of necroptotic process (GO:0060546)2.47576090
160negative regulation of interleukin-12 production (GO:0032695)2.46604003
161protein dealkylation (GO:0008214)2.46085125
162protein demethylation (GO:0006482)2.46085125
163detection of bacterium (GO:0016045)2.45402690
164negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.45302494
165antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.45285259
166response to host immune response (GO:0052572)2.45271078
167response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.45271078
168cellular response to fluid shear stress (GO:0071498)2.44345345
169positive regulation of protein import into nucleus, translocation (GO:0033160)2.43262858
170positive regulation of interferon-alpha production (GO:0032727)2.43246270
171peptidyl-lysine trimethylation (GO:0018023)2.42721813
172antigen processing and presentation of endogenous antigen (GO:0019883)2.42387802
173neutrophil activation involved in immune response (GO:0002283)2.41234894
174negative thymic T cell selection (GO:0045060)2.40019174
175positive T cell selection (GO:0043368)2.39885447
176positive regulation of granulocyte differentiation (GO:0030854)2.38724185
177embryonic camera-type eye morphogenesis (GO:0048596)2.37870856
178leukocyte aggregation (GO:0070486)2.36583485
179microglial cell activation (GO:0001774)2.34563349
180histone H3-K4 methylation (GO:0051568)2.34452247
181negative T cell selection (GO:0043383)2.34122743
182positive thymic T cell selection (GO:0045059)2.32163869
183response to interleukin-15 (GO:0070672)2.31434870
184negative regulation of T cell mediated immunity (GO:0002710)2.31430812
185positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.27484348
186production of molecular mediator involved in inflammatory response (GO:0002532)2.27356516
187megakaryocyte development (GO:0035855)2.25789316
188necrotic cell death (GO:0070265)2.23896887
189negative regulation of lymphocyte mediated immunity (GO:0002707)2.23853784
190positive regulation of B cell differentiation (GO:0045579)2.22147092
191negative regulation of myotube differentiation (GO:0010832)2.22077457
192necroptotic process (GO:0070266)2.21657846
193positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.20672894
194lipopolysaccharide-mediated signaling pathway (GO:0031663)2.18794863
195antigen processing and presentation via MHC class Ib (GO:0002475)2.18725119
196T cell selection (GO:0045058)2.18644410

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.88103493
2* RXR_22158963_ChIP-Seq_LIVER_Mouse4.36376050
3EGR1_23403033_ChIP-Seq_LIVER_Mouse3.95133480
4LXR_22158963_ChIP-Seq_LIVER_Mouse3.76676302
5* PPARA_22158963_ChIP-Seq_LIVER_Mouse3.69249283
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.34550972
7NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.07598474
8IRF8_22096565_ChIP-ChIP_GC-B_Human2.93808539
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.93173386
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.71397694
11FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.51185237
12NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.48682428
13STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.38959971
14E2F7_22180533_ChIP-Seq_HELA_Human2.35801493
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.34806915
16EGR1_19374776_ChIP-ChIP_THP-1_Human2.31540680
17GATA1_22025678_ChIP-Seq_K562_Human2.10276453
18SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.09205275
19Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.03823946
20VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.02430064
21SCL_19346495_ChIP-Seq_HPC-7_Human2.01477155
22RUNX_20019798_ChIP-Seq_JUKART_Human1.92729678
23VDR_21846776_ChIP-Seq_THP-1_Human1.89693352
24CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.88541908
25IRF8_21731497_ChIP-ChIP_J774_Mouse1.81860122
26KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.79449873
27VDR_24763502_ChIP-Seq_THP-1_Human1.74680737
28IRF8_27001747_Chip-Seq_BMDM_Mouse1.72859198
29* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.67606652
30KDM2B_26808549_Chip-Seq_SUP-B15_Human1.67135242
31FOXA2_19822575_ChIP-Seq_HepG2_Human1.64116691
32TP53_16413492_ChIP-PET_HCT116_Human1.62909263
33* TCF7_22412390_ChIP-Seq_EML_Mouse1.57944320
34STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.57232612
35BRD4_27068464_Chip-Seq_AML-cells_Mouse1.56066213
36KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.55474726
37MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.52603569
38CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.49889719
39MYB_21317192_ChIP-Seq_ERMYB_Mouse1.49451865
40* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.48973662
41* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.48973662
42TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.48751209
43ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.46509711
44IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.46450370
45FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.46272388
46FOXM1_23109430_ChIP-Seq_U2OS_Human1.45828199
47* SPI1_23547873_ChIP-Seq_NB4_Human1.40105165
48TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.39204854
49FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.38260675
50* KDM2B_26808549_Chip-Seq_JURKAT_Human1.37796434
51KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.36043633
52CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.35718655
53* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.34655842
54STAT4_19710469_ChIP-ChIP_TH1__Mouse1.34390336
55ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.32616938
56ESR1_15608294_ChIP-ChIP_MCF-7_Human1.28850193
57GATA2_21666600_ChIP-Seq_HMVEC_Human1.28326586
58ZNF217_24962896_ChIP-Seq_MCF-7_Human1.28020636
59UTX_26944678_Chip-Seq_JUKART_Human1.26602676
60SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.22878090
61SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.21571577
62SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.17904756
63GATA1_19941826_ChIP-Seq_K562_Human1.17346851
64NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.17105130
65SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.15780307
66SALL4_18804426_ChIP-ChIP_XEN_Mouse1.15221981
67FOXO3_23340844_ChIP-Seq_DLD1_Human1.14839447
68SALL1_21062744_ChIP-ChIP_HESCs_Human1.10172985
69ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.09233001
70RXR_22108803_ChIP-Seq_LS180_Human1.08759366
71MYC_22102868_ChIP-Seq_BL_Human1.08314226
72GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.08218132
73* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.07720833
74ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.07040989
75GATA3_27048872_Chip-Seq_THYMUS_Human1.06536211
76GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.06434795
77E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.06012816
78PPAR_26484153_Chip-Seq_NCI-H1993_Human1.05522463
79ELK3_25401928_ChIP-Seq_HUVEC_Human1.03996738
80BP1_19119308_ChIP-ChIP_Hs578T_Human1.03571265
81VDR_24787735_ChIP-Seq_THP-1_Human1.03536521
82GATA2_22383799_ChIP-Seq_G1ME_Mouse1.03475474
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.01634624
84* CHD1_26751641_Chip-Seq_LNCaP_Human1.01565918
85STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.01369722
86PU_27001747_Chip-Seq_BMDM_Mouse1.00795393
87SPI1_23127762_ChIP-Seq_K562_Human1.00414268
88MYB_26560356_Chip-Seq_TH1_Human1.00268781
89AHR_22903824_ChIP-Seq_MCF-7_Human1.00175154
90* HNF4A_19822575_ChIP-Seq_HepG2_Human0.99596115
91BRD4_25478319_ChIP-Seq_HGPS_Human0.99400599
92RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.96726799
93RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.96102765
94ESR1_21235772_ChIP-Seq_MCF-7_Human0.96091683
95RUNX1_27514584_Chip-Seq_MCF-7_Human0.94757906
96* KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.94742594
97RUNX1_22412390_ChIP-Seq_EML_Mouse0.94009164
98UBF1/2_26484160_Chip-Seq_HMECs_Human0.93832786
99CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.93592556
100TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.92976179
101ESR2_21235772_ChIP-Seq_MCF-7_Human0.92907168
102PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse0.92834004
103ESR1_20079471_ChIP-ChIP_T-47D_Human0.92314000
104SOX9_24532713_ChIP-Seq_HFSC_Mouse0.91815644
105NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.91727769
106* MAF_26560356_Chip-Seq_TH2_Human0.91440355
107NCOR1_26117541_ChIP-Seq_K562_Human0.91378794
108TFEB_21752829_ChIP-Seq_HELA_Human0.90981626
109AR_21572438_ChIP-Seq_LNCaP_Human0.90566052
110GATA1_19941827_ChIP-Seq_MEL_Mouse0.90271145
111FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89455852
112ARNT_22903824_ChIP-Seq_MCF-7_Human0.88962681
113SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.88092475
114* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.87331752
115CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.86913246
116PKCTHETA_26484144_Chip-Seq_BREAST_Human0.85369088
117MAF_26560356_Chip-Seq_TH1_Human0.84894046
118AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.84586671
119CDX2_20551321_ChIP-Seq_CACO-2_Human0.84326399
120SOX2_27498859_Chip-Seq_STOMACH_Mouse0.84277140
121TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.84050586
122TP63_17297297_ChIP-ChIP_HaCaT_Human0.83629976
123FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.82900152
124BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82667020
125TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.81538176
126CLOCK_20551151_ChIP-Seq_293T_Human0.80646144
127CTNNB1_20460455_ChIP-Seq_HCT116_Human0.80218706
128PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78202878
129BCAT_22108803_ChIP-Seq_LS180_Human0.78109804
130ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.77875046
131TCF4_18268006_ChIP-ChIP_LS174T_Human0.77043563
132DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.76670557
133GATA2_19941826_ChIP-Seq_K562_Human0.76238623
134SMAD_19615063_ChIP-ChIP_OVARY_Human0.76025521
135SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75881387
136KDM2B_26808549_Chip-Seq_DND41_Human0.75737835
137MYB_26560356_Chip-Seq_TH2_Human0.75555727
138NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.74633485
139NRF2_20460467_ChIP-Seq_MEFs_Mouse0.74633485

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system5.56443585
2MP0010234_abnormal_vibrissa_follicle5.26982689
3MP0005360_urolithiasis4.89149846
4MP0005085_abnormal_gallbladder_physiolo4.43899334
5MP0005365_abnormal_bile_salt4.11293181
6MP0003252_abnormal_bile_duct3.74829067
7MP0008875_abnormal_xenobiotic_pharmacok2.80038125
8MP0002138_abnormal_hepatobiliary_system2.79598722
9MP0010329_abnormal_lipoprotein_level2.52294240
10MP0000569_abnormal_digit_pigmentation2.41769668
11MP0005451_abnormal_body_composition2.31594987
12MP0003724_increased_susceptibility_to2.17190843
13MP0003191_abnormal_cellular_cholesterol2.03115950
14MP0002166_altered_tumor_susceptibility1.97647871
15MP0003828_pulmonary_edema1.96850858
16MP0001835_abnormal_antigen_presentation1.93768815
17MP0009697_abnormal_copulation1.92452125
18MP0005409_darkened_coat_color1.88338281
19MP0003300_gastrointestinal_ulcer1.77613638
20MP0004185_abnormal_adipocyte_glucose1.77129597
21MP0000609_abnormal_liver_physiology1.69398592
22MP0010678_abnormal_skin_adnexa1.68115667
23MP0003656_abnormal_erythrocyte_physiolo1.66735524
24MP0003705_abnormal_hypodermis_morpholog1.66640351
25MP0005076_abnormal_cell_differentiation1.65185361
26MP0009840_abnormal_foam_cell1.63720900
27MP0002928_abnormal_bile_duct1.59734684
28MP0005464_abnormal_platelet_physiology1.57507098
29MP0002396_abnormal_hematopoietic_system1.56707455
30MP0004381_abnormal_hair_follicle1.56160428
31MP0008260_abnormal_autophagy1.52709532
32MP0004264_abnormal_extraembryonic_tissu1.51151138
33MP0010352_gastrointestinal_tract_polyps1.49569735
34MP0008057_abnormal_DNA_replication1.44878302
35MP0004808_abnormal_hematopoietic_stem1.40056595
36MP0001545_abnormal_hematopoietic_system1.38168464
37MP0005397_hematopoietic_system_phenotyp1.38168464
38MP0003221_abnormal_cardiomyocyte_apopto1.37663715
39MP0003806_abnormal_nucleotide_metabolis1.36269646
40MP0000703_abnormal_thymus_morphology1.36177259
41MP0001851_eye_inflammation1.35805176
42MP0003943_abnormal_hepatobiliary_system1.35790626
43MP0002006_tumorigenesis1.35737466
44MP0003436_decreased_susceptibility_to1.34066171
45MP0000383_abnormal_hair_follicle1.31486370
46MP0010307_abnormal_tumor_latency1.31193248
47MP0004233_abnormal_muscle_weight1.30960462
48MP0002876_abnormal_thyroid_physiology1.26384950
49MP0002405_respiratory_system_inflammati1.26209957
50MP0001666_abnormal_nutrient_absorption1.25807140
51MP0002877_abnormal_melanocyte_morpholog1.24368471
52MP0001915_intracranial_hemorrhage1.23804295
53MP0005319_abnormal_enzyme/_coenzyme1.22457112
54MP0000465_gastrointestinal_hemorrhage1.18229418
55MP0001800_abnormal_humoral_immune1.16967336
56MP0005621_abnormal_cell_physiology1.16096388
57MP0002118_abnormal_lipid_homeostasis1.14938791
58MP0000015_abnormal_ear_pigmentation1.14023727
59MP0009764_decreased_sensitivity_to1.13892452
60MP0000598_abnormal_liver_morphology1.12670509
61MP0009053_abnormal_anal_canal1.12253370
62MP0001790_abnormal_immune_system1.11077050
63MP0005387_immune_system_phenotype1.11077050
64MP0005083_abnormal_biliary_tract1.10204142
65MP0003172_abnormal_lysosome_physiology1.08475447
66MP0004130_abnormal_muscle_cell1.07734768
67MP0002998_abnormal_bone_remodeling1.07649423
68MP0005671_abnormal_response_to1.06405063
69MP0000685_abnormal_immune_system1.05158525
70MP0003868_abnormal_feces_composition1.04903275
71MP0000733_abnormal_muscle_development1.04841918
72MP0005332_abnormal_amino_acid1.04113989
73MP0002086_abnormal_extraembryonic_tissu1.01948450
74MP0005666_abnormal_adipose_tissue1.01004080
75MP0003890_abnormal_embryonic-extraembry1.00692513
76MP0000858_altered_metastatic_potential1.00635156
77MP0005174_abnormal_tail_pigmentation1.00010634
78MP0002419_abnormal_innate_immunity0.98520318
79MP0004019_abnormal_vitamin_homeostasis0.98156301
80MP0009763_increased_sensitivity_to0.97704138
81MP0002332_abnormal_exercise_endurance0.97454317
82MP0003183_abnormal_peptide_metabolism0.96732385
83MP0004947_skin_inflammation0.96732136
84MP0002429_abnormal_blood_cell0.96151715
85MP0000371_diluted_coat_color0.95551898
86MP0003984_embryonic_growth_retardation0.93362738
87MP0004883_abnormal_blood_vessel0.92919394
88MP0003303_peritoneal_inflammation0.91600571
89MP0002088_abnormal_embryonic_growth/wei0.90911220
90MP0003045_fibrosis0.90672222
91MP0003453_abnormal_keratinocyte_physiol0.90394481
92MP0009115_abnormal_fat_cell0.90065217
93MP0002254_reproductive_system_inflammat0.89989897
94MP0008961_abnormal_basal_metabolism0.89671353
95MP0003077_abnormal_cell_cycle0.89510257
96MP0005584_abnormal_enzyme/coenzyme_acti0.89481025
97MP0005275_abnormal_skin_tensile0.87991109
98MP0002009_preneoplasia0.87817442
99MP0010368_abnormal_lymphatic_system0.86781262
100MP0001533_abnormal_skeleton_physiology0.86678293
101MP0002452_abnormal_antigen_presenting0.86473781
102MP0000350_abnormal_cell_proliferation0.86344807
103MP0005164_abnormal_response_to0.85650755
104MP0010630_abnormal_cardiac_muscle0.83884387
105MP0003279_aneurysm0.83771433
106MP0000604_amyloidosis0.83331559
107MP0002796_impaired_skin_barrier0.82815645
108MP0000689_abnormal_spleen_morphology0.82079892
109MP0002148_abnormal_hypersensitivity_rea0.81480077
110MP0005375_adipose_tissue_phenotype0.80919581
111MP0002398_abnormal_bone_marrow0.80840526
112MP0003448_altered_tumor_morphology0.80825223
113MP0008469_abnormal_protein_level0.79378695
114MP0005023_abnormal_wound_healing0.79250884
115MP0005025_abnormal_response_to0.79026927
116MP0009278_abnormal_bone_marrow0.77955343
117MP0003763_abnormal_thymus_physiology0.77714508
118MP0001672_abnormal_embryogenesis/_devel0.77596783
119MP0005380_embryogenesis_phenotype0.77596783
120MP0002723_abnormal_immune_serum0.76885778
121MP0010155_abnormal_intestine_physiology0.76780093
122MP0003787_abnormal_imprinting0.76736272
123MP0005408_hypopigmentation0.76477293
124MP0009765_abnormal_xenobiotic_induced0.74422356
125MP0001819_abnormal_immune_cell0.74300633
126MP0005384_cellular_phenotype0.73010162
127MP0005310_abnormal_salivary_gland0.72985580
128MP0002420_abnormal_adaptive_immunity0.72091693
129MP0002019_abnormal_tumor_incidence0.71837458
130MP0001853_heart_inflammation0.71379794
131MP0001243_abnormal_dermal_layer0.71057363
132MP0003866_abnormal_defecation0.70865326
133MP0005000_abnormal_immune_tolerance0.70495424
134MP0003566_abnormal_cell_adhesion0.70482149
135MP0002722_abnormal_immune_system0.69811037
136MP0001216_abnormal_epidermal_layer0.69666517
137MP0003011_delayed_dark_adaptation0.68822508
138MP0003075_altered_response_to0.68784597
139MP0001845_abnormal_inflammatory_respons0.68065175
140MP0000716_abnormal_immune_system0.67476288
141MP0003091_abnormal_cell_migration0.67271410
142MP0000427_abnormal_hair_cycle0.66007142
143MP0009931_abnormal_skin_appearance0.64325372
144MP0009785_altered_susceptibility_to0.64290157
145MP0002060_abnormal_skin_morphology0.64128202
146MP0000377_abnormal_hair_follicle0.63570913

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)4.70298448
2Deep venous thrombosis (HP:0002625)4.69164365
3Complement deficiency (HP:0004431)4.51102503
4Abnormality of monocarboxylic acid metabolism (HP:0010996)4.40451370
5Abnormality of complement system (HP:0005339)3.56883842
6Abnormality of the fingertips (HP:0001211)3.56090658
7Eczematoid dermatitis (HP:0000976)3.53920771
8Joint hemorrhage (HP:0005261)3.50445640
9Prolonged partial thromboplastin time (HP:0003645)3.48605362
10Xanthomatosis (HP:0000991)3.33956048
11Hypobetalipoproteinemia (HP:0003563)3.29387640
12Spontaneous hematomas (HP:0007420)3.15987702
13Abnormality of aromatic amino acid family metabolism (HP:0004338)3.11553352
14Hypochromic microcytic anemia (HP:0004840)3.05710058
15Abnormality of sulfur amino acid metabolism (HP:0004339)3.01673825
16Conjugated hyperbilirubinemia (HP:0002908)2.95248202
17Epidermoid cyst (HP:0200040)2.90611002
18Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.89481010
19Papillary thyroid carcinoma (HP:0002895)2.89096962
20Recurrent abscess formation (HP:0002722)2.87361757
21Abnormality of pyrimidine metabolism (HP:0004353)2.87213532
22Hyperlipoproteinemia (HP:0010980)2.83940485
23Acute myeloid leukemia (HP:0004808)2.80662426
24Abnormality of the common coagulation pathway (HP:0010990)2.79451038
25Myocardial infarction (HP:0001658)2.79048077
26Esophageal varix (HP:0002040)2.76328082
27Systemic lupus erythematosus (HP:0002725)2.74920654
28Abnormality of methionine metabolism (HP:0010901)2.71364991
29Hepatocellular carcinoma (HP:0001402)2.70342768
30Recurrent gram-negative bacterial infections (HP:0005420)2.63375230
31Mitral stenosis (HP:0001718)2.62884656
32T lymphocytopenia (HP:0005403)2.61071175
33Panhypogammaglobulinemia (HP:0003139)2.58418778
34Abnormality of glutamine family amino acid metabolism (HP:0010902)2.58241243
35Gingivitis (HP:0000230)2.56764081
36Ankyloglossia (HP:0010296)2.54101297
37Hypercholesterolemia (HP:0003124)2.52896415
38Recurrent viral infections (HP:0004429)2.50203980
39Abnormality of aspartate family amino acid metabolism (HP:0010899)2.49553579
40Deep philtrum (HP:0002002)2.49439650
41Hypolipoproteinemia (HP:0010981)2.47005895
42Gingival bleeding (HP:0000225)2.46083605
43Hypoplasia of the thymus (HP:0000778)2.43743343
44Bile duct proliferation (HP:0001408)2.43735007
45Abnormal biliary tract physiology (HP:0012439)2.43735007
46Osteolytic defects of the phalanges of the hand (HP:0009771)2.42292382
47Osteolytic defects of the hand bones (HP:0009699)2.42292382
48Hematochezia (HP:0002573)2.36023725
49Hepatitis (HP:0012115)2.33971869
50Abnormal delayed hypersensitivity skin test (HP:0002963)2.33823240
51Viral hepatitis (HP:0006562)2.31175188
52Hypoalphalipoproteinemia (HP:0003233)2.30331108
53Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.29553621
54Cellulitis (HP:0100658)2.26670388
55Glomerulonephritis (HP:0000099)2.26309431
56Dislocated radial head (HP:0003083)2.26222961
57Volvulus (HP:0002580)2.26068534
58Abnormality of oral frenula (HP:0000190)2.24226191
59Asymmetry of the thorax (HP:0001555)2.23805209
60Subacute progressive viral hepatitis (HP:0006572)2.20219621
61Acanthocytosis (HP:0001927)2.19741249
62Autoimmune thrombocytopenia (HP:0001973)2.15300240
63Fair hair (HP:0002286)2.14387798
64Slow saccadic eye movements (HP:0000514)2.12995082
65Neonatal hypoglycemia (HP:0001998)2.12429464
66Broad face (HP:0000283)2.11205179
67Flat acetabular roof (HP:0003180)2.09159170
68Recurrent fungal infections (HP:0002841)2.08892324
69Overgrowth (HP:0001548)2.06832554
70Hypochromic anemia (HP:0001931)2.04637676
71Heterotopia (HP:0002282)2.04009264
72Gastrointestinal infarctions (HP:0005244)2.03942117
73Abnormality of the left ventricular outflow tract (HP:0011103)2.02766694
74Subaortic stenosis (HP:0001682)2.02766694
75Abnormality of the radial head (HP:0003995)2.01395569
76Arterial tortuosity (HP:0005116)2.00835987
77Fat malabsorption (HP:0002630)2.00800010
78Absent frontal sinuses (HP:0002688)1.99662038
79Orchitis (HP:0100796)1.98107141
80Macroorchidism (HP:0000053)1.97813630
81Fatigue (HP:0012378)1.97770228
82Thrombophlebitis (HP:0004418)1.97682275
83Sandal gap (HP:0001852)1.96933743
84Narrow palate (HP:0000189)1.96150471
85Myositis (HP:0100614)1.95667706
86Spinal cord lesions (HP:0100561)1.95445144
87Syringomyelia (HP:0003396)1.95445144
88Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.95398907
89Chronic hepatic failure (HP:0100626)1.95370567
90Thyroiditis (HP:0100646)1.95242966
91Arterial thrombosis (HP:0004420)1.95163097
92Increased IgE level (HP:0003212)1.94684351
93Spontaneous abortion (HP:0005268)1.93702888
94Inflammation of the large intestine (HP:0002037)1.92690242
95Colitis (HP:0002583)1.91452318
96Periodontitis (HP:0000704)1.90330390
97Abnormality of the intrinsic pathway (HP:0010989)1.89830125
98Prominent nose (HP:0000448)1.89451535
99Mediastinal lymphadenopathy (HP:0100721)1.89245757
100Optic neuritis (HP:0100653)1.89238615
101Retrobulbar optic neuritis (HP:0100654)1.89238615
102Agammaglobulinemia (HP:0004432)1.88942917
103Gastrointestinal inflammation (HP:0004386)1.88848712
104Interstitial pulmonary disease (HP:0006530)1.88381292
105Abnormality of the distal phalanx of the thumb (HP:0009617)1.87563671
106Skin nodule (HP:0200036)1.87410102
107Pulmonary embolism (HP:0002204)1.86062561
108Persistence of primary teeth (HP:0006335)1.86017092
109Aortic aneurysm (HP:0004942)1.85659245
110Truncal obesity (HP:0001956)1.85584549
111Recurrent bacterial skin infections (HP:0005406)1.84751652
112Abnormality of macrophages (HP:0004311)1.84428674
113Hyperammonemia (HP:0001987)1.83138215
114Difficulty running (HP:0009046)1.82618406
115Neoplasm of the tracheobronchial system (HP:0100552)1.82050229
116Distal lower limb amyotrophy (HP:0008944)1.81820668
117Ketosis (HP:0001946)1.81078571
118Relative macrocephaly (HP:0004482)1.79076703
119Urethral obstruction (HP:0000796)1.78086907
120Recurrent cutaneous fungal infections (HP:0011370)1.77864927
121Chronic mucocutaneous candidiasis (HP:0002728)1.77864927
122Alopecia of scalp (HP:0002293)1.77012230
123Mitral valve prolapse (HP:0001634)1.76029623
124Osteomyelitis (HP:0002754)1.75000841
125Curly hair (HP:0002212)1.74958573
126Autoimmune hemolytic anemia (HP:0001890)1.74729840
127Germ cell neoplasia (HP:0100728)1.74441973
128Low anterior hairline (HP:0000294)1.74372476
129Nephritis (HP:0000123)1.74114614
130Chest pain (HP:0100749)1.73963045
131Micronodular cirrhosis (HP:0001413)1.73411082
132Sparse lateral eyebrow (HP:0005338)1.72747116
133Thick nail (HP:0001805)1.72244709
134Spastic diplegia (HP:0001264)1.70150815
135Vertebral arch anomaly (HP:0008438)1.70080020
136Neoplasm of the liver (HP:0002896)1.69981588
137Epistaxis (HP:0000421)1.68432205
138Amyloidosis (HP:0011034)1.68047914
139Vascular tortuosity (HP:0004948)1.67972738
140Dilatation of the ascending aorta (HP:0005111)1.67731470
141Transitional cell carcinoma of the bladder (HP:0006740)1.67480896
142Portal hypertension (HP:0001409)1.67462781
143Eosinophilia (HP:0001880)1.67279818
144Peritonitis (HP:0002586)1.66766563
145Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.66511951
146Increased connective tissue (HP:0009025)1.66104592
147Cubitus valgus (HP:0002967)1.65726008
148Bladder neoplasm (HP:0009725)1.65598396
149Keratoconjunctivitis sicca (HP:0001097)1.65057770
150Conjunctival telangiectasia (HP:0000524)1.64865754
151Generalized hypopigmentation of hair (HP:0011358)1.64582421
152Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.64014544
153Abnormality of the peritoneum (HP:0002585)1.63996838
154Cystic hygroma (HP:0000476)1.63988147
155Hyperglycinemia (HP:0002154)1.63932974
156Recurrent skin infections (HP:0001581)1.62944657
157Agnosia (HP:0010524)1.62463617
158Abnormality of the vasculature of the conjunctiva (HP:0008054)1.62305658
159Thyroid carcinoma (HP:0002890)1.60693562
160Long eyelashes (HP:0000527)1.59698660
161Coarse hair (HP:0002208)1.59408833
162Vascular calcification (HP:0004934)1.58168303
163Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.57420165
164Leiomyosarcoma (HP:0100243)1.56795261
165Abnormality of the hepatic vasculature (HP:0006707)1.54659462
166Spondylolisthesis (HP:0003302)1.54271337
167Abnormality of T cell number (HP:0011839)1.54098215
168Abnormal platelet volume (HP:0011876)1.54024546
169Dysmetric saccades (HP:0000641)1.52670588
170Short 4th metacarpal (HP:0010044)1.52349280
171Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.52349280
172Obsessive-compulsive behavior (HP:0000722)1.51577961
173Hyperbilirubinemia (HP:0002904)1.51242943
174Bladder carcinoma (HP:0002862)1.50800091

Predicted kinase interactions (KEA)

RankGene SetZ-score
1RIPK13.52937947
2FRK3.17639464
3PRPF4B2.93621819
4STK32.82663262
5MAP3K142.81656587
6CDK122.58402103
7TRIB32.49389036
8INSRR2.09703046
9BLK2.01753512
10PIK3CA1.99328781
11STK101.96882035
12LATS11.91974011
13SGK21.90999344
14SGK31.86418446
15CDK61.84554498
16TYK21.82154876
17ZAK1.81853232
18ICK1.81695944
19TAOK31.70726855
20TTN1.63744377
21MAP2K31.63407776
22FGFR21.51272852
23STK241.45495894
24IRAK41.44570867
25TAOK11.43770189
26CAMK1D1.41851955
27BMPR21.40936386
28MAPK71.37576797
29NUAK11.35624393
30SIK11.35334138
31PTK61.35041987
32WNK11.34281309
33MARK21.33853890
34MAP3K61.33808052
35KSR21.32924205
36MAP3K101.31663680
37PKN21.29594817
38SCYL21.29231450
39ERN11.24453927
40FGFR31.23683797
41ZAP701.23405687
42FES1.18059529
43CDK41.17168026
44CHUK1.16949671
45BRD41.14567913
46PDGFRA1.14339491
47SIK21.14254505
48MAP3K31.14135390
49MAP4K11.13006366
50PIK3CG1.11269227
51FLT31.10995323
52RIPK41.09243693
53NEK91.07205476
54JAK11.06364634
55MAP3K11.05697461
56AKT31.05587155
57FGFR41.04492923
58TAOK21.03988720
59SIK31.03850841
60NEK61.02946691
61PIM11.02781754
62TGFBR21.02047436
63CAMK1G0.98709349
64EEF2K0.98397974
65SMG10.96600443
66CSF1R0.95816835
67IKBKB0.95542957
68JAK30.94751790
69GRK60.91946943
70KIT0.90163484
71TBK10.89846859
72FGR0.89660634
73STK40.89287337
74MAPK110.88864563
75SGK2230.88861025
76SGK4940.88861025
77DAPK20.87610768
78TEC0.87340403
79RPS6KB20.86241893
80IKBKE0.84107911
81HCK0.83281702
82MST1R0.82312232
83MAP3K70.81685805
84MAP2K40.81591279
85JAK20.78643092
86IRAK10.77532044
87TTK0.75737929
88EPHB10.75042158
89IRAK20.74703457
90IRAK30.73862550
91KSR10.73805110
92TXK0.72430997
93RAF10.72336685
94SGK10.71316605
95CLK10.70196515
96MAP3K50.69549563
97MAP3K130.67503123
98PDGFRB0.67203502
99MTOR0.66997951
100CDC42BPA0.65191973
101HIPK20.64939391
102STK380.63144901
103CDK90.62632751
104MELK0.62512352
105LRRK20.62075123
106PDK10.60733461
107BTK0.60487177
108CSK0.57651949
109STK110.56105185
110MATK0.54966088
111PDPK10.54786321
112ITK0.53102739
113MAPK40.51972667
114PRKAA20.51645988
115ERBB40.50455960
116DMPK0.50052117
117NLK0.49313742
118RPS6KB10.48102684
119EGFR0.46952045
120PRKCQ0.46935147
121MAP3K20.46367257
122LYN0.45885519
123PTK20.45865728
124MAPK100.43704684
125YES10.43091896
126ATR0.42462379
127PLK20.41689614
128TRPM70.40870982
129RET0.40718876
130LCK0.39997314
131ATM0.39597828
132BMX0.37711255
133SYK0.37342697
134CAMK40.36679563
135MAPK10.36465339
136MAPK140.35878137
137MARK30.35773528

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.86315631
2Nitrogen metabolism_Homo sapiens_hsa009103.72302596
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.68245594
4Arginine biosynthesis_Homo sapiens_hsa002203.04184944
5Complement and coagulation cascades_Homo sapiens_hsa046102.97867945
6Staphylococcus aureus infection_Homo sapiens_hsa051502.64333444
7Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.54442487
8Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.47929112
9Bile secretion_Homo sapiens_hsa049761.99912730
10Tryptophan metabolism_Homo sapiens_hsa003801.97173305
11Lysine degradation_Homo sapiens_hsa003101.93358347
12Caffeine metabolism_Homo sapiens_hsa002321.86419216
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.77511502
14ABC transporters_Homo sapiens_hsa020101.66665886
15Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.66120914
16Steroid hormone biosynthesis_Homo sapiens_hsa001401.59400846
17Renal cell carcinoma_Homo sapiens_hsa052111.57861729
18Thyroid cancer_Homo sapiens_hsa052161.55114825
19AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.49670365
20Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.48748582
21Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.46585802
22T cell receptor signaling pathway_Homo sapiens_hsa046601.42725553
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.42201709
24Prolactin signaling pathway_Homo sapiens_hsa049171.40870757
25PPAR signaling pathway_Homo sapiens_hsa033201.40597373
26Fatty acid degradation_Homo sapiens_hsa000711.38396699
27Colorectal cancer_Homo sapiens_hsa052101.34767374
28Neurotrophin signaling pathway_Homo sapiens_hsa047221.31079926
29VEGF signaling pathway_Homo sapiens_hsa043701.26193899
30Viral carcinogenesis_Homo sapiens_hsa052031.26167327
31Inositol phosphate metabolism_Homo sapiens_hsa005621.23826315
32Peroxisome_Homo sapiens_hsa041461.23680909
33One carbon pool by folate_Homo sapiens_hsa006701.19570028
34Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.19268044
35Selenocompound metabolism_Homo sapiens_hsa004501.14684536
36Leukocyte transendothelial migration_Homo sapiens_hsa046701.14047009
37Drug metabolism - other enzymes_Homo sapiens_hsa009831.12615764
38Retinol metabolism_Homo sapiens_hsa008301.11972519
39Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.11713356
40Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09259933
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.08538028
42Chemical carcinogenesis_Homo sapiens_hsa052041.08054499
43Choline metabolism in cancer_Homo sapiens_hsa052311.05563572
44Notch signaling pathway_Homo sapiens_hsa043301.03313179
45Malaria_Homo sapiens_hsa051441.00424271
46NF-kappa B signaling pathway_Homo sapiens_hsa040640.96747042
47Phenylalanine metabolism_Homo sapiens_hsa003600.95298386
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.94915900
49Longevity regulating pathway - mammal_Homo sapiens_hsa042110.94283525
50Bladder cancer_Homo sapiens_hsa052190.94151903
51Focal adhesion_Homo sapiens_hsa045100.94005986
52GnRH signaling pathway_Homo sapiens_hsa049120.93651864
53Phospholipase D signaling pathway_Homo sapiens_hsa040720.93439683
54Chronic myeloid leukemia_Homo sapiens_hsa052200.93047677
55Histidine metabolism_Homo sapiens_hsa003400.88408914
56Amoebiasis_Homo sapiens_hsa051460.87775848
57Insulin signaling pathway_Homo sapiens_hsa049100.87026891
58Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.86971988
59Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.86779260
60Starch and sucrose metabolism_Homo sapiens_hsa005000.85074596
61Sphingolipid signaling pathway_Homo sapiens_hsa040710.83624271
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.82519002
63Other glycan degradation_Homo sapiens_hsa005110.82335988
64Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.81918856
65Tyrosine metabolism_Homo sapiens_hsa003500.81903938
66Legionellosis_Homo sapiens_hsa051340.81521231
67HTLV-I infection_Homo sapiens_hsa051660.81216243
68Central carbon metabolism in cancer_Homo sapiens_hsa052300.81070281
69Primary immunodeficiency_Homo sapiens_hsa053400.80562057
70HIF-1 signaling pathway_Homo sapiens_hsa040660.80210549
71Estrogen signaling pathway_Homo sapiens_hsa049150.78718076
72Fatty acid metabolism_Homo sapiens_hsa012120.78138826
73Leishmaniasis_Homo sapiens_hsa051400.77918789
74Glycosaminoglycan degradation_Homo sapiens_hsa005310.77634728
75Toll-like receptor signaling pathway_Homo sapiens_hsa046200.77405466
76Vitamin digestion and absorption_Homo sapiens_hsa049770.75002577
77Insulin resistance_Homo sapiens_hsa049310.74971852
78RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.74323785
79B cell receptor signaling pathway_Homo sapiens_hsa046620.72685104
80Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.72284295
81Osteoclast differentiation_Homo sapiens_hsa043800.71070430
82Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.70814474
83Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.69700421
84Pathways in cancer_Homo sapiens_hsa052000.69449181
85Long-term potentiation_Homo sapiens_hsa047200.66604235
86beta-Alanine metabolism_Homo sapiens_hsa004100.65953940
87Hematopoietic cell lineage_Homo sapiens_hsa046400.64366139
88Regulation of actin cytoskeleton_Homo sapiens_hsa048100.64358993
89Non-small cell lung cancer_Homo sapiens_hsa052230.64294621
90Shigellosis_Homo sapiens_hsa051310.63859418
91Type II diabetes mellitus_Homo sapiens_hsa049300.63121103
92Toxoplasmosis_Homo sapiens_hsa051450.62974207
93Transcriptional misregulation in cancer_Homo sapiens_hsa052020.62943988
94Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.62217379
95Circadian rhythm_Homo sapiens_hsa047100.62210219
96Alcoholism_Homo sapiens_hsa050340.61825532
97Viral myocarditis_Homo sapiens_hsa054160.61085717
98Cell cycle_Homo sapiens_hsa041100.59803750
99MAPK signaling pathway_Homo sapiens_hsa040100.58718566
100Melanoma_Homo sapiens_hsa052180.58180860
101Endocytosis_Homo sapiens_hsa041440.56279005
102Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.55974948
103MicroRNAs in cancer_Homo sapiens_hsa052060.55508195
104Epstein-Barr virus infection_Homo sapiens_hsa051690.55497351
105Salmonella infection_Homo sapiens_hsa051320.54951194
106Small cell lung cancer_Homo sapiens_hsa052220.54342289
107TNF signaling pathway_Homo sapiens_hsa046680.54316743
108FoxO signaling pathway_Homo sapiens_hsa040680.54310117
109Hepatitis C_Homo sapiens_hsa051600.53700048
110Rap1 signaling pathway_Homo sapiens_hsa040150.52407742
111Dorso-ventral axis formation_Homo sapiens_hsa043200.52189250
112AMPK signaling pathway_Homo sapiens_hsa041520.51253114
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.50781192
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.48987509
115African trypanosomiasis_Homo sapiens_hsa051430.48936638
116Hepatitis B_Homo sapiens_hsa051610.48865179
117Measles_Homo sapiens_hsa051620.48704700
118Butanoate metabolism_Homo sapiens_hsa006500.47367167
119Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.47203477
120Influenza A_Homo sapiens_hsa051640.46378385
121Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44339284
122Glioma_Homo sapiens_hsa052140.44234735
123Adherens junction_Homo sapiens_hsa045200.43399242
124Cysteine and methionine metabolism_Homo sapiens_hsa002700.43095193
125Intestinal immune network for IgA production_Homo sapiens_hsa046720.41005488
126NOD-like receptor signaling pathway_Homo sapiens_hsa046210.40726026
127Herpes simplex infection_Homo sapiens_hsa051680.40582031
128Pancreatic cancer_Homo sapiens_hsa052120.40502155
129Endometrial cancer_Homo sapiens_hsa052130.38731676
130Systemic lupus erythematosus_Homo sapiens_hsa053220.38461495
131Chemokine signaling pathway_Homo sapiens_hsa040620.37903749
132Adipocytokine signaling pathway_Homo sapiens_hsa049200.37351563
133Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36551177
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.36293468
135Proteoglycans in cancer_Homo sapiens_hsa052050.36208859
136Platelet activation_Homo sapiens_hsa046110.35474221
137Acute myeloid leukemia_Homo sapiens_hsa052210.35448762
138Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.35106465
139Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.34832447
140Apoptosis_Homo sapiens_hsa042100.34698510
141Pertussis_Homo sapiens_hsa051330.34279775
142Tuberculosis_Homo sapiens_hsa051520.34269626
143mTOR signaling pathway_Homo sapiens_hsa041500.33720155
144Propanoate metabolism_Homo sapiens_hsa006400.33444425
145Prostate cancer_Homo sapiens_hsa052150.32022389
146Glycerolipid metabolism_Homo sapiens_hsa005610.31675346
1472-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31659005
148Non-homologous end-joining_Homo sapiens_hsa034500.31297828
149Biosynthesis of amino acids_Homo sapiens_hsa012300.31101901
150Thyroid hormone signaling pathway_Homo sapiens_hsa049190.30986117
151Phosphatidylinositol signaling system_Homo sapiens_hsa040700.30838950
152Antigen processing and presentation_Homo sapiens_hsa046120.29280990
153ErbB signaling pathway_Homo sapiens_hsa040120.28501496

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »