RNF182

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)4.70929858
2synapsis (GO:0007129)4.47609336
3regulation of short-term neuronal synaptic plasticity (GO:0048172)4.22839567
4vocalization behavior (GO:0071625)4.20905331
5nucleobase catabolic process (GO:0046113)4.16613865
6G-protein coupled glutamate receptor signaling pathway (GO:0007216)4.12377255
7sensory perception of smell (GO:0007608)4.10151841
8positive regulation of synapse maturation (GO:0090129)4.04012467
9synaptic vesicle docking involved in exocytosis (GO:0016081)3.97459978
10synaptic transmission, glutamatergic (GO:0035249)3.97440150
11glutamate receptor signaling pathway (GO:0007215)3.96366007
12synaptic vesicle exocytosis (GO:0016079)3.90774593
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.88405589
14protein localization to synapse (GO:0035418)3.87361907
15positive regulation of dendritic spine morphogenesis (GO:0061003)3.82883822
16ionotropic glutamate receptor signaling pathway (GO:0035235)3.81807461
17axonal fasciculation (GO:0007413)3.80627712
18positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.80584061
19neuron recognition (GO:0008038)3.79087713
20dendrite morphogenesis (GO:0048813)3.71824130
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)3.69292985
22regulation of chromatin binding (GO:0035561)3.66223952
23regulation of synaptic vesicle exocytosis (GO:2000300)3.63751051
24central nervous system projection neuron axonogenesis (GO:0021952)3.57446360
25postsynaptic membrane organization (GO:0001941)3.56135593
26intraciliary transport (GO:0042073)3.55652281
27neurotransmitter-gated ion channel clustering (GO:0072578)3.48967025
28synapse assembly (GO:0007416)3.47274924
29regulation of synapse maturation (GO:0090128)3.46311036
30regulation of synaptic vesicle transport (GO:1902803)3.45154952
31olfactory bulb development (GO:0021772)3.44333089
32locomotory exploration behavior (GO:0035641)3.44157173
33neuron-neuron synaptic transmission (GO:0007270)3.43723119
34glial cell proliferation (GO:0014009)3.39371572
35regulation of glutamate receptor signaling pathway (GO:1900449)3.37486204
36presynaptic membrane assembly (GO:0097105)3.35912104
37regulation of neuronal synaptic plasticity (GO:0048168)3.34552927
38gamma-aminobutyric acid transport (GO:0015812)3.34099281
39chromosome organization involved in meiosis (GO:0070192)3.32798327
40innervation (GO:0060384)3.26381190
41glutamate secretion (GO:0014047)3.25110635
42axon extension (GO:0048675)3.22661693
43regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.21875495
44synaptic vesicle endocytosis (GO:0048488)3.21626904
45membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.21455843
46male meiosis (GO:0007140)3.21194252
47regulation of synapse structural plasticity (GO:0051823)3.16696897
48microtubule depolymerization (GO:0007019)3.15931568
49central nervous system neuron axonogenesis (GO:0021955)3.15056822
50negative regulation of transcription regulatory region DNA binding (GO:2000678)3.15000755
51dendrite development (GO:0016358)3.13390442
52cerebral cortex radially oriented cell migration (GO:0021799)3.11772960
53cornea development in camera-type eye (GO:0061303)3.11607266
54neural tube formation (GO:0001841)3.11422741
55positive regulation of mitochondrial fission (GO:0090141)3.09573108
56regulation of dendritic spine morphogenesis (GO:0061001)3.09448922
57transmission of nerve impulse (GO:0019226)3.07994937
58regulation of long-term neuronal synaptic plasticity (GO:0048169)3.06282992
59presynaptic membrane organization (GO:0097090)3.05842195
60male meiosis I (GO:0007141)3.05380828
61piRNA metabolic process (GO:0034587)3.04222997
62retinal ganglion cell axon guidance (GO:0031290)3.02290539
63long-term memory (GO:0007616)3.02227724
64detection of calcium ion (GO:0005513)3.01093555
65negative regulation of synaptic transmission, GABAergic (GO:0032229)3.01053996
66cerebellar granule cell differentiation (GO:0021707)3.00670175
67regulation of synaptic plasticity (GO:0048167)3.00608230
68DNA methylation involved in gamete generation (GO:0043046)3.00048568
69gamma-aminobutyric acid signaling pathway (GO:0007214)2.99823712
70protein localization to cilium (GO:0061512)2.99669085
71neuronal ion channel clustering (GO:0045161)2.97801860
72dendritic spine organization (GO:0097061)2.97542423
73response to pheromone (GO:0019236)2.94754419
74proline transport (GO:0015824)2.94610318
75axoneme assembly (GO:0035082)2.93067860
76regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.92748471
77inner ear receptor cell development (GO:0060119)2.92290030
78dendritic spine morphogenesis (GO:0060997)2.91411845
79long-term synaptic potentiation (GO:0060291)2.91249214
80limb bud formation (GO:0060174)2.90606426
81regulation of excitatory postsynaptic membrane potential (GO:0060079)2.90393202
82calcium-mediated signaling using intracellular calcium source (GO:0035584)2.90272570
83cerebellar Purkinje cell differentiation (GO:0021702)2.89130763
84exploration behavior (GO:0035640)2.86887658
85behavioral response to cocaine (GO:0048148)2.86846733
86cilium movement (GO:0003341)2.86529734
87regulation of postsynaptic membrane potential (GO:0060078)2.85905725
88hippocampus development (GO:0021766)2.83999049
89resolution of meiotic recombination intermediates (GO:0000712)2.83739978
90protein K11-linked deubiquitination (GO:0035871)2.83409059
91regulation of vesicle fusion (GO:0031338)2.82862723
92startle response (GO:0001964)2.82732179
93regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.82604275
94pyrimidine nucleobase catabolic process (GO:0006208)2.81771508
95negative regulation of astrocyte differentiation (GO:0048712)2.81166712
96negative regulation of microtubule polymerization (GO:0031115)2.81147434
97regulation of DNA endoreduplication (GO:0032875)2.80912683
98auditory behavior (GO:0031223)2.80631582
99positive regulation of synapse assembly (GO:0051965)2.80342138
100sensory perception of chemical stimulus (GO:0007606)2.79067006
101neuron projection extension (GO:1990138)2.78773134
102behavioral defense response (GO:0002209)2.78524150
103behavioral fear response (GO:0001662)2.78524150
104synaptic vesicle maturation (GO:0016188)2.78096822
105sister chromatid segregation (GO:0000819)2.77899533
106fear response (GO:0042596)2.77399079
107cell communication by electrical coupling (GO:0010644)2.77255052
108calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.76931979
109positive regulation of dendritic spine development (GO:0060999)2.76717846
110negative regulation of dendrite development (GO:2000171)2.76410116
111cell migration in hindbrain (GO:0021535)2.75822274
112establishment of mitochondrion localization (GO:0051654)2.75004393
113regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.73915153
114regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.73459304
115regulation of cilium movement (GO:0003352)2.72443070
116neurotransmitter secretion (GO:0007269)2.71282279
117mitotic sister chromatid segregation (GO:0000070)2.69973882
118response to auditory stimulus (GO:0010996)2.67670080
119layer formation in cerebral cortex (GO:0021819)2.67584025
120regulation of respiratory system process (GO:0044065)2.67035326
121negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.66361637
122long term synaptic depression (GO:0060292)2.66141169
123membrane depolarization during action potential (GO:0086010)2.65870840
124positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.65557403
125reciprocal meiotic recombination (GO:0007131)2.64923858
126reciprocal DNA recombination (GO:0035825)2.64923858
127meiotic cell cycle process (GO:1903046)2.64078817
128synaptonemal complex assembly (GO:0007130)2.63794197
129DNA synthesis involved in DNA repair (GO:0000731)2.63565168
130protein localization to chromosome (GO:0034502)2.56556950
131establishment of nucleus localization (GO:0040023)2.55671357
132meiosis I (GO:0007127)2.55041883
133regulation of dendritic spine development (GO:0060998)2.54928310
134hindbrain development (GO:0030902)2.54775445
135righting reflex (GO:0060013)2.54556166
136negative regulation of axon extension (GO:0030517)2.53540613
137attachment of spindle microtubules to kinetochore (GO:0008608)2.52192746
138ganglion development (GO:0061548)2.50203572
139neuron migration (GO:0001764)2.46018520
140spindle checkpoint (GO:0031577)2.45457842
141meiotic nuclear division (GO:0007126)2.43702572
142negative regulation of axon guidance (GO:1902668)2.42874134
143forebrain neuron differentiation (GO:0021879)2.41365166
144regulation of synapse assembly (GO:0051963)2.37740553
145developmental cell growth (GO:0048588)2.36800604
146mitotic spindle organization (GO:0007052)2.36762782
147metaphase plate congression (GO:0051310)2.35509785
148mitotic spindle assembly checkpoint (GO:0007094)2.34298750
149synaptonemal complex organization (GO:0070193)2.33814407
150spinal cord development (GO:0021510)2.33783746
151regulation of spindle organization (GO:0090224)2.33575773
152axonogenesis (GO:0007409)2.33469805
153microtubule polymerization or depolymerization (GO:0031109)2.33256572
154microtubule anchoring (GO:0034453)2.33060283
155regulation of axon guidance (GO:1902667)2.32613639
156striatum development (GO:0021756)2.32517234
157mitotic metaphase plate congression (GO:0007080)2.32317689
158synapse organization (GO:0050808)2.31670426
159mitotic spindle checkpoint (GO:0071174)2.31254555
160retina layer formation (GO:0010842)2.31212366
161regulation of collateral sprouting (GO:0048670)2.30985506
162cerebral cortex cell migration (GO:0021795)2.30221852
163spindle assembly checkpoint (GO:0071173)2.29988610

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.07908005
2SALL1_21062744_ChIP-ChIP_HESCs_Human3.58627055
3GBX2_23144817_ChIP-Seq_PC3_Human3.44616513
4FOXM1_23109430_ChIP-Seq_U2OS_Human2.96722010
5TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.85149586
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.73767344
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.71638142
8SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.70377395
9ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.59965895
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.56157243
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.56157243
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.55150984
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.54204566
14EED_16625203_ChIP-ChIP_MESCs_Mouse2.50804856
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.46312143
16SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.41613011
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.39798641
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.30098175
19SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.26407508
20REST_21632747_ChIP-Seq_MESCs_Mouse2.24493199
21RNF2_27304074_Chip-Seq_ESCs_Mouse2.14862533
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.13582167
23* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.11382379
24MTF2_20144788_ChIP-Seq_MESCs_Mouse2.07626297
25DROSHA_22980978_ChIP-Seq_HELA_Human1.99318563
26* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.93902375
27BMI1_23680149_ChIP-Seq_NPCS_Mouse1.92721467
28E2F7_22180533_ChIP-Seq_HELA_Human1.90227595
29E2F4_17652178_ChIP-ChIP_JURKAT_Human1.88234969
30EWS_26573619_Chip-Seq_HEK293_Human1.85984024
31PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.84880635
32CTBP1_25329375_ChIP-Seq_LNCAP_Human1.84124782
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.83698730
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.82977557
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.82465106
36CBX2_27304074_Chip-Seq_ESCs_Mouse1.78420635
37RARB_27405468_Chip-Seq_BRAIN_Mouse1.73868845
38IGF1R_20145208_ChIP-Seq_DFB_Human1.72973263
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72367639
40PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.69195971
41RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.67887208
42SMAD4_21799915_ChIP-Seq_A2780_Human1.66809868
43REST_18959480_ChIP-ChIP_MESCs_Mouse1.65792005
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.63834445
45SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.63459357
46GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.61571304
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.59455456
48P300_19829295_ChIP-Seq_ESCs_Human1.58734123
49TAF15_26573619_Chip-Seq_HEK293_Human1.56238554
50ZNF274_21170338_ChIP-Seq_K562_Hela1.55220362
51RNF2_27304074_Chip-Seq_NSC_Mouse1.53314310
52VDR_22108803_ChIP-Seq_LS180_Human1.53079510
53POU5F1_16153702_ChIP-ChIP_HESCs_Human1.52328975
54IKZF1_21737484_ChIP-ChIP_HCT116_Human1.48878521
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.48070958
56KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.45962363
57PIAS1_25552417_ChIP-Seq_VCAP_Human1.42473830
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.40510747
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.37990741
60KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.36070082
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35961030
62* RING1B_27294783_Chip-Seq_ESCs_Mouse1.34062946
63SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33711905
64CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29661511
65CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.28470189
66* ARNT_22903824_ChIP-Seq_MCF-7_Human1.27923035
67OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.27319468
68WT1_19549856_ChIP-ChIP_CCG9911_Human1.26884504
69SMAD_19615063_ChIP-ChIP_OVARY_Human1.26506404
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.25913085
71* AHR_22903824_ChIP-Seq_MCF-7_Human1.25766634
72HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.25045722
73TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.23086466
74STAT3_23295773_ChIP-Seq_U87_Human1.22858858
75NR3C1_21868756_ChIP-Seq_MCF10A_Human1.22515884
76RUNX2_22187159_ChIP-Seq_PCA_Human1.22207177
77FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.21633595
78NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20492003
79ZNF217_24962896_ChIP-Seq_MCF-7_Human1.19397212
80TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19103913
81POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.19103913
82TP53_16413492_ChIP-PET_HCT116_Human1.18565031
83AR_25329375_ChIP-Seq_VCAP_Human1.18247520
84SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18194995
85SOX2_21211035_ChIP-Seq_LN229_Gbm1.17453565
86AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17432424
87MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.17367343
88AR_21572438_ChIP-Seq_LNCaP_Human1.16255358
89STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.15023856
90* TP53_18474530_ChIP-ChIP_U2OS_Human1.14758533
91ERG_21242973_ChIP-ChIP_JURKAT_Human1.14691588
92GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13603177
93ER_23166858_ChIP-Seq_MCF-7_Human1.12734322
94BCAT_22108803_ChIP-Seq_LS180_Human1.12679522
95AR_19668381_ChIP-Seq_PC3_Human1.11311017
96TCF4_23295773_ChIP-Seq_U87_Human1.11160155
97TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11152819
98TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10741129
99FUS_26573619_Chip-Seq_HEK293_Human1.10308966
100PRDM14_20953172_ChIP-Seq_ESCs_Human1.07133258
101YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06685513
102NANOG_18555785_Chip-Seq_ESCs_Mouse1.05200050
103MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.04513433
104MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.04226196
105* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03804424
106TBX3_20139965_ChIP-Seq_MESCs_Mouse1.03198943
107TBX3_20139965_ChIP-Seq_ESCs_Mouse1.02657796
108RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.98827109
109TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.98706182
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.97837647
111SOX2_16153702_ChIP-ChIP_HESCs_Human0.96700083
112VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.96031433
113EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95565441
114TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.94799105
115JUN_21703547_ChIP-Seq_K562_Human0.94116899
116* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.94085127
117SMAD3_21741376_ChIP-Seq_ESCs_Human0.91672782
118PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90893089
119FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.90382899
120CBP_20019798_ChIP-Seq_JUKART_Human0.90078252
121IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.90078252
122* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.89887330
123SOX9_26525672_Chip-Seq_HEART_Mouse0.89771177
124E2F1_18555785_Chip-Seq_ESCs_Mouse0.89321694
125LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88840924
126SMAD4_21741376_ChIP-Seq_HESCs_Human0.88553022
127SMAD4_21741376_ChIP-Seq_EPCs_Human0.87416692

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity4.60479819
2MP0003880_abnormal_central_pattern3.54700881
3MP0001984_abnormal_olfaction3.44978031
4MP0003787_abnormal_imprinting3.23493980
5MP0008789_abnormal_olfactory_epithelium3.21322960
6MP0003635_abnormal_synaptic_transmissio3.06712906
7MP0004270_analgesia3.00989466
8MP0005394_taste/olfaction_phenotype2.99096570
9MP0005499_abnormal_olfactory_system2.99096570
10MP0005645_abnormal_hypothalamus_physiol2.78976086
11MP0002063_abnormal_learning/memory/cond2.58699113
12MP0000778_abnormal_nervous_system2.52013694
13MP0000569_abnormal_digit_pigmentation2.45445279
14MP0009745_abnormal_behavioral_response2.43402002
15MP0002184_abnormal_innervation2.31844912
16MP0002734_abnormal_mechanical_nocicepti2.29745777
17MP0002572_abnormal_emotion/affect_behav2.19343259
18MP0001968_abnormal_touch/_nociception2.17600889
19MP0002736_abnormal_nociception_after2.15079584
20MP0001486_abnormal_startle_reflex2.13576449
21MP0002064_seizures2.04434200
22MP0002272_abnormal_nervous_system1.99398794
23MP0006276_abnormal_autonomic_nervous1.98230563
24MP0001485_abnormal_pinna_reflex1.96621179
25MP0002735_abnormal_chemical_nociception1.92011287
26MP0001188_hyperpigmentation1.91674220
27MP0002557_abnormal_social/conspecific_i1.83323054
28MP0005646_abnormal_pituitary_gland1.83072164
29MP0005423_abnormal_somatic_nervous1.77797050
30MP0001440_abnormal_grooming_behavior1.76761514
31MP0004885_abnormal_endolymph1.76428850
32MP0002067_abnormal_sensory_capabilities1.72102445
33MP0002638_abnormal_pupillary_reflex1.71775309
34MP0006292_abnormal_olfactory_placode1.69719748
35MP0001529_abnormal_vocalization1.65047662
36MP0004858_abnormal_nervous_system1.62249781
37MP0001502_abnormal_circadian_rhythm1.61486219
38MP0008058_abnormal_DNA_repair1.59397610
39MP0003890_abnormal_embryonic-extraembry1.53220848
40MP0009046_muscle_twitch1.50749457
41MP0002882_abnormal_neuron_morphology1.49283357
42MP0005187_abnormal_penis_morphology1.48707739
43MP0001970_abnormal_pain_threshold1.48478617
44MP0002733_abnormal_thermal_nociception1.47905141
45MP0002653_abnormal_ependyma_morphology1.46340618
46MP0002102_abnormal_ear_morphology1.44994043
47MP0003136_yellow_coat_color1.43872853
48MP0001501_abnormal_sleep_pattern1.40977844
49MP0008057_abnormal_DNA_replication1.40720233
50MP0003937_abnormal_limbs/digits/tail_de1.40320076
51MP0005171_absent_coat_pigmentation1.37687775
52MP0008569_lethality_at_weaning1.36184545
53MP0000955_abnormal_spinal_cord1.32519167
54MP0004742_abnormal_vestibular_system1.32241381
55MP0004811_abnormal_neuron_physiology1.30817234
56MP0002152_abnormal_brain_morphology1.26494771
57MP0009780_abnormal_chondrocyte_physiolo1.26135972
58MP0002234_abnormal_pharynx_morphology1.25808776
59MP0002210_abnormal_sex_determination1.25621392
60MP0003119_abnormal_digestive_system1.21097937
61MP0000372_irregular_coat_pigmentation1.21038703
62MP0005377_hearing/vestibular/ear_phenot1.20732546
63MP0003878_abnormal_ear_physiology1.20732546
64MP0008877_abnormal_DNA_methylation1.19867699
65MP0000049_abnormal_middle_ear1.19856203
66MP0002909_abnormal_adrenal_gland1.19391183
67MP0000026_abnormal_inner_ear1.18369623
68MP0000647_abnormal_sebaceous_gland1.17599208
69MP0010094_abnormal_chromosome_stability1.17404062
70MP0001963_abnormal_hearing_physiology1.16878718
71MP0002752_abnormal_somatic_nervous1.15328883
72MP0010030_abnormal_orbit_morphology1.14661569
73MP0000631_abnormal_neuroendocrine_gland1.13875647
74MP0003879_abnormal_hair_cell1.13247977
75MP0005551_abnormal_eye_electrophysiolog1.12332460
76MP0003718_maternal_effect1.12149361
77MP0003693_abnormal_embryo_hatching1.10948859
78MP0003938_abnormal_ear_development1.09560335
79MP0001299_abnormal_eye_distance/1.08889324
80MP0005623_abnormal_meninges_morphology1.07193449
81MP0006072_abnormal_retinal_apoptosis1.07030513
82MP0004142_abnormal_muscle_tone1.06463994
83MP0003861_abnormal_nervous_system1.04983834
84MP0002751_abnormal_autonomic_nervous1.04649818
85MP0001286_abnormal_eye_development1.03860286
86MP0002066_abnormal_motor_capabilities/c1.03499300
87MP0001905_abnormal_dopamine_level1.01752280
88MP0003698_abnormal_male_reproductive1.01598451
89MP0004147_increased_porphyrin_level1.00890814
90MP0000579_abnormal_nail_morphology0.99701056
91MP0002233_abnormal_nose_morphology0.98188329
92MP0001929_abnormal_gametogenesis0.97327205
93MP0003111_abnormal_nucleus_morphology0.97223461
94MP0003077_abnormal_cell_cycle0.95672308
95MP0008932_abnormal_embryonic_tissue0.95665763
96MP0005386_behavior/neurological_phenoty0.94216798
97MP0004924_abnormal_behavior0.94216798
98MP0005391_vision/eye_phenotype0.94008832
99MP0003385_abnormal_body_wall0.93022905
100MP0000534_abnormal_ureter_morphology0.92702077
101MP0004133_heterotaxia0.92639934
102MP0004043_abnormal_pH_regulation0.91336906
103MP0000653_abnormal_sex_gland0.89909420
104MP0002822_catalepsy0.89645272
105MP0003121_genomic_imprinting0.89583629
106MP0010386_abnormal_urinary_bladder0.89386807
107MP0001145_abnormal_male_reproductive0.87856596
108MP0001293_anophthalmia0.87820441
109MP0002081_perinatal_lethality0.85827472
110MP0002697_abnormal_eye_size0.85515103
111MP0002876_abnormal_thyroid_physiology0.85060602
112MP0003935_abnormal_craniofacial_develop0.84794800
113MP0000678_abnormal_parathyroid_gland0.83996868
114MP0003942_abnormal_urinary_system0.82327925
115MP0003123_paternal_imprinting0.81095782
116MP0002160_abnormal_reproductive_system0.80841867
117MP0003634_abnormal_glial_cell0.80788461
118MP0009703_decreased_birth_body0.80128552
119MP0002229_neurodegeneration0.77903082
120MP0003633_abnormal_nervous_system0.77602122
121MP0002249_abnormal_larynx_morphology0.77061406
122MP0003755_abnormal_palate_morphology0.76764627
123MP0002069_abnormal_eating/drinking_beha0.74684071
124MP0003329_amyloid_beta_deposits0.74572946
125MP0004134_abnormal_chest_morphology0.74346215
126MP0003137_abnormal_impulse_conducting0.73557075
127MP0002837_dystrophic_cardiac_calcinosis0.72142661
128MP0002116_abnormal_craniofacial_bone0.69870446
129MP0003631_nervous_system_phenotype0.68922841
130MP0009250_abnormal_appendicular_skeleto0.67233166
131MP0004085_abnormal_heartbeat0.66286585
132MP0004145_abnormal_muscle_electrophysio0.65149965
133MP0001177_atelectasis0.64751258
134MP0003122_maternal_imprinting0.63250715
135MP0005253_abnormal_eye_physiology0.62714508
136MP0003283_abnormal_digestive_organ0.60002192
137MP0005409_darkened_coat_color0.59774292

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)4.94458693
2Volvulus (HP:0002580)4.53878835
3Febrile seizures (HP:0002373)4.30019316
4Atonic seizures (HP:0010819)3.89016438
5Progressive cerebellar ataxia (HP:0002073)3.79682836
6Abnormal ciliary motility (HP:0012262)3.77189421
7Abnormal respiratory motile cilium physiology (HP:0012261)3.76506028
8Epileptic encephalopathy (HP:0200134)3.62454954
9Gait imbalance (HP:0002141)3.58395993
10Medial flaring of the eyebrow (HP:0010747)3.57362239
11Myokymia (HP:0002411)3.46005028
12Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.42479298
13Focal seizures (HP:0007359)3.41068827
14Cortical dysplasia (HP:0002539)3.39709893
15Pancreatic fibrosis (HP:0100732)3.36786822
16Hyperventilation (HP:0002883)3.32896474
17Visual hallucinations (HP:0002367)3.28284065
18Congenital primary aphakia (HP:0007707)3.25695135
19Abnormality of the labia minora (HP:0012880)3.17994272
20Decreased circulating renin level (HP:0003351)3.08880066
21Anosmia (HP:0000458)3.07656861
22Nephrogenic diabetes insipidus (HP:0009806)3.07393897
23Abnormality of the lower motor neuron (HP:0002366)3.05702242
24Abnormal respiratory epithelium morphology (HP:0012253)2.99001607
25Abnormal respiratory motile cilium morphology (HP:0005938)2.99001607
26Absence seizures (HP:0002121)2.87021878
27Rhinitis (HP:0012384)2.84193967
28Abnormality of the corticospinal tract (HP:0002492)2.78796217
29Genetic anticipation (HP:0003743)2.67976181
30Increased nuchal translucency (HP:0010880)2.65514809
31Amblyopia (HP:0000646)2.64800100
32Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.64568879
33Degeneration of the lateral corticospinal tracts (HP:0002314)2.64568879
34Poor coordination (HP:0002370)2.61752006
35Genital tract atresia (HP:0001827)2.61480005
36True hermaphroditism (HP:0010459)2.59243769
37Hypothermia (HP:0002045)2.58221227
38Dialeptic seizures (HP:0011146)2.57239403
39Median cleft lip (HP:0000161)2.54123838
40Shoulder girdle muscle weakness (HP:0003547)2.52177442
41Generalized tonic-clonic seizures (HP:0002069)2.50948882
42Vaginal atresia (HP:0000148)2.49657388
43Broad-based gait (HP:0002136)2.48208573
44Postaxial hand polydactyly (HP:0001162)2.48154913
45Abnormality of midbrain morphology (HP:0002418)2.48148463
46Molar tooth sign on MRI (HP:0002419)2.48148463
47Aplasia/Hypoplasia of the sternum (HP:0006714)2.47490836
48Action tremor (HP:0002345)2.44705671
49Nephronophthisis (HP:0000090)2.40650080
50Oligodactyly (HP:0012165)2.40205291
51Lissencephaly (HP:0001339)2.35941814
52Drooling (HP:0002307)2.35539657
53Excessive salivation (HP:0003781)2.35539657
54Limb dystonia (HP:0002451)2.27723605
55Palpebral edema (HP:0100540)2.24779314
56Megalencephaly (HP:0001355)2.24478513
57Epileptiform EEG discharges (HP:0011182)2.24457569
58Aplasia/Hypoplasia of the lens (HP:0008063)2.23639592
59Gaze-evoked nystagmus (HP:0000640)2.20532798
60Retinal dysplasia (HP:0007973)2.16701556
61Chronic hepatic failure (HP:0100626)2.15597570
62Papillary thyroid carcinoma (HP:0002895)2.15140893
63Amyotrophic lateral sclerosis (HP:0007354)2.13173384
64Bifid tongue (HP:0010297)2.12790922
65Supranuclear gaze palsy (HP:0000605)2.11578195
66Hyperactive renin-angiotensin system (HP:0000841)2.10903748
67Pelvic girdle muscle weakness (HP:0003749)2.10395418
68Gastroesophageal reflux (HP:0002020)2.09648704
69Aplasia involving bones of the extremities (HP:0009825)2.08529685
70Aplasia involving bones of the upper limbs (HP:0009823)2.08529685
71Aplasia of the phalanges of the hand (HP:0009802)2.08529685
72Congenital hepatic fibrosis (HP:0002612)2.05333397
73Increased circulating renin level (HP:0000848)2.04632909
74Absent eyebrow (HP:0002223)2.04115010
75Truncal ataxia (HP:0002078)2.03977186
76Protruding tongue (HP:0010808)2.03765660
77Absent speech (HP:0001344)2.01334754
78Large earlobe (HP:0009748)2.00743327
79Hyperaldosteronism (HP:0000859)2.00462675
80Limb-girdle muscle weakness (HP:0003325)2.00239076
81Abnormality of the hip-girdle musculature (HP:0001445)1.99505172
82Abnormality of the musculature of the pelvis (HP:0001469)1.99505172
83Abnormality of hair growth rate (HP:0011363)1.96984015
84Slow-growing hair (HP:0002217)1.96984015
85Hypoplasia of the brainstem (HP:0002365)1.96654764
86Aplasia/Hypoplasia of the brainstem (HP:0007362)1.96654764
87Thickened helices (HP:0000391)1.95832780
88EEG with generalized epileptiform discharges (HP:0011198)1.95500920
89Abnormality of the renal medulla (HP:0100957)1.94786963
90Tubulointerstitial nephritis (HP:0001970)1.94638665
91Impaired smooth pursuit (HP:0007772)1.93289046
92Hemiparesis (HP:0001269)1.92732213
93Dysmetria (HP:0001310)1.91992404
94Occipital encephalocele (HP:0002085)1.91668053
95Dysdiadochokinesis (HP:0002075)1.90678679
96Impaired vibration sensation in the lower limbs (HP:0002166)1.90087833
97Specific learning disability (HP:0001328)1.88464389
98Abnormality of salivation (HP:0100755)1.88343619
99Urinary urgency (HP:0000012)1.88258177
100Postaxial foot polydactyly (HP:0001830)1.87000398
101Dynein arm defect of respiratory motile cilia (HP:0012255)1.86521182
102Absent/shortened dynein arms (HP:0200106)1.86521182
103Pachygyria (HP:0001302)1.84906913
104Spastic gait (HP:0002064)1.83590838
105Agitation (HP:0000713)1.83459288
106Cutaneous finger syndactyly (HP:0010554)1.83244941
107Ankle clonus (HP:0011448)1.83220089
108Omphalocele (HP:0001539)1.82793194
109Hypsarrhythmia (HP:0002521)1.81778311
110Pancreatic cysts (HP:0001737)1.80715989
111Intellectual disability, moderate (HP:0002342)1.78853751
112Facial cleft (HP:0002006)1.78744705
113Abnormal lung lobation (HP:0002101)1.78497987
114Cutaneous syndactyly (HP:0012725)1.78487699
115Vertebral arch anomaly (HP:0008438)1.78284309
116Sclerocornea (HP:0000647)1.78173670
117Preaxial hand polydactyly (HP:0001177)1.76870913
118Split foot (HP:0001839)1.75614534
119Abnormality of binocular vision (HP:0011514)1.75345138
120Diplopia (HP:0000651)1.75345138
121Blue irides (HP:0000635)1.74926979
122Oligodactyly (hands) (HP:0001180)1.74816047
123Bradycardia (HP:0001662)1.74504320
124Choroideremia (HP:0001139)1.74051531
125Micropenis (HP:0000054)1.73946844
126Obsessive-compulsive behavior (HP:0000722)1.73942038
127Anxiety (HP:0000739)1.73693020
128Mask-like facies (HP:0000298)1.73354503
129Chronic bronchitis (HP:0004469)1.72333811
130Impaired social interactions (HP:0000735)1.72240030
131Abnormal social behavior (HP:0012433)1.72240030
132Ectopic kidney (HP:0000086)1.72234666
133Exotropia (HP:0000577)1.70002167
134Heterotopia (HP:0002282)1.69087316
135Poor eye contact (HP:0000817)1.68630222
136Truncal obesity (HP:0001956)1.65861798
137Patellar aplasia (HP:0006443)1.65342109
138Urinary bladder sphincter dysfunction (HP:0002839)1.63850439
139Highly arched eyebrow (HP:0002553)1.63003289
140Optic nerve hypoplasia (HP:0000609)1.62462417
141Aplasia/Hypoplasia of the tongue (HP:0010295)1.61880481
142High anterior hairline (HP:0009890)1.60976208
143Hypoplastic iliac wings (HP:0002866)1.60711755
144Broad foot (HP:0001769)1.59858458
145Pendular nystagmus (HP:0012043)1.59341153
146Narrow forehead (HP:0000341)1.56067730
147Facial hemangioma (HP:0000329)1.55885808
148Birth length less than 3rd percentile (HP:0003561)1.55458402
149Rimmed vacuoles (HP:0003805)1.53335948
150Renal hypoplasia (HP:0000089)1.51003667
151Termporal pattern (HP:0011008)1.50551668
152Insidious onset (HP:0003587)1.50551668
153Inappropriate behavior (HP:0000719)1.50177429
154Abnormality of chromosome segregation (HP:0002916)1.50026360
155Fibular hypoplasia (HP:0003038)1.48891407

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB34.49519870
2BMPR23.89748203
3EPHA43.55546882
4NTRK33.43935027
5CASK3.28914534
6MARK13.22257480
7NTRK23.06593244
8MAP2K72.85867736
9MAPK132.68434590
10MAP3K42.44369827
11PLK22.24571809
12BUB12.13357627
13MINK11.94050528
14SIK31.81785468
15WEE11.80339787
16TNIK1.73802924
17SIK21.72844719
18SRPK11.69834504
19PRPF4B1.66001847
20CCNB11.64648629
21DYRK1A1.62403624
22AKT31.61322642
23TTK1.55571222
24DAPK21.48881031
25CAMK2B1.44931431
26CSNK1G21.43494218
27SGK21.42704367
28STK38L1.40942822
29PHKG11.37277222
30PHKG21.37277222
31MKNK11.36320361
32CAMK1G1.35598596
33PLK41.35164439
34PRKCG1.31694241
35MAP3K91.28534863
36MARK21.28253438
37CDC71.25918426
38INSRR1.24987535
39SGK4941.23028989
40SGK2231.23028989
41MAP2K41.22129458
42TRIM281.15101797
43MET1.14331241
44DYRK21.14264631
45MAP3K61.12673160
46MAP4K21.08572470
47PLK11.07800852
48KSR11.06909334
49CDK51.06417173
50PNCK1.04121843
51MAPK151.03940799
52BRSK21.03714588
53DYRK31.00616471
54CAMK2A0.98165748
55CDK190.96142323
56BRSK10.95665212
57PRKD30.94857830
58RPS6KA40.93658173
59CAMK2D0.92897930
60UHMK10.91470842
61CAMKK20.91452368
62BRAF0.90086691
63TSSK60.89627454
64NEK10.88156370
65TYRO30.84681808
66CDK30.83646387
67GRK50.78895504
68SGK30.77522698
69NEK20.76928485
70PAK60.74896583
71PRKCE0.74693290
72DAPK10.74334842
73PINK10.72653541
74EIF2AK10.71004536
75FGFR20.69439304
76PBK0.65898828
77YES10.65169684
78PDK20.65077559
79CAMK2G0.64186280
80NUAK10.61515594
81PKN10.59266265
82PAK30.59106767
83STK30.58838635
84SGK10.58316807
85CSNK1A1L0.57089163
86CHEK20.55481651
87EPHA30.54933214
88CDC42BPA0.54922272
89ERBB40.53781644
90ATR0.53309116
91CDK180.52885100
92ARAF0.51684142
93RPS6KB10.51193073
94CSNK1G30.50180781
95MKNK20.50094253
96ZAK0.49959162
97CDK150.47590985
98MAP3K120.47139085
99GRK70.46822469
100AURKA0.46271931
101CSNK1G10.46202788
102FES0.46164889
103BRD40.44764882
104CDK10.44686633
105ATM0.44566047
106LMTK20.44090854
107FGR0.43379361
108CDK140.43351791
109HIPK20.43137837
110FER0.42541154
111BMPR1B0.42495141
112EPHB20.41962727
113CHEK10.41788486
114STK160.41506013
115RIPK10.41036829
116BCR0.40889430
117CDK11A0.39976885
118RAF10.39675425
119PRKCZ0.39342175
120DMPK0.39253713
121PLK30.38942080
122MAP3K50.38393405
123CSNK1E0.37886413
124CAMKK10.37297525
125PRKACA0.36339991
126ERBB20.35990508
127WNK30.35834329
128STK380.35759997
129ROCK20.35727993
130RIPK40.35439194
131NME10.34532753
132RPS6KA20.34366931
133PRKCH0.34227369
134PRKCI0.33949650
135ADRBK10.33872797
136PTK2B0.33156878
137PRKG10.31443185
138MAP3K20.30942798
139CAMK40.30512594
140NTRK10.29768142
141CSNK1A10.29224825
142MAPK80.28769958

Predicted pathways (KEGG)

RankGene SetZ-score
1Olfactory transduction_Homo sapiens_hsa047404.05488588
2Nicotine addiction_Homo sapiens_hsa050333.88585587
3Circadian entrainment_Homo sapiens_hsa047132.89186607
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.82100866
5Glutamatergic synapse_Homo sapiens_hsa047242.77633773
6Long-term potentiation_Homo sapiens_hsa047202.57531039
7Synaptic vesicle cycle_Homo sapiens_hsa047212.55240703
8Morphine addiction_Homo sapiens_hsa050322.54980538
9GABAergic synapse_Homo sapiens_hsa047272.51981870
10Taste transduction_Homo sapiens_hsa047422.47939632
11Amphetamine addiction_Homo sapiens_hsa050312.46926427
12Insulin secretion_Homo sapiens_hsa049112.46015655
13Dopaminergic synapse_Homo sapiens_hsa047282.26996283
14Serotonergic synapse_Homo sapiens_hsa047262.02573366
15Cell cycle_Homo sapiens_hsa041101.95113616
16Non-homologous end-joining_Homo sapiens_hsa034501.92013642
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.90431443
18Cholinergic synapse_Homo sapiens_hsa047251.89262044
19Salivary secretion_Homo sapiens_hsa049701.83064041
20Aldosterone synthesis and secretion_Homo sapiens_hsa049251.70268449
21Steroid biosynthesis_Homo sapiens_hsa001001.67732868
22Long-term depression_Homo sapiens_hsa047301.63864233
23Cocaine addiction_Homo sapiens_hsa050301.59849593
24Fanconi anemia pathway_Homo sapiens_hsa034601.52218423
25Gastric acid secretion_Homo sapiens_hsa049711.52100931
26Phototransduction_Homo sapiens_hsa047441.50609917
27Calcium signaling pathway_Homo sapiens_hsa040201.50559498
28Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.46416983
29Basal transcription factors_Homo sapiens_hsa030221.44210634
30Axon guidance_Homo sapiens_hsa043601.42572571
31Collecting duct acid secretion_Homo sapiens_hsa049661.39781824
32cAMP signaling pathway_Homo sapiens_hsa040241.36455183
33Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.28986693
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28033235
35Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.26863673
36Renin secretion_Homo sapiens_hsa049241.24651746
37Mismatch repair_Homo sapiens_hsa034301.23618980
38Vibrio cholerae infection_Homo sapiens_hsa051101.23364991
39GnRH signaling pathway_Homo sapiens_hsa049121.23288739
40Oxytocin signaling pathway_Homo sapiens_hsa049211.22707249
41Melanogenesis_Homo sapiens_hsa049161.19910503
42Hippo signaling pathway_Homo sapiens_hsa043901.16875003
43Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.15624431
44RNA transport_Homo sapiens_hsa030131.14443201
45Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.13976409
46Gap junction_Homo sapiens_hsa045401.08694253
47DNA replication_Homo sapiens_hsa030301.08289652
48Type II diabetes mellitus_Homo sapiens_hsa049301.08203355
49Homologous recombination_Homo sapiens_hsa034401.06679039
50RNA degradation_Homo sapiens_hsa030181.05192984
51cGMP-PKG signaling pathway_Homo sapiens_hsa040221.04679806
52Phosphatidylinositol signaling system_Homo sapiens_hsa040701.04664378
53Circadian rhythm_Homo sapiens_hsa047101.03718240
54mRNA surveillance pathway_Homo sapiens_hsa030151.03472299
55Maturity onset diabetes of the young_Homo sapiens_hsa049501.00009184
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.99707145
57Base excision repair_Homo sapiens_hsa034100.98421126
58Estrogen signaling pathway_Homo sapiens_hsa049150.96301462
59ErbB signaling pathway_Homo sapiens_hsa040120.96239604
60Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.95800035
61Nucleotide excision repair_Homo sapiens_hsa034200.94134097
62Glioma_Homo sapiens_hsa052140.92624152
63Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.89963911
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.88303151
65Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.86328237
66Thyroid hormone synthesis_Homo sapiens_hsa049180.83201224
67Pyruvate metabolism_Homo sapiens_hsa006200.82209088
68Wnt signaling pathway_Homo sapiens_hsa043100.81803223
69Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.79886041
70Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.79430757
71Alcoholism_Homo sapiens_hsa050340.78155816
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.77120646
73Pancreatic secretion_Homo sapiens_hsa049720.75070691
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.74739802
75Vascular smooth muscle contraction_Homo sapiens_hsa042700.73578951
76Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.72153792
77Glucagon signaling pathway_Homo sapiens_hsa049220.70674372
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.70177007
79Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.69961598
80Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.69613397
81Neurotrophin signaling pathway_Homo sapiens_hsa047220.68626184
82Ras signaling pathway_Homo sapiens_hsa040140.68193123
83Spliceosome_Homo sapiens_hsa030400.67209612
84Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.66429218
85Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65946949
86Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65882398
87MAPK signaling pathway_Homo sapiens_hsa040100.64898092
88Parkinsons disease_Homo sapiens_hsa050120.64496861
89Propanoate metabolism_Homo sapiens_hsa006400.64315377
90Alzheimers disease_Homo sapiens_hsa050100.60657103
91Oocyte meiosis_Homo sapiens_hsa041140.58903519
92Choline metabolism in cancer_Homo sapiens_hsa052310.58437096
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.57585561
94Lysine degradation_Homo sapiens_hsa003100.57168229
95TGF-beta signaling pathway_Homo sapiens_hsa043500.56762880
96Cardiac muscle contraction_Homo sapiens_hsa042600.56720197
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55846320
98SNARE interactions in vesicular transport_Homo sapiens_hsa041300.55744854
99MicroRNAs in cancer_Homo sapiens_hsa052060.55716813
100Nitrogen metabolism_Homo sapiens_hsa009100.55306964
101Adherens junction_Homo sapiens_hsa045200.54612498
102Ovarian steroidogenesis_Homo sapiens_hsa049130.52549729
103Hedgehog signaling pathway_Homo sapiens_hsa043400.51799866
104Colorectal cancer_Homo sapiens_hsa052100.50382647
105Endometrial cancer_Homo sapiens_hsa052130.47986756
106Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47575010
107beta-Alanine metabolism_Homo sapiens_hsa004100.47196599
108Phospholipase D signaling pathway_Homo sapiens_hsa040720.46540805
109Rap1 signaling pathway_Homo sapiens_hsa040150.46268588
110Folate biosynthesis_Homo sapiens_hsa007900.46225194
111Butanoate metabolism_Homo sapiens_hsa006500.45389931
112Dilated cardiomyopathy_Homo sapiens_hsa054140.44172629
113Fatty acid biosynthesis_Homo sapiens_hsa000610.43982506
114p53 signaling pathway_Homo sapiens_hsa041150.43871132
115Cysteine and methionine metabolism_Homo sapiens_hsa002700.43316230
116Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.43133567
117Ether lipid metabolism_Homo sapiens_hsa005650.43091534
118Sphingolipid metabolism_Homo sapiens_hsa006000.42565680
119Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.42199234
120Inositol phosphate metabolism_Homo sapiens_hsa005620.41644688
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.40622654
122Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.39917942
123AMPK signaling pathway_Homo sapiens_hsa041520.38833838
124Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.38133803
125Huntingtons disease_Homo sapiens_hsa050160.38027629
126Protein export_Homo sapiens_hsa030600.37784175
127Dorso-ventral axis formation_Homo sapiens_hsa043200.35787027
128Regulation of autophagy_Homo sapiens_hsa041400.35524928
129FoxO signaling pathway_Homo sapiens_hsa040680.34862008
130Longevity regulating pathway - mammal_Homo sapiens_hsa042110.33941821
131Oxidative phosphorylation_Homo sapiens_hsa001900.33225483
132VEGF signaling pathway_Homo sapiens_hsa043700.32208470
133Basal cell carcinoma_Homo sapiens_hsa052170.31909795
134Melanoma_Homo sapiens_hsa052180.26083196
135Insulin signaling pathway_Homo sapiens_hsa049100.25318726
136Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.25059634
137Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.24658748

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