Rank | Gene Set | Z-score |
---|---|---|
1 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 6.20970791 |
2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.04991762 |
3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.94237753 |
4 | ATP synthesis coupled proton transport (GO:0015986) | 5.94237753 |
5 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 5.24268492 |
6 | respiratory electron transport chain (GO:0022904) | 5.16657397 |
7 | sarcomere organization (GO:0045214) | 5.04481462 |
8 | electron transport chain (GO:0022900) | 5.02042160 |
9 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 4.79185360 |
10 | cardiac myofibril assembly (GO:0055003) | 4.78725989 |
11 | regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 4.60649859 |
12 | cellular ketone body metabolic process (GO:0046950) | 4.57308872 |
13 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 4.52316693 |
14 | myofibril assembly (GO:0030239) | 4.43797207 |
15 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 4.36891357 |
16 | negative regulation of protein localization to cell surface (GO:2000009) | 4.34357488 |
17 | rhodopsin mediated signaling pathway (GO:0016056) | 4.29427816 |
18 | positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) | 4.28267596 |
19 | adult heart development (GO:0007512) | 4.21200199 |
20 | negative regulation of potassium ion transmembrane transport (GO:1901380) | 4.12927516 |
21 | regulation of actin filament-based movement (GO:1903115) | 4.07831805 |
22 | ventricular cardiac muscle cell action potential (GO:0086005) | 4.05347672 |
23 | ketone body metabolic process (GO:1902224) | 4.05077005 |
24 | regulation of relaxation of muscle (GO:1901077) | 4.02987095 |
25 | DNA deamination (GO:0045006) | 3.96760502 |
26 | ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 3.92248886 |
27 | regulation of sarcomere organization (GO:0060297) | 3.90249964 |
28 | cytidine metabolic process (GO:0046087) | 3.89849426 |
29 | cytidine catabolic process (GO:0006216) | 3.89849426 |
30 | cytidine deamination (GO:0009972) | 3.89849426 |
31 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.88532422 |
32 | cardiac muscle contraction (GO:0060048) | 3.87884400 |
33 | behavioral response to nicotine (GO:0035095) | 3.87492041 |
34 | regulation of cell communication by electrical coupling (GO:0010649) | 3.82944808 |
35 | kynurenine metabolic process (GO:0070189) | 3.80057537 |
36 | cardiac muscle tissue morphogenesis (GO:0055008) | 3.77963994 |
37 | detection of calcium ion (GO:0005513) | 3.74014086 |
38 | regulation of membrane repolarization (GO:0060306) | 3.73193763 |
39 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.61269964 |
40 | regulation of cardioblast differentiation (GO:0051890) | 3.60844421 |
41 | regulation of striated muscle contraction (GO:0006942) | 3.57411398 |
42 | regulation of ATP catabolic process (GO:1903289) | 3.55262804 |
43 | regulation of ATPase activity (GO:0043462) | 3.55262804 |
44 | positive regulation of action potential (GO:0045760) | 3.53915396 |
45 | cardiac muscle cell development (GO:0055013) | 3.53462040 |
46 | muscle filament sliding (GO:0030049) | 3.52797588 |
47 | actin-myosin filament sliding (GO:0033275) | 3.52797588 |
48 | cardiac muscle tissue development (GO:0048738) | 3.51199530 |
49 | regulation of cardiac muscle contraction (GO:0055117) | 3.50584341 |
50 | regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) | 3.50396354 |
51 | indolalkylamine catabolic process (GO:0046218) | 3.44690589 |
52 | tryptophan catabolic process (GO:0006569) | 3.44690589 |
53 | indole-containing compound catabolic process (GO:0042436) | 3.44690589 |
54 | nephron tubule morphogenesis (GO:0072078) | 3.44370650 |
55 | nephron epithelium morphogenesis (GO:0072088) | 3.44370650 |
56 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.38468947 |
57 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.37694859 |
58 | response to epinephrine (GO:0071871) | 3.37232832 |
59 | muscle tissue morphogenesis (GO:0060415) | 3.35441036 |
60 | cardiac cell development (GO:0055006) | 3.31914150 |
61 | fatty acid transmembrane transport (GO:1902001) | 3.31850985 |
62 | cardiac right ventricle morphogenesis (GO:0003215) | 3.30699245 |
63 | endoderm formation (GO:0001706) | 3.30139843 |
64 | ATP biosynthetic process (GO:0006754) | 3.25821063 |
65 | photoreceptor cell maintenance (GO:0045494) | 3.24257852 |
66 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.24089110 |
67 | axon ensheathment in central nervous system (GO:0032291) | 3.22536598 |
68 | central nervous system myelination (GO:0022010) | 3.22536598 |
69 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.22349438 |
70 | cell communication involved in cardiac conduction (GO:0086065) | 3.21929028 |
71 | regulation of heart rate (GO:0002027) | 3.21807105 |
72 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.20917850 |
73 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.20078455 |
74 | neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976) | 3.19895759 |
75 | cellular response to epinephrine stimulus (GO:0071872) | 3.19414686 |
76 | regulation of the force of heart contraction (GO:0002026) | 3.18947114 |
77 | regulation of cardiac muscle cell contraction (GO:0086004) | 3.18599739 |
78 | neuron cell-cell adhesion (GO:0007158) | 3.16229610 |
79 | positive regulation of ATP catabolic process (GO:1903291) | 3.14899164 |
80 | positive regulation of ATPase activity (GO:0032781) | 3.14899164 |
81 | cardiac ventricle formation (GO:0003211) | 3.14464939 |
82 | regulation of skeletal muscle contraction (GO:0014819) | 3.09437853 |
83 | actin-mediated cell contraction (GO:0070252) | 3.08579166 |
84 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.08140645 |
85 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.08140645 |
86 | inner mitochondrial membrane organization (GO:0007007) | 3.07818171 |
87 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.07201564 |
88 | striated muscle contraction (GO:0006941) | 3.06827354 |
89 | cardiac muscle hypertrophy (GO:0003300) | 3.06404144 |
90 | heart process (GO:0003015) | 3.04971858 |
91 | heart contraction (GO:0060047) | 3.04971858 |
92 | cardiac muscle cell action potential (GO:0086001) | 3.03318276 |
93 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.03241951 |
94 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.02854867 |
95 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.02055127 |
96 | atrial septum morphogenesis (GO:0060413) | 3.00764311 |
97 | cardiac chamber formation (GO:0003207) | 3.00192973 |
98 | potassium ion export (GO:0071435) | 2.99266904 |
99 | hydrogen ion transmembrane transport (GO:1902600) | 2.98395838 |
100 | response to caffeine (GO:0031000) | 2.97947918 |
101 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 2.96856314 |
102 | heart trabecula formation (GO:0060347) | 2.95538124 |
103 | actomyosin structure organization (GO:0031032) | 2.95500609 |
104 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.95391185 |
105 | photoreceptor cell differentiation (GO:0046530) | 2.95261779 |
106 | eye photoreceptor cell differentiation (GO:0001754) | 2.95261779 |
107 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 2.94896432 |
108 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.94328529 |
109 | long-chain fatty acid biosynthetic process (GO:0042759) | 2.94001349 |
110 | auditory receptor cell stereocilium organization (GO:0060088) | 2.92956636 |
111 | relaxation of cardiac muscle (GO:0055119) | 2.91453978 |
112 | cardiac conduction (GO:0061337) | 2.90525310 |
113 | positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 2.89050445 |
114 | cardiac muscle cell action potential involved in contraction (GO:0086002) | 2.88572040 |
115 | striated muscle hypertrophy (GO:0014897) | 2.88137959 |
116 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.87504769 |
117 | fucose catabolic process (GO:0019317) | 2.87198899 |
118 | L-fucose metabolic process (GO:0042354) | 2.87198899 |
119 | L-fucose catabolic process (GO:0042355) | 2.87198899 |
120 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.85813184 |
121 | regulation of heart contraction (GO:0008016) | 2.82877064 |
122 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.82432480 |
123 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.82151067 |
124 | detection of light stimulus involved in visual perception (GO:0050908) | 2.82151067 |
125 | regulation of action potential (GO:0098900) | 2.81869125 |
126 | regulation of calcium ion transmembrane transport (GO:1903169) | 2.80441557 |
127 | regulation of calcium ion transmembrane transporter activity (GO:1901019) | 2.80441557 |
128 | sulfate transmembrane transport (GO:1902358) | 2.79279306 |
129 | regulation of catecholamine metabolic process (GO:0042069) | 2.79265078 |
130 | regulation of dopamine metabolic process (GO:0042053) | 2.79265078 |
131 | short-term memory (GO:0007614) | 2.78457717 |
132 | positive regulation of heart rate (GO:0010460) | 2.77579730 |
133 | muscle hypertrophy (GO:0014896) | 2.77554331 |
134 | indolalkylamine metabolic process (GO:0006586) | 2.73999262 |
135 | renal tubule morphogenesis (GO:0061333) | 2.72370242 |
136 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.70284724 |
137 | photoreceptor cell development (GO:0042461) | 2.69643430 |
138 | carnitine shuttle (GO:0006853) | 2.68569487 |
139 | positive regulation of fatty acid oxidation (GO:0046321) | 2.65799710 |
140 | cardiac septum development (GO:0003279) | 2.65094535 |
141 | positive regulation of sodium ion transport (GO:0010765) | 2.65080110 |
142 | membrane depolarization during action potential (GO:0086010) | 2.63662149 |
143 | adrenergic receptor signaling pathway (GO:0071875) | 2.61919363 |
144 | tryptophan metabolic process (GO:0006568) | 2.60779943 |
145 | cell communication by electrical coupling (GO:0010644) | 2.59384000 |
146 | regulation of memory T cell differentiation (GO:0043380) | 2.58272403 |
147 | negative regulation of heart rate (GO:0010459) | 2.57021407 |
148 | respiratory chain complex IV assembly (GO:0008535) | 2.56926420 |
149 | action potential (GO:0001508) | 2.55602778 |
150 | positive regulation of defense response to virus by host (GO:0002230) | 2.53124883 |
151 | response to pheromone (GO:0019236) | 2.52966962 |
152 | neuronal action potential (GO:0019228) | 2.52817682 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.77931048 |
2 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.25419947 |
3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.08875619 |
4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.84943534 |
5 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.64821881 |
6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.57548148 |
7 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.53707702 |
8 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.52074555 |
9 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.41304672 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.38880902 |
11 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.37604476 |
12 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.29731878 |
13 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.18963100 |
14 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.16601265 |
15 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.12643548 |
16 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.12165464 |
17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.11855543 |
18 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.10763000 |
19 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.10763000 |
20 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.10446868 |
21 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.08509990 |
22 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.07116829 |
23 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.00716986 |
24 | * EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.93151714 |
25 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.84660149 |
26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.82199384 |
27 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.82059253 |
28 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.82007497 |
29 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.78472830 |
30 | * SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.77400135 |
31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.73910412 |
32 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.65105241 |
33 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.65079594 |
34 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.63038780 |
35 | P300_19829295_ChIP-Seq_ESCs_Human | 1.61521877 |
36 | * RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.61287325 |
37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.56050981 |
38 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.54232978 |
39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.53822091 |
40 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.52749614 |
41 | ERA_21632823_ChIP-Seq_H3396_Human | 1.50408774 |
42 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.49360525 |
43 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.48755269 |
44 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.48715872 |
45 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.47614345 |
46 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.46546572 |
47 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.45848614 |
48 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.44923151 |
49 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.43918941 |
50 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.43763115 |
51 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.41919330 |
52 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.41131221 |
53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.40616171 |
54 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.40232114 |
55 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40148321 |
56 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.37484532 |
57 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.36623680 |
58 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.35360164 |
59 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.33080042 |
60 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.32675508 |
61 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.31353461 |
62 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.31238690 |
63 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.31140512 |
64 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.28295467 |
65 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.26283654 |
66 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.25025735 |
67 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.25003174 |
68 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.24560278 |
69 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24354506 |
70 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.24165804 |
71 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.24030412 |
72 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.21735260 |
73 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.21581476 |
74 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.21306157 |
75 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.21270266 |
76 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.19673640 |
77 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.18145520 |
78 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.17857607 |
79 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.16731731 |
80 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16507171 |
81 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.15779760 |
82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15502803 |
83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15502803 |
84 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15337887 |
85 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.15298357 |
86 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.14819541 |
87 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.14526211 |
88 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.14357104 |
89 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.14300971 |
90 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13903371 |
91 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.13430123 |
92 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.12708605 |
93 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.12198728 |
94 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.12070241 |
95 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11496247 |
96 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.11395465 |
97 | * CTCF_27219007_Chip-Seq_Bcells_Human | 1.10549000 |
98 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10377546 |
99 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.10127547 |
100 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.09874330 |
101 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.09748833 |
102 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.09588393 |
103 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09281089 |
104 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.09275397 |
105 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.08717959 |
106 | * PHF8_20622853_ChIP-Seq_HELA_Human | 1.08597539 |
107 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.08518167 |
108 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.08298385 |
109 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06979695 |
110 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.06786935 |
111 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.06095938 |
112 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.06045953 |
113 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.05964224 |
114 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.05905541 |
115 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.05425550 |
116 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.05319410 |
117 | EWS_26573619_Chip-Seq_HEK293_Human | 1.05296786 |
118 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.04351622 |
119 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.03753615 |
120 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.03649968 |
121 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.02977292 |
122 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.02953016 |
123 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.02723335 |
124 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02460130 |
125 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02460130 |
126 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.02445589 |
127 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.02372690 |
128 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01734640 |
129 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.01692992 |
130 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.00721111 |
131 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.00590997 |
132 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.99901123 |
133 | TCF4_23295773_ChIP-Seq_U87_Human | 0.98979998 |
134 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.98708040 |
135 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.98479996 |
136 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.98232332 |
137 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.97924490 |
138 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.97169209 |
139 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 0.97060916 |
140 | * PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.96847757 |
141 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.96587639 |
142 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96191397 |
143 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.96145059 |
144 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95147457 |
145 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.94448302 |
146 | KDM2B_26808549_Chip-Seq_REH_Human | 0.94265015 |
147 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.93684231 |
148 | * NFYB_21822215_ChIP-Seq_K562_Human | 0.92887311 |
149 | * TBL1_22424771_ChIP-Seq_293T_Human | 0.92872825 |
150 | STAT3_23295773_ChIP-Seq_U87_Human | 0.92741955 |
151 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.91996565 |
152 | AR_25329375_ChIP-Seq_VCAP_Human | 0.91972505 |
153 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.91675391 |
154 | GATA4_25053715_ChIP-Seq_YYC3_Human | 0.91673648 |
155 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91375255 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002837_dystrophic_cardiac_calcinosis | 5.06751706 |
2 | MP0004215_abnormal_myocardial_fiber | 3.75134015 |
3 | MP0000751_myopathy | 3.64541590 |
4 | MP0004084_abnormal_cardiac_muscle | 3.60829528 |
5 | MP0003880_abnormal_central_pattern | 3.18287762 |
6 | MP0003646_muscle_fatigue | 3.14693049 |
7 | MP0003950_abnormal_plasma_membrane | 2.88662568 |
8 | MP0004036_abnormal_muscle_relaxation | 2.88035512 |
9 | MP0005551_abnormal_eye_electrophysiolog | 2.82438643 |
10 | MP0003137_abnormal_impulse_conducting | 2.69200202 |
11 | MP0005330_cardiomyopathy | 2.57335913 |
12 | MP0006072_abnormal_retinal_apoptosis | 2.31829170 |
13 | MP0000749_muscle_degeneration | 2.31580223 |
14 | MP0002972_abnormal_cardiac_muscle | 2.20796388 |
15 | MP0004043_abnormal_pH_regulation | 2.09033971 |
16 | MP0004085_abnormal_heartbeat | 2.08916158 |
17 | MP0000013_abnormal_adipose_tissue | 2.07596132 |
18 | MP0006276_abnormal_autonomic_nervous | 2.01243175 |
19 | MP0005253_abnormal_eye_physiology | 2.00546329 |
20 | MP0001529_abnormal_vocalization | 1.98675637 |
21 | MP0003195_calcinosis | 1.98494049 |
22 | MP0003011_delayed_dark_adaptation | 1.97370318 |
23 | MP0004145_abnormal_muscle_electrophysio | 1.95332685 |
24 | MP0002876_abnormal_thyroid_physiology | 1.93891225 |
25 | MP0005409_darkened_coat_color | 1.90033295 |
26 | MP0005423_abnormal_somatic_nervous | 1.89889507 |
27 | MP0008775_abnormal_heart_ventricle | 1.88503505 |
28 | MP0005620_abnormal_muscle_contractility | 1.86284781 |
29 | MP0008875_abnormal_xenobiotic_pharmacok | 1.85964381 |
30 | MP0005670_abnormal_white_adipose | 1.78054361 |
31 | MP0001905_abnormal_dopamine_level | 1.77989402 |
32 | MP0009046_muscle_twitch | 1.77487315 |
33 | MP0004484_altered_response_of | 1.75856371 |
34 | MP0003136_yellow_coat_color | 1.69103812 |
35 | MP0002272_abnormal_nervous_system | 1.68283990 |
36 | MP0002822_catalepsy | 1.66339280 |
37 | MP0009745_abnormal_behavioral_response | 1.63300088 |
38 | MP0001661_extended_life_span | 1.61741214 |
39 | MP0002138_abnormal_hepatobiliary_system | 1.57847600 |
40 | MP0001486_abnormal_startle_reflex | 1.57010857 |
41 | MP0005085_abnormal_gallbladder_physiolo | 1.53682982 |
42 | MP0003252_abnormal_bile_duct | 1.52728918 |
43 | MP0001544_abnormal_cardiovascular_syste | 1.52706594 |
44 | MP0005385_cardiovascular_system_phenoty | 1.52706594 |
45 | MP0002106_abnormal_muscle_physiology | 1.52283419 |
46 | MP0002234_abnormal_pharynx_morphology | 1.52187438 |
47 | MP0000750_abnormal_muscle_regeneration | 1.49747659 |
48 | MP0002064_seizures | 1.48802503 |
49 | MP0002127_abnormal_cardiovascular_syste | 1.48186241 |
50 | MP0006138_congestive_heart_failure | 1.45361031 |
51 | MP0003635_abnormal_synaptic_transmissio | 1.45249383 |
52 | MP0001188_hyperpigmentation | 1.43153946 |
53 | MP0004087_abnormal_muscle_fiber | 1.41605198 |
54 | MP0002638_abnormal_pupillary_reflex | 1.40634889 |
55 | MP0002572_abnormal_emotion/affect_behav | 1.37068384 |
56 | MP0004142_abnormal_muscle_tone | 1.36210059 |
57 | MP0008872_abnormal_physiological_respon | 1.36105376 |
58 | MP0002735_abnormal_chemical_nociception | 1.34806326 |
59 | MP0003828_pulmonary_edema | 1.33167262 |
60 | MP0003567_abnormal_fetal_cardiomyocyte | 1.32591657 |
61 | MP0004147_increased_porphyrin_level | 1.29872386 |
62 | MP0005171_absent_coat_pigmentation | 1.28439636 |
63 | MP0001968_abnormal_touch/_nociception | 1.27939801 |
64 | MP0000427_abnormal_hair_cycle | 1.26078795 |
65 | MP0005332_abnormal_amino_acid | 1.25667845 |
66 | MP0004270_analgesia | 1.25501454 |
67 | MP0005369_muscle_phenotype | 1.24843008 |
68 | MP0001986_abnormal_taste_sensitivity | 1.24225572 |
69 | MP0002102_abnormal_ear_morphology | 1.23004314 |
70 | MP0004130_abnormal_muscle_cell | 1.21733168 |
71 | MP0005360_urolithiasis | 1.21290326 |
72 | MP0005083_abnormal_biliary_tract | 1.20173750 |
73 | MP0004859_abnormal_synaptic_plasticity | 1.17987986 |
74 | MP0002332_abnormal_exercise_endurance | 1.17941666 |
75 | MP0001440_abnormal_grooming_behavior | 1.17757370 |
76 | MP0004924_abnormal_behavior | 1.17445400 |
77 | MP0005386_behavior/neurological_phenoty | 1.17445400 |
78 | MP0002734_abnormal_mechanical_nocicepti | 1.14629974 |
79 | MP0002067_abnormal_sensory_capabilities | 1.14510988 |
80 | MP0006292_abnormal_olfactory_placode | 1.14507598 |
81 | MP0002063_abnormal_learning/memory/cond | 1.14486483 |
82 | MP0010630_abnormal_cardiac_muscle | 1.14434556 |
83 | MP0004381_abnormal_hair_follicle | 1.13487946 |
84 | MP0000566_synostosis | 1.13391715 |
85 | MP0002229_neurodegeneration | 1.13220598 |
86 | MP0005645_abnormal_hypothalamus_physiol | 1.12800177 |
87 | MP0001984_abnormal_olfaction | 1.11611089 |
88 | MP0004510_myositis | 1.11427052 |
89 | MP0009384_cardiac_valve_regurgitation | 1.10725773 |
90 | MP0005365_abnormal_bile_salt | 1.08877582 |
91 | MP0005195_abnormal_posterior_eye | 1.08112145 |
92 | MP0004742_abnormal_vestibular_system | 1.07286356 |
93 | MP0002752_abnormal_somatic_nervous | 1.07119746 |
94 | MP0001970_abnormal_pain_threshold | 1.07076664 |
95 | MP0010386_abnormal_urinary_bladder | 1.03316301 |
96 | MP0002736_abnormal_nociception_after | 1.02496338 |
97 | MP0000747_muscle_weakness | 1.01341340 |
98 | MP0000759_abnormal_skeletal_muscle | 0.98006253 |
99 | MP0001485_abnormal_pinna_reflex | 0.97320552 |
100 | MP0005623_abnormal_meninges_morphology | 0.96025420 |
101 | MP0001873_stomach_inflammation | 0.95833657 |
102 | MP0000920_abnormal_myelination | 0.94896315 |
103 | MP0001501_abnormal_sleep_pattern | 0.94692957 |
104 | MP0001502_abnormal_circadian_rhythm | 0.94234619 |
105 | MP0002882_abnormal_neuron_morphology | 0.93013807 |
106 | MP0000003_abnormal_adipose_tissue | 0.91744012 |
107 | MP0001765_abnormal_ion_homeostasis | 0.91523622 |
108 | MP0002184_abnormal_innervation | 0.90266606 |
109 | MP0006036_abnormal_mitochondrial_physio | 0.88568950 |
110 | MP0005451_abnormal_body_composition | 0.88349294 |
111 | MP0000778_abnormal_nervous_system | 0.85604100 |
112 | MP0006035_abnormal_mitochondrial_morpho | 0.85235361 |
113 | MP0000538_abnormal_urinary_bladder | 0.84889572 |
114 | MP0000026_abnormal_inner_ear | 0.83693803 |
115 | MP0002090_abnormal_vision | 0.83296958 |
116 | MP0002269_muscular_atrophy | 0.79182109 |
117 | MP0000383_abnormal_hair_follicle | 0.78279949 |
118 | MP0009379_abnormal_foot_pigmentation | 0.78192279 |
119 | MP0002733_abnormal_thermal_nociception | 0.77978630 |
120 | MP0002557_abnormal_social/conspecific_i | 0.77167410 |
121 | MP0008961_abnormal_basal_metabolism | 0.77099474 |
122 | MP0008569_lethality_at_weaning | 0.76363071 |
123 | MP0001963_abnormal_hearing_physiology | 0.75648532 |
124 | MP0002909_abnormal_adrenal_gland | 0.74856336 |
125 | MP0005646_abnormal_pituitary_gland | 0.74779201 |
126 | MP0000230_abnormal_systemic_arterial | 0.74357576 |
127 | MP0005165_increased_susceptibility_to | 0.73846822 |
128 | MP0005379_endocrine/exocrine_gland_phen | 0.72866622 |
129 | MP0001348_abnormal_lacrimal_gland | 0.72276706 |
130 | MP0002693_abnormal_pancreas_physiology | 0.71695751 |
131 | MP0002066_abnormal_motor_capabilities/c | 0.70776470 |
132 | MP0002160_abnormal_reproductive_system | 0.68066224 |
133 | MP0005174_abnormal_tail_pigmentation | 0.67466426 |
134 | MP0009643_abnormal_urine_homeostasis | 0.65959649 |
135 | MP0002163_abnormal_gland_morphology | 0.65727482 |
136 | MP0001756_abnormal_urination | 0.64719895 |
137 | MP0003045_fibrosis | 0.64342210 |
138 | MP0010329_abnormal_lipoprotein_level | 0.61549409 |
139 | MP0005084_abnormal_gallbladder_morpholo | 0.60627472 |
140 | MP0005448_abnormal_energy_balance | 0.60140860 |
141 | MP0002933_joint_inflammation | 0.60035116 |
142 | MP0005410_abnormal_fertilization | 0.58675617 |
143 | MP0000266_abnormal_heart_morphology | 0.57490615 |
144 | MP0001944_abnormal_pancreas_morphology | 0.57169711 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Sudden death (HP:0001699) | 6.33590727 |
2 | Acute necrotizing encephalopathy (HP:0006965) | 4.86915507 |
3 | Atrial fibrillation (HP:0005110) | 4.79859785 |
4 | Ventricular tachycardia (HP:0004756) | 4.76439890 |
5 | Syncope (HP:0001279) | 4.75563535 |
6 | Congenital stationary night blindness (HP:0007642) | 4.66557077 |
7 | Primary atrial arrhythmia (HP:0001692) | 4.52416693 |
8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.42856839 |
9 | Supraventricular tachycardia (HP:0004755) | 4.39563174 |
10 | Calf muscle hypertrophy (HP:0008981) | 4.35669876 |
11 | Supraventricular arrhythmia (HP:0005115) | 4.26454120 |
12 | Mitochondrial inheritance (HP:0001427) | 4.23438760 |
13 | Muscle hypertrophy of the lower extremities (HP:0008968) | 4.16873589 |
14 | Prolonged QT interval (HP:0001657) | 4.09358012 |
15 | Progressive macrocephaly (HP:0004481) | 4.02188780 |
16 | Abnormality of the calf musculature (HP:0001430) | 3.87590877 |
17 | Optic disc pallor (HP:0000543) | 3.83864307 |
18 | Acute encephalopathy (HP:0006846) | 3.68070688 |
19 | Increased CSF lactate (HP:0002490) | 3.54270027 |
20 | Muscle fiber splitting (HP:0003555) | 3.52366948 |
21 | Central scotoma (HP:0000603) | 3.49674714 |
22 | Hepatocellular necrosis (HP:0001404) | 3.49588595 |
23 | Lipoatrophy (HP:0100578) | 3.48961971 |
24 | Bony spicule pigmentary retinopathy (HP:0007737) | 3.30234762 |
25 | Palpitations (HP:0001962) | 3.27744883 |
26 | Pancreatic cysts (HP:0001737) | 3.23889247 |
27 | Hepatic necrosis (HP:0002605) | 3.18555666 |
28 | Abnormality of the renal cortex (HP:0011035) | 3.18088411 |
29 | Attenuation of retinal blood vessels (HP:0007843) | 3.17657939 |
30 | Right ventricular cardiomyopathy (HP:0011663) | 3.11015104 |
31 | Type II lissencephaly (HP:0007260) | 3.08427172 |
32 | Exercise-induced myalgia (HP:0003738) | 3.07927618 |
33 | Increased hepatocellular lipid droplets (HP:0006565) | 3.06059610 |
34 | Dilated cardiomyopathy (HP:0001644) | 3.05886306 |
35 | Ventricular fibrillation (HP:0001663) | 3.03213253 |
36 | Abnormal EKG (HP:0003115) | 3.01546235 |
37 | Subaortic stenosis (HP:0001682) | 3.00366011 |
38 | Abnormality of the left ventricular outflow tract (HP:0011103) | 3.00366011 |
39 | Ventricular arrhythmia (HP:0004308) | 2.95136385 |
40 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.93234807 |
41 | Left ventricular hypertrophy (HP:0001712) | 2.92691813 |
42 | Abnormality of midbrain morphology (HP:0002418) | 2.91662191 |
43 | Molar tooth sign on MRI (HP:0002419) | 2.91662191 |
44 | Hyperventilation (HP:0002883) | 2.81024096 |
45 | Polydipsia (HP:0001959) | 2.77034440 |
46 | Abnormal drinking behavior (HP:0030082) | 2.77034440 |
47 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.76876618 |
48 | Exercise intolerance (HP:0003546) | 2.76212089 |
49 | Lipid accumulation in hepatocytes (HP:0006561) | 2.75952369 |
50 | Nephronophthisis (HP:0000090) | 2.74163194 |
51 | Pancreatic fibrosis (HP:0100732) | 2.71445272 |
52 | Focal motor seizures (HP:0011153) | 2.69326538 |
53 | Tubular atrophy (HP:0000092) | 2.66644877 |
54 | Respiratory failure (HP:0002878) | 2.64457304 |
55 | Renal Fanconi syndrome (HP:0001994) | 2.64249997 |
56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.63322502 |
57 | Increased intramyocellular lipid droplets (HP:0012240) | 2.61993014 |
58 | True hermaphroditism (HP:0010459) | 2.61245747 |
59 | Scotoma (HP:0000575) | 2.60236228 |
60 | Severe muscular hypotonia (HP:0006829) | 2.59115862 |
61 | Cerebral edema (HP:0002181) | 2.54489631 |
62 | Hyporeflexia of lower limbs (HP:0002600) | 2.54460329 |
63 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.54144501 |
64 | Pheochromocytoma (HP:0002666) | 2.53110745 |
65 | Abnormality of the renal medulla (HP:0100957) | 2.52846076 |
66 | Renal cortical cysts (HP:0000803) | 2.51072262 |
67 | Congenital, generalized hypertrichosis (HP:0004540) | 2.49186658 |
68 | Abnormality of macular pigmentation (HP:0008002) | 2.44064084 |
69 | Bundle branch block (HP:0011710) | 2.42010802 |
70 | Limb dystonia (HP:0002451) | 2.41115096 |
71 | Chorioretinal atrophy (HP:0000533) | 2.39666738 |
72 | Gaze-evoked nystagmus (HP:0000640) | 2.39539140 |
73 | Lactic acidosis (HP:0003128) | 2.38575291 |
74 | Neuroendocrine neoplasm (HP:0100634) | 2.34442435 |
75 | Heart block (HP:0012722) | 2.34009626 |
76 | Decreased central vision (HP:0007663) | 2.33582872 |
77 | Testicular atrophy (HP:0000029) | 2.30503791 |
78 | Exercise-induced muscle cramps (HP:0003710) | 2.28662994 |
79 | Hypoplastic left heart (HP:0004383) | 2.25790959 |
80 | EMG: myopathic abnormalities (HP:0003458) | 2.25513258 |
81 | Genetic anticipation (HP:0003743) | 2.25502062 |
82 | Large for gestational age (HP:0001520) | 2.25325417 |
83 | Cystic liver disease (HP:0006706) | 2.23947210 |
84 | Increased muscle lipid content (HP:0009058) | 2.23797161 |
85 | Leukodystrophy (HP:0002415) | 2.23585059 |
86 | Congenital sensorineural hearing impairment (HP:0008527) | 2.23571617 |
87 | Congenital malformation of the right heart (HP:0011723) | 2.23481276 |
88 | Double outlet right ventricle (HP:0001719) | 2.23481276 |
89 | Pulmonary artery stenosis (HP:0004415) | 2.23234663 |
90 | Ketoacidosis (HP:0001993) | 2.22988603 |
91 | Myotonia (HP:0002486) | 2.20182321 |
92 | Cerebellar dysplasia (HP:0007033) | 2.18914591 |
93 | Progressive external ophthalmoplegia (HP:0000590) | 2.18647373 |
94 | Parakeratosis (HP:0001036) | 2.15806696 |
95 | Atrioventricular block (HP:0001678) | 2.14616547 |
96 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.13942046 |
97 | Polyuria (HP:0000103) | 2.13635288 |
98 | Patent foramen ovale (HP:0001655) | 2.13458574 |
99 | Abnormal atrioventricular conduction (HP:0005150) | 2.12617404 |
100 | Dyschromatopsia (HP:0007641) | 2.12122687 |
101 | Ketosis (HP:0001946) | 2.09816439 |
102 | Increased corneal curvature (HP:0100692) | 2.09688797 |
103 | Keratoconus (HP:0000563) | 2.09688797 |
104 | Pigmentary retinal degeneration (HP:0001146) | 2.04506554 |
105 | Tachypnea (HP:0002789) | 2.03236662 |
106 | 3-Methylglutaconic aciduria (HP:0003535) | 2.01917903 |
107 | Pendular nystagmus (HP:0012043) | 2.00676353 |
108 | Medial flaring of the eyebrow (HP:0010747) | 1.98803465 |
109 | Palmoplantar keratoderma (HP:0000982) | 1.98797172 |
110 | Rib fusion (HP:0000902) | 1.98719858 |
111 | Hyperglycinuria (HP:0003108) | 1.98390787 |
112 | Gait imbalance (HP:0002141) | 1.97865195 |
113 | Hypoplastic heart (HP:0001961) | 1.94314153 |
114 | Increased serum lactate (HP:0002151) | 1.93651646 |
115 | Hypoalbuminemia (HP:0003073) | 1.92856744 |
116 | Abnormal albumin level (HP:0012116) | 1.92856744 |
117 | Abnormality of alanine metabolism (HP:0010916) | 1.91690489 |
118 | Hyperalaninemia (HP:0003348) | 1.91690489 |
119 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.91690489 |
120 | Entropion (HP:0000621) | 1.90570517 |
121 | Bradycardia (HP:0001662) | 1.88341656 |
122 | X-linked dominant inheritance (HP:0001423) | 1.88298520 |
123 | Asymmetric septal hypertrophy (HP:0001670) | 1.87551558 |
124 | Vaginal atresia (HP:0000148) | 1.87526006 |
125 | Congenital primary aphakia (HP:0007707) | 1.87409420 |
126 | Decreased circulating renin level (HP:0003351) | 1.85032529 |
127 | Abnormal ciliary motility (HP:0012262) | 1.84785555 |
128 | Broad-based gait (HP:0002136) | 1.84607810 |
129 | Progressive microcephaly (HP:0000253) | 1.84565602 |
130 | Late onset (HP:0003584) | 1.84536915 |
131 | Genital tract atresia (HP:0001827) | 1.83521523 |
132 | Respiratory difficulties (HP:0002880) | 1.83498128 |
133 | Submucous cleft hard palate (HP:0000176) | 1.83362394 |
134 | Hypothermia (HP:0002045) | 1.83320116 |
135 | Dysmetric saccades (HP:0000641) | 1.82663728 |
136 | Retinitis pigmentosa (HP:0000510) | 1.80503794 |
137 | Chronic hepatic failure (HP:0100626) | 1.79179615 |
138 | Increased serum pyruvate (HP:0003542) | 1.78722403 |
139 | Abnormality of glycolysis (HP:0004366) | 1.78722403 |
140 | Abnormality of urine glucose concentration (HP:0011016) | 1.78526321 |
141 | Glycosuria (HP:0003076) | 1.78526321 |
142 | Myokymia (HP:0002411) | 1.78255031 |
143 | Abnormality of the foot musculature (HP:0001436) | 1.77899324 |
144 | Progressive cerebellar ataxia (HP:0002073) | 1.77899205 |
145 | Fair hair (HP:0002286) | 1.77844952 |
146 | Abnormal urine output (HP:0012590) | 1.77491440 |
147 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.76602531 |
148 | Hypoplasia of the fovea (HP:0007750) | 1.76602531 |
149 | Absent thumb (HP:0009777) | 1.75774088 |
150 | Limb hypertonia (HP:0002509) | 1.74933751 |
151 | Abolished electroretinogram (ERG) (HP:0000550) | 1.72217554 |
152 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.71636791 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FRK | 4.97131436 |
2 | CASK | 3.47875460 |
3 | MYLK | 3.13888066 |
4 | MUSK | 2.87060008 |
5 | MAPKAPK3 | 2.64193937 |
6 | TNIK | 2.63856630 |
7 | GRK7 | 2.54139850 |
8 | PHKG2 | 2.48590012 |
9 | PHKG1 | 2.48590012 |
10 | STK39 | 2.44888689 |
11 | OBSCN | 2.38561427 |
12 | TXK | 2.13106921 |
13 | CAMK2D | 1.90383331 |
14 | MST1R | 1.89233230 |
15 | PINK1 | 1.88498763 |
16 | LMTK2 | 1.85310784 |
17 | PBK | 1.83416644 |
18 | STK16 | 1.80135798 |
19 | INSRR | 1.74434109 |
20 | PNCK | 1.74083299 |
21 | WNK4 | 1.72764898 |
22 | STK24 | 1.70680388 |
23 | GRK1 | 1.69732697 |
24 | PKN1 | 1.68901307 |
25 | EPHA4 | 1.68185157 |
26 | PIK3CA | 1.63751715 |
27 | MARK1 | 1.53094439 |
28 | MAP4K2 | 1.50223290 |
29 | IRAK2 | 1.47665275 |
30 | ZAK | 1.47159308 |
31 | TTN | 1.47024919 |
32 | CAMK2A | 1.45617546 |
33 | MAP3K12 | 1.44396928 |
34 | MAP2K6 | 1.44263354 |
35 | NTRK3 | 1.43306367 |
36 | DMPK | 1.43236840 |
37 | MAP2K7 | 1.40976753 |
38 | NME1 | 1.40716875 |
39 | EPHA2 | 1.38417418 |
40 | MAPKAPK5 | 1.36046179 |
41 | TIE1 | 1.35057073 |
42 | BMPR1B | 1.34682844 |
43 | MAP3K7 | 1.34222621 |
44 | ADRBK2 | 1.30973497 |
45 | GRK5 | 1.30524438 |
46 | MET | 1.26620124 |
47 | FLT3 | 1.26006166 |
48 | PRKCE | 1.23630143 |
49 | CAMK2B | 1.18671660 |
50 | CDC42BPA | 1.18474990 |
51 | PKN2 | 1.18034567 |
52 | BMPR2 | 1.16783157 |
53 | MAPK13 | 1.14821081 |
54 | DAPK2 | 1.14536540 |
55 | NUAK1 | 1.12388257 |
56 | BCR | 1.11823004 |
57 | STK38L | 1.09937717 |
58 | WNK3 | 1.07105794 |
59 | PDK3 | 1.05911590 |
60 | PDK4 | 1.05911590 |
61 | ROCK2 | 1.02245744 |
62 | PLK2 | 1.01358314 |
63 | OXSR1 | 0.99783197 |
64 | PRPF4B | 0.99272066 |
65 | WNK1 | 0.98936118 |
66 | PDK2 | 0.98747643 |
67 | BCKDK | 0.97827837 |
68 | ADRBK1 | 0.97652081 |
69 | IRAK3 | 0.97385799 |
70 | ACVR1B | 0.96193537 |
71 | NTRK2 | 0.96111741 |
72 | UHMK1 | 0.94753964 |
73 | PRKAA1 | 0.94161836 |
74 | FGFR2 | 0.93943117 |
75 | NEK6 | 0.92846248 |
76 | LIMK1 | 0.91914935 |
77 | MAP3K4 | 0.91776383 |
78 | PAK3 | 0.90426852 |
79 | MST4 | 0.85193091 |
80 | IRAK1 | 0.85148900 |
81 | PRKD1 | 0.82517043 |
82 | MAPK12 | 0.80063777 |
83 | TAOK3 | 0.79655505 |
84 | CAMK2G | 0.79523098 |
85 | ROCK1 | 0.75913665 |
86 | PRKCI | 0.75274278 |
87 | PRKACA | 0.73891820 |
88 | FGR | 0.70076277 |
89 | CAMK1 | 0.69522904 |
90 | MKNK2 | 0.69519298 |
91 | TRPM7 | 0.68192834 |
92 | NME2 | 0.67634872 |
93 | IKBKB | 0.66758645 |
94 | CDK3 | 0.65147540 |
95 | FES | 0.64305506 |
96 | ITK | 0.62102534 |
97 | CSNK1G3 | 0.60076136 |
98 | CHUK | 0.59159192 |
99 | PRKD2 | 0.56713976 |
100 | PTK2B | 0.55963732 |
101 | NEK2 | 0.53767592 |
102 | DAPK3 | 0.52389933 |
103 | AKT3 | 0.52047774 |
104 | CDK5 | 0.50954225 |
105 | RPS6KA5 | 0.47061735 |
106 | PRKACB | 0.46488647 |
107 | CSNK1G2 | 0.46432224 |
108 | CAMKK2 | 0.46420656 |
109 | TLK1 | 0.45179926 |
110 | PRKG1 | 0.44781493 |
111 | FER | 0.42758984 |
112 | NTRK1 | 0.42488602 |
113 | MAP2K4 | 0.42219560 |
114 | IRAK4 | 0.42054283 |
115 | RIPK4 | 0.41838028 |
116 | ILK | 0.41492972 |
117 | EPHA3 | 0.41007181 |
118 | CSNK1A1L | 0.40903159 |
119 | CSNK1G1 | 0.40773287 |
120 | PRKCQ | 0.40246268 |
121 | CAMK4 | 0.38822744 |
122 | PRKCA | 0.37228240 |
123 | YES1 | 0.36571284 |
124 | PRKAA2 | 0.36389630 |
125 | PRKCG | 0.35508895 |
126 | SGK223 | 0.35402640 |
127 | SGK494 | 0.35402640 |
128 | DYRK1A | 0.35261680 |
129 | RPS6KA6 | 0.34790498 |
130 | KDR | 0.34772739 |
131 | PRKCH | 0.34321802 |
132 | DYRK2 | 0.33742328 |
133 | VRK1 | 0.32513679 |
134 | PRKACG | 0.32375590 |
135 | MAPK15 | 0.32273578 |
136 | NEK1 | 0.31733325 |
137 | MAPK11 | 0.30414963 |
138 | MAP2K1 | 0.29370393 |
139 | RPS6KB2 | 0.27420291 |
140 | CSNK1A1 | 0.26817522 |
141 | STK3 | 0.26747622 |
142 | STK11 | 0.25872499 |
143 | FGFR1 | 0.25481279 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.22942759 |
2 | Phototransduction_Homo sapiens_hsa04744 | 5.13447960 |
3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.58223887 |
4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 4.06522823 |
5 | Alzheimers disease_Homo sapiens_hsa05010 | 3.60745155 |
6 | Huntingtons disease_Homo sapiens_hsa05016 | 3.11711747 |
7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.70498682 |
8 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.46436448 |
9 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.35552548 |
10 | Fatty acid elongation_Homo sapiens_hsa00062 | 2.08837924 |
11 | Nicotine addiction_Homo sapiens_hsa05033 | 2.04209879 |
12 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.93795089 |
13 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.82291811 |
14 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.71947039 |
15 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.71335588 |
16 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.67141048 |
17 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.66920593 |
18 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.64501563 |
19 | Sulfur relay system_Homo sapiens_hsa04122 | 1.59408957 |
20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.54261180 |
21 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.51338987 |
22 | Taste transduction_Homo sapiens_hsa04742 | 1.47957330 |
23 | Morphine addiction_Homo sapiens_hsa05032 | 1.47894123 |
24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.47789985 |
25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.47403445 |
26 | GABAergic synapse_Homo sapiens_hsa04727 | 1.45483450 |
27 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.43373559 |
28 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.41707325 |
29 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.41235773 |
30 | Circadian entrainment_Homo sapiens_hsa04713 | 1.40944549 |
31 | ABC transporters_Homo sapiens_hsa02010 | 1.38502332 |
32 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.37116733 |
33 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.36675812 |
34 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.33477205 |
35 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.33456032 |
36 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.33203450 |
37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.28267115 |
38 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.25594227 |
39 | Olfactory transduction_Homo sapiens_hsa04740 | 1.25530995 |
40 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.21358863 |
41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.15474157 |
42 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.15044762 |
43 | Retinol metabolism_Homo sapiens_hsa00830 | 1.09221512 |
44 | Peroxisome_Homo sapiens_hsa04146 | 1.08141304 |
45 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.07895105 |
46 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.06382630 |
47 | Renin secretion_Homo sapiens_hsa04924 | 1.04794379 |
48 | Cocaine addiction_Homo sapiens_hsa05030 | 1.03296153 |
49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.01047855 |
50 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.00719136 |
51 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.00465568 |
52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.99896577 |
53 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.98022838 |
54 | Bile secretion_Homo sapiens_hsa04976 | 0.97906408 |
55 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.97568676 |
56 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.96864850 |
57 | Ribosome_Homo sapiens_hsa03010 | 0.95148865 |
58 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.95116663 |
59 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92787634 |
60 | Insulin secretion_Homo sapiens_hsa04911 | 0.92399668 |
61 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.91978362 |
62 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.90817572 |
63 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.90358709 |
64 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.89409817 |
65 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.82392066 |
66 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.82242180 |
67 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.81934377 |
68 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.81924340 |
69 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.81416709 |
70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.81237568 |
71 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.81192865 |
72 | Mineral absorption_Homo sapiens_hsa04978 | 0.80122176 |
73 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.79286562 |
74 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.78485536 |
75 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.77628709 |
76 | Salivary secretion_Homo sapiens_hsa04970 | 0.75446625 |
77 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.74716950 |
78 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.73670723 |
79 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71016720 |
80 | Axon guidance_Homo sapiens_hsa04360 | 0.70436931 |
81 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.70197052 |
82 | Homologous recombination_Homo sapiens_hsa03440 | 0.69586352 |
83 | RNA polymerase_Homo sapiens_hsa03020 | 0.69057475 |
84 | Long-term depression_Homo sapiens_hsa04730 | 0.66163087 |
85 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.65768409 |
86 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.65255412 |
87 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.64039122 |
88 | Protein export_Homo sapiens_hsa03060 | 0.63770837 |
89 | Long-term potentiation_Homo sapiens_hsa04720 | 0.62593975 |
90 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.61976976 |
91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61539792 |
92 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.60817285 |
93 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.60614217 |
94 | Circadian rhythm_Homo sapiens_hsa04710 | 0.58894842 |
95 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.58690329 |
96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.58462423 |
97 | RNA degradation_Homo sapiens_hsa03018 | 0.57793659 |
98 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.57269591 |
99 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.57055033 |
100 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.55914736 |
101 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.54214285 |
102 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.52105993 |
103 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.50872765 |
104 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.50673632 |
105 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.49655930 |
106 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.48541755 |
107 | Lysine degradation_Homo sapiens_hsa00310 | 0.47833369 |
108 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.47670531 |
109 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46172214 |
110 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.45946147 |
111 | Proteasome_Homo sapiens_hsa03050 | 0.45758143 |
112 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.45171670 |
113 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.44411030 |
114 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.44344060 |
115 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.44024508 |
116 | Viral myocarditis_Homo sapiens_hsa05416 | 0.43208342 |
117 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.42546882 |
118 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.40328582 |
119 | Purine metabolism_Homo sapiens_hsa00230 | 0.39709715 |
120 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.39564007 |
121 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.38987509 |
122 | Gap junction_Homo sapiens_hsa04540 | 0.38180884 |
123 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.35342380 |
124 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.32559378 |
125 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.32246313 |
126 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.29684438 |
127 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.29627741 |
128 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.28468746 |
129 | Melanogenesis_Homo sapiens_hsa04916 | 0.28326611 |
130 | Basal transcription factors_Homo sapiens_hsa03022 | 0.27096754 |
131 | Tight junction_Homo sapiens_hsa04530 | 0.27076247 |
132 | Carbon metabolism_Homo sapiens_hsa01200 | 0.22511770 |
133 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.18469251 |
134 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.18004655 |
135 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.16722803 |
136 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.15660871 |
137 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.15267954 |
138 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.15236769 |
139 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.15205732 |
140 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.14835467 |
141 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.11285886 |
142 | Histidine metabolism_Homo sapiens_hsa00340 | 0.10952394 |