Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 6.00215618 |
2 | synaptic vesicle maturation (GO:0016188) | 5.86612837 |
3 | synaptic vesicle exocytosis (GO:0016079) | 5.45771065 |
4 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 5.42876536 |
5 | vocalization behavior (GO:0071625) | 5.38601266 |
6 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 5.37660192 |
7 | locomotory exploration behavior (GO:0035641) | 5.34200017 |
8 | regulation of synaptic vesicle exocytosis (GO:2000300) | 5.25181999 |
9 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 5.15283780 |
10 | glutamate secretion (GO:0014047) | 5.13603182 |
11 | neuronal action potential propagation (GO:0019227) | 5.05545030 |
12 | protein localization to synapse (GO:0035418) | 4.74115523 |
13 | regulation of glutamate receptor signaling pathway (GO:1900449) | 4.70407183 |
14 | neuron cell-cell adhesion (GO:0007158) | 4.63694361 |
15 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 4.61520456 |
16 | regulation of synaptic vesicle transport (GO:1902803) | 4.60467618 |
17 | neurotransmitter secretion (GO:0007269) | 4.54968839 |
18 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 4.42973006 |
19 | regulation of neuronal synaptic plasticity (GO:0048168) | 4.38124329 |
20 | exploration behavior (GO:0035640) | 4.32305252 |
21 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 4.27768091 |
22 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.26823414 |
23 | dendritic spine morphogenesis (GO:0060997) | 4.21595062 |
24 | axon ensheathment in central nervous system (GO:0032291) | 4.21340962 |
25 | central nervous system myelination (GO:0022010) | 4.21340962 |
26 | glutamate receptor signaling pathway (GO:0007215) | 4.13670158 |
27 | synaptic transmission, glutamatergic (GO:0035249) | 4.10266802 |
28 | gamma-aminobutyric acid transport (GO:0015812) | 4.10248989 |
29 | L-amino acid import (GO:0043092) | 4.03638402 |
30 | layer formation in cerebral cortex (GO:0021819) | 4.01982419 |
31 | neuron-neuron synaptic transmission (GO:0007270) | 3.92809616 |
32 | regulation of synapse structural plasticity (GO:0051823) | 3.92328486 |
33 | positive regulation of dendritic spine morphogenesis (GO:0061003) | 3.89996567 |
34 | regulation of synapse maturation (GO:0090128) | 3.87150465 |
35 | neuromuscular process controlling posture (GO:0050884) | 3.80887075 |
36 | neurotransmitter transport (GO:0006836) | 3.80599711 |
37 | potassium ion homeostasis (GO:0055075) | 3.78264477 |
38 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 3.75313416 |
39 | neuron recognition (GO:0008038) | 3.72796783 |
40 | positive regulation of membrane potential (GO:0045838) | 3.72215091 |
41 | regulation of excitatory postsynaptic membrane potential (GO:0060079) | 3.70979543 |
42 | long-term memory (GO:0007616) | 3.69153455 |
43 | transmission of nerve impulse (GO:0019226) | 3.64229303 |
44 | neurotransmitter-gated ion channel clustering (GO:0072578) | 3.63485600 |
45 | cellular potassium ion homeostasis (GO:0030007) | 3.61589611 |
46 | amino acid import (GO:0043090) | 3.61125376 |
47 | regulation of postsynaptic membrane potential (GO:0060078) | 3.55905572 |
48 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.52648218 |
49 | proline transport (GO:0015824) | 3.52182001 |
50 | regulation of neurotransmitter secretion (GO:0046928) | 3.48471645 |
51 | regulation of vesicle fusion (GO:0031338) | 3.48049788 |
52 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.47276341 |
53 | regulation of ARF protein signal transduction (GO:0032012) | 3.47224844 |
54 | synaptic vesicle endocytosis (GO:0048488) | 3.46595283 |
55 | cerebellar Purkinje cell differentiation (GO:0021702) | 3.45700146 |
56 | regulation of neurotransmitter levels (GO:0001505) | 3.45447457 |
57 | neuromuscular process controlling balance (GO:0050885) | 3.45404188 |
58 | regulation of synaptic plasticity (GO:0048167) | 3.44970194 |
59 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.44967165 |
60 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.40464016 |
61 | activation of protein kinase A activity (GO:0034199) | 3.39800744 |
62 | postsynaptic membrane organization (GO:0001941) | 3.37518239 |
63 | regulation of dendritic spine morphogenesis (GO:0061001) | 3.36352316 |
64 | potassium ion import (GO:0010107) | 3.33980633 |
65 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.33417269 |
66 | glycine transport (GO:0015816) | 3.32940106 |
67 | positive regulation of synapse maturation (GO:0090129) | 3.32589269 |
68 | sodium ion export (GO:0071436) | 3.31502552 |
69 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.30351244 |
70 | long-term synaptic potentiation (GO:0060291) | 3.28945915 |
71 | axonal fasciculation (GO:0007413) | 3.27611602 |
72 | cerebellar granule cell differentiation (GO:0021707) | 3.26326754 |
73 | regulation of neurotransmitter transport (GO:0051588) | 3.23467161 |
74 | auditory behavior (GO:0031223) | 3.22874509 |
75 | G-protein coupled acetylcholine receptor signaling pathway (GO:0007213) | 3.17620608 |
76 | positive regulation of dendrite development (GO:1900006) | 3.16853273 |
77 | cellular sodium ion homeostasis (GO:0006883) | 3.16753293 |
78 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.15416403 |
79 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.15312641 |
80 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 3.13489144 |
81 | adult walking behavior (GO:0007628) | 3.13197290 |
82 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.12995116 |
83 | membrane hyperpolarization (GO:0060081) | 3.12297691 |
84 | presynaptic membrane assembly (GO:0097105) | 3.11838432 |
85 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.11559224 |
86 | neuronal ion channel clustering (GO:0045161) | 3.11238149 |
87 | cerebellar Purkinje cell layer development (GO:0021680) | 3.11216881 |
88 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.09808049 |
89 | dendritic spine organization (GO:0097061) | 3.08554558 |
90 | cell migration in hindbrain (GO:0021535) | 3.08432606 |
91 | membrane depolarization (GO:0051899) | 3.07686294 |
92 | positive regulation of neurotransmitter transport (GO:0051590) | 3.06671224 |
93 | presynaptic membrane organization (GO:0097090) | 3.05977534 |
94 | dendrite morphogenesis (GO:0048813) | 3.05817222 |
95 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.05334438 |
96 | response to auditory stimulus (GO:0010996) | 3.04852498 |
97 | positive regulation of neurotransmitter secretion (GO:0001956) | 3.03132525 |
98 | positive regulation of dendritic spine development (GO:0060999) | 3.02393747 |
99 | dicarboxylic acid transport (GO:0006835) | 3.01814949 |
100 | vesicle docking involved in exocytosis (GO:0006904) | 3.01705428 |
101 | neuromuscular process (GO:0050905) | 3.00648471 |
102 | learning (GO:0007612) | 3.00453770 |
103 | regulation of synaptic transmission (GO:0050804) | 2.99594727 |
104 | behavioral fear response (GO:0001662) | 2.99558309 |
105 | behavioral defense response (GO:0002209) | 2.99558309 |
106 | prepulse inhibition (GO:0060134) | 2.99124989 |
107 | negative regulation of dendrite morphogenesis (GO:0050774) | 2.98724078 |
108 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 2.98463374 |
109 | synapse assembly (GO:0007416) | 2.98284270 |
110 | cell communication by electrical coupling (GO:0010644) | 2.93994980 |
111 | synaptic transmission (GO:0007268) | 2.93674852 |
112 | negative regulation of microtubule polymerization (GO:0031115) | 2.93663460 |
113 | cell differentiation in hindbrain (GO:0021533) | 2.93305460 |
114 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.92360037 |
115 | regulation of respiratory system process (GO:0044065) | 2.91716601 |
116 | establishment of synaptic vesicle localization (GO:0097480) | 2.91694305 |
117 | synaptic vesicle transport (GO:0048489) | 2.91694305 |
118 | neuromuscular synaptic transmission (GO:0007274) | 2.91460297 |
119 | membrane depolarization during action potential (GO:0086010) | 2.91301522 |
120 | regulation of dendritic spine development (GO:0060998) | 2.91196624 |
121 | positive regulation of synaptic transmission (GO:0050806) | 2.90719419 |
122 | regulation of glutamate secretion (GO:0014048) | 2.90263748 |
123 | intraspecies interaction between organisms (GO:0051703) | 2.88222917 |
124 | response to parathyroid hormone (GO:0071107) | 2.88161747 |
125 | regulation of exocytosis (GO:0017157) | 2.85548492 |
126 | acidic amino acid transport (GO:0015800) | 2.85412541 |
127 | adenosine receptor signaling pathway (GO:0001973) | 2.85104813 |
128 | chemosensory behavior (GO:0007635) | 2.82266177 |
129 | dopamine receptor signaling pathway (GO:0007212) | 2.79237140 |
130 | regulation of dendrite morphogenesis (GO:0048814) | 2.79222818 |
131 | establishment of mitochondrion localization (GO:0051654) | 2.76416528 |
132 | behavioral response to cocaine (GO:0048148) | 2.74951107 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.04021369 |
2 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 3.38506529 |
3 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 3.25829159 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 3.25707830 |
5 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.18616225 |
6 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.15559465 |
7 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.89837087 |
8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.89837087 |
9 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.87110412 |
10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.81175859 |
11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.77961268 |
12 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.72888667 |
13 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 2.71322821 |
14 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.68432831 |
15 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.65840076 |
16 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.64620827 |
17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.64376221 |
18 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.61893100 |
19 | * LXR_22292898_ChIP-Seq_THP-1_Human | 2.52458498 |
20 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.49731912 |
21 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.47945680 |
22 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 2.42317473 |
23 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.42261361 |
24 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.42019613 |
25 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.30518955 |
26 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.18592360 |
27 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.16668788 |
28 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.13895707 |
29 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.11151794 |
30 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.10004748 |
31 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.97686596 |
32 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.92569162 |
33 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.83426920 |
34 | P68_20966046_ChIP-Seq_HELA_Human | 1.83166167 |
35 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.80445471 |
36 | * ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.76723695 |
37 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.75013242 |
38 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.70220869 |
39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.68541436 |
40 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.61689388 |
41 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.60259475 |
42 | * SMC4_20622854_ChIP-Seq_HELA_Human | 1.59763209 |
43 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.57397858 |
44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.54407797 |
45 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.54339046 |
46 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.52963947 |
47 | * CREB1_26743006_Chip-Seq_LNCaP_Human | 1.45368435 |
48 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.45208278 |
49 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.44865172 |
50 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.44593789 |
51 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.43417533 |
52 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.43160490 |
53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.43153606 |
54 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.40691837 |
55 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.37641524 |
56 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.37511096 |
57 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.37058391 |
58 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.36314789 |
59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.30398741 |
60 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.30032607 |
61 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.29550387 |
62 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.29150408 |
63 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.29049549 |
64 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.28986144 |
65 | * CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.28719178 |
66 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.27875705 |
67 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.26854940 |
68 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.26788658 |
69 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.26658475 |
70 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.25265024 |
71 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.22455416 |
72 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 1.21445663 |
73 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.20806538 |
74 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.20174705 |
75 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.19910378 |
76 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.18433331 |
77 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.17504400 |
78 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.17117923 |
79 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.16749321 |
80 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.15780366 |
81 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.15533438 |
82 | KDM2B_26808549_Chip-Seq_K562_Human | 1.14245607 |
83 | * CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.14174040 |
84 | SETDB1_19884255_ChIP-Seq_MESCs_Mouse | 1.13933495 |
85 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.13463757 |
86 | P300_19829295_ChIP-Seq_ESCs_Human | 1.12564462 |
87 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.12520339 |
88 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.09967149 |
89 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.09571929 |
90 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.09505522 |
91 | AR_19668381_ChIP-Seq_PC3_Human | 1.08832550 |
92 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.08642984 |
93 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.07844765 |
94 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.06624151 |
95 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.06515079 |
96 | SA1_27219007_Chip-Seq_Bcells_Human | 1.05597730 |
97 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.04943684 |
98 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.04919985 |
99 | AR_25329375_ChIP-Seq_VCAP_Human | 1.04866937 |
100 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03390036 |
101 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 1.03205089 |
102 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.02544310 |
103 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02282084 |
104 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01798718 |
105 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01732975 |
106 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.00456897 |
107 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.00334975 |
108 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.99361095 |
109 | STAT3_23295773_ChIP-Seq_U87_Human | 0.99103285 |
110 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.98493856 |
111 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.97846293 |
112 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.97164750 |
113 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.96585770 |
114 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.96424590 |
115 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.96021073 |
116 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.94626966 |
117 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.94369883 |
118 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.94160910 |
119 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.93774344 |
120 | VDR_22108803_ChIP-Seq_LS180_Human | 0.93084665 |
121 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.92274006 |
122 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.92153828 |
123 | JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse | 0.90712094 |
124 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.90152632 |
125 | TFAP2A_17053090_ChIP-ChIP_MCF-7_Human | 0.90104593 |
126 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.89972011 |
127 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.88420140 |
128 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.88142183 |
129 | * RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.87811782 |
130 | TCF4_23295773_ChIP-Seq_U87_Human | 0.87756813 |
131 | DPY_21335234_ChIP-Seq_ESCs_Mouse | 0.87488147 |
132 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.86920465 |
133 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.86793104 |
134 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86777719 |
135 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.86776536 |
136 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.85924767 |
137 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.85850503 |
138 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.85741131 |
139 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.84795984 |
140 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.84212585 |
141 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.83693439 |
142 | * SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.83528545 |
143 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.82959423 |
144 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.81809645 |
145 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.81027298 |
146 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.80759926 |
147 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80063102 |
148 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 0.78741355 |
149 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.77495517 |
150 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.76597923 |
151 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.75904786 |
152 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.74117527 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 6.18660576 |
2 | MP0003880_abnormal_central_pattern | 5.04810689 |
3 | MP0003635_abnormal_synaptic_transmissio | 4.15109536 |
4 | MP0004270_analgesia | 3.57767222 |
5 | MP0009745_abnormal_behavioral_response | 3.41334654 |
6 | MP0002063_abnormal_learning/memory/cond | 3.30648903 |
7 | MP0002064_seizures | 3.25877820 |
8 | MP0009046_muscle_twitch | 3.21538066 |
9 | MP0005423_abnormal_somatic_nervous | 2.98858254 |
10 | MP0001968_abnormal_touch/_nociception | 2.96482486 |
11 | MP0002572_abnormal_emotion/affect_behav | 2.84198860 |
12 | MP0002272_abnormal_nervous_system | 2.74925010 |
13 | MP0001486_abnormal_startle_reflex | 2.64228671 |
14 | MP0002734_abnormal_mechanical_nocicepti | 2.55492909 |
15 | MP0002822_catalepsy | 2.52793523 |
16 | MP0003123_paternal_imprinting | 2.35018361 |
17 | MP0001440_abnormal_grooming_behavior | 2.31661480 |
18 | MP0001501_abnormal_sleep_pattern | 2.25643930 |
19 | MP0002736_abnormal_nociception_after | 2.22396288 |
20 | MP0002735_abnormal_chemical_nociception | 2.15975854 |
21 | MP0002733_abnormal_thermal_nociception | 2.14009938 |
22 | MP0001970_abnormal_pain_threshold | 2.05582090 |
23 | MP0003329_amyloid_beta_deposits | 2.02449567 |
24 | MP0002067_abnormal_sensory_capabilities | 2.01548730 |
25 | MP0008569_lethality_at_weaning | 1.96803419 |
26 | MP0000778_abnormal_nervous_system | 1.91994550 |
27 | MP0006276_abnormal_autonomic_nervous | 1.90429280 |
28 | MP0002184_abnormal_innervation | 1.89419934 |
29 | MP0004885_abnormal_endolymph | 1.87671244 |
30 | MP0002557_abnormal_social/conspecific_i | 1.84508927 |
31 | MP0004142_abnormal_muscle_tone | 1.82360484 |
32 | MP0004924_abnormal_behavior | 1.72071313 |
33 | MP0005386_behavior/neurological_phenoty | 1.72071313 |
34 | MP0004811_abnormal_neuron_physiology | 1.70666435 |
35 | MP0000955_abnormal_spinal_cord | 1.68213900 |
36 | MP0001529_abnormal_vocalization | 1.60327961 |
37 | MP0004858_abnormal_nervous_system | 1.60222206 |
38 | MP0002882_abnormal_neuron_morphology | 1.51267464 |
39 | MP0002909_abnormal_adrenal_gland | 1.50467278 |
40 | MP0002066_abnormal_motor_capabilities/c | 1.50421878 |
41 | MP0001905_abnormal_dopamine_level | 1.47799239 |
42 | MP0003122_maternal_imprinting | 1.47091777 |
43 | MP0009780_abnormal_chondrocyte_physiolo | 1.42859135 |
44 | MP0005645_abnormal_hypothalamus_physiol | 1.42186742 |
45 | MP0001984_abnormal_olfaction | 1.40702971 |
46 | MP0003879_abnormal_hair_cell | 1.39334386 |
47 | MP0005646_abnormal_pituitary_gland | 1.39323753 |
48 | MP0003633_abnormal_nervous_system | 1.28404076 |
49 | MP0001502_abnormal_circadian_rhythm | 1.27631379 |
50 | MP0003787_abnormal_imprinting | 1.22046975 |
51 | MP0004742_abnormal_vestibular_system | 1.21928788 |
52 | MP0000920_abnormal_myelination | 1.19965158 |
53 | MP0002152_abnormal_brain_morphology | 1.14415597 |
54 | MP0003631_nervous_system_phenotype | 1.12550589 |
55 | MP0002229_neurodegeneration | 1.11548909 |
56 | MP0004145_abnormal_muscle_electrophysio | 1.08510165 |
57 | MP0004510_myositis | 1.08282830 |
58 | MP0000751_myopathy | 1.07463565 |
59 | MP0001346_abnormal_lacrimal_gland | 1.04914062 |
60 | MP0003634_abnormal_glial_cell | 1.04730782 |
61 | MP0004130_abnormal_muscle_cell | 1.01648036 |
62 | MP0008872_abnormal_physiological_respon | 1.01434317 |
63 | MP0002249_abnormal_larynx_morphology | 1.01321825 |
64 | MP0005551_abnormal_eye_electrophysiolog | 0.96930905 |
65 | MP0001188_hyperpigmentation | 0.95303087 |
66 | MP0000013_abnormal_adipose_tissue | 0.92331961 |
67 | MP0002069_abnormal_eating/drinking_beha | 0.91529476 |
68 | MP0005167_abnormal_blood-brain_barrier | 0.90641444 |
69 | MP0002752_abnormal_somatic_nervous | 0.89734339 |
70 | MP0001963_abnormal_hearing_physiology | 0.88812686 |
71 | MP0001348_abnormal_lacrimal_gland | 0.88090261 |
72 | MP0003690_abnormal_glial_cell | 0.87957249 |
73 | MP0003632_abnormal_nervous_system | 0.87335836 |
74 | MP0002089_abnormal_postnatal_growth/wei | 0.85741127 |
75 | MP0010386_abnormal_urinary_bladder | 0.84578115 |
76 | MP0001485_abnormal_pinna_reflex | 0.82733371 |
77 | MP0000566_synostosis | 0.82457604 |
78 | MP0008874_decreased_physiological_sensi | 0.81153668 |
79 | MP0005409_darkened_coat_color | 0.80903496 |
80 | MP0003137_abnormal_impulse_conducting | 0.80609470 |
81 | MP0005394_taste/olfaction_phenotype | 0.80381463 |
82 | MP0005499_abnormal_olfactory_system | 0.80381463 |
83 | MP0000604_amyloidosis | 0.79746981 |
84 | MP0004085_abnormal_heartbeat | 0.78756950 |
85 | MP0002638_abnormal_pupillary_reflex | 0.77857080 |
86 | MP0003172_abnormal_lysosome_physiology | 0.76980853 |
87 | MP0000631_abnormal_neuroendocrine_gland | 0.76030229 |
88 | MP0003283_abnormal_digestive_organ | 0.75938923 |
89 | MP0001177_atelectasis | 0.74327290 |
90 | MP0002653_abnormal_ependyma_morphology | 0.74163177 |
91 | MP0006072_abnormal_retinal_apoptosis | 0.72598975 |
92 | MP0005535_abnormal_body_temperature | 0.68582100 |
93 | MP0005464_abnormal_platelet_physiology | 0.65558704 |
94 | MP0000579_abnormal_nail_morphology | 0.64673603 |
95 | MP0003075_altered_response_to | 0.62380449 |
96 | MP0003861_abnormal_nervous_system | 0.61869055 |
97 | MP0005623_abnormal_meninges_morphology | 0.61827115 |
98 | MP0002837_dystrophic_cardiac_calcinosis | 0.61569790 |
99 | MP0004043_abnormal_pH_regulation | 0.60441805 |
100 | MP0003705_abnormal_hypodermis_morpholog | 0.59496632 |
101 | MP0001664_abnormal_digestion | 0.58350939 |
102 | MP0003121_genomic_imprinting | 0.58176393 |
103 | MP0008961_abnormal_basal_metabolism | 0.57546414 |
104 | MP0010769_abnormal_survival | 0.57378205 |
105 | MP0001943_abnormal_respiration | 0.56510366 |
106 | MP0000026_abnormal_inner_ear | 0.55900103 |
107 | MP0000747_muscle_weakness | 0.55709130 |
108 | MP0002082_postnatal_lethality | 0.55583710 |
109 | MP0010770_preweaning_lethality | 0.55583710 |
110 | MP0002090_abnormal_vision | 0.54614946 |
111 | MP0010768_mortality/aging | 0.54177809 |
112 | MP0005171_absent_coat_pigmentation | 0.52600964 |
113 | MP0004233_abnormal_muscle_weight | 0.52407631 |
114 | MP0003956_abnormal_body_size | 0.51810786 |
115 | MP0003938_abnormal_ear_development | 0.51747554 |
116 | MP0009379_abnormal_foot_pigmentation | 0.51209651 |
117 | MP0000681_abnormal_thyroid_gland | 0.50896680 |
118 | MP0008260_abnormal_autophagy | 0.50113344 |
119 | MP0001765_abnormal_ion_homeostasis | 0.49907207 |
120 | MP0004484_altered_response_of | 0.47431759 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Focal motor seizures (HP:0011153) | 7.22328251 |
2 | Myokymia (HP:0002411) | 7.16647431 |
3 | Focal seizures (HP:0007359) | 5.48106218 |
4 | Visual hallucinations (HP:0002367) | 5.41713114 |
5 | Atonic seizures (HP:0010819) | 4.67103574 |
6 | Epileptic encephalopathy (HP:0200134) | 4.64446253 |
7 | Progressive cerebellar ataxia (HP:0002073) | 4.50199388 |
8 | Febrile seizures (HP:0002373) | 4.14338328 |
9 | Absence seizures (HP:0002121) | 4.04331715 |
10 | Supranuclear gaze palsy (HP:0000605) | 3.98580458 |
11 | Action tremor (HP:0002345) | 3.97600319 |
12 | Dialeptic seizures (HP:0011146) | 3.74591184 |
13 | Generalized tonic-clonic seizures (HP:0002069) | 3.67119446 |
14 | Ankle clonus (HP:0011448) | 3.57358732 |
15 | Obstructive sleep apnea (HP:0002870) | 3.40186423 |
16 | Broad-based gait (HP:0002136) | 3.37965651 |
17 | Dysdiadochokinesis (HP:0002075) | 3.24430551 |
18 | Depression (HP:0000716) | 3.20656175 |
19 | Dysmetria (HP:0001310) | 3.19326498 |
20 | Cerebral hypomyelination (HP:0006808) | 3.15642308 |
21 | Gaze-evoked nystagmus (HP:0000640) | 3.15191349 |
22 | Anxiety (HP:0000739) | 3.13927912 |
23 | Neurofibrillary tangles (HP:0002185) | 3.10034552 |
24 | Mutism (HP:0002300) | 3.06842737 |
25 | Hyperthyroidism (HP:0000836) | 3.05877804 |
26 | Abnormal eating behavior (HP:0100738) | 3.05259163 |
27 | Poor eye contact (HP:0000817) | 3.00087915 |
28 | Amblyopia (HP:0000646) | 2.96906132 |
29 | Truncal ataxia (HP:0002078) | 2.94475513 |
30 | Hyperventilation (HP:0002883) | 2.93705902 |
31 | Scanning speech (HP:0002168) | 2.87194348 |
32 | Cerebral inclusion bodies (HP:0100314) | 2.83603969 |
33 | Tetraplegia (HP:0002445) | 2.82091060 |
34 | Impaired vibration sensation in the lower limbs (HP:0002166) | 2.79334848 |
35 | Impaired social interactions (HP:0000735) | 2.78137688 |
36 | Abnormal social behavior (HP:0012433) | 2.78137688 |
37 | Genetic anticipation (HP:0003743) | 2.75436771 |
38 | Limb dystonia (HP:0002451) | 2.75235282 |
39 | Pheochromocytoma (HP:0002666) | 2.74067936 |
40 | Spastic gait (HP:0002064) | 2.72822386 |
41 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.72463965 |
42 | Urinary urgency (HP:0000012) | 2.66418609 |
43 | Bundle branch block (HP:0011710) | 2.64399050 |
44 | Intention tremor (HP:0002080) | 2.64363938 |
45 | Progressive inability to walk (HP:0002505) | 2.62887670 |
46 | Truncus arteriosus (HP:0001660) | 2.58600560 |
47 | Hemiparesis (HP:0001269) | 2.57239430 |
48 | Abnormality of the corticospinal tract (HP:0002492) | 2.55608667 |
49 | Postural instability (HP:0002172) | 2.54645569 |
50 | Torticollis (HP:0000473) | 2.48792144 |
51 | Diplopia (HP:0000651) | 2.47938863 |
52 | Abnormality of binocular vision (HP:0011514) | 2.47938863 |
53 | Excessive salivation (HP:0003781) | 2.45089730 |
54 | Drooling (HP:0002307) | 2.45089730 |
55 | Focal dystonia (HP:0004373) | 2.42232885 |
56 | Neuroendocrine neoplasm (HP:0100634) | 2.40584531 |
57 | Apathy (HP:0000741) | 2.39662317 |
58 | Impaired smooth pursuit (HP:0007772) | 2.38053422 |
59 | Polyphagia (HP:0002591) | 2.36857620 |
60 | Ventricular fibrillation (HP:0001663) | 2.34123216 |
61 | Megalencephaly (HP:0001355) | 2.33819127 |
62 | Abnormality of the lower motor neuron (HP:0002366) | 2.32844180 |
63 | Papilledema (HP:0001085) | 2.31097856 |
64 | Hyperacusis (HP:0010780) | 2.26670454 |
65 | Pointed chin (HP:0000307) | 2.25143591 |
66 | Sleep apnea (HP:0010535) | 2.24450644 |
67 | Epileptiform EEG discharges (HP:0011182) | 2.23498681 |
68 | Heart block (HP:0012722) | 2.23386928 |
69 | Stereotypic behavior (HP:0000733) | 2.23084296 |
70 | Delusions (HP:0000746) | 2.22989362 |
71 | Insidious onset (HP:0003587) | 2.22147271 |
72 | Termporal pattern (HP:0011008) | 2.22147271 |
73 | Bradykinesia (HP:0002067) | 2.21809560 |
74 | Congenital malformation of the right heart (HP:0011723) | 2.19666644 |
75 | Double outlet right ventricle (HP:0001719) | 2.19666644 |
76 | Lower limb amyotrophy (HP:0007210) | 2.18726049 |
77 | Peripheral hypomyelination (HP:0007182) | 2.17413752 |
78 | EEG with generalized epileptiform discharges (HP:0011198) | 2.16991977 |
79 | Hemiplegia (HP:0002301) | 2.16470349 |
80 | Diminished motivation (HP:0000745) | 2.16080213 |
81 | Annular pancreas (HP:0001734) | 2.15240023 |
82 | Agitation (HP:0000713) | 2.15085938 |
83 | Hypercortisolism (HP:0001578) | 2.14761302 |
84 | Choreoathetosis (HP:0001266) | 2.14678514 |
85 | Fetal akinesia sequence (HP:0001989) | 2.14234229 |
86 | Craniofacial dystonia (HP:0012179) | 2.13232434 |
87 | Abnormal atrioventricular conduction (HP:0005150) | 2.12847521 |
88 | Failure to thrive in infancy (HP:0001531) | 2.12837592 |
89 | Psychosis (HP:0000709) | 2.12175308 |
90 | Generalized myoclonic seizures (HP:0002123) | 2.11610634 |
91 | Lower limb asymmetry (HP:0100559) | 2.10178972 |
92 | Hypsarrhythmia (HP:0002521) | 2.08182907 |
93 | Abnormality of ocular smooth pursuit (HP:0000617) | 2.05335890 |
94 | Absent speech (HP:0001344) | 2.05092330 |
95 | Lower limb muscle weakness (HP:0007340) | 2.04391038 |
96 | Amyotrophic lateral sclerosis (HP:0007354) | 2.04008708 |
97 | Spinal canal stenosis (HP:0003416) | 2.01083703 |
98 | Increased circulating renin level (HP:0000848) | 2.00192720 |
99 | Status epilepticus (HP:0002133) | 1.99806420 |
100 | Hypoventilation (HP:0002791) | 1.97404190 |
101 | Purpura (HP:0000979) | 1.96903822 |
102 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.96395233 |
103 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.96395233 |
104 | Generalized hypotonia (HP:0001290) | 1.96157105 |
105 | Insomnia (HP:0100785) | 1.93966302 |
106 | Inability to walk (HP:0002540) | 1.92993934 |
107 | Clonus (HP:0002169) | 1.92181442 |
108 | Akinesia (HP:0002304) | 1.90716210 |
109 | Gait ataxia (HP:0002066) | 1.90603403 |
110 | Specific learning disability (HP:0001328) | 1.90575712 |
111 | Dementia (HP:0000726) | 1.90297472 |
112 | Aqueductal stenosis (HP:0002410) | 1.88498324 |
113 | Turricephaly (HP:0000262) | 1.86771558 |
114 | Rapidly progressive (HP:0003678) | 1.85909274 |
115 | Dysmetric saccades (HP:0000641) | 1.84757734 |
116 | Incomplete penetrance (HP:0003829) | 1.83831568 |
117 | Foot dorsiflexor weakness (HP:0009027) | 1.82881457 |
118 | Narrow nasal bridge (HP:0000446) | 1.82830316 |
119 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.82736928 |
120 | Cholecystitis (HP:0001082) | 1.82508692 |
121 | Abnormal gallbladder physiology (HP:0012438) | 1.82508692 |
122 | Menorrhagia (HP:0000132) | 1.82020347 |
123 | Neuronal loss in central nervous system (HP:0002529) | 1.81941281 |
124 | Impaired vibratory sensation (HP:0002495) | 1.81749140 |
125 | Rigidity (HP:0002063) | 1.81596227 |
126 | Growth hormone excess (HP:0000845) | 1.80938265 |
127 | Distal upper limb amyotrophy (HP:0007149) | 1.80612115 |
128 | Upper limb amyotrophy (HP:0009129) | 1.80612115 |
129 | Abnormal EKG (HP:0003115) | 1.79345857 |
130 | Bowel incontinence (HP:0002607) | 1.77528699 |
131 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.76435736 |
132 | Aplasia of the phalanges of the hand (HP:0009802) | 1.76435736 |
133 | Aplasia involving bones of the extremities (HP:0009825) | 1.76435736 |
134 | Abnormality of saccadic eye movements (HP:0000570) | 1.74954539 |
135 | Retinal dysplasia (HP:0007973) | 1.74178272 |
136 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.73702179 |
137 | Atrioventricular block (HP:0001678) | 1.69935941 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NTRK3 | 4.06271632 |
2 | MAP3K9 | 4.05872190 |
3 | EPHA4 | 3.78367240 |
4 | MARK1 | 3.32529241 |
5 | MINK1 | 2.80726481 |
6 | MAP3K4 | 2.78289669 |
7 | MAP3K12 | 2.58527425 |
8 | MAP2K7 | 2.29587999 |
9 | DAPK2 | 2.24926759 |
10 | NTRK2 | 2.16781918 |
11 | PAK6 | 2.14934551 |
12 | PNCK | 2.00259037 |
13 | TRIB3 | 1.99873583 |
14 | MAP2K4 | 1.93947340 |
15 | KSR2 | 1.90487284 |
16 | CDK19 | 1.88258703 |
17 | NTRK1 | 1.78427411 |
18 | CASK | 1.78038255 |
19 | ARAF | 1.73198757 |
20 | GRK5 | 1.66751370 |
21 | UHMK1 | 1.60498465 |
22 | MAP3K11 | 1.59794099 |
23 | PRKD3 | 1.58278985 |
24 | CDK5 | 1.56448095 |
25 | CAMKK1 | 1.51180204 |
26 | RIPK4 | 1.50126994 |
27 | PRPF4B | 1.45462519 |
28 | KSR1 | 1.41450535 |
29 | PLK2 | 1.40385266 |
30 | TYRO3 | 1.36654734 |
31 | DAPK1 | 1.32824807 |
32 | MAPK13 | 1.31688896 |
33 | TNIK | 1.30684967 |
34 | PINK1 | 1.29200209 |
35 | OXSR1 | 1.27724042 |
36 | PRKCG | 1.23482436 |
37 | PHKG1 | 1.14838902 |
38 | PHKG2 | 1.14838902 |
39 | RIPK1 | 1.14465580 |
40 | STK38 | 1.10679796 |
41 | WNK1 | 1.09705716 |
42 | SMG1 | 1.09299344 |
43 | MAPK12 | 1.08764013 |
44 | MAP3K2 | 1.06761861 |
45 | FES | 1.06726705 |
46 | BRSK1 | 1.04269070 |
47 | CDK18 | 1.04215773 |
48 | SIK2 | 1.04085255 |
49 | CDK14 | 1.03150995 |
50 | CDK15 | 1.02036883 |
51 | CAMK2A | 1.01066997 |
52 | MAP3K13 | 0.99926698 |
53 | CAMKK2 | 0.99074806 |
54 | LATS2 | 0.99069786 |
55 | CAMK2B | 0.94010412 |
56 | SIK1 | 0.92932886 |
57 | CDK11A | 0.91545650 |
58 | SGK223 | 0.90371053 |
59 | SGK494 | 0.90371053 |
60 | CAMK1 | 0.89367045 |
61 | BMX | 0.88925087 |
62 | TAOK2 | 0.88305940 |
63 | BCR | 0.86856976 |
64 | STK11 | 0.83942062 |
65 | STK39 | 0.80009209 |
66 | ALK | 0.78625669 |
67 | NME1 | 0.78506505 |
68 | TESK1 | 0.78438834 |
69 | LIMK1 | 0.76540644 |
70 | CSNK1G2 | 0.74027867 |
71 | IRAK2 | 0.71785013 |
72 | PAK3 | 0.71568028 |
73 | DYRK1A | 0.70860730 |
74 | CAMK1D | 0.70570427 |
75 | PRKCH | 0.69177119 |
76 | TAOK1 | 0.68684034 |
77 | MARK2 | 0.68634423 |
78 | PKN2 | 0.67355430 |
79 | RET | 0.63715726 |
80 | FGR | 0.62776737 |
81 | CAMK2G | 0.62679862 |
82 | LMTK2 | 0.62184273 |
83 | MAP2K6 | 0.62083393 |
84 | CAMK4 | 0.59304093 |
85 | RAF1 | 0.58788963 |
86 | NEK6 | 0.58535188 |
87 | SGK1 | 0.58189486 |
88 | DMPK | 0.58105021 |
89 | BMPR2 | 0.57547975 |
90 | PDPK1 | 0.57053262 |
91 | CAMK2D | 0.56762739 |
92 | PTK2B | 0.55766166 |
93 | TNK2 | 0.54920857 |
94 | PRKCE | 0.53919437 |
95 | ROCK2 | 0.52426470 |
96 | PRKG2 | 0.51581248 |
97 | MAP3K1 | 0.50346751 |
98 | CDC42BPA | 0.50036196 |
99 | PDK1 | 0.49767846 |
100 | PRKCZ | 0.49090443 |
101 | PKN1 | 0.49010500 |
102 | CAMK1G | 0.46330867 |
103 | SGK2 | 0.45445169 |
104 | BRAF | 0.44987737 |
105 | MAPKAPK5 | 0.44666469 |
106 | DAPK3 | 0.44439843 |
107 | RPS6KA3 | 0.43923329 |
108 | PRKD2 | 0.43149363 |
109 | FER | 0.42584925 |
110 | MAP2K1 | 0.42298006 |
111 | FYN | 0.42087333 |
112 | MAP2K2 | 0.41655312 |
113 | MAPK10 | 0.40478081 |
114 | FGFR2 | 0.40343439 |
115 | MUSK | 0.39941788 |
116 | ADRBK1 | 0.39301687 |
117 | ICK | 0.38485761 |
118 | RPS6KA2 | 0.38198556 |
119 | SGK3 | 0.37251784 |
120 | WNK3 | 0.37135002 |
121 | PRKCI | 0.37123089 |
122 | HIPK2 | 0.36584053 |
123 | DYRK2 | 0.36569952 |
124 | GRK7 | 0.36479106 |
125 | PAK1 | 0.35093224 |
126 | ILK | 0.34329384 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nicotine addiction_Homo sapiens_hsa05033 | 3.80472397 |
2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.61015890 |
3 | GABAergic synapse_Homo sapiens_hsa04727 | 2.80883122 |
4 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 2.67492856 |
5 | Olfactory transduction_Homo sapiens_hsa04740 | 2.64606814 |
6 | Circadian entrainment_Homo sapiens_hsa04713 | 2.61715795 |
7 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.61528108 |
8 | Long-term potentiation_Homo sapiens_hsa04720 | 2.54875207 |
9 | Morphine addiction_Homo sapiens_hsa05032 | 2.46364844 |
10 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.37836882 |
11 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 2.31863310 |
12 | Dopaminergic synapse_Homo sapiens_hsa04728 | 2.17726179 |
13 | Salivary secretion_Homo sapiens_hsa04970 | 2.12460815 |
14 | Insulin secretion_Homo sapiens_hsa04911 | 1.90442221 |
15 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.87315944 |
16 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.86773020 |
17 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.83965899 |
18 | Taste transduction_Homo sapiens_hsa04742 | 1.83811318 |
19 | Long-term depression_Homo sapiens_hsa04730 | 1.82121423 |
20 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.77436676 |
21 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.74477135 |
22 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.71234974 |
23 | Cocaine addiction_Homo sapiens_hsa05030 | 1.70375937 |
24 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.70074643 |
25 | Renin secretion_Homo sapiens_hsa04924 | 1.60197806 |
26 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.60081871 |
27 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.55030651 |
28 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.49387263 |
29 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.44610941 |
30 | Gap junction_Homo sapiens_hsa04540 | 1.43363997 |
31 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.34434793 |
32 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 1.30974750 |
33 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.27000175 |
34 | Axon guidance_Homo sapiens_hsa04360 | 1.26116361 |
35 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.21834132 |
36 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.15788564 |
37 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.15508092 |
38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.09796674 |
39 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.09405100 |
40 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.08883444 |
41 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.08541400 |
42 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.08052008 |
43 | Melanogenesis_Homo sapiens_hsa04916 | 1.07617116 |
44 | Phototransduction_Homo sapiens_hsa04744 | 1.03917162 |
45 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.03244962 |
46 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 1.03243693 |
47 | Glioma_Homo sapiens_hsa05214 | 0.98354521 |
48 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.96236381 |
49 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.95873026 |
50 | Alzheimers disease_Homo sapiens_hsa05010 | 0.95828953 |
51 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.91680082 |
52 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.90392212 |
53 | Parkinsons disease_Homo sapiens_hsa05012 | 0.88113480 |
54 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.86151909 |
55 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.85943572 |
56 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.85726214 |
57 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.85529440 |
58 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.84410154 |
59 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.80779319 |
60 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.77352635 |
61 | Sulfur relay system_Homo sapiens_hsa04122 | 0.77119270 |
62 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.72395837 |
63 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.68996496 |
64 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.67671749 |
65 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.66064758 |
66 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.63767994 |
67 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.62863294 |
68 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.60844455 |
69 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.60054263 |
70 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.59608874 |
71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59459533 |
72 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.56690243 |
73 | Alcoholism_Homo sapiens_hsa05034 | 0.56222921 |
74 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55470958 |
75 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.55369861 |
76 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.55233326 |
77 | Endocytosis_Homo sapiens_hsa04144 | 0.55114977 |
78 | Huntingtons disease_Homo sapiens_hsa05016 | 0.54203231 |
79 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.50954585 |
80 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.50288189 |
81 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.49542954 |
82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.47530034 |
83 | Prion diseases_Homo sapiens_hsa05020 | 0.46738614 |
84 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.46545162 |
85 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.45667670 |
86 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.45480316 |
87 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.44931460 |
88 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.44826633 |
89 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.43178604 |
90 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.42980459 |
91 | Platelet activation_Homo sapiens_hsa04611 | 0.41710075 |
92 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.38631254 |
93 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.38544352 |
94 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.38037278 |
95 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.37719963 |
96 | Bile secretion_Homo sapiens_hsa04976 | 0.37608460 |
97 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.37510302 |
98 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.37135961 |
99 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.36962309 |
100 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.35366451 |
101 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.35342484 |
102 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.35328121 |
103 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.35321003 |
104 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.35271621 |
105 | Circadian rhythm_Homo sapiens_hsa04710 | 0.33484606 |
106 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.32642715 |
107 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.30837753 |
108 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.30684323 |
109 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.30434388 |
110 | Endometrial cancer_Homo sapiens_hsa05213 | 0.29773690 |
111 | Tight junction_Homo sapiens_hsa04530 | 0.29681768 |
112 | Histidine metabolism_Homo sapiens_hsa00340 | 0.29219752 |
113 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.29136194 |
114 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.28454304 |
115 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.28134818 |
116 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.27870303 |
117 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.27711643 |
118 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.25892240 |