RNF219

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.25166167
2mitotic sister chromatid cohesion (GO:0007064)4.13967373
3DNA strand elongation involved in DNA replication (GO:0006271)3.87165309
4kinetochore organization (GO:0051383)3.83165720
5protein localization to kinetochore (GO:0034501)3.74125578
6DNA strand elongation (GO:0022616)3.74124522
7negative regulation of DNA recombination (GO:0045910)3.72922918
8centriole replication (GO:0007099)3.70391923
9resolution of meiotic recombination intermediates (GO:0000712)3.67385242
10somatic hypermutation of immunoglobulin genes (GO:0016446)3.67290596
11somatic diversification of immune receptors via somatic mutation (GO:0002566)3.67290596
12negative regulation of DNA-dependent DNA replication (GO:2000104)3.64808365
13telomere maintenance via semi-conservative replication (GO:0032201)3.61363813
14piRNA metabolic process (GO:0034587)3.59605420
15CENP-A containing nucleosome assembly (GO:0034080)3.56737982
16synapsis (GO:0007129)3.56285637
17mitotic recombination (GO:0006312)3.53175468
18telomere maintenance via recombination (GO:0000722)3.44265073
19DNA damage response, detection of DNA damage (GO:0042769)3.41597297
20chromatin remodeling at centromere (GO:0031055)3.41228030
21regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.38754584
22mitotic metaphase plate congression (GO:0007080)3.37451011
23double-strand break repair via nonhomologous end joining (GO:0006303)3.37074467
24non-recombinational repair (GO:0000726)3.37074467
25DNA replication-independent nucleosome assembly (GO:0006336)3.34905454
26DNA replication-independent nucleosome organization (GO:0034724)3.34905454
27establishment of integrated proviral latency (GO:0075713)3.34445693
28DNA double-strand break processing (GO:0000729)3.31638424
29DNA replication-dependent nucleosome organization (GO:0034723)3.31523359
30DNA replication-dependent nucleosome assembly (GO:0006335)3.31523359
31regulation of double-strand break repair via homologous recombination (GO:0010569)3.31344243
32kinetochore assembly (GO:0051382)3.30632559
33DNA replication initiation (GO:0006270)3.30444397
34microtubule depolymerization (GO:0007019)3.30082742
35regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.28216499
36regulation of helicase activity (GO:0051095)3.27589367
37nucleotide-excision repair, DNA gap filling (GO:0006297)3.26754422
38positive regulation of cell cycle checkpoint (GO:1901978)3.20767583
39ribosome assembly (GO:0042255)3.20733427
40metaphase plate congression (GO:0051310)3.20444162
41regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.20395910
42regulation of mitotic spindle checkpoint (GO:1903504)3.20395910
43DNA replication checkpoint (GO:0000076)3.18467710
44protein localization to chromosome, centromeric region (GO:0071459)3.17777010
45mitotic nuclear envelope disassembly (GO:0007077)3.16329550
46sister chromatid segregation (GO:0000819)3.16055577
47negative regulation of RNA splicing (GO:0033119)3.13870884
48regulation of DNA endoreduplication (GO:0032875)3.12391012
49DNA topological change (GO:0006265)3.11218492
50pore complex assembly (GO:0046931)3.11145845
51attachment of spindle microtubules to kinetochore (GO:0008608)3.09604668
52telomere maintenance via telomere lengthening (GO:0010833)3.08588740
53establishment of chromosome localization (GO:0051303)3.04854242
54proteasome assembly (GO:0043248)3.04038472
55purine nucleobase biosynthetic process (GO:0009113)3.02385338
56mitotic sister chromatid segregation (GO:0000070)3.01367461
57replication fork processing (GO:0031297)3.01072732
58negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.00143169
59ribosomal small subunit assembly (GO:0000028)2.99425878
60nuclear pore organization (GO:0006999)2.98761065
61IMP biosynthetic process (GO:0006188)2.98006616
62regulation of sister chromatid cohesion (GO:0007063)2.97958991
63translesion synthesis (GO:0019985)2.97161280
64establishment of viral latency (GO:0019043)2.96227026
65spliceosomal complex assembly (GO:0000245)2.96226319
66histone exchange (GO:0043486)2.94725262
67histone mRNA metabolic process (GO:0008334)2.93486813
68centriole assembly (GO:0098534)2.92168526
69meiotic chromosome segregation (GO:0045132)2.91479338
70membrane disassembly (GO:0030397)2.91459342
71nuclear envelope disassembly (GO:0051081)2.91459342
72maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.90870960
73nuclear pore complex assembly (GO:0051292)2.87934562
74mitotic chromosome condensation (GO:0007076)2.87715607
75ATP-dependent chromatin remodeling (GO:0043044)2.87546871
76organelle disassembly (GO:1903008)2.84582841
77sister chromatid cohesion (GO:0007062)2.82503830
78histone H2A acetylation (GO:0043968)2.81137365
79DNA ligation (GO:0006266)2.79676984
80mitotic G2/M transition checkpoint (GO:0044818)2.78429778
81negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.76054797
82negative regulation of sister chromatid segregation (GO:0033046)2.76054797
83negative regulation of mitotic sister chromatid separation (GO:2000816)2.76054797
84negative regulation of mitotic sister chromatid segregation (GO:0033048)2.76054797
85cullin deneddylation (GO:0010388)2.74895719
86spindle assembly checkpoint (GO:0071173)2.74181308
87negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.73956397
88positive regulation of histone H3-K4 methylation (GO:0051571)2.72887370
89negative regulation of chromosome segregation (GO:0051985)2.72119851
90spindle checkpoint (GO:0031577)2.70727438
91mitotic spindle assembly checkpoint (GO:0007094)2.69907819
92exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.67902617
93regulation of mitotic metaphase/anaphase transition (GO:0030071)2.67016968
94chromatin assembly or disassembly (GO:0006333)2.66089042
95regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.65600882
96chromosome segregation (GO:0007059)2.65266579
97telomere maintenance (GO:0000723)2.62652045
98mRNA splicing, via spliceosome (GO:0000398)2.62605824
99RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.62605824
100RNA splicing, via transesterification reactions (GO:0000375)2.61414951
101DNA catabolic process, exonucleolytic (GO:0000738)2.61274870
102telomere organization (GO:0032200)2.61017833
103nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.60386545
104regulation of centriole replication (GO:0046599)2.60020976
105regulation of sister chromatid segregation (GO:0033045)2.59821788
106regulation of mitotic sister chromatid separation (GO:0010965)2.59821788
107regulation of mitotic sister chromatid segregation (GO:0033047)2.59821788
108alternative mRNA splicing, via spliceosome (GO:0000380)2.59242848
109RNA-dependent DNA replication (GO:0006278)2.58741835
110regulation of protein heterodimerization activity (GO:0043497)2.58675687
111base-excision repair (GO:0006284)2.58419693
112DNA duplex unwinding (GO:0032508)2.57950975
113mitotic spindle checkpoint (GO:0071174)2.57583659
114protein localization to chromosome (GO:0034502)2.57525949
115regulation of telomere maintenance (GO:0032204)2.56910053
116DNA geometric change (GO:0032392)2.55968794
117spliceosomal snRNP assembly (GO:0000387)2.55849217
118postreplication repair (GO:0006301)2.55546725
119regulation of chromosome segregation (GO:0051983)2.55267595
120maturation of SSU-rRNA (GO:0030490)2.55135564
121mRNA splice site selection (GO:0006376)2.53625909
122viral mRNA export from host cell nucleus (GO:0046784)2.52719455
123regulation of spindle organization (GO:0090224)2.52525926
124pre-miRNA processing (GO:0031054)2.51763111
125negative regulation of mRNA processing (GO:0050686)2.51574160
126termination of RNA polymerase II transcription (GO:0006369)2.49715070
127regulation of histone H3-K9 methylation (GO:0051570)2.49425202
128deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.47807182
129formation of translation preinitiation complex (GO:0001731)2.45978450
130intra-S DNA damage checkpoint (GO:0031573)2.45387663

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F4_17652178_ChIP-ChIP_JURKAT_Human4.45493462
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.31974262
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.73255507
4FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.50348574
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.13989837
6RBPJ_22232070_ChIP-Seq_NCS_Mouse2.96261841
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.94973420
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.80636254
9TP63_19390658_ChIP-ChIP_HaCaT_Human2.74779196
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.64642758
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.59118306
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.48954559
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.44136860
14EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.42497198
15E2F1_21310950_ChIP-Seq_MCF-7_Human2.42391484
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.32862304
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.31329856
18KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.20512343
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.14610440
20ELK1_19687146_ChIP-ChIP_HELA_Human2.13978569
21MYC_19079543_ChIP-ChIP_MESCs_Mouse2.13021529
22POU3F2_20337985_ChIP-ChIP_501MEL_Human2.12177640
23YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.06709463
24XRN2_22483619_ChIP-Seq_HELA_Human2.03559561
25EGR1_19374776_ChIP-ChIP_THP-1_Human2.01489710
26VDR_23849224_ChIP-Seq_CD4+_Human2.01043884
27E2F7_22180533_ChIP-Seq_HELA_Human10.2487581
28MYC_18358816_ChIP-ChIP_MESCs_Mouse1.98253452
29ZNF274_21170338_ChIP-Seq_K562_Hela1.95889404
30NELFA_20434984_ChIP-Seq_ESCs_Mouse1.94632128
31CIITA_25753668_ChIP-Seq_RAJI_Human1.93881866
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.93759155
33TTF2_22483619_ChIP-Seq_HELA_Human1.93675922
34FOXP3_21729870_ChIP-Seq_TREG_Human1.93318986
35TAF15_26573619_Chip-Seq_HEK293_Human1.91222861
36ETS1_20019798_ChIP-Seq_JURKAT_Human1.83043806
37CREB1_15753290_ChIP-ChIP_HEK293T_Human1.82178750
38JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.81145501
39* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.81090468
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.80452874
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79460513
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.71781161
43FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.71519219
44NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.68755561
45* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.68052477
46AR_21909140_ChIP-Seq_LNCAP_Human1.62922715
47THAP11_20581084_ChIP-Seq_MESCs_Mouse1.60739722
48MYCN_18555785_ChIP-Seq_MESCs_Mouse1.58705649
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.57718011
50* EWS_26573619_Chip-Seq_HEK293_Human1.55404097
51EZH2_22144423_ChIP-Seq_EOC_Human1.55180050
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.54070284
53GBX2_23144817_ChIP-Seq_PC3_Human1.53976877
54ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50635628
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.50302631
56MYC_22102868_ChIP-Seq_BL_Human1.47065935
57GABP_19822575_ChIP-Seq_HepG2_Human1.46840130
58* P300_19829295_ChIP-Seq_ESCs_Human1.41070482
59SALL1_21062744_ChIP-ChIP_HESCs_Human1.38115888
60ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.37932971
61MYC_18940864_ChIP-ChIP_HL60_Human1.36692166
62FUS_26573619_Chip-Seq_HEK293_Human1.36672820
63IRF1_19129219_ChIP-ChIP_H3396_Human1.34703007
64CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34420902
65CTBP2_25329375_ChIP-Seq_LNCAP_Human1.32905142
66PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32383464
67E2F1_18555785_ChIP-Seq_MESCs_Mouse1.31988954
68HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.30919894
69DCP1A_22483619_ChIP-Seq_HELA_Human1.28573571
70POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.27328712
71CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.25423132
72CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25310888
73ZFX_18555785_ChIP-Seq_MESCs_Mouse1.24167649
74ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.23957056
75SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.22564372
76GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.21041067
77YY1_21170310_ChIP-Seq_MESCs_Mouse1.20356873
78FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.19627671
79ERG_20887958_ChIP-Seq_HPC-7_Mouse1.17094571
80NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.16947589
81RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.16579292
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14751491
83POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12834375
84* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.11115400
85SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.10863174
86MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.10246343
87SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.09922600
88* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.08006453
89VDR_22108803_ChIP-Seq_LS180_Human1.04515225
90UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.03504697
91FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.03121406
92SRF_21415370_ChIP-Seq_HL-1_Mouse1.02718155
93OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01724291
94SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01210886
95TOP2B_26459242_ChIP-Seq_MCF-7_Human1.01143251
96FLI1_27457419_Chip-Seq_LIVER_Mouse1.01099920
97SOX2_16153702_ChIP-ChIP_HESCs_Human1.00251740
98MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.00127419
99KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96296609
100IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96099522
101CBP_20019798_ChIP-Seq_JUKART_Human0.96099522
102CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95216367
103SCL_19346495_ChIP-Seq_HPC-7_Human0.93469864
104SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.93327064
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.93049780
106KDM5A_27292631_Chip-Seq_BREAST_Human0.92669301
107FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92201692
108POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.91510485
109WT1_19549856_ChIP-ChIP_CCG9911_Human0.90697275
110CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.90414425
111IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.89125384
112IGF1R_20145208_ChIP-Seq_DFB_Human0.88257563
113GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.87583784
114AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.87361292
115PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.86571419
116CBX2_27304074_Chip-Seq_ESCs_Mouse0.86304692
117SPI1_23547873_ChIP-Seq_NB4_Human0.86177545
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.84840137
119DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.84645734
120* VDR_21846776_ChIP-Seq_THP-1_Human0.82770453
121PKCTHETA_26484144_Chip-Seq_BREAST_Human0.82341429
122CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.82197581
123ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.78371013
124PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.76048102
125CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.72143310
126* MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.71910721
127NANOG_16153702_ChIP-ChIP_HESCs_Human0.69831676
128RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.67520517
129RNF2_27304074_Chip-Seq_NSC_Mouse0.66478910
130CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.61982831
131DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.61736160
132MYB_26560356_Chip-Seq_TH2_Human0.61433301
133BMI1_23680149_ChIP-Seq_NPCS_Mouse0.59703319

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0010094_abnormal_chromosome_stability3.64614144
2MP0008057_abnormal_DNA_replication3.59742844
3MP0003123_paternal_imprinting3.03973211
4MP0003693_abnormal_embryo_hatching2.98419721
5MP0003121_genomic_imprinting2.90384792
6MP0003077_abnormal_cell_cycle2.84783168
7MP0003111_abnormal_nucleus_morphology2.76296058
8MP0002396_abnormal_hematopoietic_system2.69006434
9MP0008058_abnormal_DNA_repair2.67738306
10MP0008007_abnormal_cellular_replicative2.47673741
11MP0003718_maternal_effect2.44385779
12MP0001529_abnormal_vocalization2.43448534
13MP0006292_abnormal_olfactory_placode2.36710139
14MP0004957_abnormal_blastocyst_morpholog2.35922563
15MP0008877_abnormal_DNA_methylation2.24951775
16MP0003787_abnormal_imprinting2.10327200
17MP0002938_white_spotting1.95437449
18MP0003122_maternal_imprinting1.92694498
19MP0008932_abnormal_embryonic_tissue1.88221214
20MP0010030_abnormal_orbit_morphology1.85331590
21MP0004808_abnormal_hematopoietic_stem1.82675083
22MP0000537_abnormal_urethra_morphology1.76218077
23MP0002102_abnormal_ear_morphology1.75447616
24MP0000778_abnormal_nervous_system1.64038144
25MP0001293_anophthalmia1.62848767
26MP0003880_abnormal_central_pattern1.59936200
27MP0003221_abnormal_cardiomyocyte_apopto1.58018723
28MP0000350_abnormal_cell_proliferation1.57327685
29MP0001984_abnormal_olfaction1.56153946
30MP0000566_synostosis1.55824866
31MP0005187_abnormal_penis_morphology1.54401164
32MP0000049_abnormal_middle_ear1.49104086
33MP0002163_abnormal_gland_morphology1.48913605
34MP0001929_abnormal_gametogenesis1.47518826
35MP0003943_abnormal_hepatobiliary_system1.42350044
36MP0003763_abnormal_thymus_physiology1.41167516
37MP0001188_hyperpigmentation1.37050584
38MP0009250_abnormal_appendicular_skeleto1.34131729
39MP0003937_abnormal_limbs/digits/tail_de1.32379773
40MP0005174_abnormal_tail_pigmentation1.28501989
41MP0003385_abnormal_body_wall1.27830196
42MP0003315_abnormal_perineum_morphology1.27246156
43MP0006072_abnormal_retinal_apoptosis1.24752328
44MP0008789_abnormal_olfactory_epithelium1.21257076
45MP0000490_abnormal_crypts_of1.21115526
46MP0002751_abnormal_autonomic_nervous1.20853426
47MP0002932_abnormal_joint_morphology1.20641086
48MP0003942_abnormal_urinary_system1.19721828
49MP0000516_abnormal_urinary_system1.19028075
50MP0005367_renal/urinary_system_phenotyp1.19028075
51MP0002282_abnormal_trachea_morphology1.17881661
52MP0000703_abnormal_thymus_morphology1.17881007
53MP0001145_abnormal_male_reproductive1.17659551
54MP0006035_abnormal_mitochondrial_morpho1.17420481
55MP0000653_abnormal_sex_gland1.15453605
56MP0001697_abnormal_embryo_size1.14975633
57MP0001730_embryonic_growth_arrest1.14963317
58MP0002234_abnormal_pharynx_morphology1.14703270
59MP0003890_abnormal_embryonic-extraembry1.14520986
60MP0009053_abnormal_anal_canal1.12707266
61MP0002085_abnormal_embryonic_tissue1.12256643
62MP0002249_abnormal_larynx_morphology1.12187774
63MP0002095_abnormal_skin_pigmentation1.09899067
64MP0002697_abnormal_eye_size1.08668606
65MP0002084_abnormal_developmental_patter1.07639750
66MP0003698_abnormal_male_reproductive1.07560166
67MP0008995_early_reproductive_senescence1.07064356
68MP0000569_abnormal_digit_pigmentation1.06193567
69MP0004197_abnormal_fetal_growth/weight/1.05554856
70MP0002398_abnormal_bone_marrow1.05236445
71MP0001672_abnormal_embryogenesis/_devel1.03802200
72MP0005380_embryogenesis_phenotype1.03802200
73MP0010307_abnormal_tumor_latency1.02391225
74MP0000313_abnormal_cell_death1.00935424
75MP0003136_yellow_coat_color0.98762958
76MP0009697_abnormal_copulation0.98347026
77MP0003935_abnormal_craniofacial_develop0.97839685
78MP0002114_abnormal_axial_skeleton0.97412080
79MP0003786_premature_aging0.96990178
80MP0003984_embryonic_growth_retardation0.96710590
81MP0004215_abnormal_myocardial_fiber0.96391790
82MP0005391_vision/eye_phenotype0.95824132
83MP0002233_abnormal_nose_morphology0.94773367
84MP0000015_abnormal_ear_pigmentation0.94622020
85MP0002092_abnormal_eye_morphology0.94611120
86MP0002109_abnormal_limb_morphology0.94389202
87MP0001299_abnormal_eye_distance/0.94074230
88MP0002210_abnormal_sex_determination0.93760156
89MP0002088_abnormal_embryonic_growth/wei0.93237557
90MP0003755_abnormal_palate_morphology0.93088447
91MP0003938_abnormal_ear_development0.92821748
92MP0005084_abnormal_gallbladder_morpholo0.92772715
93MP0002116_abnormal_craniofacial_bone0.92733588
94MP0006276_abnormal_autonomic_nervous0.92571325
95MP0004811_abnormal_neuron_physiology0.90901643
96MP0000678_abnormal_parathyroid_gland0.90754694
97MP0003567_abnormal_fetal_cardiomyocyte0.90730106
98MP0001119_abnormal_female_reproductive0.90675937
99MP0002019_abnormal_tumor_incidence0.90032051
100MP0005253_abnormal_eye_physiology0.89759277
101MP0005397_hematopoietic_system_phenotyp0.89043750
102MP0001545_abnormal_hematopoietic_system0.89043750
103MP0000631_abnormal_neuroendocrine_gland0.88283044
104MP0001286_abnormal_eye_development0.87964887
105MP0002177_abnormal_outer_ear0.87074094
106MP0000432_abnormal_head_morphology0.85581051
107MP0003941_abnormal_skin_development0.84292694
108MP0000647_abnormal_sebaceous_gland0.84168971
109MP0009703_decreased_birth_body0.83150075
110MP0002080_prenatal_lethality0.82590442
111MP0002086_abnormal_extraembryonic_tissu0.82203573
112MP0002722_abnormal_immune_system0.81567051
113MP0000428_abnormal_craniofacial_morphol0.80774221
114MP0009672_abnormal_birth_weight0.80007692
115MP0001270_distended_abdomen0.79925126
116MP0005499_abnormal_olfactory_system0.79688536
117MP0005394_taste/olfaction_phenotype0.79688536
118MP0002161_abnormal_fertility/fecundity0.79154983
119MP0003861_abnormal_nervous_system0.77956728
120MP0000358_abnormal_cell_content/0.77096493
121MP0000465_gastrointestinal_hemorrhage0.77020137
122MP0001177_atelectasis0.74321324
123MP0006054_spinal_hemorrhage0.74203908
124MP0000689_abnormal_spleen_morphology0.73807888
125MP0003119_abnormal_digestive_system0.73167240
126MP0002113_abnormal_skeleton_development0.72432241
127MP0002081_perinatal_lethality0.72293532
128MP0000372_irregular_coat_pigmentation0.72027015
129MP0002822_catalepsy0.71526129
130MP0002152_abnormal_brain_morphology0.71474632
131MP0002160_abnormal_reproductive_system0.71463191
132MP0002184_abnormal_innervation0.71131730
133MP0002009_preneoplasia0.71021338
134MP0002111_abnormal_tail_morphology0.70561160
135MP0000955_abnormal_spinal_cord0.70365625
136MP0009379_abnormal_foot_pigmentation0.70284224
137MP0005395_other_phenotype0.68991208
138MP0005248_abnormal_Harderian_gland0.68897036

Predicted human phenotypes

RankGene SetZ-score
1Volvulus (HP:0002580)3.88066197
2Abnormality of the labia minora (HP:0012880)3.79099414
3Chromsome breakage (HP:0040012)3.34459121
4Birth length less than 3rd percentile (HP:0003561)3.10777938
5Chromosomal breakage induced by crosslinking agents (HP:0003221)2.95909877
6Cortical dysplasia (HP:0002539)2.89809512
7Aplastic anemia (HP:0001915)2.78082922
8Abnormality of the ileum (HP:0001549)2.70795853
9Reticulocytopenia (HP:0001896)2.70708722
10Meckel diverticulum (HP:0002245)2.70341628
11Abnormality of chromosome stability (HP:0003220)2.65857030
12Abnormal number of incisors (HP:0011064)2.61991859
13Oligodactyly (hands) (HP:0001180)2.60543185
14Nephroblastoma (Wilms tumor) (HP:0002667)2.60271205
15Aplasia/Hypoplasia of the uvula (HP:0010293)2.59846076
16Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.59127699
17Short 4th metacarpal (HP:0010044)2.59127699
18Patellar aplasia (HP:0006443)2.56147550
19Abnormal lung lobation (HP:0002101)2.55884994
20Shoulder girdle muscle weakness (HP:0003547)2.49450546
21Colon cancer (HP:0003003)2.48620446
22Embryonal renal neoplasm (HP:0011794)2.46927007
23Medulloblastoma (HP:0002885)2.43881780
24Increased nuchal translucency (HP:0010880)2.38417677
25Abnormality of the preputium (HP:0100587)2.35918126
26Aplasia/Hypoplasia of the patella (HP:0006498)2.35431164
27Small intestinal stenosis (HP:0012848)2.34868007
28Duodenal stenosis (HP:0100867)2.34868007
29Intestinal atresia (HP:0011100)2.31513332
30Myelodysplasia (HP:0002863)2.30253762
31Abnormal number of erythroid precursors (HP:0012131)2.28936636
32Ectopic kidney (HP:0000086)2.27594857
33Hypoplastic pelvis (HP:0008839)2.27237398
34Optic nerve coloboma (HP:0000588)2.24774221
35Papillary thyroid carcinoma (HP:0002895)2.21747146
36Glioma (HP:0009733)2.19946396
37Median cleft lip (HP:0000161)2.19937319
38Abnormality of cells of the erythroid lineage (HP:0012130)2.18994154
39Ependymoma (HP:0002888)2.15805889
40Acute lymphatic leukemia (HP:0006721)2.15107951
41Oligodactyly (HP:0012165)2.13041108
4211 pairs of ribs (HP:0000878)2.11874929
43Septo-optic dysplasia (HP:0100842)2.09222584
44Long eyelashes (HP:0000527)2.08127104
45Abnormality of the astrocytes (HP:0100707)2.07250253
46Astrocytoma (HP:0009592)2.07250253
47Abnormality of the intervertebral disk (HP:0005108)2.05261675
48Deviation of the thumb (HP:0009603)2.03815263
49Acute myeloid leukemia (HP:0004808)2.01475374
50Absent radius (HP:0003974)1.99913012
51Gonadotropin excess (HP:0000837)1.99141457
52Optic nerve hypoplasia (HP:0000609)1.98383587
53Supernumerary spleens (HP:0009799)1.98311068
54Aplasia involving forearm bones (HP:0009822)1.97217732
55Absent forearm bone (HP:0003953)1.97217732
56Proximal placement of thumb (HP:0009623)1.96830265
57Medial flaring of the eyebrow (HP:0010747)1.95679723
58Abnormality of the incisor (HP:0000676)1.95550813
59Abnormal hair whorl (HP:0010721)1.94666762
60Drooling (HP:0002307)1.94495331
61Abnormality of the septum pellucidum (HP:0007375)1.94436400
62Renal cortical cysts (HP:0000803)1.94219361
63Abnormality of the hip-girdle musculature (HP:0001445)1.93322973
64Abnormality of the musculature of the pelvis (HP:0001469)1.93322973
65Congenital primary aphakia (HP:0007707)1.93112510
66Selective tooth agenesis (HP:0001592)1.92637594
67Broad palm (HP:0001169)1.92102348
68Aplasia/Hypoplasia of the sternum (HP:0006714)1.91344586
69Tented upper lip vermilion (HP:0010804)1.90188862
70Absent septum pellucidum (HP:0001331)1.90011269
71Bifid tongue (HP:0010297)1.89608963
72Severe visual impairment (HP:0001141)1.89360952
73Increased serum pyruvate (HP:0003542)1.89298614
74Microvesicular hepatic steatosis (HP:0001414)1.86209002
75Gait imbalance (HP:0002141)1.85285275
76Short tibia (HP:0005736)1.85088554
77Atresia of the external auditory canal (HP:0000413)1.84669663
78Abnormality of the phalanges of the hallux (HP:0010057)1.83445133
79Premature graying of hair (HP:0002216)1.83318591
80Deep philtrum (HP:0002002)1.82716588
81Neoplasm of the oral cavity (HP:0100649)1.82494538
82Capillary hemangiomas (HP:0005306)1.82297580
83Hepatoblastoma (HP:0002884)1.82257690
84Abnormality of the duodenum (HP:0002246)1.82196659
85Abnormality of the carotid arteries (HP:0005344)1.80938201
86Gastrointestinal atresia (HP:0002589)1.80185519
87IgM deficiency (HP:0002850)1.79081660
88Pelvic girdle muscle weakness (HP:0003749)1.78673937
89Abnormality of the metopic suture (HP:0005556)1.78399848
90Neoplasm of the colon (HP:0100273)1.77890551
91Sloping forehead (HP:0000340)1.77441676
92Agnosia (HP:0010524)1.76644702
93Methylmalonic acidemia (HP:0002912)1.75881285
94Genital tract atresia (HP:0001827)1.75452066
95Nephrogenic diabetes insipidus (HP:0009806)1.75442169
96Irregular epiphyses (HP:0010582)1.74760507
97Rhabdomyosarcoma (HP:0002859)1.74289525
98Hypoplasia of the capital femoral epiphysis (HP:0003090)1.73635224
99Aplasia/Hypoplasia of the tibia (HP:0005772)1.73289889
100Hyperglycinemia (HP:0002154)1.72646814
101Metaphyseal dysplasia (HP:0100255)1.72426720
102Dislocated radial head (HP:0003083)1.72222768
103Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.71600190
104Heterochromia iridis (HP:0001100)1.71234917
105Overlapping toe (HP:0001845)1.71169272
106Abnormality of the fingertips (HP:0001211)1.70398828
107Excessive salivation (HP:0003781)1.70321054
108Midline defect of the nose (HP:0004122)1.70295934
109Abnormality of DNA repair (HP:0003254)1.70290277
110Short middle phalanx of the 5th finger (HP:0004220)1.69737798
111Type 2 muscle fiber atrophy (HP:0003554)1.69670507
112Abnormality of the anterior horn cell (HP:0006802)1.69640256
113Degeneration of anterior horn cells (HP:0002398)1.69640256
114Rimmed vacuoles (HP:0003805)1.68628675
115Abnormality of the columella (HP:0009929)1.68430542
116Muscle fiber atrophy (HP:0100295)1.67759696
117Pendular nystagmus (HP:0012043)1.67614123
118Diastasis recti (HP:0001540)1.66668666
119Vaginal atresia (HP:0000148)1.66542812
120Triphalangeal thumb (HP:0001199)1.66102545
121Abnormality of the radial head (HP:0003995)1.66008926
122Patchy hypopigmentation of hair (HP:0011365)1.65949181
123High anterior hairline (HP:0009890)1.63452489
124Morphological abnormality of the middle ear (HP:0008609)1.62951772
125Stenosis of the external auditory canal (HP:0000402)1.62253518
126Clubbing of toes (HP:0100760)1.61821961
127Neoplasm of the small intestine (HP:0100833)1.61611825
128Facial hemangioma (HP:0000329)1.61294946
129Renal duplication (HP:0000075)1.61109846
130Preaxial hand polydactyly (HP:0001177)1.61059142
131Abnormality of midbrain morphology (HP:0002418)1.60900845
132Molar tooth sign on MRI (HP:0002419)1.60900845
133Slender long bone (HP:0003100)1.60368115
134Postnatal microcephaly (HP:0005484)1.60263021
135Abnormality of glycolysis (HP:0004366)1.59975585
136Microtia (HP:0008551)1.59899530
137Astigmatism (HP:0000483)1.58855516
138Abnormality of chromosome segregation (HP:0002916)1.58621489
139Sensory axonal neuropathy (HP:0003390)1.58455878
140Arteriovenous malformation (HP:0100026)1.57740469
141Micropenis (HP:0000054)1.57477274
142Bone marrow hypocellularity (HP:0005528)1.57411948
143Broad phalanges of the hand (HP:0009768)1.55794648
144Progressive inability to walk (HP:0002505)1.55739562
145Anencephaly (HP:0002323)1.55563603
146Trigonocephaly (HP:0000243)1.55002507
147Abnormality of the 4th metacarpal (HP:0010012)1.54996030
148Increased number of teeth (HP:0011069)1.54868279
149Renal dysplasia (HP:0000110)1.54778995
150Abnormality of the renal collecting system (HP:0004742)1.54410334
151Retinal dysplasia (HP:0007973)1.54207137
152Decreased lacrimation (HP:0000633)1.53976117
153Abnormality of the parietal bone (HP:0002696)1.53017100
154Spinal cord lesions (HP:0100561)1.52718941
155Syringomyelia (HP:0003396)1.52718941
156Prominent metopic ridge (HP:0005487)1.52640769
157Broad finger (HP:0001500)1.52436957
158Lissencephaly (HP:0001339)1.51896017
159Embryonal neoplasm (HP:0002898)1.51764424
160Pallor (HP:0000980)1.51752181
161True hermaphroditism (HP:0010459)1.51684289
162Postaxial hand polydactyly (HP:0001162)1.51496143
163Congenital diaphragmatic hernia (HP:0000776)1.50278051
164Absent thumb (HP:0009777)1.49379732
165Thyroid carcinoma (HP:0002890)1.49135977
166Prominent nose (HP:0000448)1.48525059
167Horseshoe kidney (HP:0000085)1.48205978

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC74.89363594
2SRPK13.35910353
3VRK13.10618651
4STK163.08913673
5TRIM283.07253548
6SIK32.87390058
7MKNK12.51348045
8PNCK2.42379331
9PLK42.17709870
10EIF2AK12.07911087
11CDK82.06905506
12WNK32.01160197
13TSSK61.97240925
14WEE11.97157993
15CDK121.94443800
16PLK31.89491887
17CCNB11.89329537
18BUB11.87907246
19PBK1.87108708
20ATR1.86512451
21EEF2K1.86495000
22ACVR1B1.81622701
23MKNK21.76124546
24TAOK21.63005675
25RPS6KA41.54712675
26MAP3K121.53556606
27TGFBR11.51980657
28CDK71.46039250
29TXK1.40741105
30PLK11.40419638
31NEK21.40242927
32CHEK21.39829401
33BRSK21.37651094
34MAPK131.37512744
35CSNK1G21.35467442
36ERBB31.33766069
37PRPF4B1.32234393
38MAP4K11.31346142
39STK241.29140290
40BRD41.28814172
41TTK1.27392537
42PASK1.26694916
43TAF11.26174309
44PINK11.25763835
45MST41.25357836
46NUAK11.24381826
47AURKB1.21501080
48PAK41.15471062
49CHEK11.14954145
50MARK11.12106431
51STK101.09800270
52CASK1.04095103
53STK31.03728183
54ATM1.03534597
55PIM21.02709453
56BTK0.99982569
57CDK190.94154025
58PLK20.93804920
59ZAK0.92818190
60VRK20.92016392
61TEC0.91910353
62EPHA40.91108533
63YES10.88071020
64EIF2AK30.86457841
65MAP2K70.83720542
66CDK40.83266817
67DYRK30.82696551
68KSR10.82031863
69EPHA30.77323476
70RPS6KB20.75275641
71KIT0.74784018
72DAPK10.73322166
73MAP3K40.73040604
74MINK10.70715414
75STK40.69156393
76CSF1R0.68500374
77PIM10.68412280
78CDK20.68376253
79LATS10.67331896
80CDK10.66344408
81UHMK10.65081387
82SCYL20.65077980
83MUSK0.63301551
84CDK90.63166584
85TAOK30.60298627
86DYRK20.60062362
87TNIK0.59081362
88SIK20.59027354
89BRSK10.58606607
90CDK140.58294422
91CDK60.56691661
92CSNK1E0.55812129
93CSNK1G30.54889568
94AURKA0.54668573
95MAP3K60.54244618
96STK390.54005646
97CDK180.53489361
98NEK10.51898130
99MAP3K90.50814678
100RPS6KA50.49488444
101STK38L0.48090174
102MAP3K80.47973541
103CSNK2A20.47509381
104DYRK1A0.47059898
105NME10.46566708
106CSNK2A10.46258759
107RPS6KB10.46239888
108EIF2AK20.45778801
109CLK10.45489660
110CDK150.45220295
111BCR0.44778205
112FGFR10.44534952
113PRKCG0.44461532
114MAP3K100.44242447
115OXSR10.43877447
116CDK11A0.43008801
117MAP4K20.41683644
118MELK0.40824353
119CSNK1D0.39771291
120NTRK20.39025230
121TNK20.38806746
122PDK20.38508676
123LYN0.37820182
124MAPK140.37689324
125PRKDC0.36911093
126MATK0.36149253
127BMPR1B0.35952909
128SGK20.35857551
129CSNK1G10.35843177
130CSNK1A1L0.35351219
131MAP2K40.35245152
132CDK30.35174439
133CHUK0.34790181
134ERBB40.34786965
135MAP3K50.34705863
136FRK0.34342726
137SYK0.32932947

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.11158954
2Mismatch repair_Homo sapiens_hsa034303.26005132
3Spliceosome_Homo sapiens_hsa030402.89584765
4Cell cycle_Homo sapiens_hsa041102.83648090
5Base excision repair_Homo sapiens_hsa034102.80449027
6Homologous recombination_Homo sapiens_hsa034402.51233625
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.37305032
8RNA transport_Homo sapiens_hsa030132.36585268
9Nucleotide excision repair_Homo sapiens_hsa034202.36152392
10Fanconi anemia pathway_Homo sapiens_hsa034602.30278599
11Ribosome_Homo sapiens_hsa030102.22073468
12Non-homologous end-joining_Homo sapiens_hsa034502.21711167
13RNA degradation_Homo sapiens_hsa030182.17209873
14Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.98966019
15RNA polymerase_Homo sapiens_hsa030201.90596472
16mRNA surveillance pathway_Homo sapiens_hsa030151.77213109
17Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.75171792
18Proteasome_Homo sapiens_hsa030501.72789712
19Basal transcription factors_Homo sapiens_hsa030221.67933850
20Propanoate metabolism_Homo sapiens_hsa006401.62117067
21Pyrimidine metabolism_Homo sapiens_hsa002401.57255083
22Steroid biosynthesis_Homo sapiens_hsa001001.56675042
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.39676795
24p53 signaling pathway_Homo sapiens_hsa041151.33735971
25Cysteine and methionine metabolism_Homo sapiens_hsa002701.30156786
26Folate biosynthesis_Homo sapiens_hsa007901.26461763
27Parkinsons disease_Homo sapiens_hsa050121.26455304
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.22322233
29One carbon pool by folate_Homo sapiens_hsa006701.19930526
30Colorectal cancer_Homo sapiens_hsa052101.17625015
31Selenocompound metabolism_Homo sapiens_hsa004501.16740240
32Epstein-Barr virus infection_Homo sapiens_hsa051691.16080296
33Oocyte meiosis_Homo sapiens_hsa041141.15432114
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.14773860
35Transcriptional misregulation in cancer_Homo sapiens_hsa052021.12245119
36Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.11382268
37Nicotine addiction_Homo sapiens_hsa050331.08151706
38Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.07978159
39Fatty acid elongation_Homo sapiens_hsa000621.07957367
40MicroRNAs in cancer_Homo sapiens_hsa052061.06548530
41Circadian rhythm_Homo sapiens_hsa047101.06129391
42Systemic lupus erythematosus_Homo sapiens_hsa053221.05421804
43Herpes simplex infection_Homo sapiens_hsa051681.05242035
44Oxidative phosphorylation_Homo sapiens_hsa001901.04266920
45Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.04030951
46HTLV-I infection_Homo sapiens_hsa051661.02665928
47Viral carcinogenesis_Homo sapiens_hsa052031.01598919
48Thyroid cancer_Homo sapiens_hsa052161.00767566
49Primary immunodeficiency_Homo sapiens_hsa053400.97956410
50Pyruvate metabolism_Homo sapiens_hsa006200.95645716
51Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.94786576
52Hepatitis B_Homo sapiens_hsa051610.90771587
53Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.89444041
54Purine metabolism_Homo sapiens_hsa002300.87605510
55Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.83068345
56Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82531831
57Alcoholism_Homo sapiens_hsa050340.82467412
582-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.82457957
59Basal cell carcinoma_Homo sapiens_hsa052170.81147153
60N-Glycan biosynthesis_Homo sapiens_hsa005100.81105245
61Measles_Homo sapiens_hsa051620.80883193
62TGF-beta signaling pathway_Homo sapiens_hsa043500.80415136
63Butanoate metabolism_Homo sapiens_hsa006500.79140402
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79109129
65Chronic myeloid leukemia_Homo sapiens_hsa052200.78813810
66Regulation of autophagy_Homo sapiens_hsa041400.78075589
67Wnt signaling pathway_Homo sapiens_hsa043100.76595656
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.73659390
69Pancreatic cancer_Homo sapiens_hsa052120.72860424
70Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.72684992
71Hippo signaling pathway_Homo sapiens_hsa043900.71559470
72Antigen processing and presentation_Homo sapiens_hsa046120.71251451
73Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.70980908
74Small cell lung cancer_Homo sapiens_hsa052220.70144708
75Shigellosis_Homo sapiens_hsa051310.69777699
76Viral myocarditis_Homo sapiens_hsa054160.66396123
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.66151999
78Phototransduction_Homo sapiens_hsa047440.64593407
79Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62052823
80Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.62033738
81Biosynthesis of amino acids_Homo sapiens_hsa012300.61834382
82T cell receptor signaling pathway_Homo sapiens_hsa046600.61493402
83B cell receptor signaling pathway_Homo sapiens_hsa046620.61284950
84Neurotrophin signaling pathway_Homo sapiens_hsa047220.61192015
85Protein export_Homo sapiens_hsa030600.61015968
86NF-kappa B signaling pathway_Homo sapiens_hsa040640.60803467
87Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60464991
88Non-small cell lung cancer_Homo sapiens_hsa052230.60127251
89Notch signaling pathway_Homo sapiens_hsa043300.59955172
90Pathways in cancer_Homo sapiens_hsa052000.59888565
91Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59762233
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.58818902
93Apoptosis_Homo sapiens_hsa042100.56450905
94Intestinal immune network for IgA production_Homo sapiens_hsa046720.54795130
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.54528531
96Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.53355119
97Endometrial cancer_Homo sapiens_hsa052130.53177306
98Hematopoietic cell lineage_Homo sapiens_hsa046400.53075405
99Alzheimers disease_Homo sapiens_hsa050100.52998890
100Hedgehog signaling pathway_Homo sapiens_hsa043400.52839352
101Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.51353711
102Leishmaniasis_Homo sapiens_hsa051400.50638727
103Melanoma_Homo sapiens_hsa052180.50485681
104Legionellosis_Homo sapiens_hsa051340.49003577
105RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.48744316
106Carbon metabolism_Homo sapiens_hsa012000.47751057
107Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.47237541
108Huntingtons disease_Homo sapiens_hsa050160.46103969
109Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.45851819
110Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.45748487
111Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.44731013
112Influenza A_Homo sapiens_hsa051640.43513253
113GABAergic synapse_Homo sapiens_hsa047270.42300506
114Acute myeloid leukemia_Homo sapiens_hsa052210.41436853
115MAPK signaling pathway_Homo sapiens_hsa040100.41399177
116Adherens junction_Homo sapiens_hsa045200.39478401
117Gap junction_Homo sapiens_hsa045400.39339479
118SNARE interactions in vesicular transport_Homo sapiens_hsa041300.38813382
119Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.38639900
120FoxO signaling pathway_Homo sapiens_hsa040680.38249999
121Prostate cancer_Homo sapiens_hsa052150.38218083
122PI3K-Akt signaling pathway_Homo sapiens_hsa041510.37465130
123Thyroid hormone signaling pathway_Homo sapiens_hsa049190.37108147
124Toxoplasmosis_Homo sapiens_hsa051450.36402740
125Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.35458551
126Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35334659
127Glioma_Homo sapiens_hsa052140.34608374
128Jak-STAT signaling pathway_Homo sapiens_hsa046300.34431454
129Toll-like receptor signaling pathway_Homo sapiens_hsa046200.33262451
130TNF signaling pathway_Homo sapiens_hsa046680.33116078
131Prolactin signaling pathway_Homo sapiens_hsa049170.32413853
132Metabolic pathways_Homo sapiens_hsa011000.32046708
133Asthma_Homo sapiens_hsa053100.29578453
134Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.29573195
135Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.28995094
136Taste transduction_Homo sapiens_hsa047420.28821969
137Olfactory transduction_Homo sapiens_hsa047400.28571888
138Axon guidance_Homo sapiens_hsa043600.27562034
139Dopaminergic synapse_Homo sapiens_hsa047280.25562842
140Cardiac muscle contraction_Homo sapiens_hsa042600.23834751
141Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22302527
142Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.18799220
143Peroxisome_Homo sapiens_hsa041460.17363848
144Dorso-ventral axis formation_Homo sapiens_hsa043200.17225607
145Glutathione metabolism_Homo sapiens_hsa004800.16088142
146Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.15783867
147Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.14037681
148Tight junction_Homo sapiens_hsa045300.13630385
149Fatty acid metabolism_Homo sapiens_hsa012120.12849593
150Morphine addiction_Homo sapiens_hsa050320.12168787
151Cocaine addiction_Homo sapiens_hsa050300.11886467
152Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.11668390

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »