RNF220

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle maturation (GO:0016188)4.64507510
2positive thymic T cell selection (GO:0045059)4.45297340
3mannose metabolic process (GO:0006013)4.27113387
4positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.23379525
5pre-miRNA processing (GO:0031054)4.16905122
6positive regulation of Rap GTPase activity (GO:0032854)3.88542182
7positive regulation of B cell differentiation (GO:0045579)3.82989191
8DNA unwinding involved in DNA replication (GO:0006268)3.80923460
9peptidyl-arginine omega-N-methylation (GO:0035247)3.74426529
10response to muramyl dipeptide (GO:0032495)3.69927220
11positive regulation of gamma-delta T cell activation (GO:0046645)3.68869464
12cellular hyperosmotic response (GO:0071474)3.62909607
13Peyers patch development (GO:0048541)3.62303578
14mucosal-associated lymphoid tissue development (GO:0048537)3.62303578
15locomotory exploration behavior (GO:0035641)3.50814485
16peptidyl-arginine N-methylation (GO:0035246)3.50319617
17peptidyl-arginine methylation (GO:0018216)3.50319617
18ribosomal small subunit biogenesis (GO:0042274)3.42339749
19negative regulation of histone methylation (GO:0031061)3.34492581
20definitive hemopoiesis (GO:0060216)3.33107114
21regulation of female receptivity (GO:0045924)3.30423137
22response to peptidoglycan (GO:0032494)3.30276899
23negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.28991729
24regulation of gamma-delta T cell differentiation (GO:0045586)3.26227882
25regulation of Rap GTPase activity (GO:0032317)3.25738369
26regulation of short-term neuronal synaptic plasticity (GO:0048172)3.25192578
27thymic T cell selection (GO:0045061)3.25120977
28cerebellar granule cell differentiation (GO:0021707)3.20803771
29L-amino acid import (GO:0043092)3.14960490
30negative regulation of histone acetylation (GO:0035067)3.14777521
313-UTR-mediated mRNA stabilization (GO:0070935)3.14692592
32histone arginine methylation (GO:0034969)3.14231227
33regulation of monocyte differentiation (GO:0045655)3.09612855
34protein-DNA complex disassembly (GO:0032986)3.09095089
35nucleosome disassembly (GO:0006337)3.09095089
36synaptic vesicle exocytosis (GO:0016079)2.99874841
37female mating behavior (GO:0060180)2.99769781
38positive T cell selection (GO:0043368)2.99764313
39peptidyl-arginine modification (GO:0018195)2.99345415
40positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.97819032
41regulation of leukocyte degranulation (GO:0043300)2.96733396
42positive regulation of synapse maturation (GO:0090129)2.96569422
43regulation of regulated secretory pathway (GO:1903305)2.96447143
44regulation of myeloid leukocyte mediated immunity (GO:0002886)2.95285933
45neuromuscular process controlling posture (GO:0050884)2.95089875
46regulation of translational termination (GO:0006449)2.93472818
47synaptic vesicle docking involved in exocytosis (GO:0016081)2.92834247
48negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.92651349
49negative regulation of microtubule polymerization (GO:0031115)2.91927716
50glutamate secretion (GO:0014047)2.89398508
51positive regulation of gene expression, epigenetic (GO:0045815)2.89068133
52negative regulation of erythrocyte differentiation (GO:0045647)2.88424462
53amino acid import (GO:0043090)2.87439349
54maturation of SSU-rRNA (GO:0030490)2.84565932
55layer formation in cerebral cortex (GO:0021819)2.83541194
56regulation of gamma-delta T cell activation (GO:0046643)2.81202223
57regulation of erythrocyte differentiation (GO:0045646)2.80665098
58ribosomal small subunit assembly (GO:0000028)2.79324182
59regulation of glutamate receptor signaling pathway (GO:1900449)2.77935242
60regulation of T-helper 2 cell differentiation (GO:0045628)2.76690933
61cell migration in hindbrain (GO:0021535)2.75828078
62dopamine receptor signaling pathway (GO:0007212)2.75377424
63peptidyl-lysine dimethylation (GO:0018027)2.75101498
64regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.74894281
65regulation of response to osmotic stress (GO:0047484)2.74322255
66negative thymic T cell selection (GO:0045060)2.73227480
67regulation of synaptic vesicle exocytosis (GO:2000300)2.72842259
68regulation of mammary gland epithelial cell proliferation (GO:0033599)2.72461412
69neuronal action potential propagation (GO:0019227)2.71864691
70dendritic spine morphogenesis (GO:0060997)2.71380909
71B cell receptor signaling pathway (GO:0050853)2.71266105
72regulation of neuronal synaptic plasticity (GO:0048168)2.71035028
73histone H4-K12 acetylation (GO:0043983)2.70805390
74regulation of long-term neuronal synaptic plasticity (GO:0048169)2.69933696
75negative regulation of histone modification (GO:0031057)2.69528876
76negative regulation of necrotic cell death (GO:0060547)2.66786534
77dosage compensation (GO:0007549)2.66242389
78modulation by virus of host process (GO:0019054)2.66169096
79regulation of B cell differentiation (GO:0045577)2.66094880
80positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.63980884
81antigen processing and presentation of endogenous antigen (GO:0019883)2.63762331
82negative regulation of gene expression, epigenetic (GO:0045814)2.63581028
83positive regulation of granulocyte differentiation (GO:0030854)2.63246884
84negative regulation of granulocyte differentiation (GO:0030853)2.61607395
85negative regulation of type 2 immune response (GO:0002829)2.60824341
86natural killer cell differentiation (GO:0001779)2.59162288
87G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.57974570
88creatine metabolic process (GO:0006600)2.57691282
89sodium ion export (GO:0071436)2.57260964
90establishment of mitochondrion localization (GO:0051654)2.57111474
91T cell selection (GO:0045058)2.57102456
92cellular protein complex disassembly (GO:0043624)2.56943634
93negative regulation of RNA splicing (GO:0033119)2.56359424
94peptidyl-tyrosine autophosphorylation (GO:0038083)2.55160610
95histone H4-K5 acetylation (GO:0043981)2.54601949
96histone H4-K8 acetylation (GO:0043982)2.54601949
97regulation of RNA export from nucleus (GO:0046831)2.53490301
98activation of JUN kinase activity (GO:0007257)2.52172754
99regulation of translational fidelity (GO:0006450)2.51688435
100protein complex localization (GO:0031503)2.51609037
101exploration behavior (GO:0035640)2.50830670
102regulation of granulocyte differentiation (GO:0030852)2.49892840
103viral transcription (GO:0019083)2.49651108
104regulation of mast cell degranulation (GO:0043304)2.48154524
105histone H2A acetylation (GO:0043968)2.47769706
106negative regulation of cell killing (GO:0031342)2.47219660
107negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.47219660
108viral life cycle (GO:0019058)2.46821287
109mitochondrion transport along microtubule (GO:0047497)2.45756452
110establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.45756452
111regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.45577274
112histone H3 deacetylation (GO:0070932)2.45382922
113membrane tubulation (GO:0097320)2.45016722
114regulation of ARF protein signal transduction (GO:0032012)2.44969166
115regulation of synaptic vesicle transport (GO:1902803)2.44491229
116central nervous system myelination (GO:0022010)2.43951032
117axon ensheathment in central nervous system (GO:0032291)2.43951032
118cellular response to thyroid hormone stimulus (GO:0097067)2.43820997
119phosphatidylglycerol biosynthetic process (GO:0006655)2.43644901
120negative regulation of chromatin modification (GO:1903309)2.42646926
121regulation of synaptic plasticity (GO:0048167)2.42640118
122pinocytosis (GO:0006907)2.42324330
123negative regulation of B cell apoptotic process (GO:0002903)2.42066537
124translational termination (GO:0006415)2.41673269
125negative regulation of circadian rhythm (GO:0042754)2.41120391
126negative regulation of peptidyl-lysine acetylation (GO:2000757)2.40701714
127positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.40454142
128cellular extravasation (GO:0045123)2.40287415
129regulation of nucleobase-containing compound transport (GO:0032239)2.38672059
130negative regulation of mRNA processing (GO:0050686)2.36657494
131histone H4 deacetylation (GO:0070933)2.36360470
132regulation of ARF GTPase activity (GO:0032312)2.34633871
133regulation of chromatin binding (GO:0035561)2.34460317
134regulation of helicase activity (GO:0051095)2.34205855
135nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.33466986
136regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.32801538
137mitotic G1 DNA damage checkpoint (GO:0031571)2.31791571
138DNA deamination (GO:0045006)2.30672372
139DNA damage response, signal transduction resulting in transcription (GO:0042772)2.30040641
140chromatin silencing (GO:0006342)2.29437342
141positive regulation of membrane potential (GO:0045838)2.27861667
142cerebellar Purkinje cell differentiation (GO:0021702)2.27376047
143intracellular estrogen receptor signaling pathway (GO:0030520)2.26866222
144histone H4-K16 acetylation (GO:0043984)2.26291595
145neurotransmitter secretion (GO:0007269)2.26224042
146regulation of synapse structural plasticity (GO:0051823)2.26097123
147positive regulation of cell cycle G2/M phase transition (GO:1902751)2.25727507
148positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.25727507
149nodal signaling pathway (GO:0038092)2.25709399
150megakaryocyte development (GO:0035855)2.25363793
151histone H2A monoubiquitination (GO:0035518)2.25099109
152translational elongation (GO:0006414)2.24367610
153protein complex disassembly (GO:0043241)2.23637226
154neuromuscular process controlling balance (GO:0050885)2.23446127
155protein localization to synapse (GO:0035418)2.22024448
156histone H4 acetylation (GO:0043967)2.21812572
157microtubule severing (GO:0051013)2.20307598
158DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.18851840
159regulation of histone H3-K9 methylation (GO:0051570)2.18068164
160DNA replication initiation (GO:0006270)2.15936865
161negative regulation of cytosolic calcium ion concentration (GO:0051481)2.15812335
162DNA strand elongation involved in DNA replication (GO:0006271)2.14661675
163DNA replication-dependent nucleosome assembly (GO:0006335)2.14622661
164DNA replication-dependent nucleosome organization (GO:0034723)2.14622661
165negative regulation of mRNA metabolic process (GO:1903312)2.14314863

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human4.28714581
2MYC_22102868_ChIP-Seq_BL_Human3.59782439
3EZH2_22144423_ChIP-Seq_EOC_Human3.00995767
4VDR_21846776_ChIP-Seq_THP-1_Human2.85051535
5THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.52681616
6* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.49195256
7KDM2B_26808549_Chip-Seq_DND41_Human2.39831842
8RARB_27405468_Chip-Seq_BRAIN_Mouse2.34594155
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.33448913
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.22318234
11EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.16730883
12KDM2B_26808549_Chip-Seq_SUP-B15_Human2.16413644
13* TCF7_22412390_ChIP-Seq_EML_Mouse2.14029947
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.13834352
15MYC_19079543_ChIP-ChIP_MESCs_Mouse2.05469176
16KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.03697010
17CIITA_25753668_ChIP-Seq_RAJI_Human2.00837910
18ZFP281_18757296_ChIP-ChIP_E14_Mouse1.99283325
19ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.92242125
20TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.90929330
21KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.90167069
22MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.89428436
23SCL_19346495_ChIP-Seq_HPC-7_Human1.88579268
24ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.76347996
25EGR1_19374776_ChIP-ChIP_THP-1_Human1.75604770
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.75513736
27VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.73969025
28CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.73716929
29ZFP281_27345836_Chip-Seq_ESCs_Mouse1.71639986
30SRY_22984422_ChIP-ChIP_TESTIS_Rat1.71484265
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.64185157
32SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.62806853
33CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.62073690
34STAT6_21828071_ChIP-Seq_BEAS2B_Human1.61410172
35KDM2B_26808549_Chip-Seq_JURKAT_Human1.59342804
36MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.59198457
37HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.54109074
38XRN2_22483619_ChIP-Seq_HELA_Human1.53793374
39E2F4_17652178_ChIP-ChIP_JURKAT_Human1.52121742
40UTX_26944678_Chip-Seq_JUKART_Human1.50515413
41* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.47662211
42MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.47642919
43DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.47629450
44* RACK7_27058665_Chip-Seq_MCF-7_Human1.46382909
45CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.45396284
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.44219345
47SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.43710461
48* P68_20966046_ChIP-Seq_HELA_Human1.43579011
49KDM2B_26808549_Chip-Seq_K562_Human1.41177670
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.41001049
51CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.38625904
52* BCOR_27268052_Chip-Seq_Bcells_Human1.38452766
53* LXR_22292898_ChIP-Seq_THP-1_Human1.37810878
54GATA1_19941827_ChIP-Seq_MEL_Mouse1.36377878
55PU.1_20513432_ChIP-Seq_Bcells_Mouse1.35901993
56E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.34847317
57CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.34804791
58EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.34732703
59TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.34660944
60TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.34451112
61* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.33373440
62* BCL6_27268052_Chip-Seq_Bcells_Human1.32727271
63IKZF1_21737484_ChIP-ChIP_HCT116_Human1.32727264
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.32419821
65VDR_24763502_ChIP-Seq_THP-1_Human1.32364328
66MYC_19030024_ChIP-ChIP_MESCs_Mouse1.31650779
67ELK3_25401928_ChIP-Seq_HUVEC_Human1.30532362
68MAF_26560356_Chip-Seq_TH1_Human1.29889359
69REST_18959480_ChIP-ChIP_MESCs_Mouse1.29823463
70MYC_18358816_ChIP-ChIP_MESCs_Mouse1.28430110
71* CTCF_27219007_Chip-Seq_Bcells_Human1.28042254
72FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.26736716
73TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.25437872
74KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25394939
75PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.24362276
76MAF_26560356_Chip-Seq_TH2_Human1.23845053
77SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.23329083
78IRF8_22096565_ChIP-ChIP_GC-B_Human1.22882911
79REST_21632747_ChIP-Seq_MESCs_Mouse1.22659281
80ZFX_18555785_ChIP-Seq_MESCs_Mouse1.22526455
81NCOR1_26117541_ChIP-Seq_K562_Human1.21895487
82DNAJC2_21179169_ChIP-ChIP_NT2_Human1.21888304
83WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.21497446
84GATA1_22383799_ChIP-Seq_G1ME_Mouse1.20907215
85BRD4_27068464_Chip-Seq_AML-cells_Mouse1.20504171
86CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.20014377
87* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.19264917
88MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.18890655
89GATA1_19941826_ChIP-Seq_K562_Human1.18288437
90* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.18239365
91GATA1_26923725_Chip-Seq_HPCs_Mouse1.18086667
92SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.17132450
93MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.16732276
94* PHF8_20622854_ChIP-Seq_HELA_Human1.16448622
95MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.15739460
96* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.15673063
97NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.15172413
98SETDB1_19884255_ChIP-Seq_MESCs_Mouse1.15036467
99* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.14256703
100GABP_19822575_ChIP-Seq_HepG2_Human1.13988982
101RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13846749
102* OCT4_19829295_ChIP-Seq_ESCs_Human1.13567678
103E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.13252933
104CTCF_26484167_Chip-Seq_Bcells_Mouse1.13189718
105SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.12987901
106NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.12288389
107DROSHA_22980978_ChIP-Seq_HELA_Human1.11051044
108SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.10782527
109RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.09657706
110SA1_27219007_Chip-Seq_ERYTHROID_Human1.08756782
111KDM5A_27292631_Chip-Seq_BREAST_Human1.08576677
112RUNX1_22412390_ChIP-Seq_EML_Mouse1.08530869
113* ELF1_20517297_ChIP-Seq_JURKAT_Human1.08321629
114* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.08167404
115MYCN_18555785_ChIP-Seq_MESCs_Mouse1.07023431
116POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.06715340
117* SA1_27219007_Chip-Seq_Bcells_Human1.06136780
118* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.06059529
119ETS1_21867929_ChIP-Seq_TH2_Mouse1.04287601
120RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03194950
121ZNF263_19887448_ChIP-Seq_K562_Human1.03116464
122SMC4_20622854_ChIP-Seq_HELA_Human1.02405715
123TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.00063285
124SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.99831188
125RARG_19884340_ChIP-ChIP_MEFs_Mouse0.99285294
126TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.98394056
127NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.98347673
128* FOXP1_21924763_ChIP-Seq_HESCs_Human0.98303752
129KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.98177953
130PKCTHETA_26484144_Chip-Seq_BREAST_Human0.98091396
131* E2F1_20622854_ChIP-Seq_HELA_Human0.96926833
132GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.96904614
133* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.96904233
134GATA2_22383799_ChIP-Seq_G1ME_Mouse0.96815122
135TET1_21451524_ChIP-Seq_MESCs_Mouse0.96495739
136SPI1_23127762_ChIP-Seq_K562_Human0.95609697
137CTCF_21964334_ChIP-Seq_BJAB-B_Human0.95349777
138TTF2_22483619_ChIP-Seq_HELA_Human0.93234209
139TP53_22127205_ChIP-Seq_IMR90_Human0.93219986
140E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.92703652
141CTCF_27219007_Chip-Seq_ERYTHROID_Human0.92668187
142ETS1_20019798_ChIP-Seq_JURKAT_Human0.92180174
143* CREB1_26743006_Chip-Seq_LNCaP_Human0.91828416
144E2F1_21310950_ChIP-Seq_MCF-7_Human0.91633063

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.12386356
2MP0003635_abnormal_synaptic_transmissio2.75389090
3MP0003436_decreased_susceptibility_to2.75094768
4MP0004270_analgesia2.73690063
5MP0003303_peritoneal_inflammation2.70963033
6MP0003693_abnormal_embryo_hatching2.49879113
7MP0002653_abnormal_ependyma_morphology2.49786529
8MP0008877_abnormal_DNA_methylation2.37867926
9MP0003880_abnormal_central_pattern2.35107676
10MP0005058_abnormal_lysosome_morphology2.14752813
11MP0010094_abnormal_chromosome_stability2.05965425
12MP0002063_abnormal_learning/memory/cond2.01955844
13MP0009379_abnormal_foot_pigmentation1.99692105
14MP0002064_seizures1.93748108
15MP0003077_abnormal_cell_cycle1.91525944
16MP0003111_abnormal_nucleus_morphology1.91071765
17MP0003690_abnormal_glial_cell1.90781313
18MP0003123_paternal_imprinting1.88811407
19MP0008260_abnormal_autophagy1.87502650
20MP0002396_abnormal_hematopoietic_system1.87045280
21MP0004957_abnormal_blastocyst_morpholog1.83380331
22MP0001486_abnormal_startle_reflex1.82033450
23MP0009745_abnormal_behavioral_response1.74165881
24MP0005464_abnormal_platelet_physiology1.73500812
25MP0005423_abnormal_somatic_nervous1.73174786
26MP0002272_abnormal_nervous_system1.67851858
27MP0005174_abnormal_tail_pigmentation1.65259848
28MP0004811_abnormal_neuron_physiology1.62686504
29MP0009046_muscle_twitch1.60604352
30MP0001730_embryonic_growth_arrest1.57726261
31MP0008057_abnormal_DNA_replication1.56199312
32MP0005451_abnormal_body_composition1.53613022
33MP0004133_heterotaxia1.51275249
34MP0004885_abnormal_endolymph1.50558128
35MP0002572_abnormal_emotion/affect_behav1.47141051
36MP0005025_abnormal_response_to1.46778941
37MP0000604_amyloidosis1.46711574
38MP0001501_abnormal_sleep_pattern1.42833450
39MP0000955_abnormal_spinal_cord1.42102756
40MP0003075_altered_response_to1.40900367
41MP0001968_abnormal_touch/_nociception1.38585520
42MP0003787_abnormal_imprinting1.37604497
43MP0008961_abnormal_basal_metabolism1.37221671
44MP0002419_abnormal_innate_immunity1.36941819
45MP0004808_abnormal_hematopoietic_stem1.34881577
46MP0008569_lethality_at_weaning1.34518323
47MP0003121_genomic_imprinting1.34125469
48MP0002420_abnormal_adaptive_immunity1.33394190
49MP0001835_abnormal_antigen_presentation1.32584436
50MP0005000_abnormal_immune_tolerance1.32275744
51MP0005076_abnormal_cell_differentiation1.31955076
52MP0002249_abnormal_larynx_morphology1.30300102
53MP0001819_abnormal_immune_cell1.30277010
54MP0002084_abnormal_developmental_patter1.29873927
55MP0001529_abnormal_vocalization1.29537307
56MP0000350_abnormal_cell_proliferation1.26972752
57MP0002132_abnormal_respiratory_system1.26679035
58MP0003183_abnormal_peptide_metabolism1.25898312
59MP0002734_abnormal_mechanical_nocicepti1.25867154
60MP0004185_abnormal_adipocyte_glucose1.24682176
61MP0003122_maternal_imprinting1.22696769
62MP0003861_abnormal_nervous_system1.21815432
63MP0000716_abnormal_immune_system1.21691654
64MP0009278_abnormal_bone_marrow1.20860420
65MP0005410_abnormal_fertilization1.18508451
66MP0002822_catalepsy1.17873617
67MP0002152_abnormal_brain_morphology1.17784728
68MP0002085_abnormal_embryonic_tissue1.17628637
69MP0000685_abnormal_immune_system1.17399494
70MP0006292_abnormal_olfactory_placode1.15912226
71MP0002882_abnormal_neuron_morphology1.14678693
72MP0001800_abnormal_humoral_immune1.14179744
73MP0002723_abnormal_immune_serum1.12838007
74MP0005394_taste/olfaction_phenotype1.12729125
75MP0005499_abnormal_olfactory_system1.12729125
76MP0001929_abnormal_gametogenesis1.11327278
77MP0002429_abnormal_blood_cell1.11241053
78MP0000681_abnormal_thyroid_gland1.10849169
79MP0003879_abnormal_hair_cell1.10038355
80MP0002722_abnormal_immune_system1.09387879
81MP0004145_abnormal_muscle_electrophysio1.08558682
82MP0008007_abnormal_cellular_replicative1.07414541
83MP0009672_abnormal_birth_weight1.07016627
84MP0004742_abnormal_vestibular_system1.07003287
85MP0000703_abnormal_thymus_morphology1.06956766
86MP0003329_amyloid_beta_deposits1.05976499
87MP0003191_abnormal_cellular_cholesterol1.05315902
88MP0001970_abnormal_pain_threshold1.04840950
89MP0003634_abnormal_glial_cell1.04422563
90MP0000778_abnormal_nervous_system1.04230564
91MP0000689_abnormal_spleen_morphology1.02816111
92MP0002210_abnormal_sex_determination1.01186795
93MP0002398_abnormal_bone_marrow1.01117891
94MP0002557_abnormal_social/conspecific_i1.00739072
95MP0008770_decreased_survivor_rate1.00717400
96MP0003763_abnormal_thymus_physiology1.00308953
97MP0004142_abnormal_muscle_tone0.99920272
98MP0005397_hematopoietic_system_phenotyp0.99607975
99MP0001545_abnormal_hematopoietic_system0.99607975
100MP0001851_eye_inflammation0.99128700
101MP0002909_abnormal_adrenal_gland0.98964809
102MP0002066_abnormal_motor_capabilities/c0.98598779
103MP0004924_abnormal_behavior0.98597044
104MP0005386_behavior/neurological_phenoty0.98597044
105MP0001790_abnormal_immune_system0.98193638
106MP0005387_immune_system_phenotype0.98193638
107MP0002405_respiratory_system_inflammati0.98151559
108MP0002452_abnormal_antigen_presenting0.97222497
109MP0001849_ear_inflammation0.97058307
110MP0003698_abnormal_male_reproductive0.94947053
111MP0001697_abnormal_embryo_size0.94365088
112MP0003866_abnormal_defecation0.94109880
113MP0005666_abnormal_adipose_tissue0.93418974
114MP0008058_abnormal_DNA_repair0.93336756
115MP0001485_abnormal_pinna_reflex0.93222161
116MP0001905_abnormal_dopamine_level0.92948399
117MP0002080_prenatal_lethality0.92800089
118MP0002733_abnormal_thermal_nociception0.92748361
119MP0000537_abnormal_urethra_morphology0.91003897
120MP0009840_abnormal_foam_cell0.90288497
121MP0003633_abnormal_nervous_system0.90024491
122MP0009333_abnormal_splenocyte_physiolog0.89732627
123MP0001145_abnormal_male_reproductive0.89591800
124MP0001502_abnormal_circadian_rhythm0.89180448
125MP0000490_abnormal_crypts_of0.88440452
126MP0001440_abnormal_grooming_behavior0.88033623
127MP0001853_heart_inflammation0.87601709
128MP0002067_abnormal_sensory_capabilities0.87296943
129MP0000313_abnormal_cell_death0.87285202
130MP0004233_abnormal_muscle_weight0.85477405
131MP0004130_abnormal_muscle_cell0.84615767
132MP0000653_abnormal_sex_gland0.84506742
133MP0002184_abnormal_innervation0.84194115
134MP0000631_abnormal_neuroendocrine_gland0.83915982
135MP0005535_abnormal_body_temperature0.83507643
136MP0004947_skin_inflammation0.83338997
137MP0003646_muscle_fatigue0.82912627
138MP0000920_abnormal_myelination0.82370462
139MP0002089_abnormal_postnatal_growth/wei0.81675804
140MP0002735_abnormal_chemical_nociception0.80748823
141MP0003631_nervous_system_phenotype0.80671689
142MP0005075_abnormal_melanosome_morpholog0.80062898
143MP0003656_abnormal_erythrocyte_physiolo0.79689817
144MP0004858_abnormal_nervous_system0.79686306
145MP0003172_abnormal_lysosome_physiology0.79495262
146MP0002161_abnormal_fertility/fecundity0.79300281
147MP0001672_abnormal_embryogenesis/_devel0.78871944
148MP0005380_embryogenesis_phenotype0.78871944
149MP0002736_abnormal_nociception_after0.78013023
150MP0008872_abnormal_physiological_respon0.77964443
151MP0002019_abnormal_tumor_incidence0.77098330
152MP0005409_darkened_coat_color0.76993409
153MP0008874_decreased_physiological_sensi0.76009929
154MP0001533_abnormal_skeleton_physiology0.75392432
155MP0002102_abnormal_ear_morphology0.75348520
156MP0000747_muscle_weakness0.74337046
157MP0001348_abnormal_lacrimal_gland0.73946533
158MP0001873_stomach_inflammation0.73118450
159MP0000678_abnormal_parathyroid_gland0.72847100
160MP0001986_abnormal_taste_sensitivity0.72076479

Predicted human phenotypes

RankGene SetZ-score
1Hyperacusis (HP:0010780)4.68779622
2Myokymia (HP:0002411)3.92140026
3Insomnia (HP:0100785)3.55718440
4Cellulitis (HP:0100658)3.31895593
5Visual hallucinations (HP:0002367)3.30651723
6Abnormality of binocular vision (HP:0011514)3.28672575
7Diplopia (HP:0000651)3.28672575
8Overriding aorta (HP:0002623)3.20897476
9Annular pancreas (HP:0001734)3.14246082
10Neurofibrillary tangles (HP:0002185)3.05850803
11Obstructive sleep apnea (HP:0002870)3.05582990
12Pointed chin (HP:0000307)2.88243754
13Obstructive lung disease (HP:0006536)2.87954625
14Chronic obstructive pulmonary disease (HP:0006510)2.87954625
15Papilledema (HP:0001085)2.85972325
16Ankle clonus (HP:0011448)2.81994712
17Centrally nucleated skeletal muscle fibers (HP:0003687)2.81643091
18Agammaglobulinemia (HP:0004432)2.79797046
19Focal seizures (HP:0007359)2.77928925
20Urinary urgency (HP:0000012)2.76519065
21Cerebral hypomyelination (HP:0006808)2.75390529
22Elfin facies (HP:0004428)2.70976872
23Focal motor seizures (HP:0011153)2.70152504
24Cerebral inclusion bodies (HP:0100314)2.69784588
25Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.63870567
26Acute lymphatic leukemia (HP:0006721)2.63659480
27Spastic gait (HP:0002064)2.63085973
28Progressive inability to walk (HP:0002505)2.61900976
29Asplenia (HP:0001746)2.61819171
30Segmental peripheral demyelination/remyelination (HP:0003481)2.56223172
31Polygenic inheritance (HP:0010982)2.56022824
32Increased cerebral lipofuscin (HP:0011813)2.55424743
33Eczematoid dermatitis (HP:0000976)2.55220586
34Supranuclear gaze palsy (HP:0000605)2.54091576
35Elevated erythrocyte sedimentation rate (HP:0003565)2.54086398
36Increased neuronal autofluorescent lipopigment (HP:0002074)2.51809981
37Peripheral hypomyelination (HP:0007182)2.49282156
38Renal duplication (HP:0000075)2.49232854
39Truncus arteriosus (HP:0001660)2.47662362
40Flat cornea (HP:0007720)2.45811470
41Aplasia/Hypoplasia of the spleen (HP:0010451)2.43972439
42Mediastinal lymphadenopathy (HP:0100721)2.42153591
43Thoracic kyphosis (HP:0002942)2.38571551
44Urinary bladder sphincter dysfunction (HP:0002839)2.38525507
45Ragged-red muscle fibers (HP:0003200)2.38129442
46Abnormality of the lower motor neuron (HP:0002366)2.34297731
47Bowel incontinence (HP:0002607)2.32305217
48Increased nuchal translucency (HP:0010880)2.32131522
49Impaired vibration sensation in the lower limbs (HP:0002166)2.31297223
50Ependymoma (HP:0002888)2.28419685
51Poor eye contact (HP:0000817)2.27969374
52Abnormality of cells of the erythroid lineage (HP:0012130)2.27955651
53Renovascular hypertension (HP:0100817)2.27895869
54Basal cell carcinoma (HP:0002671)2.27392284
55Gastrointestinal inflammation (HP:0004386)2.26333367
56Hyperthyroidism (HP:0000836)2.26048080
57Slow saccadic eye movements (HP:0000514)2.24973921
58Hypertensive crisis (HP:0100735)2.24783594
59Megalocornea (HP:0000485)2.24709771
60Prolonged bleeding time (HP:0003010)2.23659513
61Recurrent fungal infections (HP:0002841)2.23573547
62Depression (HP:0000716)2.23412346
63Meningitis (HP:0001287)2.21456830
64Colitis (HP:0002583)2.20346885
65Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.19726817
66Panhypogammaglobulinemia (HP:0003139)2.19523402
67Neoplasm of the oral cavity (HP:0100649)2.18428350
68Exercise-induced myalgia (HP:0003738)2.17932206
69Abnormal large intestine physiology (HP:0012700)2.15135961
70Foot dorsiflexor weakness (HP:0009027)2.14136125
71Abnormality of the diencephalon (HP:0010662)2.13801090
72Abnormality of the labia minora (HP:0012880)2.12581746
73Seborrheic dermatitis (HP:0001051)2.11965473
74Pallor (HP:0000980)2.09863087
75Sacral dimple (HP:0000960)2.09590136
76Increased IgE level (HP:0003212)2.09563365
77Dysmetric saccades (HP:0000641)2.07085086
78Microvesicular hepatic steatosis (HP:0001414)2.06963802
79Diminished motivation (HP:0000745)2.06879661
80Broad-based gait (HP:0002136)2.05979246
81Progressive muscle weakness (HP:0003323)2.05469205
82Premature skin wrinkling (HP:0100678)2.04999343
83Mutism (HP:0002300)2.04670549
84Abnormality of the corticospinal tract (HP:0002492)2.03816435
85Abnormality of saccadic eye movements (HP:0000570)2.03121837
86Onion bulb formation (HP:0003383)2.03102077
87Apathy (HP:0000741)2.03031010
88Abnormality of the thoracic spine (HP:0100711)2.02013359
89Deep palmar crease (HP:0006191)2.01797244
90Myositis (HP:0100614)2.00455842
91Medulloblastoma (HP:0002885)2.00364174
92Abnormal number of erythroid precursors (HP:0012131)1.99896304
93Impaired smooth pursuit (HP:0007772)1.99513911
94Muscle stiffness (HP:0003552)1.99365885
95Supernumerary spleens (HP:0009799)1.99362725
96Postural instability (HP:0002172)1.98757123
97Lower limb asymmetry (HP:0100559)1.98677337
98Amyotrophic lateral sclerosis (HP:0007354)1.98061097
99Recurrent abscess formation (HP:0002722)1.98058321
100Epileptic encephalopathy (HP:0200134)1.98030916
101Abnormal social behavior (HP:0012433)1.95617275
102Impaired social interactions (HP:0000735)1.95617275
103Chronic mucocutaneous candidiasis (HP:0002728)1.94857022
104Recurrent cutaneous fungal infections (HP:0011370)1.94857022
105Esophageal atresia (HP:0002032)1.94855533
106Nonprogressive disorder (HP:0003680)1.94712771
107Nasal polyposis (HP:0100582)1.94114171
108Abnormality of the foot musculature (HP:0001436)1.92743115
109Termporal pattern (HP:0011008)1.92725902
110Insidious onset (HP:0003587)1.92725902
111Dysmetria (HP:0001310)1.92243053
112Atonic seizures (HP:0010819)1.91030767
113Tented upper lip vermilion (HP:0010804)1.90032792
114CNS hypomyelination (HP:0003429)1.89944682
115Achilles tendon contracture (HP:0001771)1.89931546
116Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.89244626
117Degeneration of the lateral corticospinal tracts (HP:0002314)1.89244626
118Intention tremor (HP:0002080)1.89057003
119Recurrent bacterial skin infections (HP:0005406)1.88514528
120Abnormality of the fingertips (HP:0001211)1.87694596
121Facial hemangioma (HP:0000329)1.87643505
122Tetraplegia (HP:0002445)1.87108509
123Abnormality of ocular smooth pursuit (HP:0000617)1.86432340
124Reticulocytopenia (HP:0001896)1.86108471
125Febrile seizures (HP:0002373)1.85801329
126Myopathic facies (HP:0002058)1.85718395
127Truncal ataxia (HP:0002078)1.84419053
128Recurrent viral infections (HP:0004429)1.83932063
129Dysostosis multiplex (HP:0000943)1.83896030
130Aplastic anemia (HP:0001915)1.83888000
131Rigidity (HP:0002063)1.82837005
132Dysphonia (HP:0001618)1.82590863
133Abnormality of the musculature of the hand (HP:0001421)1.82091061
134Abnormality of the nasal mucosa (HP:0000433)1.81717768
135Stereotypic behavior (HP:0000733)1.81597016
136Generalized hypotonia (HP:0001290)1.79785718
137Athetosis (HP:0002305)1.78627909
138Obsessive-compulsive behavior (HP:0000722)1.77911601
139Abnormality of the periventricular white matter (HP:0002518)1.77471398
140Epistaxis (HP:0000421)1.77411194
141Rib fusion (HP:0000902)1.75029344
142Attention deficit hyperactivity disorder (HP:0007018)1.74886456
143Genetic anticipation (HP:0003743)1.74089601
144Inappropriate behavior (HP:0000719)1.73288439
145Gaze-evoked nystagmus (HP:0000640)1.70724285
146Abnormality of the astrocytes (HP:0100707)1.70606430
147Astrocytoma (HP:0009592)1.70606430
148Prominent nose (HP:0000448)1.69536344
149Chronic otitis media (HP:0000389)1.66826878
150Hemiplegia (HP:0002301)1.65090683
151Abnormality of the carotid arteries (HP:0005344)1.63364624
152Colon cancer (HP:0003003)1.61176727
153Male infertility (HP:0003251)1.60697575
154Thrombocytosis (HP:0001894)1.60506072
155Bradykinesia (HP:0002067)1.59622566
156Clonus (HP:0002169)1.58346016
157Neuronal loss in central nervous system (HP:0002529)1.58302624
158Macroorchidism (HP:0000053)1.58084122
159High anterior hairline (HP:0009890)1.57923522
160Neoplasm of striated muscle (HP:0009728)1.55710041
161Heterotopia (HP:0002282)1.54470143
162Acute myeloid leukemia (HP:0004808)1.51499901
163Action tremor (HP:0002345)1.51488329
164Abnormality of chromosome segregation (HP:0002916)1.50965174
165Rapidly progressive (HP:0003678)1.49263831
166Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.49139836
167Neoplasm of the heart (HP:0100544)1.47497046

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EEF2K4.02428512
2PRPF4B3.75665705
3CDK193.27317151
4ERN13.12588438
5MAP3K93.04695345
6TYRO32.63595969
7RIPK42.51517612
8SMG12.45649874
9PRKD32.43453681
10ICK2.32601272
11KSR22.22380000
12MAP3K112.15860953
13NTRK21.90212449
14MAP3K41.79718230
15TAOK11.79299139
16CDC71.75465845
17UHMK11.71215309
18SCYL21.70928041
19PAK61.65675869
20DAPK11.56576265
21MAP3K61.51453542
22ALK1.50966024
23MAP2K31.46983231
24HIPK21.43039487
25MINK11.41110111
26PKN21.39312814
27MAP3K11.37757390
28MAP3K101.37715926
29MAPKAPK51.37455474
30KSR11.35771866
31MAPKAPK31.34148546
32NTRK31.29501795
33RAF11.23588026
34EPHA41.23548691
35NME21.22001530
36RIPK11.21149781
37CAMKK11.21008838
38MUSK1.20208727
39CDK121.17702059
40MAP3K121.15536091
41MAP4K11.13580839
42MAPK121.12988400
43SIK11.11586023
44PNCK1.10939861
45TRIB31.09669644
46TBK11.09161505
47MARK21.08976716
48RET1.07654098
49KIT1.05681189
50LRRK21.03904929
51PASK1.03890630
52BCKDK1.02801380
53NEK21.01153691
54FES1.00185125
55BRSK10.99341530
56IRAK30.98038780
57PDPK10.97345737
58TAOK30.95391291
59IRAK20.95242360
60MAP2K20.94400113
61MAP2K70.93194253
62TAOK20.93152758
63BUB10.92641647
64WEE10.91447176
65SIK20.91029025
66PRKD20.87068212
67MARK10.86438591
68MAP2K40.86244131
69MAPK150.85543928
70STK380.85344230
71MAP3K130.84921851
72VRK10.83070376
73CDK11A0.81945820
74TIE10.81683671
75MAP3K70.77860409
76CLK10.77787295
77CDK150.77732124
78CDK180.77526752
79CDK50.77223359
80SYK0.76124672
81FGFR20.75605342
82GRK60.75550193
83CAMK10.75253814
84PRKG20.74948615
85RPS6KL10.74080449
86RPS6KC10.74080449
87TESK20.73893193
88BRD40.71901614
89JAK30.70441708
90DAPK20.70400412
91TTK0.70161102
92CSNK1G30.70152867
93BTK0.70078347
94MAPK110.69317667
95TGFBR10.69235250
96CDK140.68490535
97CDK40.67981003
98RPS6KB20.66701172
99PRKCH0.65242961
100CSNK1G20.65136274
101FLT30.64484043
102VRK20.63300373
103TNK20.62883579
104ZAP700.62107089
105PDK10.61445760
106MAP3K80.61297771
107RPS6KA20.60999587
108MAPK100.60544338
109MAPK130.59542860
110BMX0.59100888
111STK110.58481702
112RPS6KA60.58460779
113LATS20.58035427
114CHEK20.57548083
115CHEK10.57083269
116CDK70.56812161
117IRAK40.55592352
118MAP2K60.55451849
119ARAF0.54362662
120CAMK40.54157719
121ATR0.53763261
122CDK20.53486298
123MAPK40.53449249
124CAMK1D0.52713829
125CSF1R0.52652937
126HCK0.52282921
127AKT20.51300307
128NTRK10.50862427
129CDC42BPA0.49633554
130CDK90.49341274
131STK100.48873406
132ITK0.46466236
133DYRK1A0.45627935
134FGFR40.45061073
135MAP3K20.44179659
136MAPK30.44088198
137RPS6KA10.43820781
138CSNK1E0.43692925
139MTOR0.43508183
140JAK20.42732252
141DYRK30.42111398
142CSNK1A1L0.42063715
143WNK10.42027537
144MATK0.40913268
145TNIK0.40901182
146LIMK10.40577705
147MAPK80.40461252
148DYRK1B0.37579080
149DAPK30.36607699
150LCK0.36399110
151TYK20.36398950

Predicted pathways (KEGG)

RankGene SetZ-score
1Other glycan degradation_Homo sapiens_hsa005112.54220027
2Olfactory transduction_Homo sapiens_hsa047402.27268855
3DNA replication_Homo sapiens_hsa030302.03166662
4Mismatch repair_Homo sapiens_hsa034301.88377246
5Long-term potentiation_Homo sapiens_hsa047201.82696777
6Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.74952089
7Synaptic vesicle cycle_Homo sapiens_hsa047211.65348924
8Oocyte meiosis_Homo sapiens_hsa041141.62038257
9Leishmaniasis_Homo sapiens_hsa051401.61805097
10mRNA surveillance pathway_Homo sapiens_hsa030151.54462375
11Spliceosome_Homo sapiens_hsa030401.53205237
12Circadian entrainment_Homo sapiens_hsa047131.51952249
13Colorectal cancer_Homo sapiens_hsa052101.48838570
14Base excision repair_Homo sapiens_hsa034101.47223062
15Cell cycle_Homo sapiens_hsa041101.45601321
16Dopaminergic synapse_Homo sapiens_hsa047281.45385078
17Glutamatergic synapse_Homo sapiens_hsa047241.44393674
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.44282161
19Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.40328196
20Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.39058162
21Long-term depression_Homo sapiens_hsa047301.37742265
22Notch signaling pathway_Homo sapiens_hsa043301.33154124
23RNA transport_Homo sapiens_hsa030131.32957010
24VEGF signaling pathway_Homo sapiens_hsa043701.29825685
25Osteoclast differentiation_Homo sapiens_hsa043801.29503740
26Amphetamine addiction_Homo sapiens_hsa050311.29285129
27GnRH signaling pathway_Homo sapiens_hsa049121.28724604
28Non-small cell lung cancer_Homo sapiens_hsa052231.27704108
29Aldosterone synthesis and secretion_Homo sapiens_hsa049251.26784093
30Morphine addiction_Homo sapiens_hsa050321.25011931
31Salivary secretion_Homo sapiens_hsa049701.21668085
32Neurotrophin signaling pathway_Homo sapiens_hsa047221.21325812
33Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.19565468
34Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.18815817
35Gastric acid secretion_Homo sapiens_hsa049711.18559951
36Cholinergic synapse_Homo sapiens_hsa047251.17875687
37Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.17666731
38Gap junction_Homo sapiens_hsa045401.16519503
39Carbohydrate digestion and absorption_Homo sapiens_hsa049731.16190924
40GABAergic synapse_Homo sapiens_hsa047271.14909541
41Nicotine addiction_Homo sapiens_hsa050331.14198480
42Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.13241054
43Cocaine addiction_Homo sapiens_hsa050301.12780911
44ErbB signaling pathway_Homo sapiens_hsa040121.11465431
45Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.10046074
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.09484551
47Pentose phosphate pathway_Homo sapiens_hsa000301.07727021
48Glioma_Homo sapiens_hsa052141.07726970
49Oxytocin signaling pathway_Homo sapiens_hsa049211.05526421
50Chronic myeloid leukemia_Homo sapiens_hsa052201.04933838
51B cell receptor signaling pathway_Homo sapiens_hsa046621.04742067
52RNA degradation_Homo sapiens_hsa030181.04319115
53Estrogen signaling pathway_Homo sapiens_hsa049151.04318583
54Ribosome_Homo sapiens_hsa030101.03576555
55Thyroid hormone signaling pathway_Homo sapiens_hsa049191.00043888
56Alcoholism_Homo sapiens_hsa050340.99792442
57mTOR signaling pathway_Homo sapiens_hsa041500.97789939
58Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.97189266
59Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.96074449
60Phospholipase D signaling pathway_Homo sapiens_hsa040720.95924683
61Toll-like receptor signaling pathway_Homo sapiens_hsa046200.93821494
62Dorso-ventral axis formation_Homo sapiens_hsa043200.92481642
63Wnt signaling pathway_Homo sapiens_hsa043100.92188568
64Phosphatidylinositol signaling system_Homo sapiens_hsa040700.91229803
65Basal transcription factors_Homo sapiens_hsa030220.89785726
66Axon guidance_Homo sapiens_hsa043600.88434254
67Homologous recombination_Homo sapiens_hsa034400.88321579
68Insulin secretion_Homo sapiens_hsa049110.87454487
69Tuberculosis_Homo sapiens_hsa051520.87426312
70Prion diseases_Homo sapiens_hsa050200.87253995
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.87011462
72Asthma_Homo sapiens_hsa053100.84624657
73Choline metabolism in cancer_Homo sapiens_hsa052310.83730941
74Pancreatic cancer_Homo sapiens_hsa052120.83064449
75Serotonergic synapse_Homo sapiens_hsa047260.82814097
76Endocytosis_Homo sapiens_hsa041440.82624210
77Melanogenesis_Homo sapiens_hsa049160.82599298
78Sphingolipid signaling pathway_Homo sapiens_hsa040710.82393491
79cAMP signaling pathway_Homo sapiens_hsa040240.82244912
80Thyroid cancer_Homo sapiens_hsa052160.81339373
81Glycerophospholipid metabolism_Homo sapiens_hsa005640.81265456
82MAPK signaling pathway_Homo sapiens_hsa040100.80534521
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.80265549
84Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.80184113
85Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.79077827
86Calcium signaling pathway_Homo sapiens_hsa040200.78231081
87Renal cell carcinoma_Homo sapiens_hsa052110.77636834
88SNARE interactions in vesicular transport_Homo sapiens_hsa041300.77319782
89Platelet activation_Homo sapiens_hsa046110.76564590
90Herpes simplex infection_Homo sapiens_hsa051680.76016311
91Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.75531268
92Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.74990418
93T cell receptor signaling pathway_Homo sapiens_hsa046600.74698624
94RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.73901737
95Acute myeloid leukemia_Homo sapiens_hsa052210.73427941
96Allograft rejection_Homo sapiens_hsa053300.71429920
97Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70219369
98Hepatitis B_Homo sapiens_hsa051610.69936709
99Renin secretion_Homo sapiens_hsa049240.69648863
100Endometrial cancer_Homo sapiens_hsa052130.69117345
101Shigellosis_Homo sapiens_hsa051310.69052173
102Toxoplasmosis_Homo sapiens_hsa051450.66120547
103Insulin signaling pathway_Homo sapiens_hsa049100.65945790
104Influenza A_Homo sapiens_hsa051640.65858946
105Type II diabetes mellitus_Homo sapiens_hsa049300.64552283
106Sulfur relay system_Homo sapiens_hsa041220.64012512
107Fanconi anemia pathway_Homo sapiens_hsa034600.63920188
108Hippo signaling pathway_Homo sapiens_hsa043900.63051854
109cGMP-PKG signaling pathway_Homo sapiens_hsa040220.62946164
110Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.62249362
111Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.62059366
112Primary immunodeficiency_Homo sapiens_hsa053400.61922950
113Ras signaling pathway_Homo sapiens_hsa040140.61318531
114Nucleotide excision repair_Homo sapiens_hsa034200.59884050
115HTLV-I infection_Homo sapiens_hsa051660.59874866
116MicroRNAs in cancer_Homo sapiens_hsa052060.59353817
117Intestinal immune network for IgA production_Homo sapiens_hsa046720.58381224
118Inositol phosphate metabolism_Homo sapiens_hsa005620.57335519
119Autoimmune thyroid disease_Homo sapiens_hsa053200.57290032
120Central carbon metabolism in cancer_Homo sapiens_hsa052300.57062024
121Epstein-Barr virus infection_Homo sapiens_hsa051690.55827536
122Non-homologous end-joining_Homo sapiens_hsa034500.55770046
123Chemokine signaling pathway_Homo sapiens_hsa040620.54430283
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54025937
125Basal cell carcinoma_Homo sapiens_hsa052170.53731730
126Apoptosis_Homo sapiens_hsa042100.53437193
127Rap1 signaling pathway_Homo sapiens_hsa040150.52831498
128Hedgehog signaling pathway_Homo sapiens_hsa043400.52655481
129Hepatitis C_Homo sapiens_hsa051600.52190992
130Glycosaminoglycan degradation_Homo sapiens_hsa005310.51853063
131Adipocytokine signaling pathway_Homo sapiens_hsa049200.51809975
132Pathways in cancer_Homo sapiens_hsa052000.51514622
133Type I diabetes mellitus_Homo sapiens_hsa049400.50772851
134Bladder cancer_Homo sapiens_hsa052190.50689292
135Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50294552

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