

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 7.65654201 |
| 2 | sequestering of actin monomers (GO:0042989) | 7.52045858 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 6.91491612 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.91491612 |
| 5 | viral transcription (GO:0019083) | 5.73470772 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.63569064 |
| 7 | translational termination (GO:0006415) | 5.56296692 |
| 8 | regulation of glucokinase activity (GO:0033131) | 5.52042196 |
| 9 | regulation of hexokinase activity (GO:1903299) | 5.52042196 |
| 10 | respiratory electron transport chain (GO:0022904) | 5.42306446 |
| 11 | protein neddylation (GO:0045116) | 5.32093278 |
| 12 | electron transport chain (GO:0022900) | 5.30413944 |
| 13 | positive regulation of gastrulation (GO:2000543) | 5.16407711 |
| 14 | cytidine metabolic process (GO:0046087) | 4.85960992 |
| 15 | cytidine catabolic process (GO:0006216) | 4.85960992 |
| 16 | cytidine deamination (GO:0009972) | 4.85960992 |
| 17 | ribosomal small subunit assembly (GO:0000028) | 4.77053086 |
| 18 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.75378669 |
| 19 | cotranslational protein targeting to membrane (GO:0006613) | 4.71919268 |
| 20 | translational elongation (GO:0006414) | 4.71658004 |
| 21 | protein targeting to ER (GO:0045047) | 4.64268544 |
| 22 | DNA damage response, detection of DNA damage (GO:0042769) | 4.53203279 |
| 23 | protein localization to endoplasmic reticulum (GO:0070972) | 4.49659137 |
| 24 | cellular protein complex disassembly (GO:0043624) | 4.48159937 |
| 25 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.46791581 |
| 26 | primitive streak formation (GO:0090009) | 4.32624741 |
| 27 | microtubule depolymerization (GO:0007019) | 4.31528395 |
| 28 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.20033699 |
| 29 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.06688029 |
| 30 | viral life cycle (GO:0019058) | 4.04218723 |
| 31 | protein complex disassembly (GO:0043241) | 3.95405010 |
| 32 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.89581673 |
| 33 | dopaminergic neuron differentiation (GO:0071542) | 3.86680881 |
| 34 | protein complex biogenesis (GO:0070271) | 3.80296940 |
| 35 | amyloid precursor protein catabolic process (GO:0042987) | 3.79658325 |
| 36 | ATP biosynthetic process (GO:0006754) | 3.79288685 |
| 37 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.79246043 |
| 38 | ribosomal small subunit biogenesis (GO:0042274) | 3.73106741 |
| 39 | macromolecular complex disassembly (GO:0032984) | 3.72054061 |
| 40 | negative regulation by host of viral transcription (GO:0043922) | 3.65125516 |
| 41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.64280315 |
| 42 | NADH dehydrogenase complex assembly (GO:0010257) | 3.64280315 |
| 43 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.64280315 |
| 44 | somite rostral/caudal axis specification (GO:0032525) | 3.63140483 |
| 45 | maturation of SSU-rRNA (GO:0030490) | 3.60714685 |
| 46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.59149461 |
| 47 | protein K6-linked ubiquitination (GO:0085020) | 3.58915849 |
| 48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.56102846 |
| 49 | translational initiation (GO:0006413) | 3.52519127 |
| 50 | regulation of activation of Janus kinase activity (GO:0010533) | 3.52295885 |
| 51 | chaperone-mediated protein transport (GO:0072321) | 3.42468995 |
| 52 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.37404551 |
| 53 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.34495639 |
| 54 | mannosylation (GO:0097502) | 3.33486700 |
| 55 | dorsal/ventral neural tube patterning (GO:0021904) | 3.32818583 |
| 56 | hydrogen ion transmembrane transport (GO:1902600) | 3.31749556 |
| 57 | regulation of cell-cell adhesion mediated by cadherin (GO:2000047) | 3.30787757 |
| 58 | regulation of autophagic vacuole assembly (GO:2000785) | 3.25718806 |
| 59 | inner mitochondrial membrane organization (GO:0007007) | 3.25071615 |
| 60 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.20221575 |
| 61 | DNA deamination (GO:0045006) | 3.19261417 |
| 62 | translation (GO:0006412) | 3.12610221 |
| 63 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.11980383 |
| 64 | proton transport (GO:0015992) | 3.11209529 |
| 65 | alkaloid metabolic process (GO:0009820) | 3.08953748 |
| 66 | positive regulation of male gonad development (GO:2000020) | 3.08051705 |
| 67 | negative T cell selection (GO:0043383) | 3.06985511 |
| 68 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.04853352 |
| 69 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.04853352 |
| 70 | hydrogen transport (GO:0006818) | 3.01869354 |
| 71 | axonemal dynein complex assembly (GO:0070286) | 3.01668930 |
| 72 | response to insecticide (GO:0017085) | 2.98209598 |
| 73 | GPI anchor metabolic process (GO:0006505) | 2.96580700 |
| 74 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.96082929 |
| 75 | indolalkylamine metabolic process (GO:0006586) | 2.94278947 |
| 76 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.93664416 |
| 77 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.92873505 |
| 78 | mRNA catabolic process (GO:0006402) | 2.91744178 |
| 79 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.90396304 |
| 80 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.87544756 |
| 81 | protein targeting to membrane (GO:0006612) | 2.86334248 |
| 82 | GPI anchor biosynthetic process (GO:0006506) | 2.85734930 |
| 83 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.83397509 |
| 84 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.83397509 |
| 85 | neural tube formation (GO:0001841) | 2.82349358 |
| 86 | negative regulation of B cell apoptotic process (GO:0002903) | 2.81114556 |
| 87 | midbrain development (GO:0030901) | 2.81002947 |
| 88 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.79419622 |
| 89 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.79419622 |
| 90 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.79419622 |
| 91 | negative thymic T cell selection (GO:0045060) | 2.73638710 |
| 92 | epithelial cilium movement (GO:0003351) | 2.73039892 |
| 93 | pseudouridine synthesis (GO:0001522) | 2.71724204 |
| 94 | regulation of male gonad development (GO:2000018) | 2.70543111 |
| 95 | eosinophil chemotaxis (GO:0048245) | 2.70059095 |
| 96 | ADP metabolic process (GO:0046031) | 2.69758682 |
| 97 | negative regulation of ligase activity (GO:0051352) | 2.69516115 |
| 98 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.69516115 |
| 99 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.68536833 |
| 100 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.68536833 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 7.93687085 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.55931937 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.89648867 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.42700802 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.20228063 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.16084888 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.04777633 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.97161376 |
| 9 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.87217766 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.85542691 |
| 11 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.65602744 |
| 12 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.46839155 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.25511197 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.23816510 |
| 15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.19048151 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.18434549 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.15992291 |
| 18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.12967140 |
| 19 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.08853317 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.06781922 |
| 21 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.02729018 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.94410596 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.88247404 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.85968338 |
| 25 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.81770535 |
| 26 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.78045228 |
| 27 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.77203287 |
| 28 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.71241224 |
| 29 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.67208881 |
| 30 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.66570939 |
| 31 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.63668447 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.61705511 |
| 33 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.60337048 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.55932495 |
| 35 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.53837549 |
| 36 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.53189119 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.50281951 |
| 38 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.44615739 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.44435753 |
| 40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.44394603 |
| 41 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.39634270 |
| 42 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.37399702 |
| 43 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.37199805 |
| 44 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.35690091 |
| 45 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.32315922 |
| 46 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.31545031 |
| 47 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.29085812 |
| 48 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.28494749 |
| 49 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.25530506 |
| 50 | * ERG_20517297_ChIP-Seq_VCAP_Human | 1.25047578 |
| 51 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.23513625 |
| 52 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.20493141 |
| 53 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.20232352 |
| 54 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.19701974 |
| 55 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.15515694 |
| 56 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.14318383 |
| 57 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.14225108 |
| 58 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.14169785 |
| 59 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.13618547 |
| 60 | ERA_21632823_ChIP-Seq_H3396_Human | 1.12934254 |
| 61 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.10731204 |
| 62 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10525120 |
| 63 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.10205544 |
| 64 | EWS_26573619_Chip-Seq_HEK293_Human | 1.09486210 |
| 65 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06498104 |
| 66 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.04709623 |
| 67 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.01796396 |
| 68 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01487743 |
| 69 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.99682697 |
| 70 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.97868970 |
| 71 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.97402266 |
| 72 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.97252167 |
| 73 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.96838323 |
| 74 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.96816414 |
| 75 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95023360 |
| 76 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93929436 |
| 77 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 0.93384872 |
| 78 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.91783515 |
| 79 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.91714518 |
| 80 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.91447534 |
| 81 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91179624 |
| 82 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.90491892 |
| 83 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.90329342 |
| 84 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.88679911 |
| 85 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.88447039 |
| 86 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.88178688 |
| 87 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87988408 |
| 88 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.87096651 |
| 89 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.82814446 |
| 90 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.82510597 |
| 91 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.82502964 |
| 92 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.80837435 |
| 93 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.80464883 |
| 94 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.77925227 |
| 95 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.77264214 |
| 96 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.76940856 |
| 97 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.76899644 |
| 98 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.76815189 |
| 99 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.76646351 |
| 100 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.75633958 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.43428990 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.56992459 |
| 3 | MP0002277_abnormal_respiratory_mucosa | 3.80728658 |
| 4 | MP0003011_delayed_dark_adaptation | 3.68991469 |
| 5 | MP0000569_abnormal_digit_pigmentation | 3.18190887 |
| 6 | MP0003136_yellow_coat_color | 2.83298167 |
| 7 | MP0003890_abnormal_embryonic-extraembry | 2.80433327 |
| 8 | MP0005084_abnormal_gallbladder_morpholo | 2.76868539 |
| 9 | MP0002102_abnormal_ear_morphology | 2.71121937 |
| 10 | MP0003283_abnormal_digestive_organ | 2.60341696 |
| 11 | MP0001188_hyperpigmentation | 2.47217071 |
| 12 | MP0004133_heterotaxia | 2.34517280 |
| 13 | MP0001529_abnormal_vocalization | 2.26128321 |
| 14 | MP0000372_irregular_coat_pigmentation | 2.12957034 |
| 15 | MP0003880_abnormal_central_pattern | 2.03538793 |
| 16 | MP0008961_abnormal_basal_metabolism | 2.00962003 |
| 17 | MP0002938_white_spotting | 1.87900959 |
| 18 | MP0008995_early_reproductive_senescence | 1.87069374 |
| 19 | MP0005671_abnormal_response_to | 1.83920045 |
| 20 | MP0001905_abnormal_dopamine_level | 1.83717092 |
| 21 | MP0001348_abnormal_lacrimal_gland | 1.75084970 |
| 22 | MP0002234_abnormal_pharynx_morphology | 1.61716172 |
| 23 | MP0002751_abnormal_autonomic_nervous | 1.61680039 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.60655851 |
| 25 | MP0005253_abnormal_eye_physiology | 1.57869042 |
| 26 | MP0002736_abnormal_nociception_after | 1.49076958 |
| 27 | MP0000049_abnormal_middle_ear | 1.47297005 |
| 28 | MP0002837_dystrophic_cardiac_calcinosis | 1.47126353 |
| 29 | MP0010030_abnormal_orbit_morphology | 1.46570576 |
| 30 | MP0000465_gastrointestinal_hemorrhage | 1.41594400 |
| 31 | MP0001293_anophthalmia | 1.39342638 |
| 32 | MP0000631_abnormal_neuroendocrine_gland | 1.35372435 |
| 33 | MP0003119_abnormal_digestive_system | 1.33503086 |
| 34 | MP0006072_abnormal_retinal_apoptosis | 1.32319302 |
| 35 | MP0008058_abnormal_DNA_repair | 1.27209730 |
| 36 | MP0005394_taste/olfaction_phenotype | 1.25198445 |
| 37 | MP0005499_abnormal_olfactory_system | 1.25198445 |
| 38 | MP0001485_abnormal_pinna_reflex | 1.24352761 |
| 39 | MP0004742_abnormal_vestibular_system | 1.18049685 |
| 40 | MP0009785_altered_susceptibility_to | 1.15164355 |
| 41 | MP0005379_endocrine/exocrine_gland_phen | 1.11453085 |
| 42 | MP0003806_abnormal_nucleotide_metabolis | 1.11290508 |
| 43 | MP0003866_abnormal_defecation | 1.06342779 |
| 44 | MP0000751_myopathy | 1.05394817 |
| 45 | MP0001968_abnormal_touch/_nociception | 1.04416219 |
| 46 | MP0003938_abnormal_ear_development | 1.04265457 |
| 47 | MP0002095_abnormal_skin_pigmentation | 1.03825480 |
| 48 | MP0000566_synostosis | 0.97684986 |
| 49 | MP0001879_abnormal_lymphatic_vessel | 0.95158808 |
| 50 | MP0002822_catalepsy | 0.95009725 |
| 51 | MP0002148_abnormal_hypersensitivity_rea | 0.93914898 |
| 52 | MP0001346_abnormal_lacrimal_gland | 0.90878246 |
| 53 | MP0002697_abnormal_eye_size | 0.90811366 |
| 54 | MP0004924_abnormal_behavior | 0.90177871 |
| 55 | MP0005386_behavior/neurological_phenoty | 0.90177871 |
| 56 | MP0009333_abnormal_splenocyte_physiolog | 0.89142028 |
| 57 | MP0006035_abnormal_mitochondrial_morpho | 0.88392255 |
| 58 | MP0005389_reproductive_system_phenotype | 0.87953548 |
| 59 | MP0001286_abnormal_eye_development | 0.86403850 |
| 60 | MP0008872_abnormal_physiological_respon | 0.85053236 |
| 61 | MP0004883_abnormal_blood_vessel | 0.84571274 |
| 62 | MP0005551_abnormal_eye_electrophysiolog | 0.84011771 |
| 63 | MP0001944_abnormal_pancreas_morphology | 0.83726680 |
| 64 | MP0005391_vision/eye_phenotype | 0.82303072 |
| 65 | MP0003878_abnormal_ear_physiology | 0.81615395 |
| 66 | MP0005377_hearing/vestibular/ear_phenot | 0.81615395 |
| 67 | MP0005000_abnormal_immune_tolerance | 0.81193438 |
| 68 | MP0002693_abnormal_pancreas_physiology | 0.79573102 |
| 69 | MP0001919_abnormal_reproductive_system | 0.79379565 |
| 70 | MP0006036_abnormal_mitochondrial_physio | 0.78582915 |
| 71 | MP0005423_abnormal_somatic_nervous | 0.78387709 |
| 72 | MP0002928_abnormal_bile_duct | 0.77018426 |
| 73 | MP0004142_abnormal_muscle_tone | 0.76889697 |
| 74 | MP0002282_abnormal_trachea_morphology | 0.76730741 |
| 75 | MP0005645_abnormal_hypothalamus_physiol | 0.76723445 |
| 76 | MP0001764_abnormal_homeostasis | 0.75522009 |
| 77 | MP0004145_abnormal_muscle_electrophysio | 0.72925744 |
| 78 | MP0003959_abnormal_lean_body | 0.72733759 |
| 79 | MP0000778_abnormal_nervous_system | 0.71309335 |
| 80 | MP0000647_abnormal_sebaceous_gland | 0.70217549 |
| 81 | MP0000026_abnormal_inner_ear | 0.70181924 |
| 82 | MP0003646_muscle_fatigue | 0.69610397 |
| 83 | MP0005636_abnormal_mineral_homeostasis | 0.67991955 |
| 84 | MP0002272_abnormal_nervous_system | 0.67105458 |
| 85 | MP0002160_abnormal_reproductive_system | 0.66935517 |
| 86 | MP0009053_abnormal_anal_canal | 0.66897658 |
| 87 | MP0003786_premature_aging | 0.66270096 |
| 88 | MP0005167_abnormal_blood-brain_barrier | 0.65403112 |
| 89 | MP0003186_abnormal_redox_activity | 0.64626073 |
| 90 | MP0004957_abnormal_blastocyst_morpholog | 0.62128315 |
| 91 | MP0008873_increased_physiological_sensi | 0.62117070 |
| 92 | MP0003937_abnormal_limbs/digits/tail_de | 0.61550455 |
| 93 | MP0001984_abnormal_olfaction | 0.58983999 |
| 94 | MP0002876_abnormal_thyroid_physiology | 0.58508906 |
| 95 | MP0003693_abnormal_embryo_hatching | 0.58120514 |
| 96 | MP0002163_abnormal_gland_morphology | 0.57984799 |
| 97 | MP0009697_abnormal_copulation | 0.56961416 |
| 98 | MP0005187_abnormal_penis_morphology | 0.56164138 |
| 99 | MP0001486_abnormal_startle_reflex | 0.54818821 |
| 100 | MP0003195_calcinosis | 0.53632208 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 5.12291812 |
| 2 | Hepatic necrosis (HP:0002605) | 4.86478236 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.71939327 |
| 4 | True hermaphroditism (HP:0010459) | 4.48153848 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.47425158 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 4.46142899 |
| 7 | Abnormal pupillary function (HP:0007686) | 4.01394512 |
| 8 | Supernumerary spleens (HP:0009799) | 3.95030664 |
| 9 | Increased CSF lactate (HP:0002490) | 3.79371918 |
| 10 | Hypothermia (HP:0002045) | 3.74511413 |
| 11 | Abnormal number of erythroid precursors (HP:0012131) | 3.72867965 |
| 12 | Abnormal ciliary motility (HP:0012262) | 3.67019466 |
| 13 | Acute encephalopathy (HP:0006846) | 3.63774195 |
| 14 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.52215016 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.50771429 |
| 16 | Increased intramyocellular lipid droplets (HP:0012240) | 3.46395658 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 3.42318620 |
| 18 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.26170230 |
| 19 | Cerebral edema (HP:0002181) | 3.20109207 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 3.11832707 |
| 21 | Short tibia (HP:0005736) | 3.10652911 |
| 22 | Absent septum pellucidum (HP:0001331) | 2.98158979 |
| 23 | Occipital encephalocele (HP:0002085) | 2.95669585 |
| 24 | Aplastic anemia (HP:0001915) | 2.94913977 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.89349168 |
| 26 | Lipid accumulation in hepatocytes (HP:0006561) | 2.86265371 |
| 27 | Septo-optic dysplasia (HP:0100842) | 2.84287947 |
| 28 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.81000465 |
| 29 | Pancreatic cysts (HP:0001737) | 2.79772191 |
| 30 | Limb dystonia (HP:0002451) | 2.79622959 |
| 31 | Chronic sinusitis (HP:0011109) | 2.75534178 |
| 32 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.75350871 |
| 33 | Increased muscle lipid content (HP:0009058) | 2.73548232 |
| 34 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.62323060 |
| 35 | Absent/shortened dynein arms (HP:0200106) | 2.62323060 |
| 36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.61805017 |
| 37 | Generalized aminoaciduria (HP:0002909) | 2.59614015 |
| 38 | Bilateral microphthalmos (HP:0007633) | 2.57339433 |
| 39 | Oral leukoplakia (HP:0002745) | 2.46861148 |
| 40 | Short middle phalanx of the 5th finger (HP:0004220) | 2.45690968 |
| 41 | Parakeratosis (HP:0001036) | 2.43032233 |
| 42 | Myokymia (HP:0002411) | 2.34091854 |
| 43 | Abnormal lung lobation (HP:0002101) | 2.32475512 |
| 44 | Molar tooth sign on MRI (HP:0002419) | 2.32095431 |
| 45 | Abnormality of midbrain morphology (HP:0002418) | 2.32095431 |
| 46 | 3-Methylglutaconic aciduria (HP:0003535) | 2.30752727 |
| 47 | Nephronophthisis (HP:0000090) | 2.30145756 |
| 48 | Type I transferrin isoform profile (HP:0003642) | 2.29050982 |
| 49 | Lactic acidosis (HP:0003128) | 2.28880874 |
| 50 | Abnormality of the septum pellucidum (HP:0007375) | 2.27468442 |
| 51 | Limb hypertonia (HP:0002509) | 2.24788878 |
| 52 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.23900610 |
| 53 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.22550795 |
| 54 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.22505313 |
| 55 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.22505313 |
| 56 | Sclerocornea (HP:0000647) | 2.19763361 |
| 57 | Anencephaly (HP:0002323) | 2.19015212 |
| 58 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.18667656 |
| 59 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.17884454 |
| 60 | Respiratory failure (HP:0002878) | 2.16748697 |
| 61 | Male pseudohermaphroditism (HP:0000037) | 2.16506871 |
| 62 | Optic disc pallor (HP:0000543) | 2.16369403 |
| 63 | Mesomelia (HP:0003027) | 2.14875561 |
| 64 | Macrocytic anemia (HP:0001972) | 2.13811131 |
| 65 | Sex reversal (HP:0012245) | 2.11115113 |
| 66 | Abnormal sex determination (HP:0012244) | 2.11115113 |
| 67 | Emotional lability (HP:0000712) | 2.09622834 |
| 68 | Reticulocytopenia (HP:0001896) | 2.08296441 |
| 69 | Increased serum lactate (HP:0002151) | 2.05395142 |
| 70 | Pendular nystagmus (HP:0012043) | 2.04189331 |
| 71 | Exercise intolerance (HP:0003546) | 2.03910591 |
| 72 | Pallor (HP:0000980) | 2.01583252 |
| 73 | Medial flaring of the eyebrow (HP:0010747) | 2.01179386 |
| 74 | Chronic otitis media (HP:0000389) | 1.99530139 |
| 75 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.98695694 |
| 76 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.98695694 |
| 77 | Median cleft lip (HP:0000161) | 1.97203557 |
| 78 | Congenital hepatic fibrosis (HP:0002612) | 1.97164404 |
| 79 | Sparse eyelashes (HP:0000653) | 1.96060392 |
| 80 | Maternal diabetes (HP:0009800) | 1.95838887 |
| 81 | Leukodystrophy (HP:0002415) | 1.94418559 |
| 82 | Exertional dyspnea (HP:0002875) | 1.91556321 |
| 83 | CNS demyelination (HP:0007305) | 1.90110687 |
| 84 | Renal cortical cysts (HP:0000803) | 1.89810799 |
| 85 | Cystic liver disease (HP:0006706) | 1.88088902 |
| 86 | Glycosuria (HP:0003076) | 1.85812424 |
| 87 | Abnormality of urine glucose concentration (HP:0011016) | 1.85812424 |
| 88 | Rhinitis (HP:0012384) | 1.84534486 |
| 89 | Hemivertebrae (HP:0002937) | 1.83220953 |
| 90 | Proximal tubulopathy (HP:0000114) | 1.82579875 |
| 91 | Bile duct proliferation (HP:0001408) | 1.82571230 |
| 92 | Abnormal biliary tract physiology (HP:0012439) | 1.82571230 |
| 93 | Abnormality of renal resorption (HP:0011038) | 1.81492249 |
| 94 | Preaxial hand polydactyly (HP:0001177) | 1.81440133 |
| 95 | Renal dysplasia (HP:0000110) | 1.80908285 |
| 96 | Abnormality of the renal medulla (HP:0100957) | 1.80165739 |
| 97 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.78072209 |
| 98 | Down-sloping shoulders (HP:0200021) | 1.77933832 |
| 99 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.76845236 |
| 100 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.76618240 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.66406230 |
| 2 | VRK1 | 3.52977529 |
| 3 | TLK1 | 3.24805628 |
| 4 | BUB1 | 3.18621090 |
| 5 | KDR | 3.18065106 |
| 6 | MAPK15 | 2.82726084 |
| 7 | CCNB1 | 2.65419230 |
| 8 | BRSK2 | 2.53292331 |
| 9 | BCKDK | 2.28066036 |
| 10 | ZAK | 2.22060225 |
| 11 | NME1 | 2.21435416 |
| 12 | ADRBK2 | 2.07272430 |
| 13 | PIM2 | 2.04866253 |
| 14 | MAPK13 | 2.00372790 |
| 15 | WEE1 | 1.97311797 |
| 16 | UHMK1 | 1.96550979 |
| 17 | TESK2 | 1.89457609 |
| 18 | PIK3CG | 1.51242666 |
| 19 | WNK3 | 1.50584905 |
| 20 | DYRK3 | 1.47028443 |
| 21 | TXK | 1.46945412 |
| 22 | PDK2 | 1.46205690 |
| 23 | EPHB2 | 1.39966706 |
| 24 | NTRK3 | 1.37922506 |
| 25 | PIM1 | 1.31415459 |
| 26 | NUAK1 | 1.29829721 |
| 27 | GRK1 | 1.27730874 |
| 28 | RPS6KA5 | 1.18475982 |
| 29 | GRK6 | 1.18475259 |
| 30 | DYRK2 | 1.17959073 |
| 31 | SRPK1 | 1.16742477 |
| 32 | PNCK | 1.14790743 |
| 33 | BRSK1 | 1.11922766 |
| 34 | MAP3K10 | 1.10691417 |
| 35 | OBSCN | 1.09751004 |
| 36 | WNK4 | 1.09081521 |
| 37 | STK16 | 1.07893085 |
| 38 | MARK1 | 1.03862086 |
| 39 | NEK1 | 0.98745709 |
| 40 | MAP2K7 | 0.97772013 |
| 41 | GRK7 | 0.96515458 |
| 42 | PASK | 0.94366916 |
| 43 | TESK1 | 0.91074927 |
| 44 | PLK3 | 0.83495502 |
| 45 | DYRK1B | 0.81832353 |
| 46 | CHUK | 0.80597698 |
| 47 | TRIM28 | 0.80383334 |
| 48 | MUSK | 0.76590098 |
| 49 | DYRK1A | 0.75140092 |
| 50 | CDK3 | 0.74692268 |
| 51 | RPS6KA4 | 0.74469739 |
| 52 | PBK | 0.74199917 |
| 53 | MAPK4 | 0.73835665 |
| 54 | PLK1 | 0.71566169 |
| 55 | TIE1 | 0.70885256 |
| 56 | PIK3CA | 0.70747238 |
| 57 | INSRR | 0.70655873 |
| 58 | MAP3K11 | 0.69830394 |
| 59 | AURKA | 0.69830078 |
| 60 | LRRK2 | 0.67440127 |
| 61 | PTK2B | 0.67190311 |
| 62 | PRKCG | 0.66762346 |
| 63 | PRKCQ | 0.64903851 |
| 64 | NEK2 | 0.64165408 |
| 65 | AURKB | 0.63505411 |
| 66 | PAK1 | 0.61804872 |
| 67 | PRKACA | 0.59808831 |
| 68 | MAP3K4 | 0.58702326 |
| 69 | MAP4K2 | 0.57816530 |
| 70 | IKBKE | 0.57496670 |
| 71 | ARAF | 0.48582026 |
| 72 | IKBKB | 0.48466217 |
| 73 | EIF2AK1 | 0.47692360 |
| 74 | NEK9 | 0.47514874 |
| 75 | BMPR1B | 0.47452273 |
| 76 | CSNK2A1 | 0.46652584 |
| 77 | CSNK2A2 | 0.46624263 |
| 78 | CAMK2B | 0.46558875 |
| 79 | PHKG2 | 0.46208874 |
| 80 | PHKG1 | 0.46208874 |
| 81 | MKNK1 | 0.45171362 |
| 82 | CSNK1G1 | 0.43664705 |
| 83 | ITK | 0.43397213 |
| 84 | DAPK3 | 0.41701838 |
| 85 | LIMK1 | 0.41495536 |
| 86 | LCK | 0.40937812 |
| 87 | PRKCB | 0.40675202 |
| 88 | MAP3K5 | 0.39945899 |
| 89 | CSNK1G2 | 0.39709851 |
| 90 | BRAF | 0.38938525 |
| 91 | MAP4K1 | 0.38740683 |
| 92 | MAPK7 | 0.37865630 |
| 93 | MATK | 0.37737173 |
| 94 | ABL2 | 0.37400060 |
| 95 | ADRBK1 | 0.37198832 |
| 96 | TBK1 | 0.36395157 |
| 97 | EPHA4 | 0.36075069 |
| 98 | TNIK | 0.35074652 |
| 99 | MST4 | 0.33422800 |
| 100 | FES | 0.32774071 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 5.32800944 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 5.12729687 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 4.52672242 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.72079343 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 3.16351397 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 3.14494599 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.93987763 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.81261135 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.64086150 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.35446064 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.28099990 |
| 12 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.09250365 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.03049729 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.86178461 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 1.80887577 |
| 16 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.57771695 |
| 17 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.55850933 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.52154348 |
| 19 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.40084564 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.39106280 |
| 21 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.35447213 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.34261247 |
| 23 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.23357616 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.16482627 |
| 25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.15612344 |
| 26 | Protein export_Homo sapiens_hsa03060 | 1.12077384 |
| 27 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.07110949 |
| 28 | DNA replication_Homo sapiens_hsa03030 | 1.06436629 |
| 29 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.05735616 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.04659568 |
| 31 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.00724030 |
| 32 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.99620846 |
| 33 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.99562442 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 0.97588152 |
| 35 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.97123527 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.96758862 |
| 37 | Mismatch repair_Homo sapiens_hsa03430 | 0.95322696 |
| 38 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.93357891 |
| 39 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.91017089 |
| 40 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.83282417 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.79480410 |
| 42 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.79355125 |
| 43 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.77334585 |
| 44 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.75924130 |
| 45 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.75579173 |
| 46 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.75253454 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.73054873 |
| 48 | Histidine metabolism_Homo sapiens_hsa00340 | 0.67509968 |
| 49 | Allograft rejection_Homo sapiens_hsa05330 | 0.66457105 |
| 50 | RNA transport_Homo sapiens_hsa03013 | 0.66109131 |
| 51 | Alcoholism_Homo sapiens_hsa05034 | 0.63681298 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.61727867 |
| 53 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.60590886 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60024829 |
| 55 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59221429 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.58297230 |
| 57 | Phototransduction_Homo sapiens_hsa04744 | 0.56601756 |
| 58 | Base excision repair_Homo sapiens_hsa03410 | 0.52791745 |
| 59 | Phagosome_Homo sapiens_hsa04145 | 0.51585072 |
| 60 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51250620 |
| 61 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.51218111 |
| 62 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.51071478 |
| 63 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.49191515 |
| 64 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.44304991 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43696315 |
| 66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.43544671 |
| 67 | Gap junction_Homo sapiens_hsa04540 | 0.41538487 |
| 68 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40957094 |
| 69 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.40319177 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.40280667 |
| 71 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.39033120 |
| 72 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38721559 |
| 73 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.37920547 |
| 74 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37841107 |
| 75 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.37756535 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.37161436 |
| 77 | Salmonella infection_Homo sapiens_hsa05132 | 0.36356839 |
| 78 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.35299054 |
| 79 | Olfactory transduction_Homo sapiens_hsa04740 | 0.34684311 |
| 80 | Basal transcription factors_Homo sapiens_hsa03022 | 0.33979225 |
| 81 | Cocaine addiction_Homo sapiens_hsa05030 | 0.33522025 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.32635047 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32627882 |
| 84 | Asthma_Homo sapiens_hsa05310 | 0.32343333 |
| 85 | ABC transporters_Homo sapiens_hsa02010 | 0.31883480 |
| 86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.30247527 |
| 87 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.29768726 |
| 88 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.28547085 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.27247890 |
| 90 | Sulfur relay system_Homo sapiens_hsa04122 | 0.24574577 |
| 91 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.24130483 |
| 92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.23902449 |
| 93 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.21997753 |
| 94 | Malaria_Homo sapiens_hsa05144 | 0.20994471 |
| 95 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.20837986 |
| 96 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.18922537 |
| 97 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.18378099 |
| 98 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.17500875 |
| 99 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.16757142 |
| 100 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.16470064 |

