RNGTT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore complex assembly (GO:0051292)5.96559914
2nuclear pore organization (GO:0006999)5.51403828
3pore complex assembly (GO:0046931)4.94545138
4mitotic sister chromatid cohesion (GO:0007064)4.83179852
5regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.39763794
6double-strand break repair via nonhomologous end joining (GO:0006303)4.15172300
7non-recombinational repair (GO:0000726)4.15172300
8somatic diversification of immune receptors via somatic mutation (GO:0002566)4.11708894
9somatic hypermutation of immunoglobulin genes (GO:0016446)4.11708894
10sister chromatid segregation (GO:0000819)4.05774097
11mitotic sister chromatid segregation (GO:0000070)3.95657348
12protein localization to kinetochore (GO:0034501)3.95195005
13kinetochore organization (GO:0051383)3.93519764
14kinetochore assembly (GO:0051382)3.88666909
15mitotic spindle checkpoint (GO:0071174)3.87032907
16DNA replication-dependent nucleosome organization (GO:0034723)3.85672265
17DNA replication-dependent nucleosome assembly (GO:0006335)3.85672265
18negative regulation of mitotic sister chromatid separation (GO:2000816)3.77202328
19negative regulation of sister chromatid segregation (GO:0033046)3.77202328
20negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.77202328
21negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.77202328
22negative regulation of chromosome segregation (GO:0051985)3.76361758
23regulation of mitotic metaphase/anaphase transition (GO:0030071)3.76048443
24regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.76048443
25mitotic nuclear envelope disassembly (GO:0007077)3.75747043
26protein localization to chromosome, centromeric region (GO:0071459)3.72319887
27regulation of sister chromatid segregation (GO:0033045)3.66800181
28regulation of mitotic sister chromatid separation (GO:0010965)3.66800181
29regulation of mitotic sister chromatid segregation (GO:0033047)3.66800181
30regulation of chromosome segregation (GO:0051983)3.66258820
31mitotic spindle assembly checkpoint (GO:0007094)3.65793565
32histone H2A acetylation (GO:0043968)3.64945987
33regulation of centriole replication (GO:0046599)3.62247178
34spindle assembly checkpoint (GO:0071173)3.61904518
35regulation of nuclear cell cycle DNA replication (GO:0033262)3.53281421
36postreplication repair (GO:0006301)3.52339279
37positive regulation of mitotic sister chromatid separation (GO:1901970)3.52101340
38positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.52101340
39positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.52101340
40nuclear envelope disassembly (GO:0051081)3.50502946
41membrane disassembly (GO:0030397)3.50502946
42negative regulation of DNA-dependent DNA replication (GO:2000104)3.46438083
43positive regulation of chromosome segregation (GO:0051984)3.44482431
44DNA deamination (GO:0045006)3.43449374
45negative regulation of DNA recombination (GO:0045910)3.43045916
46DNA geometric change (GO:0032392)3.41286508
47telomere maintenance via semi-conservative replication (GO:0032201)3.40236343
48mitotic chromosome condensation (GO:0007076)3.39401606
49DNA topological change (GO:0006265)3.37875030
50ribosome assembly (GO:0042255)3.37690349
51DNA duplex unwinding (GO:0032508)3.34052759
52telomere maintenance via recombination (GO:0000722)3.33471116
53CENP-A containing nucleosome assembly (GO:0034080)3.33320349
54regulation of sister chromatid cohesion (GO:0007063)3.31862644
55DNA unwinding involved in DNA replication (GO:0006268)3.30471201
56establishment of integrated proviral latency (GO:0075713)3.26227334
57protein localization to chromosome (GO:0034502)3.20953742
58microtubule depolymerization (GO:0007019)3.19838088
59regulation of centrosome cycle (GO:0046605)3.19365972
60ATP-dependent chromatin remodeling (GO:0043044)3.19068716
61DNA replication checkpoint (GO:0000076)3.14430223
62chromatin remodeling at centromere (GO:0031055)3.13803665
63regulation of centrosome duplication (GO:0010824)3.13388820
64somatic cell DNA recombination (GO:0016444)3.13138263
65somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.13138263
66regulation of mitotic spindle checkpoint (GO:1903504)3.11785204
67regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.11785204
68DNA double-strand break processing (GO:0000729)3.11621988
69mitotic recombination (GO:0006312)3.10780244
70translesion synthesis (GO:0019985)3.10081634
71pre-miRNA processing (GO:0031054)3.09822753
72negative regulation of mRNA processing (GO:0050686)3.08220434
73DNA replication initiation (GO:0006270)3.08096829
74maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.07661214
75meiotic chromosome segregation (GO:0045132)3.07181879
76mitochondrial DNA replication (GO:0006264)3.06832456
77somatic diversification of immune receptors (GO:0002200)2.99270539
78response to X-ray (GO:0010165)2.98651575
79DNA strand elongation involved in DNA replication (GO:0006271)2.98402612
80deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.96353322
81DNA strand elongation (GO:0022616)2.96009748
82replication fork processing (GO:0031297)2.94754757
83telomere maintenance via telomere lengthening (GO:0010833)2.94735631
84regulation of helicase activity (GO:0051095)2.91595591
85DNA catabolic process, exonucleolytic (GO:0000738)2.90360018
86antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.88967719
87DNA synthesis involved in DNA repair (GO:0000731)2.87007685
88DNA replication-independent nucleosome organization (GO:0034724)2.85723869
89DNA replication-independent nucleosome assembly (GO:0006336)2.85723869
90tRNA methylation (GO:0030488)2.84896015
91termination of RNA polymerase III transcription (GO:0006386)2.82831960
92transcription elongation from RNA polymerase III promoter (GO:0006385)2.82831960
93transcription elongation from RNA polymerase I promoter (GO:0006362)2.82820705
94DNA strand renaturation (GO:0000733)2.81879861
95mismatch repair (GO:0006298)2.79991802
96termination of RNA polymerase I transcription (GO:0006363)2.78336330
97regulation of double-strand break repair via homologous recombination (GO:0010569)2.76319352
98centriole assembly (GO:0098534)2.72036067
99intra-S DNA damage checkpoint (GO:0031573)2.70078999
100nucleotide-excision repair, DNA gap filling (GO:0006297)2.69899176
101mitotic metaphase plate congression (GO:0007080)2.67940431
102telomere maintenance (GO:0000723)2.64308695
103protein K6-linked ubiquitination (GO:0085020)2.62238010
104telomere organization (GO:0032200)2.61282692
105DNA-dependent DNA replication (GO:0006261)2.56821279
106proteasome assembly (GO:0043248)2.53593866
107regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.53264706
108DNA integration (GO:0015074)2.52747571
109metaphase plate congression (GO:0051310)2.51251223
110transcription-coupled nucleotide-excision repair (GO:0006283)2.50885187
111regulation of DNA endoreduplication (GO:0032875)2.48248580
112polyketide metabolic process (GO:0030638)2.47844725
113doxorubicin metabolic process (GO:0044598)2.47844725
114daunorubicin metabolic process (GO:0044597)2.47844725
115histone exchange (GO:0043486)2.47232127
116positive regulation of defense response to virus by host (GO:0002230)2.44215563
117regulation of activation of Janus kinase activity (GO:0010533)2.43868530
118transcription from RNA polymerase I promoter (GO:0006360)2.42722796
119negative regulation of mast cell activation (GO:0033004)2.38386360
120ribosomal small subunit assembly (GO:0000028)2.38284494
121* RNA capping (GO:0036260)2.37735332
122* 7-methylguanosine RNA capping (GO:0009452)2.37735332
123DNA ligation (GO:0006266)2.37573862
124centriole replication (GO:0007099)2.37091442
125transcription initiation from RNA polymerase I promoter (GO:0006361)2.36977048
126recombinational repair (GO:0000725)2.36938803
127telomere maintenance via telomerase (GO:0007004)2.36840834
128isotype switching (GO:0045190)2.36272915
129somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.36272915
130somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.36272915
131RNA-dependent DNA replication (GO:0006278)2.35397393
132viral mRNA export from host cell nucleus (GO:0046784)2.35234805
133establishment of chromosome localization (GO:0051303)2.34395957
134RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.33720791
135tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.33720791
136* 7-methylguanosine mRNA capping (GO:0006370)2.32162100
137lymphoid progenitor cell differentiation (GO:0002320)2.32059754
138tRNA modification (GO:0006400)2.30829116
139double-strand break repair via homologous recombination (GO:0000724)2.30382263
140pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.29794782
141adenosine metabolic process (GO:0046085)2.28772267
142interferon-gamma production (GO:0032609)2.28635646
143attachment of spindle microtubules to kinetochore (GO:0008608)2.28066586
144nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.26866601
145exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.26547915
146DNA recombination (GO:0006310)2.25783140
147regulation of histone H3-K27 methylation (GO:0061085)2.24967601
148spindle checkpoint (GO:0031577)2.24059960
149somatic recombination of immunoglobulin gene segments (GO:0016447)2.23648483
150reciprocal DNA recombination (GO:0035825)2.21592958
151reciprocal meiotic recombination (GO:0007131)2.21592958
152pyrimidine dimer repair (GO:0006290)2.21404722
153somatic diversification of immunoglobulins (GO:0016445)2.20932510
154nucleotide-excision repair (GO:0006289)2.20847206
155DNA replication (GO:0006260)2.20573860
156regulation of DNA recombination (GO:0000018)2.20195110
157replicative senescence (GO:0090399)2.19636638
158tRNA processing (GO:0008033)2.18681630
159microtubule polymerization or depolymerization (GO:0031109)2.18672250
160negative regulation of mitotic sister chromatid segregation (GO:0033048)2.17780251

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.71475572
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.27058474
3E2F4_17652178_ChIP-ChIP_JURKAT_Human3.10101378
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.81588428
5ELF1_17652178_ChIP-ChIP_JURKAT_Human2.72250205
6HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.64110573
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.63781000
8MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.47531628
9TP63_19390658_ChIP-ChIP_HaCaT_Human2.32901663
10GABP_17652178_ChIP-ChIP_JURKAT_Human2.27963064
11IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.21344276
12FLI1_27457419_Chip-Seq_LIVER_Mouse2.14418250
13IRF8_21731497_ChIP-ChIP_J774_Mouse2.12621223
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.11560678
15PCGF2_27294783_Chip-Seq_ESCs_Mouse2.10275685
16CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.09691796
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.04865139
18AR_21909140_ChIP-Seq_LNCAP_Human2.03107281
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.94742081
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.92365970
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90563144
22FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.89071517
23* ELK1_19687146_ChIP-ChIP_HELA_Human1.86614715
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.86142984
25VDR_23849224_ChIP-Seq_CD4+_Human1.85232640
26BP1_19119308_ChIP-ChIP_Hs578T_Human1.83956626
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.78595072
28SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.75843705
29NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.72244113
30ZFP57_27257070_Chip-Seq_ESCs_Mouse1.70396666
31POU3F2_20337985_ChIP-ChIP_501MEL_Human1.70238709
32EWS_26573619_Chip-Seq_HEK293_Human1.67615150
33IRF1_19129219_ChIP-ChIP_H3396_Human1.66937281
34MYC_18555785_ChIP-Seq_MESCs_Mouse1.62690236
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.62463426
36IRF8_22096565_ChIP-ChIP_GC-B_Human1.59983554
37FOXP3_21729870_ChIP-Seq_TREG_Human1.59380386
38SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.59246403
39SALL1_21062744_ChIP-ChIP_HESCs_Human1.58607814
40MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.58412249
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58088194
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.57625890
43FUS_26573619_Chip-Seq_HEK293_Human1.57259220
44* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.57085898
45MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53990382
46CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.53968087
47DCP1A_22483619_ChIP-Seq_HELA_Human1.53566467
48FOXM1_23109430_ChIP-Seq_U2OS_Human1.53245474
49HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.52729157
50GBX2_23144817_ChIP-Seq_PC3_Human1.52466326
51HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.51861999
52TAF15_26573619_Chip-Seq_HEK293_Human1.50928990
53* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49110254
54* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.48402900
55* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.45529300
56SUZ12_27294783_Chip-Seq_NPCs_Mouse1.45479998
57BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.45381148
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.43706169
59* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.43410284
60NFE2_27457419_Chip-Seq_LIVER_Mouse1.42873227
61IGF1R_20145208_ChIP-Seq_DFB_Human1.41552365
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.39395177
63POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.39008347
64ZNF274_21170338_ChIP-Seq_K562_Hela1.37995203
65POU5F1_16153702_ChIP-ChIP_HESCs_Human1.36185818
66E2F1_21310950_ChIP-Seq_MCF-7_Human1.34112810
67ETS1_20019798_ChIP-Seq_JURKAT_Human1.34067634
68MYC_19030024_ChIP-ChIP_MESCs_Mouse1.29527397
69EZH2_27294783_Chip-Seq_NPCs_Mouse1.26729858
70GABP_19822575_ChIP-Seq_HepG2_Human1.25620203
71SMAD_19615063_ChIP-ChIP_OVARY_Human1.23926682
72SUZ12_18555785_Chip-Seq_ESCs_Mouse1.23680718
73* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22649015
74STAT3_18555785_Chip-Seq_ESCs_Mouse1.22603090
75* NMYC_18555785_Chip-Seq_ESCs_Mouse1.22174640
76STAT4_19710469_ChIP-ChIP_TH1__Mouse1.21704902
77FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.20854998
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.20120768
79IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.18955642
80CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.18206189
81E2F1_18555785_Chip-Seq_ESCs_Mouse1.18018088
82MYC_19079543_ChIP-ChIP_MESCs_Mouse1.17233553
83STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.16419134
84* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.16185102
85EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.15868627
86ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.14272541
87P300_18555785_Chip-Seq_ESCs_Mouse1.13985059
88MYC_18358816_ChIP-ChIP_MESCs_Mouse1.12656361
89* SPI1_23547873_ChIP-Seq_NB4_Human1.12501506
90* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.11089058
91* P300_19829295_ChIP-Seq_ESCs_Human1.10983117
92* TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.10580975
93EGR1_19374776_ChIP-ChIP_THP-1_Human1.10556600
94CMYC_18555785_Chip-Seq_ESCs_Mouse1.09574734
95P53_22387025_ChIP-Seq_ESCs_Mouse1.09079167
96PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.09043790
97PADI4_21655091_ChIP-ChIP_MCF-7_Human1.08486090
98* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.08132069
99RUNX1_27457419_Chip-Seq_LIVER_Mouse1.06831178
100VDR_22108803_ChIP-Seq_LS180_Human1.06449451
101OCT4_18555785_Chip-Seq_ESCs_Mouse1.06226385
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06035217
103THAP11_20581084_ChIP-Seq_MESCs_Mouse1.05811723
104BMI1_23680149_ChIP-Seq_NPCS_Mouse1.05185600
105ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.04973501
106MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.04482493
107MYC_18940864_ChIP-ChIP_HL60_Human1.04325829
108RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.03450144
109YY1_21170310_ChIP-Seq_MESCs_Mouse1.02823944
110ZFX_18555785_ChIP-Seq_MESCs_Mouse1.02690631
111EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.02558975
112ZFX_18555785_Chip-Seq_ESCs_Mouse1.02044611
113SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.01761274
114SOX2_18555785_Chip-Seq_ESCs_Mouse1.01755338
115SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.01755063
116KLF4_18555785_Chip-Seq_ESCs_Mouse1.00079032
117TTF2_22483619_ChIP-Seq_HELA_Human0.98986691
118KDM5A_27292631_Chip-Seq_BREAST_Human0.98776958
119NELFA_20434984_ChIP-Seq_ESCs_Mouse0.98175008
120* CREB1_15753290_ChIP-ChIP_HEK293T_Human0.98036115
121RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.97672879
122AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.97142637
123CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.96323826
124RNF2_27304074_Chip-Seq_NSC_Mouse0.96197942
125MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95817046
126GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95588064
127PU1_27457419_Chip-Seq_LIVER_Mouse0.95047522
128ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.94530839
129SMAD1_18555785_Chip-Seq_ESCs_Mouse0.93645184
130CTCF_18555785_Chip-Seq_ESCs_Mouse0.93484729
131NANOG_16153702_ChIP-ChIP_HESCs_Human0.92333149
132WT1_19549856_ChIP-ChIP_CCG9911_Human0.91281712
133OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90601285
134SOX2_16153702_ChIP-ChIP_HESCs_Human0.90533760
135DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.90262994
136XRN2_22483619_ChIP-Seq_HELA_Human0.89663057
137CIITA_25753668_ChIP-Seq_RAJI_Human0.88273362
138TFEB_21752829_ChIP-Seq_HELA_Human0.87667643
139TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87542664
140SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.85950315
141SOX9_26525672_Chip-Seq_HEART_Mouse0.81522163
142CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.80582628

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008058_abnormal_DNA_repair3.45796837
2MP0008057_abnormal_DNA_replication3.41267594
3MP0006292_abnormal_olfactory_placode2.98038270
4MP0010094_abnormal_chromosome_stability2.87156195
5MP0003693_abnormal_embryo_hatching2.72844723
6MP0001188_hyperpigmentation2.43327341
7MP0001835_abnormal_antigen_presentation2.38998632
8MP0000566_synostosis2.36453332
9MP0008877_abnormal_DNA_methylation2.32266978
10MP0003111_abnormal_nucleus_morphology2.28605775
11MP0005671_abnormal_response_to2.25012441
12MP0003787_abnormal_imprinting2.22055607
13MP0001986_abnormal_taste_sensitivity2.16784084
14MP0000015_abnormal_ear_pigmentation2.12276016
15MP0003077_abnormal_cell_cycle2.10627049
16MP0002102_abnormal_ear_morphology2.03908405
17MP0010352_gastrointestinal_tract_polyps2.01266318
18MP0003763_abnormal_thymus_physiology1.99366664
19MP0008007_abnormal_cellular_replicative1.95954628
20MP0004381_abnormal_hair_follicle1.92254988
21MP0003221_abnormal_cardiomyocyte_apopto1.86197633
22MP0003136_yellow_coat_color1.81175775
23MP0003567_abnormal_fetal_cardiomyocyte1.78162044
24MP0010307_abnormal_tumor_latency1.77601565
25MP0005075_abnormal_melanosome_morpholog1.77376612
26MP0002148_abnormal_hypersensitivity_rea1.76593576
27MP0002396_abnormal_hematopoietic_system1.74175280
28MP0005174_abnormal_tail_pigmentation1.73214417
29MP0002277_abnormal_respiratory_mucosa1.70402214
30MP0001730_embryonic_growth_arrest1.68091741
31MP0002095_abnormal_skin_pigmentation1.67821432
32MP0000372_irregular_coat_pigmentation1.60483105
33MP0006035_abnormal_mitochondrial_morpho1.59173989
34MP0000569_abnormal_digit_pigmentation1.59104087
35MP0003786_premature_aging1.57915154
36MP0001697_abnormal_embryo_size1.57794367
37MP0009785_altered_susceptibility_to1.56366923
38MP0009697_abnormal_copulation1.51234672
39MP0001800_abnormal_humoral_immune1.46039884
40MP0005000_abnormal_immune_tolerance1.44162505
41MP0001672_abnormal_embryogenesis/_devel1.44027563
42MP0005380_embryogenesis_phenotype1.44027563
43MP0002163_abnormal_gland_morphology1.43876229
44MP0008932_abnormal_embryonic_tissue1.39745587
45MP0005171_absent_coat_pigmentation1.38797281
46MP0002452_abnormal_antigen_presenting1.37934544
47MP0002723_abnormal_immune_serum1.37524805
48MP0002420_abnormal_adaptive_immunity1.35784742
49MP0010234_abnormal_vibrissa_follicle1.35656667
50MP0001819_abnormal_immune_cell1.35266095
51MP0002398_abnormal_bone_marrow1.34763119
52MP0003121_genomic_imprinting1.34660615
53MP0002084_abnormal_developmental_patter1.34262213
54MP0004197_abnormal_fetal_growth/weight/1.34073881
55MP0005187_abnormal_penis_morphology1.33067392
56MP0002132_abnormal_respiratory_system1.32413987
57MP0003984_embryonic_growth_retardation1.30480252
58MP0008260_abnormal_autophagy1.28983391
59MP0002938_white_spotting1.27507778
60MP0002088_abnormal_embryonic_growth/wei1.26766528
61MP0004957_abnormal_blastocyst_morpholog1.23330640
62MP0001790_abnormal_immune_system1.22886822
63MP0005387_immune_system_phenotype1.22886822
64MP0000490_abnormal_crypts_of1.22845949
65MP0005025_abnormal_response_to1.22458711
66MP0002638_abnormal_pupillary_reflex1.21174078
67MP0002080_prenatal_lethality1.20599189
68MP0000716_abnormal_immune_system1.17188664
69MP0000358_abnormal_cell_content/1.16432613
70MP0002419_abnormal_innate_immunity1.15862266
71MP0005409_darkened_coat_color1.15747794
72MP0002090_abnormal_vision1.14579269
73MP0002085_abnormal_embryonic_tissue1.13815898
74MP0009672_abnormal_birth_weight1.13283228
75MP0005645_abnormal_hypothalamus_physiol1.12879346
76MP0000703_abnormal_thymus_morphology1.10713041
77MP0009333_abnormal_splenocyte_physiolog1.10610904
78MP0009703_decreased_birth_body1.09765219
79MP0005423_abnormal_somatic_nervous1.09691034
80MP0003724_increased_susceptibility_to1.07458747
81MP0004808_abnormal_hematopoietic_stem1.05825031
82MP0003718_maternal_effect1.05743434
83MP0000647_abnormal_sebaceous_gland1.04681518
84MP0003943_abnormal_hepatobiliary_system1.04050178
85MP0000685_abnormal_immune_system1.02609947
86MP0005379_endocrine/exocrine_gland_phen1.00490188
87MP0005310_abnormal_salivary_gland0.99542367
88MP0002009_preneoplasia0.99290447
89MP0002086_abnormal_extraembryonic_tissu0.98601321
90MP0002722_abnormal_immune_system0.97955890
91MP0001286_abnormal_eye_development0.97830948
92MP0001186_pigmentation_phenotype0.97041940
93MP0002429_abnormal_blood_cell0.95720639
94MP0000689_abnormal_spleen_morphology0.94424387
95MP0002928_abnormal_bile_duct0.94388116
96MP0000383_abnormal_hair_follicle0.93713939
97MP0005384_cellular_phenotype0.91428052
98MP0002210_abnormal_sex_determination0.91274221
99MP0002751_abnormal_autonomic_nervous0.90723459
100MP0002160_abnormal_reproductive_system0.89515694
101MP0001929_abnormal_gametogenesis0.87886932
102MP0003880_abnormal_central_pattern0.87590527
103MP0004742_abnormal_vestibular_system0.85762176
104MP0008789_abnormal_olfactory_epithelium0.85267720
105MP0005391_vision/eye_phenotype0.84227444
106MP0005389_reproductive_system_phenotype0.83863449
107MP0005084_abnormal_gallbladder_morpholo0.83168900
108MP0002405_respiratory_system_inflammati0.82978282
109MP0002233_abnormal_nose_morphology0.82472374
110MP0005646_abnormal_pituitary_gland0.82251910
111MP0001177_atelectasis0.81427187
112MP0003941_abnormal_skin_development0.81139749
113MP0001485_abnormal_pinna_reflex0.80945679
114MP0001145_abnormal_male_reproductive0.80005238
115MP0001119_abnormal_female_reproductive0.79561470
116MP0003937_abnormal_limbs/digits/tail_de0.79406781
117MP0010678_abnormal_skin_adnexa0.79256064
118MP0001529_abnormal_vocalization0.78654322
119MP0001293_anophthalmia0.78360999
120MP0005253_abnormal_eye_physiology0.78202283
121MP0003890_abnormal_embryonic-extraembry0.77290364
122MP0002092_abnormal_eye_morphology0.76677103
123MP0000313_abnormal_cell_death0.76253626
124MP0005621_abnormal_cell_physiology0.75891289
125MP0002075_abnormal_coat/hair_pigmentati0.75592372
126MP0002697_abnormal_eye_size0.74641086
127MP0000428_abnormal_craniofacial_morphol0.74488621
128MP0003866_abnormal_defecation0.74442846
129MP0000653_abnormal_sex_gland0.74216992
130MP0003755_abnormal_palate_morphology0.73939652
131MP0002006_tumorigenesis0.71875206
132MP0010155_abnormal_intestine_physiology0.71414658
133MP0006072_abnormal_retinal_apoptosis0.71054007
134MP0005394_taste/olfaction_phenotype0.70664836
135MP0005499_abnormal_olfactory_system0.70664836
136MP0000427_abnormal_hair_cycle0.70261819
137MP0003861_abnormal_nervous_system0.70142599
138MP0000371_diluted_coat_color0.70108426
139MP0008995_early_reproductive_senescence0.69970499
140MP0001346_abnormal_lacrimal_gland0.69765395
141MP0006276_abnormal_autonomic_nervous0.69614675
142MP0003436_decreased_susceptibility_to0.68015304
143MP0002019_abnormal_tumor_incidence0.66853120
144MP0000350_abnormal_cell_proliferation0.66661851
145MP0005367_renal/urinary_system_phenotyp0.66091227
146MP0000516_abnormal_urinary_system0.66091227
147MP0002111_abnormal_tail_morphology0.65854320
148MP0002177_abnormal_outer_ear0.65588879
149MP0000631_abnormal_neuroendocrine_gland0.65551448
150MP0001919_abnormal_reproductive_system0.64507941
151MP0001324_abnormal_eye_pigmentation0.62841626

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.49564994
2Chromsome breakage (HP:0040012)5.30806683
3Abnormality of chromosome stability (HP:0003220)3.67775320
4Duplicated collecting system (HP:0000081)3.66488808
5Volvulus (HP:0002580)3.66225249
6Birth length less than 3rd percentile (HP:0003561)3.57504419
7Aplasia/Hypoplasia of the uvula (HP:0010293)3.56454831
8Abnormality of the preputium (HP:0100587)3.55743368
9Abnormality of the renal collecting system (HP:0004742)3.45273365
10Meckel diverticulum (HP:0002245)3.44455074
11Abnormality of the ileum (HP:0001549)3.27495834
12Rhabdomyosarcoma (HP:0002859)3.27400335
13Colon cancer (HP:0003003)3.22860821
14Abnormality of DNA repair (HP:0003254)3.22037264
15Clubbing of toes (HP:0100760)3.11623144
16Cortical dysplasia (HP:0002539)3.00487537
17Ependymoma (HP:0002888)2.96555819
18Glioma (HP:0009733)2.75935681
19Ectopic kidney (HP:0000086)2.67107362
20Papillary thyroid carcinoma (HP:0002895)2.63213177
21Small intestinal stenosis (HP:0012848)2.63050624
22Duodenal stenosis (HP:0100867)2.63050624
23Abnormality of the astrocytes (HP:0100707)2.62849630
24Astrocytoma (HP:0009592)2.62849630
25Retrobulbar optic neuritis (HP:0100654)2.54083484
26Optic neuritis (HP:0100653)2.54083484
27Prostate neoplasm (HP:0100787)2.52672000
28Type I transferrin isoform profile (HP:0003642)2.49225665
29Reticulocytopenia (HP:0001896)2.48518552
30IgM deficiency (HP:0002850)2.44830226
31Myelodysplasia (HP:0002863)2.39759713
32Bone marrow hypocellularity (HP:0005528)2.36265190
33Increased nuchal translucency (HP:0010880)2.32730542
34Overlapping toe (HP:0001845)2.32545445
35IgG deficiency (HP:0004315)2.26705654
36Obstructive lung disease (HP:0006536)2.26065241
37Chronic obstructive pulmonary disease (HP:0006510)2.26065241
38Abnormality of the carotid arteries (HP:0005344)2.23371230
39Abnormality of the labia minora (HP:0012880)2.21734493
40Nephroblastoma (Wilms tumor) (HP:0002667)2.21246809
41Neoplasm of the adrenal cortex (HP:0100641)2.21000988
42Cafe-au-lait spot (HP:0000957)2.20726887
43Neoplasm of the colon (HP:0100273)2.20712325
44Abnormality of the duodenum (HP:0002246)2.20503539
45Recurrent abscess formation (HP:0002722)2.19536990
46Thyroid carcinoma (HP:0002890)2.18567086
47Neoplasm of striated muscle (HP:0009728)2.17717594
48Pancreatic fibrosis (HP:0100732)2.15392848
49Supernumerary spleens (HP:0009799)2.14869828
50Septo-optic dysplasia (HP:0100842)2.14223894
51Patellar aplasia (HP:0006443)2.11421060
52Triphalangeal thumb (HP:0001199)2.10659527
53Abnormality of the prostate (HP:0008775)2.09089446
54Agnosia (HP:0010524)2.06951044
55Embryonal neoplasm (HP:0002898)2.05641858
56Type 2 muscle fiber atrophy (HP:0003554)2.05180310
57Reduced antithrombin III activity (HP:0001976)2.04864252
58Aplasia/Hypoplasia of the sacrum (HP:0008517)2.01939177
59Embryonal renal neoplasm (HP:0011794)2.01606951
60Stomatitis (HP:0010280)2.01299827
61Lymphoma (HP:0002665)2.00852996
62Patchy hypopigmentation of hair (HP:0011365)1.99809832
63Stomach cancer (HP:0012126)1.99111852
64Abnormal delayed hypersensitivity skin test (HP:0002963)1.98576700
65Biliary tract neoplasm (HP:0100574)1.96504646
66Duplication of thumb phalanx (HP:0009942)1.95763975
67Premature graying of hair (HP:0002216)1.95758636
68Congenital stationary night blindness (HP:0007642)1.95722298
69Myositis (HP:0100614)1.94938704
70Absent thumb (HP:0009777)1.94405681
71Arteriovenous malformation (HP:0100026)1.92664957
72Asplenia (HP:0001746)1.91325339
73Aplasia/Hypoplasia of the patella (HP:0006498)1.91226913
74Abnormal biliary tract physiology (HP:0012439)1.90873478
75Bile duct proliferation (HP:0001408)1.90873478
76Aplastic anemia (HP:0001915)1.89656194
77Long clavicles (HP:0000890)1.89586866
78Encephalitis (HP:0002383)1.89428408
79Pancreatic cysts (HP:0001737)1.89219335
80Degeneration of anterior horn cells (HP:0002398)1.88531160
81Abnormality of the anterior horn cell (HP:0006802)1.88531160
82Absent radius (HP:0003974)1.88466167
83Microvesicular hepatic steatosis (HP:0001414)1.88388094
84Abnormality of the columella (HP:0009929)1.88096965
85Severe combined immunodeficiency (HP:0004430)1.87824500
86Abnormality of the septum pellucidum (HP:0007375)1.87429352
87Amaurosis fugax (HP:0100576)1.86277877
88High anterior hairline (HP:0009890)1.85582515
89Neoplasm of the small intestine (HP:0100833)1.85424632
90Ovarian neoplasm (HP:0100615)1.84396808
91Transitional cell carcinoma of the bladder (HP:0006740)1.83737610
92Breast hypoplasia (HP:0003187)1.82233896
93Gastrointestinal carcinoma (HP:0002672)1.82049621
94Malignant gastrointestinal tract tumors (HP:0006749)1.82049621
95Combined immunodeficiency (HP:0005387)1.82009780
96Sloping forehead (HP:0000340)1.81660853
97Abnormality of the pons (HP:0007361)1.81194546
98Bladder neoplasm (HP:0009725)1.80862196
99Bladder carcinoma (HP:0002862)1.80862196
100Abnormality of T cell number (HP:0011839)1.80753997
101True hermaphroditism (HP:0010459)1.80606948
102White forelock (HP:0002211)1.80455263
103T lymphocytopenia (HP:0005403)1.80328876
104Preaxial hand polydactyly (HP:0001177)1.80068933
105Neoplasm of the adrenal gland (HP:0100631)1.78882849
106Abnormal lung lobation (HP:0002101)1.78814150
107Absent septum pellucidum (HP:0001331)1.77992781
108Absent forearm bone (HP:0003953)1.77786684
109Aplasia involving forearm bones (HP:0009822)1.77786684
110Intestinal atresia (HP:0011100)1.76840890
111Osteomalacia (HP:0002749)1.76283696
112Pancytopenia (HP:0001876)1.75406381
113Abnormality of the metopic suture (HP:0005556)1.75035737
114Recurrent pneumonia (HP:0006532)1.74593050
115Dandy-Walker malformation (HP:0001305)1.74396935
116Parakeratosis (HP:0001036)1.74382805
117Bifid tongue (HP:0010297)1.73656217
118Hypoplasia of the pons (HP:0012110)1.72971191
119Abnormal hair whorl (HP:0010721)1.72891827
120Renal cortical cysts (HP:0000803)1.71633460
121Aplasia/Hypoplasia of the earlobes (HP:0009906)1.71430196
122IgA deficiency (HP:0002720)1.70592314
123Breast carcinoma (HP:0003002)1.70490599
124Prominent metopic ridge (HP:0005487)1.70474695
125Deep philtrum (HP:0002002)1.70457352
126Abnormality of T cells (HP:0002843)1.69591332
127Medulloblastoma (HP:0002885)1.69415803
128Absent rod-and cone-mediated responses on ERG (HP:0007688)1.69267196
129Increased IgM level (HP:0003496)1.68845556
130Abnormal protein glycosylation (HP:0012346)1.68461260
131Abnormal glycosylation (HP:0012345)1.68461260
132Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.68461260
133Abnormal protein N-linked glycosylation (HP:0012347)1.68461260
134Impaired vibration sensation in the lower limbs (HP:0002166)1.68172070
135Median cleft lip (HP:0000161)1.67485225
136Orchitis (HP:0100796)1.67309191
137Small hand (HP:0200055)1.67094863
138Astigmatism (HP:0000483)1.66419867
139Aplasia/Hypoplasia of the spleen (HP:0010451)1.65540506
1403-Methylglutaconic aciduria (HP:0003535)1.64679352
141Leiomyosarcoma (HP:0100243)1.64462228
142Uterine leiomyosarcoma (HP:0002891)1.64462228
143Oligohydramnios (HP:0001562)1.64442482
144Optic nerve coloboma (HP:0000588)1.64112290
145B lymphocytopenia (HP:0010976)1.64091325
146Abnormality of B cell number (HP:0010975)1.64091325
147Central scotoma (HP:0000603)1.63430484
148Recurrent bacterial skin infections (HP:0005406)1.63390204
149Chronic hepatic failure (HP:0100626)1.63111323
150Abnormality of the incisor (HP:0000676)1.62689187
151Uterine neoplasm (HP:0010784)1.62156752
152Leukopenia (HP:0001882)1.62105504
153Meningitis (HP:0001287)1.62026813
154Basal cell carcinoma (HP:0002671)1.59368155
155Aplasia/Hypoplasia of the sternum (HP:0006714)1.58308036
156Atrophy/Degeneration involving motor neurons (HP:0007373)1.58111725
157Neuroectodermal neoplasm (HP:0030061)1.57520291
158Neuroepithelial neoplasm (HP:0030063)1.57520291
159Nervous tissue neoplasm (HP:0030060)1.57520291
160Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.57289080
161Hepatoblastoma (HP:0002884)1.57143702
162Facial hemangioma (HP:0000329)1.56994302
163Drooling (HP:0002307)1.56657005
164Proximal placement of thumb (HP:0009623)1.56542949
165Carpal bone hypoplasia (HP:0001498)1.56529657
166Postnatal microcephaly (HP:0005484)1.56423644
167Curly hair (HP:0002212)1.55859378
168Prominent nose (HP:0000448)1.55023765
169Single umbilical artery (HP:0001195)1.54789983

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.46176129
2SRPK12.78644218
3TRIM282.74902647
4NEK12.51138560
5ZAK2.46809875
6IRAK42.45568657
7TXK2.43963466
8MAP3K142.43813829
9PLK42.35781893
10BUB12.31442295
11TNIK2.19065639
12MKNK12.16185062
13NUAK12.03834096
14EIF2AK21.98739198
15CDC71.97788484
16MKNK21.90909987
17CASK1.87316286
18VRK11.81752366
19YES11.77058905
20PRPF4B1.74701067
21IRAK31.67335055
22MAP4K21.66474505
23WNK31.64170959
24TAF11.60486681
25BMPR1B1.60389187
26EIF2AK11.57942704
27SIK31.49952062
28EIF2AK31.47915847
29TLK11.43911368
30BRD41.37119635
31PNCK1.36680540
32BRSK21.31482186
33CLK11.28424051
34FRK1.25656636
35MAP3K41.25169566
36ATR1.22887457
37CDK31.20156969
38MAP3K101.19918485
39NEK61.19639820
40PLK31.18929997
41JAK31.17615152
42WEE11.15719823
43IKBKE1.13906977
44PLK21.12551824
45TEC1.11359847
46CHEK21.09404752
47TSSK61.09197220
48ACVR1B1.08604268
49ADRBK21.08466589
50PLK11.07039114
51TTK1.02555738
52MUSK1.02042010
53RPS6KA51.01725872
54PBK1.01635959
55MAP2K71.01234406
56CDK81.00432289
57NME20.99401424
58BMPR20.98218777
59IKBKB0.98059876
60MAP4K10.95877402
61BLK0.93820761
62SCYL20.93096311
63ERBB30.90270141
64BCR0.89767182
65NLK0.89228372
66CDK190.85656497
67STK30.85406798
68CSNK1G20.85064965
69MAP3K120.84810719
70CHUK0.81858686
71AKT30.81548876
72TYK20.78800675
73MAPK130.78300490
74BTK0.76977085
75MELK0.76205885
76IRAK10.75955738
77DYRK30.74161110
78BRSK10.73734343
79CDK60.72291222
80DYRK20.72155399
81CDK70.71782927
82AURKB0.71513781
83PIM10.69492535
84CCNB10.67736874
85STK40.67621238
86LYN0.65995673
87IRAK20.65728235
88PASK0.64197640
89ATM0.62381124
90KIT0.62061444
91STK100.59883345
92GRK10.59638024
93LCK0.58404748
94SYK0.56099573
95CHEK10.55895484
96CDK120.55223262
97LATS10.54716280
98TRPM70.54687800
99PKN10.54042363
100MAP3K50.53561304
101MST40.53191595
102NEK20.52470610
103CDK20.52314702
104CSNK1A1L0.51103549
105FGFR10.47856876
106TNK20.47156617
107RPS6KA40.47092451
108CSNK1G30.46609031
109MARK30.46056291
110RAF10.45266574
111EPHA30.44160201
112STK38L0.44037198
113ZAP700.43676035
114MAP3K90.43572914
115GRK70.43466913
116CDK90.43464249
117MAP3K130.43215770
118MINK10.42584067
119NEK90.42234634
120CDK10.39984664
121KSR10.39669003
122TGFBR10.39227027
123TAOK20.39102791
124PRKCQ0.39094872
125SGK20.38810583
126MAPKAPK50.38055146
127BRAF0.38045988
128CSNK2A10.37744997
129PRKDC0.36742730
130STK240.36671894
131CSNK1G10.36600110
132CSNK2A20.35135765
133EGFR0.31027930
134CSNK1E0.30831349
135STK390.30528465
136CSNK1D0.30279302
137CDK40.27783836
138AURKA0.26411483

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.27390047
2Mismatch repair_Homo sapiens_hsa034303.13470218
3Fanconi anemia pathway_Homo sapiens_hsa034603.10985588
4Homologous recombination_Homo sapiens_hsa034402.91824452
5RNA polymerase_Homo sapiens_hsa030202.76576281
6Non-homologous end-joining_Homo sapiens_hsa034502.46192477
7Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.29194000
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.20069777
9Nucleotide excision repair_Homo sapiens_hsa034202.18855578
10Spliceosome_Homo sapiens_hsa030402.15717821
11Base excision repair_Homo sapiens_hsa034102.13448881
12Basal transcription factors_Homo sapiens_hsa030222.00330416
13Pyrimidine metabolism_Homo sapiens_hsa002401.84523902
14Proteasome_Homo sapiens_hsa030501.82230395
15Allograft rejection_Homo sapiens_hsa053301.79819774
16Cell cycle_Homo sapiens_hsa041101.78792880
17Primary immunodeficiency_Homo sapiens_hsa053401.64352257
18Autoimmune thyroid disease_Homo sapiens_hsa053201.64288037
19NF-kappa B signaling pathway_Homo sapiens_hsa040641.61894701
20RNA degradation_Homo sapiens_hsa030181.59342696
21Propanoate metabolism_Homo sapiens_hsa006401.56466909
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.52107042
23Ribosome_Homo sapiens_hsa030101.49477985
24Graft-versus-host disease_Homo sapiens_hsa053321.47934358
25Measles_Homo sapiens_hsa051621.46939118
26RNA transport_Homo sapiens_hsa030131.46878561
27Protein export_Homo sapiens_hsa030601.45709167
28Oocyte meiosis_Homo sapiens_hsa041141.44834571
29Selenocompound metabolism_Homo sapiens_hsa004501.39617632
30Herpes simplex infection_Homo sapiens_hsa051681.36265112
31Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.31005777
32Purine metabolism_Homo sapiens_hsa002301.30628451
33Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.30424381
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.30171748
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.22376480
36p53 signaling pathway_Homo sapiens_hsa041151.22125351
37Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.21353631
38Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.15263198
39Asthma_Homo sapiens_hsa053101.12843049
40RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.10312798
41NOD-like receptor signaling pathway_Homo sapiens_hsa046211.10032153
42Hematopoietic cell lineage_Homo sapiens_hsa046401.04432658
43Phototransduction_Homo sapiens_hsa047441.02920550
44* mRNA surveillance pathway_Homo sapiens_hsa030150.99730324
45Epstein-Barr virus infection_Homo sapiens_hsa051690.99685753
46Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.95675033
47Sphingolipid metabolism_Homo sapiens_hsa006000.95642711
48SNARE interactions in vesicular transport_Homo sapiens_hsa041300.94515153
49Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.94400436
50Systemic lupus erythematosus_Homo sapiens_hsa053220.91296490
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.89994822
52Colorectal cancer_Homo sapiens_hsa052100.88069268
53One carbon pool by folate_Homo sapiens_hsa006700.86489489
54Leishmaniasis_Homo sapiens_hsa051400.84404957
55Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.83075530
56Antigen processing and presentation_Homo sapiens_hsa046120.81871979
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.81415241
58Fatty acid elongation_Homo sapiens_hsa000620.81253078
59Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.80980882
60Pyruvate metabolism_Homo sapiens_hsa006200.80155647
61Jak-STAT signaling pathway_Homo sapiens_hsa046300.79293572
62Lysine degradation_Homo sapiens_hsa003100.79065635
63Type I diabetes mellitus_Homo sapiens_hsa049400.78532505
64Arachidonic acid metabolism_Homo sapiens_hsa005900.78373186
65Influenza A_Homo sapiens_hsa051640.76240766
66Transcriptional misregulation in cancer_Homo sapiens_hsa052020.75396730
67Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.75329527
68Ether lipid metabolism_Homo sapiens_hsa005650.73449436
69Toll-like receptor signaling pathway_Homo sapiens_hsa046200.72614074
70T cell receptor signaling pathway_Homo sapiens_hsa046600.71967434
71Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.67145110
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.66708565
73Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.65372778
74Regulation of autophagy_Homo sapiens_hsa041400.63882847
75Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63193742
76Viral carcinogenesis_Homo sapiens_hsa052030.62724713
77Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61581187
78TGF-beta signaling pathway_Homo sapiens_hsa043500.60286969
79Nicotine addiction_Homo sapiens_hsa050330.60071725
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.58685780
81Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58035475
82Thyroid cancer_Homo sapiens_hsa052160.57925641
83Biosynthesis of amino acids_Homo sapiens_hsa012300.57578744
84Hepatitis B_Homo sapiens_hsa051610.57169142
85Legionellosis_Homo sapiens_hsa051340.56788701
86Chemokine signaling pathway_Homo sapiens_hsa040620.56438798
87Rheumatoid arthritis_Homo sapiens_hsa053230.55779957
88Malaria_Homo sapiens_hsa051440.54774504
89Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.54557485
90Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.53073116
91Alcoholism_Homo sapiens_hsa050340.52540549
92Steroid biosynthesis_Homo sapiens_hsa001000.52028180
93Apoptosis_Homo sapiens_hsa042100.51970152
94N-Glycan biosynthesis_Homo sapiens_hsa005100.51312786
95Vitamin B6 metabolism_Homo sapiens_hsa007500.49357556
96HTLV-I infection_Homo sapiens_hsa051660.49114351
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.46412984
98Adherens junction_Homo sapiens_hsa045200.45665720
99TNF signaling pathway_Homo sapiens_hsa046680.45561201
100Pertussis_Homo sapiens_hsa051330.44008238
101Wnt signaling pathway_Homo sapiens_hsa043100.43695250
102Shigellosis_Homo sapiens_hsa051310.43633756
103Osteoclast differentiation_Homo sapiens_hsa043800.43470647
104B cell receptor signaling pathway_Homo sapiens_hsa046620.42085714
105Serotonergic synapse_Homo sapiens_hsa047260.41478655
106Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.40876535
107Hippo signaling pathway_Homo sapiens_hsa043900.40351481
108Linoleic acid metabolism_Homo sapiens_hsa005910.39471053
109Carbon metabolism_Homo sapiens_hsa012000.39358436
110Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.38846502
111MicroRNAs in cancer_Homo sapiens_hsa052060.38679415
112Viral myocarditis_Homo sapiens_hsa054160.36683684
113Hepatitis C_Homo sapiens_hsa051600.36380645
114Non-small cell lung cancer_Homo sapiens_hsa052230.36284743
115Other glycan degradation_Homo sapiens_hsa005110.35800024
116Small cell lung cancer_Homo sapiens_hsa052220.35273623
117Fatty acid metabolism_Homo sapiens_hsa012120.34896844
118African trypanosomiasis_Homo sapiens_hsa051430.34845297
119Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34414142
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.34108455
121Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.33433220
122Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.32164385
123Taste transduction_Homo sapiens_hsa047420.31823327
124Chronic myeloid leukemia_Homo sapiens_hsa052200.31250513
125Toxoplasmosis_Homo sapiens_hsa051450.31073692
126Tuberculosis_Homo sapiens_hsa051520.30846892
127Pancreatic cancer_Homo sapiens_hsa052120.30662702
128Morphine addiction_Homo sapiens_hsa050320.29452625
129Hedgehog signaling pathway_Homo sapiens_hsa043400.29450811
130Inositol phosphate metabolism_Homo sapiens_hsa005620.29415715
131Butanoate metabolism_Homo sapiens_hsa006500.27340166
132Phagosome_Homo sapiens_hsa041450.27032530
133alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26322669
1342-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.26191058
135Melanoma_Homo sapiens_hsa052180.25359476
136Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.25143360
137Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.24741638
138FoxO signaling pathway_Homo sapiens_hsa040680.24628372
139Prostate cancer_Homo sapiens_hsa052150.23898483
140Salmonella infection_Homo sapiens_hsa051320.22599992
141Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.18019429
142Central carbon metabolism in cancer_Homo sapiens_hsa052300.17695960
143Circadian rhythm_Homo sapiens_hsa047100.17154164
144Endometrial cancer_Homo sapiens_hsa052130.16837463
145Phosphatidylinositol signaling system_Homo sapiens_hsa040700.14742791
146Pathways in cancer_Homo sapiens_hsa052000.11237178
147Metabolic pathways_Homo sapiens_hsa011000.09191693
148Folate biosynthesis_Homo sapiens_hsa007900.08042551
149Basal cell carcinoma_Homo sapiens_hsa052170.07161861
150Glioma_Homo sapiens_hsa052140.05803734
151Thyroid hormone signaling pathway_Homo sapiens_hsa049190.05599782

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