RNMT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)5.03158564
2purine nucleobase biosynthetic process (GO:0009113)4.28408452
3nucleobase biosynthetic process (GO:0046112)4.22250802
4regulation of DNA endoreduplication (GO:0032875)4.16432429
5histone H3-K9 demethylation (GO:0033169)4.11458162
6regulation of histone H3-K9 methylation (GO:0051570)4.07901630
7maturation of 5.8S rRNA (GO:0000460)4.04039345
8mitotic metaphase plate congression (GO:0007080)3.94584871
9CENP-A containing nucleosome assembly (GO:0034080)3.80107504
10chromatin remodeling at centromere (GO:0031055)3.71510528
11DNA replication initiation (GO:0006270)3.70785360
12resolution of meiotic recombination intermediates (GO:0000712)3.65843068
13ribosome assembly (GO:0042255)3.65739416
14ribosome biogenesis (GO:0042254)3.65253916
15regulation of RNA export from nucleus (GO:0046831)3.64997721
16regulation of chromatin silencing (GO:0031935)3.62312815
17DNA synthesis involved in DNA repair (GO:0000731)3.61029674
18sister chromatid cohesion (GO:0007062)3.60403099
19proteasome assembly (GO:0043248)3.59063672
20synapsis (GO:0007129)3.58756071
21DNA strand elongation involved in DNA replication (GO:0006271)3.58558190
22DNA replication checkpoint (GO:0000076)3.55633417
23centriole replication (GO:0007099)3.54108927
24telomere maintenance via semi-conservative replication (GO:0032201)3.51795401
25transcription elongation from RNA polymerase III promoter (GO:0006385)3.50717433
26termination of RNA polymerase III transcription (GO:0006386)3.50717433
27maturation of SSU-rRNA (GO:0030490)3.48155226
28DNA strand elongation (GO:0022616)3.45851418
29cullin deneddylation (GO:0010388)3.41713018
30transcription elongation from RNA polymerase I promoter (GO:0006362)3.41483897
31negative regulation of DNA-dependent DNA replication (GO:2000104)3.40766473
32IMP biosynthetic process (GO:0006188)3.38913148
33telomere maintenance via recombination (GO:0000722)3.38846255
34metaphase plate congression (GO:0051310)3.37041246
35DNA replication-independent nucleosome organization (GO:0034724)3.36456807
36DNA replication-independent nucleosome assembly (GO:0006336)3.36456807
37nuclear pore organization (GO:0006999)3.34841112
38attachment of spindle microtubules to kinetochore (GO:0008608)3.34597841
39pre-miRNA processing (GO:0031054)3.33961785
40sister chromatid segregation (GO:0000819)3.32633292
41termination of RNA polymerase I transcription (GO:0006363)3.32002157
42formation of translation preinitiation complex (GO:0001731)3.30580001
43ribosomal small subunit assembly (GO:0000028)3.30483877
44viral mRNA export from host cell nucleus (GO:0046784)3.27830346
45protein localization to kinetochore (GO:0034501)3.27063532
46mitotic recombination (GO:0006312)3.26730380
47replication fork processing (GO:0031297)3.26543726
48kinetochore organization (GO:0051383)3.26491332
49* 7-methylguanosine mRNA capping (GO:0006370)3.26169985
50protein deneddylation (GO:0000338)3.25563533
51* 7-methylguanosine RNA capping (GO:0009452)3.23688147
52* RNA capping (GO:0036260)3.23688147
53DNA topological change (GO:0006265)3.22640286
54non-recombinational repair (GO:0000726)3.20971158
55double-strand break repair via nonhomologous end joining (GO:0006303)3.20971158
56histone H3-K36 demethylation (GO:0070544)3.20010446
57histone exchange (GO:0043486)3.19074322
58mitotic chromosome condensation (GO:0007076)3.18364355
59spliceosomal snRNP assembly (GO:0000387)3.15988145
60anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.15435861
61transcription-coupled nucleotide-excision repair (GO:0006283)3.14975547
62ribonucleoprotein complex biogenesis (GO:0022613)3.13823815
63regulation of nuclear cell cycle DNA replication (GO:0033262)3.12897019
64regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.12569769
65rRNA modification (GO:0000154)3.11701485
66positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.11483872
67negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.11263004
68establishment of chromosome localization (GO:0051303)3.09288362
69pore complex assembly (GO:0046931)3.08961312
70DNA unwinding involved in DNA replication (GO:0006268)3.07771970
71positive regulation of mitotic sister chromatid separation (GO:1901970)3.06907836
72positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.06907836
73positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.06907836
74rRNA processing (GO:0006364)3.06509575
75transcription from RNA polymerase I promoter (GO:0006360)3.05458610
76DNA replication-dependent nucleosome organization (GO:0034723)3.04655085
77DNA replication-dependent nucleosome assembly (GO:0006335)3.04655085
78pseudouridine synthesis (GO:0001522)3.03629820
79histone H2A acetylation (GO:0043968)3.03330731
80kinetochore assembly (GO:0051382)3.03088086
81telomere maintenance via telomere lengthening (GO:0010833)3.01864713
82IMP metabolic process (GO:0046040)3.01419995
83negative regulation of DNA repair (GO:0045738)3.00243001
84DNA double-strand break processing (GO:0000729)2.99531943
85ribosomal large subunit biogenesis (GO:0042273)2.99360613
86mitotic nuclear envelope disassembly (GO:0007077)2.98857161
87regulation of helicase activity (GO:0051095)2.98085943
88telomere maintenance via telomerase (GO:0007004)2.97877945
89positive regulation of histone methylation (GO:0031062)2.97852086
90rRNA metabolic process (GO:0016072)2.97337531
91establishment of integrated proviral latency (GO:0075713)2.97192445
92nucleotide-excision repair, DNA gap filling (GO:0006297)2.97002162
93regulation of meiosis I (GO:0060631)2.95974164
94somatic diversification of immune receptors via somatic mutation (GO:0002566)2.95401908
95somatic hypermutation of immunoglobulin genes (GO:0016446)2.95401908
96protein K6-linked ubiquitination (GO:0085020)2.93722372
97transcription initiation from RNA polymerase I promoter (GO:0006361)2.93354742
98mismatch repair (GO:0006298)2.91136231
99regulation of centriole replication (GO:0046599)2.91100924
100monoubiquitinated protein deubiquitination (GO:0035520)2.90545015
101negative regulation of DNA recombination (GO:0045910)2.89956305
102spliceosomal complex assembly (GO:0000245)2.89787803
103chromosome organization involved in meiosis (GO:0070192)2.89615910
104spindle checkpoint (GO:0031577)2.89572303
105cell cycle G1/S phase transition (GO:0044843)2.89264745
106G1/S transition of mitotic cell cycle (GO:0000082)2.89264745
107DNA-templated transcription, termination (GO:0006353)2.88529562
108histone lysine demethylation (GO:0070076)2.87221240
109nuclear pore complex assembly (GO:0051292)2.86829280
110negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.82800281
111negative regulation of sister chromatid segregation (GO:0033046)2.82800281
112negative regulation of mitotic sister chromatid separation (GO:2000816)2.82800281
113negative regulation of mitotic sister chromatid segregation (GO:0033048)2.82800281
114maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.82057688
115histone demethylation (GO:0016577)2.82053491
116mitotic sister chromatid segregation (GO:0000070)2.82022956
117nuclear envelope disassembly (GO:0051081)2.81383559
118membrane disassembly (GO:0030397)2.81383559
119DNA deamination (GO:0045006)2.81326065
120negative regulation of histone methylation (GO:0031061)2.80924641
121spindle assembly checkpoint (GO:0071173)2.80294209
122negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.80271265
123negative regulation of ligase activity (GO:0051352)2.80271265
124establishment of protein localization to mitochondrial membrane (GO:0090151)2.80238667
125negative regulation of chromosome segregation (GO:0051985)2.79079529
126ribonucleoprotein complex disassembly (GO:0032988)2.78983921
127peptidyl-arginine omega-N-methylation (GO:0035247)2.78959238
128postreplication repair (GO:0006301)2.78822139
129negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.78711135
130negative regulation of translation, ncRNA-mediated (GO:0040033)2.78711135
131regulation of translation, ncRNA-mediated (GO:0045974)2.78711135
132regulation of mitotic metaphase/anaphase transition (GO:0030071)2.78445246
133positive regulation of chromosome segregation (GO:0051984)2.78398202
134protein localization to chromosome (GO:0034502)2.78179152
135negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.76831357
136mitotic spindle assembly checkpoint (GO:0007094)2.76772768
137regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.76463545
138positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.75707730
139mitotic spindle checkpoint (GO:0071174)2.75624976
140regulation of sister chromatid segregation (GO:0033045)2.75545051
141regulation of mitotic sister chromatid separation (GO:0010965)2.75545051
142regulation of mitotic sister chromatid segregation (GO:0033047)2.75545051
143protein demethylation (GO:0006482)2.74620330
144protein dealkylation (GO:0008214)2.74620330
145regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.73931873
146meiotic chromosome segregation (GO:0045132)2.72033195
147ER overload response (GO:0006983)2.70387990
148genitalia morphogenesis (GO:0035112)2.69056525
149mitotic G2/M transition checkpoint (GO:0044818)2.68696300
150acrosome assembly (GO:0001675)2.66682421
151regulation of nucleobase-containing compound transport (GO:0032239)2.66421438
152regulation of chromosome segregation (GO:0051983)2.65459065
153regulation of sister chromatid cohesion (GO:0007063)2.65261428
154regulation of gene silencing (GO:0060968)2.64916253
155regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.63011742
156DNA ligation (GO:0006266)2.60976848
157heterochromatin organization (GO:0070828)2.59896551
158regulation of transcription from RNA polymerase I promoter (GO:0006356)2.59233065
159regulation of histone methylation (GO:0031060)2.58912971
160negative regulation of RNA splicing (GO:0033119)2.57970332
161protein localization to chromosome, centromeric region (GO:0071459)2.54776281
162positive regulation of histone H3-K4 methylation (GO:0051571)2.53795656

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.21716382
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.12678348
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.84062222
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.71231278
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.41061070
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.28908808
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.19570671
8* ETS1_20019798_ChIP-Seq_JURKAT_Human2.95463632
9HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.93974307
10* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.85856138
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.84457378
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.77921457
13RBPJ_22232070_ChIP-Seq_NCS_Mouse2.77448605
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.73898279
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.62595296
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.58950549
17EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.57778228
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.52618955
19VDR_23849224_ChIP-Seq_CD4+_Human2.46729711
20* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.42088541
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.40279380
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.36173836
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.33360752
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.28216012
25YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.26553117
26ELK1_19687146_ChIP-ChIP_HELA_Human2.23793517
27NELFA_20434984_ChIP-Seq_ESCs_Mouse2.23182846
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.22650455
29* THAP11_20581084_ChIP-Seq_MESCs_Mouse2.18983432
30FOXP3_21729870_ChIP-Seq_TREG_Human2.14933967
31XRN2_22483619_ChIP-Seq_HELA_Human2.08265814
32MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.07280411
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.04114865
34TAF15_26573619_Chip-Seq_HEK293_Human2.03307046
35* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.94596276
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.90537990
37* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.90195879
38* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.89967596
39E2F1_21310950_ChIP-Seq_MCF-7_Human1.89214665
40DCP1A_22483619_ChIP-Seq_HELA_Human1.87959915
41SALL1_21062744_ChIP-ChIP_HESCs_Human1.85506291
42GABP_19822575_ChIP-Seq_HepG2_Human1.82497676
43TTF2_22483619_ChIP-Seq_HELA_Human1.81574255
44CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.80845090
45ELF1_17652178_ChIP-ChIP_JURKAT_Human1.79748458
46YY1_21170310_ChIP-Seq_MESCs_Mouse1.72910509
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.66258899
48* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.65780732
49HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.65668550
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.63721795
51NANOG_18555785_ChIP-Seq_MESCs_Mouse1.62054412
52ZNF274_21170338_ChIP-Seq_K562_Hela1.58306924
53ZFP57_27257070_Chip-Seq_ESCs_Mouse1.55324539
54TP63_19390658_ChIP-ChIP_HaCaT_Human1.52789799
55PADI4_21655091_ChIP-ChIP_MCF-7_Human1.52544926
56P300_19829295_ChIP-Seq_ESCs_Human1.50633018
57WT1_19549856_ChIP-ChIP_CCG9911_Human1.46135891
58GBX2_23144817_ChIP-Seq_PC3_Human1.45464965
59* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.42095471
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.40182048
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.37818428
62CIITA_25753668_ChIP-Seq_RAJI_Human1.37716646
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.37287298
64EGR1_19374776_ChIP-ChIP_THP-1_Human1.37029747
65ZFX_18555785_ChIP-Seq_MESCs_Mouse1.35185379
66AR_21909140_ChIP-Seq_LNCAP_Human1.31469687
67FUS_26573619_Chip-Seq_HEK293_Human1.30338946
68CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.28412499
69MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.28257701
70IGF1R_20145208_ChIP-Seq_DFB_Human1.27819180
71PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.25190550
72KDM5A_27292631_Chip-Seq_BREAST_Human1.24985875
73EWS_26573619_Chip-Seq_HEK293_Human1.23973806
74MYC_18940864_ChIP-ChIP_HL60_Human1.22724402
75HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.22402152
76CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21567101
77VDR_22108803_ChIP-Seq_LS180_Human1.20694272
78CTBP1_25329375_ChIP-Seq_LNCAP_Human1.17804312
79AR_21572438_ChIP-Seq_LNCaP_Human1.15701081
80AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.15550277
81SOX2_18555785_ChIP-Seq_MESCs_Mouse1.15249159
82RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.14846915
83SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14663035
84ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.13429239
85OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12682899
86GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.12090464
87STAT3_23295773_ChIP-Seq_U87_Human1.11019675
88TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.10959339
89* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.08343800
90GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08073646
91* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.07590029
92TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.07250312
93CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07192631
94SOX9_26525672_Chip-Seq_HEART_Mouse1.05978954
95SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.05795655
96FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.04524117
97* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.03865438
98SMAD4_21799915_ChIP-Seq_A2780_Human1.03120754
99TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.02355727
100NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.01551583
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01455980
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.01455980
103* TCF4_23295773_ChIP-Seq_U87_Human1.00883722
104FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.00632155
105TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98998277
106E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97977113
107CBP_20019798_ChIP-Seq_JUKART_Human0.97729253
108IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97729253
109SMAD3_21741376_ChIP-Seq_EPCs_Human0.96764715
110NANOG_18555785_Chip-Seq_ESCs_Mouse0.96552870
111ER_23166858_ChIP-Seq_MCF-7_Human0.95788457
112CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.95061602
113SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.94767010
114TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.93998565
115* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.93760606
116RNF2_27304074_Chip-Seq_NSC_Mouse0.93655270
117E2F1_18555785_Chip-Seq_ESCs_Mouse0.93325064
118CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.91744274
119POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91565350
120TFEB_21752829_ChIP-Seq_HELA_Human0.91348808
121EZH2_27294783_Chip-Seq_NPCs_Mouse0.90095725
122SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.89012628
123* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88795146
124* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.88340691
125POU5F1_16153702_ChIP-ChIP_HESCs_Human0.88278710
126SOX2_16153702_ChIP-ChIP_HESCs_Human0.87401640
127ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.86925590
128ELK1_22589737_ChIP-Seq_MCF10A_Human0.86509755
129IRF1_19129219_ChIP-ChIP_H3396_Human0.84757061
130FLI1_27457419_Chip-Seq_LIVER_Mouse0.84604639
131KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.84369972
132GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83054290
133BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.81955214
134PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.81166063
135CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.77780590
136CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.77221492
137SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.76720349
138NANOG_21062744_ChIP-ChIP_HESCs_Human0.75128824
139NANOG_16153702_ChIP-ChIP_HESCs_Human0.74592487
140* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.73877803
141* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.72539103
142PCGF2_27294783_Chip-Seq_ESCs_Mouse0.67405806
143POU3F2_20337985_ChIP-ChIP_501MEL_Human0.67180122

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.35106471
2MP0010094_abnormal_chromosome_stability4.10532885
3MP0008057_abnormal_DNA_replication3.60955773
4MP0003111_abnormal_nucleus_morphology3.58783465
5MP0004957_abnormal_blastocyst_morpholog3.48147392
6MP0008058_abnormal_DNA_repair3.32223111
7MP0003077_abnormal_cell_cycle3.30425497
8MP0008877_abnormal_DNA_methylation3.13443852
9MP0003123_paternal_imprinting3.11919930
10MP0008007_abnormal_cellular_replicative2.54592199
11MP0003787_abnormal_imprinting2.36077951
12MP0006292_abnormal_olfactory_placode2.33547336
13MP0003121_genomic_imprinting2.32057337
14MP0008932_abnormal_embryonic_tissue2.25807247
15MP0001188_hyperpigmentation2.22560004
16MP0003880_abnormal_central_pattern2.02044037
17MP0003786_premature_aging1.92061451
18MP0002396_abnormal_hematopoietic_system1.84832602
19MP0003718_maternal_effect1.73200625
20MP0000350_abnormal_cell_proliferation1.70555940
21MP0002822_catalepsy1.69396295
22MP0008995_early_reproductive_senescence1.67548947
23MP0001730_embryonic_growth_arrest1.63790946
24MP0003890_abnormal_embryonic-extraembry1.59784678
25MP0001986_abnormal_taste_sensitivity1.58294578
26MP0003941_abnormal_skin_development1.56560778
27MP0004859_abnormal_synaptic_plasticity1.56085043
28MP0003136_yellow_coat_color1.54724644
29MP0003950_abnormal_plasma_membrane1.49419779
30MP0003315_abnormal_perineum_morphology1.49366354
31MP0001984_abnormal_olfaction1.48424740
32MP0003937_abnormal_limbs/digits/tail_de1.42862105
33MP0010307_abnormal_tumor_latency1.40609959
34MP0009703_decreased_birth_body1.37988711
35MP0001529_abnormal_vocalization1.34867467
36MP0001286_abnormal_eye_development1.31411639
37MP0001697_abnormal_embryo_size1.28907535
38MP0001968_abnormal_touch/_nociception1.28170675
39MP0000015_abnormal_ear_pigmentation1.25871878
40MP0000569_abnormal_digit_pigmentation1.25343059
41MP0009672_abnormal_birth_weight1.22782841
42MP0003635_abnormal_synaptic_transmissio1.20535375
43MP0004808_abnormal_hematopoietic_stem1.19244464
44MP0002210_abnormal_sex_determination1.17867686
45MP0003122_maternal_imprinting1.17542368
46MP0002102_abnormal_ear_morphology1.17102707
47MP0002736_abnormal_nociception_after1.16946384
48MP0001672_abnormal_embryogenesis/_devel1.15240254
49MP0005380_embryogenesis_phenotype1.15240254
50MP0002160_abnormal_reproductive_system1.14141515
51MP0002254_reproductive_system_inflammat1.12793618
52MP0009046_muscle_twitch1.11248415
53MP0000313_abnormal_cell_death1.09911926
54MP0009745_abnormal_behavioral_response1.05828571
55MP0002638_abnormal_pupillary_reflex1.05766057
56MP0002095_abnormal_skin_pigmentation1.05251256
57MP0002080_prenatal_lethality1.05239530
58MP0003385_abnormal_body_wall1.05137016
59MP0002233_abnormal_nose_morphology1.03162396
60MP0005409_darkened_coat_color1.02232424
61MP0002085_abnormal_embryonic_tissue1.00674520
62MP0001905_abnormal_dopamine_level1.00139830
63MP0001177_atelectasis0.99462745
64MP0002084_abnormal_developmental_patter0.99092140
65MP0000490_abnormal_crypts_of0.98965761
66MP0002734_abnormal_mechanical_nocicepti0.98622814
67MP0002063_abnormal_learning/memory/cond0.98416676
68MP0003984_embryonic_growth_retardation0.98353044
69MP0001145_abnormal_male_reproductive0.98038288
70MP0002572_abnormal_emotion/affect_behav0.96852515
71MP0004133_heterotaxia0.96573069
72MP0002088_abnormal_embryonic_growth/wei0.95320836
73MP0002751_abnormal_autonomic_nervous0.93435414
74MP0004145_abnormal_muscle_electrophysio0.92459994
75MP0009697_abnormal_copulation0.91711570
76MP0004885_abnormal_endolymph0.91641242
77MP0002697_abnormal_eye_size0.91611043
78MP0005389_reproductive_system_phenotype0.91504135
79MP0003119_abnormal_digestive_system0.91434218
80MP0003943_abnormal_hepatobiliary_system0.90963129
81MP0000653_abnormal_sex_gland0.90640556
82MP0000647_abnormal_sebaceous_gland0.89934560
83MP0000427_abnormal_hair_cycle0.88913875
84MP0004270_analgesia0.88766550
85MP0002938_white_spotting0.88194827
86MP0002009_preneoplasia0.87268384
87MP0005499_abnormal_olfactory_system0.87093346
88MP0005394_taste/olfaction_phenotype0.87093346
89MP0001929_abnormal_gametogenesis0.86967704
90MP0003755_abnormal_palate_morphology0.85807662
91MP0002735_abnormal_chemical_nociception0.85054593
92MP0003935_abnormal_craniofacial_develop0.83762393
93MP0006276_abnormal_autonomic_nervous0.83030415
94MP0001119_abnormal_female_reproductive0.82740887
95MP0000372_irregular_coat_pigmentation0.81381530
96MP0002163_abnormal_gland_morphology0.81275789
97MP0003567_abnormal_fetal_cardiomyocyte0.81156852
98MP0002019_abnormal_tumor_incidence0.80934937
99MP0002152_abnormal_brain_morphology0.80902982
100MP0003221_abnormal_cardiomyocyte_apopto0.79683819
101MP0002067_abnormal_sensory_capabilities0.78854781
102MP0000358_abnormal_cell_content/0.78460743
103MP0000955_abnormal_spinal_cord0.78427515
104MP0001293_anophthalmia0.78381473
105MP0009379_abnormal_foot_pigmentation0.78138606
106MP0002086_abnormal_extraembryonic_tissu0.78136118
107MP0002064_seizures0.78091337
108MP0006035_abnormal_mitochondrial_morpho0.77671975
109MP0002184_abnormal_innervation0.77138005
110MP0004811_abnormal_neuron_physiology0.76876971
111MP0005423_abnormal_somatic_nervous0.76460993
112MP0002272_abnormal_nervous_system0.75889009
113MP0005174_abnormal_tail_pigmentation0.75825229
114MP0002081_perinatal_lethality0.75714248
115MP0001919_abnormal_reproductive_system0.75707034
116MP0004924_abnormal_behavior0.75530748
117MP0005386_behavior/neurological_phenoty0.75530748
118MP0004142_abnormal_muscle_tone0.75068653
119MP0003861_abnormal_nervous_system0.74523433
120MP0002234_abnormal_pharynx_morphology0.74184183
121MP0004197_abnormal_fetal_growth/weight/0.73749726
122MP0005384_cellular_phenotype0.73093867
123MP0010352_gastrointestinal_tract_polyps0.73088548
124MP0000516_abnormal_urinary_system0.72373435
125MP0005367_renal/urinary_system_phenotyp0.72373435
126MP0005646_abnormal_pituitary_gland0.72176175
127MP0000631_abnormal_neuroendocrine_gland0.71899825
128MP0001299_abnormal_eye_distance/0.71608862
129MP0002092_abnormal_eye_morphology0.67893262
130MP0005075_abnormal_melanosome_morpholog0.67077123
131MP0000703_abnormal_thymus_morphology0.66153797
132MP0001486_abnormal_startle_reflex0.65709096
133MP0001440_abnormal_grooming_behavior0.64775782
134MP0001186_pigmentation_phenotype0.64522409
135MP0000778_abnormal_nervous_system0.62501344
136MP0003698_abnormal_male_reproductive0.61911455

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.48067146
2Chromsome breakage (HP:0040012)3.84038710
3Abnormality of the labia minora (HP:0012880)3.70251050
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.66595578
5Breast hypoplasia (HP:0003187)3.23902533
6Aplastic anemia (HP:0001915)3.13132220
7Medulloblastoma (HP:0002885)3.04526936
8Patellar aplasia (HP:0006443)2.99500039
9Abnormality of chromosome stability (HP:0003220)2.95967399
10Agnosia (HP:0010524)2.87730733
11Aplasia/Hypoplasia of the patella (HP:0006498)2.81573864
12Meckel diverticulum (HP:0002245)2.79291640
13Abnormality of the preputium (HP:0100587)2.78861086
14Supernumerary spleens (HP:0009799)2.78575948
15Papillary thyroid carcinoma (HP:0002895)2.74155787
16Cerebral hypomyelination (HP:0006808)2.72422939
17Carpal bone hypoplasia (HP:0001498)2.65926447
18Oligodactyly (hands) (HP:0001180)2.63630872
19Degeneration of anterior horn cells (HP:0002398)2.63321351
20Abnormality of the anterior horn cell (HP:0006802)2.63321351
21Abnormality of the ileum (HP:0001549)2.62383116
22Aplasia/Hypoplasia of the uvula (HP:0010293)2.55691875
23Impulsivity (HP:0100710)2.54026844
24Myelodysplasia (HP:0002863)2.52849945
25Broad alveolar ridges (HP:0000187)2.49880490
26Overlapping toe (HP:0001845)2.45362995
27Rough bone trabeculation (HP:0100670)2.39654951
28Hepatoblastoma (HP:0002884)2.35559811
29Cortical dysplasia (HP:0002539)2.35540967
30Irregular epiphyses (HP:0010582)2.32170159
31Abnormality of cells of the erythroid lineage (HP:0012130)2.30412118
32Nephroblastoma (Wilms tumor) (HP:0002667)2.28669978
33Abnormal number of erythroid precursors (HP:0012131)2.27920461
34Abnormal hair whorl (HP:0010721)2.26609033
35Bone marrow hypocellularity (HP:0005528)2.25863340
36Duodenal stenosis (HP:0100867)2.21144884
37Small intestinal stenosis (HP:0012848)2.21144884
38Embryonal renal neoplasm (HP:0011794)2.18735498
39Increased nuchal translucency (HP:0010880)2.17455504
40Volvulus (HP:0002580)2.17404984
41Ependymoma (HP:0002888)2.16447056
42Colon cancer (HP:0003003)2.15902957
43Oral leukoplakia (HP:0002745)2.14710738
44Aplasia/Hypoplasia of the sternum (HP:0006714)2.14432135
45Microvesicular hepatic steatosis (HP:0001414)2.13700041
46Facial hemangioma (HP:0000329)2.11853948
47Premature graying of hair (HP:0002216)2.10452730
48Pancreatic fibrosis (HP:0100732)2.10193381
49Type I transferrin isoform profile (HP:0003642)2.09503609
5011 pairs of ribs (HP:0000878)2.08865288
51Abnormal lung lobation (HP:0002101)2.08555820
52Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.04975255
53Degeneration of the lateral corticospinal tracts (HP:0002314)2.04975255
54Sloping forehead (HP:0000340)2.02386519
55Neoplasm of the oral cavity (HP:0100649)2.01987040
56Focal motor seizures (HP:0011153)2.01660724
57Wide intermamillary distance (HP:0006610)1.98597749
58Diastasis recti (HP:0001540)1.96520397
59Absent radius (HP:0003974)1.95586901
60CNS hypomyelination (HP:0003429)1.95520403
61Absent eyebrow (HP:0002223)1.94988656
62Missing ribs (HP:0000921)1.94230068
63Atrophy/Degeneration involving motor neurons (HP:0007373)1.93649993
64Heterotopia (HP:0002282)1.93519940
65Reticulocytopenia (HP:0001896)1.93265347
66Horseshoe kidney (HP:0000085)1.93230859
67Type 2 muscle fiber atrophy (HP:0003554)1.93037181
68Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.91886380
69Rhabdomyosarcoma (HP:0002859)1.91774979
70Neoplasm of the small intestine (HP:0100833)1.90000572
71Cellular immunodeficiency (HP:0005374)1.88998384
72Homocystinuria (HP:0002156)1.88757916
73Abnormality of homocysteine metabolism (HP:0010919)1.88757916
74Abnormality of the corticospinal tract (HP:0002492)1.88219078
75Cleft eyelid (HP:0000625)1.88110176
76Biliary tract neoplasm (HP:0100574)1.87490367
77Poor coordination (HP:0002370)1.86824521
78Absent thumb (HP:0009777)1.85630544
79Abnormality of DNA repair (HP:0003254)1.85345586
80Hip dysplasia (HP:0001385)1.84654275
81Cafe-au-lait spot (HP:0000957)1.84563408
82Protruding tongue (HP:0010808)1.83002057
83Hypoplastic iliac wings (HP:0002866)1.82967818
84Aplasia involving forearm bones (HP:0009822)1.82684476
85Absent forearm bone (HP:0003953)1.82684476
86Abnormal trabecular bone morphology (HP:0100671)1.82225137
87Abnormality of the duodenum (HP:0002246)1.81017730
88Amyotrophic lateral sclerosis (HP:0007354)1.80811155
89Increased hepatocellular lipid droplets (HP:0006565)1.80691164
90Shoulder girdle muscle weakness (HP:0003547)1.78451316
91Lipid accumulation in hepatocytes (HP:0006561)1.78001670
92Thyroid carcinoma (HP:0002890)1.77368333
93Unsteady gait (HP:0002317)1.76977310
94Peripheral primitive neuroectodermal neoplasm (HP:0030067)1.76757325
95Neuroblastoma (HP:0003006)1.76757325
96Primitive neuroectodermal tumor (HP:0030065)1.76757325
97Neuroblastic tumors (HP:0004376)1.76757325
98Abnormal pancreas size (HP:0012094)1.75631883
99Drooling (HP:0002307)1.75212468
100Short thumb (HP:0009778)1.74772160
101Acute myeloid leukemia (HP:0004808)1.74668231
102Oligodactyly (HP:0012165)1.74316341
103Glioma (HP:0009733)1.72904605
104Bifid tongue (HP:0010297)1.72128237
105Ectopic kidney (HP:0000086)1.71414053
106Neoplasm of striated muscle (HP:0009728)1.71190592
107Clubbing of toes (HP:0100760)1.68969661
108Pancreatic cysts (HP:0001737)1.68767362
109Febrile seizures (HP:0002373)1.68334320
110High anterior hairline (HP:0009890)1.67818387
111Cystic hygroma (HP:0000476)1.67605584
112Nephrogenic diabetes insipidus (HP:0009806)1.66832294
113Impaired vibration sensation in the lower limbs (HP:0002166)1.66353048
114Gonadotropin excess (HP:0000837)1.65588891
115Tracheoesophageal fistula (HP:0002575)1.65072789
116Obsessive-compulsive behavior (HP:0000722)1.64740539
117Neoplasm of the adrenal cortex (HP:0100641)1.64215768
118Triphalangeal thumb (HP:0001199)1.64170631
119Atonic seizures (HP:0010819)1.63999793
120Selective tooth agenesis (HP:0001592)1.63938353
121Muscle fiber atrophy (HP:0100295)1.63661321
122Postnatal microcephaly (HP:0005484)1.63195157
123Long clavicles (HP:0000890)1.62881178
124Acute lymphatic leukemia (HP:0006721)1.62752943
125Genital tract atresia (HP:0001827)1.62643920
126Neoplasm of the pancreas (HP:0002894)1.62560303
127Neoplasm of the colon (HP:0100273)1.62378270
128Intestinal atresia (HP:0011100)1.61218543
129Septo-optic dysplasia (HP:0100842)1.60727159
130Facial cleft (HP:0002006)1.60395219
131Premature ovarian failure (HP:0008209)1.60372435
132Astrocytoma (HP:0009592)1.60284922
133Abnormality of the astrocytes (HP:0100707)1.60284922
134Tubulointerstitial nephritis (HP:0001970)1.59196381
135Breast aplasia (HP:0100783)1.58189787
136Abnormality of endocrine pancreas physiology (HP:0012093)1.57841430
137Abnormality of the pancreatic islet cells (HP:0006476)1.57841430
138Optic nerve coloboma (HP:0000588)1.57103635
139Small hand (HP:0200055)1.57094219
140Abnormality of the carotid arteries (HP:0005344)1.56816724
141Stenosis of the external auditory canal (HP:0000402)1.56517299
142Rectal fistula (HP:0100590)1.56294657
143Rectovaginal fistula (HP:0000143)1.56294657
144Renal cortical cysts (HP:0000803)1.56131616
145Abnormal number of incisors (HP:0011064)1.55920477
146Abnormality of the septum pellucidum (HP:0007375)1.55581283
147Methylmalonic acidemia (HP:0002912)1.55316302
148Abnormality of methionine metabolism (HP:0010901)1.54906172
149Spinal muscular atrophy (HP:0007269)1.54894986
150True hermaphroditism (HP:0010459)1.54258934
151Increased CSF lactate (HP:0002490)1.53424248
152Excessive salivation (HP:0003781)1.53171595
153Preaxial hand polydactyly (HP:0001177)1.53163177
154Basal cell carcinoma (HP:0002671)1.52922892
155Lymphoma (HP:0002665)1.52534627
156Abnormality of alanine metabolism (HP:0010916)1.52512120
157Hyperalaninemia (HP:0003348)1.52512120
158Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.52512120
159Pancreatic islet-cell hyperplasia (HP:0004510)1.51961973
160Deep palmar crease (HP:0006191)1.50065107
161Prominent metopic ridge (HP:0005487)1.49803171
162Medial flaring of the eyebrow (HP:0010747)1.47636389

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WEE13.58291652
2BUB13.45160343
3EIF2AK13.35563886
4TSSK63.03001729
5SRPK12.88434485
6CDC72.88005558
7EIF2AK32.69336266
8MKNK12.53181698
9STK392.25229125
10PLK32.20534935
11STK162.20379168
12MKNK22.19820375
13TRIM281.98133348
14AKT31.97956523
15BRSK21.97092918
16CDK121.94577593
17PLK41.94449791
18ACVR1B1.93431481
19MAP2K71.93124331
20LATS11.88235156
21MAP3K121.81532072
22MST41.78626354
23CCNB11.78449914
24ZAK1.72167433
25BCR1.71448865
26CAMK1G1.63953889
27ERBB31.60767991
28WNK31.58016919
29VRK11.57000074
30WNK41.56472318
31PLK11.55644007
32TTK1.54489676
33MAP3K41.54341551
34BRSK11.54316519
35CDK81.52628583
36OXSR11.50653814
37TAF11.42311519
38CASK1.40361006
39PLK21.39886472
40PNCK1.38371983
41BRAF1.37954433
42NEK11.33431434
43STK31.25960979
44CHEK21.25600622
45ATR1.25222157
46MARK11.21497995
47NLK1.17570116
48PRPF4B1.14601319
49MUSK1.12146305
50EIF2AK21.08363346
51BMPR21.08334776
52NUAK11.07268928
53MAP3K101.07059637
54ARAF1.06401191
55PIM21.04750062
56WNK11.04009088
57DAPK11.01989238
58MET1.00186586
59NEK20.97641635
60CDK190.96994450
61FGFR10.96193554
62PBK0.95111485
63CDK70.92657261
64DYRK30.92445174
65CSNK1E0.92340963
66PASK0.92092554
67NTRK30.90945930
68AURKB0.90050921
69TGFBR10.88774719
70NME10.88271382
71FLT30.86186916
72CHEK10.85862911
73AURKA0.84847146
74NME20.84412404
75TNIK0.83697896
76UHMK10.81123863
77ERBB40.77396652
78ATM0.76246849
79BMPR1B0.74622542
80MAPK130.74462298
81NEK60.74410521
82SIK30.73696104
83TLK10.73632480
84CAMKK20.71872792
85BRD40.71802491
86RPS6KB20.70700912
87RAF10.69238546
88CDK30.67853583
89MINK10.67624585
90* CDK20.64254499
91MAP4K20.62908553
92ALK0.62500040
93STK240.60078631
94RPS6KB10.58078499
95PIM10.57907040
96CSNK2A20.56467159
97KSR10.56234651
98MAP3K90.56064958
99MAP3K60.55975246
100CDK10.55728986
101LATS20.54577023
102CSNK2A10.54289022
103MAPK100.53522438
104DYRK20.53228651
105STK38L0.52459334
106PRKCI0.52450692
107CAMK1D0.52426605
108PRKDC0.51785888
109YES10.48693002
110CDK60.48646295
111SGK20.48612290
112CDK40.46821999
113PAK30.46156949
114SGK2230.45597987
115SGK4940.45597987
116RPS6KA40.42999526
117PRKCG0.41848217
118SGK30.41182907
119CDK180.40399669
120SCYL20.40348812
121SGK10.40023170
122CSNK1G10.40009412
123MAP3K20.39861586
124* GSK3B0.39834336
125MAPK140.37644938
126MELK0.37351377
127TXK0.36443699
128EPHA40.35766483
129TAOK20.34865713
130EPHA20.34627380
131STK40.34556281
132DYRK1A0.33258765
133CDK11A0.33176367
134CDK150.33048330
135TEC0.32630334
136PINK10.31894925
137RPS6KA50.31351330
138CDK140.29145324

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030303.78010172
2Mismatch repair_Homo sapiens_hsa034303.77318674
3Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.74878595
4RNA polymerase_Homo sapiens_hsa030203.73879766
5Proteasome_Homo sapiens_hsa030503.44097669
6Spliceosome_Homo sapiens_hsa030402.90495543
7RNA transport_Homo sapiens_hsa030132.84403505
8Nucleotide excision repair_Homo sapiens_hsa034202.74020942
9Homologous recombination_Homo sapiens_hsa034402.64232972
10Cell cycle_Homo sapiens_hsa041102.40601982
11Base excision repair_Homo sapiens_hsa034102.38745958
12Ribosome_Homo sapiens_hsa030102.32883245
13Basal transcription factors_Homo sapiens_hsa030222.25100549
14Pyrimidine metabolism_Homo sapiens_hsa002402.22869966
15Fanconi anemia pathway_Homo sapiens_hsa034602.18126206
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.13108275
17RNA degradation_Homo sapiens_hsa030182.05741928
18Non-homologous end-joining_Homo sapiens_hsa034501.80323554
19Selenocompound metabolism_Homo sapiens_hsa004501.74698839
20* mRNA surveillance pathway_Homo sapiens_hsa030151.68772281
21Purine metabolism_Homo sapiens_hsa002301.50922012
22Oocyte meiosis_Homo sapiens_hsa041141.44063517
23Nicotine addiction_Homo sapiens_hsa050331.43726693
24One carbon pool by folate_Homo sapiens_hsa006701.40824455
25Adherens junction_Homo sapiens_hsa045201.28068882
26Epstein-Barr virus infection_Homo sapiens_hsa051691.22134019
27p53 signaling pathway_Homo sapiens_hsa041151.20322550
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.14581792
29Propanoate metabolism_Homo sapiens_hsa006401.13030510
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.09982746
31Protein export_Homo sapiens_hsa030601.05160545
32Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.05106844
33Steroid biosynthesis_Homo sapiens_hsa001000.99981170
34Synaptic vesicle cycle_Homo sapiens_hsa047210.91524396
35Basal cell carcinoma_Homo sapiens_hsa052170.90376690
36Hedgehog signaling pathway_Homo sapiens_hsa043400.89995366
37Lysine degradation_Homo sapiens_hsa003100.88419725
38Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.87986672
39Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.86408941
40Huntingtons disease_Homo sapiens_hsa050160.81001997
41Vitamin B6 metabolism_Homo sapiens_hsa007500.79597847
42Long-term potentiation_Homo sapiens_hsa047200.78129455
43Prostate cancer_Homo sapiens_hsa052150.73002595
44Herpes simplex infection_Homo sapiens_hsa051680.69442871
45Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.67007370
46Alcoholism_Homo sapiens_hsa050340.66543553
47Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.64502834
48Thyroid cancer_Homo sapiens_hsa052160.64012016
49Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.64000623
50Long-term depression_Homo sapiens_hsa047300.63639357
51Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61788705
52Viral carcinogenesis_Homo sapiens_hsa052030.60947149
53Parkinsons disease_Homo sapiens_hsa050120.60337461
54Oxidative phosphorylation_Homo sapiens_hsa001900.59454825
55Systemic lupus erythematosus_Homo sapiens_hsa053220.59115134
56Type I diabetes mellitus_Homo sapiens_hsa049400.58416091
57Collecting duct acid secretion_Homo sapiens_hsa049660.58183048
58Amphetamine addiction_Homo sapiens_hsa050310.56718594
59Regulation of autophagy_Homo sapiens_hsa041400.56300525
60Colorectal cancer_Homo sapiens_hsa052100.54978353
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.54495132
62Renal cell carcinoma_Homo sapiens_hsa052110.54094290
63Melanogenesis_Homo sapiens_hsa049160.52587562
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.51446221
65Antigen processing and presentation_Homo sapiens_hsa046120.51246227
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.50368845
67Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.49884632
68Morphine addiction_Homo sapiens_hsa050320.49680500
69Serotonergic synapse_Homo sapiens_hsa047260.49070865
70Dorso-ventral axis formation_Homo sapiens_hsa043200.48720149
71Circadian entrainment_Homo sapiens_hsa047130.48664539
72Dopaminergic synapse_Homo sapiens_hsa047280.48139298
73Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.44390061
74HTLV-I infection_Homo sapiens_hsa051660.44317358
75Olfactory transduction_Homo sapiens_hsa047400.43432965
76Inositol phosphate metabolism_Homo sapiens_hsa005620.43261767
77Vibrio cholerae infection_Homo sapiens_hsa051100.40888789
78Taste transduction_Homo sapiens_hsa047420.40118075
79Glutamatergic synapse_Homo sapiens_hsa047240.39361255
80Glucagon signaling pathway_Homo sapiens_hsa049220.38984162
81Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.38795153
82GABAergic synapse_Homo sapiens_hsa047270.37617105
83Axon guidance_Homo sapiens_hsa043600.37479488
84Tight junction_Homo sapiens_hsa045300.37069801
85N-Glycan biosynthesis_Homo sapiens_hsa005100.36292080
86Cocaine addiction_Homo sapiens_hsa050300.35735734
87Phototransduction_Homo sapiens_hsa047440.35175102
88Circadian rhythm_Homo sapiens_hsa047100.34395642
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.33482751
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.33159540
91Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32951352
92Cardiac muscle contraction_Homo sapiens_hsa042600.32813585
93Glioma_Homo sapiens_hsa052140.32600076
94Chronic myeloid leukemia_Homo sapiens_hsa052200.32282277
95Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32227625
96Pyruvate metabolism_Homo sapiens_hsa006200.31253985
97Alzheimers disease_Homo sapiens_hsa050100.30438610
98Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.30166147
99Hepatitis B_Homo sapiens_hsa051610.30044169
100Legionellosis_Homo sapiens_hsa051340.29346619
101Pathways in cancer_Homo sapiens_hsa052000.28730910
102Estrogen signaling pathway_Homo sapiens_hsa049150.27501170
103TGF-beta signaling pathway_Homo sapiens_hsa043500.27354834
104MicroRNAs in cancer_Homo sapiens_hsa052060.27292787
105Transcriptional misregulation in cancer_Homo sapiens_hsa052020.27189641
106Melanoma_Homo sapiens_hsa052180.26118516
107Maturity onset diabetes of the young_Homo sapiens_hsa049500.25551850
108Insulin secretion_Homo sapiens_hsa049110.24662637
109FoxO signaling pathway_Homo sapiens_hsa040680.24662145
110Rheumatoid arthritis_Homo sapiens_hsa053230.24548144
111Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.24523845
112Pancreatic cancer_Homo sapiens_hsa052120.23782645
113Wnt signaling pathway_Homo sapiens_hsa043100.23596657
114Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.23175824
115Type II diabetes mellitus_Homo sapiens_hsa049300.22977333
116mTOR signaling pathway_Homo sapiens_hsa041500.22952688
117Small cell lung cancer_Homo sapiens_hsa052220.22951603
118Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22396311
119Allograft rejection_Homo sapiens_hsa053300.22377163
120Choline metabolism in cancer_Homo sapiens_hsa052310.22309790
121Longevity regulating pathway - mammal_Homo sapiens_hsa042110.22017219
122Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.21504437
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.21384648
124Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.20683679
125MAPK signaling pathway_Homo sapiens_hsa040100.20075096
126Calcium signaling pathway_Homo sapiens_hsa040200.19889971
127Oxytocin signaling pathway_Homo sapiens_hsa049210.19860079
128HIF-1 signaling pathway_Homo sapiens_hsa040660.19750024
129Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.19050559
130Fructose and mannose metabolism_Homo sapiens_hsa000510.18768191
131ErbB signaling pathway_Homo sapiens_hsa040120.18738808
132Measles_Homo sapiens_hsa051620.18704143
133Cholinergic synapse_Homo sapiens_hsa047250.18543255
134Endometrial cancer_Homo sapiens_hsa052130.18112146
135Neurotrophin signaling pathway_Homo sapiens_hsa047220.17466893
136Hippo signaling pathway_Homo sapiens_hsa043900.17358994
137Apoptosis_Homo sapiens_hsa042100.16894778
138Phosphatidylinositol signaling system_Homo sapiens_hsa040700.15519970
139Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.15390347

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