RNPS1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.00436172
2DNA strand elongation involved in DNA replication (GO:0006271)4.92843098
3DNA strand elongation (GO:0022616)4.69331094
4DNA replication initiation (GO:0006270)4.63936917
5telomere maintenance via semi-conservative replication (GO:0032201)4.59418434
6formation of translation preinitiation complex (GO:0001731)4.11700948
7protein localization to kinetochore (GO:0034501)4.10121278
8maturation of SSU-rRNA (GO:0030490)4.02595337
9telomere maintenance via recombination (GO:0000722)4.02455986
10DNA replication checkpoint (GO:0000076)3.96283891
11nucleobase biosynthetic process (GO:0046112)3.93172124
12DNA deamination (GO:0045006)3.90478400
13mitotic recombination (GO:0006312)3.88024783
14ribosomal small subunit assembly (GO:0000028)3.88006662
15mitotic metaphase plate congression (GO:0007080)3.85722560
16* negative regulation of mRNA processing (GO:0050686)3.75908482
17DNA replication-dependent nucleosome assembly (GO:0006335)3.75186256
18DNA replication-dependent nucleosome organization (GO:0034723)3.75186256
19mitotic nuclear envelope disassembly (GO:0007077)3.74205213
20telomere maintenance via telomere lengthening (GO:0010833)3.74204840
21regulation of mitochondrial translation (GO:0070129)3.72468654
22spliceosomal tri-snRNP complex assembly (GO:0000244)3.64578304
23CENP-A containing nucleosome assembly (GO:0034080)3.64068540
24chromatin remodeling at centromere (GO:0031055)3.63983776
25viral transcription (GO:0019083)3.63057240
26nucleotide-excision repair, DNA gap filling (GO:0006297)3.60817822
27purine nucleobase biosynthetic process (GO:0009113)3.58808690
28spliceosomal snRNP assembly (GO:0000387)3.58480726
29translational termination (GO:0006415)3.57234935
30ribosome biogenesis (GO:0042254)3.55829859
31deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.55606135
32protein localization to chromosome, centromeric region (GO:0071459)3.54472870
33DNA replication-independent nucleosome assembly (GO:0006336)3.52985921
34DNA replication-independent nucleosome organization (GO:0034724)3.52985921
35IMP biosynthetic process (GO:0006188)3.51384087
36nuclear envelope disassembly (GO:0051081)3.48511941
37membrane disassembly (GO:0030397)3.48511941
38regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.46277590
39regulation of translational fidelity (GO:0006450)3.46173296
40kinetochore organization (GO:0051383)3.44506257
41peptidyl-arginine N-methylation (GO:0035246)3.44181643
42* negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.40064349
43metaphase plate congression (GO:0051310)3.39445085
44translational initiation (GO:0006413)3.37839594
45ribonucleoprotein complex biogenesis (GO:0022613)3.37581463
46peptidyl-arginine omega-N-methylation (GO:0035247)3.36696425
47nuclear pore organization (GO:0006999)3.35890694
48translational elongation (GO:0006414)3.35804153
49establishment of integrated proviral latency (GO:0075713)3.35449120
50DNA topological change (GO:0006265)3.34571172
51ribosomal large subunit biogenesis (GO:0042273)3.33059022
52base-excision repair (GO:0006284)3.32582956
53histone H2A acetylation (GO:0043968)3.32174730
54mitotic sister chromatid segregation (GO:0000070)3.31017314
55folic acid-containing compound biosynthetic process (GO:0009396)3.29275968
56kinetochore assembly (GO:0051382)3.28985216
57attachment of spindle microtubules to kinetochore (GO:0008608)3.28350349
58* negative regulation of RNA splicing (GO:0033119)3.26042110
59DNA synthesis involved in DNA repair (GO:0000731)3.25666913
60mitotic chromosome condensation (GO:0007076)3.23693478
61* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.21384254
62ribosome assembly (GO:0042255)3.20212756
63* mRNA splicing, via spliceosome (GO:0000398)3.19322917
64* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)3.19322917
65* negative regulation of mRNA metabolic process (GO:1903312)3.19031427
66dosage compensation (GO:0007549)3.18540132
67* RNA splicing, via transesterification reactions (GO:0000375)3.18459140
68DNA ligation (GO:0006266)3.17929507
69negative regulation of chromosome segregation (GO:0051985)3.16993567
70rRNA processing (GO:0006364)3.16770273
71negative regulation of mitotic sister chromatid separation (GO:2000816)3.15185835
72negative regulation of mitotic sister chromatid segregation (GO:0033048)3.15185835
73negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.15185835
74negative regulation of sister chromatid segregation (GO:0033046)3.15185835
75viral mRNA export from host cell nucleus (GO:0046784)3.14957518
76spliceosomal complex assembly (GO:0000245)3.14198303
77pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.14150962
78ribosomal small subunit biogenesis (GO:0042274)3.13943406
79DNA duplex unwinding (GO:0032508)3.13084318
80anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.13053273
81DNA geometric change (GO:0032392)3.11892771
82histone arginine methylation (GO:0034969)3.11543357
83mitotic spindle assembly checkpoint (GO:0007094)3.11418101
84pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.11148152
85regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.10499276
86nuclear pore complex assembly (GO:0051292)3.09979596
87pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.09638458
88spindle assembly checkpoint (GO:0071173)3.09467204
89histone exchange (GO:0043486)3.09084151
90heterochromatin organization (GO:0070828)3.08314897
91sister chromatid segregation (GO:0000819)3.08170189
92negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.07820135
93establishment of chromosome localization (GO:0051303)3.07426516
94rRNA metabolic process (GO:0016072)3.06876448
95negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.06858598
96proline biosynthetic process (GO:0006561)3.06841257
97protein-DNA complex disassembly (GO:0032986)3.06341324
98nucleosome disassembly (GO:0006337)3.06341324
99postreplication repair (GO:0006301)3.06090851
100iron-sulfur cluster assembly (GO:0016226)3.06055272
101metallo-sulfur cluster assembly (GO:0031163)3.06055272
102maturation of 5.8S rRNA (GO:0000460)3.05121286
103IMP metabolic process (GO:0046040)3.04866439
104transcription-coupled nucleotide-excision repair (GO:0006283)3.04605350
105regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.03003697
106transcription from mitochondrial promoter (GO:0006390)3.01096531
107mitochondrial RNA metabolic process (GO:0000959)3.00075903
108L-serine metabolic process (GO:0006563)2.99268750
109spindle checkpoint (GO:0031577)2.99173363
110translesion synthesis (GO:0019985)2.98582471
111negative regulation of DNA-templated transcription, elongation (GO:0032785)2.97004822
112regulation of double-strand break repair via homologous recombination (GO:0010569)2.96034874
113positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.95418225
114cellular protein complex disassembly (GO:0043624)2.94840852
115regulation of spindle organization (GO:0090224)2.94432336
116rRNA transcription (GO:0009303)2.94300997
117* termination of RNA polymerase II transcription (GO:0006369)2.93950410
118SRP-dependent cotranslational protein targeting to membrane (GO:0006614)2.93931003
119mitotic spindle checkpoint (GO:0071174)2.93105918
120ATP-dependent chromatin remodeling (GO:0043044)2.92478136
121proteasome assembly (GO:0043248)2.92034758
122chromatin assembly or disassembly (GO:0006333)2.91995948
123regulation of chromosome segregation (GO:0051983)2.91623396
124pseudouridine synthesis (GO:0001522)2.91567425
125peptidyl-arginine methylation (GO:0018216)2.91109638
126tRNA aminoacylation for protein translation (GO:0006418)2.88785059
127cellular component biogenesis (GO:0044085)2.88784772
128pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.88745180
129regulation of mammary gland epithelial cell proliferation (GO:0033599)2.83010800
130tRNA aminoacylation (GO:0043039)2.82470303
131amino acid activation (GO:0043038)2.82470303
132nuclear envelope reassembly (GO:0031468)2.82162030
133mitotic nuclear envelope reassembly (GO:0007084)2.82162030
134negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.79939477
135pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.79602436
136somatic hypermutation of immunoglobulin genes (GO:0016446)2.79533173
137somatic diversification of immune receptors via somatic mutation (GO:0002566)2.79533173
138establishment of viral latency (GO:0019043)2.76984421
139oxidative phosphorylation (GO:0006119)2.72498013

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.73058004
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.46501913
3FOXM1_23109430_ChIP-Seq_U2OS_Human4.02805528
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.97053123
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.70349420
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.14553762
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.12476499
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.95441996
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.93076992
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.91157900
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.91099905
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.85189209
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.79699935
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.79152954
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.72814031
16XRN2_22483619_ChIP-Seq_HELA_Human2.62226270
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.47182765
18* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.41224783
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.26250029
20THAP11_20581084_ChIP-Seq_MESCs_Mouse2.15382798
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.14473819
22* VDR_23849224_ChIP-Seq_CD4+_Human2.13521694
23NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.10675338
24* TTF2_22483619_ChIP-Seq_HELA_Human2.02018601
25E2F1_21310950_ChIP-Seq_MCF-7_Human2.00004302
26* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.99181219
27MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.98279134
28CIITA_25753668_ChIP-Seq_RAJI_Human1.97805360
29* GABP_19822575_ChIP-Seq_HepG2_Human1.96872727
30DCP1A_22483619_ChIP-Seq_HELA_Human1.96658444
31EGR1_19374776_ChIP-ChIP_THP-1_Human1.95837119
32MYC_22102868_ChIP-Seq_BL_Human1.95389617
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.92975187
34AR_21909140_ChIP-Seq_LNCAP_Human1.92821297
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.91155451
36ELF1_17652178_ChIP-ChIP_JURKAT_Human1.90942655
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.83086731
38YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.80008918
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.79205631
40HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.77469468
41* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.73168323
42* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.70312465
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.68867391
44* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.66926651
45YY1_21170310_ChIP-Seq_MESCs_Mouse1.62082145
46* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62023897
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.60092855
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.59751727
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.55642441
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.53065372
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52708886
52KDM5A_27292631_Chip-Seq_BREAST_Human1.51095073
53* TP63_19390658_ChIP-ChIP_HaCaT_Human1.50447285
54RBPJ_22232070_ChIP-Seq_NCS_Mouse1.44243368
55ELK1_19687146_ChIP-ChIP_HELA_Human1.43340266
56E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40321973
57* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34698003
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33954503
59TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.33035622
60SOX2_18555785_ChIP-Seq_MESCs_Mouse1.31615362
61ZNF263_19887448_ChIP-Seq_K562_Human1.31093438
62* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.27244902
63KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.26106092
64SRF_21415370_ChIP-Seq_HL-1_Mouse1.25477506
65DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.21487608
66KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20924883
67* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.20056931
68* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19553633
69TET1_21451524_ChIP-Seq_MESCs_Mouse1.19512204
70ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.18294810
71POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.18181392
72ESR1_15608294_ChIP-ChIP_MCF-7_Human1.17208434
73CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.17169725
74SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.16862042
75CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.15149636
76SRY_22984422_ChIP-ChIP_TESTIS_Rat1.15026564
77* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.14557853
78FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.14268465
79* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13110775
80P68_20966046_ChIP-Seq_HELA_Human1.11599932
81VDR_21846776_ChIP-Seq_THP-1_Human1.09914964
82TFEB_21752829_ChIP-Seq_HELA_Human1.09011251
83PADI4_21655091_ChIP-ChIP_MCF-7_Human1.08607292
84CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.08284029
85PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.06226368
86ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.06086211
87* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05250382
88ELF1_20517297_ChIP-Seq_JURKAT_Human1.03305056
89MYC_18940864_ChIP-ChIP_HL60_Human1.01618802
90STAT3_1855785_ChIP-Seq_MESCs_Mouse1.00939839
91PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.98700341
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97686424
93TBX5_21415370_ChIP-Seq_HL-1_Mouse0.95524276
94NOTCH1_21737748_ChIP-Seq_TLL_Human0.94689764
95NANOG_21062744_ChIP-ChIP_HESCs_Human0.94067940
96BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93988856
97KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.91982311
98SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91818958
99HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.91282382
100CTCF_18555785_ChIP-Seq_MESCs_Mouse0.91195286
101SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.90841632
102* LXR_22292898_ChIP-Seq_THP-1_Human0.90145324
103* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.89541933
104MAF_26560356_Chip-Seq_TH2_Human0.89359335
105CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.88880778
106ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.88464369
107* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.85917505
108TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85064229
109SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.85009898
110DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83463608
111SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.81776980
112OCT4_18692474_ChIP-Seq_MEFs_Mouse0.80864249
113ELK1_22589737_ChIP-Seq_MCF10A_Human0.79671742
114TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.76603813
115CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.75931963
116CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.74960344
117* FOXP1_21924763_ChIP-Seq_HESCs_Human0.73068278

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.15279563
2MP0010094_abnormal_chromosome_stability4.62981787
3MP0003111_abnormal_nucleus_morphology4.47848933
4MP0004957_abnormal_blastocyst_morpholog4.36762621
5MP0003077_abnormal_cell_cycle4.04893694
6MP0008057_abnormal_DNA_replication3.50699477
7MP0008058_abnormal_DNA_repair3.34556134
8MP0008007_abnormal_cellular_replicative2.90976344
9MP0003123_paternal_imprinting2.77536420
10MP0008932_abnormal_embryonic_tissue2.71200412
11MP0001730_embryonic_growth_arrest2.46906123
12MP0008877_abnormal_DNA_methylation2.41815381
13MP0002396_abnormal_hematopoietic_system2.38819338
14MP0000350_abnormal_cell_proliferation2.32618360
15MP0010030_abnormal_orbit_morphology2.18746229
16MP0003121_genomic_imprinting2.01634966
17MP0002653_abnormal_ependyma_morphology1.95165208
18MP0001697_abnormal_embryo_size1.83676633
19MP0001346_abnormal_lacrimal_gland1.83009512
20MP0003786_premature_aging1.81041331
21MP0010352_gastrointestinal_tract_polyps1.76115926
22MP0001672_abnormal_embryogenesis/_devel1.72756200
23MP0005380_embryogenesis_phenotype1.72756200
24MP0002085_abnormal_embryonic_tissue1.71237668
25MP0002080_prenatal_lethality1.65263870
26MP0002084_abnormal_developmental_patter1.62385459
27MP0001188_hyperpigmentation1.59332508
28MP0006292_abnormal_olfactory_placode1.58958096
29MP0003890_abnormal_embryonic-extraembry1.58313894
30MP0003984_embryonic_growth_retardation1.57552459
31MP0000490_abnormal_crypts_of1.54711626
32MP0000313_abnormal_cell_death1.53884681
33MP0002088_abnormal_embryonic_growth/wei1.53467971
34MP0004808_abnormal_hematopoietic_stem1.49171772
35MP0000537_abnormal_urethra_morphology1.49165964
36MP0006036_abnormal_mitochondrial_physio1.47014163
37MP0010307_abnormal_tumor_latency1.46129107
38MP0003119_abnormal_digestive_system1.45645326
39MP0003315_abnormal_perineum_morphology1.44747067
40MP0000678_abnormal_parathyroid_gland1.44686068
41MP0001293_anophthalmia1.42990435
42MP0004197_abnormal_fetal_growth/weight/1.42870128
43MP0004147_increased_porphyrin_level1.38854289
44MP0003567_abnormal_fetal_cardiomyocyte1.30984236
45MP0002019_abnormal_tumor_incidence1.30950364
46MP0002086_abnormal_extraembryonic_tissu1.27748465
47MP0004133_heterotaxia1.27225666
48MP0002210_abnormal_sex_determination1.26821212
49MP0003122_maternal_imprinting1.26105484
50MP0005076_abnormal_cell_differentiation1.25930050
51MP0002102_abnormal_ear_morphology1.23272087
52MP0002822_catalepsy1.19854109
53MP0009053_abnormal_anal_canal1.19561754
54MP0008789_abnormal_olfactory_epithelium1.17375881
55MP0000703_abnormal_thymus_morphology1.12659625
56MP0003763_abnormal_thymus_physiology1.09549837
57MP0001145_abnormal_male_reproductive1.08612908
58MP0009333_abnormal_splenocyte_physiolog1.04385004
59MP0003718_maternal_effect1.02425785
60MP0002160_abnormal_reproductive_system1.00355676
61MP0005397_hematopoietic_system_phenotyp0.96609698
62MP0001545_abnormal_hematopoietic_system0.96609698
63MP0001529_abnormal_vocalization0.96507925
64MP0005501_abnormal_skin_physiology0.96055952
65MP0003698_abnormal_male_reproductive0.94043956
66MP0002398_abnormal_bone_marrow0.92332044
67MP0003861_abnormal_nervous_system0.92273781
68MP0005499_abnormal_olfactory_system0.91474626
69MP0005394_taste/olfaction_phenotype0.91474626
70MP0001929_abnormal_gametogenesis0.90540713
71MP0002938_white_spotting0.90510844
72MP0009672_abnormal_birth_weight0.90378566
73MP0000653_abnormal_sex_gland0.90219624
74MP0000358_abnormal_cell_content/0.89398746
75MP0000049_abnormal_middle_ear0.86808328
76MP0000003_abnormal_adipose_tissue0.86301152
77MP0002751_abnormal_autonomic_nervous0.86114447
78MP0002111_abnormal_tail_morphology0.82840413
79MP0003937_abnormal_limbs/digits/tail_de0.82025631
80MP0002722_abnormal_immune_system0.80898145
81MP0000428_abnormal_craniofacial_morphol0.80609838
82MP0002163_abnormal_gland_morphology0.80569086
83MP0004233_abnormal_muscle_weight0.80399268
84MP0001286_abnormal_eye_development0.80267523
85MP0001119_abnormal_female_reproductive0.79012377
86MP0002161_abnormal_fertility/fecundity0.78379788
87MP0002132_abnormal_respiratory_system0.78218570
88MP0003787_abnormal_imprinting0.78007039
89MP0003186_abnormal_redox_activity0.77681056
90MP0005384_cellular_phenotype0.76413079
91MP0000566_synostosis0.76398242
92MP0003283_abnormal_digestive_organ0.76263968
93MP0008995_early_reproductive_senescence0.75149402
94MP0003385_abnormal_body_wall0.74491545
95MP0004185_abnormal_adipocyte_glucose0.73264568
96MP0001270_distended_abdomen0.72929849
97MP0003221_abnormal_cardiomyocyte_apopto0.71433448
98MP0005645_abnormal_hypothalamus_physiol0.71360924
99MP0003115_abnormal_respiratory_system0.70668346
100MP0000689_abnormal_spleen_morphology0.70407874
101MP0001661_extended_life_span0.69686446
102MP0005389_reproductive_system_phenotype0.69246595
103MP0009278_abnormal_bone_marrow0.69107798
104MP0004859_abnormal_synaptic_plasticity0.69106035
105MP0002234_abnormal_pharynx_morphology0.68815934
106MP0002092_abnormal_eye_morphology0.68811961
107MP0005423_abnormal_somatic_nervous0.68707610
108MP0003699_abnormal_female_reproductive0.68300232
109MP0009379_abnormal_foot_pigmentation0.68097552
110MP0003942_abnormal_urinary_system0.67940844
111MP0002932_abnormal_joint_morphology0.67691024
112MP0006054_spinal_hemorrhage0.67173457
113MP0002697_abnormal_eye_size0.66629829
114MP0009697_abnormal_copulation0.65113069
115MP0002429_abnormal_blood_cell0.64975723
116MP0001915_intracranial_hemorrhage0.64525725
117MP0000681_abnormal_thyroid_gland0.64251971
118MP0003943_abnormal_hepatobiliary_system0.63382515
119MP0008260_abnormal_autophagy0.62601842
120MP0001849_ear_inflammation0.62588369
121MP0005621_abnormal_cell_physiology0.60300057
122MP0004811_abnormal_neuron_physiology0.59920837
123MP0006035_abnormal_mitochondrial_morpho0.59521999
124MP0003938_abnormal_ear_development0.59038220
125MP0002114_abnormal_axial_skeleton0.58594706
126MP0009703_decreased_birth_body0.56936839
127MP0003935_abnormal_craniofacial_develop0.55571885
128MP0008770_decreased_survivor_rate0.53907772
129MP0002249_abnormal_larynx_morphology0.53759300

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.39849020
2Abnormality of cells of the erythroid lineage (HP:0012130)3.82136117
3Reticulocytopenia (HP:0001896)3.79212761
4Microvesicular hepatic steatosis (HP:0001414)3.77506156
5Abnormal number of erythroid precursors (HP:0012131)3.65015146
6Colon cancer (HP:0003003)3.63876363
7Patellar aplasia (HP:0006443)3.55920252
8Oral leukoplakia (HP:0002745)3.55756586
9Degeneration of anterior horn cells (HP:0002398)3.48614688
10Abnormality of the anterior horn cell (HP:0006802)3.48614688
11Aplasia/Hypoplasia of the patella (HP:0006498)3.36354675
12Abnormal number of incisors (HP:0011064)3.31077419
13Progressive muscle weakness (HP:0003323)3.30627306
14Medulloblastoma (HP:0002885)3.25706309
15Aplastic anemia (HP:0001915)3.12954023
16Selective tooth agenesis (HP:0001592)3.12285834
17Ependymoma (HP:0002888)3.11130794
18Ragged-red muscle fibers (HP:0003200)3.09536547
19Breast hypoplasia (HP:0003187)3.04961805
20Cerebral hypomyelination (HP:0006808)2.90284069
21Chromsome breakage (HP:0040012)2.85999237
22Abnormality of glycolysis (HP:0004366)2.85396321
23Abnormality of the labia minora (HP:0012880)2.82626905
24Rough bone trabeculation (HP:0100670)2.81698440
25Meckel diverticulum (HP:0002245)2.75519411
26Absent thumb (HP:0009777)2.75089960
27Abnormality of the ileum (HP:0001549)2.75071485
28Chromosomal breakage induced by crosslinking agents (HP:0003221)2.74028357
29Testicular atrophy (HP:0000029)2.73293043
30Broad distal phalanx of finger (HP:0009836)2.72471437
31Abnormality of the preputium (HP:0100587)2.67799589
32Carpal bone hypoplasia (HP:0001498)2.67399661
33Increased intramyocellular lipid droplets (HP:0012240)2.66440868
34Aplasia/Hypoplasia of the uvula (HP:0010293)2.62749263
35Multiple enchondromatosis (HP:0005701)2.59951666
36Small intestinal stenosis (HP:0012848)2.58665953
37Duodenal stenosis (HP:0100867)2.58665953
38Abnormal mitochondria in muscle tissue (HP:0008316)2.57740082
39Abnormality of chromosome stability (HP:0003220)2.56235598
40Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.54296050
41Decreased activity of mitochondrial respiratory chain (HP:0008972)2.54296050
42Neoplasm of the pancreas (HP:0002894)2.52512212
43Premature graying of hair (HP:0002216)2.47616305
44Type I transferrin isoform profile (HP:0003642)2.47092610
45Increased serum pyruvate (HP:0003542)2.46454410
4611 pairs of ribs (HP:0000878)2.46268858
47Increased nuchal translucency (HP:0010880)2.46119511
48Abnormal lung lobation (HP:0002101)2.45417184
49Abnormality of reticulocytes (HP:0004312)2.44296779
50Increased muscle lipid content (HP:0009058)2.44137664
51Abnormality of cochlea (HP:0000375)2.41981248
52Myelodysplasia (HP:0002863)2.38034706
53Increased serum lactate (HP:0002151)2.37689478
54Pallor (HP:0000980)2.37634648
55Aplasia/Hypoplasia of the sacrum (HP:0008517)2.36821288
56Hepatocellular necrosis (HP:0001404)2.33092063
57Microretrognathia (HP:0000308)2.32710087
58Atrophy/Degeneration involving motor neurons (HP:0007373)2.30163825
59Supernumerary spleens (HP:0009799)2.29636754
60Absent radius (HP:0003974)2.28678146
61Horseshoe kidney (HP:0000085)2.28313523
62Tracheoesophageal fistula (HP:0002575)2.27642725
63Agnosia (HP:0010524)2.26931413
64Cellular immunodeficiency (HP:0005374)2.26803517
65Atresia of the external auditory canal (HP:0000413)2.23061371
66Abnormal protein glycosylation (HP:0012346)2.20617088
67Abnormal glycosylation (HP:0012345)2.20617088
68Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.20617088
69Abnormal protein N-linked glycosylation (HP:0012347)2.20617088
70Proximal placement of thumb (HP:0009623)2.19915002
71Trismus (HP:0000211)2.19703352
72Ectopic kidney (HP:0000086)2.19182719
73Macrocytic anemia (HP:0001972)2.18601272
74Duplicated collecting system (HP:0000081)2.18504128
75Rhabdomyosarcoma (HP:0002859)2.18351843
76Pancytopenia (HP:0001876)2.18168905
77Abnormality of the duodenum (HP:0002246)2.16521535
78Duplication of thumb phalanx (HP:0009942)2.16466651
79Absent forearm bone (HP:0003953)2.16440808
80Aplasia involving forearm bones (HP:0009822)2.16440808
81Abnormality of DNA repair (HP:0003254)2.15532370
82Bone marrow hypocellularity (HP:0005528)2.15285308
83Optic nerve coloboma (HP:0000588)2.14226921
84Hypoplasia of the pons (HP:0012110)2.12777034
85Increased CSF lactate (HP:0002490)2.12146476
86Triphalangeal thumb (HP:0001199)2.10705601
87Progressive microcephaly (HP:0000253)2.09994810
88Acute necrotizing encephalopathy (HP:0006965)2.08833341
89Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.07651125
90Basal cell carcinoma (HP:0002671)2.06143031
91Abnormality of the astrocytes (HP:0100707)2.03294981
92Astrocytoma (HP:0009592)2.03294981
93Aplasia/Hypoplasia of the sternum (HP:0006714)2.02432278
94Cleft eyelid (HP:0000625)2.02118597
95Hepatic necrosis (HP:0002605)2.01891808
96Acute encephalopathy (HP:0006846)2.01818264
97Sloping forehead (HP:0000340)2.01768382
98High anterior hairline (HP:0009890)2.00206153
99Deviation of the thumb (HP:0009603)1.99823655
100Truncus arteriosus (HP:0001660)1.99780273
101Abnormality of the carotid arteries (HP:0005344)1.99351450
102Short 4th metacarpal (HP:0010044)1.98618640
103Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.98618640
104Slender long bone (HP:0003100)1.98305044
105Glioma (HP:0009733)1.97639434
106Mitochondrial inheritance (HP:0001427)1.97403640
107Retinal dysplasia (HP:0007973)1.96955059
108Lactic acidosis (HP:0003128)1.93551106
109Renal duplication (HP:0000075)1.93208895
110Premature ovarian failure (HP:0008209)1.92754173
111Progressive external ophthalmoplegia (HP:0000590)1.91933639
112Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.90712374
113Insomnia (HP:0100785)1.90073772
114Abnormal trabecular bone morphology (HP:0100671)1.89543229
115Pelvic girdle muscle weakness (HP:0003749)1.89059911
116Abnormality of the renal collecting system (HP:0004742)1.88842521
117Exercise intolerance (HP:0003546)1.88443693
118Volvulus (HP:0002580)1.86210196
119Poikiloderma (HP:0001029)1.85574498
120Missing ribs (HP:0000921)1.84509169
121Absent epiphyses (HP:0010577)1.83795093
122Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.83795093
123Abnormality of the pons (HP:0007361)1.82790744
124Overlapping toe (HP:0001845)1.82307047
125Overriding aorta (HP:0002623)1.82133589
126Septate vagina (HP:0001153)1.82052537
127Shoulder girdle muscle weakness (HP:0003547)1.82007040
128Short thumb (HP:0009778)1.80451815
129Trigonocephaly (HP:0000243)1.79941297
130Hypoplasia of the capital femoral epiphysis (HP:0003090)1.79715043
131Facial hemangioma (HP:0000329)1.79451353
132Nephroblastoma (Wilms tumor) (HP:0002667)1.78342565
133Morphological abnormality of the inner ear (HP:0011390)1.77873020
134Abnormality of abdominal situs (HP:0011620)1.77794728
135Abdominal situs inversus (HP:0003363)1.77794728
136Hypoplasia of the radius (HP:0002984)1.77199466
137Cafe-au-lait spot (HP:0000957)1.77056205
138Neoplasm of striated muscle (HP:0009728)1.77052737
139Pendular nystagmus (HP:0012043)1.76853805
140Lipid accumulation in hepatocytes (HP:0006561)1.76483998
141Neoplasm of the oral cavity (HP:0100649)1.76116215
142Prominent nose (HP:0000448)1.76079912
143Impulsivity (HP:0100710)1.75956520
144Ureteral duplication (HP:0000073)1.75760346
145Deep palmar crease (HP:0006191)1.75525049
146Glossoptosis (HP:0000162)1.74787616
147Neoplasm of the colon (HP:0100273)1.72595917
148Acute lymphatic leukemia (HP:0006721)1.71724344
149Reduced antithrombin III activity (HP:0001976)1.71547195
150Hyperacusis (HP:0010780)1.71544015
151Cholecystitis (HP:0001082)1.71522458
152Abnormal gallbladder physiology (HP:0012438)1.71522458
153Amaurosis fugax (HP:0100576)1.70601421
154Lymphoma (HP:0002665)1.69955922
155Facial cleft (HP:0002006)1.69245767
156Squamous cell carcinoma (HP:0002860)1.69197860

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.77059122
2CDC74.50390966
3WEE14.19962483
4VRK23.79064177
5BCKDK2.88376107
6EIF2AK12.86178697
7NEK22.82710864
8TSSK62.77112929
9PASK2.67692310
10SRPK12.52016861
11NEK12.50718356
12SMG12.44682849
13TESK22.32232514
14ACVR1B2.21129705
15MAP3K102.13750190
16TTK2.00590230
17DYRK31.92718624
18PLK11.92363410
19VRK11.82105272
20ATR1.81357248
21STK161.81274193
22MKNK11.80627446
23CCNB11.77683643
24CDK71.72170669
25BRSK21.71909279
26PLK41.68533853
27PBK1.61923148
28TRIB31.60467452
29AURKB1.57425851
30PLK31.56890391
31EEF2K1.56086128
32BRSK11.55762149
33TGFBR11.52140217
34NME21.48621437
35TLK11.45226927
36RPS6KA41.42580573
37ARAF1.39332560
38EIF2AK31.38114325
39AURKA1.35373388
40CHEK21.35241849
41SCYL21.32397135
42RPS6KB21.31142319
43SIK31.29293425
44CDK41.25419403
45CDK121.25211431
46CHEK11.21558564
47PAK41.19784305
48MKNK21.13072485
49MAP3K81.12255931
50PDK21.02129516
51TESK10.99540363
52IRAK30.95911627
53DAPK10.92988874
54CDK20.91832059
55CDK80.86965704
56KSR10.85294536
57ERN10.84972018
58PKN20.84612057
59DYRK20.84424351
60BRAF0.81294520
61ICK0.79887854
62ATM0.78992428
63MAP3K110.78701076
64STK100.76294036
65BRD40.75553234
66PRPF4B0.75364249
67CDK190.72640003
68TAOK20.70926868
69PIM20.70626950
70ALK0.70125240
71PAK10.70007630
72CDK10.67581376
73TAF10.67334787
74CSNK2A20.63878886
75MAPKAPK30.63822434
76UHMK10.63155247
77KDR0.63103618
78LIMK10.61850749
79CSNK1A1L0.61476987
80MAPK110.58505557
81* CSNK2A10.56867424
82NUAK10.55884404
83LRRK20.54182636
84MAP2K20.54151648
85STK40.53283484
86TRIM280.53221449
87BMX0.52713840
88PIM10.50903975
89ILK0.49599870
90MAP3K90.49155414
91CSNK1G10.49107319
92AKT20.48861990
93MAPKAPK50.48520549
94SIK20.48326623
95MAP4K10.47165579
96FGFR10.45967787
97PRKCI0.45221256
98ERBB30.43930112
99CSNK1G20.42483989
100CDK90.41756737
101CDK180.41202768
102FLT30.41045209
103CSNK1E0.39934144
104RAF10.39610087
105MAPK140.38959015
106CDK11A0.37654678
107CLK10.37478628
108RPS6KA50.35345398
109CDK150.35011145
110NME10.35009879
111BTK0.33604378
112PNCK0.32558190
113CDK60.32445965
114EIF2AK20.31715125
115PRKDC0.31403587
116MELK0.31332891
117GRK60.31125792
118CDK140.30857391
119EPHA20.30280731
120MTOR0.29679724
121CSNK1G30.26763949
122BCR0.25322454
123MAPK90.25189884
124RPS6KA10.24777556
125ZAK0.23976545

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.19347117
2Mismatch repair_Homo sapiens_hsa034304.25636940
3Spliceosome_Homo sapiens_hsa030403.69430962
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.41814723
5Base excision repair_Homo sapiens_hsa034103.34549530
6Ribosome_Homo sapiens_hsa030103.31167714
7Proteasome_Homo sapiens_hsa030503.14810458
8RNA polymerase_Homo sapiens_hsa030203.12673583
9* RNA transport_Homo sapiens_hsa030133.11043836
10Homologous recombination_Homo sapiens_hsa034402.93236102
11Nucleotide excision repair_Homo sapiens_hsa034202.87969566
12Cell cycle_Homo sapiens_hsa041102.85199861
13Pyrimidine metabolism_Homo sapiens_hsa002402.44254802
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.43625053
15One carbon pool by folate_Homo sapiens_hsa006702.13602755
16Fanconi anemia pathway_Homo sapiens_hsa034602.02650215
17RNA degradation_Homo sapiens_hsa030181.98477545
18* mRNA surveillance pathway_Homo sapiens_hsa030151.93899943
19Basal transcription factors_Homo sapiens_hsa030221.87257923
20Non-homologous end-joining_Homo sapiens_hsa034501.78836467
21Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.63185308
22p53 signaling pathway_Homo sapiens_hsa041151.47107871
23Purine metabolism_Homo sapiens_hsa002301.32719485
24Oocyte meiosis_Homo sapiens_hsa041141.28620747
25Epstein-Barr virus infection_Homo sapiens_hsa051691.28437650
26Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.15794831
27Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.10634301
28Pyruvate metabolism_Homo sapiens_hsa006201.04448785
29Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.95300303
30Fatty acid elongation_Homo sapiens_hsa000620.93034663
31Viral carcinogenesis_Homo sapiens_hsa052030.92813108
32Systemic lupus erythematosus_Homo sapiens_hsa053220.92685827
33HTLV-I infection_Homo sapiens_hsa051660.91512951
34Vitamin B6 metabolism_Homo sapiens_hsa007500.91315782
35Herpes simplex infection_Homo sapiens_hsa051680.90983162
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.89440423
37Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.87454419
38Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.85271155
39Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.84474662
40Colorectal cancer_Homo sapiens_hsa052100.80912732
41Basal cell carcinoma_Homo sapiens_hsa052170.80272673
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.74422955
43Antigen processing and presentation_Homo sapiens_hsa046120.71759154
44Thyroid cancer_Homo sapiens_hsa052160.70463026
45Hippo signaling pathway_Homo sapiens_hsa043900.66548757
46Biosynthesis of amino acids_Homo sapiens_hsa012300.66354204
47MicroRNAs in cancer_Homo sapiens_hsa052060.64759385
48Cysteine and methionine metabolism_Homo sapiens_hsa002700.64442886
49Alcoholism_Homo sapiens_hsa050340.64220323
50Notch signaling pathway_Homo sapiens_hsa043300.63349752
51Lysine degradation_Homo sapiens_hsa003100.61499492
52Huntingtons disease_Homo sapiens_hsa050160.60543661
53Alzheimers disease_Homo sapiens_hsa050100.59987939
54Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.58989798
55Hedgehog signaling pathway_Homo sapiens_hsa043400.57816714
56Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55471980
57N-Glycan biosynthesis_Homo sapiens_hsa005100.55363543
58Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51546712
59Primary immunodeficiency_Homo sapiens_hsa053400.51536159
60Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51226528
61Chronic myeloid leukemia_Homo sapiens_hsa052200.51075864
62Small cell lung cancer_Homo sapiens_hsa052220.50345066
63Legionellosis_Homo sapiens_hsa051340.50211701
64Transcriptional misregulation in cancer_Homo sapiens_hsa052020.49768129
65Pentose phosphate pathway_Homo sapiens_hsa000300.47245341
66Parkinsons disease_Homo sapiens_hsa050120.46745129
67Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.46505529
68Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.46309283
69Metabolic pathways_Homo sapiens_hsa011000.45987563
70Shigellosis_Homo sapiens_hsa051310.45764942
71Sulfur relay system_Homo sapiens_hsa041220.45643514
72Apoptosis_Homo sapiens_hsa042100.45611536
73Hepatitis B_Homo sapiens_hsa051610.41625726
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.39992304
75TGF-beta signaling pathway_Homo sapiens_hsa043500.39506706
76Arginine and proline metabolism_Homo sapiens_hsa003300.39096700
77Wnt signaling pathway_Homo sapiens_hsa043100.36582976
78Central carbon metabolism in cancer_Homo sapiens_hsa052300.35674124
79Viral myocarditis_Homo sapiens_hsa054160.34926650
80Pathways in cancer_Homo sapiens_hsa052000.34751020
81Bladder cancer_Homo sapiens_hsa052190.34521079
82Selenocompound metabolism_Homo sapiens_hsa004500.34026845
83Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33992206
84Folate biosynthesis_Homo sapiens_hsa007900.33772192
85HIF-1 signaling pathway_Homo sapiens_hsa040660.33557816
86Non-small cell lung cancer_Homo sapiens_hsa052230.33416965
87Protein export_Homo sapiens_hsa030600.33182092
88mTOR signaling pathway_Homo sapiens_hsa041500.32035162
89Synaptic vesicle cycle_Homo sapiens_hsa047210.31675822
90Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.30646950
91Acute myeloid leukemia_Homo sapiens_hsa052210.30339181
92Endometrial cancer_Homo sapiens_hsa052130.28842331
932-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.28430289
94Cardiac muscle contraction_Homo sapiens_hsa042600.28188223
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.27717349
96Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.27571684
97Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.27463097
98Glutathione metabolism_Homo sapiens_hsa004800.27444564
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.27420344
100Drug metabolism - other enzymes_Homo sapiens_hsa009830.25415808
101Measles_Homo sapiens_hsa051620.25160745
102Neurotrophin signaling pathway_Homo sapiens_hsa047220.25111351
103Carbon metabolism_Homo sapiens_hsa012000.24584161
104Fatty acid metabolism_Homo sapiens_hsa012120.24526602
105Thyroid hormone signaling pathway_Homo sapiens_hsa049190.23866193
106Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.23788764
107Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.23019080
108Steroid biosynthesis_Homo sapiens_hsa001000.22462528
109Pancreatic cancer_Homo sapiens_hsa052120.20400166
110Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.20366178
111Longevity regulating pathway - mammal_Homo sapiens_hsa042110.19439569
112T cell receptor signaling pathway_Homo sapiens_hsa046600.19395274
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18874243
114Influenza A_Homo sapiens_hsa051640.18262349
115Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.16780576
116Vibrio cholerae infection_Homo sapiens_hsa051100.16274591
117AMPK signaling pathway_Homo sapiens_hsa041520.15854814
118Fructose and mannose metabolism_Homo sapiens_hsa000510.15100730
119Adherens junction_Homo sapiens_hsa045200.12284919
120Propanoate metabolism_Homo sapiens_hsa006400.11814463
121Oxidative phosphorylation_Homo sapiens_hsa001900.10347875
122NF-kappa B signaling pathway_Homo sapiens_hsa040640.09957618
123VEGF signaling pathway_Homo sapiens_hsa043700.09272864
124Prostate cancer_Homo sapiens_hsa052150.08432749
125Asthma_Homo sapiens_hsa053100.08139796
126Galactose metabolism_Homo sapiens_hsa000520.07794963
127Nicotine addiction_Homo sapiens_hsa050330.07604731
128Hematopoietic cell lineage_Homo sapiens_hsa046400.07258747
129Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.07227738

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »