ROBO2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleobase catabolic process (GO:0046113)5.27876772
2regulation of short-term neuronal synaptic plasticity (GO:0048172)5.25519458
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.11479863
4synaptic vesicle maturation (GO:0016188)4.67800905
5glutamate secretion (GO:0014047)4.66279316
6neuron cell-cell adhesion (GO:0007158)4.65905519
7synaptic vesicle exocytosis (GO:0016079)4.56438461
8regulation of synaptic vesicle exocytosis (GO:2000300)4.45276512
9protein localization to synapse (GO:0035418)4.42304657
10vocalization behavior (GO:0071625)4.41328610
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.38662512
12locomotory exploration behavior (GO:0035641)4.30573946
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.29561971
14limb bud formation (GO:0060174)4.22361878
15synaptic vesicle docking involved in exocytosis (GO:0016081)4.20774189
16layer formation in cerebral cortex (GO:0021819)4.15150412
17ionotropic glutamate receptor signaling pathway (GO:0035235)4.14523810
18positive regulation of synapse maturation (GO:0090129)4.07725740
19regulation of glutamate receptor signaling pathway (GO:1900449)4.02678930
20* neuron recognition (GO:0008038)3.94176423
21axonal fasciculation (GO:0007413)3.93464393
22regulation of synaptic vesicle transport (GO:1902803)3.91827127
23glutamate receptor signaling pathway (GO:0007215)3.89569828
24synaptic transmission, glutamatergic (GO:0035249)3.88475659
25neurotransmitter-gated ion channel clustering (GO:0072578)3.88380302
26exploration behavior (GO:0035640)3.81588239
27regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.80918522
28response to pheromone (GO:0019236)3.78692822
29neurotransmitter secretion (GO:0007269)3.72326024
30regulation of synapse structural plasticity (GO:0051823)3.71403711
31neuron-neuron synaptic transmission (GO:0007270)3.69316715
32central nervous system neuron axonogenesis (GO:0021955)3.62533435
33negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.61521223
34innervation (GO:0060384)3.61260255
35sympathetic nervous system development (GO:0048485)3.55024737
36postsynaptic membrane organization (GO:0001941)3.52442629
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49658551
38regulation of neuronal synaptic plasticity (GO:0048168)3.49007982
39cerebral cortex radially oriented cell migration (GO:0021799)3.47088147
40regulation of feeding behavior (GO:0060259)3.44431237
41regulation of long-term neuronal synaptic plasticity (GO:0048169)3.39417145
42positive regulation of dendritic spine morphogenesis (GO:0061003)3.37505919
43regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.37320093
44dendritic spine morphogenesis (GO:0060997)3.37215386
45behavioral response to nicotine (GO:0035095)3.35326090
46positive regulation of synaptic transmission, GABAergic (GO:0032230)3.33233504
47dendrite morphogenesis (GO:0048813)3.32238096
48regulation of synaptic transmission, glutamatergic (GO:0051966)3.30533874
49regulation of synapse maturation (GO:0090128)3.27219493
50synapse assembly (GO:0007416)3.24316975
51negative regulation of cytosolic calcium ion concentration (GO:0051481)3.20656086
52membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.20047825
53proline transport (GO:0015824)3.16375058
54G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.16275913
55central nervous system projection neuron axonogenesis (GO:0021952)3.15781416
56cerebellar Purkinje cell differentiation (GO:0021702)3.15652719
57positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.15005863
58presynaptic membrane assembly (GO:0097105)3.14139947
59neuronal action potential propagation (GO:0019227)3.13965743
60behavioral defense response (GO:0002209)3.13951976
61behavioral fear response (GO:0001662)3.13951976
62synaptic vesicle endocytosis (GO:0048488)3.13347854
63cell migration in hindbrain (GO:0021535)3.12914812
64establishment of mitochondrion localization (GO:0051654)3.10941196
65regulation of excitatory postsynaptic membrane potential (GO:0060079)3.09619132
66membrane depolarization during action potential (GO:0086010)3.08744176
67regulation of dendritic spine morphogenesis (GO:0061001)3.08584816
68calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.07574251
69gamma-aminobutyric acid signaling pathway (GO:0007214)3.07023833
70detection of calcium ion (GO:0005513)3.06090920
71presynaptic membrane organization (GO:0097090)3.04778748
72regulation of postsynaptic membrane potential (GO:0060078)3.02989817
73gamma-aminobutyric acid transport (GO:0015812)3.01836957
74retinal cone cell development (GO:0046549)3.01757161
75mechanosensory behavior (GO:0007638)3.01714837
76regulation of vesicle fusion (GO:0031338)2.98936097
77transmission of nerve impulse (GO:0019226)2.98755478
78neurotransmitter transport (GO:0006836)2.98616229
79activation of protein kinase A activity (GO:0034199)2.98095971
80suckling behavior (GO:0001967)2.97670774
81regulation of neurotransmitter secretion (GO:0046928)2.97131193
82negative regulation of dendrite development (GO:2000171)2.96447167
83positive regulation of membrane potential (GO:0045838)2.96044683
84regulation of respiratory system process (GO:0044065)2.95737002
85long-term memory (GO:0007616)2.94692545
86neuronal ion channel clustering (GO:0045161)2.94364232
87positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.93987318
88protein localization to cilium (GO:0061512)2.93109582
89fear response (GO:0042596)2.91436526
90negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.91407033
91long-term synaptic potentiation (GO:0060291)2.88825082
92synapse organization (GO:0050808)2.88402522
93neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.87438989
94cell communication by electrical coupling (GO:0010644)2.86579289
95cochlea development (GO:0090102)2.86304256
96regulation of action potential (GO:0098900)2.85987889
97short-term memory (GO:0007614)2.85662909
98positive regulation of synapse assembly (GO:0051965)2.85106760
99cellular potassium ion homeostasis (GO:0030007)2.84850051
100regulation of synaptic plasticity (GO:0048167)2.84528124
101atrial cardiac muscle cell action potential (GO:0086014)2.83941589
102neural tube formation (GO:0001841)2.83763291
103striatum development (GO:0021756)2.82175624
104negative regulation of synaptic transmission, GABAergic (GO:0032229)2.81968545
105regulation of synaptic transmission, GABAergic (GO:0032228)2.80798832
106cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.80452384
107behavioral response to ethanol (GO:0048149)2.79856686
108auditory behavior (GO:0031223)2.79477700
109ganglion development (GO:0061548)2.79438637
110regulation of dendritic spine development (GO:0060998)2.78279446
111spinal cord development (GO:0021510)2.76767626
112positive regulation of dendritic spine development (GO:0060999)2.74421949
113regulation of neurotransmitter transport (GO:0051588)2.74063050
114membrane depolarization (GO:0051899)2.73360918
115pyrimidine nucleobase catabolic process (GO:0006208)2.72619177
116vesicle transport along microtubule (GO:0047496)2.70649677
117axonogenesis (GO:0007409)2.70380028
118regulation of axon extension involved in axon guidance (GO:0048841)2.70267385
119glycosphingolipid biosynthetic process (GO:0006688)2.70039390
120establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.69991356
121mitochondrion transport along microtubule (GO:0047497)2.69991356
122organelle transport along microtubule (GO:0072384)2.69931311
123regulation of neurotransmitter levels (GO:0001505)2.69585863
124regulation of axon guidance (GO:1902667)2.67325633
125* retinal ganglion cell axon guidance (GO:0031290)2.66654351
126inner ear receptor cell development (GO:0060119)2.66364553
127response to auditory stimulus (GO:0010996)2.66170436
128synaptic transmission (GO:0007268)2.65490551
129axon extension (GO:0048675)2.64172449
130startle response (GO:0001964)2.63503300
131regulation of calcium ion-dependent exocytosis (GO:0017158)2.62038654
132* homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.61972472
133cerebral cortex cell migration (GO:0021795)2.61936506
134membrane hyperpolarization (GO:0060081)2.61860269
135neuronal action potential (GO:0019228)2.55965407
136neuron migration (GO:0001764)2.52396807
137C4-dicarboxylate transport (GO:0015740)2.52244893
138adult walking behavior (GO:0007628)2.48151359
139substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.47159981

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.34966408
2GBX2_23144817_ChIP-Seq_PC3_Human4.02268785
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.95022842
4JARID2_20064375_ChIP-Seq_MESCs_Mouse2.85938813
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.77615951
6EZH2_27304074_Chip-Seq_ESCs_Mouse2.67605179
7* GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.58114625
8JARID2_20075857_ChIP-Seq_MESCs_Mouse2.55245994
9EZH2_18974828_ChIP-Seq_MESCs_Mouse2.54634237
10RNF2_18974828_ChIP-Seq_MESCs_Mouse2.54634237
11* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.48613776
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.47909198
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.46031874
14SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.43666463
15REST_21632747_ChIP-Seq_MESCs_Mouse2.37595022
16ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.35316705
17* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.28443803
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.27235305
19SALL1_21062744_ChIP-ChIP_HESCs_Human2.20930987
20* EZH2_27294783_Chip-Seq_ESCs_Mouse2.18966173
21CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.16904988
22HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.14145409
23* RNF2_27304074_Chip-Seq_ESCs_Mouse2.10167667
24SUZ12_27294783_Chip-Seq_ESCs_Mouse2.08636565
25DROSHA_22980978_ChIP-Seq_HELA_Human2.07384204
26CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02829535
27TAF15_26573619_Chip-Seq_HEK293_Human1.96924789
28* RARB_27405468_Chip-Seq_BRAIN_Mouse1.95124663
29NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.88698794
30* REST_18959480_ChIP-ChIP_MESCs_Mouse1.88338346
31BMI1_23680149_ChIP-Seq_NPCS_Mouse1.83997601
32* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.81655851
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80885034
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.79857209
35* SMAD4_21799915_ChIP-Seq_A2780_Human1.76045335
36* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.75259952
37RBPJ_22232070_ChIP-Seq_NCS_Mouse1.69830634
38CBX2_27304074_Chip-Seq_ESCs_Mouse1.69811718
39IGF1R_20145208_ChIP-Seq_DFB_Human1.69763640
40AR_21572438_ChIP-Seq_LNCaP_Human1.66770006
41PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.64863663
42* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.60251935
43* P300_19829295_ChIP-Seq_ESCs_Human1.55744188
44ZNF274_21170338_ChIP-Seq_K562_Hela1.54627811
45PIAS1_25552417_ChIP-Seq_VCAP_Human1.52954542
46POU3F2_20337985_ChIP-ChIP_501MEL_Human1.49253201
47* EWS_26573619_Chip-Seq_HEK293_Human1.48947599
48SMAD3_21741376_ChIP-Seq_EPCs_Human1.45381046
49NR3C1_23031785_ChIP-Seq_PC12_Mouse1.42151978
50RNF2_27304074_Chip-Seq_NSC_Mouse1.41633227
51SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39917103
52CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39899216
53* SOX2_21211035_ChIP-Seq_LN229_Gbm1.39364333
54* STAT3_23295773_ChIP-Seq_U87_Human1.38069084
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.37857784
56* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36781492
57* FUS_26573619_Chip-Seq_HEK293_Human1.35723786
58EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.34232265
59ER_23166858_ChIP-Seq_MCF-7_Human1.33927762
60AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.30870999
61CBP_20019798_ChIP-Seq_JUKART_Human1.29738418
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.29738418
63* PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.29723301
64IKZF1_21737484_ChIP-ChIP_HCT116_Human1.29455517
65* RING1B_27294783_Chip-Seq_ESCs_Mouse1.29214131
66AR_25329375_ChIP-Seq_VCAP_Human1.27483641
67RING1B_27294783_Chip-Seq_NPCs_Mouse1.25689271
68FLI1_27457419_Chip-Seq_LIVER_Mouse1.22711446
69* AR_19668381_ChIP-Seq_PC3_Human1.22563997
70ZNF217_24962896_ChIP-Seq_MCF-7_Human1.22262203
71* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.21066733
72* TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.19708040
73LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19509812
74* TCF4_23295773_ChIP-Seq_U87_Human1.18871149
75GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18622974
76STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.18075326
77* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.16976573
78* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.16930073
79* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.16357086
80* ARNT_22903824_ChIP-Seq_MCF-7_Human1.16067069
81BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.15647753
82TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14096723
83AHR_22903824_ChIP-Seq_MCF-7_Human1.13901678
84VDR_22108803_ChIP-Seq_LS180_Human1.13762641
85P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13621386
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.13558996
87ERG_21242973_ChIP-ChIP_JURKAT_Human1.12066343
88NR3C1_21868756_ChIP-Seq_MCF10A_Human1.11215549
89KDM2B_26808549_Chip-Seq_REH_Human1.10453658
90TCF4_18268006_ChIP-ChIP_LS174T_Human1.10445767
91TAL1_26923725_Chip-Seq_HPCs_Mouse1.10084934
92MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09185723
93FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.09176066
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09101839
95P53_22387025_ChIP-Seq_ESCs_Mouse1.08778510
96SOX9_26525672_Chip-Seq_HEART_Mouse1.07966565
97* TCF4_22108803_ChIP-Seq_LS180_Human1.07523760
98* RUNX2_22187159_ChIP-Seq_PCA_Human1.06910122
99SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05220482
100TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.05196460
101TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04905634
102POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.04905634
103PCGF2_27294783_Chip-Seq_ESCs_Mouse1.04642128
104SMAD_19615063_ChIP-ChIP_OVARY_Human1.03310552
105* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.02454642
106TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01808131
107E2F1_18555785_Chip-Seq_ESCs_Mouse1.00201258
108* SMAD3_21741376_ChIP-Seq_ESCs_Human1.00153382
109NANOG_18555785_Chip-Seq_ESCs_Mouse0.99576978
110CDX2_19796622_ChIP-Seq_MESCs_Mouse0.98775841
111* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.98430746
112MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.98264204
113RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.97843206
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.95744508
115TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95469280
116OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.93984015
117PRDM14_20953172_ChIP-Seq_ESCs_Human0.93193451
118TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92168294
119SMAD4_21741376_ChIP-Seq_HESCs_Human0.91754250
120BCAT_22108803_ChIP-Seq_LS180_Human0.91649122
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90936068
122* ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.90678292

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.14802678
2MP0003880_abnormal_central_pattern4.06092081
3MP0003635_abnormal_synaptic_transmissio3.38910183
4MP0004270_analgesia3.18975934
5MP0002063_abnormal_learning/memory/cond2.85339533
6MP0001968_abnormal_touch/_nociception2.78508073
7MP0002735_abnormal_chemical_nociception2.61128822
8MP0009745_abnormal_behavioral_response2.58418178
9MP0002736_abnormal_nociception_after2.43061040
10MP0002572_abnormal_emotion/affect_behav2.42913445
11MP0002064_seizures2.40172619
12MP0005423_abnormal_somatic_nervous2.38537191
13MP0002734_abnormal_mechanical_nocicepti2.36367516
14MP0009046_muscle_twitch2.23388755
15MP0002184_abnormal_innervation2.14821830
16MP0000778_abnormal_nervous_system2.12043794
17MP0003122_maternal_imprinting2.10674951
18MP0001486_abnormal_startle_reflex2.08514847
19MP0002272_abnormal_nervous_system2.08256291
20MP0002909_abnormal_adrenal_gland2.05420341
21MP0009780_abnormal_chondrocyte_physiolo2.04306716
22MP0001984_abnormal_olfaction2.02174594
23MP0003787_abnormal_imprinting1.96453312
24MP0002733_abnormal_thermal_nociception1.89649835
25MP0006276_abnormal_autonomic_nervous1.86374477
26MP0002067_abnormal_sensory_capabilities1.80643284
27* MP0000955_abnormal_spinal_cord1.78682336
28MP0002557_abnormal_social/conspecific_i1.75534094
29MP0001970_abnormal_pain_threshold1.74889677
30MP0001501_abnormal_sleep_pattern1.74692723
31MP0002822_catalepsy1.72272643
32MP0000013_abnormal_adipose_tissue1.66217246
33MP0004811_abnormal_neuron_physiology1.65281435
34MP0001440_abnormal_grooming_behavior1.62559493
35MP0005645_abnormal_hypothalamus_physiol1.59344241
36MP0005646_abnormal_pituitary_gland1.57110837
37MP0010386_abnormal_urinary_bladder1.56924180
38MP0001188_hyperpigmentation1.56462485
39MP0004924_abnormal_behavior1.45888474
40MP0005386_behavior/neurological_phenoty1.45888474
41* MP0002882_abnormal_neuron_morphology1.45651280
42MP0003890_abnormal_embryonic-extraembry1.39705821
43MP0004858_abnormal_nervous_system1.38105637
44MP0000631_abnormal_neuroendocrine_gland1.33512465
45MP0002102_abnormal_ear_morphology1.32095247
46MP0001502_abnormal_circadian_rhythm1.29384036
47MP0003879_abnormal_hair_cell1.27804064
48MP0003283_abnormal_digestive_organ1.27092491
49MP0006072_abnormal_retinal_apoptosis1.25443687
50MP0000569_abnormal_digit_pigmentation1.25325702
51MP0005551_abnormal_eye_electrophysiolog1.23965050
52MP0003011_delayed_dark_adaptation1.23938101
53MP0003121_genomic_imprinting1.23063621
54MP0008569_lethality_at_weaning1.21347738
55MP0002066_abnormal_motor_capabilities/c1.19910571
56MP0004885_abnormal_endolymph1.18902979
57MP0005394_taste/olfaction_phenotype1.18135045
58MP0005499_abnormal_olfactory_system1.18135045
59MP0001529_abnormal_vocalization1.16300615
60MP0002234_abnormal_pharynx_morphology1.13701799
61* MP0002152_abnormal_brain_morphology1.11503716
62MP0003942_abnormal_urinary_system1.11472290
63MP0004142_abnormal_muscle_tone1.10450468
64MP0005409_darkened_coat_color1.10001034
65MP0005248_abnormal_Harderian_gland1.08775348
66MP0008877_abnormal_DNA_methylation1.05434688
67MP0001299_abnormal_eye_distance/1.02080819
68MP0003329_amyloid_beta_deposits1.01010759
69MP0002837_dystrophic_cardiac_calcinosis0.99336045
70MP0003183_abnormal_peptide_metabolism0.98000809
71MP0002638_abnormal_pupillary_reflex0.97981377
72MP0005187_abnormal_penis_morphology0.97462193
73MP0002752_abnormal_somatic_nervous0.96888707
74MP0003123_paternal_imprinting0.96827135
75MP0000678_abnormal_parathyroid_gland0.96173362
76MP0001485_abnormal_pinna_reflex0.96046589
77MP0002938_white_spotting0.94093174
78MP0001986_abnormal_taste_sensitivity0.94026225
79MP0004133_heterotaxia0.92997926
80MP0002751_abnormal_autonomic_nervous0.92633292
81MP0002069_abnormal_eating/drinking_beha0.91338435
82MP0008789_abnormal_olfactory_epithelium0.89797102
83MP0005195_abnormal_posterior_eye0.88942915
84MP0004085_abnormal_heartbeat0.88529198
85* MP0000534_abnormal_ureter_morphology0.88129540
86MP0003195_calcinosis0.86285200
87MP0003136_yellow_coat_color0.85471137
88MP0004233_abnormal_muscle_weight0.84604525
89* MP0003861_abnormal_nervous_system0.84289266
90MP0008961_abnormal_basal_metabolism0.84135436
91MP0006292_abnormal_olfactory_placode0.82548882
92MP0004043_abnormal_pH_regulation0.82528926
93MP0005379_endocrine/exocrine_gland_phen0.81625281
94MP0001963_abnormal_hearing_physiology0.80349200
95MP0004145_abnormal_muscle_electrophysio0.79816443
96MP0003755_abnormal_palate_morphology0.78587735
97MP0002229_neurodegeneration0.78172109
98MP0005253_abnormal_eye_physiology0.77932673
99MP0003633_abnormal_nervous_system0.77908124
100MP0004742_abnormal_vestibular_system0.77734517
101MP0001944_abnormal_pancreas_morphology0.75880262
102MP0000566_synostosis0.75747098
103MP0001177_atelectasis0.75689657
104MP0003119_abnormal_digestive_system0.74110134
105MP0003937_abnormal_limbs/digits/tail_de0.73443507
106MP0002090_abnormal_vision0.73286274
107MP0000049_abnormal_middle_ear0.73037038
108MP0000647_abnormal_sebaceous_gland0.71858639
109MP0003634_abnormal_glial_cell0.71740328
110MP0000003_abnormal_adipose_tissue0.71569260
111MP0001905_abnormal_dopamine_level0.71186202
112MP0005174_abnormal_tail_pigmentation0.71122958
113MP0002233_abnormal_nose_morphology0.69448243
114MP0003385_abnormal_body_wall0.66295641
115MP0000026_abnormal_inner_ear0.66111418
116MP0003631_nervous_system_phenotype0.66110809
117MP0002876_abnormal_thyroid_physiology0.65946222
118MP0002653_abnormal_ependyma_morphology0.65243313
119MP0002163_abnormal_gland_morphology0.65180074

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.47317271
2Epileptic encephalopathy (HP:0200134)4.37491304
3Focal seizures (HP:0007359)4.18658388
4Myokymia (HP:0002411)4.05471853
5Febrile seizures (HP:0002373)3.95817630
6Visual hallucinations (HP:0002367)3.75979949
7Intestinal atresia (HP:0011100)3.62384419
8Atonic seizures (HP:0010819)3.61509463
9Absence seizures (HP:0002121)3.39451467
10Progressive cerebellar ataxia (HP:0002073)3.37616806
11Hepatoblastoma (HP:0002884)3.27131265
12Generalized tonic-clonic seizures (HP:0002069)3.05796420
13Abnormality of the labia minora (HP:0012880)3.04712655
14Epileptiform EEG discharges (HP:0011182)3.01539296
15Dialeptic seizures (HP:0011146)2.98906565
16EEG with generalized epileptiform discharges (HP:0011198)2.96509995
17Hypoventilation (HP:0002791)2.93348529
18Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.81990489
19Limb dystonia (HP:0002451)2.80457538
20Drooling (HP:0002307)2.77776710
21Excessive salivation (HP:0003781)2.77776710
22Hypsarrhythmia (HP:0002521)2.73286988
23Hyperventilation (HP:0002883)2.73180411
24Supranuclear gaze palsy (HP:0000605)2.63945503
25Pachygyria (HP:0001302)2.63597273
26Broad-based gait (HP:0002136)2.60719071
27Amblyopia (HP:0000646)2.60370725
28Agitation (HP:0000713)2.54610269
29Ankle clonus (HP:0011448)2.52079225
30Poor eye contact (HP:0000817)2.47891933
31Absent speech (HP:0001344)2.36298746
32Gait imbalance (HP:0002141)2.35209758
33Pheochromocytoma (HP:0002666)2.32563190
34Depression (HP:0000716)2.32190625
35Shoulder girdle muscle weakness (HP:0003547)2.31520040
36Blue irides (HP:0000635)2.31434352
37Action tremor (HP:0002345)2.30605456
38Split foot (HP:0001839)2.29849121
39True hermaphroditism (HP:0010459)2.26215712
40Truncal ataxia (HP:0002078)2.25839596
41Pancreatic fibrosis (HP:0100732)2.25251811
42Megalencephaly (HP:0001355)2.25160690
43Abnormal eating behavior (HP:0100738)2.23756617
44Hemiparesis (HP:0001269)2.22480961
45Impaired social interactions (HP:0000735)2.19582945
46Abnormal social behavior (HP:0012433)2.19582945
47Papilledema (HP:0001085)2.19205573
48Nephronophthisis (HP:0000090)2.18889238
49Pancreatic cysts (HP:0001737)2.17944272
50Genetic anticipation (HP:0003743)2.17905447
51Type II lissencephaly (HP:0007260)2.17186759
52Narrow forehead (HP:0000341)2.17148428
53Abnormality of midbrain morphology (HP:0002418)2.13700673
54Molar tooth sign on MRI (HP:0002419)2.13700673
55Gastrointestinal atresia (HP:0002589)2.13321260
56Impaired vibration sensation in the lower limbs (HP:0002166)2.12990942
57Gaze-evoked nystagmus (HP:0000640)2.12647757
58Postaxial hand polydactyly (HP:0001162)2.08609833
59Neoplasm of the heart (HP:0100544)2.07162465
60Anxiety (HP:0000739)2.06337176
61Protruding tongue (HP:0010808)2.05256319
62Insidious onset (HP:0003587)2.04989328
63Termporal pattern (HP:0011008)2.04989328
64Retinal dysplasia (HP:0007973)2.04939543
65Lissencephaly (HP:0001339)2.03281791
66Polyphagia (HP:0002591)2.01629364
67Neuroendocrine neoplasm (HP:0100634)2.00827325
68Volvulus (HP:0002580)1.99721473
69Urinary bladder sphincter dysfunction (HP:0002839)1.99462673
70Hypoplasia of the brainstem (HP:0002365)1.98462276
71Aplasia/Hypoplasia of the brainstem (HP:0007362)1.98462276
72Torticollis (HP:0000473)1.96282476
73Abnormality of calcium-phosphate metabolism (HP:0100530)1.95883101
74Exotropia (HP:0000577)1.95555662
75Aplasia/Hypoplasia of the sternum (HP:0006714)1.94063854
76Mutism (HP:0002300)1.93721305
77Genital tract atresia (HP:0001827)1.92912437
78Oligodactyly (hands) (HP:0001180)1.89702830
79Epidermoid cyst (HP:0200040)1.88602576
80Inability to walk (HP:0002540)1.88580134
81Vaginal atresia (HP:0000148)1.88158810
82Failure to thrive in infancy (HP:0001531)1.88007017
83Esotropia (HP:0000565)1.86721578
84Abnormality of salivation (HP:0100755)1.86100747
85Dysdiadochokinesis (HP:0002075)1.85579711
86Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.84386980
87Short 4th metacarpal (HP:0010044)1.84386980
88Congenital stationary night blindness (HP:0007642)1.84349545
89Stereotypic behavior (HP:0000733)1.84172450
90Aqueductal stenosis (HP:0002410)1.82960458
91Labial hypoplasia (HP:0000066)1.82697682
92Abnormality of the lower motor neuron (HP:0002366)1.81662928
93Abnormality of the renal medulla (HP:0100957)1.80786580
94Poor coordination (HP:0002370)1.80541323
95Congenital primary aphakia (HP:0007707)1.78328542
96Alacrima (HP:0000522)1.78309513
97Medial flaring of the eyebrow (HP:0010747)1.77121488
98Cerebral inclusion bodies (HP:0100314)1.76482831
99Fair hair (HP:0002286)1.76204627
100Abnormality of the corticospinal tract (HP:0002492)1.75895488
101Downturned corners of mouth (HP:0002714)1.75574568
102Spastic gait (HP:0002064)1.75513070
103Impaired smooth pursuit (HP:0007772)1.74329726
104Growth hormone deficiency (HP:0000824)1.73827410
105Cutaneous syndactyly (HP:0012725)1.73641290
106Tubulointerstitial nephritis (HP:0001970)1.73513123
107Cutaneous finger syndactyly (HP:0010554)1.73449390
108Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.73358129
109Short foot (HP:0001773)1.73186367
110* Renal hypoplasia (HP:0000089)1.72961342
111Status epilepticus (HP:0002133)1.72892181
112Optic nerve hypoplasia (HP:0000609)1.72853869
113Gastroesophageal reflux (HP:0002020)1.72533061
114Focal dystonia (HP:0004373)1.71901083
115Thyroid carcinoma (HP:0002890)1.71710401
116Amyotrophic lateral sclerosis (HP:0007354)1.71347836
117Nephrogenic diabetes insipidus (HP:0009806)1.71095668
118Bony spicule pigmentary retinopathy (HP:0007737)1.70704116
119Central scotoma (HP:0000603)1.70313234
120Urinary urgency (HP:0000012)1.69762490
121Sclerocornea (HP:0000647)1.68941918
122Neurofibrillary tangles (HP:0002185)1.68736185
123Fetal akinesia sequence (HP:0001989)1.68596570
124Papillary thyroid carcinoma (HP:0002895)1.67597526
125Tented upper lip vermilion (HP:0010804)1.67030978
126Hyperthyroidism (HP:0000836)1.66066037
127Hypothermia (HP:0002045)1.65922004
128Chronic hepatic failure (HP:0100626)1.65864592
129Cupped ear (HP:0000378)1.65346897
130Macroglossia (HP:0000158)1.65228806
131Inappropriate behavior (HP:0000719)1.64797490
132Postural instability (HP:0002172)1.64786699
133Bradykinesia (HP:0002067)1.64694738
134Abnormality of macular pigmentation (HP:0008002)1.63915214
135Decreased lacrimation (HP:0000633)1.63699811
136Scrotal hypoplasia (HP:0000046)1.63573496
137Specific learning disability (HP:0001328)1.63068812
138Open mouth (HP:0000194)1.62557648
139Neoplasm of the adrenal cortex (HP:0100641)1.62456376
140Hypoplasia of the corpus callosum (HP:0002079)1.62337534
141Methylmalonic acidemia (HP:0002912)1.61233047
142Insomnia (HP:0100785)1.60976368
143Dysmetria (HP:0001310)1.60263650
144Absent eyebrow (HP:0002223)1.60092446
145Midline defect of the nose (HP:0004122)1.59562622
146Autism (HP:0000717)1.59109172
147Akinesia (HP:0002304)1.58654840
148Hypoplastic female external genitalia (HP:0012815)1.57386142
149Progressive inability to walk (HP:0002505)1.57355522

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.62079980
2EPHA44.12283245
3NTRK33.99029584
4MAP3K42.84689731
5MAP3K92.79812954
6CASK2.66401972
7MAP2K72.43344272
8MINK12.35339610
9PRKD32.23791461
10NTRK22.00298017
11MAPK131.96585541
12MAP4K21.94991057
13PAK61.88712436
14DAPK21.87232532
15PRPF4B1.77209220
16INSRR1.70667893
17KSR11.63788411
18NTRK11.63277984
19WNK31.55602945
20PLK21.52524594
21KSR21.52023558
22MAP3K21.46140481
23UHMK11.45134255
24MKNK21.43876944
25ERBB31.43866501
26CDK51.38416981
27SIK21.37705923
28EPHA31.37609976
29MAP2K41.34863316
30PHKG21.33553871
31PHKG11.33553871
32CAMKK11.25886075
33GRK11.22622348
34AKT31.19854607
35TNIK1.19573278
36FGFR31.19191325
37CSNK1G11.13269632
38BMPR1B1.09560339
39GRK51.09475193
40PRKCG1.08494365
41PAK31.08146734
42DAPK11.05828472
43SGK2231.02425636
44SGK4941.02425636
45CAMKK21.00622524
46CSNK1G20.97815358
47SGK20.97047716
48DYRK1A0.96843082
49LATS20.92973487
50CAMK2A0.91652146
51ADRBK20.91304905
52FRK0.89582777
53DYRK20.86300813
54PRKCE0.84520636
55TAF10.83483060
56MARK20.82185192
57RIPK40.82069334
58RET0.80738704
59PRKCH0.80187216
60PNCK0.79257840
61CDK140.79059358
62STK38L0.78839232
63STK380.78234271
64CAMK2B0.76550423
65CDK180.74824231
66SGK10.73374891
67RPS6KA20.72649146
68FER0.72336188
69WNK40.72118245
70CDK150.71681973
71BCR0.66849688
72CCNB10.66665997
73CAMK1G0.65936617
74TRIM280.65034213
75BMPR20.62881708
76SGK30.62338878
77WNK10.61970895
78PRKCZ0.61536004
79MAP3K120.60628853
80CDK11A0.60071679
81CAMK40.59919161
82NUAK10.59612527
83CSNK1D0.58197449
84PASK0.57638960
85CSNK1E0.55598252
86CAMK1D0.55372187
87CAMK2D0.54827723
88MAPK150.54530075
89PRKACA0.53387451
90MAP2K10.52672727
91FES0.51535026
92CDK30.51019679
93CAMK10.50304658
94EPHB20.50158502
95PRKG10.49832675
96RPS6KA30.49242261
97FGFR20.48737800
98CDC42BPA0.48589262
99HIPK20.47933963
100MKNK10.47892709
101CSNK1A10.47696048
102PDGFRA0.47238662
103STK390.47081442
104STK160.46317792
105STK110.46264060
106ADRBK10.45412336
107ERBB20.45237471
108LATS10.45218651
109TAOK20.44603360
110SIK30.44153804
111PRKCB0.42928652
112PINK10.42820136
113CSNK1G30.42754930
114MAP3K60.41105246
115MAPK100.39747292
116SCYL20.39166636
117OXSR10.39066799
118TYRO30.38799235
119CSNK1A1L0.38576961
120PRKACB0.38018651
121ACVR1B0.37688938
122BRAF0.37333875
123ROCK10.37172018
124ARAF0.36894188
125GSK3B0.36815106
126PKN10.35612120
127MAP3K10.35330682
128MAPK90.35286124
129PRKDC0.33680271
130PRKACG0.32615302
131DYRK1B0.31259601
132STK30.31162913
133YES10.30511284
134MAPK80.29552826

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.57040497
2Synaptic vesicle cycle_Homo sapiens_hsa047213.00190710
3GABAergic synapse_Homo sapiens_hsa047272.74984457
4Circadian entrainment_Homo sapiens_hsa047132.64818045
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.64233456
6Morphine addiction_Homo sapiens_hsa050322.48683547
7Insulin secretion_Homo sapiens_hsa049112.47183218
8Glutamatergic synapse_Homo sapiens_hsa047242.45321872
9Long-term potentiation_Homo sapiens_hsa047202.44517475
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.40368932
11Amphetamine addiction_Homo sapiens_hsa050312.39855281
12Olfactory transduction_Homo sapiens_hsa047402.32207367
13Dopaminergic synapse_Homo sapiens_hsa047282.24639501
14Cocaine addiction_Homo sapiens_hsa050302.03808188
15Taste transduction_Homo sapiens_hsa047421.99570380
16Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.99474138
17Butanoate metabolism_Homo sapiens_hsa006501.91013297
18Cholinergic synapse_Homo sapiens_hsa047251.90319627
19Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.87944605
20Serotonergic synapse_Homo sapiens_hsa047261.75464545
21Salivary secretion_Homo sapiens_hsa049701.75254092
22Renin secretion_Homo sapiens_hsa049241.71913677
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.67935431
24Long-term depression_Homo sapiens_hsa047301.65439211
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.51037434
26Type II diabetes mellitus_Homo sapiens_hsa049301.50295500
27* Axon guidance_Homo sapiens_hsa043601.49142017
28Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48716484
29Vibrio cholerae infection_Homo sapiens_hsa051101.47519268
30Oxytocin signaling pathway_Homo sapiens_hsa049211.43703825
31Collecting duct acid secretion_Homo sapiens_hsa049661.38097696
32Gastric acid secretion_Homo sapiens_hsa049711.37167921
33Calcium signaling pathway_Homo sapiens_hsa040201.34041411
34Propanoate metabolism_Homo sapiens_hsa006401.31598621
35Gap junction_Homo sapiens_hsa045401.31032316
36Maturity onset diabetes of the young_Homo sapiens_hsa049501.25894070
37Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20486216
38cAMP signaling pathway_Homo sapiens_hsa040241.20038033
39GnRH signaling pathway_Homo sapiens_hsa049121.18202534
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.13586052
41Estrogen signaling pathway_Homo sapiens_hsa049151.09392166
42cGMP-PKG signaling pathway_Homo sapiens_hsa040221.08580667
43Ether lipid metabolism_Homo sapiens_hsa005651.04114611
44Melanogenesis_Homo sapiens_hsa049161.03196263
45Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.01678873
46ErbB signaling pathway_Homo sapiens_hsa040121.00083991
47Glioma_Homo sapiens_hsa052140.98199572
48Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.96402237
49Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93086134
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.92511894
51Basal transcription factors_Homo sapiens_hsa030220.90235778
52Phototransduction_Homo sapiens_hsa047440.87080063
53Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.86935535
54Alcoholism_Homo sapiens_hsa050340.85887807
55Endometrial cancer_Homo sapiens_hsa052130.85341484
56Oocyte meiosis_Homo sapiens_hsa041140.84679843
57Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.84600187
58Basal cell carcinoma_Homo sapiens_hsa052170.83147971
59beta-Alanine metabolism_Homo sapiens_hsa004100.82035417
60Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.81555998
61Carbohydrate digestion and absorption_Homo sapiens_hsa049730.81124510
62Steroid biosynthesis_Homo sapiens_hsa001000.80732117
63Pancreatic secretion_Homo sapiens_hsa049720.79623925
64Type I diabetes mellitus_Homo sapiens_hsa049400.78385882
65Dilated cardiomyopathy_Homo sapiens_hsa054140.76935000
66Circadian rhythm_Homo sapiens_hsa047100.75764277
67Glucagon signaling pathway_Homo sapiens_hsa049220.75306254
68Thyroid hormone synthesis_Homo sapiens_hsa049180.74103341
69Linoleic acid metabolism_Homo sapiens_hsa005910.73017371
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.72277264
71Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71805645
72Nitrogen metabolism_Homo sapiens_hsa009100.71172683
73Cardiac muscle contraction_Homo sapiens_hsa042600.68600143
74Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.68495263
75Dorso-ventral axis formation_Homo sapiens_hsa043200.66744986
76MAPK signaling pathway_Homo sapiens_hsa040100.66622367
77Wnt signaling pathway_Homo sapiens_hsa043100.65994829
78Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.64483473
79mTOR signaling pathway_Homo sapiens_hsa041500.64250780
80Tryptophan metabolism_Homo sapiens_hsa003800.64226630
81Phospholipase D signaling pathway_Homo sapiens_hsa040720.63933461
82ABC transporters_Homo sapiens_hsa020100.63556568
83alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.62868443
84Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.62390774
85Thyroid hormone signaling pathway_Homo sapiens_hsa049190.62045355
86Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61622151
87Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.60733996
88Choline metabolism in cancer_Homo sapiens_hsa052310.60507670
89Ras signaling pathway_Homo sapiens_hsa040140.60279961
90Vitamin B6 metabolism_Homo sapiens_hsa007500.59581018
91Hedgehog signaling pathway_Homo sapiens_hsa043400.59481352
92Neurotrophin signaling pathway_Homo sapiens_hsa047220.58109791
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.58089153
94Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57404939
95Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.56499265
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.55365042
97Renal cell carcinoma_Homo sapiens_hsa052110.54427142
98Longevity regulating pathway - mammal_Homo sapiens_hsa042110.54404189
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.54036214
100Insulin signaling pathway_Homo sapiens_hsa049100.53981784
101Rap1 signaling pathway_Homo sapiens_hsa040150.52783943
102Colorectal cancer_Homo sapiens_hsa052100.52051233
103Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50109817
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47784647
105Glycerolipid metabolism_Homo sapiens_hsa005610.46570212
106Caffeine metabolism_Homo sapiens_hsa002320.43887601
107Oxidative phosphorylation_Homo sapiens_hsa001900.43254975
108Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.43253681
109Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.42855327
110Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.42766136
111Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.42348943
112Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.42253074
113Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.41636256
114Non-small cell lung cancer_Homo sapiens_hsa052230.39933226
115Central carbon metabolism in cancer_Homo sapiens_hsa052300.39682982
116Protein export_Homo sapiens_hsa030600.39447027
117Inositol phosphate metabolism_Homo sapiens_hsa005620.39400423
118Prion diseases_Homo sapiens_hsa050200.38755799
119Retinol metabolism_Homo sapiens_hsa008300.38103224
120Melanoma_Homo sapiens_hsa052180.37810701
121VEGF signaling pathway_Homo sapiens_hsa043700.37315203
122Ovarian steroidogenesis_Homo sapiens_hsa049130.37247155
123Prolactin signaling pathway_Homo sapiens_hsa049170.34922822
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.33292672
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32420332
126Regulation of autophagy_Homo sapiens_hsa041400.32318786
127Hippo signaling pathway_Homo sapiens_hsa043900.32062581
128Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.31984390

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »