RPA2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proline biosynthetic process (GO:0006561)6.55055356
2DNA deamination (GO:0045006)6.47826037
3replication fork processing (GO:0031297)5.93934936
4transcription from mitochondrial promoter (GO:0006390)5.60882986
5maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)5.51820185
6somatic hypermutation of immunoglobulin genes (GO:0016446)5.22808542
7somatic diversification of immune receptors via somatic mutation (GO:0002566)5.22808542
8* telomere maintenance via semi-conservative replication (GO:0032201)5.13436999
9* DNA strand elongation involved in DNA replication (GO:0006271)5.13155897
10* DNA strand elongation (GO:0022616)4.85744388
11formation of translation preinitiation complex (GO:0001731)4.82477501
12proline metabolic process (GO:0006560)4.81967064
13viral mRNA export from host cell nucleus (GO:0046784)4.76160466
14embryonic process involved in female pregnancy (GO:0060136)4.57544100
15DNA strand renaturation (GO:0000733)4.46168869
16DNA replication initiation (GO:0006270)4.43213102
17* telomere maintenance via recombination (GO:0000722)4.37913188
18negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.30993133
19mitochondrial DNA metabolic process (GO:0032042)4.29469029
20chromatin remodeling at centromere (GO:0031055)4.19476889
21CENP-A containing nucleosome assembly (GO:0034080)4.17480088
22DNA unwinding involved in DNA replication (GO:0006268)4.07528840
23regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.07342739
24kinetochore assembly (GO:0051382)4.06528520
25meiotic chromosome segregation (GO:0045132)4.06351010
26negative regulation of mRNA splicing, via spliceosome (GO:0048025)4.05376433
27* nucleotide-excision repair, DNA gap filling (GO:0006297)4.02588535
28* mitotic recombination (GO:0006312)4.00591183
29positive regulation of protein homooligomerization (GO:0032464)3.99497555
30mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.99246793
31positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.94825646
32DNA replication checkpoint (GO:0000076)3.91827723
33anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.90957544
34negative regulation of ligase activity (GO:0051352)3.90714736
35negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.90714736
36kinetochore organization (GO:0051383)3.88727967
37* telomere maintenance via telomere lengthening (GO:0010833)3.82913438
38oxidative demethylation (GO:0070989)3.75049346
39termination of RNA polymerase II transcription (GO:0006369)3.74028817
40* base-excision repair (GO:0006284)3.73206352
41DNA catabolic process, exonucleolytic (GO:0000738)3.70839054
42signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.68227990
43signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.68227990
44signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.68227990
45establishment of integrated proviral latency (GO:0075713)3.67311840
46DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.67051291
47DNA double-strand break processing (GO:0000729)3.65106685
48histone exchange (GO:0043486)3.64551693
49maturation of 5.8S rRNA (GO:0000460)3.63909267
50intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.63098557
51signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.63098557
52mRNA cleavage (GO:0006379)3.60514959
53establishment of apical/basal cell polarity (GO:0035089)3.60178969
54protein K6-linked ubiquitination (GO:0085020)3.60112909
55negative regulation of mRNA processing (GO:0050686)3.58707889
56poly(A)+ mRNA export from nucleus (GO:0016973)3.56809351
57signal transduction involved in DNA damage checkpoint (GO:0072422)3.56242550
58signal transduction involved in DNA integrity checkpoint (GO:0072401)3.56242550
59non-recombinational repair (GO:0000726)3.54740201
60double-strand break repair via nonhomologous end joining (GO:0006303)3.54740201
61energy coupled proton transport, down electrochemical gradient (GO:0015985)3.53612410
62ATP synthesis coupled proton transport (GO:0015986)3.53612410
63pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.53580129
64signal transduction involved in cell cycle checkpoint (GO:0072395)3.52676766
65regulation of cellular amino acid metabolic process (GO:0006521)3.52656345
66establishment of protein localization to mitochondrial membrane (GO:0090151)3.51086091
67ribosome biogenesis (GO:0042254)3.50389211
68DNA topological change (GO:0006265)3.47866327
69DNA ligation (GO:0006266)3.47860978
70mitotic sister chromatid segregation (GO:0000070)3.47135397
71negative regulation of RNA splicing (GO:0033119)3.44936793
72positive regulation of mitotic sister chromatid separation (GO:1901970)3.44709027
73positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.44709027
74positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.44709027
75positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.43874969
76mitochondrial RNA metabolic process (GO:0000959)3.43125931
77regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.41480005
78spliceosomal complex assembly (GO:0000245)3.39580599
79positive regulation of chromosome segregation (GO:0051984)3.39553883
80base-excision repair, AP site formation (GO:0006285)3.38478200
81mitotic chromosome condensation (GO:0007076)3.37550772
82spliceosomal tri-snRNP complex assembly (GO:0000244)3.37107267
83positive regulation of ligase activity (GO:0051351)3.36533723
84dosage compensation (GO:0007549)3.36366516
85lactate metabolic process (GO:0006089)3.36344773
86regulation of translational fidelity (GO:0006450)3.35554795
87histone mRNA metabolic process (GO:0008334)3.34383047
88regulation of sister chromatid cohesion (GO:0007063)3.32813999
89regulation of integrin activation (GO:0033623)3.32771066
90mitotic nuclear envelope disassembly (GO:0007077)3.32377213
91deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.32345086
92nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31668091
93nucleobase biosynthetic process (GO:0046112)3.29460486
94exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.28069561
95DNA replication-dependent nucleosome assembly (GO:0006335)3.27322523
96DNA replication-dependent nucleosome organization (GO:0034723)3.27322523
97DNA integration (GO:0015074)3.25509900
98spliceosomal snRNP assembly (GO:0000387)3.24115113
99regulation of protein homooligomerization (GO:0032462)3.22619965
100pseudouridine synthesis (GO:0001522)3.22258469
101DNA replication-independent nucleosome assembly (GO:0006336)3.21561778
102DNA replication-independent nucleosome organization (GO:0034724)3.21561778
103* cell cycle G1/S phase transition (GO:0044843)3.21321866
104* G1/S transition of mitotic cell cycle (GO:0000082)3.21321866
105negative regulation of DNA-dependent DNA replication (GO:2000104)3.17424639
106resolution of meiotic recombination intermediates (GO:0000712)3.16972645
107protein localization to kinetochore (GO:0034501)3.15449433
108regulation of ubiquitin-protein transferase activity (GO:0051438)3.15274027
109negative regulation of cell cycle arrest (GO:0071157)3.15126967
110mitochondrial DNA replication (GO:0006264)3.14069571
111rRNA processing (GO:0006364)3.13977055
112cullin deneddylation (GO:0010388)3.13550150
113oxidative phosphorylation (GO:0006119)3.12889047
114rRNA modification (GO:0000154)3.12214446
115regulation of ligase activity (GO:0051340)3.10367030
116mitotic metaphase plate congression (GO:0007080)3.08872410
117mRNA export from nucleus (GO:0006406)3.06161014
118tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.05626822
119RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.05626822
120DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.05499458
121antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.03927711
122proteasome assembly (GO:0043248)3.03651663
123nuclear envelope disassembly (GO:0051081)3.03545453
124membrane disassembly (GO:0030397)3.03545453
125ribonucleoprotein complex biogenesis (GO:0022613)3.03020405
126establishment of monopolar cell polarity (GO:0061162)3.02826770
127establishment or maintenance of monopolar cell polarity (GO:0061339)3.02826770
128rRNA metabolic process (GO:0016072)3.02585176
129histone H4-K12 acetylation (GO:0043983)3.02368712
130IMP biosynthetic process (GO:0006188)3.01495676
131regulation of helicase activity (GO:0051095)3.01417409
132regulation of gene silencing by RNA (GO:0060966)3.01335145
133regulation of posttranscriptional gene silencing (GO:0060147)3.01335145
134regulation of gene silencing by miRNA (GO:0060964)3.01335145
135DNA duplex unwinding (GO:0032508)3.00846285
136DNA geometric change (GO:0032392)2.99584035
137translational initiation (GO:0006413)2.99420195
138regulation of mitochondrial translation (GO:0070129)2.98944636
139* mismatch repair (GO:0006298)2.98737128
140purine nucleobase biosynthetic process (GO:0009113)2.98514127
141establishment of viral latency (GO:0019043)2.96987742
142RNA export from nucleus (GO:0006405)2.96339936
143sister chromatid segregation (GO:0000819)2.95551404
144postreplication repair (GO:0006301)2.94292237
145negative regulation of chromosome segregation (GO:0051985)2.94185845
146maturation of SSU-rRNA (GO:0030490)2.93253200
147viral transcription (GO:0019083)2.92092255
148protein deneddylation (GO:0000338)2.91680697
149ribosome assembly (GO:0042255)2.90628695
150regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.89665333
151regulation of mitotic spindle checkpoint (GO:1903504)2.89665333
152chaperone-mediated protein transport (GO:0072321)2.89571098
153protein complex biogenesis (GO:0070271)2.88783162
154negative regulation of mRNA metabolic process (GO:1903312)2.88264511
155somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.88157390
156isotype switching (GO:0045190)2.88157390
157somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.88157390
158* telomere maintenance (GO:0000723)2.87831430
159negative regulation of JAK-STAT cascade (GO:0046426)2.84722686
160pyrimidine nucleotide catabolic process (GO:0006244)2.83877741
161translational termination (GO:0006415)2.83169344
162* transcription-coupled nucleotide-excision repair (GO:0006283)2.82486163

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.90622514
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.08803616
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46976935
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.31535045
5* E2F4_17652178_ChIP-ChIP_JURKAT_Human2.95591986
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.95342820
7* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.86388533
8FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.76072466
9* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.68839502
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.60996769
11* ETS1_20019798_ChIP-Seq_JURKAT_Human2.34994399
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.29005461
13SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.28218601
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.24934416
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.13587120
16SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.06372893
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.06336660
18* GABP_17652178_ChIP-ChIP_JURKAT_Human2.02829145
19* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.00306704
20* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.99259489
21XRN2_22483619_ChIP-Seq_HELA_Human1.98494370
22KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.92708323
23KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.92708323
24KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.92708323
25PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.92608285
26THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92191721
27DCP1A_22483619_ChIP-Seq_HELA_Human1.86207599
28ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.83982271
29VDR_21846776_ChIP-Seq_THP-1_Human1.80576919
30* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.80255728
31GABP_19822575_ChIP-Seq_HepG2_Human1.79439648
32* E2F1_21310950_ChIP-Seq_MCF-7_Human1.77512209
33MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.77489526
34VDR_23849224_ChIP-Seq_CD4+_Human1.76902353
35* CREB1_15753290_ChIP-ChIP_HEK293T_Human1.76801584
36DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.76472785
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.72751205
38* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.72645803
39* TTF2_22483619_ChIP-Seq_HELA_Human1.65344812
40MYC_22102868_ChIP-Seq_BL_Human1.64456169
41* YY1_21170310_ChIP-Seq_MESCs_Mouse1.63146591
42PADI4_21655091_ChIP-ChIP_MCF-7_Human1.60246495
43KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.58227005
44STAT3_1855785_ChIP-Seq_MESCs_Mouse1.58196258
45POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.55704570
46MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.54997087
47MYC_18940864_ChIP-ChIP_HL60_Human1.52616148
48CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.50553935
49FOXP3_21729870_ChIP-Seq_TREG_Human1.50091706
50NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.49275051
51POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.49226404
52RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.46445674
53SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.46444333
54AR_21909140_ChIP-Seq_LNCAP_Human1.46339720
55HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.45336390
56* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.44655786
57MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.44036451
58KLF4_18555785_ChIP-Seq_MESCs_Mouse1.43235501
59* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.42842842
60NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.41968505
61TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41636192
62* KDM5A_27292631_Chip-Seq_BREAST_Human1.38639946
63NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.35802188
64CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.35349980
65SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.33433548
66CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.32052294
67* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.30886533
68IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.30509691
69* CIITA_25753668_ChIP-Seq_RAJI_Human1.28423599
70SOX2_18555785_ChIP-Seq_MESCs_Mouse1.28201814
71BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.28146515
72* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.27711185
73* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.26342135
74TCF3_18692474_ChIP-Seq_MEFs_Mouse1.25732773
75* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.24698417
76* NANOG_21062744_ChIP-ChIP_HESCs_Human1.23125584
77TCF3_18692474_ChIP-Seq_MESCs_Mouse1.22356053
78SRF_21415370_ChIP-Seq_HL-1_Mouse1.20721505
79PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.19472432
80CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.18211337
81POU5F1_16518401_ChIP-PET_MESCs_Mouse1.14975423
82* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.14266687
83ELF1_17652178_ChIP-ChIP_JURKAT_Human1.12687434
84* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12006718
85KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11692272
86E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.11449637
87CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09730065
88TFEB_21752829_ChIP-Seq_HELA_Human1.08838128
89SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.07244705
90NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.06820142
91FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.06803624
92* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.06793923
93ESR1_15608294_ChIP-ChIP_MCF-7_Human1.05706925
94CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.04953699
95DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.04038945
96ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.03701027
97* POU5F1_18692474_ChIP-Seq_MESCs_Mouse1.02320975
98* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.02313038
99TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01687947
100TP63_19390658_ChIP-ChIP_HaCaT_Human1.01123521
101SOX2_18692474_ChIP-Seq_MEFs_Mouse1.00493307
102SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.99035710
103ELK1_19687146_ChIP-ChIP_HELA_Human0.97688946
104HOXB4_20404135_ChIP-ChIP_EML_Mouse0.96644295
105* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.95838375
106SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.95146311
107NOTCH1_21737748_ChIP-Seq_TLL_Human0.94588708
108EGR1_19374776_ChIP-ChIP_THP-1_Human0.94301298
109SOX2_18692474_ChIP-Seq_MESCs_Mouse0.90215126
110SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.89011216
111CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88631582
112FLI1_27457419_Chip-Seq_LIVER_Mouse0.88402168
113ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.88382104
114SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.88355118
115* ERG_20887958_ChIP-Seq_HPC-7_Mouse0.88037369
116ELK1_22589737_ChIP-Seq_MCF10A_Human0.87925356
117FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.85625213
118EWS_26573619_Chip-Seq_HEK293_Human0.84835979
119ZNF274_21170338_ChIP-Seq_K562_Hela0.84007146
120GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.83822491
121HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.77604557
122* SPI1_23547873_ChIP-Seq_NB4_Human0.76381106
123NANOG_16153702_ChIP-ChIP_HESCs_Human0.76241102
124* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.75587596
125MYB_26560356_Chip-Seq_TH2_Human0.73656250
126* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71731331
127SOX2_16153702_ChIP-ChIP_HESCs_Human0.70258380
128POU5F1_16153702_ChIP-ChIP_HESCs_Human0.66430451
129IRF1_19129219_ChIP-ChIP_H3396_Human0.64494461
130SALL1_21062744_ChIP-ChIP_HESCs_Human0.63491991
131FUS_26573619_Chip-Seq_HEK293_Human0.60845917
132BP1_19119308_ChIP-ChIP_Hs578T_Human0.60107898
133VDR_22108803_ChIP-Seq_LS180_Human0.59790609
134TP53_22573176_ChIP-Seq_HFKS_Human0.59013520
135PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.58968028
136CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.58560661

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication6.41390021
2MP0010094_abnormal_chromosome_stability4.51402865
3MP0003693_abnormal_embryo_hatching3.83572376
4MP0004957_abnormal_blastocyst_morpholog3.68633660
5MP0003111_abnormal_nucleus_morphology3.66918001
6MP0008058_abnormal_DNA_repair3.33767494
7MP0003077_abnormal_cell_cycle3.14102410
8MP0009278_abnormal_bone_marrow2.89933838
9MP0010030_abnormal_orbit_morphology2.84499726
10MP0008877_abnormal_DNA_methylation2.61643412
11MP0000372_irregular_coat_pigmentation2.55655798
12MP0003786_premature_aging2.52105823
13MP0008932_abnormal_embryonic_tissue2.49006255
14MP0005171_absent_coat_pigmentation2.36424016
15MP0002938_white_spotting2.15140596
16MP0008995_early_reproductive_senescence2.01258777
17MP0002009_preneoplasia1.99313674
18MP0009697_abnormal_copulation1.99213451
19MP0003890_abnormal_embryonic-extraembry1.97572616
20MP0010352_gastrointestinal_tract_polyps1.95549442
21MP0005397_hematopoietic_system_phenotyp1.95311844
22MP0001545_abnormal_hematopoietic_system1.95311844
23MP0004233_abnormal_muscle_weight1.93903268
24MP0000350_abnormal_cell_proliferation1.90164819
25MP0008007_abnormal_cellular_replicative1.89942217
26MP0006036_abnormal_mitochondrial_physio1.86985616
27MP0001730_embryonic_growth_arrest1.86705475
28MP0000490_abnormal_crypts_of1.86066387
29MP0001697_abnormal_embryo_size1.77697737
30MP0002396_abnormal_hematopoietic_system1.71452422
31MP0004133_heterotaxia1.65450508
32MP0006035_abnormal_mitochondrial_morpho1.64417527
33MP0004147_increased_porphyrin_level1.64378126
34MP0005174_abnormal_tail_pigmentation1.63699101
35MP0001293_anophthalmia1.60490189
36MP0005380_embryogenesis_phenotype1.59535887
37MP0001672_abnormal_embryogenesis/_devel1.59535887
38MP0002085_abnormal_embryonic_tissue1.59512475
39MP0008789_abnormal_olfactory_epithelium1.58029497
40MP0002084_abnormal_developmental_patter1.56864156
41MP0002086_abnormal_extraembryonic_tissu1.56650265
42MP0003567_abnormal_fetal_cardiomyocyte1.55831444
43MP0005671_abnormal_response_to1.52956150
44MP0004197_abnormal_fetal_growth/weight/1.47375467
45MP0002019_abnormal_tumor_incidence1.47308030
46MP0003119_abnormal_digestive_system1.44515641
47MP0010307_abnormal_tumor_latency1.42305102
48MP0002080_prenatal_lethality1.39917030
49MP0003718_maternal_effect1.39667428
50MP0000566_synostosis1.37930824
51MP0002102_abnormal_ear_morphology1.37553111
52MP0005076_abnormal_cell_differentiation1.35315233
53MP0002653_abnormal_ependyma_morphology1.33679471
54MP0003186_abnormal_redox_activity1.32786483
55MP0005075_abnormal_melanosome_morpholog1.32737499
56MP0003984_embryonic_growth_retardation1.29882878
57MP0000313_abnormal_cell_death1.28342380
58MP0002088_abnormal_embryonic_growth/wei1.24654026
59MP0002095_abnormal_skin_pigmentation1.24079841
60MP0005408_hypopigmentation1.23421997
61MP0002249_abnormal_larynx_morphology1.22090768
62MP0009333_abnormal_splenocyte_physiolog1.20273043
63MP0002210_abnormal_sex_determination1.17739636
64MP0006072_abnormal_retinal_apoptosis1.17612938
65MP0001145_abnormal_male_reproductive1.17220344
66MP0000015_abnormal_ear_pigmentation1.14383124
67MP0003283_abnormal_digestive_organ1.09150653
68MP0008873_increased_physiological_sensi1.06693249
69MP0002111_abnormal_tail_morphology1.03009444
70MP0003763_abnormal_thymus_physiology1.02929496
71MP0002163_abnormal_gland_morphology1.02504756
72MP0002282_abnormal_trachea_morphology1.02326505
73MP0003123_paternal_imprinting1.02034100
74MP0001764_abnormal_homeostasis1.00964291
75MP0005394_taste/olfaction_phenotype1.00577520
76MP0005499_abnormal_olfactory_system1.00577520
77MP0001346_abnormal_lacrimal_gland0.98718295
78MP0000371_diluted_coat_color0.95096719
79MP0003453_abnormal_keratinocyte_physiol0.94303207
80MP0005645_abnormal_hypothalamus_physiol0.94239612
81MP0001929_abnormal_gametogenesis0.93804520
82MP0000653_abnormal_sex_gland0.92551656
83MP0000689_abnormal_spleen_morphology0.91785672
84MP0000703_abnormal_thymus_morphology0.89552136
85MP0005187_abnormal_penis_morphology0.88596892
86MP0003315_abnormal_perineum_morphology0.88499217
87MP0006292_abnormal_olfactory_placode0.88425275
88MP0005253_abnormal_eye_physiology0.85874363
89MP0001853_heart_inflammation0.85053695
90MP0002075_abnormal_coat/hair_pigmentati0.85002838
91MP0000470_abnormal_stomach_morphology0.83589126
92MP0002398_abnormal_bone_marrow0.81862503
93MP0009765_abnormal_xenobiotic_induced0.80683789
94MP0003121_genomic_imprinting0.80158093
95MP0000685_abnormal_immune_system0.80131127
96MP0000647_abnormal_sebaceous_gland0.79410752
97MP0002722_abnormal_immune_system0.79301190
98MP0005266_abnormal_metabolism0.78371532
99MP0001119_abnormal_female_reproductive0.77501470
100MP0002269_muscular_atrophy0.76922196
101MP0002405_respiratory_system_inflammati0.76407345
102MP0008872_abnormal_physiological_respon0.74192048
103MP0002114_abnormal_axial_skeleton0.72150395
104MP0002132_abnormal_respiratory_system0.72019987
105MP0001186_pigmentation_phenotype0.71764462
106MP0001727_abnormal_embryo_implantation0.71718079
107MP0002277_abnormal_respiratory_mucosa0.71198126
108MP0001529_abnormal_vocalization0.70874575
109MP0004808_abnormal_hematopoietic_stem0.70804123
110MP0009785_altered_susceptibility_to0.70612532
111MP0002148_abnormal_hypersensitivity_rea0.70445526
112MP0002932_abnormal_joint_morphology0.70300090
113MP0005410_abnormal_fertilization0.69820058
114MP0003698_abnormal_male_reproductive0.69398124
115MP0003787_abnormal_imprinting0.69341566
116MP0003656_abnormal_erythrocyte_physiolo0.68339138
117MP0009053_abnormal_anal_canal0.67775094
118MP0001835_abnormal_antigen_presentation0.67465915
119MP0003646_muscle_fatigue0.65887407
120MP0000477_abnormal_intestine_morphology0.65571716
121MP0003828_pulmonary_edema0.65409552
122MP0003941_abnormal_skin_development0.65141589
123MP0003806_abnormal_nucleotide_metabolis0.64015334
124MP0003755_abnormal_palate_morphology0.63551694
125MP0002420_abnormal_adaptive_immunity0.63272745
126MP0005501_abnormal_skin_physiology0.63173194
127MP0003935_abnormal_craniofacial_develop0.63071834
128MP0000716_abnormal_immune_system0.62646718
129MP0003136_yellow_coat_color0.61685592
130MP0000049_abnormal_middle_ear0.61653059
131MP0001819_abnormal_immune_cell0.61102033
132MP0002160_abnormal_reproductive_system0.60706296
133MP0001800_abnormal_humoral_immune0.59780980
134MP0005636_abnormal_mineral_homeostasis0.59747644
135MP0000579_abnormal_nail_morphology0.59693615
136MP0000432_abnormal_head_morphology0.59362951
137MP0002429_abnormal_blood_cell0.58997387
138MP0003699_abnormal_female_reproductive0.58356389
139MP0009672_abnormal_birth_weight0.57265341
140MP0001188_hyperpigmentation0.57212630
141MP0003448_altered_tumor_morphology0.56699890
142MP0003172_abnormal_lysosome_physiology0.56526587
143MP0004264_abnormal_extraembryonic_tissu0.55418274
144MP0002234_abnormal_pharynx_morphology0.55353838
145MP0005389_reproductive_system_phenotype0.55131188
146MP0003221_abnormal_cardiomyocyte_apopto0.55091337
147MP0000358_abnormal_cell_content/0.55075841
148MP0005647_abnormal_sex_gland0.55041553
149MP0003936_abnormal_reproductive_system0.54777931
150MP0005023_abnormal_wound_healing0.54161110

Predicted human phenotypes

RankGene SetZ-score
1Facial hemangioma (HP:0000329)4.31330031
2Rib fusion (HP:0000902)4.30100484
3Aplasia/Hypoplasia involving the carpal bones (HP:0006502)4.11824028
4Rectovaginal fistula (HP:0000143)4.08938727
5Rectal fistula (HP:0100590)4.08938727
6Concave nail (HP:0001598)3.99667069
7Aplastic anemia (HP:0001915)3.90057430
8Patellar aplasia (HP:0006443)3.87103508
9Acute necrotizing encephalopathy (HP:0006965)3.86266612
10Absent thumb (HP:0009777)3.79669841
11Absent radius (HP:0003974)3.78591464
12Poikiloderma (HP:0001029)3.73353674
13Abnormal mitochondria in muscle tissue (HP:0008316)3.65518067
14Birth length less than 3rd percentile (HP:0003561)3.64452844
15Pustule (HP:0200039)3.64270391
16Aplasia/Hypoplasia of the patella (HP:0006498)3.61766420
17Intestinal fistula (HP:0100819)3.61035680
18Absent forearm bone (HP:0003953)3.55876440
19Aplasia involving forearm bones (HP:0009822)3.55876440
20Annular pancreas (HP:0001734)3.55677233
21Mitochondrial inheritance (HP:0001427)3.51953635
22Selective tooth agenesis (HP:0001592)3.51852325
23Acute encephalopathy (HP:0006846)3.48879066
24Vaginal fistula (HP:0004320)3.45753789
25Breast hypoplasia (HP:0003187)3.43211523
26Hepatocellular necrosis (HP:0001404)3.38441032
27Tongue fasciculations (HP:0001308)3.37322469
28Increased CSF lactate (HP:0002490)3.36041637
29Increased IgM level (HP:0003496)3.34442985
30Premature graying of hair (HP:0002216)3.28960846
31Abnormality of cochlea (HP:0000375)3.24289363
32Aplasia/hypoplasia of the humerus (HP:0006507)3.24173074
33Basal cell carcinoma (HP:0002671)3.23150174
34Progressive macrocephaly (HP:0004481)3.15248796
35Squamous cell carcinoma (HP:0002860)3.15242743
36Abnormality of the ileum (HP:0001549)3.06924366
37Hepatic necrosis (HP:0002605)3.04227696
38Short humerus (HP:0005792)3.01972251
39Muscle fibrillation (HP:0010546)2.98813058
40Duodenal stenosis (HP:0100867)2.96832569
41Small intestinal stenosis (HP:0012848)2.96832569
42Increased hepatocellular lipid droplets (HP:0006565)2.93582456
43Intestinal atresia (HP:0011100)2.91837451
44Hypochromic microcytic anemia (HP:0004840)2.87943884
45Microvesicular hepatic steatosis (HP:0001414)2.85027677
46Methylmalonic acidemia (HP:0002912)2.81479269
47Reticulocytopenia (HP:0001896)2.80069323
48Pancytopenia (HP:0001876)2.79970760
49Abnormality of cells of the erythroid lineage (HP:0012130)2.77434499
50Abnormal hemoglobin (HP:0011902)2.76888293
51Abnormality of male internal genitalia (HP:0000022)2.73570846
52Abnormal number of erythroid precursors (HP:0012131)2.71990611
53Abnormality of the labia minora (HP:0012880)2.69136051
54Abnormal number of incisors (HP:0011064)2.65139008
55Cerebral edema (HP:0002181)2.64082914
56Chromosomal breakage induced by crosslinking agents (HP:0003221)2.64010202
57Orthostatic hypotension (HP:0001278)2.63944477
58Ulnar bowing (HP:0003031)2.63849916
59Decreased activity of mitochondrial respiratory chain (HP:0008972)2.63334578
60Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.63334578
61Broad alveolar ridges (HP:0000187)2.62641753
62Abnormality of the duodenum (HP:0002246)2.61140835
63Lipid accumulation in hepatocytes (HP:0006561)2.61039738
64Increased serum lactate (HP:0002151)2.60547711
65Ependymoma (HP:0002888)2.60454443
66Triphalangeal thumb (HP:0001199)2.58823326
67Chromsome breakage (HP:0040012)2.58311204
68Hypoplasia of the radius (HP:0002984)2.57725004
69Volvulus (HP:0002580)2.56660706
70Methylmalonic aciduria (HP:0012120)2.53372025
71Alopecia of scalp (HP:0002293)2.52693884
72Increased intramyocellular lipid droplets (HP:0012240)2.49937575
73Capillary hemangiomas (HP:0005306)2.47485022
74Morphological abnormality of the inner ear (HP:0011390)2.44999230
75Vertebral hypoplasia (HP:0008417)2.44752627
76Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.44752627
773-Methylglutaconic aciduria (HP:0003535)2.40930044
78Lactic acidosis (HP:0003128)2.37371251
79Male infertility (HP:0003251)2.37070643
80Acute lymphatic leukemia (HP:0006721)2.36810530
81Degeneration of anterior horn cells (HP:0002398)2.36676070
82Abnormality of the anterior horn cell (HP:0006802)2.36676070
83Muscle fiber atrophy (HP:0100295)2.36392560
84Medulloblastoma (HP:0002885)2.36318068
85Short thumb (HP:0009778)2.34921286
86Abnormal lung lobation (HP:0002101)2.34855567
87Rhabdomyosarcoma (HP:0002859)2.34822350
88Renal Fanconi syndrome (HP:0001994)2.33545575
89Astrocytoma (HP:0009592)2.31181045
90Abnormality of the astrocytes (HP:0100707)2.31181045
91Type I transferrin isoform profile (HP:0003642)2.30566562
92Cystic liver disease (HP:0006706)2.29702409
93Colon cancer (HP:0003003)2.29186023
94Meckel diverticulum (HP:0002245)2.28600467
95Back pain (HP:0003418)2.28495061
96Hyperglycinemia (HP:0002154)2.27790282
97Esophageal atresia (HP:0002032)2.26232424
98Abnormality of the aortic arch (HP:0012303)2.25708051
99Exercise intolerance (HP:0003546)2.24835189
100Aplasia/Hypoplasia of the uvula (HP:0010293)2.24751420
101Abnormality of the preputium (HP:0100587)2.24100238
102Type 2 muscle fiber atrophy (HP:0003554)2.19305308
103Oral leukoplakia (HP:0002745)2.18514872
104Albinism (HP:0001022)2.18010611
105Agnosia (HP:0010524)2.16593831
106Exertional dyspnea (HP:0002875)2.16451520
107Congenital hip dislocation (HP:0001374)2.15529269
108Aplasia/Hypoplasia of the sacrum (HP:0008517)2.14348416
109Short chin (HP:0000331)2.14066972
110Cerebral hypomyelination (HP:0006808)2.13923502
111Hypochromic anemia (HP:0001931)2.13083738
112Rough bone trabeculation (HP:0100670)2.12724862
113Abnormality of chromosome stability (HP:0003220)2.12604211
114Myelodysplasia (HP:0002863)2.12110258
115Carpal bone hypoplasia (HP:0001498)2.11909916
116Neoplasm of the oral cavity (HP:0100649)2.11421662
117Anteriorly placed anus (HP:0001545)2.10692909
118Prostate neoplasm (HP:0100787)2.10359353
119Clubbing of toes (HP:0100760)2.09877133
120IgG deficiency (HP:0004315)2.09786564
121Sloping forehead (HP:0000340)2.09367318
122Combined immunodeficiency (HP:0005387)2.06442881
123Impulsivity (HP:0100710)2.06120988
124Severe combined immunodeficiency (HP:0004430)2.05827678
125Coronal craniosynostosis (HP:0004440)2.05348685
126Dysautonomia (HP:0002459)2.05051462
127Premature skin wrinkling (HP:0100678)2.03581216
128Respiratory failure (HP:0002878)2.02954377
129Glioma (HP:0009733)2.02156246
130Respiratory difficulties (HP:0002880)2.01349515
131Turricephaly (HP:0000262)2.01324651
132Bifid uvula (HP:0000193)2.00803724
133IgM deficiency (HP:0002850)2.00779322
134Increased serum pyruvate (HP:0003542)2.00426025
135Cellular immunodeficiency (HP:0005374)1.99746637
136Spinal muscular atrophy (HP:0007269)1.97107154
137Optic disc pallor (HP:0000543)1.96909391
138Abnormality of the prostate (HP:0008775)1.96084306
139IgA deficiency (HP:0002720)1.95777646
140Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.95728935
141Supernumerary spleens (HP:0009799)1.95702415
142Bone marrow hypocellularity (HP:0005528)1.95056018
143Increased muscle lipid content (HP:0009058)1.94677889
144Leukodystrophy (HP:0002415)1.92472315
145Abnormality of glycolysis (HP:0004366)1.90296864
146Alacrima (HP:0000522)1.90102340
147Hypotelorism (HP:0000601)1.89741510
148Abnormality of the carotid arteries (HP:0005344)1.88188162
149Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.87809609
150Pancreatic cysts (HP:0001737)1.86623043
151Aplasia/Hypoplasia of the sternum (HP:0006714)1.84566189
152Abnormal protein glycosylation (HP:0012346)1.84537174
153Abnormal glycosylation (HP:0012345)1.84537174
154Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.84537174
155Abnormal protein N-linked glycosylation (HP:0012347)1.84537174
156Diaphragmatic weakness (HP:0009113)1.84363321
157Gastrointestinal atresia (HP:0002589)1.84251715
158Abnormality of serum amino acid levels (HP:0003112)1.83328933
159Short 5th finger (HP:0009237)1.82775901
160Aplasia/Hypoplasia involving the musculature (HP:0001460)1.82670144
161Nephroblastoma (Wilms tumor) (HP:0002667)1.82474550
162Vertebral fusion (HP:0002948)1.82460710
163Pancreatic islet-cell hyperplasia (HP:0004510)1.82239241
164Horseshoe kidney (HP:0000085)1.82108748
165Abnormality of aspartate family amino acid metabolism (HP:0010899)1.81056125
166Neoplasm of the adrenal gland (HP:0100631)1.79280729
167Abnormality of the pons (HP:0007361)1.78692016
168Breech presentation (HP:0001623)1.78512972
169CNS demyelination (HP:0007305)1.75570382
170Abnormality of methionine metabolism (HP:0010901)1.72188028
171Cleft eyelid (HP:0000625)1.71719703
172Pancreatic fibrosis (HP:0100732)1.71617142

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ICK4.15219248
2VRK23.67903252
3WEE13.32169996
4DDR23.31860045
5MAP3K63.28992101
6ZAK3.20035524
7CDC73.16609185
8MAPK153.13490930
9BUB13.08879619
10MAP3K112.97072668
11CDK72.50307403
12PINK12.32806473
13MST42.30797735
14PIM22.25547491
15MATK2.25234516
16DAPK12.08746112
17NME11.94609282
18NUAK11.93364781
19PBK1.92528646
20YES11.91403514
21EIF2AK11.88588253
22PLK11.88216868
23BCKDK1.83424857
24NEK21.82866181
25FGR1.81891144
26TYRO31.75444533
27DYRK31.74722883
28UHMK11.73100409
29KDR1.68178198
30TXK1.64702312
31CHEK21.63208241
32PIM11.55358160
33ACVR1B1.54117734
34TRIM281.49994620
35DYRK1B1.46461689
36TLK11.45182260
37CSK1.44487535
38PRKD21.42585021
39TTK1.32535999
40BRSK21.32148512
41SRPK11.31563055
42CDK61.31235106
43NEK11.28013107
44NME21.27146375
45BMX1.26846337
46* ATR1.22203522
47RPS6KB21.21311359
48AURKB1.18253186
49TESK21.16563567
50MAP4K21.11213795
51AURKA1.09149143
52RPS6KL11.07986620
53RPS6KC11.07986620
54WNK31.05550708
55PDGFRA1.01603879
56MAP3K101.00075063
57AKT30.99587537
58VRK10.98528119
59MAPK110.98265711
60CDK40.97757565
61BRSK10.97540702
62CSNK1G30.97535480
63RPS6KA60.96912315
64PLK40.95995114
65TAOK20.95883251
66EIF2AK20.95169624
67EIF2AK30.93341340
68CHEK10.91338349
69TRPM70.88201775
70MKNK10.87547939
71MKNK20.85758721
72CLK10.84112433
73* CDK20.81565634
74CDK120.80904639
75CSNK2A10.78846326
76STK160.77808578
77LATS20.76546085
78CDK80.76011039
79CSNK1G10.75779859
80MAP3K80.73075077
81CSNK1G20.70525349
82TSSK60.70385300
83PDK20.69411151
84TAF10.68292774
85PLK20.66563885
86CSNK2A20.65476600
87ERBB30.65303821
88CCNB10.64974118
89EPHA20.62540882
90STK40.60636624
91* ATM0.60200953
92CSNK1A1L0.59381264
93TEC0.58139872
94MAP4K10.57777096
95GSK3A0.57754934
96BMPR20.57066045
97DYRK20.56715262
98STK100.56407183
99RPS6KA10.55712727
100AKT20.55446708
101CDC42BPA0.54321734
102BMPR1B0.54171943
103FLT30.53317074
104KSR10.52840769
105* CDK10.50569997
106PAK60.49770049
107RPS6KA40.49761484
108RAF10.49298187
109PLK30.48110295
110MTOR0.47737303
111PASK0.47402026
112LYN0.47257580
113PAK40.46900607
114BCR0.46316214
115IKBKB0.45601628
116RPS6KA50.44855728
117PAK10.43881583
118PRPF4B0.42151121
119MARK30.42020329
120RPS6KB10.39823956
121ALK0.39094600
122MAPKAPK50.38254640
123CSF1R0.37869706
124BRAF0.37131214
125* PRKDC0.34776616
126PRKCI0.34686245
127FES0.34637877
128KSR20.33983039
129TAOK30.33852539
130PAK30.32861510
131HIPK20.32383226
132SCYL20.32212080
133RIPK40.32038717
134STK30.31925321
135MAPKAPK30.31781652
136PHKG10.31467635
137PHKG20.31467635
138MINK10.31384191
139MAPK10.29036100
140MAPK30.28608241
141MELK0.27542760
142CSNK1E0.26795069
143IKBKE0.26655371
144* MAPK140.26615926
145MAP3K120.24777953
146PNCK0.20519885
147OXSR10.20335050

Predicted pathways (KEGG)

RankGene SetZ-score
1* DNA replication_Homo sapiens_hsa030305.55411512
2* Mismatch repair_Homo sapiens_hsa034304.98722515
3Base excision repair_Homo sapiens_hsa034104.66284805
4Protein export_Homo sapiens_hsa030603.95846109
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.47210810
6Spliceosome_Homo sapiens_hsa030403.30017376
7Ribosome_Homo sapiens_hsa030102.95034526
8RNA transport_Homo sapiens_hsa030132.90062036
9* Nucleotide excision repair_Homo sapiens_hsa034202.85249733
10* Homologous recombination_Homo sapiens_hsa034402.63890248
11Cell cycle_Homo sapiens_hsa041102.63419489
12Proteasome_Homo sapiens_hsa030502.52383323
13Oxidative phosphorylation_Homo sapiens_hsa001902.43398823
14RNA polymerase_Homo sapiens_hsa030202.39427348
15* Fanconi anemia pathway_Homo sapiens_hsa034602.18574022
16One carbon pool by folate_Homo sapiens_hsa006702.15089315
17Fatty acid biosynthesis_Homo sapiens_hsa000612.09116097
18mRNA surveillance pathway_Homo sapiens_hsa030152.02419402
19Pyrimidine metabolism_Homo sapiens_hsa002401.98320210
20p53 signaling pathway_Homo sapiens_hsa041151.84305670
21Non-homologous end-joining_Homo sapiens_hsa034501.61716710
22Propanoate metabolism_Homo sapiens_hsa006401.60034866
23Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.57758057
24Basal transcription factors_Homo sapiens_hsa030221.52567056
25RNA degradation_Homo sapiens_hsa030181.47234971
26Fatty acid elongation_Homo sapiens_hsa000621.38661405
27Folate biosynthesis_Homo sapiens_hsa007901.31466130
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.29069897
29Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.27469135
30Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.23463015
31Sulfur relay system_Homo sapiens_hsa041221.23287119
32Alzheimers disease_Homo sapiens_hsa050101.20635438
33Biosynthesis of amino acids_Homo sapiens_hsa012301.20121541
34Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.11455586
35Pyruvate metabolism_Homo sapiens_hsa006201.10759774
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.09175006
37Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.08782657
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08272624
39Oocyte meiosis_Homo sapiens_hsa041141.05259025
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.03946631
41Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.02113819
42Notch signaling pathway_Homo sapiens_hsa043300.99140989
43Primary immunodeficiency_Homo sapiens_hsa053400.97754458
44Hippo signaling pathway_Homo sapiens_hsa043900.94839094
45Epstein-Barr virus infection_Homo sapiens_hsa051690.92297226
46Hedgehog signaling pathway_Homo sapiens_hsa043400.91809250
47Arginine and proline metabolism_Homo sapiens_hsa003300.90340545
48Transcriptional misregulation in cancer_Homo sapiens_hsa052020.86191404
49Purine metabolism_Homo sapiens_hsa002300.84652085
50Herpes simplex infection_Homo sapiens_hsa051680.82239546
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.81846876
522-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.81518532
53mTOR signaling pathway_Homo sapiens_hsa041500.78198865
54Viral carcinogenesis_Homo sapiens_hsa052030.78006413
55TGF-beta signaling pathway_Homo sapiens_hsa043500.73469414
56Shigellosis_Homo sapiens_hsa051310.72264038
57Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.71753713
58Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.71587314
59Bladder cancer_Homo sapiens_hsa052190.69651779
60Circadian rhythm_Homo sapiens_hsa047100.68311153
61Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.66512096
62Basal cell carcinoma_Homo sapiens_hsa052170.66341086
63Glutathione metabolism_Homo sapiens_hsa004800.64209271
64Caffeine metabolism_Homo sapiens_hsa002320.62884914
65Systemic lupus erythematosus_Homo sapiens_hsa053220.62699475
66Adherens junction_Homo sapiens_hsa045200.62035189
67Fructose and mannose metabolism_Homo sapiens_hsa000510.61828368
68Steroid biosynthesis_Homo sapiens_hsa001000.60642951
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.60088563
70MicroRNAs in cancer_Homo sapiens_hsa052060.59096258
71HTLV-I infection_Homo sapiens_hsa051660.58786384
72Legionellosis_Homo sapiens_hsa051340.58711890
73Thyroid cancer_Homo sapiens_hsa052160.58553594
74Peroxisome_Homo sapiens_hsa041460.57745786
75Cyanoamino acid metabolism_Homo sapiens_hsa004600.55678780
76Colorectal cancer_Homo sapiens_hsa052100.52852868
77Small cell lung cancer_Homo sapiens_hsa052220.51619552
78Wnt signaling pathway_Homo sapiens_hsa043100.51319161
79Phototransduction_Homo sapiens_hsa047440.49957657
80Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.48413027
81Autoimmune thyroid disease_Homo sapiens_hsa053200.47301095
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.46348411
83Pentose phosphate pathway_Homo sapiens_hsa000300.45612989
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.45467818
85Selenocompound metabolism_Homo sapiens_hsa004500.42912026
86SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41357740
87Lysine degradation_Homo sapiens_hsa003100.41243210
88Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41116197
89Antigen processing and presentation_Homo sapiens_hsa046120.40869108
90Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.39839567
91Type I diabetes mellitus_Homo sapiens_hsa049400.38749928
92Longevity regulating pathway - mammal_Homo sapiens_hsa042110.37632515
93Huntingtons disease_Homo sapiens_hsa050160.37447220
94Butanoate metabolism_Homo sapiens_hsa006500.37151941
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.37058371
96Galactose metabolism_Homo sapiens_hsa000520.36417887
97Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36222027
98Allograft rejection_Homo sapiens_hsa053300.34310368
99Cardiac muscle contraction_Homo sapiens_hsa042600.33456866
100Viral myocarditis_Homo sapiens_hsa054160.31802595
101Hepatitis B_Homo sapiens_hsa051610.31441415
102Graft-versus-host disease_Homo sapiens_hsa053320.31313970
103Measles_Homo sapiens_hsa051620.31035312
104Chronic myeloid leukemia_Homo sapiens_hsa052200.30778039
105Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.30615130
106Fatty acid metabolism_Homo sapiens_hsa012120.29525091
107Acute myeloid leukemia_Homo sapiens_hsa052210.29166746
108N-Glycan biosynthesis_Homo sapiens_hsa005100.28765909
109Hematopoietic cell lineage_Homo sapiens_hsa046400.27628506
110Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.22969867
111VEGF signaling pathway_Homo sapiens_hsa043700.22637097
112Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.22514373
113Asthma_Homo sapiens_hsa053100.21583760
114Apoptosis_Homo sapiens_hsa042100.20631317
115Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.20104033
116Carbon metabolism_Homo sapiens_hsa012000.19368641
117Collecting duct acid secretion_Homo sapiens_hsa049660.19044691
118Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.17927466
119Tryptophan metabolism_Homo sapiens_hsa003800.17539719
120Metabolic pathways_Homo sapiens_hsa011000.17020480
121Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.16629924
122Pathways in cancer_Homo sapiens_hsa052000.16627535
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.16285720
124Nitrogen metabolism_Homo sapiens_hsa009100.16216611
125Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.15898534
126Tight junction_Homo sapiens_hsa045300.15205644
127Regulation of autophagy_Homo sapiens_hsa041400.15137256
128Regulation of actin cytoskeleton_Homo sapiens_hsa048100.13920933
129Pentose and glucuronate interconversions_Homo sapiens_hsa000400.13903528
130Parkinsons disease_Homo sapiens_hsa050120.13655905
131beta-Alanine metabolism_Homo sapiens_hsa004100.12721488
132Vitamin B6 metabolism_Homo sapiens_hsa007500.12154436
133Glycosaminoglycan degradation_Homo sapiens_hsa005310.11499977
134HIF-1 signaling pathway_Homo sapiens_hsa040660.11028725
135Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.10794967
136Rheumatoid arthritis_Homo sapiens_hsa053230.10656911
137Prostate cancer_Homo sapiens_hsa052150.09943092
138Olfactory transduction_Homo sapiens_hsa047400.09323504
139Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.09179026
140Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.08924277
141PI3K-Akt signaling pathway_Homo sapiens_hsa041510.08766609
142Intestinal immune network for IgA production_Homo sapiens_hsa046720.08402217

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »