

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neuron fate determination (GO:0048664) | 7.93023641 |
| 2 | DNA deamination (GO:0045006) | 6.25823333 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.54524489 |
| 4 | hepatocyte differentiation (GO:0070365) | 4.59195633 |
| 5 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 4.57575194 |
| 6 | sulfate transport (GO:0008272) | 4.41617317 |
| 7 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.32124195 |
| 8 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.32124195 |
| 9 | NADH dehydrogenase complex assembly (GO:0010257) | 4.32124195 |
| 10 | resolution of meiotic recombination intermediates (GO:0000712) | 4.31744895 |
| 11 | DNA catabolic process, exonucleolytic (GO:0000738) | 4.21754678 |
| 12 | spinal cord association neuron differentiation (GO:0021527) | 4.21566206 |
| 13 | ribonucleoprotein complex disassembly (GO:0032988) | 4.10891526 |
| 14 | cytidine metabolic process (GO:0046087) | 4.08483887 |
| 15 | cytidine catabolic process (GO:0006216) | 4.08483887 |
| 16 | cytidine deamination (GO:0009972) | 4.08483887 |
| 17 | protein-cofactor linkage (GO:0018065) | 4.01663251 |
| 18 | negative regulation of cell aging (GO:0090344) | 4.00712573 |
| 19 | specification of organ identity (GO:0010092) | 3.95134832 |
| 20 | positive regulation of lamellipodium assembly (GO:0010592) | 3.86277885 |
| 21 | inner mitochondrial membrane organization (GO:0007007) | 3.78157995 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.74883735 |
| 23 | chaperone-mediated protein transport (GO:0072321) | 3.57640964 |
| 24 | heart field specification (GO:0003128) | 3.57269511 |
| 25 | secondary heart field specification (GO:0003139) | 3.57269511 |
| 26 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.56891292 |
| 27 | organelle disassembly (GO:1903008) | 3.56854694 |
| 28 | DNA double-strand break processing (GO:0000729) | 3.50639536 |
| 29 | DNA demethylation (GO:0080111) | 3.49978503 |
| 30 | retinal ganglion cell axon guidance (GO:0031290) | 3.49956695 |
| 31 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 3.45286699 |
| 32 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.43655462 |
| 33 | negative regulation of telomere maintenance (GO:0032205) | 3.42001901 |
| 34 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.41908283 |
| 35 | protein complex biogenesis (GO:0070271) | 3.41684951 |
| 36 | protein localization to cilium (GO:0061512) | 3.35563384 |
| 37 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.34320828 |
| 38 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.33347797 |
| 39 | opioid receptor signaling pathway (GO:0038003) | 3.30711453 |
| 40 | respiratory electron transport chain (GO:0022904) | 3.28689256 |
| 41 | hematopoietic stem cell proliferation (GO:0071425) | 3.27933373 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.24470247 |
| 43 | electron transport chain (GO:0022900) | 3.24439066 |
| 44 | rhodopsin mediated signaling pathway (GO:0016056) | 3.23345951 |
| 45 | positive regulation of Notch signaling pathway (GO:0045747) | 3.19777579 |
| 46 | prenylation (GO:0097354) | 3.18839090 |
| 47 | protein prenylation (GO:0018342) | 3.18839090 |
| 48 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.18279317 |
| 49 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.16892225 |
| 50 | ATP synthesis coupled proton transport (GO:0015986) | 3.15285870 |
| 51 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.15285870 |
| 52 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 3.13959609 |
| 53 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 3.11744467 |
| 54 | detection of calcium ion (GO:0005513) | 3.09754155 |
| 55 | positive regulation of lamellipodium organization (GO:1902745) | 3.07879228 |
| 56 | negative regulation of interleukin-1 beta production (GO:0032691) | 3.06433107 |
| 57 | mismatch repair (GO:0006298) | 3.04301065 |
| 58 | positive T cell selection (GO:0043368) | 3.02744291 |
| 59 | radial glial cell differentiation (GO:0060019) | 3.02308291 |
| 60 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.00484626 |
| 61 | positive regulation of cell fate commitment (GO:0010455) | 2.94676438 |
| 62 | positive regulation of action potential (GO:0045760) | 2.94290232 |
| 63 | mitochondrial genome maintenance (GO:0000002) | 2.93717247 |
| 64 | DNA dealkylation (GO:0035510) | 2.90645228 |
| 65 | neuron fate specification (GO:0048665) | 2.88235350 |
| 66 | midbrain development (GO:0030901) | 2.88037565 |
| 67 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.82896810 |
| 68 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.82034642 |
| 69 | behavioral response to nicotine (GO:0035095) | 2.81459975 |
| 70 | heparin metabolic process (GO:0030202) | 2.78013261 |
| 71 | heparin biosynthetic process (GO:0030210) | 2.78013261 |
| 72 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.76958948 |
| 73 | cellular ketone body metabolic process (GO:0046950) | 2.76264799 |
| 74 | regulation of immunoglobulin secretion (GO:0051023) | 2.72672163 |
| 75 | platelet dense granule organization (GO:0060155) | 2.72487940 |
| 76 | intraciliary transport (GO:0042073) | 2.70444373 |
| 77 | signal peptide processing (GO:0006465) | 2.69765247 |
| 78 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.69680839 |
| 79 | protein neddylation (GO:0045116) | 2.67725112 |
| 80 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.66580810 |
| 81 | inner ear receptor stereocilium organization (GO:0060122) | 2.66291824 |
| 82 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 2.62500728 |
| 83 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.61291141 |
| 84 | cell differentiation in spinal cord (GO:0021515) | 2.60666702 |
| 85 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.59900474 |
| 86 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.59900474 |
| 87 | alpha-beta T cell differentiation (GO:0046632) | 2.58495711 |
| 88 | cullin deneddylation (GO:0010388) | 2.58478944 |
| 89 | cGMP biosynthetic process (GO:0006182) | 2.54054792 |
| 90 | regulation of voltage-gated calcium channel activity (GO:1901385) | 2.53700949 |
| 91 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.52978325 |
| 92 | purine nucleobase biosynthetic process (GO:0009113) | 2.52928294 |
| 93 | anterograde axon cargo transport (GO:0008089) | 2.50124767 |
| 94 | negative regulation of interleukin-12 production (GO:0032695) | 2.49471605 |
| 95 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.49335883 |
| 96 | ketone body metabolic process (GO:1902224) | 2.45998650 |
| 97 | male meiosis (GO:0007140) | 2.45913355 |
| 98 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.45901528 |
| 99 | hydrogen ion transmembrane transport (GO:1902600) | 2.45388811 |
| 100 | sequestering of actin monomers (GO:0042989) | 11.2566766 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.30608471 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.92034067 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.74967014 |
| 4 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.60975476 |
| 5 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 3.38259234 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.08829461 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.79256024 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.76344246 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.69196244 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.67154946 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.62762980 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.57769203 |
| 13 | FUS_26573619_Chip-Seq_HEK293_Human | 2.30057303 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.27578318 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.22189655 |
| 16 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.20250578 |
| 17 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 2.19833345 |
| 18 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.15692871 |
| 19 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.14563933 |
| 20 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.12943457 |
| 21 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.09903435 |
| 22 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.01411215 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.97939531 |
| 24 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.89993396 |
| 25 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.81134679 |
| 26 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.79526738 |
| 27 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.73549447 |
| 28 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.73324101 |
| 29 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.72499300 |
| 30 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.68805137 |
| 31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.65382218 |
| 32 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.62153889 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.60835388 |
| 34 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.58309507 |
| 35 | P300_19829295_ChIP-Seq_ESCs_Human | 1.53957605 |
| 36 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.53474127 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.53147630 |
| 38 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.48269365 |
| 39 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.48232132 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.48085914 |
| 41 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.46505881 |
| 42 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.45565816 |
| 43 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.45099837 |
| 44 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.42025712 |
| 45 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.42005131 |
| 46 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.41082974 |
| 47 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.39918464 |
| 48 | EWS_26573619_Chip-Seq_HEK293_Human | 1.39566336 |
| 49 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.37828639 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.37770897 |
| 51 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.37466942 |
| 52 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.37131213 |
| 53 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.35510988 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.34420315 |
| 55 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.32920422 |
| 56 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.29297735 |
| 57 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.28934936 |
| 58 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.28777831 |
| 59 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.27511084 |
| 60 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.26784779 |
| 61 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26154959 |
| 62 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.25720780 |
| 63 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.25627304 |
| 64 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.25601630 |
| 65 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.24991516 |
| 66 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.23762723 |
| 67 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.22822529 |
| 68 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.22399174 |
| 69 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.20942253 |
| 70 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19462104 |
| 71 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19462104 |
| 72 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.17476653 |
| 73 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.16328707 |
| 74 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.16328707 |
| 75 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.16044592 |
| 76 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.15757914 |
| 77 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.14835581 |
| 78 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.14746375 |
| 79 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.11861905 |
| 80 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.09594860 |
| 81 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.08433399 |
| 82 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.08037027 |
| 83 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.07977345 |
| 84 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.07272646 |
| 85 | AR_25329375_ChIP-Seq_VCAP_Human | 1.06896595 |
| 86 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.06877599 |
| 87 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.05900470 |
| 88 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.04279852 |
| 89 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.03420199 |
| 90 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.03232033 |
| 91 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.02794705 |
| 92 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.01444877 |
| 93 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.01371217 |
| 94 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.97897065 |
| 95 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.97432636 |
| 96 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.96958709 |
| 97 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.96397498 |
| 98 | JUN_21703547_ChIP-Seq_K562_Human | 0.96002555 |
| 99 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.95756562 |
| 100 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.94591394 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000566_synostosis | 4.20751352 |
| 2 | MP0003136_yellow_coat_color | 4.19867950 |
| 3 | MP0003011_delayed_dark_adaptation | 4.05759714 |
| 4 | MP0002234_abnormal_pharynx_morphology | 3.32882945 |
| 5 | MP0002163_abnormal_gland_morphology | 3.22331079 |
| 6 | MP0001529_abnormal_vocalization | 3.10188292 |
| 7 | MP0002938_white_spotting | 2.99832333 |
| 8 | MP0005187_abnormal_penis_morphology | 2.77053549 |
| 9 | MP0002249_abnormal_larynx_morphology | 2.68002404 |
| 10 | MP0010030_abnormal_orbit_morphology | 2.56519384 |
| 11 | MP0005671_abnormal_response_to | 2.47867438 |
| 12 | MP0005379_endocrine/exocrine_gland_phen | 2.26247047 |
| 13 | MP0005310_abnormal_salivary_gland | 2.20129167 |
| 14 | MP0003880_abnormal_central_pattern | 2.15671646 |
| 15 | MP0004142_abnormal_muscle_tone | 2.12366417 |
| 16 | MP0000372_irregular_coat_pigmentation | 1.96195419 |
| 17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.93569850 |
| 18 | MP0000579_abnormal_nail_morphology | 1.85820042 |
| 19 | MP0004742_abnormal_vestibular_system | 1.84977759 |
| 20 | MP0001501_abnormal_sleep_pattern | 1.78064817 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.73372511 |
| 22 | MP0009785_altered_susceptibility_to | 1.71782825 |
| 23 | MP0001486_abnormal_startle_reflex | 1.67933001 |
| 24 | MP0002272_abnormal_nervous_system | 1.54227838 |
| 25 | MP0002638_abnormal_pupillary_reflex | 1.50932511 |
| 26 | MP0006292_abnormal_olfactory_placode | 1.48209427 |
| 27 | MP0009745_abnormal_behavioral_response | 1.47279086 |
| 28 | MP0010386_abnormal_urinary_bladder | 1.43625071 |
| 29 | MP0001188_hyperpigmentation | 1.41191184 |
| 30 | MP0000647_abnormal_sebaceous_gland | 1.36550202 |
| 31 | MP0005253_abnormal_eye_physiology | 1.35258558 |
| 32 | MP0004381_abnormal_hair_follicle | 1.34347008 |
| 33 | MP0002735_abnormal_chemical_nociception | 1.33792975 |
| 34 | MP0005387_immune_system_phenotype | 1.33010361 |
| 35 | MP0001790_abnormal_immune_system | 1.33010361 |
| 36 | MP0009046_muscle_twitch | 1.31861293 |
| 37 | MP0000569_abnormal_digit_pigmentation | 1.30703353 |
| 38 | MP0002933_joint_inflammation | 1.21401928 |
| 39 | MP0001970_abnormal_pain_threshold | 1.19585950 |
| 40 | MP0002557_abnormal_social/conspecific_i | 1.18705112 |
| 41 | MP0005645_abnormal_hypothalamus_physiol | 1.16507367 |
| 42 | MP0005248_abnormal_Harderian_gland | 1.16262960 |
| 43 | MP0010155_abnormal_intestine_physiology | 1.15847780 |
| 44 | MP0002736_abnormal_nociception_after | 1.13963962 |
| 45 | MP0006276_abnormal_autonomic_nervous | 1.13267163 |
| 46 | MP0001919_abnormal_reproductive_system | 1.11710485 |
| 47 | MP0000631_abnormal_neuroendocrine_gland | 1.10613351 |
| 48 | MP0002876_abnormal_thyroid_physiology | 1.09648480 |
| 49 | MP0001984_abnormal_olfaction | 1.09534356 |
| 50 | MP0005551_abnormal_eye_electrophysiolog | 1.09035477 |
| 51 | MP0006035_abnormal_mitochondrial_morpho | 1.08395411 |
| 52 | MP0001968_abnormal_touch/_nociception | 1.06137811 |
| 53 | MP0002095_abnormal_skin_pigmentation | 1.03264762 |
| 54 | MP0002138_abnormal_hepatobiliary_system | 1.02090821 |
| 55 | MP0009697_abnormal_copulation | 0.98923832 |
| 56 | MP0003638_abnormal_response/metabolism_ | 0.97648926 |
| 57 | MP0002148_abnormal_hypersensitivity_rea | 0.97327133 |
| 58 | MP0004147_increased_porphyrin_level | 0.96015822 |
| 59 | MP0005386_behavior/neurological_phenoty | 0.93587819 |
| 60 | MP0004924_abnormal_behavior | 0.93587819 |
| 61 | MP0001346_abnormal_lacrimal_gland | 0.92934776 |
| 62 | MP0008058_abnormal_DNA_repair | 0.92774703 |
| 63 | MP0005075_abnormal_melanosome_morpholog | 0.92564612 |
| 64 | MP0005535_abnormal_body_temperature | 0.91419924 |
| 65 | MP0000538_abnormal_urinary_bladder | 0.91047118 |
| 66 | MP0008873_increased_physiological_sensi | 0.86213575 |
| 67 | MP0002733_abnormal_thermal_nociception | 0.86039228 |
| 68 | MP0002067_abnormal_sensory_capabilities | 0.83850168 |
| 69 | MP0000026_abnormal_inner_ear | 0.83773448 |
| 70 | MP0002752_abnormal_somatic_nervous | 0.83640468 |
| 71 | MP0002102_abnormal_ear_morphology | 0.83190892 |
| 72 | MP0005085_abnormal_gallbladder_physiolo | 0.82105860 |
| 73 | MP0003315_abnormal_perineum_morphology | 0.81895940 |
| 74 | MP0001800_abnormal_humoral_immune | 0.80682999 |
| 75 | MP0001905_abnormal_dopamine_level | 0.79968949 |
| 76 | MP0002277_abnormal_respiratory_mucosa | 0.77548966 |
| 77 | MP0002075_abnormal_coat/hair_pigmentati | 0.75652548 |
| 78 | MP0002160_abnormal_reproductive_system | 0.75235222 |
| 79 | MP0002184_abnormal_innervation | 0.73708469 |
| 80 | MP0006072_abnormal_retinal_apoptosis | 0.72737897 |
| 81 | MP0002572_abnormal_emotion/affect_behav | 0.72624835 |
| 82 | MP0008789_abnormal_olfactory_epithelium | 0.72376950 |
| 83 | MP0002837_dystrophic_cardiac_calcinosis | 0.71136383 |
| 84 | MP0002132_abnormal_respiratory_system | 0.70367615 |
| 85 | MP0002282_abnormal_trachea_morphology | 0.69708951 |
| 86 | MP0005408_hypopigmentation | 0.69595847 |
| 87 | MP0000490_abnormal_crypts_of | 0.69131947 |
| 88 | MP0001986_abnormal_taste_sensitivity | 0.67253357 |
| 89 | MP0001873_stomach_inflammation | 0.66944409 |
| 90 | MP0008961_abnormal_basal_metabolism | 0.65410651 |
| 91 | MP0004215_abnormal_myocardial_fiber | 0.65243069 |
| 92 | MP0002063_abnormal_learning/memory/cond | 0.64729686 |
| 93 | MP0000230_abnormal_systemic_arterial | 0.64413205 |
| 94 | MP0004085_abnormal_heartbeat | 0.64299566 |
| 95 | MP0001186_pigmentation_phenotype | 0.64009563 |
| 96 | MP0002723_abnormal_immune_serum | 0.63988172 |
| 97 | MP0003938_abnormal_ear_development | 0.62954899 |
| 98 | MP0002210_abnormal_sex_determination | 0.62470207 |
| 99 | MP0005423_abnormal_somatic_nervous | 0.61595885 |
| 100 | MP0008872_abnormal_physiological_respon | 0.61354044 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hypoplasia of the pons (HP:0012110) | 6.16639775 |
| 2 | Abnormality of the pons (HP:0007361) | 5.63837494 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 4.83993989 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 4.29499479 |
| 5 | Decreased central vision (HP:0007663) | 4.25934483 |
| 6 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 4.14562077 |
| 7 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 4.14562077 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.78533733 |
| 9 | Retrobulbar optic neuritis (HP:0100654) | 3.74707136 |
| 10 | Optic neuritis (HP:0100653) | 3.74707136 |
| 11 | Gastrointestinal infarctions (HP:0005244) | 3.52167048 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 3.50589535 |
| 13 | Mitochondrial inheritance (HP:0001427) | 3.48947476 |
| 14 | Respiratory difficulties (HP:0002880) | 3.46964889 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 3.45344013 |
| 16 | Focal motor seizures (HP:0011153) | 3.32417443 |
| 17 | Increased CSF lactate (HP:0002490) | 3.31367490 |
| 18 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.30316452 |
| 19 | Absent/shortened dynein arms (HP:0200106) | 3.30316452 |
| 20 | Increased intramyocellular lipid droplets (HP:0012240) | 3.11113881 |
| 21 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.10197845 |
| 22 | Orchitis (HP:0100796) | 3.09703438 |
| 23 | Keratoconjunctivitis sicca (HP:0001097) | 3.06629082 |
| 24 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.02677621 |
| 25 | Keratoconjunctivitis (HP:0001096) | 2.91776375 |
| 26 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.87035093 |
| 27 | Arthropathy (HP:0003040) | 2.84878267 |
| 28 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.84360270 |
| 29 | Exertional dyspnea (HP:0002875) | 2.84102267 |
| 30 | Progressive macrocephaly (HP:0004481) | 2.83742115 |
| 31 | Acute encephalopathy (HP:0006846) | 2.81993276 |
| 32 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.80071954 |
| 33 | Hemoptysis (HP:0002105) | 2.76786776 |
| 34 | Congenital, generalized hypertrichosis (HP:0004540) | 2.69770271 |
| 35 | Submucous cleft hard palate (HP:0000176) | 2.67355252 |
| 36 | Absent eyebrow (HP:0002223) | 2.63780248 |
| 37 | Hepatocellular necrosis (HP:0001404) | 2.60708748 |
| 38 | Inability to walk (HP:0002540) | 2.57786805 |
| 39 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.56667818 |
| 40 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.56667818 |
| 41 | Myositis (HP:0100614) | 2.49842819 |
| 42 | Increased muscle lipid content (HP:0009058) | 2.45858901 |
| 43 | 3-Methylglutaconic aciduria (HP:0003535) | 2.43252465 |
| 44 | Abnormal lung lobation (HP:0002101) | 2.43243630 |
| 45 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.42726795 |
| 46 | Progressive inability to walk (HP:0002505) | 2.41734625 |
| 47 | Hyperglycinuria (HP:0003108) | 2.39737262 |
| 48 | Peritonitis (HP:0002586) | 2.38988563 |
| 49 | Chronic sinusitis (HP:0011109) | 2.37845551 |
| 50 | Oligodactyly (HP:0012165) | 2.33588346 |
| 51 | Hepatic necrosis (HP:0002605) | 2.33068087 |
| 52 | Absence seizures (HP:0002121) | 2.22773855 |
| 53 | Increased serum lactate (HP:0002151) | 2.21966493 |
| 54 | Optic disc pallor (HP:0000543) | 2.21630007 |
| 55 | Cerebral edema (HP:0002181) | 2.21018251 |
| 56 | Acute hepatic failure (HP:0006554) | 2.20922687 |
| 57 | Type II lissencephaly (HP:0007260) | 2.18398040 |
| 58 | Recurrent cutaneous fungal infections (HP:0011370) | 2.18069161 |
| 59 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.18069161 |
| 60 | Increased corneal curvature (HP:0100692) | 2.17607711 |
| 61 | Keratoconus (HP:0000563) | 2.17607711 |
| 62 | Abnormal number of erythroid precursors (HP:0012131) | 2.16557636 |
| 63 | Abnormality of serum amino acid levels (HP:0003112) | 2.14410787 |
| 64 | Gangrene (HP:0100758) | 2.06252452 |
| 65 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.05242830 |
| 66 | Congenital stationary night blindness (HP:0007642) | 2.03224791 |
| 67 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.01565830 |
| 68 | Dialeptic seizures (HP:0011146) | 2.01553970 |
| 69 | Rhinitis (HP:0012384) | 2.00262035 |
| 70 | Severe combined immunodeficiency (HP:0004430) | 1.99820061 |
| 71 | Encephalitis (HP:0002383) | 1.99605171 |
| 72 | Abnormal ciliary motility (HP:0012262) | 1.98835640 |
| 73 | Septo-optic dysplasia (HP:0100842) | 1.98679076 |
| 74 | Chronic otitis media (HP:0000389) | 1.98210517 |
| 75 | Leukodystrophy (HP:0002415) | 1.97239659 |
| 76 | Hypoproteinemia (HP:0003075) | 1.96878811 |
| 77 | Concave nail (HP:0001598) | 1.96345119 |
| 78 | Glycosuria (HP:0003076) | 1.96170975 |
| 79 | Abnormality of urine glucose concentration (HP:0011016) | 1.96170975 |
| 80 | Postaxial foot polydactyly (HP:0001830) | 1.94446900 |
| 81 | Pulmonary infiltrates (HP:0002113) | 1.93965829 |
| 82 | Hyperphosphaturia (HP:0003109) | 1.92487079 |
| 83 | Nephronophthisis (HP:0000090) | 1.91113655 |
| 84 | Thyroiditis (HP:0100646) | 1.89853836 |
| 85 | Supernumerary spleens (HP:0009799) | 1.89363059 |
| 86 | Attenuation of retinal blood vessels (HP:0007843) | 1.87467957 |
| 87 | Exercise intolerance (HP:0003546) | 1.86923518 |
| 88 | Cone-rod dystrophy (HP:0000548) | 1.86922886 |
| 89 | Ulnar claw (HP:0001178) | 1.82030366 |
| 90 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.81798068 |
| 91 | Lactic acidosis (HP:0003128) | 1.81176066 |
| 92 | Chest pain (HP:0100749) | 1.79592023 |
| 93 | Abnormality of renal resorption (HP:0011038) | 1.78085079 |
| 94 | Increased serum pyruvate (HP:0003542) | 1.77165628 |
| 95 | Facial hemangioma (HP:0000329) | 1.75951722 |
| 96 | Abnormality of the aortic arch (HP:0012303) | 1.75583023 |
| 97 | Leukocytosis (HP:0001974) | 1.74675559 |
| 98 | Autoimmune thrombocytopenia (HP:0001973) | 1.73224224 |
| 99 | Fair hair (HP:0002286) | 1.72765409 |
| 100 | Renal tubular dysfunction (HP:0000124) | 1.71642711 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 5.15332766 |
| 2 | AKT3 | 4.19138479 |
| 3 | GRK7 | 4.10830919 |
| 4 | TLK1 | 4.01795448 |
| 5 | NEK1 | 3.70267422 |
| 6 | RIPK4 | 3.12141907 |
| 7 | EIF2AK1 | 2.80383483 |
| 8 | TXK | 2.75421793 |
| 9 | EPHA3 | 2.45236407 |
| 10 | TNIK | 2.32998311 |
| 11 | TSSK6 | 2.29586967 |
| 12 | PNCK | 2.14952874 |
| 13 | MST4 | 1.90164066 |
| 14 | DYRK3 | 1.87234458 |
| 15 | WNK3 | 1.85253378 |
| 16 | BUB1 | 1.83717740 |
| 17 | PASK | 1.83227548 |
| 18 | SRPK1 | 1.77357180 |
| 19 | EIF2AK3 | 1.65230539 |
| 20 | TYK2 | 1.62342836 |
| 21 | MAPK13 | 1.49103173 |
| 22 | PINK1 | 1.45268602 |
| 23 | PLK4 | 1.44406897 |
| 24 | PHKG2 | 1.41356347 |
| 25 | PHKG1 | 1.41356347 |
| 26 | SGK2 | 1.29027786 |
| 27 | KIT | 1.14935623 |
| 28 | MAP3K3 | 1.11435708 |
| 29 | ZAK | 1.09698664 |
| 30 | VRK1 | 1.06825812 |
| 31 | ALK | 1.05613733 |
| 32 | MARK1 | 0.98282239 |
| 33 | TIE1 | 0.93766437 |
| 34 | JAK3 | 0.91511382 |
| 35 | DYRK2 | 0.89606261 |
| 36 | MAPK11 | 0.88937090 |
| 37 | TAOK3 | 0.88719312 |
| 38 | IKBKE | 0.87558185 |
| 39 | FRK | 0.84196979 |
| 40 | EPHA4 | 0.83500572 |
| 41 | SGK223 | 0.82654807 |
| 42 | SGK494 | 0.82654807 |
| 43 | ERBB3 | 0.82624135 |
| 44 | GRK1 | 0.80363999 |
| 45 | IRAK1 | 0.72137027 |
| 46 | BRAF | 0.72050778 |
| 47 | IKBKB | 0.69261670 |
| 48 | TAOK1 | 0.68686900 |
| 49 | CAMKK2 | 0.68223901 |
| 50 | STK38L | 0.67842316 |
| 51 | PLK3 | 0.66540253 |
| 52 | OXSR1 | 0.65800481 |
| 53 | YES1 | 0.65064447 |
| 54 | ADRBK1 | 0.64098595 |
| 55 | CAMK1G | 0.62221982 |
| 56 | MKNK2 | 0.61358249 |
| 57 | PRKCE | 0.58438567 |
| 58 | CAMK2A | 0.57224258 |
| 59 | STK10 | 0.56649559 |
| 60 | VRK2 | 0.53044186 |
| 61 | EPHB1 | 0.51145356 |
| 62 | FGFR3 | 0.50894387 |
| 63 | INSRR | 0.50777662 |
| 64 | MAP3K9 | 0.49153749 |
| 65 | PAK3 | 0.48352798 |
| 66 | CAMKK1 | 0.46631764 |
| 67 | LCK | 0.46175873 |
| 68 | TRPM7 | 0.44637559 |
| 69 | BCR | 0.43908081 |
| 70 | PRKCG | 0.41560162 |
| 71 | FGFR4 | 0.40902183 |
| 72 | EIF2AK2 | 0.40049379 |
| 73 | PRKCQ | 0.39217381 |
| 74 | PRKACA | 0.37103588 |
| 75 | NME2 | 0.36483246 |
| 76 | PLK2 | 0.36348961 |
| 77 | WNK4 | 0.35981674 |
| 78 | TGFBR2 | 0.35436296 |
| 79 | MAP2K6 | 0.35227078 |
| 80 | PIK3CG | 0.35073812 |
| 81 | MAP2K3 | 0.34189212 |
| 82 | CLK1 | 0.34164399 |
| 83 | ATR | 0.32633160 |
| 84 | PRKCZ | 0.32131430 |
| 85 | SGK3 | 0.31922951 |
| 86 | MKNK1 | 0.31532732 |
| 87 | CSNK1E | 0.30849131 |
| 88 | PRKG1 | 0.30533881 |
| 89 | MAP4K1 | 0.29915315 |
| 90 | DAPK2 | 0.28993796 |
| 91 | NTRK3 | 0.28236206 |
| 92 | WEE1 | 0.26943099 |
| 93 | SYK | 0.25172848 |
| 94 | MAP3K4 | 0.24970859 |
| 95 | OBSCN | 0.23572627 |
| 96 | CSNK2A2 | 0.23444133 |
| 97 | NME1 | 0.22244781 |
| 98 | RPS6KA5 | 0.22154488 |
| 99 | SIK3 | 0.21053303 |
| 100 | JAK2 | 0.20245586 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.83759283 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.66733647 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.64559375 |
| 4 | Caffeine metabolism_Homo sapiens_hsa00232 | 3.46477393 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.35584728 |
| 6 | Protein export_Homo sapiens_hsa03060 | 3.18666810 |
| 7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.77900204 |
| 8 | Phototransduction_Homo sapiens_hsa04744 | 2.64225881 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.28662937 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.28051996 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.27360555 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.14283983 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.03963679 |
| 14 | Ribosome_Homo sapiens_hsa03010 | 1.96195703 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.91748645 |
| 16 | Mismatch repair_Homo sapiens_hsa03430 | 1.82851162 |
| 17 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.68618991 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.65656770 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.57003410 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.54778780 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.50976661 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.48675723 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.47993292 |
| 24 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.47234736 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.46005550 |
| 26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.44752181 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.43208008 |
| 28 | Olfactory transduction_Homo sapiens_hsa04740 | 1.43171304 |
| 29 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.41654316 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.38101174 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.30187498 |
| 32 | RNA polymerase_Homo sapiens_hsa03020 | 1.25561463 |
| 33 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.25501767 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.22646825 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.17790911 |
| 36 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.16876427 |
| 37 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.15061031 |
| 38 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.13192610 |
| 39 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.08334779 |
| 40 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.04972947 |
| 41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.02043605 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.01735693 |
| 43 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.00764838 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.99406890 |
| 45 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.89911813 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.88509548 |
| 47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.82010141 |
| 48 | Nicotine addiction_Homo sapiens_hsa05033 | 0.81740294 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.75733704 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.70536011 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.69716515 |
| 52 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.69120841 |
| 53 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.67335698 |
| 54 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.67053548 |
| 55 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.65686514 |
| 56 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64950997 |
| 57 | Morphine addiction_Homo sapiens_hsa05032 | 0.63407728 |
| 58 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.62921796 |
| 59 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.60028493 |
| 60 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.58644290 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58226507 |
| 62 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.56752475 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.56302025 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.53109332 |
| 65 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.52735560 |
| 66 | DNA replication_Homo sapiens_hsa03030 | 0.51063625 |
| 67 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.49642621 |
| 68 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.49604898 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48737119 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.47556821 |
| 71 | Spliceosome_Homo sapiens_hsa03040 | 0.46796994 |
| 72 | RNA transport_Homo sapiens_hsa03013 | 0.46669152 |
| 73 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.46457737 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.43561759 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.43123696 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40531184 |
| 77 | Base excision repair_Homo sapiens_hsa03410 | 0.38687255 |
| 78 | Viral myocarditis_Homo sapiens_hsa05416 | 0.38339874 |
| 79 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37680454 |
| 80 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37536808 |
| 81 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.35986368 |
| 82 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.33808976 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.33753640 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.33152054 |
| 85 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.31369710 |
| 86 | Peroxisome_Homo sapiens_hsa04146 | 0.30994208 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.29658978 |
| 88 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.29393183 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.28546185 |
| 90 | GABAergic synapse_Homo sapiens_hsa04727 | 0.28094599 |
| 91 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.27171633 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26560785 |
| 93 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26124515 |
| 94 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.25707199 |
| 95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.24692597 |
| 96 | Renin secretion_Homo sapiens_hsa04924 | 0.24279571 |
| 97 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.24193842 |
| 98 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.23454317 |
| 99 | Salivary secretion_Homo sapiens_hsa04970 | 0.22080577 |
| 100 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.21622389 |

