Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 8.62123021 |
2 | * viral transcription (GO:0019083) | 8.58259469 |
3 | * translational termination (GO:0006415) | 8.25943245 |
4 | ribosomal small subunit biogenesis (GO:0042274) | 7.57817244 |
5 | * translational elongation (GO:0006414) | 7.09825346 |
6 | * SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.94866474 |
7 | * cotranslational protein targeting to membrane (GO:0006613) | 6.79123907 |
8 | * protein targeting to ER (GO:0045047) | 6.78526694 |
9 | maturation of SSU-rRNA (GO:0030490) | 6.58960063 |
10 | * nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.57212289 |
11 | * establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.47681063 |
12 | * viral life cycle (GO:0019058) | 6.35684429 |
13 | * cellular protein complex disassembly (GO:0043624) | 6.35488448 |
14 | * protein localization to endoplasmic reticulum (GO:0070972) | 6.32305309 |
15 | * translational initiation (GO:0006413) | 6.19187545 |
16 | * protein complex disassembly (GO:0043241) | 5.66027278 |
17 | ribosomal large subunit biogenesis (GO:0042273) | 5.41627468 |
18 | * macromolecular complex disassembly (GO:0032984) | 5.26229574 |
19 | * nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.82737974 |
20 | * mRNA catabolic process (GO:0006402) | 4.58993786 |
21 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.47682847 |
22 | * protein targeting to membrane (GO:0006612) | 4.45324130 |
23 | formation of translation preinitiation complex (GO:0001731) | 4.38322357 |
24 | * RNA catabolic process (GO:0006401) | 4.33826472 |
25 | * translation (GO:0006412) | 4.30454800 |
26 | DNA deamination (GO:0045006) | 3.98430930 |
27 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.93802352 |
28 | DNA unwinding involved in DNA replication (GO:0006268) | 3.87095911 |
29 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.85779418 |
30 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.84146254 |
31 | DNA strand elongation (GO:0022616) | 3.75260935 |
32 | rRNA processing (GO:0006364) | 3.61137310 |
33 | DNA replication initiation (GO:0006270) | 3.52517364 |
34 | rRNA metabolic process (GO:0016072) | 3.48076091 |
35 | ATP synthesis coupled proton transport (GO:0015986) | 3.43523578 |
36 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.43523578 |
37 | telomere maintenance via recombination (GO:0000722) | 3.34782903 |
38 | negative regulation of RNA splicing (GO:0033119) | 3.34124669 |
39 | cellular component biogenesis (GO:0044085) | 3.23363045 |
40 | * protein localization to membrane (GO:0072657) | 3.18875083 |
41 | mitotic recombination (GO:0006312) | 3.16010478 |
42 | protein localization to kinetochore (GO:0034501) | 3.15829336 |
43 | mitotic chromosome condensation (GO:0007076) | 3.10639635 |
44 | telomere maintenance via telomere lengthening (GO:0010833) | 3.07402954 |
45 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.98163198 |
46 | * establishment of protein localization to membrane (GO:0090150) | 2.96979126 |
47 | ribosome biogenesis (GO:0042254) | 2.96786525 |
48 | nucleobase biosynthetic process (GO:0046112) | 2.95920519 |
49 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.95310446 |
50 | IMP biosynthetic process (GO:0006188) | 2.95177366 |
51 | regulation of mitochondrial translation (GO:0070129) | 2.94281594 |
52 | establishment of integrated proviral latency (GO:0075713) | 2.90803080 |
53 | pseudouridine synthesis (GO:0001522) | 2.90707712 |
54 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.87011856 |
55 | heterochromatin organization (GO:0070828) | 2.86738224 |
56 | oxidative phosphorylation (GO:0006119) | 2.86560869 |
57 | mitotic nuclear envelope disassembly (GO:0007077) | 2.86310924 |
58 | * establishment of protein localization to organelle (GO:0072594) | 2.80284959 |
59 | spliceosomal snRNP assembly (GO:0000387) | 2.79334446 |
60 | CENP-A containing nucleosome assembly (GO:0034080) | 2.77446580 |
61 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.76187485 |
62 | ncRNA 3-end processing (GO:0043628) | 2.76149828 |
63 | chromatin remodeling at centromere (GO:0031055) | 2.72981856 |
64 | kinetochore organization (GO:0051383) | 2.72943425 |
65 | protein localization to chromosome, centromeric region (GO:0071459) | 2.72856236 |
66 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.70631589 |
67 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.70631589 |
68 | * protein targeting (GO:0006605) | 2.66661514 |
69 | IMP metabolic process (GO:0046040) | 2.64893039 |
70 | DNA replication checkpoint (GO:0000076) | 2.64867545 |
71 | DNA topological change (GO:0006265) | 2.64817165 |
72 | * protein localization to organelle (GO:0033365) | 2.63790734 |
73 | myeloid cell homeostasis (GO:0002262) | 2.62625589 |
74 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.62039991 |
75 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.61856314 |
76 | DNA replication-independent nucleosome organization (GO:0034724) | 2.61856314 |
77 | establishment of viral latency (GO:0019043) | 2.60427646 |
78 | membrane disassembly (GO:0030397) | 2.59001935 |
79 | nuclear envelope disassembly (GO:0051081) | 2.59001935 |
80 | ribosome assembly (GO:0042255) | 2.58610779 |
81 | regulation of protein heterodimerization activity (GO:0043497) | 2.58557659 |
82 | mRNA splicing, via spliceosome (GO:0000398) | 2.55695502 |
83 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.55695502 |
84 | RNA splicing, via transesterification reactions (GO:0000375) | 2.55427531 |
85 | ncRNA processing (GO:0034470) | 2.55020991 |
86 | chaperone-mediated protein transport (GO:0072321) | 2.54909590 |
87 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.54028959 |
88 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.53697493 |
89 | termination of RNA polymerase II transcription (GO:0006369) | 2.53597781 |
90 | purine nucleobase biosynthetic process (GO:0009113) | 2.52814952 |
91 | spliceosomal complex assembly (GO:0000245) | 2.52333587 |
92 | * gene expression (GO:0010467) | 2.52121561 |
93 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.52047297 |
94 | regulation of histone H3-K9 methylation (GO:0051570) | 2.50487903 |
95 | nuclear pore organization (GO:0006999) | 2.49585079 |
96 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.48872106 |
97 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.48296366 |
98 | kinetochore assembly (GO:0051382) | 2.48169520 |
99 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.46889461 |
100 | ribonucleoprotein complex assembly (GO:0022618) | 2.45127363 |
101 | histone mRNA metabolic process (GO:0008334) | 2.44777581 |
102 | rRNA transcription (GO:0009303) | 2.43119450 |
103 | DNA duplex unwinding (GO:0032508) | 2.42786716 |
104 | * cellular component disassembly (GO:0022411) | 2.42381554 |
105 | negative regulation of mRNA processing (GO:0050686) | 2.42253350 |
106 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.40945634 |
107 | DNA geometric change (GO:0032392) | 2.40422782 |
108 | nuclear pore complex assembly (GO:0051292) | 2.40167514 |
109 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.37665702 |
110 | telomere maintenance (GO:0000723) | 2.37487867 |
111 | ncRNA metabolic process (GO:0034660) | 2.37226606 |
112 | inner mitochondrial membrane organization (GO:0007007) | 2.36863261 |
113 | telomere organization (GO:0032200) | 2.35671135 |
114 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.35289434 |
115 | mitotic metaphase plate congression (GO:0007080) | 2.34543892 |
116 | T cell apoptotic process (GO:0070231) | 2.33041599 |
117 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.32655540 |
118 | regulation of translational initiation (GO:0006446) | 2.32452400 |
119 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.31295048 |
120 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.30673186 |
121 | viral mRNA export from host cell nucleus (GO:0046784) | 2.29715651 |
122 | ribonucleoprotein complex subunit organization (GO:0071826) | 2.29510428 |
123 | regulation of translational fidelity (GO:0006450) | 2.29453604 |
124 | base-excision repair (GO:0006284) | 2.29154329 |
125 | proteasome assembly (GO:0043248) | 2.27982786 |
126 | chromatin assembly or disassembly (GO:0006333) | 2.27676666 |
127 | UTP biosynthetic process (GO:0006228) | 2.27501092 |
128 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.26612037 |
129 | negative regulation of DNA repair (GO:0045738) | 2.26481860 |
130 | proline biosynthetic process (GO:0006561) | 2.26343734 |
131 | respiratory electron transport chain (GO:0022904) | 2.26292077 |
132 | histone arginine methylation (GO:0034969) | 2.25514473 |
133 | protein targeting to mitochondrion (GO:0006626) | 2.25008137 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.24690208 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.64860779 |
3 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.98660170 |
4 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.32622800 |
5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.19989472 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.15800232 |
7 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.07735496 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.85100697 |
9 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.78885988 |
10 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.76749438 |
11 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.71869263 |
12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.62869306 |
13 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.60204341 |
14 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.55073271 |
15 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.36571330 |
16 | * HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.30240794 |
17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.26682066 |
18 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.24073721 |
19 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.23624041 |
20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.22194873 |
21 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.19485864 |
22 | MYC_22102868_ChIP-Seq_BL_Human | 2.16978941 |
23 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.14001089 |
24 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.13619597 |
25 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.12208429 |
26 | * TTF2_22483619_ChIP-Seq_HELA_Human | 2.04529933 |
27 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.98615955 |
28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91559747 |
29 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.88669809 |
30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.84963714 |
31 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.80610690 |
32 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.80446819 |
33 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.71591901 |
34 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.70661998 |
35 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.70409138 |
36 | * VDR_21846776_ChIP-Seq_THP-1_Human | 1.67451942 |
37 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.66762446 |
38 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.62924189 |
39 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.61848794 |
40 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.61031940 |
41 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.55114797 |
42 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.54300798 |
43 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.52865740 |
44 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52336897 |
45 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.49491239 |
46 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.48726319 |
47 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.48312420 |
48 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.47485625 |
49 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.47253840 |
50 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.46870027 |
51 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.46860064 |
52 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.46139795 |
53 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42260039 |
54 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.39944396 |
55 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.39690987 |
56 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.39471473 |
57 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.39279074 |
58 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.33477667 |
59 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.31584721 |
60 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.30461394 |
61 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.30232489 |
62 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30084838 |
63 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.29014401 |
64 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.28407623 |
65 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.28011604 |
66 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.27963924 |
67 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.24992426 |
68 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.23766761 |
69 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.23389829 |
70 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.21850141 |
71 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.20573733 |
72 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.20196079 |
73 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.19042567 |
74 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16035391 |
75 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.14005257 |
76 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.13359668 |
77 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.13157871 |
78 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.12865330 |
79 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07566845 |
80 | * CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07412918 |
81 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.06939640 |
82 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.06798133 |
83 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.06317264 |
84 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.06145989 |
85 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.05887818 |
86 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.05421048 |
87 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.03888418 |
88 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.03057542 |
89 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.02701051 |
90 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.02560882 |
91 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.02530485 |
92 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.01491991 |
93 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.01101465 |
94 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.00378837 |
95 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00203240 |
96 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.99291715 |
97 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.99023748 |
98 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.98948309 |
99 | * CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.98587854 |
100 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.96950806 |
101 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.96537318 |
102 | MAF_26560356_Chip-Seq_TH1_Human | 0.96116574 |
103 | * UTX_26944678_Chip-Seq_JUKART_Human | 0.95844679 |
104 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.95823753 |
105 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.95475097 |
106 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.95475097 |
107 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.95475097 |
108 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.95354040 |
109 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.94134525 |
110 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91390076 |
111 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.90755375 |
112 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.90362664 |
113 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.90158433 |
114 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.89925255 |
115 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.89441558 |
116 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.88852403 |
117 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.88731389 |
118 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.87298367 |
119 | MAF_26560356_Chip-Seq_TH2_Human | 0.86746928 |
120 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86032100 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 3.95378376 |
2 | MP0009379_abnormal_foot_pigmentation | 3.39579828 |
3 | MP0004957_abnormal_blastocyst_morpholog | 3.34795866 |
4 | MP0010094_abnormal_chromosome_stability | 3.18027132 |
5 | MP0002396_abnormal_hematopoietic_system | 3.11489930 |
6 | MP0003077_abnormal_cell_cycle | 2.98831945 |
7 | MP0003111_abnormal_nucleus_morphology | 2.87532979 |
8 | MP0008057_abnormal_DNA_replication | 2.84444880 |
9 | MP0008007_abnormal_cellular_replicative | 2.31906757 |
10 | MP0010352_gastrointestinal_tract_polyps | 2.22162679 |
11 | MP0008058_abnormal_DNA_repair | 2.21648471 |
12 | MP0004808_abnormal_hematopoietic_stem | 2.04575420 |
13 | MP0000490_abnormal_crypts_of | 1.98487159 |
14 | MP0003763_abnormal_thymus_physiology | 1.91987864 |
15 | MP0000566_synostosis | 1.86880054 |
16 | MP0008932_abnormal_embryonic_tissue | 1.75802617 |
17 | MP0005397_hematopoietic_system_phenotyp | 1.75197213 |
18 | MP0001545_abnormal_hematopoietic_system | 1.75197213 |
19 | MP0006054_spinal_hemorrhage | 1.71416186 |
20 | MP0000350_abnormal_cell_proliferation | 1.69661728 |
21 | MP0003786_premature_aging | 1.63001533 |
22 | MP0009333_abnormal_splenocyte_physiolog | 1.60423643 |
23 | MP0003567_abnormal_fetal_cardiomyocyte | 1.58465544 |
24 | MP0004185_abnormal_adipocyte_glucose | 1.58393323 |
25 | MP0001730_embryonic_growth_arrest | 1.55308428 |
26 | MP0010030_abnormal_orbit_morphology | 1.46091326 |
27 | MP0002398_abnormal_bone_marrow | 1.45065022 |
28 | MP0002009_preneoplasia | 1.43523036 |
29 | MP0003123_paternal_imprinting | 1.40193518 |
30 | MP0000703_abnormal_thymus_morphology | 1.39178058 |
31 | MP0005174_abnormal_tail_pigmentation | 1.36726367 |
32 | MP0002722_abnormal_immune_system | 1.36330713 |
33 | MP0002019_abnormal_tumor_incidence | 1.35271895 |
34 | MP0002166_altered_tumor_susceptibility | 1.34633658 |
35 | MP0003941_abnormal_skin_development | 1.34224903 |
36 | MP0000685_abnormal_immune_system | 1.33326811 |
37 | MP0010307_abnormal_tumor_latency | 1.30050120 |
38 | MP0003705_abnormal_hypodermis_morpholog | 1.27788985 |
39 | MP0001346_abnormal_lacrimal_gland | 1.25686963 |
40 | MP0000313_abnormal_cell_death | 1.25444875 |
41 | MP0001697_abnormal_embryo_size | 1.25269888 |
42 | MP0000689_abnormal_spleen_morphology | 1.24858093 |
43 | MP0001835_abnormal_antigen_presentation | 1.24263499 |
44 | MP0004197_abnormal_fetal_growth/weight/ | 1.20461600 |
45 | MP0002080_prenatal_lethality | 1.18989322 |
46 | MP0001293_anophthalmia | 1.17065166 |
47 | MP0001672_abnormal_embryogenesis/_devel | 1.16291829 |
48 | MP0005380_embryogenesis_phenotype | 1.16291829 |
49 | MP0002163_abnormal_gland_morphology | 1.16159087 |
50 | MP0001800_abnormal_humoral_immune | 1.14375033 |
51 | MP0002697_abnormal_eye_size | 1.13912973 |
52 | MP0001853_heart_inflammation | 1.13626130 |
53 | MP0000858_altered_metastatic_potential | 1.12986145 |
54 | MP0002006_tumorigenesis | 1.12619911 |
55 | MP0002095_abnormal_skin_pigmentation | 1.12105802 |
56 | MP0002429_abnormal_blood_cell | 1.12088717 |
57 | MP0002938_white_spotting | 1.12021517 |
58 | MP0005075_abnormal_melanosome_morpholog | 1.11796556 |
59 | MP0002086_abnormal_extraembryonic_tissu | 1.10584879 |
60 | MP0002085_abnormal_embryonic_tissue | 1.10043227 |
61 | MP0009672_abnormal_birth_weight | 1.10027363 |
62 | MP0000465_gastrointestinal_hemorrhage | 1.09649453 |
63 | MP0009278_abnormal_bone_marrow | 1.09408792 |
64 | MP0003984_embryonic_growth_retardation | 1.08757834 |
65 | MP0002088_abnormal_embryonic_growth/wei | 1.07971127 |
66 | MP0002084_abnormal_developmental_patter | 1.07721051 |
67 | MP0000716_abnormal_immune_system | 1.05290914 |
68 | MP0005023_abnormal_wound_healing | 1.03441953 |
69 | MP0002132_abnormal_respiratory_system | 1.02862375 |
70 | MP0005501_abnormal_skin_physiology | 1.01063339 |
71 | MP0002420_abnormal_adaptive_immunity | 0.99473030 |
72 | MP0001873_stomach_inflammation | 0.97217335 |
73 | MP0002452_abnormal_antigen_presenting | 0.97211362 |
74 | MP0001819_abnormal_immune_cell | 0.97001462 |
75 | MP0005671_abnormal_response_to | 0.96442508 |
76 | MP0003806_abnormal_nucleotide_metabolis | 0.96316564 |
77 | MP0000678_abnormal_parathyroid_gland | 0.96074681 |
78 | MP0002405_respiratory_system_inflammati | 0.95710255 |
79 | MP0000762_abnormal_tongue_morphology | 0.93955138 |
80 | MP0001881_abnormal_mammary_gland | 0.92832175 |
81 | MP0003315_abnormal_perineum_morphology | 0.91893905 |
82 | MP0004264_abnormal_extraembryonic_tissu | 0.90776728 |
83 | MP0010155_abnormal_intestine_physiology | 0.89063055 |
84 | MP0005076_abnormal_cell_differentiation | 0.88790382 |
85 | MP0002723_abnormal_immune_serum | 0.87958097 |
86 | MP0003436_decreased_susceptibility_to | 0.87459953 |
87 | MP0009053_abnormal_anal_canal | 0.84411359 |
88 | MP0002877_abnormal_melanocyte_morpholog | 0.84064244 |
89 | MP0000537_abnormal_urethra_morphology | 0.82524356 |
90 | MP0005025_abnormal_response_to | 0.82434845 |
91 | MP0002210_abnormal_sex_determination | 0.82299521 |
92 | MP0000428_abnormal_craniofacial_morphol | 0.81324600 |
93 | MP0000049_abnormal_middle_ear | 0.79989349 |
94 | MP0003566_abnormal_cell_adhesion | 0.79459616 |
95 | MP0000477_abnormal_intestine_morphology | 0.77511091 |
96 | MP0002249_abnormal_larynx_morphology | 0.76816221 |
97 | MP0006035_abnormal_mitochondrial_morpho | 0.76349713 |
98 | MP0001727_abnormal_embryo_implantation | 0.76347253 |
99 | MP0003121_genomic_imprinting | 0.75935030 |
100 | MP0002111_abnormal_tail_morphology | 0.75078533 |
101 | MP0009785_altered_susceptibility_to | 0.74945907 |
102 | MP0005000_abnormal_immune_tolerance | 0.74264593 |
103 | MP0001849_ear_inflammation | 0.73719814 |
104 | MP0002282_abnormal_trachea_morphology | 0.72858417 |
105 | MP0001145_abnormal_male_reproductive | 0.72796265 |
106 | MP0001340_abnormal_eyelid_morphology | 0.72765818 |
107 | MP0001661_extended_life_span | 0.72721892 |
108 | MP0002092_abnormal_eye_morphology | 0.72607733 |
109 | MP0001915_intracranial_hemorrhage | 0.72124116 |
110 | MP0005408_hypopigmentation | 0.71940219 |
111 | MP0002060_abnormal_skin_morphology | 0.71839122 |
112 | MP0001216_abnormal_epidermal_layer | 0.71416052 |
113 | MP0003186_abnormal_redox_activity | 0.71021527 |
114 | MP0003718_maternal_effect | 0.70819328 |
115 | MP0000383_abnormal_hair_follicle | 0.70295892 |
116 | MP0002098_abnormal_vibrissa_morphology | 0.70278379 |
117 | MP0006292_abnormal_olfactory_placode | 0.69627797 |
118 | MP0008789_abnormal_olfactory_epithelium | 0.69432859 |
119 | MP0000377_abnormal_hair_follicle | 0.69402482 |
120 | MP0002796_impaired_skin_barrier | 0.68979893 |
121 | MP0000358_abnormal_cell_content/ | 0.68604914 |
122 | MP0009931_abnormal_skin_appearance | 0.68318425 |
123 | MP0001286_abnormal_eye_development | 0.67671918 |
124 | MP0005464_abnormal_platelet_physiology | 0.67625608 |
125 | MP0002932_abnormal_joint_morphology | 0.66191247 |
126 | MP0008995_early_reproductive_senescence | 0.65859027 |
127 | MP0006036_abnormal_mitochondrial_physio | 0.63493138 |
128 | MP0005666_abnormal_adipose_tissue | 0.63141001 |
129 | MP0000733_abnormal_muscle_development | 0.62979019 |
130 | MP0003942_abnormal_urinary_system | 0.62814241 |
131 | MP0000627_abnormal_mammary_gland | 0.62700558 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 8.08293078 |
2 | Reticulocytopenia (HP:0001896) | 7.61029245 |
3 | Abnormal number of erythroid precursors (HP:0012131) | 7.40148249 |
4 | Macrocytic anemia (HP:0001972) | 5.22359988 |
5 | Pallor (HP:0000980) | 5.16680910 |
6 | Thrombocytosis (HP:0001894) | 3.92554321 |
7 | Colon cancer (HP:0003003) | 3.85851375 |
8 | Aplastic anemia (HP:0001915) | 3.74850913 |
9 | Microvesicular hepatic steatosis (HP:0001414) | 3.63725173 |
10 | 11 pairs of ribs (HP:0000878) | 3.12466077 |
11 | Selective tooth agenesis (HP:0001592) | 3.11384301 |
12 | Oral leukoplakia (HP:0002745) | 2.85630947 |
13 | Absent thumb (HP:0009777) | 2.82184213 |
14 | Abnormality of reticulocytes (HP:0004312) | 2.80998712 |
15 | IgM deficiency (HP:0002850) | 2.79335759 |
16 | Progressive muscle weakness (HP:0003323) | 2.72011299 |
17 | Partial duplication of thumb phalanx (HP:0009944) | 2.69923600 |
18 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.68816188 |
19 | Lipid accumulation in hepatocytes (HP:0006561) | 2.56486153 |
20 | Birth length less than 3rd percentile (HP:0003561) | 2.55228274 |
21 | Abnormal number of incisors (HP:0011064) | 2.51528206 |
22 | Abnormality of the parietal bone (HP:0002696) | 2.49719929 |
23 | Increased intramyocellular lipid droplets (HP:0012240) | 2.49371228 |
24 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.43677962 |
25 | Myelodysplasia (HP:0002863) | 2.41951959 |
26 | Acute necrotizing encephalopathy (HP:0006965) | 2.38988296 |
27 | Abnormal hemoglobin (HP:0011902) | 2.38948603 |
28 | Trismus (HP:0000211) | 2.36168968 |
29 | Depressed nasal ridge (HP:0000457) | 2.34661142 |
30 | Agammaglobulinemia (HP:0004432) | 2.29796834 |
31 | Basal cell carcinoma (HP:0002671) | 2.27311374 |
32 | Duplication of thumb phalanx (HP:0009942) | 2.25737031 |
33 | Asplenia (HP:0001746) | 2.21230618 |
34 | Acute encephalopathy (HP:0006846) | 2.20767335 |
35 | Mitochondrial inheritance (HP:0001427) | 2.16727478 |
36 | Increased muscle lipid content (HP:0009058) | 2.16335026 |
37 | Stenosis of the external auditory canal (HP:0000402) | 2.15705791 |
38 | Panhypogammaglobulinemia (HP:0003139) | 2.14767041 |
39 | Chromsome breakage (HP:0040012) | 2.14696295 |
40 | Multiple enchondromatosis (HP:0005701) | 2.12700877 |
41 | Poikiloderma (HP:0001029) | 2.12412633 |
42 | Atresia of the external auditory canal (HP:0000413) | 2.10625892 |
43 | Missing ribs (HP:0000921) | 2.10313922 |
44 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.09329063 |
45 | Thick lower lip vermilion (HP:0000179) | 2.07542266 |
46 | Medulloblastoma (HP:0002885) | 2.06767154 |
47 | Broad distal phalanx of finger (HP:0009836) | 2.06603537 |
48 | Nasolacrimal duct obstruction (HP:0000579) | 2.05733739 |
49 | Seborrheic dermatitis (HP:0001051) | 2.05407529 |
50 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.03304558 |
51 | Congenital, generalized hypertrichosis (HP:0004540) | 2.02100825 |
52 | Rough bone trabeculation (HP:0100670) | 2.01885259 |
53 | Glossoptosis (HP:0000162) | 2.01695276 |
54 | Microretrognathia (HP:0000308) | 2.00020751 |
55 | Triphalangeal thumb (HP:0001199) | 1.99640085 |
56 | Abnormality of the preputium (HP:0100587) | 1.98893180 |
57 | Proximal placement of thumb (HP:0009623) | 1.97273725 |
58 | Petechiae (HP:0000967) | 1.97189529 |
59 | Migraine (HP:0002076) | 1.96655280 |
60 | Colitis (HP:0002583) | 1.96551528 |
61 | Neoplasm of the pancreas (HP:0002894) | 1.96249791 |
62 | Hepatocellular necrosis (HP:0001404) | 1.96173025 |
63 | Breast hypoplasia (HP:0003187) | 1.95867948 |
64 | Patellar aplasia (HP:0006443) | 1.95730942 |
65 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.95094464 |
66 | Squamous cell carcinoma (HP:0002860) | 1.92364885 |
67 | Amaurosis fugax (HP:0100576) | 1.91045966 |
68 | Deviation of the thumb (HP:0009603) | 1.90648591 |
69 | Carpal bone hypoplasia (HP:0001498) | 1.89475534 |
70 | Progressive external ophthalmoplegia (HP:0000590) | 1.89395809 |
71 | Acute lymphatic leukemia (HP:0006721) | 1.88709632 |
72 | Increased CSF lactate (HP:0002490) | 1.87981186 |
73 | Hypoplasia of the radius (HP:0002984) | 1.87763365 |
74 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.87714812 |
75 | Premature graying of hair (HP:0002216) | 1.86747442 |
76 | Lymphoma (HP:0002665) | 1.86736872 |
77 | Ependymoma (HP:0002888) | 1.84896890 |
78 | Cerebral edema (HP:0002181) | 1.83711361 |
79 | Renal Fanconi syndrome (HP:0001994) | 1.83323825 |
80 | Agnosia (HP:0010524) | 1.83119794 |
81 | Meckel diverticulum (HP:0002245) | 1.82723406 |
82 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.82648299 |
83 | Villous atrophy (HP:0011473) | 1.82648299 |
84 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.82093336 |
85 | Abnormality of the ileum (HP:0001549) | 1.78620400 |
86 | Woolly hair (HP:0002224) | 1.78583563 |
87 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.78309592 |
88 | Exercise intolerance (HP:0003546) | 1.78169038 |
89 | Premature ovarian failure (HP:0008209) | 1.76480483 |
90 | Abnormality of the anterior horn cell (HP:0006802) | 1.76241594 |
91 | Degeneration of anterior horn cells (HP:0002398) | 1.76241594 |
92 | Cleft eyelid (HP:0000625) | 1.75151872 |
93 | Abnormality of chromosome stability (HP:0003220) | 1.74966554 |
94 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.73019740 |
95 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.73019740 |
96 | Calcaneovalgus deformity (HP:0001848) | 1.72796773 |
97 | Chronic otitis media (HP:0000389) | 1.69850320 |
98 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.69482706 |
99 | Premature skin wrinkling (HP:0100678) | 1.69453469 |
100 | Abnormality of the calcaneus (HP:0008364) | 1.69286622 |
101 | Tracheoesophageal fistula (HP:0002575) | 1.68185940 |
102 | Type I transferrin isoform profile (HP:0003642) | 1.67889950 |
103 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.67889621 |
104 | Short 4th metacarpal (HP:0010044) | 1.67889621 |
105 | Abnormality of T cell physiology (HP:0011840) | 1.67833766 |
106 | Abnormality of the lacrimal duct (HP:0011481) | 1.67622378 |
107 | Facial cleft (HP:0002006) | 1.67193680 |
108 | Pancytopenia (HP:0001876) | 1.66555509 |
109 | Bicuspid aortic valve (HP:0001647) | 1.66382591 |
110 | Hepatic necrosis (HP:0002605) | 1.63875953 |
111 | Rhabdomyosarcoma (HP:0002859) | 1.63725119 |
112 | Optic nerve coloboma (HP:0000588) | 1.63340925 |
113 | Increased serum lactate (HP:0002151) | 1.62796831 |
114 | Sparse eyelashes (HP:0000653) | 1.61619264 |
115 | Abnormality of cochlea (HP:0000375) | 1.61226555 |
116 | Exertional dyspnea (HP:0002875) | 1.61052708 |
117 | Small intestinal stenosis (HP:0012848) | 1.60642284 |
118 | Duodenal stenosis (HP:0100867) | 1.60642284 |
119 | Lactic acidosis (HP:0003128) | 1.60446907 |
120 | Preauricular skin tag (HP:0000384) | 1.60413403 |
121 | Cellular immunodeficiency (HP:0005374) | 1.60276555 |
122 | Progressive macrocephaly (HP:0004481) | 1.60000412 |
123 | Recurrent bronchitis (HP:0002837) | 1.59431882 |
124 | Abnormality of DNA repair (HP:0003254) | 1.58735959 |
125 | Horseshoe kidney (HP:0000085) | 1.58686783 |
126 | Bone marrow hypocellularity (HP:0005528) | 1.58413609 |
127 | Skin tags (HP:0010609) | 1.57854823 |
128 | Increased hepatocellular lipid droplets (HP:0006565) | 1.57478762 |
129 | Prolonged bleeding time (HP:0003010) | 1.56822000 |
130 | Testicular atrophy (HP:0000029) | 1.56622441 |
131 | Gastrointestinal inflammation (HP:0004386) | 1.55444874 |
132 | Hypertensive crisis (HP:0100735) | 1.55029342 |
133 | Gastrointestinal stroma tumor (HP:0100723) | 1.54174131 |
134 | Pili torti (HP:0003777) | 1.53651096 |
135 | Short thumb (HP:0009778) | 1.53513500 |
136 | Deformed tarsal bones (HP:0008119) | 1.52932758 |
137 | Abnormal lung lobation (HP:0002101) | 1.52826993 |
138 | Metaphyseal cupping (HP:0003021) | 1.52696051 |
139 | Thoracic kyphosis (HP:0002942) | 1.52596467 |
140 | Muscle fiber atrophy (HP:0100295) | 1.52498565 |
141 | Ragged-red muscle fibers (HP:0003200) | 1.51941655 |
142 | Rectal prolapse (HP:0002035) | 1.50980319 |
143 | Partial duplication of the phalanx of hand (HP:0009999) | 1.50280550 |
144 | Abnormality of T cells (HP:0002843) | 1.49988880 |
145 | Respiratory difficulties (HP:0002880) | 1.49858408 |
146 | Neoplasm of the colon (HP:0100273) | 1.49440976 |
147 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.49111118 |
148 | High anterior hairline (HP:0009890) | 1.47417945 |
149 | Delayed cranial suture closure (HP:0000270) | 1.47063195 |
150 | Deep palmar crease (HP:0006191) | 1.45173420 |
151 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.44938546 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NME2 | 4.44135941 |
2 | VRK2 | 4.03586534 |
3 | SMG1 | 3.55682665 |
4 | EEF2K | 3.22108229 |
5 | WEE1 | 3.20318290 |
6 | BUB1 | 2.82776121 |
7 | RPS6KB2 | 2.79161021 |
8 | CDC7 | 2.73176635 |
9 | TGFBR1 | 2.32603782 |
10 | TRIB3 | 2.30576348 |
11 | LRRK2 | 2.17537992 |
12 | PIM2 | 2.17108174 |
13 | MAP4K1 | 2.10866327 |
14 | PRPF4B | 2.00649129 |
15 | FLT3 | 2.00109469 |
16 | NEK2 | 1.93438946 |
17 | TLK1 | 1.91694583 |
18 | PASK | 1.89942994 |
19 | SRPK1 | 1.88179552 |
20 | VRK1 | 1.87740929 |
21 | TAF1 | 1.87078706 |
22 | MAP3K10 | 1.81620290 |
23 | DYRK3 | 1.80829142 |
24 | PBK | 1.76689374 |
25 | CDK7 | 1.76627927 |
26 | ACVR1B | 1.72542382 |
27 | RPS6KA4 | 1.70394694 |
28 | STK16 | 1.69775730 |
29 | EIF2AK1 | 1.68847198 |
30 | PKN2 | 1.49549357 |
31 | MKNK1 | 1.48696067 |
32 | AURKB | 1.46254349 |
33 | BRSK2 | 1.41026392 |
34 | TSSK6 | 1.39333887 |
35 | SCYL2 | 1.34414724 |
36 | BTK | 1.33814530 |
37 | CDK12 | 1.33355246 |
38 | STK10 | 1.33349296 |
39 | ATR | 1.30764372 |
40 | PIM1 | 1.28306417 |
41 | NME1 | 1.26665499 |
42 | EIF2AK3 | 1.26064731 |
43 | CDK4 | 1.23153683 |
44 | PAK4 | 1.14740511 |
45 | PLK1 | 1.12131525 |
46 | KIT | 1.11213555 |
47 | MAP2K3 | 1.11211806 |
48 | TEC | 1.10945011 |
49 | MAPKAPK3 | 1.09728536 |
50 | KDR | 1.07848736 |
51 | ILK | 1.03731205 |
52 | MAP3K8 | 1.03102273 |
53 | TTK | 0.99977270 |
54 | BCKDK | 0.95883822 |
55 | ZAP70 | 0.93614564 |
56 | STK4 | 0.92858825 |
57 | EPHA2 | 0.91787103 |
58 | CDK8 | 0.91076858 |
59 | MST4 | 0.85016307 |
60 | ICK | 0.84800131 |
61 | CSF1R | 0.84796600 |
62 | DAPK3 | 0.83786828 |
63 | BRAF | 0.82185909 |
64 | CHEK2 | 0.79998909 |
65 | CDK6 | 0.78963977 |
66 | CHEK1 | 0.78955239 |
67 | AURKA | 0.76664312 |
68 | JAK3 | 0.76419947 |
69 | ARAF | 0.74799366 |
70 | RPS6KA5 | 0.74044046 |
71 | CSNK2A2 | 0.72554641 |
72 | MKNK2 | 0.72403143 |
73 | IRAK3 | 0.71668730 |
74 | TESK2 | 0.71384451 |
75 | GRK6 | 0.71315512 |
76 | PAK2 | 0.70468501 |
77 | SIK1 | 0.69923295 |
78 | NLK | 0.67608516 |
79 | PLK4 | 0.67603339 |
80 | IKBKB | 0.66892819 |
81 | ZAK | 0.63715263 |
82 | BLK | 0.60890623 |
83 | TYK2 | 0.60746810 |
84 | MAP3K3 | 0.60545306 |
85 | ATM | 0.58560360 |
86 | MAP3K13 | 0.58288651 |
87 | CSNK2A1 | 0.57288492 |
88 | CDK19 | 0.56874373 |
89 | ERN1 | 0.56416066 |
90 | RPS6KL1 | 0.55442447 |
91 | RPS6KC1 | 0.55442447 |
92 | CDK2 | 0.55225743 |
93 | RPS6KA6 | 0.54587274 |
94 | PAK1 | 0.54163098 |
95 | NEK1 | 0.54097810 |
96 | BRD4 | 0.53606497 |
97 | SYK | 0.52904052 |
98 | FGFR4 | 0.52540563 |
99 | PLK3 | 0.51868047 |
100 | PTK6 | 0.50394559 |
101 | MAP3K11 | 0.49897578 |
102 | MATK | 0.47819080 |
103 | AKT2 | 0.45796217 |
104 | TGFBR2 | 0.45402010 |
105 | BRSK1 | 0.44687907 |
106 | LCK | 0.44046446 |
107 | LYN | 0.43420269 |
108 | CHUK | 0.42865224 |
109 | CLK1 | 0.42660810 |
110 | EIF2AK2 | 0.41999089 |
111 | ALK | 0.40646882 |
112 | PRKCI | 0.38639974 |
113 | STK24 | 0.37939484 |
114 | MTOR | 0.36938050 |
115 | MAPKAPK2 | 0.36317813 |
116 | BMX | 0.35833762 |
117 | RPS6KA1 | 0.35788724 |
118 | TBK1 | 0.35036617 |
119 | CDK9 | 0.34844847 |
120 | CDK1 | 0.34680306 |
121 | MAP2K2 | 0.34366942 |
122 | TYRO3 | 0.33717637 |
123 | RAF1 | 0.32502230 |
124 | MELK | 0.31024805 |
125 | DAPK1 | 0.30992928 |
126 | MAPKAPK5 | 0.30481359 |
127 | TAOK2 | 0.29819524 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Ribosome_Homo sapiens_hsa03010 | 6.70092698 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.35495568 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.61966448 |
4 | Spliceosome_Homo sapiens_hsa03040 | 3.04373119 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 2.80320770 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.76566383 |
7 | Base excision repair_Homo sapiens_hsa03410 | 2.62116744 |
8 | Proteasome_Homo sapiens_hsa03050 | 2.58608457 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.51647379 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.48159107 |
11 | RNA transport_Homo sapiens_hsa03013 | 2.41735792 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.21393671 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.12338826 |
14 | Cell cycle_Homo sapiens_hsa04110 | 2.02456916 |
15 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.93521188 |
16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.79372495 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.71178767 |
18 | RNA degradation_Homo sapiens_hsa03018 | 1.67294525 |
19 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.53236997 |
20 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.45830736 |
21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.36530150 |
22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.29590149 |
23 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.25032282 |
24 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.21516665 |
25 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.17149344 |
26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.15694089 |
27 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.12695389 |
28 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.06772964 |
29 | Protein export_Homo sapiens_hsa03060 | 1.05342368 |
30 | Purine metabolism_Homo sapiens_hsa00230 | 0.99543960 |
31 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.97837223 |
32 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.97737587 |
33 | Carbon metabolism_Homo sapiens_hsa01200 | 0.97735255 |
34 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.96599035 |
35 | Sulfur relay system_Homo sapiens_hsa04122 | 0.91075528 |
36 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.90660926 |
37 | HTLV-I infection_Homo sapiens_hsa05166 | 0.83244624 |
38 | Parkinsons disease_Homo sapiens_hsa05012 | 0.82835148 |
39 | Thyroid cancer_Homo sapiens_hsa05216 | 0.81234932 |
40 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.79178342 |
41 | Huntingtons disease_Homo sapiens_hsa05016 | 0.76303131 |
42 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.75425923 |
43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.73493347 |
44 | Measles_Homo sapiens_hsa05162 | 0.69006377 |
45 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.68631402 |
46 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.66139824 |
47 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.65663688 |
48 | Legionellosis_Homo sapiens_hsa05134 | 0.65010322 |
49 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.64451065 |
50 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.64067573 |
51 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.63977613 |
52 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.63468474 |
53 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.63419741 |
54 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.63168855 |
55 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.61127104 |
56 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.60490002 |
57 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.59672776 |
58 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.59061188 |
59 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.58835397 |
60 | Apoptosis_Homo sapiens_hsa04210 | 0.57066970 |
61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.56261020 |
62 | Hepatitis B_Homo sapiens_hsa05161 | 0.55710047 |
63 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.53072448 |
64 | Alcoholism_Homo sapiens_hsa05034 | 0.52291883 |
65 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.52280002 |
66 | Bladder cancer_Homo sapiens_hsa05219 | 0.51084676 |
67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.50987811 |
68 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.49981815 |
69 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.49589866 |
70 | Leishmaniasis_Homo sapiens_hsa05140 | 0.49253439 |
71 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.47587873 |
72 | Shigellosis_Homo sapiens_hsa05131 | 0.47405623 |
73 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.47204867 |
74 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.47051019 |
75 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46493126 |
76 | Colorectal cancer_Homo sapiens_hsa05210 | 0.45693380 |
77 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45409679 |
78 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.43836271 |
79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42946092 |
80 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.42475105 |
81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.40844847 |
82 | Pathways in cancer_Homo sapiens_hsa05200 | 0.40829816 |
83 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.40143518 |
84 | Viral myocarditis_Homo sapiens_hsa05416 | 0.39632140 |
85 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.39590284 |
86 | Asthma_Homo sapiens_hsa05310 | 0.39145643 |
87 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.37418333 |
88 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.35751902 |
89 | Influenza A_Homo sapiens_hsa05164 | 0.35178803 |
90 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.35107491 |
91 | Allograft rejection_Homo sapiens_hsa05330 | 0.35103521 |
92 | Galactose metabolism_Homo sapiens_hsa00052 | 0.34905612 |
93 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.34448152 |
94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.34297400 |
95 | Metabolic pathways_Homo sapiens_hsa01100 | 0.32841720 |
96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.32635699 |
97 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.32548815 |
98 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.32159794 |
99 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.31806816 |
100 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.30300796 |
101 | Prostate cancer_Homo sapiens_hsa05215 | 0.29729725 |
102 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.29485133 |
103 | Alzheimers disease_Homo sapiens_hsa05010 | 0.29368026 |
104 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.29155777 |
105 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.28941653 |
106 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.27476131 |
107 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.27307929 |
108 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.26887287 |
109 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.25461476 |
110 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.25355639 |
111 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.24950032 |
112 | Platelet activation_Homo sapiens_hsa04611 | 0.24885197 |
113 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.24614237 |
114 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.24123081 |
115 | Endometrial cancer_Homo sapiens_hsa05213 | 0.24087085 |
116 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.23891555 |
117 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.22184333 |
118 | Adherens junction_Homo sapiens_hsa04520 | 0.21821199 |
119 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.19892747 |
120 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.17359009 |
121 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.16317272 |
122 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.16187235 |