

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.23725462 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 5.20952665 |
| 3 | viral transcription (GO:0019083) | 5.20681539 |
| 4 | translational termination (GO:0006415) | 4.99825986 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.98354602 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 4.98354602 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.62493108 |
| 8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.55998684 |
| 9 | behavioral response to nicotine (GO:0035095) | 4.53830136 |
| 10 | translational elongation (GO:0006414) | 4.49567843 |
| 11 | protein targeting to ER (GO:0045047) | 4.47608979 |
| 12 | cotranslational protein targeting to membrane (GO:0006613) | 4.46791558 |
| 13 | protein neddylation (GO:0045116) | 4.33288289 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.27724651 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 4.27344660 |
| 16 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.25950426 |
| 17 | regulation of regulatory T cell differentiation (GO:0045589) | 4.20129713 |
| 18 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.14635052 |
| 19 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.14635052 |
| 20 | ribosomal small subunit biogenesis (GO:0042274) | 4.09263168 |
| 21 | maturation of SSU-rRNA (GO:0030490) | 4.00729780 |
| 22 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.97696452 |
| 23 | viral life cycle (GO:0019058) | 3.75024467 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.74159786 |
| 25 | cytidine metabolic process (GO:0046087) | 3.71503770 |
| 26 | cytidine catabolic process (GO:0006216) | 3.71503770 |
| 27 | cytidine deamination (GO:0009972) | 3.71503770 |
| 28 | cellular protein complex disassembly (GO:0043624) | 3.67304138 |
| 29 | regulation of immunoglobulin secretion (GO:0051023) | 3.60614804 |
| 30 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.55509977 |
| 31 | positive regulation of defense response to virus by host (GO:0002230) | 3.44571430 |
| 32 | GTP biosynthetic process (GO:0006183) | 3.44459930 |
| 33 | electron transport chain (GO:0022900) | 3.40778224 |
| 34 | ribosomal large subunit biogenesis (GO:0042273) | 3.39772542 |
| 35 | respiratory electron transport chain (GO:0022904) | 3.39766227 |
| 36 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.37834751 |
| 37 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.37466576 |
| 38 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.33710717 |
| 39 | translational initiation (GO:0006413) | 3.31860671 |
| 40 | translation (GO:0006412) | 3.28143172 |
| 41 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.24355255 |
| 42 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.23796088 |
| 43 | termination of RNA polymerase III transcription (GO:0006386) | 3.23568611 |
| 44 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.23568611 |
| 45 | mannosylation (GO:0097502) | 3.13894485 |
| 46 | protein-cofactor linkage (GO:0018065) | 3.13609674 |
| 47 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.13561216 |
| 48 | cellular response to interleukin-15 (GO:0071350) | 3.11547064 |
| 49 | protein complex biogenesis (GO:0070271) | 3.06023838 |
| 50 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.04299860 |
| 51 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.03873119 |
| 52 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.03382359 |
| 53 | signal peptide processing (GO:0006465) | 3.03358104 |
| 54 | regulation of chronic inflammatory response (GO:0002676) | 3.00149743 |
| 55 | mast cell activation (GO:0045576) | 2.98932293 |
| 56 | protein complex disassembly (GO:0043241) | 2.97107896 |
| 57 | protein targeting to membrane (GO:0006612) | 2.91790997 |
| 58 | ATP biosynthetic process (GO:0006754) | 2.90410495 |
| 59 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.88880404 |
| 60 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.86576666 |
| 61 | macromolecular complex disassembly (GO:0032984) | 2.85658948 |
| 62 | GPI anchor metabolic process (GO:0006505) | 2.85451494 |
| 63 | metallo-sulfur cluster assembly (GO:0031163) | 2.81645319 |
| 64 | iron-sulfur cluster assembly (GO:0016226) | 2.81645319 |
| 65 | hydrogen ion transmembrane transport (GO:1902600) | 2.78888806 |
| 66 | positive regulation of prostaglandin secretion (GO:0032308) | 2.77372161 |
| 67 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.76885382 |
| 68 | UTP biosynthetic process (GO:0006228) | 2.74790024 |
| 69 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.74531954 |
| 70 | pseudouridine synthesis (GO:0001522) | 2.70502520 |
| 71 | positive regulation of fatty acid transport (GO:2000193) | 2.67667606 |
| 72 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.67446986 |
| 73 | proton transport (GO:0015992) | 2.66995507 |
| 74 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.66233946 |
| 75 | NADH dehydrogenase complex assembly (GO:0010257) | 2.66233946 |
| 76 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.66233946 |
| 77 | tRNA processing (GO:0008033) | 2.64382776 |
| 78 | respiratory chain complex IV assembly (GO:0008535) | 2.64283267 |
| 79 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.63069967 |
| 80 | hydrogen transport (GO:0006818) | 2.62432221 |
| 81 | GPI anchor biosynthetic process (GO:0006506) | 2.61439963 |
| 82 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.60153150 |
| 83 | mRNA catabolic process (GO:0006402) | 2.59707667 |
| 84 | response to pheromone (GO:0019236) | 2.57088033 |
| 85 | fucose catabolic process (GO:0019317) | 2.56587348 |
| 86 | L-fucose metabolic process (GO:0042354) | 2.56587348 |
| 87 | L-fucose catabolic process (GO:0042355) | 2.56587348 |
| 88 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.55759134 |
| 89 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.55005076 |
| 90 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.52990317 |
| 91 | tolerance induction (GO:0002507) | 2.52752906 |
| 92 | positive regulation of humoral immune response (GO:0002922) | 2.51000218 |
| 93 | proteasome assembly (GO:0043248) | 2.50041610 |
| 94 | cellular component biogenesis (GO:0044085) | 2.49747780 |
| 95 | chaperone-mediated protein transport (GO:0072321) | 2.47181140 |
| 96 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.46501751 |
| 97 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.46415493 |
| 98 | kynurenine metabolic process (GO:0070189) | 2.46388668 |
| 99 | positive regulation of cell killing (GO:0031343) | 2.46265421 |
| 100 | negative T cell selection (GO:0043383) | 2.45851123 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.16432385 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.05861239 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.88656218 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.47742756 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.25582602 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.97439926 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.80803543 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.74816067 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.66732840 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.53598714 |
| 11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.43893967 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.42274870 |
| 13 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.35366489 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.31019505 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.29111538 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.04186974 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.01969572 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.00256937 |
| 19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.97523175 |
| 20 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.95904542 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.92892235 |
| 22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.86745638 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.81168198 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.75812587 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.72195924 |
| 26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.71482258 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.66509471 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.62348551 |
| 29 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.58852782 |
| 30 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.56495447 |
| 31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.54067184 |
| 32 | GATA3_26560356_Chip-Seq_TH2_Human | 1.51709536 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.51297265 |
| 34 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.50820273 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.44014601 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.39608261 |
| 37 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.37474032 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.33970505 |
| 39 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.33448009 |
| 40 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.31623797 |
| 41 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.29026380 |
| 42 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.28829042 |
| 43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27707760 |
| 44 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.27486452 |
| 45 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.27041054 |
| 46 | AR_20517297_ChIP-Seq_VCAP_Human | 1.25413936 |
| 47 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.23002967 |
| 48 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.22063072 |
| 49 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21895491 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20338604 |
| 51 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20338604 |
| 52 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.19971390 |
| 53 | MYB_26560356_Chip-Seq_TH2_Human | 1.19912198 |
| 54 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.19743171 |
| 55 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.19142358 |
| 56 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.17846104 |
| 57 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.17466485 |
| 58 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.16167742 |
| 59 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15919635 |
| 60 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14795352 |
| 61 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.13891502 |
| 62 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13701131 |
| 63 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.12391641 |
| 64 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.11548183 |
| 65 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10401866 |
| 66 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10126515 |
| 67 | ERA_21632823_ChIP-Seq_H3396_Human | 1.09761401 |
| 68 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.09313238 |
| 69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.06957820 |
| 70 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.03520847 |
| 71 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.03315335 |
| 72 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02648972 |
| 73 | EWS_26573619_Chip-Seq_HEK293_Human | 1.02283522 |
| 74 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.02124302 |
| 75 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.02076869 |
| 76 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01526752 |
| 77 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01356132 |
| 78 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.01214737 |
| 79 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.01161615 |
| 80 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.00470075 |
| 81 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00449141 |
| 82 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.99962903 |
| 83 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.99597200 |
| 84 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.99535607 |
| 85 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99535127 |
| 86 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.98922436 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.98463641 |
| 88 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.98463641 |
| 89 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.97135613 |
| 90 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.96146435 |
| 91 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94841347 |
| 92 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.94539702 |
| 93 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93352890 |
| 94 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.92952237 |
| 95 | P300_27268052_Chip-Seq_Bcells_Human | 0.92891792 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92053592 |
| 97 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.92007745 |
| 98 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.91593635 |
| 99 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.91534356 |
| 100 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.91083215 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.26435693 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.04949355 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.04024814 |
| 4 | MP0003646_muscle_fatigue | 2.30988251 |
| 5 | MP0006292_abnormal_olfactory_placode | 2.30021531 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.15731994 |
| 7 | MP0001968_abnormal_touch/_nociception | 2.15030561 |
| 8 | MP0001873_stomach_inflammation | 2.10775888 |
| 9 | MP0002736_abnormal_nociception_after | 2.10254599 |
| 10 | MP0005645_abnormal_hypothalamus_physiol | 2.09299302 |
| 11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.01496500 |
| 12 | MP0009785_altered_susceptibility_to | 1.98470525 |
| 13 | MP0001800_abnormal_humoral_immune | 1.95691540 |
| 14 | MP0005646_abnormal_pituitary_gland | 1.93678377 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 1.91370680 |
| 16 | MP0008872_abnormal_physiological_respon | 1.89202567 |
| 17 | MP0001790_abnormal_immune_system | 1.84813715 |
| 18 | MP0005387_immune_system_phenotype | 1.84813715 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 1.84106999 |
| 20 | MP0002163_abnormal_gland_morphology | 1.83685959 |
| 21 | MP0005000_abnormal_immune_tolerance | 1.79776834 |
| 22 | MP0002148_abnormal_hypersensitivity_rea | 1.77423408 |
| 23 | MP0004142_abnormal_muscle_tone | 1.76974180 |
| 24 | MP0000685_abnormal_immune_system | 1.75457988 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.71801974 |
| 26 | MP0004145_abnormal_muscle_electrophysio | 1.70154247 |
| 27 | MP0003787_abnormal_imprinting | 1.65314785 |
| 28 | MP0009333_abnormal_splenocyte_physiolog | 1.65055965 |
| 29 | MP0004147_increased_porphyrin_level | 1.62663676 |
| 30 | MP0005551_abnormal_eye_electrophysiolog | 1.61176435 |
| 31 | MP0002723_abnormal_immune_serum | 1.58878885 |
| 32 | MP0002837_dystrophic_cardiac_calcinosis | 1.58436933 |
| 33 | MP0003763_abnormal_thymus_physiology | 1.53910967 |
| 34 | MP0002102_abnormal_ear_morphology | 1.50313659 |
| 35 | MP0001819_abnormal_immune_cell | 1.45192649 |
| 36 | MP0002420_abnormal_adaptive_immunity | 1.45091665 |
| 37 | MP0001986_abnormal_taste_sensitivity | 1.43191914 |
| 38 | MP0003436_decreased_susceptibility_to | 1.39981450 |
| 39 | MP0009764_decreased_sensitivity_to | 1.39755116 |
| 40 | MP0003011_delayed_dark_adaptation | 1.36691845 |
| 41 | MP0002166_altered_tumor_susceptibility | 1.35301539 |
| 42 | MP0002452_abnormal_antigen_presenting | 1.32591164 |
| 43 | MP0005075_abnormal_melanosome_morpholog | 1.32110291 |
| 44 | MP0010155_abnormal_intestine_physiology | 1.30861130 |
| 45 | MP0005025_abnormal_response_to | 1.29441213 |
| 46 | MP0003878_abnormal_ear_physiology | 1.27882029 |
| 47 | MP0005377_hearing/vestibular/ear_phenot | 1.27882029 |
| 48 | MP0003724_increased_susceptibility_to | 1.25166885 |
| 49 | MP0002933_joint_inflammation | 1.24058427 |
| 50 | MP0003866_abnormal_defecation | 1.22537447 |
| 51 | MP0002653_abnormal_ependyma_morphology | 1.20996617 |
| 52 | MP0003195_calcinosis | 1.19967189 |
| 53 | MP0008995_early_reproductive_senescence | 1.18144311 |
| 54 | MP0002876_abnormal_thyroid_physiology | 1.17728250 |
| 55 | MP0004885_abnormal_endolymph | 1.16953452 |
| 56 | MP0002006_tumorigenesis | 1.16092136 |
| 57 | MP0003806_abnormal_nucleotide_metabolis | 1.15688957 |
| 58 | MP0005379_endocrine/exocrine_gland_phen | 1.15162882 |
| 59 | MP0003786_premature_aging | 1.15140691 |
| 60 | MP0001501_abnormal_sleep_pattern | 1.13428539 |
| 61 | MP0005084_abnormal_gallbladder_morpholo | 1.12803209 |
| 62 | MP0005253_abnormal_eye_physiology | 1.10797542 |
| 63 | MP0002638_abnormal_pupillary_reflex | 1.01998893 |
| 64 | MP0001845_abnormal_inflammatory_respons | 1.01524442 |
| 65 | MP0000716_abnormal_immune_system | 1.00239992 |
| 66 | MP0002095_abnormal_skin_pigmentation | 0.99748363 |
| 67 | MP0001485_abnormal_pinna_reflex | 0.99238691 |
| 68 | MP0003880_abnormal_central_pattern | 0.99149126 |
| 69 | MP0002405_respiratory_system_inflammati | 0.97806694 |
| 70 | MP0002277_abnormal_respiratory_mucosa | 0.97223899 |
| 71 | MP0002272_abnormal_nervous_system | 0.97028337 |
| 72 | MP0002398_abnormal_bone_marrow | 0.94034357 |
| 73 | MP0008789_abnormal_olfactory_epithelium | 0.93705197 |
| 74 | MP0000631_abnormal_neuroendocrine_gland | 0.92790894 |
| 75 | MP0005410_abnormal_fertilization | 0.91392261 |
| 76 | MP0000703_abnormal_thymus_morphology | 0.91116787 |
| 77 | MP0000689_abnormal_spleen_morphology | 0.90924888 |
| 78 | MP0006036_abnormal_mitochondrial_physio | 0.88586897 |
| 79 | MP0005360_urolithiasis | 0.87829527 |
| 80 | MP0001919_abnormal_reproductive_system | 0.87787359 |
| 81 | MP0001984_abnormal_olfaction | 0.87751237 |
| 82 | MP0005389_reproductive_system_phenotype | 0.86171231 |
| 83 | MP0002234_abnormal_pharynx_morphology | 0.85903990 |
| 84 | MP0005636_abnormal_mineral_homeostasis | 0.85802613 |
| 85 | MP0003121_genomic_imprinting | 0.82996817 |
| 86 | MP0001905_abnormal_dopamine_level | 0.81679409 |
| 87 | MP0009745_abnormal_behavioral_response | 0.80545525 |
| 88 | MP0008058_abnormal_DNA_repair | 0.80014181 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.79842474 |
| 90 | MP0001970_abnormal_pain_threshold | 0.79223446 |
| 91 | MP0002722_abnormal_immune_system | 0.78836515 |
| 92 | MP0001529_abnormal_vocalization | 0.78307234 |
| 93 | MP0002429_abnormal_blood_cell | 0.77709680 |
| 94 | MP0001663_abnormal_digestive_system | 0.77235099 |
| 95 | MP0006276_abnormal_autonomic_nervous | 0.76934138 |
| 96 | MP0003718_maternal_effect | 0.74441447 |
| 97 | MP0003122_maternal_imprinting | 0.74270897 |
| 98 | MP0004133_heterotaxia | 0.71389406 |
| 99 | MP0001486_abnormal_startle_reflex | 0.70607299 |
| 100 | MP0004742_abnormal_vestibular_system | 0.69564083 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.10485397 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 4.02885952 |
| 3 | IgG deficiency (HP:0004315) | 4.00274853 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.95297528 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.83518209 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.71464316 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.68974585 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.50423791 |
| 9 | Type II lissencephaly (HP:0007260) | 3.45757672 |
| 10 | Increased CSF lactate (HP:0002490) | 3.44452679 |
| 11 | Pancreatic cysts (HP:0001737) | 3.44054344 |
| 12 | Acute encephalopathy (HP:0006846) | 3.43022566 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.30993569 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.25633847 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 3.17890696 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.17890696 |
| 17 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.17517834 |
| 18 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.17327091 |
| 19 | Increased intramyocellular lipid droplets (HP:0012240) | 3.17302659 |
| 20 | Reticulocytopenia (HP:0001896) | 3.12047282 |
| 21 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.06328705 |
| 22 | Pancreatic fibrosis (HP:0100732) | 3.02321449 |
| 23 | Congenital, generalized hypertrichosis (HP:0004540) | 2.96012233 |
| 24 | Congenital stationary night blindness (HP:0007642) | 2.86160481 |
| 25 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.85370736 |
| 26 | Hepatocellular necrosis (HP:0001404) | 2.80750822 |
| 27 | Exertional dyspnea (HP:0002875) | 2.80017614 |
| 28 | Pendular nystagmus (HP:0012043) | 2.75058423 |
| 29 | Nephronophthisis (HP:0000090) | 2.74587663 |
| 30 | Renal cortical cysts (HP:0000803) | 2.72547912 |
| 31 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.72434693 |
| 32 | Increased muscle lipid content (HP:0009058) | 2.70456722 |
| 33 | Abnormality of the renal cortex (HP:0011035) | 2.70379571 |
| 34 | Stomatitis (HP:0010280) | 2.64733059 |
| 35 | Abnormal number of erythroid precursors (HP:0012131) | 2.62893172 |
| 36 | Optic disc pallor (HP:0000543) | 2.57666726 |
| 37 | Asplenia (HP:0001746) | 2.56002095 |
| 38 | Medial flaring of the eyebrow (HP:0010747) | 2.53618274 |
| 39 | Increased IgM level (HP:0003496) | 2.52834598 |
| 40 | Cerebral edema (HP:0002181) | 2.52553467 |
| 41 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.51622801 |
| 42 | True hermaphroditism (HP:0010459) | 2.49856190 |
| 43 | Hepatic necrosis (HP:0002605) | 2.42990421 |
| 44 | Abnormality of the pons (HP:0007361) | 2.40402564 |
| 45 | Aplastic anemia (HP:0001915) | 2.37532923 |
| 46 | Macrocytic anemia (HP:0001972) | 2.37429592 |
| 47 | Increased serum lactate (HP:0002151) | 2.35317779 |
| 48 | Severe combined immunodeficiency (HP:0004430) | 2.34811897 |
| 49 | Abnormality of T cells (HP:0002843) | 2.32583819 |
| 50 | Decreased central vision (HP:0007663) | 2.31519367 |
| 51 | Attenuation of retinal blood vessels (HP:0007843) | 2.30543882 |
| 52 | Abnormal drinking behavior (HP:0030082) | 2.30374868 |
| 53 | Polydipsia (HP:0001959) | 2.30374868 |
| 54 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.27298721 |
| 55 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.27298721 |
| 56 | Increased corneal curvature (HP:0100692) | 2.25232841 |
| 57 | Keratoconus (HP:0000563) | 2.25232841 |
| 58 | Abnormality of T cell physiology (HP:0011840) | 2.25009212 |
| 59 | Abnormality of the renal medulla (HP:0100957) | 2.22642388 |
| 60 | Abnormality of renal resorption (HP:0011038) | 2.21694108 |
| 61 | Lactic acidosis (HP:0003128) | 2.19878508 |
| 62 | Abolished electroretinogram (ERG) (HP:0000550) | 2.14811334 |
| 63 | Abnormality of the prostate (HP:0008775) | 2.12497717 |
| 64 | Cerebellar dysplasia (HP:0007033) | 2.12205322 |
| 65 | Hypoproteinemia (HP:0003075) | 2.09933765 |
| 66 | Pallor (HP:0000980) | 2.09834865 |
| 67 | Bile duct proliferation (HP:0001408) | 2.07857103 |
| 68 | Abnormal biliary tract physiology (HP:0012439) | 2.07857103 |
| 69 | Respiratory difficulties (HP:0002880) | 2.07064785 |
| 70 | Hypoplasia of the pons (HP:0012110) | 2.02604433 |
| 71 | T lymphocytopenia (HP:0005403) | 2.01807110 |
| 72 | Methylmalonic acidemia (HP:0002912) | 2.01336205 |
| 73 | Type 2 muscle fiber atrophy (HP:0003554) | 2.00957467 |
| 74 | Prostate neoplasm (HP:0100787) | 2.00838865 |
| 75 | Hyperphosphaturia (HP:0003109) | 2.00002979 |
| 76 | Abnormality of urine glucose concentration (HP:0011016) | 1.99769782 |
| 77 | Glycosuria (HP:0003076) | 1.99769782 |
| 78 | Hyperglycinemia (HP:0002154) | 1.99063571 |
| 79 | Concave nail (HP:0001598) | 1.99043810 |
| 80 | Pancytopenia (HP:0001876) | 1.98294986 |
| 81 | Panhypogammaglobulinemia (HP:0003139) | 1.96342141 |
| 82 | Cystic liver disease (HP:0006706) | 1.95753251 |
| 83 | Methylmalonic aciduria (HP:0012120) | 1.92063849 |
| 84 | Postaxial foot polydactyly (HP:0001830) | 1.89665850 |
| 85 | Sclerocornea (HP:0000647) | 1.87644842 |
| 86 | Leukodystrophy (HP:0002415) | 1.87244652 |
| 87 | Lethargy (HP:0001254) | 1.85072047 |
| 88 | Absent thumb (HP:0009777) | 1.83722716 |
| 89 | Abnormality of T cell number (HP:0011839) | 1.83529927 |
| 90 | Muscle fiber atrophy (HP:0100295) | 1.83243378 |
| 91 | Polyuria (HP:0000103) | 1.83079385 |
| 92 | Exercise intolerance (HP:0003546) | 1.82497975 |
| 93 | Abnormality of the renal collecting system (HP:0004742) | 1.79581650 |
| 94 | Thyroiditis (HP:0100646) | 1.78771071 |
| 95 | Anencephaly (HP:0002323) | 1.77168740 |
| 96 | Abnormality of DNA repair (HP:0003254) | 1.74565511 |
| 97 | Severe muscular hypotonia (HP:0006829) | 1.73365820 |
| 98 | Parakeratosis (HP:0001036) | 1.73268001 |
| 99 | Lissencephaly (HP:0001339) | 1.73139114 |
| 100 | Recurrent cutaneous fungal infections (HP:0011370) | 1.69611091 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.74758280 |
| 2 | TLK1 | 4.35010677 |
| 3 | ZAK | 3.96786821 |
| 4 | MAP4K2 | 3.49479558 |
| 5 | WNK4 | 2.77971216 |
| 6 | ADRBK2 | 2.77618709 |
| 7 | MAP4K1 | 2.59525792 |
| 8 | CDK19 | 2.07206253 |
| 9 | GRK1 | 1.98717480 |
| 10 | BCKDK | 1.93408181 |
| 11 | NUAK1 | 1.92580825 |
| 12 | NME2 | 1.86845413 |
| 13 | TAOK3 | 1.80553063 |
| 14 | VRK2 | 1.78615852 |
| 15 | ITK | 1.67371982 |
| 16 | GRK6 | 1.65462673 |
| 17 | KDR | 1.62999673 |
| 18 | IKBKB | 1.62584569 |
| 19 | STK39 | 1.49385592 |
| 20 | OXSR1 | 1.43759261 |
| 21 | MAP3K12 | 1.43059478 |
| 22 | VRK1 | 1.39836611 |
| 23 | TEC | 1.38842492 |
| 24 | CAMKK2 | 1.36494370 |
| 25 | SYK | 1.25002830 |
| 26 | PRKCQ | 1.24744954 |
| 27 | NME1 | 1.23494650 |
| 28 | TRIM28 | 1.22498927 |
| 29 | BMPR2 | 1.10302078 |
| 30 | BTK | 1.08599086 |
| 31 | WNK3 | 1.05666533 |
| 32 | INSRR | 0.99314837 |
| 33 | FRK | 0.98855780 |
| 34 | TNIK | 0.97657724 |
| 35 | TIE1 | 0.96231200 |
| 36 | PINK1 | 0.92385537 |
| 37 | FES | 0.91979299 |
| 38 | LCK | 0.91948296 |
| 39 | MAP2K2 | 0.91373703 |
| 40 | ADRBK1 | 0.90152652 |
| 41 | LIMK1 | 0.88808207 |
| 42 | MYLK | 0.86277902 |
| 43 | LRRK2 | 0.86189001 |
| 44 | BMPR1B | 0.85813217 |
| 45 | PASK | 0.85723436 |
| 46 | DYRK2 | 0.85721006 |
| 47 | PHKG2 | 0.85670369 |
| 48 | PHKG1 | 0.85670369 |
| 49 | LYN | 0.84909282 |
| 50 | TNK2 | 0.84801217 |
| 51 | IKBKE | 0.80267896 |
| 52 | RPS6KA5 | 0.79124437 |
| 53 | STK16 | 0.75478593 |
| 54 | NEK1 | 0.75138174 |
| 55 | PIM1 | 0.74406783 |
| 56 | MAP2K6 | 0.72143691 |
| 57 | GRK7 | 0.71538831 |
| 58 | KIT | 0.71013036 |
| 59 | PIK3CG | 0.66928356 |
| 60 | MAP3K11 | 0.65537519 |
| 61 | EIF2AK2 | 0.53481739 |
| 62 | EIF2AK3 | 0.53449608 |
| 63 | CAMKK1 | 0.53421372 |
| 64 | PAK3 | 0.51726455 |
| 65 | OBSCN | 0.49913756 |
| 66 | PRKCG | 0.49600686 |
| 67 | CASK | 0.48917728 |
| 68 | PRKACA | 0.48569027 |
| 69 | DAPK1 | 0.48300358 |
| 70 | MUSK | 0.47745616 |
| 71 | IGF1R | 0.47480388 |
| 72 | MAPK13 | 0.46664690 |
| 73 | CSNK2A2 | 0.46030809 |
| 74 | ZAP70 | 0.45781675 |
| 75 | PRKCA | 0.45761898 |
| 76 | TESK2 | 0.44307837 |
| 77 | MST4 | 0.43847714 |
| 78 | CAMK1 | 0.43495101 |
| 79 | CSNK2A1 | 0.41712688 |
| 80 | DAPK3 | 0.39494730 |
| 81 | DAPK2 | 0.37999615 |
| 82 | TSSK6 | 0.37486003 |
| 83 | MAP3K4 | 0.37385144 |
| 84 | PDK2 | 0.36776587 |
| 85 | JAK1 | 0.36265097 |
| 86 | CAMK2A | 0.36189277 |
| 87 | CSK | 0.36030849 |
| 88 | TBK1 | 0.35331544 |
| 89 | ERBB3 | 0.34339913 |
| 90 | CSNK1G3 | 0.33670474 |
| 91 | RPS6KA4 | 0.33413058 |
| 92 | GRK5 | 0.33051920 |
| 93 | CSF1R | 0.32676013 |
| 94 | CSNK1A1 | 0.31997385 |
| 95 | MAPKAPK3 | 0.31364217 |
| 96 | RPS6KA6 | 0.29413805 |
| 97 | PIK3CA | 0.29222638 |
| 98 | BUB1 | 0.28395053 |
| 99 | PLK2 | 0.27534836 |
| 100 | AURKB | 0.27488161 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.55107440 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.53470137 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.03250118 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.97996560 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.88250728 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.77880009 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.74253788 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.70539392 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.57778980 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.45097155 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.29405998 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25633529 |
| 13 | Protein export_Homo sapiens_hsa03060 | 2.11989585 |
| 14 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.93868699 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.89557021 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.89452748 |
| 17 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.88469534 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.87995066 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.87698212 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.85848565 |
| 21 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.83756679 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.77057384 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.71674827 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.49554693 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.47312478 |
| 26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.34821161 |
| 27 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.33075784 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.29177029 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.28398288 |
| 30 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.25747071 |
| 31 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.23000847 |
| 32 | Sulfur relay system_Homo sapiens_hsa04122 | 1.21450953 |
| 33 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19898274 |
| 34 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.18814574 |
| 35 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.18331724 |
| 36 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.16750624 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.08198985 |
| 38 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.05521058 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.97916244 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.96606998 |
| 41 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.95921621 |
| 42 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93936398 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.93866803 |
| 44 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.90608523 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.88159980 |
| 46 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.87492478 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.83965528 |
| 48 | Basal transcription factors_Homo sapiens_hsa03022 | 0.81435794 |
| 49 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.79866834 |
| 50 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.79245395 |
| 51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.78026731 |
| 52 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.77804065 |
| 53 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.76488732 |
| 54 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.73397002 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.72998491 |
| 56 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.69365516 |
| 57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.68241031 |
| 58 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67759672 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65204699 |
| 60 | Spliceosome_Homo sapiens_hsa03040 | 0.64791315 |
| 61 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.64076566 |
| 62 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.62480114 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62237915 |
| 64 | Viral myocarditis_Homo sapiens_hsa05416 | 0.62141866 |
| 65 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61348069 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.59465304 |
| 67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58251226 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58048975 |
| 69 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55912055 |
| 70 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.53979880 |
| 71 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.53869450 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50901078 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.50770777 |
| 74 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.50079579 |
| 75 | Nicotine addiction_Homo sapiens_hsa05033 | 0.49627084 |
| 76 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.48927398 |
| 77 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.46535993 |
| 78 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.46519624 |
| 79 | RNA transport_Homo sapiens_hsa03013 | 0.44774233 |
| 80 | Morphine addiction_Homo sapiens_hsa05032 | 0.44308830 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43590035 |
| 82 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41894686 |
| 83 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.40065021 |
| 84 | Taste transduction_Homo sapiens_hsa04742 | 0.39416175 |
| 85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37456770 |
| 86 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.37353685 |
| 87 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.35403099 |
| 88 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.34343759 |
| 89 | Measles_Homo sapiens_hsa05162 | 0.33388194 |
| 90 | Mineral absorption_Homo sapiens_hsa04978 | 0.30283611 |
| 91 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.29982776 |
| 92 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.29266475 |
| 93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.28299458 |
| 94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25645837 |
| 95 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25529550 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.25064719 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.24817966 |
| 98 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.24363010 |
| 99 | Salivary secretion_Homo sapiens_hsa04970 | 0.24232055 |
| 100 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.23677245 |

