RPL12P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)8.39005195
2viral transcription (GO:0019083)7.93675232
3ribosomal small subunit biogenesis (GO:0042274)7.72513189
4translational termination (GO:0006415)7.58265289
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.63236517
6cotranslational protein targeting to membrane (GO:0006613)6.56303597
7maturation of SSU-rRNA (GO:0030490)6.55366721
8protein targeting to ER (GO:0045047)6.50928615
9ATP synthesis coupled proton transport (GO:0015986)6.50301658
10energy coupled proton transport, down electrochemical gradient (GO:0015985)6.50301658
11mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.36421858
12translational elongation (GO:0006414)6.33122129
13establishment of protein localization to endoplasmic reticulum (GO:0072599)6.26264285
14protein localization to endoplasmic reticulum (GO:0070972)6.13587901
15viral life cycle (GO:0019058)5.80878639
16cellular protein complex disassembly (GO:0043624)5.72542187
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.50701012
18behavioral response to nicotine (GO:0035095)5.17393418
19translational initiation (GO:0006413)5.07985739
20chaperone-mediated protein transport (GO:0072321)4.99067438
21establishment of protein localization to mitochondrial membrane (GO:0090151)4.83888170
22protein complex disassembly (GO:0043241)4.74141933
23macromolecular complex disassembly (GO:0032984)4.49656703
24ribosomal large subunit biogenesis (GO:0042273)4.43751486
25protein neddylation (GO:0045116)4.41317157
26respiratory electron transport chain (GO:0022904)4.37536577
27electron transport chain (GO:0022900)4.32331875
28protein targeting to membrane (GO:0006612)4.31461802
29translation (GO:0006412)4.28811058
30inner mitochondrial membrane organization (GO:0007007)4.27103342
31mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.19873966
32nuclear-transcribed mRNA catabolic process (GO:0000956)4.06031660
33negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.94127090
34protein complex biogenesis (GO:0070271)3.94026897
35mRNA catabolic process (GO:0006402)3.88122778
36GTP biosynthetic process (GO:0006183)3.81095228
37DNA deamination (GO:0045006)3.73060211
38ribonucleoprotein complex biogenesis (GO:0022613)3.72309405
39nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.71519516
40regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.66235105
41mitochondrial respiratory chain complex I assembly (GO:0032981)3.63100894
42NADH dehydrogenase complex assembly (GO:0010257)3.63100894
43mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.63100894
44RNA catabolic process (GO:0006401)3.61774410
45protein-cofactor linkage (GO:0018065)3.61277786
46tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.60142221
47RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.60142221
48mitochondrial respiratory chain complex assembly (GO:0033108)3.59785560
49cellular component biogenesis (GO:0044085)3.57489752
50positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.57068476
51termination of RNA polymerase III transcription (GO:0006386)3.51987213
52transcription elongation from RNA polymerase III promoter (GO:0006385)3.51987213
53exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.47749648
54purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.46591054
55purine nucleoside triphosphate biosynthetic process (GO:0009145)3.37042544
56ATP biosynthetic process (GO:0006754)3.35694999
57UTP biosynthetic process (GO:0006228)3.35660875
58hydrogen ion transmembrane transport (GO:1902600)3.30158154
59negative regulation of DNA-templated transcription, elongation (GO:0032785)3.27393217
60regulation of mesoderm development (GO:2000380)3.25984365
61water-soluble vitamin biosynthetic process (GO:0042364)3.15351924
62rRNA processing (GO:0006364)3.14916828
63rRNA metabolic process (GO:0016072)3.13640338
64neuron fate determination (GO:0048664)3.09155144
65UTP metabolic process (GO:0046051)3.07241353
66proton transport (GO:0015992)3.05084078
67hydrogen transport (GO:0006818)3.01465848
68ribonucleoside triphosphate biosynthetic process (GO:0009201)2.98933545
69regulation of isotype switching to IgG isotypes (GO:0048302)2.97335524
70endoderm formation (GO:0001706)2.96923049
71establishment of protein localization to membrane (GO:0090150)2.94813176
72regulation of mitochondrial translation (GO:0070129)2.91155181
73negative regulation of B cell apoptotic process (GO:0002903)2.88288871
74tongue development (GO:0043586)2.85608155
75protein targeting (GO:0006605)2.84221485
76regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.82946084
77regulation of immunoglobulin secretion (GO:0051023)2.81551390
78establishment of protein localization to mitochondrion (GO:0072655)2.72998439
79rRNA modification (GO:0000154)2.72769121
80response to xenobiotic stimulus (GO:0009410)2.69727497
81establishment of protein localization to organelle (GO:0072594)2.69148824
82pseudouridine synthesis (GO:0001522)2.66706854
83RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.65277771
84peptidyl-histidine modification (GO:0018202)2.63168284
85tRNA processing (GO:0008033)2.62395690
86regulation of regulatory T cell differentiation (GO:0045589)2.61786634
87kinetochore assembly (GO:0051382)2.60351665
88protein targeting to mitochondrion (GO:0006626)2.58312744
89regulation of cellular respiration (GO:0043457)2.57519606
90nucleoside triphosphate biosynthetic process (GO:0009142)2.54858415
91positive regulation of T cell apoptotic process (GO:0070234)2.52150041
92protein localization to mitochondrion (GO:0070585)2.51628817
93transcription-coupled nucleotide-excision repair (GO:0006283)2.49335415
94chromatin remodeling at centromere (GO:0031055)2.47636427
95nonmotile primary cilium assembly (GO:0035058)2.47529136
96CTP biosynthetic process (GO:0006241)2.46671758
97CTP metabolic process (GO:0046036)2.46671758
98DNA strand renaturation (GO:0000733)2.44951418
99parturition (GO:0007567)2.44906355
100pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.44071076

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human4.75954752
2EST1_17652178_ChIP-ChIP_JURKAT_Human4.55947293
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.50525328
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.41259521
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.47402993
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.37850123
7MYC_18555785_ChIP-Seq_MESCs_Mouse3.34386208
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.23533035
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.21611087
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.17839669
11ELK1_19687146_ChIP-ChIP_HELA_Human2.39612930
12FOXP3_21729870_ChIP-Seq_TREG_Human2.38491367
13TTF2_22483619_ChIP-Seq_HELA_Human2.35870935
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.26554648
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.26211165
16VDR_23849224_ChIP-Seq_CD4+_Human2.16370554
17FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.14792019
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.13154850
19MYC_18358816_ChIP-ChIP_MESCs_Mouse2.06775495
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.03206548
21VDR_22108803_ChIP-Seq_LS180_Human2.02768310
22ZNF274_21170338_ChIP-Seq_K562_Hela2.01494073
23YY1_21170310_ChIP-Seq_MESCs_Mouse1.97053481
24CREB1_15753290_ChIP-ChIP_HEK293T_Human1.95591460
25NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.92932573
26THAP11_20581084_ChIP-Seq_MESCs_Mouse1.91877627
27MYC_18940864_ChIP-ChIP_HL60_Human1.85200440
28E2F4_17652178_ChIP-ChIP_JURKAT_Human1.84912490
29HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.77743612
30SRF_21415370_ChIP-Seq_HL-1_Mouse1.76168071
31CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.75769757
32XRN2_22483619_ChIP-Seq_HELA_Human1.75549884
33ELF1_17652178_ChIP-ChIP_JURKAT_Human1.75176398
34IRF1_19129219_ChIP-ChIP_H3396_Human1.73314357
35EZH2_22144423_ChIP-Seq_EOC_Human1.72532059
36PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.71374646
37MYC_19030024_ChIP-ChIP_MESCs_Mouse1.68737075
38CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.65138447
39GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57619068
40EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.52691790
41NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.52666553
42GABP_19822575_ChIP-Seq_HepG2_Human1.49762766
43FLI1_27457419_Chip-Seq_LIVER_Mouse1.41265808
44EWS_26573619_Chip-Seq_HEK293_Human1.37427819
45TP53_22573176_ChIP-Seq_HFKS_Human1.30814769
46ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29267031
47ELK1_22589737_ChIP-Seq_MCF10A_Human1.27647252
48GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.27587255
49E2F1_18555785_ChIP-Seq_MESCs_Mouse1.27376600
50MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.25708153
51POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25347209
52RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.24975462
53CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.15520023
54PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13233054
55FOXA1_25329375_ChIP-Seq_VCAP_Human1.13049344
56FOXA1_27270436_Chip-Seq_PROSTATE_Human1.13049344
57BMI1_23680149_ChIP-Seq_NPCS_Mouse1.12993935
58EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.12912631
59KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11138929
60SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.10495941
61MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.09711497
62ETV2_25802403_ChIP-Seq_MESCs_Mouse1.08839302
63EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.07609599
64FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.04599240
65P53_21459846_ChIP-Seq_SAOS-2_Human1.03353375
66CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.01742190
67TAF2_19829295_ChIP-Seq_ESCs_Human1.01363315
68AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99815464
69NOTCH1_21737748_ChIP-Seq_TLL_Human0.99365261
70DCP1A_22483619_ChIP-Seq_HELA_Human0.98414912
71HOXB4_20404135_ChIP-ChIP_EML_Mouse0.96493316
72CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.96068074
73FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.95369584
74CBX2_27304074_Chip-Seq_ESCs_Mouse0.94950886
75GATA3_21878914_ChIP-Seq_MCF-7_Human0.94602281
76PCGF2_27294783_Chip-Seq_NPCs_Mouse0.93367180
77ERA_21632823_ChIP-Seq_H3396_Human0.91858481
78NCOR_22424771_ChIP-Seq_293T_Human0.90615915
79CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.90167311
80FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.90145380
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.89352999
82PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.89046666
83SOX2_16153702_ChIP-ChIP_HESCs_Human0.88558780
84RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.87479660
85NANOG_20526341_ChIP-Seq_ESCs_Human0.86151079
86YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.85705062
87PADI4_21655091_ChIP-ChIP_MCF-7_Human0.84539005
88MYC_19829295_ChIP-Seq_ESCs_Human0.82937897
89AR_20517297_ChIP-Seq_VCAP_Human0.82656135
90GATA3_21867929_ChIP-Seq_TH1_Mouse0.82433681
91PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.81915544
92EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.80226357
93FOXP1_21924763_ChIP-Seq_HESCs_Human0.79336931
94YY1_22570637_ChIP-Seq_MALME-3M_Human0.79003518
95SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.78365958
96HOXB7_26014856_ChIP-Seq_BT474_Human0.78203947
97SRY_22984422_ChIP-ChIP_TESTIS_Rat0.77987339
98FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76579063
99TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.75124968
100P300_19829295_ChIP-Seq_ESCs_Human0.74864377

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.14404018
2MP0006292_abnormal_olfactory_placode4.87794835
3MP0005360_urolithiasis3.89325002
4MP0003878_abnormal_ear_physiology3.52155947
5MP0005377_hearing/vestibular/ear_phenot3.52155947
6MP0003646_muscle_fatigue2.75510123
7MP0004142_abnormal_muscle_tone2.75085866
8MP0003136_yellow_coat_color2.66862903
9MP0008789_abnormal_olfactory_epithelium2.63374474
10MP0004742_abnormal_vestibular_system2.46725374
11MP0001293_anophthalmia2.31788971
12MP0002736_abnormal_nociception_after2.28122335
13MP0002653_abnormal_ependyma_morphology2.21489166
14MP0002102_abnormal_ear_morphology2.18212076
15MP0002837_dystrophic_cardiac_calcinosis2.10335848
16MP0010030_abnormal_orbit_morphology1.99591946
17MP0005499_abnormal_olfactory_system1.99033407
18MP0005394_taste/olfaction_phenotype1.99033407
19MP0004147_increased_porphyrin_level1.98337090
20MP0004885_abnormal_endolymph1.92341009
21MP0002277_abnormal_respiratory_mucosa1.90186383
22MP0001968_abnormal_touch/_nociception1.76857772
23MP0002938_white_spotting1.76364339
24MP0001485_abnormal_pinna_reflex1.64546760
25MP0002234_abnormal_pharynx_morphology1.61430651
26MP0003786_premature_aging1.58882040
27MP0004043_abnormal_pH_regulation1.51058717
28MP0008877_abnormal_DNA_methylation1.43881668
29MP0005084_abnormal_gallbladder_morpholo1.36246707
30MP0000049_abnormal_middle_ear1.36006699
31MP0005551_abnormal_eye_electrophysiolog1.29997409
32MP0005423_abnormal_somatic_nervous1.26038475
33MP0004145_abnormal_muscle_electrophysio1.24851630
34MP0000604_amyloidosis1.21220799
35MP0008872_abnormal_physiological_respon1.20865911
36MP0000631_abnormal_neuroendocrine_gland1.18389301
37MP0003122_maternal_imprinting1.18309255
38MP0003938_abnormal_ear_development1.17716372
39MP0001853_heart_inflammation1.16544605
40MP0002272_abnormal_nervous_system1.15886228
41MP0001348_abnormal_lacrimal_gland1.14525558
42MP0005646_abnormal_pituitary_gland1.12899440
43MP0006072_abnormal_retinal_apoptosis1.10295649
44MP0000026_abnormal_inner_ear1.08735844
45MP0005174_abnormal_tail_pigmentation1.05319148
46MP0004133_heterotaxia1.04225432
47MP0003186_abnormal_redox_activity1.00780244
48MP0000566_synostosis0.98772289
49MP0002735_abnormal_chemical_nociception0.98609901
50MP0009053_abnormal_anal_canal0.97936630
51MP0005253_abnormal_eye_physiology0.97135333
52MP0003011_delayed_dark_adaptation0.96822278
53MP0001905_abnormal_dopamine_level0.96701667
54MP0002095_abnormal_skin_pigmentation0.96084227
55MP0003123_paternal_imprinting0.91037262
56MP0009764_decreased_sensitivity_to0.90146552
57MP0009745_abnormal_behavioral_response0.89099943
58MP0004957_abnormal_blastocyst_morpholog0.88984964
59MP0003329_amyloid_beta_deposits0.88171661
60MP0003718_maternal_effect0.87592310
61MP0003567_abnormal_fetal_cardiomyocyte0.86324401
62MP0008995_early_reproductive_senescence0.85696350
63MP0001919_abnormal_reproductive_system0.84995557
64MP0005379_endocrine/exocrine_gland_phen0.84577629
65MP0001984_abnormal_olfaction0.83530869
66MP0002557_abnormal_social/conspecific_i0.82855183
67MP0000538_abnormal_urinary_bladder0.82175461
68MP0005332_abnormal_amino_acid0.81029060
69MP0003937_abnormal_limbs/digits/tail_de0.80336450
70MP0005391_vision/eye_phenotype0.80288436
71MP0000778_abnormal_nervous_system0.79237450
72MP0009046_muscle_twitch0.78785937
73MP0003121_genomic_imprinting0.78315092
74MP0002876_abnormal_thyroid_physiology0.77238248
75MP0003936_abnormal_reproductive_system0.75767927
76MP0005389_reproductive_system_phenotype0.75411896
77MP0008875_abnormal_xenobiotic_pharmacok0.74901570
78MP0002697_abnormal_eye_size0.74287028
79MP0003119_abnormal_digestive_system0.73257787
80MP0008058_abnormal_DNA_repair0.72959814
81MP0003195_calcinosis0.71829874
82MP0002148_abnormal_hypersensitivity_rea0.71715389
83MP0002638_abnormal_pupillary_reflex0.71614428
84MP0000372_irregular_coat_pigmentation0.71271215
85MP0002233_abnormal_nose_morphology0.70851225
86MP0002733_abnormal_thermal_nociception0.70640619
87MP0001970_abnormal_pain_threshold0.70529810
88MP0000537_abnormal_urethra_morphology0.70360361
89MP0002163_abnormal_gland_morphology0.68202645
90MP0001986_abnormal_taste_sensitivity0.67673886
91MP0001963_abnormal_hearing_physiology0.67186881
92MP0001440_abnormal_grooming_behavior0.67029530
93MP0003787_abnormal_imprinting0.66904884
94MP0001835_abnormal_antigen_presentation0.66573453
95MP0000685_abnormal_immune_system0.65010988
96MP0001501_abnormal_sleep_pattern0.64807564
97MP0001286_abnormal_eye_development0.64178012
98MP0000569_abnormal_digit_pigmentation0.63077140
99MP0002210_abnormal_sex_determination0.62695926
100MP0002249_abnormal_larynx_morphology0.62481818

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)6.10098275
2Increased hepatocellular lipid droplets (HP:0006565)4.84523771
3Acute necrotizing encephalopathy (HP:0006965)4.82174288
4Abnormality of cells of the erythroid lineage (HP:0012130)4.70296747
5Lipid accumulation in hepatocytes (HP:0006561)4.59649057
6Abnormal mitochondria in muscle tissue (HP:0008316)4.31669948
7Mitochondrial inheritance (HP:0001427)4.29816924
8Acute encephalopathy (HP:0006846)4.24278233
9Abnormal number of erythroid precursors (HP:0012131)4.18639071
10Macrocytic anemia (HP:0001972)3.87976068
11Progressive macrocephaly (HP:0004481)3.87924988
12Increased CSF lactate (HP:0002490)3.86238908
13Renal Fanconi syndrome (HP:0001994)3.83049297
14Abnormality of the pons (HP:0007361)3.75662259
15Septo-optic dysplasia (HP:0100842)3.72289145
16Congenital, generalized hypertrichosis (HP:0004540)3.67216211
17Hypoplasia of the pons (HP:0012110)3.44185158
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.43877753
19Increased intramyocellular lipid droplets (HP:0012240)3.13105811
20Colon cancer (HP:0003003)3.01566891
21Aplasia/Hypoplasia of the sacrum (HP:0008517)3.00968137
22Hepatocellular necrosis (HP:0001404)2.98876553
23Pallor (HP:0000980)2.95987852
24Pancreatic fibrosis (HP:0100732)2.92871352
25Rib fusion (HP:0000902)2.92324311
26Hepatic necrosis (HP:0002605)2.87716215
27Abnormal ciliary motility (HP:0012262)2.85027902
28Cerebral edema (HP:0002181)2.83016403
29Exertional dyspnea (HP:0002875)2.80073348
30Optic disc pallor (HP:0000543)2.76382969
31Renal cortical cysts (HP:0000803)2.72326018
32Increased muscle lipid content (HP:0009058)2.71368110
33Congenital stationary night blindness (HP:0007642)2.67876310
34Absent septum pellucidum (HP:0001331)2.65732188
35Respiratory difficulties (HP:0002880)2.53883796
36Aplasia/Hypoplasia of the spleen (HP:0010451)2.52910244
37Abnormality of renal resorption (HP:0011038)2.52094679
38Prostate neoplasm (HP:0100787)2.51382400
39Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.49335098
40Maternal diabetes (HP:0009800)2.47619171
41Sclerocornea (HP:0000647)2.44565864
42Pancytopenia (HP:0001876)2.43505231
43Abnormal respiratory motile cilium physiology (HP:0012261)2.42781391
44Increased serum lactate (HP:0002151)2.41757660
45Abnormality of the renal cortex (HP:0011035)2.41386107
46Lactic acidosis (HP:0003128)2.39230862
47Molar tooth sign on MRI (HP:0002419)2.37966591
48Abnormality of midbrain morphology (HP:0002418)2.37966591
49Pancreatic cysts (HP:0001737)2.35821534
50True hermaphroditism (HP:0010459)2.34950431
513-Methylglutaconic aciduria (HP:0003535)2.33586558
52Asplenia (HP:0001746)2.32847099
53Methylmalonic aciduria (HP:0012120)2.27804896
54IgG deficiency (HP:0004315)2.27259437
55Abnormality of urine glucose concentration (HP:0011016)2.18990228
56Glycosuria (HP:0003076)2.18990228
57Nephronophthisis (HP:0000090)2.17552804
58Leukodystrophy (HP:0002415)2.15112262
59Respiratory failure (HP:0002878)2.14246275
60Oral leukoplakia (HP:0002745)2.13246565
61Bilateral microphthalmos (HP:0007633)2.13074153
62Abnormal respiratory motile cilium morphology (HP:0005938)2.06587724
63Abnormal respiratory epithelium morphology (HP:0012253)2.06587724
64Exercise intolerance (HP:0003546)2.06391836
65Abnormality of the septum pellucidum (HP:0007375)2.04472681
66Medial flaring of the eyebrow (HP:0010747)2.01999917
67Anophthalmia (HP:0000528)1.99692622
68Abnormality of the renal medulla (HP:0100957)1.98687904
69Agitation (HP:0000713)1.97606674
70Hyperphosphaturia (HP:0003109)1.96126523
71Abnormality of DNA repair (HP:0003254)1.96063277
72Hyperglycinemia (HP:0002154)1.93118940
73Lethargy (HP:0001254)1.92258632
74Bile duct proliferation (HP:0001408)1.90967729
75Abnormal biliary tract physiology (HP:0012439)1.90967729
76Type II lissencephaly (HP:0007260)1.90364849
77Depressed nasal ridge (HP:0000457)1.89992687
78Myokymia (HP:0002411)1.87396838
79Absent rod-and cone-mediated responses on ERG (HP:0007688)1.85653123
80Abnormal drinking behavior (HP:0030082)1.83729101
81Polydipsia (HP:0001959)1.83729101
82Dynein arm defect of respiratory motile cilia (HP:0012255)1.82990649
83Absent/shortened dynein arms (HP:0200106)1.82990649
84Neutropenia (HP:0001875)1.82593027
85Methylmalonic acidemia (HP:0002912)1.81054845
86Partial duplication of thumb phalanx (HP:0009944)1.80937302
87Abnormality of the renal collecting system (HP:0004742)1.80242938
88Rhinitis (HP:0012384)1.79871047
89Anterior segment dysgenesis (HP:0007700)1.78179103
90Optic nerve hypoplasia (HP:0000609)1.77867186
91Generalized aminoaciduria (HP:0002909)1.77616921
92Duplicated collecting system (HP:0000081)1.77556572
93Renal dysplasia (HP:0000110)1.76675156
94Chorioretinal atrophy (HP:0000533)1.76287061
95Pendular nystagmus (HP:0012043)1.75925692
96Cutaneous melanoma (HP:0012056)1.75644966
97Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.73307630
98Aplastic anemia (HP:0001915)1.73220640
99Stomatitis (HP:0010280)1.67229369
100Cleft eyelid (HP:0000625)1.67152492

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.83033614
2TAF14.49722562
3WNK44.18535578
4TXK3.46104138
5ZAK3.20075766
6NUAK13.17078021
7BMPR1B2.57783134
8CDC72.54696468
9NME12.47645742
10SMG12.32046038
11VRK12.26049462
12TLK12.04823594
13ADRBK21.96853712
14DYRK21.92570495
15ACVR1B1.88136912
16BUB11.70601185
17GRK11.69910417
18STK391.68668808
19TIE11.68443713
20CDK191.60994486
21PIK3CA1.60758350
22TGFBR11.53870712
23EPHB21.48577732
24STK161.39341311
25FRK1.37235654
26CDK81.31449131
27PASK1.27291045
28OXSR11.25368993
29MAP2K21.20449157
30PLK41.11685762
31WNK11.10014858
32TNIK1.06302190
33WNK31.06149803
34PINK11.05341520
35MAP4K11.04062708
36GRK70.97693442
37PLK30.97244923
38MAP4K20.95332477
39MUSK0.86693627
40TEC0.83076596
41CAMK10.82915769
42IKBKB0.79074783
43LRRK20.75547089
44EIF2AK20.74917424
45DAPK30.74488709
46CSNK1G20.70644490
47CSNK1G30.69944524
48GRK50.69725734
49ADRBK10.68740502
50IKBKE0.67626258
51PLK20.67550592
52NME20.65783930
53CSNK1A1L0.65669694
54PLK10.61326719
55CSNK2A20.60517307
56CHEK20.58114348
57PIK3CG0.55320835
58PAK30.55151952
59ABL20.54143169
60MAP3K110.54091701
61ITK0.54064708
62MAPKAPK50.54002888
63INSRR0.52889326
64SRPK10.52763711
65CAMK1G0.48542097
66TAOK30.47897222
67CSNK1G10.46344149
68CAMK1D0.45782504
69AURKB0.44504805
70AURKA0.44256869
71MAP3K140.43685002
72RIPK40.42821440
73CSNK2A10.41740534
74PRKCQ0.40252283
75PHKG20.38291248
76PHKG10.38291248
77CSNK1E0.38244083
78PRKACA0.37670404
79ATR0.37419292
80MAP2K60.36158999
81FGFR10.35360043
82OBSCN0.34792636
83ERBB20.33773737
84SYK0.33502247
85PRKCG0.32007642
86CDK70.31120491
87DYRK1A0.28558819
88PNCK0.26804180
89EIF2AK10.24444698
90NEK10.24277543
91PRKCZ0.22321349
92RPS6KA60.21860916
93CSNK1D0.21328683
94CHUK0.20884444
95MARK30.20618887
96MAP2K70.19771392
97STK110.19730494
98CDK90.18532174
99PRKCA0.18201189
100MST40.17639938

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.46912243
2Oxidative phosphorylation_Homo sapiens_hsa001904.63102592
3Parkinsons disease_Homo sapiens_hsa050123.89944084
4RNA polymerase_Homo sapiens_hsa030203.31471292
5Proteasome_Homo sapiens_hsa030503.13246747
6Huntingtons disease_Homo sapiens_hsa050162.94703110
7Alzheimers disease_Homo sapiens_hsa050102.68787587
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.50663707
9Cardiac muscle contraction_Homo sapiens_hsa042602.36859151
10Protein export_Homo sapiens_hsa030602.35275085
11Mismatch repair_Homo sapiens_hsa034302.03277567
12Homologous recombination_Homo sapiens_hsa034401.96914222
13Nucleotide excision repair_Homo sapiens_hsa034201.90017709
14RNA degradation_Homo sapiens_hsa030181.85005856
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.83983346
16Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.80930481
17Pyrimidine metabolism_Homo sapiens_hsa002401.75986487
18Basal transcription factors_Homo sapiens_hsa030221.61283173
19Sulfur relay system_Homo sapiens_hsa041221.53754798
20Linoleic acid metabolism_Homo sapiens_hsa005911.50519185
21Asthma_Homo sapiens_hsa053101.46242365
22DNA replication_Homo sapiens_hsa030301.37718363
23Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.32790921
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.31657216
25Caffeine metabolism_Homo sapiens_hsa002321.31176848
26Tryptophan metabolism_Homo sapiens_hsa003801.30588365
27Base excision repair_Homo sapiens_hsa034101.27499397
28One carbon pool by folate_Homo sapiens_hsa006701.22017005
29Spliceosome_Homo sapiens_hsa030401.20829375
30Purine metabolism_Homo sapiens_hsa002301.20382844
31Intestinal immune network for IgA production_Homo sapiens_hsa046721.11812618
32alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.10157326
33Sulfur metabolism_Homo sapiens_hsa009201.01405298
34Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.93645496
35Folate biosynthesis_Homo sapiens_hsa007900.91860439
36Basal cell carcinoma_Homo sapiens_hsa052170.90908395
37beta-Alanine metabolism_Homo sapiens_hsa004100.87934721
38Allograft rejection_Homo sapiens_hsa053300.86143968
39RNA transport_Homo sapiens_hsa030130.84272259
40Autoimmune thyroid disease_Homo sapiens_hsa053200.83986658
41Propanoate metabolism_Homo sapiens_hsa006400.80985283
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.79711190
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.78838681
44Arachidonic acid metabolism_Homo sapiens_hsa005900.78721416
45Phototransduction_Homo sapiens_hsa047440.78090667
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.77642986
47Fanconi anemia pathway_Homo sapiens_hsa034600.76506958
48Type I diabetes mellitus_Homo sapiens_hsa049400.74870408
49Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.73133000
50Chemical carcinogenesis_Homo sapiens_hsa052040.72938085
51Primary immunodeficiency_Homo sapiens_hsa053400.72932113
52Metabolic pathways_Homo sapiens_hsa011000.69756169
53Butanoate metabolism_Homo sapiens_hsa006500.69743922
54Glutathione metabolism_Homo sapiens_hsa004800.69046548
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.68753970
56Peroxisome_Homo sapiens_hsa041460.67577038
57Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64102518
58Graft-versus-host disease_Homo sapiens_hsa053320.63256637
59Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.63050790
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.61167574
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.58016379
62Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.57292098
63Nicotine addiction_Homo sapiens_hsa050330.53988301
64Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.52834151
65Vitamin digestion and absorption_Homo sapiens_hsa049770.51495990
66Fat digestion and absorption_Homo sapiens_hsa049750.51059705
67Collecting duct acid secretion_Homo sapiens_hsa049660.50544748
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.48839821
69Retinol metabolism_Homo sapiens_hsa008300.46549691
70Selenocompound metabolism_Homo sapiens_hsa004500.44814579
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.44429725
72Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.43896281
73Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.42148520
74Rheumatoid arthritis_Homo sapiens_hsa053230.41551499
75Morphine addiction_Homo sapiens_hsa050320.40937044
76Insulin secretion_Homo sapiens_hsa049110.40893598
77Ether lipid metabolism_Homo sapiens_hsa005650.39227412
78Mineral absorption_Homo sapiens_hsa049780.39169381
79Nitrogen metabolism_Homo sapiens_hsa009100.36387249
80Hedgehog signaling pathway_Homo sapiens_hsa043400.36197622
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.34523413
82Ovarian steroidogenesis_Homo sapiens_hsa049130.33411772
83Olfactory transduction_Homo sapiens_hsa047400.32921683
84Cyanoamino acid metabolism_Homo sapiens_hsa004600.32277724
85Pyruvate metabolism_Homo sapiens_hsa006200.31503574
86Non-homologous end-joining_Homo sapiens_hsa034500.31403872
87Hematopoietic cell lineage_Homo sapiens_hsa046400.31208101
88Tyrosine metabolism_Homo sapiens_hsa003500.30716719
89Fatty acid degradation_Homo sapiens_hsa000710.28998884
90Phenylalanine metabolism_Homo sapiens_hsa003600.28392616
91Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.27733986
92Fatty acid elongation_Homo sapiens_hsa000620.27708419
93Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26339849
94p53 signaling pathway_Homo sapiens_hsa041150.24461743
95Taste transduction_Homo sapiens_hsa047420.24209566
96Wnt signaling pathway_Homo sapiens_hsa043100.23460235
97Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.20735658
98Epstein-Barr virus infection_Homo sapiens_hsa051690.19418265
99Arginine and proline metabolism_Homo sapiens_hsa003300.18824971
100Primary bile acid biosynthesis_Homo sapiens_hsa001200.15741991

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »