

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.88991184 |
| 2 | ubiquinone metabolic process (GO:0006743) | 5.81289082 |
| 3 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 5.70507056 |
| 4 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 5.68846676 |
| 5 | neuronal action potential propagation (GO:0019227) | 5.34147564 |
| 6 | protein maturation by protein folding (GO:0022417) | 5.25117488 |
| 7 | ubiquinone biosynthetic process (GO:0006744) | 5.11481316 |
| 8 | response to redox state (GO:0051775) | 5.06847970 |
| 9 | estrogen biosynthetic process (GO:0006703) | 5.01313263 |
| 10 | dopamine transport (GO:0015872) | 4.82587333 |
| 11 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 4.65057194 |
| 12 | behavioral response to nicotine (GO:0035095) | 4.48364438 |
| 13 | astrocyte differentiation (GO:0048708) | 4.42192517 |
| 14 | cellular response to electrical stimulus (GO:0071257) | 4.41146976 |
| 15 | negative regulation of heart rate (GO:0010459) | 4.35497429 |
| 16 | behavioral response to ethanol (GO:0048149) | 4.34362565 |
| 17 | positive regulation of synaptic transmission, dopaminergic (GO:0032226) | 4.25211298 |
| 18 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 4.23891377 |
| 19 | quinone biosynthetic process (GO:1901663) | 4.15448584 |
| 20 | DNA damage induced protein phosphorylation (GO:0006975) | 4.14761596 |
| 21 | regulation of glucocorticoid secretion (GO:2000849) | 4.05675591 |
| 22 | negative regulation of phosphoprotein phosphatase activity (GO:0032515) | 3.95884073 |
| 23 | protein-chromophore linkage (GO:0018298) | 3.87415752 |
| 24 | photoreceptor cell differentiation (GO:0046530) | 3.85546853 |
| 25 | eye photoreceptor cell differentiation (GO:0001754) | 3.85546853 |
| 26 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.83128458 |
| 27 | nonmotile primary cilium assembly (GO:0035058) | 3.81835760 |
| 28 | dermatan sulfate biosynthetic process (GO:0030208) | 3.80506563 |
| 29 | early endosome to late endosome transport (GO:0045022) | 3.76716413 |
| 30 | membrane depolarization during action potential (GO:0086010) | 3.76638913 |
| 31 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.71640986 |
| 32 | dorsal/ventral axis specification (GO:0009950) | 3.71598454 |
| 33 | positive regulation of dendritic spine development (GO:0060999) | 3.70303307 |
| 34 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 3.69404534 |
| 35 | inactivation of MAPK activity (GO:0000188) | 3.64638739 |
| 36 | postsynaptic membrane organization (GO:0001941) | 3.62806200 |
| 37 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.55002692 |
| 38 | photoperiodism (GO:0009648) | 3.53839205 |
| 39 | negative regulation of circadian rhythm (GO:0042754) | 3.53636603 |
| 40 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 3.48167723 |
| 41 | regulation of neuron projection regeneration (GO:0070570) | 3.47922853 |
| 42 | regulation of axon regeneration (GO:0048679) | 3.47922853 |
| 43 | insulin secretion (GO:0030073) | 3.46420860 |
| 44 | aldehyde catabolic process (GO:0046185) | 3.45414371 |
| 45 | negative regulation of cation channel activity (GO:2001258) | 3.44577267 |
| 46 | pattern specification involved in kidney development (GO:0061004) | 3.43873003 |
| 47 | positive regulation of vesicle fusion (GO:0031340) | 3.43175792 |
| 48 | protein export from nucleus (GO:0006611) | 3.41889799 |
| 49 | toxin metabolic process (GO:0009404) | 3.41471588 |
| 50 | dermatan sulfate metabolic process (GO:0030205) | 3.40671196 |
| 51 | regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) | 3.40603966 |
| 52 | negative regulation of calcium ion transmembrane transport (GO:1903170) | 3.32079767 |
| 53 | negative regulation of calcium ion transmembrane transporter activity (GO:1901020) | 3.32079767 |
| 54 | regulation of actin nucleation (GO:0051125) | 3.30702779 |
| 55 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 3.24548088 |
| 56 | positive regulation of action potential (GO:0045760) | 3.21756056 |
| 57 | regulation of corticosteroid hormone secretion (GO:2000846) | 3.18862837 |
| 58 | negative regulation of sequestering of calcium ion (GO:0051283) | 3.16912342 |
| 59 | release of sequestered calcium ion into cytosol (GO:0051209) | 3.16912342 |
| 60 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.15841390 |
| 61 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.15841390 |
| 62 | fucose catabolic process (GO:0019317) | 3.14098639 |
| 63 | L-fucose metabolic process (GO:0042354) | 3.14098639 |
| 64 | L-fucose catabolic process (GO:0042355) | 3.14098639 |
| 65 | serotonin metabolic process (GO:0042428) | 3.12833498 |
| 66 | piRNA metabolic process (GO:0034587) | 3.12147800 |
| 67 | negative regulation of neurotransmitter transport (GO:0051589) | 3.08449551 |
| 68 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.07486898 |
| 69 | collecting duct development (GO:0072044) | 3.06377090 |
| 70 | catecholamine transport (GO:0051937) | 3.05318401 |
| 71 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.03322008 |
| 72 | synaptic vesicle maturation (GO:0016188) | 2.99073359 |
| 73 | regulation of sequestering of calcium ion (GO:0051282) | 2.98630157 |
| 74 | regulation of calcium ion-dependent exocytosis (GO:0017158) | 2.98235582 |
| 75 | smooth muscle contraction (GO:0006939) | 2.96879381 |
| 76 | glycerophospholipid catabolic process (GO:0046475) | 2.93313609 |
| 77 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 2.91373807 |
| 78 | response to vitamin E (GO:0033197) | 2.88304080 |
| 79 | entrainment of circadian clock by photoperiod (GO:0043153) | 2.88195371 |
| 80 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.85783506 |
| 81 | primary amino compound metabolic process (GO:1901160) | 2.82085197 |
| 82 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 2.81026466 |
| 83 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 2.81026466 |
| 84 | regulation of translation, ncRNA-mediated (GO:0045974) | 2.81026466 |
| 85 | regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 2.80276067 |
| 86 | regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO | 2.80142993 |
| 87 | renal tubule development (GO:0061326) | 2.78989785 |
| 88 | triglyceride homeostasis (GO:0070328) | 2.78792365 |
| 89 | acylglycerol homeostasis (GO:0055090) | 2.78792365 |
| 90 | nucleobase catabolic process (GO:0046113) | 2.78663670 |
| 91 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 2.74411281 |
| 92 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 2.74411281 |
| 93 | positive regulation of vascular permeability (GO:0043117) | 2.73774886 |
| 94 | positive regulation of sodium ion transport (GO:0010765) | 2.71847974 |
| 95 | axoneme assembly (GO:0035082) | 2.70638397 |
| 96 | axonal fasciculation (GO:0007413) | 2.69759286 |
| 97 | regulation of acrosome reaction (GO:0060046) | 2.68417862 |
| 98 | olfactory bulb development (GO:0021772) | 2.66559144 |
| 99 | labyrinthine layer development (GO:0060711) | 2.65035384 |
| 100 | vitamin biosynthetic process (GO:0009110) | 2.63262382 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 4.16084509 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.14995905 |
| 3 | TAF15_26573619_Chip-Seq_HEK293_Human | 3.51182717 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.69916342 |
| 5 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.57797627 |
| 6 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.42959859 |
| 7 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.16788585 |
| 8 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.13516609 |
| 9 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.01124243 |
| 10 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.00035523 |
| 11 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.95610947 |
| 12 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.91640363 |
| 13 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.91080277 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.84854579 |
| 15 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.81928866 |
| 16 | FUS_26573619_Chip-Seq_HEK293_Human | 1.81204698 |
| 17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.72555012 |
| 18 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.71255556 |
| 19 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.70496411 |
| 20 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.70293180 |
| 21 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.64697338 |
| 22 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.63718734 |
| 23 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.60605476 |
| 24 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.58858786 |
| 25 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.49893294 |
| 26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.49274943 |
| 27 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.47579734 |
| 28 | AR_25329375_ChIP-Seq_VCAP_Human | 1.47096546 |
| 29 | TP53_16413492_ChIP-PET_HCT116_Human | 1.47001687 |
| 30 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.46996999 |
| 31 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.46720594 |
| 32 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.46476049 |
| 33 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.46476049 |
| 34 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.41800018 |
| 35 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.40081889 |
| 36 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.39579203 |
| 37 | STAT3_23295773_ChIP-Seq_U87_Human | 1.39208478 |
| 38 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.38856227 |
| 39 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.38690233 |
| 40 | TCF4_23295773_ChIP-Seq_U87_Human | 1.38221489 |
| 41 | TBL1_22424771_ChIP-Seq_293T_Human | 1.37837743 |
| 42 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.30428971 |
| 43 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.29095762 |
| 44 | NFYA_21822215_ChIP-Seq_K562_Human | 1.28357932 |
| 45 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.28149919 |
| 46 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.27326624 |
| 47 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.25959387 |
| 48 | NFYB_21822215_ChIP-Seq_K562_Human | 1.23626475 |
| 49 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.21726058 |
| 50 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.21446469 |
| 51 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.20195445 |
| 52 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.19666357 |
| 53 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.18335157 |
| 54 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18265277 |
| 55 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.18218023 |
| 56 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.17733755 |
| 57 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.15380934 |
| 58 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.15357009 |
| 59 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.15026468 |
| 60 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.14814684 |
| 61 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.14686516 |
| 62 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.14128009 |
| 63 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.13988027 |
| 64 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.13822753 |
| 65 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12909293 |
| 66 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.12375407 |
| 67 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.12340350 |
| 68 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.11493445 |
| 69 | P300_19829295_ChIP-Seq_ESCs_Human | 1.11129474 |
| 70 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.09979795 |
| 71 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.09839282 |
| 72 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.09666163 |
| 73 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.09399457 |
| 74 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.08219900 |
| 75 | GATA1_22025678_ChIP-Seq_K562_Human | 1.07934149 |
| 76 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.07765890 |
| 77 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.06369749 |
| 78 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.06085362 |
| 79 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.05512752 |
| 80 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.05436253 |
| 81 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.04848938 |
| 82 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.04840368 |
| 83 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.03821113 |
| 84 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.03608330 |
| 85 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.03374022 |
| 86 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.03308997 |
| 87 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03282151 |
| 88 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02978095 |
| 89 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.02842608 |
| 90 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.01952811 |
| 91 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.01683412 |
| 92 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.01250737 |
| 93 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.01114017 |
| 94 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.01043620 |
| 95 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.00358574 |
| 96 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.00153287 |
| 97 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.00086172 |
| 98 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.99961049 |
| 99 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.99717434 |
| 100 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.99600028 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002638_abnormal_pupillary_reflex | 5.94166790 |
| 2 | MP0001502_abnormal_circadian_rhythm | 3.40094714 |
| 3 | MP0003122_maternal_imprinting | 3.26794901 |
| 4 | MP0006276_abnormal_autonomic_nervous | 3.26163294 |
| 5 | MP0003121_genomic_imprinting | 3.25612133 |
| 6 | MP0003787_abnormal_imprinting | 3.13980953 |
| 7 | MP0009046_muscle_twitch | 3.06409305 |
| 8 | MP0002736_abnormal_nociception_after | 3.05995317 |
| 9 | MP0001968_abnormal_touch/_nociception | 2.62562569 |
| 10 | MP0001440_abnormal_grooming_behavior | 2.57299044 |
| 11 | MP0004859_abnormal_synaptic_plasticity | 2.55439707 |
| 12 | MP0002735_abnormal_chemical_nociception | 2.46809109 |
| 13 | MP0009780_abnormal_chondrocyte_physiolo | 2.45710600 |
| 14 | MP0005499_abnormal_olfactory_system | 2.23648716 |
| 15 | MP0005394_taste/olfaction_phenotype | 2.23648716 |
| 16 | MP0001984_abnormal_olfaction | 2.21302346 |
| 17 | MP0002909_abnormal_adrenal_gland | 2.18349435 |
| 18 | MP0008877_abnormal_DNA_methylation | 2.11139572 |
| 19 | MP0002572_abnormal_emotion/affect_behav | 2.00358357 |
| 20 | MP0003123_paternal_imprinting | 1.81544751 |
| 21 | MP0000569_abnormal_digit_pigmentation | 1.79487778 |
| 22 | MP0001501_abnormal_sleep_pattern | 1.77598935 |
| 23 | MP0009745_abnormal_behavioral_response | 1.76861481 |
| 24 | MP0002693_abnormal_pancreas_physiology | 1.74639977 |
| 25 | MP0003635_abnormal_synaptic_transmissio | 1.69364776 |
| 26 | MP0008789_abnormal_olfactory_epithelium | 1.68228493 |
| 27 | MP0002733_abnormal_thermal_nociception | 1.63864889 |
| 28 | MP0000778_abnormal_nervous_system | 1.63477197 |
| 29 | MP0000566_synostosis | 1.61318639 |
| 30 | MP0003879_abnormal_hair_cell | 1.60336533 |
| 31 | MP0001905_abnormal_dopamine_level | 1.59794946 |
| 32 | MP0005423_abnormal_somatic_nervous | 1.59189493 |
| 33 | MP0002557_abnormal_social/conspecific_i | 1.56903613 |
| 34 | MP0002272_abnormal_nervous_system | 1.55152318 |
| 35 | MP0003195_calcinosis | 1.53312055 |
| 36 | MP0002063_abnormal_learning/memory/cond | 1.51631518 |
| 37 | MP0005248_abnormal_Harderian_gland | 1.50730383 |
| 38 | MP0001970_abnormal_pain_threshold | 1.47010062 |
| 39 | MP0006072_abnormal_retinal_apoptosis | 1.46658255 |
| 40 | MP0002163_abnormal_gland_morphology | 1.40820637 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.36384423 |
| 42 | MP0005386_behavior/neurological_phenoty | 1.36295934 |
| 43 | MP0004924_abnormal_behavior | 1.36295934 |
| 44 | MP0002064_seizures | 1.35684807 |
| 45 | MP0005645_abnormal_hypothalamus_physiol | 1.31603290 |
| 46 | MP0000579_abnormal_nail_morphology | 1.30251192 |
| 47 | MP0000427_abnormal_hair_cycle | 1.28415886 |
| 48 | MP0005253_abnormal_eye_physiology | 1.26422060 |
| 49 | MP0004085_abnormal_heartbeat | 1.25038071 |
| 50 | MP0001485_abnormal_pinna_reflex | 1.23859701 |
| 51 | MP0002734_abnormal_mechanical_nocicepti | 1.21849326 |
| 52 | MP0005408_hypopigmentation | 1.17819770 |
| 53 | MP0003137_abnormal_impulse_conducting | 1.16392500 |
| 54 | MP0003646_muscle_fatigue | 1.16177315 |
| 55 | MP0003183_abnormal_peptide_metabolism | 1.15498340 |
| 56 | MP0002184_abnormal_innervation | 1.15436347 |
| 57 | MP0000230_abnormal_systemic_arterial | 1.14704118 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.13674760 |
| 59 | MP0003633_abnormal_nervous_system | 1.10002307 |
| 60 | MP0001346_abnormal_lacrimal_gland | 1.09848998 |
| 61 | MP0006292_abnormal_olfactory_placode | 1.09842133 |
| 62 | MP0001486_abnormal_startle_reflex | 1.05206961 |
| 63 | MP0003950_abnormal_plasma_membrane | 1.00008699 |
| 64 | MP0003890_abnormal_embryonic-extraembry | 0.98160934 |
| 65 | MP0003631_nervous_system_phenotype | 0.97404006 |
| 66 | MP0008995_early_reproductive_senescence | 0.96303670 |
| 67 | MP0005535_abnormal_body_temperature | 0.93741674 |
| 68 | MP0005595_abnormal_vascular_smooth | 0.93042204 |
| 69 | MP0001348_abnormal_lacrimal_gland | 0.90310627 |
| 70 | MP0002938_white_spotting | 0.89300284 |
| 71 | MP0002168_other_aberrant_phenotype | 0.88047506 |
| 72 | MP0010386_abnormal_urinary_bladder | 0.88020938 |
| 73 | MP0004133_heterotaxia | 0.87665123 |
| 74 | MP0005195_abnormal_posterior_eye | 0.86412888 |
| 75 | MP0001919_abnormal_reproductive_system | 0.84327443 |
| 76 | MP0002229_neurodegeneration | 0.83813931 |
| 77 | MP0004811_abnormal_neuron_physiology | 0.83780598 |
| 78 | MP0009703_decreased_birth_body | 0.80053619 |
| 79 | MP0008875_abnormal_xenobiotic_pharmacok | 0.79854828 |
| 80 | MP0005379_endocrine/exocrine_gland_phen | 0.78153992 |
| 81 | MP0002067_abnormal_sensory_capabilities | 0.76314142 |
| 82 | MP0000631_abnormal_neuroendocrine_gland | 0.76190865 |
| 83 | MP0002882_abnormal_neuron_morphology | 0.75942234 |
| 84 | MP0000383_abnormal_hair_follicle | 0.75636700 |
| 85 | MP0002971_abnormal_brown_adipose | 0.74804569 |
| 86 | MP0004145_abnormal_muscle_electrophysio | 0.74056915 |
| 87 | MP0004885_abnormal_endolymph | 0.71896655 |
| 88 | MP0002078_abnormal_glucose_homeostasis | 0.71891060 |
| 89 | MP0005365_abnormal_bile_salt | 0.71358436 |
| 90 | MP0005389_reproductive_system_phenotype | 0.68950790 |
| 91 | MP0010329_abnormal_lipoprotein_level | 0.68422727 |
| 92 | MP0001324_abnormal_eye_pigmentation | 0.67920314 |
| 93 | MP0004147_increased_porphyrin_level | 0.67244272 |
| 94 | MP0000372_irregular_coat_pigmentation | 0.67106541 |
| 95 | MP0003632_abnormal_nervous_system | 0.66094126 |
| 96 | MP0003953_abnormal_hormone_level | 0.65931077 |
| 97 | MP0004233_abnormal_muscle_weight | 0.64502459 |
| 98 | MP0004742_abnormal_vestibular_system | 0.63625863 |
| 99 | MP0001986_abnormal_taste_sensitivity | 0.62423713 |
| 100 | MP0002066_abnormal_motor_capabilities/c | 0.62370279 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Limb dystonia (HP:0002451) | 6.45340104 |
| 2 | Diastasis recti (HP:0001540) | 5.82560704 |
| 3 | Hyperventilation (HP:0002883) | 5.66296215 |
| 4 | Distal arthrogryposis (HP:0005684) | 4.86587172 |
| 5 | Mesangial abnormality (HP:0001966) | 4.82026049 |
| 6 | Abnormal rod and cone electroretinograms (HP:0008323) | 4.19753554 |
| 7 | Difficulty running (HP:0009046) | 4.17756539 |
| 8 | Hip dysplasia (HP:0001385) | 3.65572017 |
| 9 | Rib fusion (HP:0000902) | 3.56464721 |
| 10 | Microretrognathia (HP:0000308) | 3.29022989 |
| 11 | Abnormality of the labia minora (HP:0012880) | 3.21889886 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 3.19466919 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.19466919 |
| 14 | Abnormal pupillary function (HP:0007686) | 3.17434327 |
| 15 | Pancreatic fibrosis (HP:0100732) | 3.13508654 |
| 16 | Cerebral hypomyelination (HP:0006808) | 3.03555556 |
| 17 | Exotropia (HP:0000577) | 3.02621688 |
| 18 | Protruding ear (HP:0000411) | 3.02578965 |
| 19 | Limb hypertonia (HP:0002509) | 3.01312851 |
| 20 | Hypothermia (HP:0002045) | 2.94084304 |
| 21 | Polyphagia (HP:0002591) | 2.93308333 |
| 22 | Left ventricular hypertrophy (HP:0001712) | 2.92634798 |
| 23 | Gait imbalance (HP:0002141) | 2.89181648 |
| 24 | Abnormal biliary tract physiology (HP:0012439) | 2.87453040 |
| 25 | Bile duct proliferation (HP:0001408) | 2.87453040 |
| 26 | Lissencephaly (HP:0001339) | 2.81491208 |
| 27 | Poor coordination (HP:0002370) | 2.80149292 |
| 28 | Nephronophthisis (HP:0000090) | 2.79801037 |
| 29 | Partial agenesis of the corpus callosum (HP:0001338) | 2.78303675 |
| 30 | Nephrogenic diabetes insipidus (HP:0009806) | 2.74051988 |
| 31 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.72624250 |
| 32 | Medial flaring of the eyebrow (HP:0010747) | 2.69020944 |
| 33 | Vertebral arch anomaly (HP:0008438) | 2.66928699 |
| 34 | Chronic hepatic failure (HP:0100626) | 2.65811854 |
| 35 | Natal tooth (HP:0000695) | 2.65257421 |
| 36 | Congenital primary aphakia (HP:0007707) | 2.63164269 |
| 37 | Volvulus (HP:0002580) | 2.63072000 |
| 38 | Protruding tongue (HP:0010808) | 2.62467685 |
| 39 | Nasal speech (HP:0001611) | 2.52995017 |
| 40 | Long foot (HP:0001833) | 2.52369721 |
| 41 | Macroorchidism (HP:0000053) | 2.52192454 |
| 42 | Thin upper lip vermilion (HP:0000219) | 2.48913324 |
| 43 | Narrow forehead (HP:0000341) | 2.46119215 |
| 44 | Thoracic kyphosis (HP:0002942) | 2.40959092 |
| 45 | Overlapping toe (HP:0001845) | 2.40217386 |
| 46 | Infantile muscular hypotonia (HP:0008947) | 2.38097910 |
| 47 | Tracheomalacia (HP:0002779) | 2.35844297 |
| 48 | Large eyes (HP:0001090) | 2.32444388 |
| 49 | Sleep apnea (HP:0010535) | 2.31048872 |
| 50 | Genital tract atresia (HP:0001827) | 2.31030460 |
| 51 | Decreased circulating renin level (HP:0003351) | 2.27850619 |
| 52 | Abnormality of the aortic arch (HP:0012303) | 2.26805411 |
| 53 | EEG with generalized epileptiform discharges (HP:0011198) | 2.26536300 |
| 54 | Hypsarrhythmia (HP:0002521) | 2.25217748 |
| 55 | Abnormality of the renal medulla (HP:0100957) | 2.23253973 |
| 56 | Pachygyria (HP:0001302) | 2.20439245 |
| 57 | Agitation (HP:0000713) | 2.18224099 |
| 58 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.17442560 |
| 59 | Epileptiform EEG discharges (HP:0011182) | 2.17280753 |
| 60 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.17270822 |
| 61 | Abolished electroretinogram (ERG) (HP:0000550) | 2.14205953 |
| 62 | Metabolic alkalosis (HP:0200114) | 2.13813767 |
| 63 | Fetal akinesia sequence (HP:0001989) | 2.13461786 |
| 64 | True hermaphroditism (HP:0010459) | 2.10698971 |
| 65 | Highly arched eyebrow (HP:0002553) | 2.04317659 |
| 66 | Nephrotic syndrome (HP:0000100) | 2.02989812 |
| 67 | Personality changes (HP:0000751) | 2.01511643 |
| 68 | Vaginal atresia (HP:0000148) | 1.99157177 |
| 69 | Prominent nasal bridge (HP:0000426) | 1.99030542 |
| 70 | Unsteady gait (HP:0002317) | 1.97021488 |
| 71 | Abnormal drinking behavior (HP:0030082) | 1.94159235 |
| 72 | Polydipsia (HP:0001959) | 1.94159235 |
| 73 | Abnormal number of incisors (HP:0011064) | 1.94122650 |
| 74 | Pancreatic cysts (HP:0001737) | 1.93867401 |
| 75 | Esotropia (HP:0000565) | 1.93757743 |
| 76 | Primary atrial arrhythmia (HP:0001692) | 1.92045136 |
| 77 | Upper limb muscle weakness (HP:0003484) | 1.89300063 |
| 78 | Oligodontia (HP:0000677) | 1.88093984 |
| 79 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.88041843 |
| 80 | Decreased testicular size (HP:0008734) | 1.87688606 |
| 81 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.86760171 |
| 82 | Hypoplastic nipples (HP:0002557) | 1.86393291 |
| 83 | Asymmetry of the thorax (HP:0001555) | 1.85589830 |
| 84 | Type II lissencephaly (HP:0007260) | 1.81824815 |
| 85 | Epileptic encephalopathy (HP:0200134) | 1.81259832 |
| 86 | Cone-rod dystrophy (HP:0000548) | 1.80600314 |
| 87 | Abnormality of the musculature of the hand (HP:0001421) | 1.79507095 |
| 88 | Fragile skin (HP:0001030) | 1.78502899 |
| 89 | Tubular atrophy (HP:0000092) | 1.77370190 |
| 90 | Specific learning disability (HP:0001328) | 1.77129269 |
| 91 | Supraventricular tachycardia (HP:0004755) | 1.75856041 |
| 92 | Vitreoretinal degeneration (HP:0000655) | 1.73844661 |
| 93 | Cystic liver disease (HP:0006706) | 1.73391637 |
| 94 | Bifid tongue (HP:0010297) | 1.72417602 |
| 95 | Abnormality of the renal cortex (HP:0011035) | 1.71146917 |
| 96 | Postaxial hand polydactyly (HP:0001162) | 1.70893846 |
| 97 | Dyschromatopsia (HP:0007641) | 1.70000628 |
| 98 | Papilledema (HP:0001085) | 1.69869221 |
| 99 | Aplasia/Hypoplasia of the lens (HP:0008063) | 1.69847563 |
| 100 | Atrial fibrillation (HP:0005110) | 1.69649092 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K9 | 5.75436457 |
| 2 | WNK3 | 4.08366910 |
| 3 | PIK3CG | 3.52248928 |
| 4 | IRAK4 | 3.24375769 |
| 5 | CASK | 2.51040997 |
| 6 | SGK2 | 2.44217913 |
| 7 | PINK1 | 2.41619263 |
| 8 | PDK2 | 2.41234755 |
| 9 | CSNK1G3 | 2.39482957 |
| 10 | ACVR1B | 2.34955688 |
| 11 | CSNK1G1 | 2.28535369 |
| 12 | FRK | 2.22213495 |
| 13 | SGK3 | 2.03800249 |
| 14 | CAMK1D | 2.03461101 |
| 15 | CDK12 | 2.00343086 |
| 16 | CSNK1G2 | 1.88413253 |
| 17 | SGK223 | 1.86788571 |
| 18 | SGK494 | 1.86788571 |
| 19 | CAMK1G | 1.82813679 |
| 20 | PRKCH | 1.79724799 |
| 21 | MAP3K4 | 1.76676925 |
| 22 | PAK3 | 1.76421655 |
| 23 | MAPK13 | 1.74087725 |
| 24 | FGFR2 | 1.71248615 |
| 25 | MKNK2 | 1.66020518 |
| 26 | PRKD3 | 1.63246379 |
| 27 | ERN1 | 1.54223734 |
| 28 | PHKG2 | 1.34901827 |
| 29 | PHKG1 | 1.34901827 |
| 30 | TNIK | 1.28322896 |
| 31 | MAP3K12 | 1.28286209 |
| 32 | ADRBK2 | 1.28002441 |
| 33 | RPS6KA2 | 1.19684161 |
| 34 | CSNK1E | 1.18389029 |
| 35 | GRK1 | 1.10786935 |
| 36 | MAP2K7 | 1.05938369 |
| 37 | MINK1 | 1.05159566 |
| 38 | TLK1 | 1.02048313 |
| 39 | ALK | 1.01749985 |
| 40 | BMPR1B | 0.95598356 |
| 41 | MARK1 | 0.89377190 |
| 42 | NTRK3 | 0.88224536 |
| 43 | PNCK | 0.84785290 |
| 44 | UHMK1 | 0.81227131 |
| 45 | CAMK1 | 0.80353309 |
| 46 | PRKCG | 0.78372318 |
| 47 | RPS6KB1 | 0.78130633 |
| 48 | TAOK3 | 0.76204387 |
| 49 | PRKCZ | 0.75361894 |
| 50 | MAP3K2 | 0.73539979 |
| 51 | PRKAA1 | 0.72790681 |
| 52 | NTRK2 | 0.70393678 |
| 53 | PRKCE | 0.70043694 |
| 54 | MARK3 | 0.67681640 |
| 55 | RPS6KA6 | 0.67369085 |
| 56 | KIT | 0.65854434 |
| 57 | DMPK | 0.61466877 |
| 58 | SGK1 | 0.60703232 |
| 59 | WNK4 | 0.59520490 |
| 60 | RPS6KC1 | 0.56776656 |
| 61 | RPS6KL1 | 0.56776656 |
| 62 | OXSR1 | 0.55500560 |
| 63 | DAPK2 | 0.55009269 |
| 64 | PAK6 | 0.54603921 |
| 65 | PIK3CA | 0.54102087 |
| 66 | CAMKK1 | 0.53601796 |
| 67 | FER | 0.52101624 |
| 68 | MAP2K1 | 0.51284036 |
| 69 | PRKD2 | 0.51012438 |
| 70 | TXK | 0.49123765 |
| 71 | MKNK1 | 0.49092374 |
| 72 | PKN1 | 0.48953661 |
| 73 | EPHA3 | 0.46538945 |
| 74 | ERBB3 | 0.45818275 |
| 75 | CSNK1A1 | 0.45053465 |
| 76 | DYRK2 | 0.44436802 |
| 77 | GSK3A | 0.43967468 |
| 78 | STK11 | 0.43233601 |
| 79 | PRKAA2 | 0.42102339 |
| 80 | PRKCI | 0.40992950 |
| 81 | BRSK1 | 0.38933245 |
| 82 | CDK5 | 0.38622977 |
| 83 | MAPK1 | 0.37476497 |
| 84 | ADRBK1 | 0.37251576 |
| 85 | MST4 | 0.37039077 |
| 86 | PRKCA | 0.36183314 |
| 87 | CSNK2A2 | 0.35198430 |
| 88 | PRKACA | 0.35088552 |
| 89 | OBSCN | 0.35087950 |
| 90 | CSNK1D | 0.32801098 |
| 91 | CAMKK2 | 0.30855685 |
| 92 | NUAK1 | 0.29720598 |
| 93 | MAP2K4 | 0.28647562 |
| 94 | TYRO3 | 0.28564045 |
| 95 | PAK4 | 0.27560091 |
| 96 | CAMK2D | 0.27327296 |
| 97 | CAMK2G | 0.26165866 |
| 98 | MARK2 | 0.25743475 |
| 99 | MYLK | 0.24568115 |
| 100 | DYRK1A | 0.24073818 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 5.74803397 |
| 2 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.72657990 |
| 3 | Cocaine addiction_Homo sapiens_hsa05030 | 3.15196559 |
| 4 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 3.07861384 |
| 5 | Circadian rhythm_Homo sapiens_hsa04710 | 2.97268581 |
| 6 | Amphetamine addiction_Homo sapiens_hsa05031 | 2.64588394 |
| 7 | Nicotine addiction_Homo sapiens_hsa05033 | 2.61632028 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.19968789 |
| 9 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 2.18736382 |
| 10 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.07172635 |
| 11 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.94868990 |
| 12 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.90649114 |
| 13 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.89476571 |
| 14 | Insulin secretion_Homo sapiens_hsa04911 | 1.79131433 |
| 15 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.78383732 |
| 16 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.77350710 |
| 17 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.61331331 |
| 18 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.53200908 |
| 19 | Circadian entrainment_Homo sapiens_hsa04713 | 1.48420587 |
| 20 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.48142091 |
| 21 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.43800125 |
| 22 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.36632102 |
| 23 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.32032263 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.28902630 |
| 25 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.27201454 |
| 26 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.26880522 |
| 27 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.25142473 |
| 28 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.21061988 |
| 29 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.17194239 |
| 30 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.17085465 |
| 31 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.16107988 |
| 32 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.11518847 |
| 33 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.05843649 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.02728545 |
| 35 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.00359846 |
| 36 | Taste transduction_Homo sapiens_hsa04742 | 0.97914123 |
| 37 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.95236444 |
| 38 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.94074407 |
| 39 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.92778600 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.91712757 |
| 41 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.91365175 |
| 42 | Histidine metabolism_Homo sapiens_hsa00340 | 0.91189975 |
| 43 | Long-term depression_Homo sapiens_hsa04730 | 0.88607460 |
| 44 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.85517628 |
| 45 | Basal transcription factors_Homo sapiens_hsa03022 | 0.85477092 |
| 46 | GABAergic synapse_Homo sapiens_hsa04727 | 0.84600948 |
| 47 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.83585777 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.81404733 |
| 49 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.77738167 |
| 50 | Salivary secretion_Homo sapiens_hsa04970 | 0.77563463 |
| 51 | Morphine addiction_Homo sapiens_hsa05032 | 0.75008805 |
| 52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.74430370 |
| 53 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.71069449 |
| 54 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.70678589 |
| 55 | Bile secretion_Homo sapiens_hsa04976 | 0.70574982 |
| 56 | Mineral absorption_Homo sapiens_hsa04978 | 0.70457098 |
| 57 | Phototransduction_Homo sapiens_hsa04744 | 0.70400286 |
| 58 | Olfactory transduction_Homo sapiens_hsa04740 | 0.69177331 |
| 59 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.69008538 |
| 60 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.68892952 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.62954274 |
| 62 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.61670266 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.60969880 |
| 64 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.59477932 |
| 65 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.59438253 |
| 66 | Renin secretion_Homo sapiens_hsa04924 | 0.59210303 |
| 67 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.59182956 |
| 68 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.58828140 |
| 69 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.57381388 |
| 70 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.57163737 |
| 71 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.55926814 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.55162500 |
| 73 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.55048019 |
| 74 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52242709 |
| 75 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.52087024 |
| 76 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.51718631 |
| 77 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.51331240 |
| 78 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.51091946 |
| 79 | Parkinsons disease_Homo sapiens_hsa05012 | 0.50014236 |
| 80 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.49718746 |
| 81 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.46035791 |
| 82 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44473005 |
| 83 | Peroxisome_Homo sapiens_hsa04146 | 0.42147878 |
| 84 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.42133918 |
| 85 | Retinol metabolism_Homo sapiens_hsa00830 | 0.41800399 |
| 86 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.41014614 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.40907279 |
| 88 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.38377951 |
| 89 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.37521734 |
| 90 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.37380108 |
| 91 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.35539316 |
| 92 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.34731126 |
| 93 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.34569310 |
| 94 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.34416611 |
| 95 | Axon guidance_Homo sapiens_hsa04360 | 0.33336273 |
| 96 | Huntingtons disease_Homo sapiens_hsa05016 | 0.32910828 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.32786629 |
| 98 | Lysine degradation_Homo sapiens_hsa00310 | 0.27872138 |
| 99 | Alcoholism_Homo sapiens_hsa05034 | 0.26748612 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.24819484 |

