

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.58605490 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.58605490 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 6.45768020 |
| 4 | viral transcription (GO:0019083) | 6.42404525 |
| 5 | translational termination (GO:0006415) | 6.20502900 |
| 6 | ribosomal small subunit biogenesis (GO:0042274) | 6.14830254 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.89222030 |
| 8 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.73532520 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.47298871 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 5.38153513 |
| 11 | protein targeting to ER (GO:0045047) | 5.37859501 |
| 12 | translational elongation (GO:0006414) | 5.37523927 |
| 13 | GTP biosynthetic process (GO:0006183) | 5.28334124 |
| 14 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.26857389 |
| 15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.26857389 |
| 16 | NADH dehydrogenase complex assembly (GO:0010257) | 5.26857389 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 5.25267248 |
| 18 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.21320948 |
| 19 | protein complex biogenesis (GO:0070271) | 5.01855456 |
| 20 | protein localization to endoplasmic reticulum (GO:0070972) | 5.01200640 |
| 21 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.87994453 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.87061375 |
| 23 | maturation of SSU-rRNA (GO:0030490) | 4.72299633 |
| 24 | viral life cycle (GO:0019058) | 4.63584837 |
| 25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.52975487 |
| 26 | cellular protein complex disassembly (GO:0043624) | 4.51115716 |
| 27 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.46347841 |
| 28 | UTP biosynthetic process (GO:0006228) | 4.44482858 |
| 29 | translational initiation (GO:0006413) | 4.41278085 |
| 30 | respiratory electron transport chain (GO:0022904) | 4.31001107 |
| 31 | electron transport chain (GO:0022900) | 4.28348923 |
| 32 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.28270891 |
| 33 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.22949592 |
| 34 | response to xenobiotic stimulus (GO:0009410) | 4.09725408 |
| 35 | UTP metabolic process (GO:0046051) | 4.08691723 |
| 36 | behavioral response to nicotine (GO:0035095) | 4.03644393 |
| 37 | collecting duct development (GO:0072044) | 4.01768467 |
| 38 | ATP biosynthetic process (GO:0006754) | 3.96671975 |
| 39 | platelet dense granule organization (GO:0060155) | 3.91848120 |
| 40 | urate metabolic process (GO:0046415) | 3.90139050 |
| 41 | translation (GO:0006412) | 3.87913663 |
| 42 | ribosomal large subunit biogenesis (GO:0042273) | 3.73147563 |
| 43 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.64158194 |
| 44 | nonmotile primary cilium assembly (GO:0035058) | 3.60574231 |
| 45 | protein complex disassembly (GO:0043241) | 3.59340283 |
| 46 | response to pheromone (GO:0019236) | 3.55336637 |
| 47 | protein targeting to membrane (GO:0006612) | 3.52187693 |
| 48 | cellular component biogenesis (GO:0044085) | 3.50870194 |
| 49 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.48497079 |
| 50 | protein neddylation (GO:0045116) | 3.47490089 |
| 51 | CTP metabolic process (GO:0046036) | 3.45944480 |
| 52 | CTP biosynthetic process (GO:0006241) | 3.45944480 |
| 53 | kidney morphogenesis (GO:0060993) | 3.42514122 |
| 54 | peptidyl-histidine modification (GO:0018202) | 3.37223133 |
| 55 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.35499687 |
| 56 | macromolecular complex disassembly (GO:0032984) | 3.33332858 |
| 57 | respiratory chain complex IV assembly (GO:0008535) | 3.31495908 |
| 58 | mRNA catabolic process (GO:0006402) | 3.25557963 |
| 59 | metanephric tubule development (GO:0072170) | 3.25485719 |
| 60 | metanephric nephron tubule development (GO:0072234) | 3.25485719 |
| 61 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.20883115 |
| 62 | nephron tubule morphogenesis (GO:0072078) | 3.19758003 |
| 63 | nephron epithelium morphogenesis (GO:0072088) | 3.19758003 |
| 64 | hydrogen ion transmembrane transport (GO:1902600) | 3.19378149 |
| 65 | cartilage morphogenesis (GO:0060536) | 3.16495358 |
| 66 | cullin deneddylation (GO:0010388) | 3.16336292 |
| 67 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.13236791 |
| 68 | nephron tubule development (GO:0072080) | 3.11934174 |
| 69 | mitochondrion morphogenesis (GO:0070584) | 3.11455049 |
| 70 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.10733421 |
| 71 | respiratory tube development (GO:0030323) | 3.10279641 |
| 72 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.07839966 |
| 73 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.07550174 |
| 74 | termination of RNA polymerase III transcription (GO:0006386) | 3.06790029 |
| 75 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.06790029 |
| 76 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.04877877 |
| 77 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.04877877 |
| 78 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.01560818 |
| 79 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.00508516 |
| 80 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.00379359 |
| 81 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.95517990 |
| 82 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.94342356 |
| 83 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.94233148 |
| 84 | RNA catabolic process (GO:0006401) | 2.94099162 |
| 85 | establishment of tissue polarity (GO:0007164) | 2.93663429 |
| 86 | establishment of planar polarity (GO:0001736) | 2.93663429 |
| 87 | cornea development in camera-type eye (GO:0061303) | 2.92828756 |
| 88 | lung epithelium development (GO:0060428) | 2.90055058 |
| 89 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.88504260 |
| 90 | regulation of immunoglobulin secretion (GO:0051023) | 2.88138065 |
| 91 | intracellular protein transmembrane import (GO:0044743) | 2.87613090 |
| 92 | proton transport (GO:0015992) | 2.87125316 |
| 93 | renal tubule development (GO:0061326) | 2.85791284 |
| 94 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.84266287 |
| 95 | protein deneddylation (GO:0000338) | 2.84206261 |
| 96 | protein-cofactor linkage (GO:0018065) | 2.82373393 |
| 97 | cytochrome complex assembly (GO:0017004) | 2.79798725 |
| 98 | hydrogen transport (GO:0006818) | 2.79513267 |
| 99 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.78305977 |
| 100 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.76985831 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.51764949 |
| 2 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.03069798 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.90717789 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.69985827 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.55833618 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.45830548 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.36952382 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01014547 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.87536084 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.81220259 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.78676376 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.64071998 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.36184828 |
| 14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.19298354 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.09387793 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.99569529 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 1.99484767 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.94505212 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.93220413 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.90098387 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.86204177 |
| 22 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.86039134 |
| 23 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.85353108 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80723134 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.70928803 |
| 26 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.69957106 |
| 27 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.64499586 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.63973404 |
| 29 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.62766713 |
| 30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.59676317 |
| 31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.58361891 |
| 32 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.57299251 |
| 33 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.56483214 |
| 34 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.55434799 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.54317293 |
| 36 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.54022312 |
| 37 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.51044125 |
| 38 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.48764428 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.45998533 |
| 40 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.43310018 |
| 41 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.42695503 |
| 42 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.40161434 |
| 43 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.34154036 |
| 44 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33957927 |
| 45 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.29057103 |
| 46 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.29057103 |
| 47 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.28376202 |
| 48 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.26273429 |
| 49 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.25886289 |
| 50 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.25864764 |
| 51 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.25461818 |
| 52 | P300_19829295_ChIP-Seq_ESCs_Human | 1.19959895 |
| 53 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.19190135 |
| 54 | ERA_21632823_ChIP-Seq_H3396_Human | 1.18335343 |
| 55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.15032642 |
| 56 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.13903582 |
| 57 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.13665543 |
| 58 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13653639 |
| 59 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.13138932 |
| 60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.12241602 |
| 61 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.11445223 |
| 62 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.11408146 |
| 63 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.10581885 |
| 64 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.09914251 |
| 65 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09698159 |
| 66 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.09588139 |
| 67 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08444947 |
| 68 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.08145628 |
| 69 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.07279592 |
| 70 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.07164571 |
| 71 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.06365606 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06144263 |
| 73 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06144263 |
| 74 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.03861481 |
| 75 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.02549757 |
| 76 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.01426107 |
| 77 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.00634122 |
| 78 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.98391184 |
| 79 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98240125 |
| 80 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.97035364 |
| 81 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.96495458 |
| 82 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.96495458 |
| 83 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.96380833 |
| 84 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.94268370 |
| 85 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.93828405 |
| 86 | NCOR_22424771_ChIP-Seq_293T_Human | 0.93790536 |
| 87 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.92778218 |
| 88 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.92314946 |
| 89 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.89259168 |
| 90 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88545411 |
| 91 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.88378870 |
| 92 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.86216703 |
| 93 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.86064167 |
| 94 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.84836131 |
| 95 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.84656322 |
| 96 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.83787765 |
| 97 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.83693820 |
| 98 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.80908368 |
| 99 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.79821592 |
| 100 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.79453555 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.40440742 |
| 2 | MP0005646_abnormal_pituitary_gland | 3.95555188 |
| 3 | MP0002163_abnormal_gland_morphology | 3.84623229 |
| 4 | MP0002102_abnormal_ear_morphology | 3.49509266 |
| 5 | MP0003195_calcinosis | 2.91753907 |
| 6 | MP0005379_endocrine/exocrine_gland_phen | 2.87463109 |
| 7 | MP0000372_irregular_coat_pigmentation | 2.86820808 |
| 8 | MP0003283_abnormal_digestive_organ | 2.66829217 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.59563174 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.40832856 |
| 11 | MP0001485_abnormal_pinna_reflex | 2.37883562 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.27543047 |
| 13 | MP0002653_abnormal_ependyma_morphology | 2.17953727 |
| 14 | MP0003011_delayed_dark_adaptation | 1.93857875 |
| 15 | MP0003786_premature_aging | 1.93329365 |
| 16 | MP0002938_white_spotting | 1.81878129 |
| 17 | MP0003878_abnormal_ear_physiology | 1.79954890 |
| 18 | MP0005377_hearing/vestibular/ear_phenot | 1.79954890 |
| 19 | MP0001986_abnormal_taste_sensitivity | 1.77873586 |
| 20 | MP0002837_dystrophic_cardiac_calcinosis | 1.77687364 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.72850633 |
| 22 | MP0008872_abnormal_physiological_respon | 1.72087323 |
| 23 | MP0002277_abnormal_respiratory_mucosa | 1.65024252 |
| 24 | MP0008789_abnormal_olfactory_epithelium | 1.64750954 |
| 25 | MP0005551_abnormal_eye_electrophysiolog | 1.64501500 |
| 26 | MP0003186_abnormal_redox_activity | 1.61262301 |
| 27 | MP0003787_abnormal_imprinting | 1.60218092 |
| 28 | MP0003136_yellow_coat_color | 1.59912008 |
| 29 | MP0004885_abnormal_endolymph | 1.56888284 |
| 30 | MP0010030_abnormal_orbit_morphology | 1.56661336 |
| 31 | MP0001346_abnormal_lacrimal_gland | 1.55034811 |
| 32 | MP0000049_abnormal_middle_ear | 1.49835633 |
| 33 | MP0009384_cardiac_valve_regurgitation | 1.49136845 |
| 34 | MP0005645_abnormal_hypothalamus_physiol | 1.48894705 |
| 35 | MP0008875_abnormal_xenobiotic_pharmacok | 1.48213274 |
| 36 | MP0008995_early_reproductive_senescence | 1.47279777 |
| 37 | MP0008775_abnormal_heart_ventricle | 1.41492829 |
| 38 | MP0003693_abnormal_embryo_hatching | 1.41111440 |
| 39 | MP0002272_abnormal_nervous_system | 1.40459651 |
| 40 | MP0004142_abnormal_muscle_tone | 1.35583843 |
| 41 | MP0001984_abnormal_olfaction | 1.33667186 |
| 42 | MP0003646_muscle_fatigue | 1.30210967 |
| 43 | MP0002876_abnormal_thyroid_physiology | 1.27601782 |
| 44 | MP0001529_abnormal_vocalization | 1.25677070 |
| 45 | MP0002095_abnormal_skin_pigmentation | 1.23956701 |
| 46 | MP0002160_abnormal_reproductive_system | 1.23030582 |
| 47 | MP0002638_abnormal_pupillary_reflex | 1.18703226 |
| 48 | MP0009745_abnormal_behavioral_response | 1.15345284 |
| 49 | MP0005499_abnormal_olfactory_system | 1.14998064 |
| 50 | MP0005394_taste/olfaction_phenotype | 1.14998064 |
| 51 | MP0006036_abnormal_mitochondrial_physio | 1.14647932 |
| 52 | MP0003942_abnormal_urinary_system | 1.13122537 |
| 53 | MP0003938_abnormal_ear_development | 1.12815503 |
| 54 | MP0001905_abnormal_dopamine_level | 1.12547014 |
| 55 | MP0000631_abnormal_neuroendocrine_gland | 1.12484280 |
| 56 | MP0000026_abnormal_inner_ear | 1.11602836 |
| 57 | MP0003123_paternal_imprinting | 1.10234881 |
| 58 | MP0003119_abnormal_digestive_system | 1.10117040 |
| 59 | MP0001293_anophthalmia | 1.08904529 |
| 60 | MP0005253_abnormal_eye_physiology | 1.08142911 |
| 61 | MP0005389_reproductive_system_phenotype | 1.02126285 |
| 62 | MP0009053_abnormal_anal_canal | 0.99835993 |
| 63 | MP0006035_abnormal_mitochondrial_morpho | 0.95638153 |
| 64 | MP0001968_abnormal_touch/_nociception | 0.94521013 |
| 65 | MP0009046_muscle_twitch | 0.94076567 |
| 66 | MP0002234_abnormal_pharynx_morphology | 0.92036285 |
| 67 | MP0002295_abnormal_pulmonary_circulatio | 0.90047358 |
| 68 | MP0004742_abnormal_vestibular_system | 0.89700310 |
| 69 | MP0005636_abnormal_mineral_homeostasis | 0.88863771 |
| 70 | MP0005410_abnormal_fertilization | 0.87275434 |
| 71 | MP0005195_abnormal_posterior_eye | 0.86418910 |
| 72 | MP0010386_abnormal_urinary_bladder | 0.86392592 |
| 73 | MP0005332_abnormal_amino_acid | 0.85577626 |
| 74 | MP0001486_abnormal_startle_reflex | 0.85428545 |
| 75 | MP0009780_abnormal_chondrocyte_physiolo | 0.81752882 |
| 76 | MP0001502_abnormal_circadian_rhythm | 0.80905510 |
| 77 | MP0002736_abnormal_nociception_after | 0.80113025 |
| 78 | MP0002928_abnormal_bile_duct | 0.78473922 |
| 79 | MP0008058_abnormal_DNA_repair | 0.77095698 |
| 80 | MP0002210_abnormal_sex_determination | 0.75132950 |
| 81 | MP0002064_seizures | 0.73454870 |
| 82 | MP0001963_abnormal_hearing_physiology | 0.73318737 |
| 83 | MP0004145_abnormal_muscle_electrophysio | 0.73186849 |
| 84 | MP0005360_urolithiasis | 0.72385040 |
| 85 | MP0009643_abnormal_urine_homeostasis | 0.72359882 |
| 86 | MP0001119_abnormal_female_reproductive | 0.70932955 |
| 87 | MP0003936_abnormal_reproductive_system | 0.70784581 |
| 88 | MP0001501_abnormal_sleep_pattern | 0.70610894 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.70547721 |
| 90 | MP0005423_abnormal_somatic_nervous | 0.69319644 |
| 91 | MP0002572_abnormal_emotion/affect_behav | 0.67679238 |
| 92 | MP0003567_abnormal_fetal_cardiomyocyte | 0.67086556 |
| 93 | MP0002557_abnormal_social/conspecific_i | 0.66498856 |
| 94 | MP0001145_abnormal_male_reproductive | 0.65775705 |
| 95 | MP0000230_abnormal_systemic_arterial | 0.64458720 |
| 96 | MP0001440_abnormal_grooming_behavior | 0.64245625 |
| 97 | MP0001727_abnormal_embryo_implantation | 0.63479854 |
| 98 | MP0009764_decreased_sensitivity_to | 0.63380496 |
| 99 | MP0000653_abnormal_sex_gland | 0.63094957 |
| 100 | MP0005391_vision/eye_phenotype | 0.62983231 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.00680318 |
| 2 | Progressive macrocephaly (HP:0004481) | 4.38778456 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.38087741 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.35505909 |
| 5 | Increased CSF lactate (HP:0002490) | 4.09709987 |
| 6 | Acute encephalopathy (HP:0006846) | 4.00548686 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.78866562 |
| 8 | Hepatic necrosis (HP:0002605) | 3.70977118 |
| 9 | Septo-optic dysplasia (HP:0100842) | 3.56834273 |
| 10 | Reticulocytopenia (HP:0001896) | 3.56187814 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.49482908 |
| 12 | Methylmalonic acidemia (HP:0002912) | 3.46606070 |
| 13 | Macrocytic anemia (HP:0001972) | 3.43025148 |
| 14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.32938432 |
| 15 | Cerebral edema (HP:0002181) | 3.18579393 |
| 16 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.10539534 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.03860603 |
| 18 | Pendular nystagmus (HP:0012043) | 2.99646133 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.96975753 |
| 20 | Increased hepatocellular lipid droplets (HP:0006565) | 2.94151891 |
| 21 | Hyperglycinemia (HP:0002154) | 2.91352997 |
| 22 | Increased serum lactate (HP:0002151) | 2.85320541 |
| 23 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.75193553 |
| 24 | Methylmalonic aciduria (HP:0012120) | 2.72767716 |
| 25 | Decreased central vision (HP:0007663) | 2.70547168 |
| 26 | Lactic acidosis (HP:0003128) | 2.66233185 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.59429886 |
| 28 | Abolished electroretinogram (ERG) (HP:0000550) | 2.54825012 |
| 29 | Exertional dyspnea (HP:0002875) | 2.52844340 |
| 30 | Optic disc pallor (HP:0000543) | 2.51306865 |
| 31 | Abnormality of purine metabolism (HP:0004352) | 2.49384996 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.46953987 |
| 33 | Renal Fanconi syndrome (HP:0001994) | 2.45904229 |
| 34 | True hermaphroditism (HP:0010459) | 2.45389485 |
| 35 | Dyschromatopsia (HP:0007641) | 2.45367967 |
| 36 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.45221169 |
| 37 | Abnormality of vitamin B metabolism (HP:0004340) | 2.42129400 |
| 38 | Respiratory failure (HP:0002878) | 2.40893305 |
| 39 | Large for gestational age (HP:0001520) | 2.38987527 |
| 40 | Lethargy (HP:0001254) | 2.35780100 |
| 41 | Pancreatic fibrosis (HP:0100732) | 2.32028264 |
| 42 | Nephronophthisis (HP:0000090) | 2.30986741 |
| 43 | Pallor (HP:0000980) | 2.29738066 |
| 44 | Leukodystrophy (HP:0002415) | 2.26564354 |
| 45 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.24147476 |
| 46 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.24147476 |
| 47 | Dicarboxylic aciduria (HP:0003215) | 2.22850948 |
| 48 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.22850948 |
| 49 | Abnormality of midbrain morphology (HP:0002418) | 2.22621188 |
| 50 | Molar tooth sign on MRI (HP:0002419) | 2.22621188 |
| 51 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.22048502 |
| 52 | Absent/shortened dynein arms (HP:0200106) | 2.22048502 |
| 53 | Hypoplasia of the ulna (HP:0003022) | 2.20070334 |
| 54 | Stenosis of the external auditory canal (HP:0000402) | 2.17220598 |
| 55 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.16391340 |
| 56 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.15815582 |
| 57 | Renal cortical cysts (HP:0000803) | 2.12635506 |
| 58 | Asplenia (HP:0001746) | 2.11604605 |
| 59 | Stomatitis (HP:0010280) | 2.11299045 |
| 60 | Agitation (HP:0000713) | 2.08894362 |
| 61 | Medial flaring of the eyebrow (HP:0010747) | 2.07704132 |
| 62 | Nausea (HP:0002018) | 2.05499557 |
| 63 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.05072335 |
| 64 | Pancreatic cysts (HP:0001737) | 2.05039871 |
| 65 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.03338448 |
| 66 | Maternal diabetes (HP:0009800) | 2.01183531 |
| 67 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.00942847 |
| 68 | Hypomagnesemia (HP:0002917) | 1.95534001 |
| 69 | Constricted visual fields (HP:0001133) | 1.95408803 |
| 70 | Attenuation of retinal blood vessels (HP:0007843) | 1.94694659 |
| 71 | Hypoplastic left heart (HP:0004383) | 1.94157244 |
| 72 | Congenital, generalized hypertrichosis (HP:0004540) | 1.94149104 |
| 73 | Exercise intolerance (HP:0003546) | 1.93064242 |
| 74 | Abnormality of the renal medulla (HP:0100957) | 1.92418708 |
| 75 | Abnormal hair whorl (HP:0010721) | 1.91600855 |
| 76 | Increased intramyocellular lipid droplets (HP:0012240) | 1.90652409 |
| 77 | Colon cancer (HP:0003003) | 1.90377175 |
| 78 | Long nose (HP:0003189) | 1.87169386 |
| 79 | Abnormality of the renal cortex (HP:0011035) | 1.86988300 |
| 80 | Abnormality of urine glucose concentration (HP:0011016) | 1.86754806 |
| 81 | Glycosuria (HP:0003076) | 1.86754806 |
| 82 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.86367905 |
| 83 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.85454993 |
| 84 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.85402708 |
| 85 | Absent septum pellucidum (HP:0001331) | 1.85047293 |
| 86 | Chorioretinal atrophy (HP:0000533) | 1.82636049 |
| 87 | Confusion (HP:0001289) | 1.79883839 |
| 88 | Microvesicular hepatic steatosis (HP:0001414) | 1.79710699 |
| 89 | Optic nerve hypoplasia (HP:0000609) | 1.76921534 |
| 90 | Abnormality of magnesium homeostasis (HP:0004921) | 1.76751617 |
| 91 | Anencephaly (HP:0002323) | 1.75920284 |
| 92 | Adactyly (HP:0009776) | 1.75084860 |
| 93 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.73042796 |
| 94 | Type II lissencephaly (HP:0007260) | 1.72620742 |
| 95 | Sclerocornea (HP:0000647) | 1.71809263 |
| 96 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.71031714 |
| 97 | Abnormality of the vertebral endplates (HP:0005106) | 1.68951894 |
| 98 | Forearm undergrowth (HP:0009821) | 1.67856862 |
| 99 | Abnormality of renal resorption (HP:0011038) | 1.65961934 |
| 100 | Abnormality of serum amino acid levels (HP:0003112) | 1.63886062 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME2 | 3.33239806 |
| 2 | NME1 | 2.72480815 |
| 3 | WNK4 | 2.61883216 |
| 4 | TXK | 2.56572933 |
| 5 | PINK1 | 2.56129873 |
| 6 | NUAK1 | 2.51958492 |
| 7 | SMG1 | 2.46778818 |
| 8 | STK39 | 2.31502301 |
| 9 | ADRBK2 | 2.21760421 |
| 10 | VRK2 | 2.13684214 |
| 11 | FRK | 2.09088838 |
| 12 | STK16 | 2.07560833 |
| 13 | PDK2 | 2.07458918 |
| 14 | GRK1 | 2.02581593 |
| 15 | TSSK6 | 2.01202156 |
| 16 | OXSR1 | 1.91943829 |
| 17 | PBK | 1.85338393 |
| 18 | ZAK | 1.80640814 |
| 19 | CDC7 | 1.78725333 |
| 20 | TLK1 | 1.67728756 |
| 21 | MAP4K2 | 1.67675229 |
| 22 | VRK1 | 1.64198303 |
| 23 | WNK3 | 1.64054966 |
| 24 | PLK4 | 1.62687588 |
| 25 | BCKDK | 1.62089168 |
| 26 | MAPK15 | 1.53803035 |
| 27 | MAP3K9 | 1.43036399 |
| 28 | MST4 | 1.40807800 |
| 29 | PASK | 1.35184167 |
| 30 | CDK19 | 1.33182189 |
| 31 | EIF2AK1 | 1.27840955 |
| 32 | MAP2K6 | 1.22741818 |
| 33 | ADRBK1 | 1.22717454 |
| 34 | PLK3 | 1.22186402 |
| 35 | IRAK4 | 1.22163230 |
| 36 | NEK1 | 1.19233232 |
| 37 | BMPR1B | 1.17553905 |
| 38 | PAK3 | 1.09546108 |
| 39 | TAF1 | 1.08651796 |
| 40 | EPHA4 | 1.08044864 |
| 41 | PKN1 | 1.05920169 |
| 42 | CAMK1 | 1.05614000 |
| 43 | DYRK2 | 1.02278666 |
| 44 | MAP4K1 | 1.00012167 |
| 45 | KIT | 0.97867675 |
| 46 | INSRR | 0.96853124 |
| 47 | LRRK2 | 0.86689840 |
| 48 | TEC | 0.86665428 |
| 49 | TIE1 | 0.85981733 |
| 50 | DYRK1B | 0.84964825 |
| 51 | ARAF | 0.82585066 |
| 52 | CSNK1G2 | 0.80263815 |
| 53 | RPS6KA5 | 0.79694102 |
| 54 | ERBB3 | 0.77881601 |
| 55 | PAK2 | 0.77859826 |
| 56 | BUB1 | 0.75001389 |
| 57 | TNIK | 0.72864769 |
| 58 | MKNK1 | 0.72359682 |
| 59 | NTRK2 | 0.70826942 |
| 60 | CSNK2A2 | 0.70724797 |
| 61 | SRPK1 | 0.66276751 |
| 62 | CSNK2A1 | 0.65453533 |
| 63 | AKT2 | 0.62213709 |
| 64 | PIK3CA | 0.61950292 |
| 65 | AURKB | 0.61312643 |
| 66 | ACVR1B | 0.60741016 |
| 67 | CSNK1G3 | 0.57792651 |
| 68 | STK11 | 0.57698185 |
| 69 | PRKCE | 0.57198091 |
| 70 | PRKCG | 0.56088374 |
| 71 | WNK1 | 0.54643965 |
| 72 | EIF2AK3 | 0.54562588 |
| 73 | PRKACA | 0.53987559 |
| 74 | MOS | 0.53135404 |
| 75 | CSNK1G1 | 0.51446036 |
| 76 | PLK2 | 0.51225613 |
| 77 | ITK | 0.50417751 |
| 78 | IRAK1 | 0.48524623 |
| 79 | CAMK2A | 0.48280210 |
| 80 | TGFBR1 | 0.46046640 |
| 81 | OBSCN | 0.45407135 |
| 82 | PRKCA | 0.45335153 |
| 83 | ATR | 0.44895380 |
| 84 | MAPKAPK5 | 0.44290011 |
| 85 | PHKG2 | 0.44023780 |
| 86 | PHKG1 | 0.44023780 |
| 87 | ABL2 | 0.42498837 |
| 88 | PRKCQ | 0.41344937 |
| 89 | PRKCZ | 0.40993873 |
| 90 | AURKA | 0.40935223 |
| 91 | PRKCD | 0.40645688 |
| 92 | CSNK1E | 0.40611066 |
| 93 | IKBKB | 0.38722901 |
| 94 | LYN | 0.38102207 |
| 95 | PRKG1 | 0.36355302 |
| 96 | CSNK1A1L | 0.35676889 |
| 97 | SIK2 | 0.34015346 |
| 98 | DAPK3 | 0.33994161 |
| 99 | CHEK2 | 0.33184903 |
| 100 | RPS6KA1 | 0.32721017 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.23002114 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.17965493 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.68065733 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.60148238 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.70209315 |
| 6 | Sulfur relay system_Homo sapiens_hsa04122 | 2.50089190 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.47048097 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 2.44424391 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.34741016 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.31481991 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.23469328 |
| 12 | Asthma_Homo sapiens_hsa05310 | 2.22182259 |
| 13 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.07429982 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.91816142 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.85052912 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.83258175 |
| 17 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.79871842 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.77267471 |
| 19 | Mismatch repair_Homo sapiens_hsa03430 | 1.57435411 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.51062103 |
| 21 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.48272530 |
| 22 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.43809383 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.35731628 |
| 24 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.34726915 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.28950442 |
| 26 | DNA replication_Homo sapiens_hsa03030 | 1.27989787 |
| 27 | Phototransduction_Homo sapiens_hsa04744 | 1.27395912 |
| 28 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.21488277 |
| 29 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.18891534 |
| 30 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16761522 |
| 31 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.14315771 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.13615263 |
| 33 | Allograft rejection_Homo sapiens_hsa05330 | 1.12562345 |
| 34 | Purine metabolism_Homo sapiens_hsa00230 | 1.10528188 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.09621126 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.09396260 |
| 37 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.09311445 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.98933187 |
| 39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.98634437 |
| 40 | Peroxisome_Homo sapiens_hsa04146 | 0.98311793 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 0.97370727 |
| 42 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.96088199 |
| 43 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.95521399 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.93751244 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89243459 |
| 46 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.88442769 |
| 47 | Retinol metabolism_Homo sapiens_hsa00830 | 0.85671460 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.84302041 |
| 49 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.83113649 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.80296396 |
| 51 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.76200184 |
| 52 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.76132283 |
| 53 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.75904657 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.73254100 |
| 55 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.70858377 |
| 56 | Spliceosome_Homo sapiens_hsa03040 | 0.69930981 |
| 57 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.69909690 |
| 58 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.68324816 |
| 59 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65171448 |
| 60 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.64416587 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62865469 |
| 62 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.61373230 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.60938829 |
| 64 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.60616174 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.58949919 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.58812405 |
| 67 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.57613593 |
| 68 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56311795 |
| 69 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55377083 |
| 70 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.54011674 |
| 71 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.52686662 |
| 72 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.50635148 |
| 73 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.46363683 |
| 74 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.45979051 |
| 75 | Salivary secretion_Homo sapiens_hsa04970 | 0.44764551 |
| 76 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44715436 |
| 77 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.43741111 |
| 78 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.43273074 |
| 79 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.41217993 |
| 80 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.40454146 |
| 81 | Morphine addiction_Homo sapiens_hsa05032 | 0.38594799 |
| 82 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.38468211 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.37238806 |
| 84 | Insulin secretion_Homo sapiens_hsa04911 | 0.36834459 |
| 85 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.36611305 |
| 86 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.36515927 |
| 87 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.35846989 |
| 88 | Nicotine addiction_Homo sapiens_hsa05033 | 0.35378789 |
| 89 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.35189861 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.34892991 |
| 91 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32581839 |
| 92 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.32024287 |
| 93 | Taste transduction_Homo sapiens_hsa04742 | 0.31731043 |
| 94 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30579791 |
| 95 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.30070589 |
| 96 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.28087228 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.27643779 |
| 98 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.27399487 |
| 99 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.22624211 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.22570233 |

