RPL13P

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)8.12283266
2ribosomal small subunit biogenesis (GO:0042274)7.86472509
3translational termination (GO:0006415)7.81290619
4ribosomal small subunit assembly (GO:0000028)7.27370926
5translational elongation (GO:0006414)6.54271061
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.42039492
7maturation of SSU-rRNA (GO:0030490)6.41449773
8cotranslational protein targeting to membrane (GO:0006613)6.38655195
9protein targeting to ER (GO:0045047)6.31001836
10establishment of protein localization to endoplasmic reticulum (GO:0072599)6.07454573
11viral life cycle (GO:0019058)6.06848608
12protein localization to endoplasmic reticulum (GO:0070972)5.90987840
13cellular protein complex disassembly (GO:0043624)5.86016630
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.66233747
15protein complex disassembly (GO:0043241)5.08466766
16behavioral response to nicotine (GO:0035095)5.05834411
17translational initiation (GO:0006413)4.89565449
18macromolecular complex disassembly (GO:0032984)4.79653920
19ribosomal large subunit biogenesis (GO:0042273)4.35118024
20protein targeting to membrane (GO:0006612)4.33195457
21ATP synthesis coupled proton transport (GO:0015986)4.16491652
22energy coupled proton transport, down electrochemical gradient (GO:0015985)4.16491652
23cell proliferation in forebrain (GO:0021846)4.12538408
24chaperone-mediated protein transport (GO:0072321)3.97440366
25ribonucleoprotein complex biogenesis (GO:0022613)3.93998877
26nuclear-transcribed mRNA catabolic process (GO:0000956)3.90829828
27protein neddylation (GO:0045116)3.88627201
28translation (GO:0006412)3.84486899
29base-excision repair, AP site formation (GO:0006285)3.82472777
30pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.77618230
31epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.69715045
32mRNA catabolic process (GO:0006402)3.68091544
33mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.67998907
34mitochondrial respiratory chain complex I assembly (GO:0032981)3.67998907
35NADH dehydrogenase complex assembly (GO:0010257)3.67998907
36cellular component biogenesis (GO:0044085)3.65224509
37substrate-independent telencephalic tangential migration (GO:0021826)3.52875445
38substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.52875445
39GTP biosynthetic process (GO:0006183)3.52806475
40auditory receptor cell differentiation (GO:0042491)3.45048003
41pyrimidine nucleotide catabolic process (GO:0006244)3.43698420
42protein complex biogenesis (GO:0070271)3.40026059
43negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.36046570
44mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.34231328
45RNA catabolic process (GO:0006401)3.32618344
46establishment of protein localization to mitochondrial membrane (GO:0090151)3.31908460
47ubiquinone biosynthetic process (GO:0006744)3.22694502
48somite development (GO:0061053)3.21376202
49protein polyglutamylation (GO:0018095)3.19442734
50mitochondrial respiratory chain complex assembly (GO:0033108)3.18755546
51cardiovascular system development (GO:0072358)3.16359441
52regulation of cilium movement (GO:0003352)3.15724828
53neuron fate determination (GO:0048664)3.15169767
54central nervous system myelination (GO:0022010)3.14198281
55axon ensheathment in central nervous system (GO:0032291)3.14198281
56negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.12117106
57UTP biosynthetic process (GO:0006228)3.12004722
58mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.10443032
59detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.04609577
60sulfate transmembrane transport (GO:1902358)3.03433674
61regulation of microtubule-based movement (GO:0060632)3.02689970
62tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.01495959
63RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.01495959
64epithelial cilium movement (GO:0003351)2.96163077
65pattern specification involved in kidney development (GO:0061004)2.95598878
66UTP metabolic process (GO:0046051)2.95571609
67water-soluble vitamin biosynthetic process (GO:0042364)2.95486134
68synaptic transmission, cholinergic (GO:0007271)2.91788348
69tongue development (GO:0043586)2.91021977
70electron transport chain (GO:0022900)2.90312505
71glycerophospholipid catabolic process (GO:0046475)2.90292532
72protein targeting (GO:0006605)2.88299947
73establishment of protein localization to membrane (GO:0090150)2.88196185
74purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.85937091
75respiratory electron transport chain (GO:0022904)2.85900960
76ubiquinone metabolic process (GO:0006743)2.85786203
77sulfate transport (GO:0008272)2.82964564
78transmission of nerve impulse (GO:0019226)2.80895548
79purine nucleoside triphosphate biosynthetic process (GO:0009145)2.78150969
80DNA deamination (GO:0045006)2.77264072
81nonmotile primary cilium assembly (GO:0035058)2.73655621
82parturition (GO:0007567)2.71073629
83intraciliary transport (GO:0042073)2.69393779
84termination of RNA polymerase III transcription (GO:0006386)2.68876371
85transcription elongation from RNA polymerase III promoter (GO:0006385)2.68876371
86axonemal dynein complex assembly (GO:0070286)2.68847640
87tRNA processing (GO:0008033)2.67906665
88preassembly of GPI anchor in ER membrane (GO:0016254)2.67157195
89spinal cord association neuron differentiation (GO:0021527)2.66786040
90pseudouridine synthesis (GO:0001522)2.66499393
91ATP biosynthetic process (GO:0006754)2.64820444
92negative regulation of telomere maintenance (GO:0032205)2.63273675
93negative regulation of DNA-templated transcription, elongation (GO:0032785)2.60091142
94negative regulation of oligodendrocyte differentiation (GO:0048715)2.59522198
95rRNA metabolic process (GO:0016072)2.58827472
96nephron tubule morphogenesis (GO:0072078)2.58419541
97nephron epithelium morphogenesis (GO:0072088)2.58419541
98rRNA processing (GO:0006364)2.58331767
99hypothalamus development (GO:0021854)2.56484110
100establishment of protein localization to organelle (GO:0072594)2.56380855

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.42577770
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.40148917
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.12639523
4HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.81334591
5ZNF274_21170338_ChIP-Seq_K562_Hela2.58933445
6ETS1_20019798_ChIP-Seq_JURKAT_Human2.47286998
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.42839920
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.38961247
9NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.33224002
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.23468403
11IRF1_19129219_ChIP-ChIP_H3396_Human2.23387373
12VDR_22108803_ChIP-Seq_LS180_Human1.97612444
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.94406821
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.90198306
15RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.87320439
16TP63_19390658_ChIP-ChIP_HaCaT_Human1.84503707
17CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.83023034
18MYC_18555785_ChIP-Seq_MESCs_Mouse1.82281686
19TTF2_22483619_ChIP-Seq_HELA_Human1.71768715
20EZH2_27294783_Chip-Seq_ESCs_Mouse1.70936432
21XRN2_22483619_ChIP-Seq_HELA_Human1.70486504
22MYC_18940864_ChIP-ChIP_HL60_Human1.68960197
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.68141344
24CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.67949284
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.64436852
26EZH2_27304074_Chip-Seq_ESCs_Mouse1.62754349
27SUZ12_27294783_Chip-Seq_ESCs_Mouse1.62246182
28YY1_21170310_ChIP-Seq_MESCs_Mouse1.62059403
29SOX2_18555785_ChIP-Seq_MESCs_Mouse1.56156069
30GATA3_21878914_ChIP-Seq_MCF-7_Human1.55997224
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.51955161
32SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.51519923
33CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.51265966
34CBX2_27304074_Chip-Seq_ESCs_Mouse1.49996248
35GABP_19822575_ChIP-Seq_HepG2_Human1.48172916
36EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.44919701
37KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.43824904
38CTCF_20526341_ChIP-Seq_ESCs_Human1.41134486
39EED_16625203_ChIP-ChIP_MESCs_Mouse1.40762254
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.40173801
41VDR_23849224_ChIP-Seq_CD4+_Human1.39485451
42JARID2_20064375_ChIP-Seq_MESCs_Mouse1.38983417
43CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.37646146
44SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.36885412
45MYC_18358816_ChIP-ChIP_MESCs_Mouse1.36742490
46EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.33860858
47TP53_22573176_ChIP-Seq_HFKS_Human1.33156566
48BMI1_23680149_ChIP-Seq_NPCS_Mouse1.32212639
49REST_21632747_ChIP-Seq_MESCs_Mouse1.32197962
50ERA_21632823_ChIP-Seq_H3396_Human1.31620876
51TAF2_19829295_ChIP-Seq_ESCs_Human1.30003992
52MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.29519624
53NANOG_20526341_ChIP-Seq_ESCs_Human1.28696150
54JARID2_20075857_ChIP-Seq_MESCs_Mouse1.28523898
55PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.25847197
56FOXP3_21729870_ChIP-Seq_TREG_Human1.25300890
57CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.24391439
58NOTCH1_21737748_ChIP-Seq_TLL_Human1.24116594
59RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.23069045
60CIITA_25753668_ChIP-Seq_RAJI_Human1.21297570
61MYC_19079543_ChIP-ChIP_MESCs_Mouse1.20667822
62CTCF_18555785_ChIP-Seq_MESCs_Mouse1.20593095
63SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.19605337
64BCL6_27268052_Chip-Seq_Bcells_Human1.18191207
65RNF2_27304074_Chip-Seq_ESCs_Mouse1.17782698
66ETV2_25802403_ChIP-Seq_MESCs_Mouse1.17600235
67NCOR_22424771_ChIP-Seq_293T_Human1.16016546
68FOXP1_21924763_ChIP-Seq_HESCs_Human1.14156311
69RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.13245301
70P68_20966046_ChIP-Seq_HELA_Human1.12738384
71SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.09703987
72P53_21459846_ChIP-Seq_SAOS-2_Human1.09582815
73CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.09344471
74SRF_21415370_ChIP-Seq_HL-1_Mouse1.09332027
75POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.09097611
76E2F1_20622854_ChIP-Seq_HELA_Human1.06843213
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06469190
78REST_18959480_ChIP-ChIP_MESCs_Mouse1.06392833
79RNF2_18974828_ChIP-Seq_MESCs_Mouse1.02817918
80EZH2_18974828_ChIP-Seq_MESCs_Mouse1.02817918
81THAP11_20581084_ChIP-Seq_MESCs_Mouse1.01926272
82RNF2_27304074_Chip-Seq_NSC_Mouse1.00937482
83CTCF_27219007_Chip-Seq_Bcells_Human1.00753833
84MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.00042038
85E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.99822497
86SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98120923
87TET1_21451524_ChIP-Seq_MESCs_Mouse0.96412676
88PHF8_20622854_ChIP-Seq_HELA_Human0.96089406
89CREB1_15753290_ChIP-ChIP_HEK293T_Human0.95450548
90ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.93503232
91ELF1_20517297_ChIP-Seq_JURKAT_Human0.92547587
92YY1_22570637_ChIP-Seq_MALME-3M_Human0.92327594
93EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91476440
94TP53_20018659_ChIP-ChIP_R1E_Mouse0.91170592
95E2F1_17053090_ChIP-ChIP_MCF-7_Human0.90461759
96RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89375786
97SA1_27219007_Chip-Seq_Bcells_Human0.88355757
98AUTS2_25519132_ChIP-Seq_293T-REX_Human0.88128392
99FUS_26573619_Chip-Seq_HEK293_Human0.87763419
100ELK1_19687146_ChIP-ChIP_HELA_Human0.87654780

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.78392427
2MP0006292_abnormal_olfactory_placode4.29206518
3MP0003787_abnormal_imprinting3.36523527
4MP0003122_maternal_imprinting2.90251424
5MP0003123_paternal_imprinting2.85843623
6MP0002653_abnormal_ependyma_morphology2.84342446
7MP0008789_abnormal_olfactory_epithelium2.61963872
8MP0002163_abnormal_gland_morphology2.49353402
9MP0004142_abnormal_muscle_tone2.31280164
10MP0002138_abnormal_hepatobiliary_system2.29790540
11MP0003121_genomic_imprinting2.13869682
12MP0005394_taste/olfaction_phenotype2.05999533
13MP0005499_abnormal_olfactory_system2.05999533
14MP0001968_abnormal_touch/_nociception1.98396186
15MP0005646_abnormal_pituitary_gland1.97125481
16MP0003646_muscle_fatigue1.91139900
17MP0001293_anophthalmia1.89618390
18MP0002736_abnormal_nociception_after1.83221921
19MP0008004_abnormal_stomach_pH1.80822721
20MP0005377_hearing/vestibular/ear_phenot1.78884699
21MP0003878_abnormal_ear_physiology1.78884699
22MP0008877_abnormal_DNA_methylation1.78837122
23MP0001984_abnormal_olfaction1.71533725
24MP0000778_abnormal_nervous_system1.66833694
25MP0005379_endocrine/exocrine_gland_phen1.66374030
26MP0006276_abnormal_autonomic_nervous1.66013660
27MP0002638_abnormal_pupillary_reflex1.65361917
28MP0001986_abnormal_taste_sensitivity1.65137924
29MP0005551_abnormal_eye_electrophysiolog1.62989069
30MP0001485_abnormal_pinna_reflex1.61757959
31MP0004885_abnormal_endolymph1.58998847
32MP0000013_abnormal_adipose_tissue1.58103637
33MP0001502_abnormal_circadian_rhythm1.52462359
34MP0006072_abnormal_retinal_apoptosis1.47375929
35MP0002102_abnormal_ear_morphology1.46291774
36MP0004147_increased_porphyrin_level1.44103887
37MP0003136_yellow_coat_color1.40785823
38MP0000631_abnormal_neuroendocrine_gland1.38691358
39MP0001529_abnormal_vocalization1.37943011
40MP0000049_abnormal_middle_ear1.37914421
41MP0003879_abnormal_hair_cell1.35831742
42MP0008872_abnormal_physiological_respon1.35112942
43MP0002272_abnormal_nervous_system1.33809311
44MP0010030_abnormal_orbit_morphology1.33795827
45MP0005195_abnormal_posterior_eye1.26778127
46MP0008875_abnormal_xenobiotic_pharmacok1.26099584
47MP0002160_abnormal_reproductive_system1.24747278
48MP0002733_abnormal_thermal_nociception1.23689127
49MP0004742_abnormal_vestibular_system1.17479235
50MP0000372_irregular_coat_pigmentation1.15406843
51MP0002938_white_spotting1.15380661
52MP0002557_abnormal_social/conspecific_i1.14188007
53MP0004133_heterotaxia1.10627354
54MP0005075_abnormal_melanosome_morpholog1.07625677
55MP0009745_abnormal_behavioral_response1.05322703
56MP0000026_abnormal_inner_ear1.04187552
57MP0004145_abnormal_muscle_electrophysio1.04039733
58MP0002572_abnormal_emotion/affect_behav1.03678161
59MP0001970_abnormal_pain_threshold1.03062120
60MP0008775_abnormal_heart_ventricle1.02766638
61MP0002752_abnormal_somatic_nervous1.02456660
62MP0001440_abnormal_grooming_behavior1.02219925
63MP0005167_abnormal_blood-brain_barrier0.99957422
64MP0000955_abnormal_spinal_cord0.98624895
65MP0002210_abnormal_sex_determination0.98463955
66MP0004019_abnormal_vitamin_homeostasis0.97741600
67MP0004858_abnormal_nervous_system0.94927801
68MP0009046_muscle_twitch0.94813689
69MP0001963_abnormal_hearing_physiology0.94347884
70MP0001905_abnormal_dopamine_level0.93587204
71MP0005389_reproductive_system_phenotype0.93266125
72MP0003937_abnormal_limbs/digits/tail_de0.93255118
73MP0002735_abnormal_chemical_nociception0.92284272
74MP0002234_abnormal_pharynx_morphology0.92201624
75MP0001348_abnormal_lacrimal_gland0.92071670
76MP0002233_abnormal_nose_morphology0.91135531
77MP0005253_abnormal_eye_physiology0.89953860
78MP0002837_dystrophic_cardiac_calcinosis0.89719077
79MP0003880_abnormal_central_pattern0.88670440
80MP0002063_abnormal_learning/memory/cond0.88405510
81MP0002184_abnormal_innervation0.88203281
82MP0001486_abnormal_startle_reflex0.87557213
83MP0000566_synostosis0.86175212
84MP0002095_abnormal_skin_pigmentation0.84438736
85MP0003635_abnormal_synaptic_transmissio0.83621156
86MP0000003_abnormal_adipose_tissue0.82419022
87MP0009250_abnormal_appendicular_skeleto0.81540449
88MP0003315_abnormal_perineum_morphology0.80760808
89MP0001324_abnormal_eye_pigmentation0.80760391
90MP0002067_abnormal_sensory_capabilities0.80383878
91MP0003011_delayed_dark_adaptation0.79214577
92MP0005645_abnormal_hypothalamus_physiol0.78233983
93MP0005391_vision/eye_phenotype0.77402816
94MP0004043_abnormal_pH_regulation0.75667091
95MP0000613_abnormal_salivary_gland0.75380101
96MP0002928_abnormal_bile_duct0.74983247
97MP0004130_abnormal_muscle_cell0.74880578
98MP0009053_abnormal_anal_canal0.74071322
99MP0001145_abnormal_male_reproductive0.73995761
100MP0003567_abnormal_fetal_cardiomyocyte0.73633941

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.20987741
2Abnormality of cells of the erythroid lineage (HP:0012130)5.15771525
3Pancreatic fibrosis (HP:0100732)4.30873046
4Abnormality of midbrain morphology (HP:0002418)4.09441479
5Molar tooth sign on MRI (HP:0002419)4.09441479
6Abnormal number of erythroid precursors (HP:0012131)4.01416448
7Pancreatic cysts (HP:0001737)3.57336100
8Macrocytic anemia (HP:0001972)3.54669039
9Acute necrotizing encephalopathy (HP:0006965)3.50943955
10Type II lissencephaly (HP:0007260)3.43626858
11Absent rod-and cone-mediated responses on ERG (HP:0007688)3.32212274
12Septo-optic dysplasia (HP:0100842)3.30858227
13Aplasia/Hypoplasia of the spleen (HP:0010451)3.27982895
14Chronic hepatic failure (HP:0100626)3.24993706
15Asplenia (HP:0001746)3.18895975
16Colon cancer (HP:0003003)3.15472112
17Acute encephalopathy (HP:0006846)3.13880145
18Abnormal mitochondria in muscle tissue (HP:0008316)3.12215206
19True hermaphroditism (HP:0010459)3.10481111
20Abnormal rod and cone electroretinograms (HP:0008323)3.08367087
21Nephronophthisis (HP:0000090)2.91471005
22Mitochondrial inheritance (HP:0001427)2.83529195
23Pallor (HP:0000980)2.76647665
24Congenital stationary night blindness (HP:0007642)2.76368296
25Progressive macrocephaly (HP:0004481)2.72284111
26Cystic liver disease (HP:0006706)2.69977957
27Anterior segment dysgenesis (HP:0007700)2.69587519
28Cerebellar dysplasia (HP:0007033)2.69280636
29Bile duct proliferation (HP:0001408)2.66960626
30Abnormal biliary tract physiology (HP:0012439)2.66960626
31Abnormality of the renal medulla (HP:0100957)2.65589516
32Abnormality of the renal cortex (HP:0011035)2.62696953
33Absent thumb (HP:0009777)2.61943053
34Sclerocornea (HP:0000647)2.58613964
35Medial flaring of the eyebrow (HP:0010747)2.56369478
36Abnormal drinking behavior (HP:0030082)2.55631394
37Polydipsia (HP:0001959)2.55631394
38Aplasia/Hypoplasia of the sacrum (HP:0008517)2.50281162
39Rib fusion (HP:0000902)2.50225719
40Pendular nystagmus (HP:0012043)2.49985178
41Increased CSF lactate (HP:0002490)2.47559941
42Anophthalmia (HP:0000528)2.40494890
43Hyperglycinemia (HP:0002154)2.40411480
44Optic nerve hypoplasia (HP:0000609)2.38715221
45Dynein arm defect of respiratory motile cilia (HP:0012255)2.34895156
46Absent/shortened dynein arms (HP:0200106)2.34895156
47Anencephaly (HP:0002323)2.33574749
483-Methylglutaconic aciduria (HP:0003535)2.31064634
49Cerebral edema (HP:0002181)2.28229739
50Abnormality of the labia minora (HP:0012880)2.28076911
51Polyuria (HP:0000103)2.27024050
52Optic disc pallor (HP:0000543)2.24199451
53Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.23175116
54Hypoplasia of the radius (HP:0002984)2.21926642
55Absent septum pellucidum (HP:0001331)2.20196769
56Postaxial foot polydactyly (HP:0001830)2.16029315
57Increased hepatocellular lipid droplets (HP:0006565)2.15393772
58Congenital hepatic fibrosis (HP:0002612)2.15101851
59Depressed nasal ridge (HP:0000457)2.13331888
60Tubular atrophy (HP:0000092)2.13250486
61Stenosis of the external auditory canal (HP:0000402)2.12581594
62Renal Fanconi syndrome (HP:0001994)2.09358636
63Optic nerve coloboma (HP:0000588)2.08994478
64Lipid accumulation in hepatocytes (HP:0006561)2.08878128
65Gait imbalance (HP:0002141)2.05735202
66Supernumerary spleens (HP:0009799)2.04568167
67Hepatocellular necrosis (HP:0001404)2.03371055
68Abnormal ciliary motility (HP:0012262)2.01908480
69Lissencephaly (HP:0001339)1.98031000
70Oligodactyly (hands) (HP:0001180)1.97576171
71Congenital primary aphakia (HP:0007707)1.97153687
72Elevated erythrocyte sedimentation rate (HP:0003565)1.94267127
73Nephrogenic diabetes insipidus (HP:0009806)1.94146424
7411 pairs of ribs (HP:0000878)1.92611656
75Occipital encephalocele (HP:0002085)1.92170174
76Abnormal respiratory epithelium morphology (HP:0012253)1.90540039
77Abnormal respiratory motile cilium morphology (HP:0005938)1.90540039
78Oligodactyly (HP:0012165)1.89968909
79Pachygyria (HP:0001302)1.87975097
80Forearm undergrowth (HP:0009821)1.86637374
81Abnormality of renal resorption (HP:0011038)1.86224548
82Hypoplasia of the ulna (HP:0003022)1.81242016
83Abnormal urine output (HP:0012590)1.79559414
84Keratoconus (HP:0000563)1.78285091
85Increased corneal curvature (HP:0100692)1.78285091
86Abnormality of renal excretion (HP:0011036)1.77912112
87Increased intramyocellular lipid droplets (HP:0012240)1.77627743
88Preaxial hand polydactyly (HP:0001177)1.77566933
89Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.77111622
90Maternal diabetes (HP:0009800)1.75749264
91Decreased central vision (HP:0007663)1.75627484
92Hepatic necrosis (HP:0002605)1.75373948
93Postaxial hand polydactyly (HP:0001162)1.74840509
94Severe muscular hypotonia (HP:0006829)1.74167672
95Hyperthyroidism (HP:0000836)1.73915359
96Aplasia/Hypoplasia of the fovea (HP:0008060)1.73913547
97Hypoplasia of the fovea (HP:0007750)1.73913547
98Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.73078786
99Lactic acidosis (HP:0003128)1.72539382
100Male pseudohermaphroditism (HP:0000037)1.72331208

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK14.71734451
2ZAK4.67622615
3WNK43.95360713
4BCKDK3.82418370
5CASK3.21929715
6TIE12.69443108
7CDK192.31255799
8DYRK22.22310168
9FRK2.16099983
10LRRK22.06328492
11ADRBK22.05420981
12GRK11.95898627
13PIK3CA1.89213303
14NUAK11.87217667
15STK161.75360887
16PINK11.72608780
17STK391.58156559
18EPHA41.40666487
19MAP3K111.35129320
20PHKG21.28904414
21PHKG11.28904414
22VRK11.28477363
23WNK11.26343384
24TXK1.21906915
25PDK21.20139384
26EPHB21.16861703
27NEK11.16555165
28PRKCG1.08484901
29CAMK11.06461589
30RPS6KA51.01004204
31TAOK31.00701492
32CDC70.99885125
33PRKCQ0.96549723
34NTRK20.94647381
35CAMK1D0.94457378
36VRK20.93943341
37MAP4K20.91768640
38WNK30.91534358
39PRKCI0.90333267
40TYRO30.88482891
41PAK30.87638213
42BRAF0.86427807
43STK110.84840697
44CAMKK20.84084951
45MAP3K40.83395558
46MAP2K70.82700697
47PIM10.81526477
48CHEK20.79709711
49NME20.79407978
50NEK20.77400323
51RPS6KA60.76618612
52OXSR10.75146973
53DAPK30.74582029
54KDR0.72984834
55BMPR1B0.72320224
56DAPK20.71036121
57ADRBK10.66110621
58CAMK1G0.64724348
59AURKB0.64029100
60ABL20.59522404
61SGK2230.58112218
62SGK4940.58112218
63STK38L0.57610807
64PKN10.56978251
65RPS6KC10.56873320
66RPS6KL10.56873320
67PRKCZ0.56103547
68MARK30.55624944
69MAPK150.55157757
70PRKACA0.54677662
71MAP2K20.53889011
72AURKA0.53690059
73IKBKB0.53060105
74CSNK2A20.52822990
75MAPK130.52241875
76MKNK20.51697792
77DYRK1B0.50446904
78PLK10.49282388
79TEC0.49120588
80ARAF0.47274487
81PRKCH0.47092891
82INSRR0.46653080
83AKT20.45557613
84PLK40.45422749
85CSNK1E0.45008413
86CAMK40.44156636
87CSNK1G30.43057858
88CSNK1G20.42291588
89SIK20.40218531
90PRKCD0.39773429
91DYRK1A0.39314386
92CSNK2A10.37622865
93MUSK0.37287653
94MAP2K40.36461113
95TNIK0.33651094
96GRK50.33458813
97RPS6KA20.32363129
98PRKCA0.32030350
99RPS6KA10.30274431
100SGK10.29390661

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030107.04974340
2Oxidative phosphorylation_Homo sapiens_hsa001903.59891227
3Parkinsons disease_Homo sapiens_hsa050123.09430109
4Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.73864932
5Sulfur relay system_Homo sapiens_hsa041222.50331000
6RNA polymerase_Homo sapiens_hsa030202.48941014
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.39066464
8Cardiac muscle contraction_Homo sapiens_hsa042602.35907285
9Huntingtons disease_Homo sapiens_hsa050162.34943853
10Linoleic acid metabolism_Homo sapiens_hsa005912.19345521
11alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.10656531
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.09337935
13Alzheimers disease_Homo sapiens_hsa050102.00154732
14Base excision repair_Homo sapiens_hsa034101.92844362
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.87324566
16Butanoate metabolism_Homo sapiens_hsa006501.53106967
17Fanconi anemia pathway_Homo sapiens_hsa034601.52674569
18Pyrimidine metabolism_Homo sapiens_hsa002401.43106200
19RNA degradation_Homo sapiens_hsa030181.38204505
20Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.37445259
21Phototransduction_Homo sapiens_hsa047441.34192245
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.28799397
23Protein export_Homo sapiens_hsa030601.28269590
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.26350765
25Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.23401096
26Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.19094856
27Propanoate metabolism_Homo sapiens_hsa006401.18850022
28Systemic lupus erythematosus_Homo sapiens_hsa053221.17074603
29Nitrogen metabolism_Homo sapiens_hsa009101.14538527
30Proteasome_Homo sapiens_hsa030501.14482269
31Fat digestion and absorption_Homo sapiens_hsa049751.11610525
32Tryptophan metabolism_Homo sapiens_hsa003801.09381937
33Selenocompound metabolism_Homo sapiens_hsa004501.07912433
34Basal transcription factors_Homo sapiens_hsa030221.07491891
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.04324979
36Homologous recombination_Homo sapiens_hsa034401.00300671
37Ether lipid metabolism_Homo sapiens_hsa005650.98502512
38Arachidonic acid metabolism_Homo sapiens_hsa005900.98130899
39Peroxisome_Homo sapiens_hsa041460.96075949
40Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.93967842
41Nicotine addiction_Homo sapiens_hsa050330.92614973
42One carbon pool by folate_Homo sapiens_hsa006700.92489563
43Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.90637259
44Olfactory transduction_Homo sapiens_hsa047400.90068697
45Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.89146441
46Purine metabolism_Homo sapiens_hsa002300.86974239
47Caffeine metabolism_Homo sapiens_hsa002320.86664551
48Alcoholism_Homo sapiens_hsa050340.84704265
49Intestinal immune network for IgA production_Homo sapiens_hsa046720.82816195
50Morphine addiction_Homo sapiens_hsa050320.80756935
51Metabolic pathways_Homo sapiens_hsa011000.80384764
52Arginine and proline metabolism_Homo sapiens_hsa003300.77598548
53Basal cell carcinoma_Homo sapiens_hsa052170.77542813
54Fatty acid degradation_Homo sapiens_hsa000710.73302490
55Steroid biosynthesis_Homo sapiens_hsa001000.70966981
56Chemical carcinogenesis_Homo sapiens_hsa052040.70527238
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.69342079
58Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.68711372
59Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.67450522
60Retinol metabolism_Homo sapiens_hsa008300.64459426
61Glycerolipid metabolism_Homo sapiens_hsa005610.63688958
62Asthma_Homo sapiens_hsa053100.61696403
63Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61487429
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.61315714
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.61203233
66Nucleotide excision repair_Homo sapiens_hsa034200.61156864
67Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.61056834
68Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.59794127
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.58719072
70Hedgehog signaling pathway_Homo sapiens_hsa043400.56185434
71RNA transport_Homo sapiens_hsa030130.52705538
72Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50847721
73Ovarian steroidogenesis_Homo sapiens_hsa049130.50573772
74Pyruvate metabolism_Homo sapiens_hsa006200.50168848
75Insulin secretion_Homo sapiens_hsa049110.50061055
76beta-Alanine metabolism_Homo sapiens_hsa004100.49430592
77DNA replication_Homo sapiens_hsa030300.48770716
78Spliceosome_Homo sapiens_hsa030400.48679844
79Notch signaling pathway_Homo sapiens_hsa043300.47703116
80Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46012486
81Carbohydrate digestion and absorption_Homo sapiens_hsa049730.45581030
82Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45172771
83Folate biosynthesis_Homo sapiens_hsa007900.44846906
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44773547
85Pentose and glucuronate interconversions_Homo sapiens_hsa000400.40848540
86Mismatch repair_Homo sapiens_hsa034300.40366356
87Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.39997199
88Tyrosine metabolism_Homo sapiens_hsa003500.39939371
89Starch and sucrose metabolism_Homo sapiens_hsa005000.34662569
90Fatty acid elongation_Homo sapiens_hsa000620.34661710
91Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.33611153
92Glutamatergic synapse_Homo sapiens_hsa047240.32824432
93Hippo signaling pathway_Homo sapiens_hsa043900.32445956
94Serotonergic synapse_Homo sapiens_hsa047260.31713578
95Collecting duct acid secretion_Homo sapiens_hsa049660.30007260
96Dopaminergic synapse_Homo sapiens_hsa047280.28463057
97Fatty acid metabolism_Homo sapiens_hsa012120.26378799
98Primary immunodeficiency_Homo sapiens_hsa053400.25516895
99Mineral absorption_Homo sapiens_hsa049780.24446001
100p53 signaling pathway_Homo sapiens_hsa041150.23922191

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