

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ATP synthesis coupled proton transport (GO:0015986) | 4.97146885 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.97146885 |
| 3 | DNA deamination (GO:0045006) | 4.80334777 |
| 4 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.75281938 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.70009686 |
| 6 | viral transcription (GO:0019083) | 4.53445338 |
| 7 | regulation of memory T cell differentiation (GO:0043380) | 4.47463833 |
| 8 | ribosomal small subunit assembly (GO:0000028) | 4.43695495 |
| 9 | translational termination (GO:0006415) | 4.39890385 |
| 10 | behavioral response to nicotine (GO:0035095) | 4.38319124 |
| 11 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.10160105 |
| 12 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.09430583 |
| 13 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 4.05650607 |
| 14 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 4.04746885 |
| 15 | chaperone-mediated protein transport (GO:0072321) | 4.04255953 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.03331010 |
| 17 | cotranslational protein targeting to membrane (GO:0006613) | 4.02068812 |
| 18 | protein targeting to ER (GO:0045047) | 4.00518483 |
| 19 | positive regulation of defense response to virus by host (GO:0002230) | 3.97681126 |
| 20 | L-fucose metabolic process (GO:0042354) | 3.89093396 |
| 21 | L-fucose catabolic process (GO:0042355) | 3.89093396 |
| 22 | fucose catabolic process (GO:0019317) | 3.89093396 |
| 23 | translational elongation (GO:0006414) | 3.85456838 |
| 24 | ribosomal small subunit biogenesis (GO:0042274) | 3.80620762 |
| 25 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.79338870 |
| 26 | protein localization to endoplasmic reticulum (GO:0070972) | 3.78625913 |
| 27 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.78540858 |
| 28 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.77873241 |
| 29 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.67424391 |
| 30 | maturation of SSU-rRNA (GO:0030490) | 3.66534603 |
| 31 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.65351147 |
| 32 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.63204352 |
| 33 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.63204352 |
| 34 | protein neddylation (GO:0045116) | 3.62480802 |
| 35 | electron transport chain (GO:0022900) | 3.58773877 |
| 36 | protein complex biogenesis (GO:0070271) | 3.58384531 |
| 37 | positive regulation of interleukin-17 production (GO:0032740) | 3.53616310 |
| 38 | respiratory electron transport chain (GO:0022904) | 3.52049580 |
| 39 | positive regulation of T-helper 1 type immune response (GO:0002827) | 3.48947643 |
| 40 | regulation of activation of Janus kinase activity (GO:0010533) | 3.31533238 |
| 41 | positive regulation of prostaglandin secretion (GO:0032308) | 3.27365670 |
| 42 | ribosomal large subunit biogenesis (GO:0042273) | 3.24938177 |
| 43 | viral life cycle (GO:0019058) | 3.24559779 |
| 44 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.23532052 |
| 45 | protein-cofactor linkage (GO:0018065) | 3.23519585 |
| 46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.23302264 |
| 47 | cellular protein complex disassembly (GO:0043624) | 3.18412008 |
| 48 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.17316813 |
| 49 | NADH dehydrogenase complex assembly (GO:0010257) | 3.17316813 |
| 50 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.17316813 |
| 51 | translation (GO:0006412) | 3.16216066 |
| 52 | translational initiation (GO:0006413) | 3.14841054 |
| 53 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.07815851 |
| 54 | positive regulation of cell fate commitment (GO:0010455) | 3.07755973 |
| 55 | DNA double-strand break processing (GO:0000729) | 3.07155853 |
| 56 | base-excision repair, AP site formation (GO:0006285) | 3.06464607 |
| 57 | proteasome assembly (GO:0043248) | 3.05657331 |
| 58 | termination of RNA polymerase III transcription (GO:0006386) | 3.02529984 |
| 59 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.02529984 |
| 60 | regulation of chronic inflammatory response (GO:0002676) | 3.00543024 |
| 61 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.96363730 |
| 62 | ATP biosynthetic process (GO:0006754) | 2.96256047 |
| 63 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.92342338 |
| 64 | response to pheromone (GO:0019236) | 2.88252547 |
| 65 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.87100073 |
| 66 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.87036488 |
| 67 | respiratory chain complex IV assembly (GO:0008535) | 2.83720075 |
| 68 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.82222942 |
| 69 | pseudouridine synthesis (GO:0001522) | 2.81223219 |
| 70 | rRNA processing (GO:0006364) | 2.81049482 |
| 71 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.79122270 |
| 72 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.77467438 |
| 73 | rRNA metabolic process (GO:0016072) | 2.76955275 |
| 74 | piRNA metabolic process (GO:0034587) | 2.75069339 |
| 75 | cytochrome complex assembly (GO:0017004) | 2.74341670 |
| 76 | positive regulation of fatty acid transport (GO:2000193) | 2.73288563 |
| 77 | male meiosis I (GO:0007141) | 2.72733552 |
| 78 | cellular component biogenesis (GO:0044085) | 2.72025235 |
| 79 | positive regulation of activated T cell proliferation (GO:0042104) | 2.68648313 |
| 80 | regulation of immunoglobulin secretion (GO:0051023) | 2.68108111 |
| 81 | proton transport (GO:0015992) | 2.67106479 |
| 82 | regulation of T-helper 1 type immune response (GO:0002825) | 2.66632376 |
| 83 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.66535967 |
| 84 | hydrogen ion transmembrane transport (GO:1902600) | 2.64409339 |
| 85 | intracellular protein transmembrane import (GO:0044743) | 2.63928245 |
| 86 | positive regulation of icosanoid secretion (GO:0032305) | 2.61851094 |
| 87 | hydrogen transport (GO:0006818) | 2.61831667 |
| 88 | GPI anchor metabolic process (GO:0006505) | 2.60355129 |
| 89 | response to xenobiotic stimulus (GO:0009410) | 2.58566410 |
| 90 | protein complex disassembly (GO:0043241) | 2.57990748 |
| 91 | GTP biosynthetic process (GO:0006183) | 2.57841217 |
| 92 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.57002462 |
| 93 | negative regulation of interleukin-10 production (GO:0032693) | 2.56646372 |
| 94 | cullin deneddylation (GO:0010388) | 2.56602214 |
| 95 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 2.54796685 |
| 96 | protein targeting to membrane (GO:0006612) | 2.54780513 |
| 97 | GPI anchor biosynthetic process (GO:0006506) | 2.54600375 |
| 98 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.53602507 |
| 99 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.52545891 |
| 100 | tRNA processing (GO:0008033) | 2.52346748 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.94773898 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.67612815 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.53912821 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.38281579 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.02504034 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.95829576 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.72166976 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.61632276 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.59641336 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.54056916 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.44194529 |
| 12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.36417495 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.24093009 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.22086143 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.98734268 |
| 16 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.92753134 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.91868647 |
| 18 | EWS_26573619_Chip-Seq_HEK293_Human | 1.90542289 |
| 19 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.87735493 |
| 20 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.87722230 |
| 21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.83927478 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.78230282 |
| 23 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.77324913 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.77029795 |
| 25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.76984464 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.76690238 |
| 27 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.69077296 |
| 28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.66109303 |
| 29 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.65585491 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.61815674 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.58041642 |
| 32 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.56373791 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.49100436 |
| 34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.41952716 |
| 35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.41189690 |
| 36 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.39060076 |
| 37 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.39060076 |
| 38 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.37746399 |
| 39 | AR_20517297_ChIP-Seq_VCAP_Human | 1.37283567 |
| 40 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.35944466 |
| 41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.35777119 |
| 42 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.35511783 |
| 43 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.32621837 |
| 44 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.32215103 |
| 45 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.32215103 |
| 46 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.32202818 |
| 47 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.31861306 |
| 48 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.29540488 |
| 49 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27226742 |
| 50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.25357785 |
| 51 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.25162241 |
| 52 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.25093918 |
| 53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.24799429 |
| 54 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.23824173 |
| 55 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.22573520 |
| 56 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.21194806 |
| 57 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20407288 |
| 58 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.19189954 |
| 59 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.17916906 |
| 60 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.17525750 |
| 61 | P300_19829295_ChIP-Seq_ESCs_Human | 1.17003296 |
| 62 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.16890478 |
| 63 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.16550088 |
| 64 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.15841093 |
| 65 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15064672 |
| 66 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.14276073 |
| 67 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.14079492 |
| 68 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.11976381 |
| 69 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10935490 |
| 70 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.09499689 |
| 71 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.09422807 |
| 72 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.08813976 |
| 73 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.08376731 |
| 74 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07887365 |
| 75 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.07801189 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06751605 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06751605 |
| 78 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.06209391 |
| 79 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.01880659 |
| 80 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.01508714 |
| 81 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.01472228 |
| 82 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01053747 |
| 83 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.99868825 |
| 84 | ERA_21632823_ChIP-Seq_H3396_Human | 0.99811840 |
| 85 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.99765466 |
| 86 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.99087153 |
| 87 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98203688 |
| 88 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.98083376 |
| 89 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98010685 |
| 90 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.96784910 |
| 91 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.96454234 |
| 92 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.96058805 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96048661 |
| 94 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.95170579 |
| 95 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.93651510 |
| 96 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.92882471 |
| 97 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.92175284 |
| 98 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91355443 |
| 99 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.91226504 |
| 100 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.89743333 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.30273122 |
| 2 | MP0005671_abnormal_response_to | 2.93324969 |
| 3 | MP0008877_abnormal_DNA_methylation | 2.86653656 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 2.83336433 |
| 5 | MP0003646_muscle_fatigue | 2.59437544 |
| 6 | MP0009379_abnormal_foot_pigmentation | 2.30003833 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.25841491 |
| 8 | MP0004885_abnormal_endolymph | 2.21703037 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.21013231 |
| 10 | MP0002102_abnormal_ear_morphology | 2.19400862 |
| 11 | MP0001984_abnormal_olfaction | 2.19313672 |
| 12 | MP0008872_abnormal_physiological_respon | 2.05931646 |
| 13 | MP0009785_altered_susceptibility_to | 2.00015247 |
| 14 | MP0000685_abnormal_immune_system | 1.95756358 |
| 15 | MP0002876_abnormal_thyroid_physiology | 1.93034616 |
| 16 | MP0005646_abnormal_pituitary_gland | 1.88819111 |
| 17 | MP0002837_dystrophic_cardiac_calcinosis | 1.85818330 |
| 18 | MP0008789_abnormal_olfactory_epithelium | 1.75519647 |
| 19 | MP0004147_increased_porphyrin_level | 1.74107544 |
| 20 | MP0001790_abnormal_immune_system | 1.73980201 |
| 21 | MP0005387_immune_system_phenotype | 1.73980201 |
| 22 | MP0003011_delayed_dark_adaptation | 1.73250125 |
| 23 | MP0004142_abnormal_muscle_tone | 1.72098471 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.70236395 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 1.69610147 |
| 26 | MP0003195_calcinosis | 1.69574007 |
| 27 | MP0001968_abnormal_touch/_nociception | 1.67680163 |
| 28 | MP0001986_abnormal_taste_sensitivity | 1.66667835 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.65415293 |
| 30 | MP0002163_abnormal_gland_morphology | 1.62555282 |
| 31 | MP0005389_reproductive_system_phenotype | 1.59791022 |
| 32 | MP0001800_abnormal_humoral_immune | 1.59753572 |
| 33 | MP0003787_abnormal_imprinting | 1.58678921 |
| 34 | MP0002736_abnormal_nociception_after | 1.58427783 |
| 35 | MP0009764_decreased_sensitivity_to | 1.47986057 |
| 36 | MP0001919_abnormal_reproductive_system | 1.43308148 |
| 37 | MP0002160_abnormal_reproductive_system | 1.41701839 |
| 38 | MP0005084_abnormal_gallbladder_morpholo | 1.41037272 |
| 39 | MP0005000_abnormal_immune_tolerance | 1.40006203 |
| 40 | MP0002272_abnormal_nervous_system | 1.39376352 |
| 41 | MP0001501_abnormal_sleep_pattern | 1.35036502 |
| 42 | MP0004145_abnormal_muscle_electrophysio | 1.31587801 |
| 43 | MP0000372_irregular_coat_pigmentation | 1.29502522 |
| 44 | MP0006276_abnormal_autonomic_nervous | 1.28239579 |
| 45 | MP0003878_abnormal_ear_physiology | 1.28051953 |
| 46 | MP0005377_hearing/vestibular/ear_phenot | 1.28051953 |
| 47 | MP0008995_early_reproductive_senescence | 1.24585902 |
| 48 | MP0005085_abnormal_gallbladder_physiolo | 1.22224782 |
| 49 | MP0002723_abnormal_immune_serum | 1.20923938 |
| 50 | MP0003252_abnormal_bile_duct | 1.20482699 |
| 51 | MP0005253_abnormal_eye_physiology | 1.18241189 |
| 52 | MP0005394_taste/olfaction_phenotype | 1.17835934 |
| 53 | MP0005499_abnormal_olfactory_system | 1.17835934 |
| 54 | MP0009745_abnormal_behavioral_response | 1.17110658 |
| 55 | MP0002277_abnormal_respiratory_mucosa | 1.15617537 |
| 56 | MP0003436_decreased_susceptibility_to | 1.14667133 |
| 57 | MP0003724_increased_susceptibility_to | 1.14175171 |
| 58 | MP0009046_muscle_twitch | 1.11149241 |
| 59 | MP0002095_abnormal_skin_pigmentation | 1.09629832 |
| 60 | MP0010386_abnormal_urinary_bladder | 1.09532005 |
| 61 | MP0005410_abnormal_fertilization | 1.08917030 |
| 62 | MP0003866_abnormal_defecation | 1.07992398 |
| 63 | MP0009765_abnormal_xenobiotic_induced | 1.07129854 |
| 64 | MP0000631_abnormal_neuroendocrine_gland | 1.06822989 |
| 65 | MP0003806_abnormal_nucleotide_metabolis | 1.06754599 |
| 66 | MP0003186_abnormal_redox_activity | 1.05438353 |
| 67 | MP0006036_abnormal_mitochondrial_physio | 1.04230371 |
| 68 | MP0002452_abnormal_antigen_presenting | 1.03033921 |
| 69 | MP0001905_abnormal_dopamine_level | 1.02837485 |
| 70 | MP0003786_premature_aging | 1.01826863 |
| 71 | MP0005075_abnormal_melanosome_morpholog | 0.99095082 |
| 72 | MP0002420_abnormal_adaptive_immunity | 0.98856424 |
| 73 | MP0001873_stomach_inflammation | 0.98575106 |
| 74 | MP0005360_urolithiasis | 0.98254421 |
| 75 | MP0001819_abnormal_immune_cell | 0.97357034 |
| 76 | MP0001970_abnormal_pain_threshold | 0.96353661 |
| 77 | MP0005636_abnormal_mineral_homeostasis | 0.95451918 |
| 78 | MP0005379_endocrine/exocrine_gland_phen | 0.95274221 |
| 79 | MP0001502_abnormal_circadian_rhythm | 0.93508976 |
| 80 | MP0002138_abnormal_hepatobiliary_system | 0.93351585 |
| 81 | MP0002234_abnormal_pharynx_morphology | 0.91481382 |
| 82 | MP0004742_abnormal_vestibular_system | 0.88371685 |
| 83 | MP0008058_abnormal_DNA_repair | 0.88005834 |
| 84 | MP0001764_abnormal_homeostasis | 0.86716908 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.84396048 |
| 86 | MP0001529_abnormal_vocalization | 0.84229809 |
| 87 | MP0010155_abnormal_intestine_physiology | 0.83275956 |
| 88 | MP0000230_abnormal_systemic_arterial | 0.82918580 |
| 89 | MP0001845_abnormal_inflammatory_respons | 0.80274639 |
| 90 | MP0009333_abnormal_splenocyte_physiolog | 0.77780863 |
| 91 | MP0003137_abnormal_impulse_conducting | 0.77779021 |
| 92 | MP0001963_abnormal_hearing_physiology | 0.77367663 |
| 93 | MP0003763_abnormal_thymus_physiology | 0.76976827 |
| 94 | MP0004043_abnormal_pH_regulation | 0.76392935 |
| 95 | MP0005025_abnormal_response_to | 0.76193148 |
| 96 | MP0005423_abnormal_somatic_nervous | 0.75778373 |
| 97 | MP0001485_abnormal_pinna_reflex | 0.75154408 |
| 98 | MP0002210_abnormal_sex_determination | 0.74897525 |
| 99 | MP0003718_maternal_effect | 0.74837944 |
| 100 | MP0001348_abnormal_lacrimal_gland | 0.74682612 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.46257096 |
| 2 | Mitochondrial inheritance (HP:0001427) | 3.92994489 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.87222769 |
| 4 | Acute encephalopathy (HP:0006846) | 3.81425267 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.78086466 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.74215156 |
| 7 | IgG deficiency (HP:0004315) | 3.70479060 |
| 8 | Increased CSF lactate (HP:0002490) | 3.66138610 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.54243351 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.29393873 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.22547445 |
| 12 | Pancreatic cysts (HP:0001737) | 3.20964811 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.16371339 |
| 14 | Abnormality of midbrain morphology (HP:0002418) | 3.16371339 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.00306289 |
| 16 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.98721679 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.98721679 |
| 18 | Reticulocytopenia (HP:0001896) | 2.92979340 |
| 19 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.91809107 |
| 20 | Stomatitis (HP:0010280) | 2.85991055 |
| 21 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.82935405 |
| 22 | Cerebral edema (HP:0002181) | 2.79959457 |
| 23 | Abnormal number of erythroid precursors (HP:0012131) | 2.76592776 |
| 24 | Congenital, generalized hypertrichosis (HP:0004540) | 2.75747056 |
| 25 | Hepatic necrosis (HP:0002605) | 2.75404269 |
| 26 | Abnormality of alanine metabolism (HP:0010916) | 2.73870699 |
| 27 | Hyperalaninemia (HP:0003348) | 2.73870699 |
| 28 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.73870699 |
| 29 | Pancreatic fibrosis (HP:0100732) | 2.65931903 |
| 30 | Renal Fanconi syndrome (HP:0001994) | 2.62396218 |
| 31 | Macrocytic anemia (HP:0001972) | 2.59001629 |
| 32 | Nephronophthisis (HP:0000090) | 2.58718542 |
| 33 | Absent thumb (HP:0009777) | 2.55932496 |
| 34 | Abnormality of the renal cortex (HP:0011035) | 2.52920536 |
| 35 | Increased intramyocellular lipid droplets (HP:0012240) | 2.51574917 |
| 36 | Abolished electroretinogram (ERG) (HP:0000550) | 2.50762640 |
| 37 | Optic disc pallor (HP:0000543) | 2.50224697 |
| 38 | Exertional dyspnea (HP:0002875) | 2.46624318 |
| 39 | Increased muscle lipid content (HP:0009058) | 2.42631841 |
| 40 | Increased serum lactate (HP:0002151) | 2.40562353 |
| 41 | Methylmalonic acidemia (HP:0002912) | 2.38986216 |
| 42 | Lactic acidosis (HP:0003128) | 2.37527927 |
| 43 | Parakeratosis (HP:0001036) | 2.35442921 |
| 44 | Adrenal hypoplasia (HP:0000835) | 2.35359529 |
| 45 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.34260291 |
| 46 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.31716935 |
| 47 | True hermaphroditism (HP:0010459) | 2.28954784 |
| 48 | Abnormality of the renal medulla (HP:0100957) | 2.26265222 |
| 49 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.24564910 |
| 50 | Methylmalonic aciduria (HP:0012120) | 2.21132316 |
| 51 | Pallor (HP:0000980) | 2.20513965 |
| 52 | Medial flaring of the eyebrow (HP:0010747) | 2.19405850 |
| 53 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.16109631 |
| 54 | Colon cancer (HP:0003003) | 2.11474360 |
| 55 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.10122093 |
| 56 | Respiratory failure (HP:0002878) | 2.08925864 |
| 57 | Leukodystrophy (HP:0002415) | 2.03300638 |
| 58 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.02938692 |
| 59 | Type 2 muscle fiber atrophy (HP:0003554) | 2.02662861 |
| 60 | Hypoproteinemia (HP:0003075) | 2.00240391 |
| 61 | Type II lissencephaly (HP:0007260) | 1.98756562 |
| 62 | Polydipsia (HP:0001959) | 1.98451642 |
| 63 | Abnormal drinking behavior (HP:0030082) | 1.98451642 |
| 64 | Lethargy (HP:0001254) | 1.98118486 |
| 65 | Hypoplasia of the uterus (HP:0000013) | 1.97076789 |
| 66 | Pendular nystagmus (HP:0012043) | 1.95659965 |
| 67 | Attenuation of retinal blood vessels (HP:0007843) | 1.94616600 |
| 68 | Erythroderma (HP:0001019) | 1.93674253 |
| 69 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.93613465 |
| 70 | Abnormality of urine glucose concentration (HP:0011016) | 1.93088246 |
| 71 | Glycosuria (HP:0003076) | 1.93088246 |
| 72 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.91891436 |
| 73 | Abnormality of the ileum (HP:0001549) | 1.89629147 |
| 74 | Severe combined immunodeficiency (HP:0004430) | 1.88654618 |
| 75 | Decreased subcutaneous fat (HP:0001002) | 1.84897468 |
| 76 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.84802566 |
| 77 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.84267713 |
| 78 | Abnormality of T cells (HP:0002843) | 1.83602894 |
| 79 | Hyperglycinemia (HP:0002154) | 1.83270825 |
| 80 | Renal cortical cysts (HP:0000803) | 1.80882168 |
| 81 | Testicular atrophy (HP:0000029) | 1.80752905 |
| 82 | Polyuria (HP:0000103) | 1.78747989 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.77402386 |
| 84 | Thyroiditis (HP:0100646) | 1.77173693 |
| 85 | Fragile nails (HP:0001808) | 1.75723830 |
| 86 | Sclerocornea (HP:0000647) | 1.75672899 |
| 87 | Large for gestational age (HP:0001520) | 1.75197373 |
| 88 | Exercise intolerance (HP:0003546) | 1.75110011 |
| 89 | Asplenia (HP:0001746) | 1.73324105 |
| 90 | Meckel diverticulum (HP:0002245) | 1.71460202 |
| 91 | Brittle hair (HP:0002299) | 1.70185922 |
| 92 | Tubular atrophy (HP:0000092) | 1.68643234 |
| 93 | Retrobulbar optic neuritis (HP:0100654) | 1.67813622 |
| 94 | Optic neuritis (HP:0100653) | 1.67813622 |
| 95 | Abnormality of serum amino acid levels (HP:0003112) | 1.67143350 |
| 96 | Decreased central vision (HP:0007663) | 1.66876060 |
| 97 | Respiratory difficulties (HP:0002880) | 1.66709541 |
| 98 | Abnormality of T cell physiology (HP:0011840) | 1.65491961 |
| 99 | Cerebral hypomyelination (HP:0006808) | 1.64939842 |
| 100 | Thyroid-stimulating hormone excess (HP:0002925) | 1.62571324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.88304166 |
| 2 | ADRBK2 | 3.38479813 |
| 3 | TXK | 3.01806389 |
| 4 | TLK1 | 2.93718667 |
| 5 | FRK | 2.68586585 |
| 6 | ZAK | 2.58593476 |
| 7 | GRK1 | 2.46424797 |
| 8 | NUAK1 | 2.33807791 |
| 9 | TAOK3 | 2.32251346 |
| 10 | BCKDK | 2.31627935 |
| 11 | WNK4 | 2.23857793 |
| 12 | TIE1 | 2.00226710 |
| 13 | TRIM28 | 1.94848281 |
| 14 | CDK19 | 1.93402836 |
| 15 | VRK2 | 1.89519561 |
| 16 | STK16 | 1.84343577 |
| 17 | WNK3 | 1.77236813 |
| 18 | PINK1 | 1.59645749 |
| 19 | FES | 1.55728114 |
| 20 | INSRR | 1.47306436 |
| 21 | ITK | 1.43200339 |
| 22 | TESK2 | 1.42791089 |
| 23 | MAP3K12 | 1.42625185 |
| 24 | TEC | 1.35487912 |
| 25 | MAP2K6 | 1.33455995 |
| 26 | DYRK2 | 1.31342017 |
| 27 | OXSR1 | 1.30489346 |
| 28 | NEK1 | 1.27654858 |
| 29 | EIF2AK3 | 1.20921918 |
| 30 | ADRBK1 | 1.20297049 |
| 31 | MAPKAPK3 | 1.19412605 |
| 32 | MAP3K4 | 1.15542746 |
| 33 | KIT | 1.05436398 |
| 34 | IKBKB | 1.04812762 |
| 35 | VRK1 | 1.03313293 |
| 36 | CSNK1G3 | 1.01794000 |
| 37 | STK39 | 1.01011692 |
| 38 | BMPR1B | 1.00370352 |
| 39 | KDR | 0.94139396 |
| 40 | CSNK1G2 | 0.91819891 |
| 41 | TSSK6 | 0.91239149 |
| 42 | MYLK | 0.91219062 |
| 43 | MAPK13 | 0.87773555 |
| 44 | PASK | 0.87145900 |
| 45 | CAMKK2 | 0.86297216 |
| 46 | MAP2K7 | 0.85097478 |
| 47 | IKBKE | 0.83879775 |
| 48 | GRK6 | 0.81651757 |
| 49 | RPS6KA5 | 0.80304295 |
| 50 | CSNK1G1 | 0.79921644 |
| 51 | NME1 | 0.79728081 |
| 52 | MAP2K2 | 0.77704534 |
| 53 | SRPK1 | 0.76265766 |
| 54 | PLK3 | 0.75707309 |
| 55 | CSNK1A1L | 0.74527952 |
| 56 | MST4 | 0.71622430 |
| 57 | MUSK | 0.69458700 |
| 58 | PHKG2 | 0.69026861 |
| 59 | PHKG1 | 0.69026861 |
| 60 | STK11 | 0.68309470 |
| 61 | GRK7 | 0.67029133 |
| 62 | PRKCG | 0.66831579 |
| 63 | SYK | 0.64260511 |
| 64 | MAP4K1 | 0.64207192 |
| 65 | DAPK1 | 0.63921032 |
| 66 | JAK3 | 0.63223757 |
| 67 | EIF2AK2 | 0.62849336 |
| 68 | GRK5 | 0.62335719 |
| 69 | MAPKAPK5 | 0.62108150 |
| 70 | BCR | 0.61936865 |
| 71 | PIK3CG | 0.60265200 |
| 72 | OBSCN | 0.58615569 |
| 73 | PIK3CA | 0.58414707 |
| 74 | PRKCQ | 0.57254471 |
| 75 | BUB1 | 0.56856248 |
| 76 | PRKCE | 0.56769829 |
| 77 | PLK4 | 0.54229804 |
| 78 | MKNK1 | 0.52797838 |
| 79 | LYN | 0.51343768 |
| 80 | PDK2 | 0.49997806 |
| 81 | PRKCA | 0.49547457 |
| 82 | CSNK1A1 | 0.47184201 |
| 83 | CSNK2A2 | 0.46644785 |
| 84 | PRKACA | 0.46633786 |
| 85 | CSNK2A1 | 0.46479648 |
| 86 | BTK | 0.44579853 |
| 87 | DAPK2 | 0.43731822 |
| 88 | BMPR2 | 0.43327358 |
| 89 | IGF1R | 0.40314061 |
| 90 | TAF1 | 0.40291162 |
| 91 | LCK | 0.39853400 |
| 92 | ERBB3 | 0.39295656 |
| 93 | CAMK2A | 0.38593914 |
| 94 | AURKB | 0.37689604 |
| 95 | PRKCD | 0.37538635 |
| 96 | CAMK2D | 0.37386883 |
| 97 | TNK2 | 0.37162739 |
| 98 | PRKCI | 0.36949711 |
| 99 | CHUK | 0.36231425 |
| 100 | MKNK2 | 0.35169354 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.98289657 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.49428522 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.12120789 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.05905560 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.78309852 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.63697024 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.61163971 |
| 8 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.54757869 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.40625994 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.24187537 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.19152492 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.16484503 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 2.07071080 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.87798176 |
| 15 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.80693815 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.73459535 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.71173391 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.68759773 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.61066441 |
| 20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.59941479 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.57862186 |
| 22 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.54002906 |
| 23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.50557816 |
| 24 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.50458849 |
| 25 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.46200493 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.46172848 |
| 27 | Homologous recombination_Homo sapiens_hsa03440 | 1.46021803 |
| 28 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.41828588 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.32713596 |
| 30 | Mismatch repair_Homo sapiens_hsa03430 | 1.31569560 |
| 31 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.31459489 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.30784983 |
| 33 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.23604212 |
| 34 | RNA degradation_Homo sapiens_hsa03018 | 1.20952429 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.20816982 |
| 36 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.19417506 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.18921269 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.17748495 |
| 39 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.14128260 |
| 40 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.13823207 |
| 41 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.11464023 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.99857120 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.98457875 |
| 44 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.97626354 |
| 45 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.97189784 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 0.96232558 |
| 47 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.94117153 |
| 48 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.91217454 |
| 49 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.90713025 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 0.90365701 |
| 51 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.89716714 |
| 52 | DNA replication_Homo sapiens_hsa03030 | 0.89017699 |
| 53 | Spliceosome_Homo sapiens_hsa03040 | 0.83729082 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.80897934 |
| 55 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.80597708 |
| 56 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.78943400 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.77861704 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.77399787 |
| 59 | Base excision repair_Homo sapiens_hsa03410 | 0.74041975 |
| 60 | RNA transport_Homo sapiens_hsa03013 | 0.72664807 |
| 61 | Nicotine addiction_Homo sapiens_hsa05033 | 0.69058840 |
| 62 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67662947 |
| 63 | Retinol metabolism_Homo sapiens_hsa00830 | 0.67566937 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.64042823 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63023675 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.62649237 |
| 67 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.62194363 |
| 68 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.61393930 |
| 69 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.61355872 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.60722094 |
| 71 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.60701700 |
| 72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59396257 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58481298 |
| 74 | Morphine addiction_Homo sapiens_hsa05032 | 0.57628556 |
| 75 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.57503066 |
| 76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57056439 |
| 77 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.56580541 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55226254 |
| 79 | Viral myocarditis_Homo sapiens_hsa05416 | 0.54348027 |
| 80 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.52029139 |
| 81 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.50451466 |
| 82 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.50107720 |
| 83 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48262171 |
| 84 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.48128323 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48068710 |
| 86 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.47198815 |
| 87 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46361615 |
| 88 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.42368075 |
| 89 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.42239823 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.39665652 |
| 91 | Leishmaniasis_Homo sapiens_hsa05140 | 0.38193033 |
| 92 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37244321 |
| 93 | ABC transporters_Homo sapiens_hsa02010 | 0.36314168 |
| 94 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.34323669 |
| 95 | GABAergic synapse_Homo sapiens_hsa04727 | 0.32297745 |
| 96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.31634949 |
| 97 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.29408561 |
| 98 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.26853833 |
| 99 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.26586059 |
| 100 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.24009615 |

