

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 9.06459113 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 8.48602027 |
| 3 | viral transcription (GO:0019083) | 8.21674991 |
| 4 | translational termination (GO:0006415) | 7.83440501 |
| 5 | translational elongation (GO:0006414) | 6.51900375 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 6.49428428 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.43679515 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 6.39244372 |
| 9 | protein targeting to ER (GO:0045047) | 6.36822242 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.14499845 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 5.96273024 |
| 12 | cellular protein complex disassembly (GO:0043624) | 5.91836472 |
| 13 | viral life cycle (GO:0019058) | 5.90337343 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.74955265 |
| 15 | behavioral response to nicotine (GO:0035095) | 5.56803239 |
| 16 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 5.15782057 |
| 17 | substrate-independent telencephalic tangential migration (GO:0021826) | 5.15782057 |
| 18 | protein complex disassembly (GO:0043241) | 5.15184838 |
| 19 | macromolecular complex disassembly (GO:0032984) | 4.93211533 |
| 20 | translational initiation (GO:0006413) | 4.84190610 |
| 21 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.77891064 |
| 22 | somite development (GO:0061053) | 4.77854700 |
| 23 | nonmotile primary cilium assembly (GO:0035058) | 4.73873005 |
| 24 | pattern specification involved in kidney development (GO:0061004) | 4.55770913 |
| 25 | protein targeting to membrane (GO:0006612) | 4.53102547 |
| 26 | cell proliferation in forebrain (GO:0021846) | 4.45787785 |
| 27 | segment specification (GO:0007379) | 3.98384902 |
| 28 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.95939098 |
| 29 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.93864358 |
| 30 | tongue development (GO:0043586) | 3.86857572 |
| 31 | mRNA catabolic process (GO:0006402) | 3.74839062 |
| 32 | epithelial cilium movement (GO:0003351) | 3.74450148 |
| 33 | neuron fate determination (GO:0048664) | 3.66781614 |
| 34 | chaperone-mediated protein transport (GO:0072321) | 3.64895596 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 3.64217740 |
| 36 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.64217740 |
| 37 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.64217740 |
| 38 | motile cilium assembly (GO:0044458) | 3.62087196 |
| 39 | ribosomal large subunit biogenesis (GO:0042273) | 3.61138368 |
| 40 | negative regulation of granulocyte differentiation (GO:0030853) | 3.46088919 |
| 41 | translation (GO:0006412) | 3.40459843 |
| 42 | axonal fasciculation (GO:0007413) | 3.33588015 |
| 43 | protein complex biogenesis (GO:0070271) | 3.28532546 |
| 44 | RNA catabolic process (GO:0006401) | 3.26427368 |
| 45 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.25762335 |
| 46 | ATP synthesis coupled proton transport (GO:0015986) | 3.25762335 |
| 47 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.23219193 |
| 48 | establishment of protein localization to membrane (GO:0090150) | 3.17872933 |
| 49 | response to pheromone (GO:0019236) | 3.14168407 |
| 50 | cellular component biogenesis (GO:0044085) | 3.12167459 |
| 51 | negative regulation of response to food (GO:0032096) | 3.06924084 |
| 52 | negative regulation of appetite (GO:0032099) | 3.06924084 |
| 53 | piRNA metabolic process (GO:0034587) | 3.06806328 |
| 54 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.02556383 |
| 55 | body morphogenesis (GO:0010171) | 3.01185007 |
| 56 | synaptic transmission, cholinergic (GO:0007271) | 2.99906490 |
| 57 | resolution of meiotic recombination intermediates (GO:0000712) | 2.99385454 |
| 58 | protein neddylation (GO:0045116) | 2.97935356 |
| 59 | cilium movement (GO:0003341) | 2.97627612 |
| 60 | cardiovascular system development (GO:0072358) | 2.96250748 |
| 61 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.95381555 |
| 62 | regulation of cilium movement (GO:0003352) | 2.92563941 |
| 63 | auditory receptor cell differentiation (GO:0042491) | 2.88692224 |
| 64 | regulation of action potential (GO:0098900) | 2.88353752 |
| 65 | protein targeting (GO:0006605) | 2.83170410 |
| 66 | establishment of mitochondrion localization (GO:0051654) | 2.81654113 |
| 67 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.79468777 |
| 68 | protein polyglutamylation (GO:0018095) | 2.75841234 |
| 69 | embryonic body morphogenesis (GO:0010172) | 2.75834840 |
| 70 | regulation of microtubule-based movement (GO:0060632) | 2.73792563 |
| 71 | negative regulation of organelle assembly (GO:1902116) | 2.72494545 |
| 72 | spinal cord association neuron differentiation (GO:0021527) | 2.70332943 |
| 73 | DNA methylation involved in gamete generation (GO:0043046) | 2.69274605 |
| 74 | dendritic spine morphogenesis (GO:0060997) | 2.67704504 |
| 75 | replication fork processing (GO:0031297) | 2.67204363 |
| 76 | axonemal dynein complex assembly (GO:0070286) | 2.67104347 |
| 77 | mitochondrion transport along microtubule (GO:0047497) | 2.65037983 |
| 78 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 2.65037983 |
| 79 | head development (GO:0060322) | 2.64993988 |
| 80 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.63394099 |
| 81 | neuron recognition (GO:0008038) | 2.62502078 |
| 82 | positive regulation of T cell apoptotic process (GO:0070234) | 2.61987376 |
| 83 | L-serine metabolic process (GO:0006563) | 2.60394220 |
| 84 | establishment of protein localization to organelle (GO:0072594) | 2.55477896 |
| 85 | positive regulation of respiratory burst (GO:0060267) | 2.54941552 |
| 86 | dentate gyrus development (GO:0021542) | 2.54172438 |
| 87 | electron transport chain (GO:0022900) | 2.53371041 |
| 88 | protein localization to membrane (GO:0072657) | 2.52638929 |
| 89 | nephron tubule morphogenesis (GO:0072078) | 2.51682131 |
| 90 | nephron epithelium morphogenesis (GO:0072088) | 2.51682131 |
| 91 | respiratory electron transport chain (GO:0022904) | 2.51049890 |
| 92 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.49733196 |
| 93 | collecting duct development (GO:0072044) | 2.49083644 |
| 94 | central nervous system myelination (GO:0022010) | 2.48687714 |
| 95 | axon ensheathment in central nervous system (GO:0032291) | 2.48687714 |
| 96 | postsynaptic membrane organization (GO:0001941) | 2.47947520 |
| 97 | hypothalamus development (GO:0021854) | 2.47603132 |
| 98 | organelle disassembly (GO:1903008) | 2.44930573 |
| 99 | Sertoli cell development (GO:0060009) | 2.44898330 |
| 100 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.44291738 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 9.15204604 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.45484680 |
| 3 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.21060790 |
| 4 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.03502701 |
| 5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.22139804 |
| 6 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.19811186 |
| 7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.08746043 |
| 8 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.03369741 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 1.97598968 |
| 10 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.94717392 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.91231688 |
| 12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.85684271 |
| 13 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.83238988 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.81141810 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.81080923 |
| 16 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.79296277 |
| 17 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.74391540 |
| 18 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.73268850 |
| 19 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.69361260 |
| 20 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.68853561 |
| 21 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.68454589 |
| 22 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.57331271 |
| 23 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.54604636 |
| 24 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.52555720 |
| 25 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.52555720 |
| 26 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.51449844 |
| 27 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.46245335 |
| 28 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.41959784 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.41266370 |
| 30 | ERA_21632823_ChIP-Seq_H3396_Human | 1.39598239 |
| 31 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.38054537 |
| 32 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.36315374 |
| 33 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.36055059 |
| 34 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.35139359 |
| 35 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.31931546 |
| 36 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.31871403 |
| 37 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.30305709 |
| 38 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.29253662 |
| 39 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.28717238 |
| 40 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.27431365 |
| 41 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.26392386 |
| 42 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.26347940 |
| 43 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.23949352 |
| 44 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.23668894 |
| 45 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.22542064 |
| 46 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.22271857 |
| 47 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.22263057 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21912889 |
| 49 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.21707377 |
| 50 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.21675535 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.20707073 |
| 52 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.18518745 |
| 53 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.16736337 |
| 54 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16533378 |
| 55 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.14745845 |
| 56 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.14167721 |
| 57 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.13555488 |
| 58 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.11658752 |
| 59 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.11532813 |
| 60 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.09943063 |
| 61 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.09555608 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.09151286 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09117664 |
| 64 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.09093020 |
| 65 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.08700415 |
| 66 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.08076398 |
| 67 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.06162006 |
| 68 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05134291 |
| 69 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.04975421 |
| 70 | FUS_26573619_Chip-Seq_HEK293_Human | 1.04110480 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03266167 |
| 72 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.02652416 |
| 73 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.01749721 |
| 74 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.01018900 |
| 75 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.00699671 |
| 76 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00622843 |
| 77 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.00241540 |
| 78 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.97341519 |
| 79 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96833977 |
| 80 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.96833977 |
| 81 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.95708927 |
| 82 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94701078 |
| 83 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.94544501 |
| 84 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.93871968 |
| 85 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.93147899 |
| 86 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.93037579 |
| 87 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.92534778 |
| 88 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.91287108 |
| 89 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.89527005 |
| 90 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.89478391 |
| 91 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.89217798 |
| 92 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.88783764 |
| 93 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.86229546 |
| 94 | P68_20966046_ChIP-Seq_HELA_Human | 0.86016012 |
| 95 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.85771118 |
| 96 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.85573714 |
| 97 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.84424356 |
| 98 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.84070621 |
| 99 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.82628068 |
| 100 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.82361932 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.57168429 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.96802798 |
| 3 | MP0003122_maternal_imprinting | 3.61611737 |
| 4 | MP0003787_abnormal_imprinting | 3.33667768 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.66257542 |
| 6 | MP0004142_abnormal_muscle_tone | 2.58263657 |
| 7 | MP0008789_abnormal_olfactory_epithelium | 2.41853241 |
| 8 | MP0003646_muscle_fatigue | 2.36705857 |
| 9 | MP0003121_genomic_imprinting | 2.33279897 |
| 10 | MP0002653_abnormal_ependyma_morphology | 2.33052350 |
| 11 | MP0000778_abnormal_nervous_system | 2.24158591 |
| 12 | MP0002234_abnormal_pharynx_morphology | 2.20110647 |
| 13 | MP0005499_abnormal_olfactory_system | 2.19247134 |
| 14 | MP0005394_taste/olfaction_phenotype | 2.19247134 |
| 15 | MP0001293_anophthalmia | 2.03359945 |
| 16 | MP0005423_abnormal_somatic_nervous | 1.87779919 |
| 17 | MP0003136_yellow_coat_color | 1.83358758 |
| 18 | MP0006276_abnormal_autonomic_nervous | 1.79042844 |
| 19 | MP0003123_paternal_imprinting | 1.75862805 |
| 20 | MP0001485_abnormal_pinna_reflex | 1.75268522 |
| 21 | MP0001984_abnormal_olfaction | 1.74891092 |
| 22 | MP0004885_abnormal_endolymph | 1.72920294 |
| 23 | MP0005377_hearing/vestibular/ear_phenot | 1.70719496 |
| 24 | MP0003878_abnormal_ear_physiology | 1.70719496 |
| 25 | MP0000049_abnormal_middle_ear | 1.70364391 |
| 26 | MP0002102_abnormal_ear_morphology | 1.69377527 |
| 27 | MP0001968_abnormal_touch/_nociception | 1.65180606 |
| 28 | MP0010030_abnormal_orbit_morphology | 1.63729851 |
| 29 | MP0002638_abnormal_pupillary_reflex | 1.62511166 |
| 30 | MP0003879_abnormal_hair_cell | 1.60556063 |
| 31 | MP0001986_abnormal_taste_sensitivity | 1.55767240 |
| 32 | MP0002733_abnormal_thermal_nociception | 1.50894711 |
| 33 | MP0000631_abnormal_neuroendocrine_gland | 1.48562089 |
| 34 | MP0001529_abnormal_vocalization | 1.47163082 |
| 35 | MP0002163_abnormal_gland_morphology | 1.44519240 |
| 36 | MP0002837_dystrophic_cardiac_calcinosis | 1.41892407 |
| 37 | MP0002063_abnormal_learning/memory/cond | 1.38578674 |
| 38 | MP0002734_abnormal_mechanical_nocicepti | 1.37310957 |
| 39 | MP0002938_white_spotting | 1.36608002 |
| 40 | MP0001970_abnormal_pain_threshold | 1.35359305 |
| 41 | MP0004133_heterotaxia | 1.34334521 |
| 42 | MP0005084_abnormal_gallbladder_morpholo | 1.33906801 |
| 43 | MP0009053_abnormal_anal_canal | 1.33612518 |
| 44 | MP0001348_abnormal_lacrimal_gland | 1.32163006 |
| 45 | MP0002272_abnormal_nervous_system | 1.32029574 |
| 46 | MP0005551_abnormal_eye_electrophysiolog | 1.30622782 |
| 47 | MP0001440_abnormal_grooming_behavior | 1.29924236 |
| 48 | MP0002557_abnormal_social/conspecific_i | 1.28629834 |
| 49 | MP0000955_abnormal_spinal_cord | 1.26671137 |
| 50 | MP0002735_abnormal_chemical_nociception | 1.25662438 |
| 51 | MP0002572_abnormal_emotion/affect_behav | 1.24673678 |
| 52 | MP0003938_abnormal_ear_development | 1.24413838 |
| 53 | MP0003635_abnormal_synaptic_transmissio | 1.23843170 |
| 54 | MP0001486_abnormal_startle_reflex | 1.23592052 |
| 55 | MP0002184_abnormal_innervation | 1.22941680 |
| 56 | MP0004859_abnormal_synaptic_plasticity | 1.22844374 |
| 57 | MP0000026_abnormal_inner_ear | 1.22470605 |
| 58 | MP0009745_abnormal_behavioral_response | 1.22095316 |
| 59 | MP0005195_abnormal_posterior_eye | 1.19593643 |
| 60 | MP0003942_abnormal_urinary_system | 1.15696733 |
| 61 | MP0008872_abnormal_physiological_respon | 1.14481578 |
| 62 | MP0001905_abnormal_dopamine_level | 1.14172666 |
| 63 | MP0004742_abnormal_vestibular_system | 1.12985865 |
| 64 | MP0002736_abnormal_nociception_after | 1.12502743 |
| 65 | MP0005379_endocrine/exocrine_gland_phen | 1.10814715 |
| 66 | MP0003283_abnormal_digestive_organ | 1.07748542 |
| 67 | MP0002249_abnormal_larynx_morphology | 1.06424062 |
| 68 | MP0002095_abnormal_skin_pigmentation | 1.06044027 |
| 69 | MP0003880_abnormal_central_pattern | 1.06033263 |
| 70 | MP0002752_abnormal_somatic_nervous | 1.04881366 |
| 71 | MP0001963_abnormal_hearing_physiology | 1.03236117 |
| 72 | MP0003890_abnormal_embryonic-extraembry | 1.00674541 |
| 73 | MP0002233_abnormal_nose_morphology | 0.99040476 |
| 74 | MP0005645_abnormal_hypothalamus_physiol | 0.98721888 |
| 75 | MP0002152_abnormal_brain_morphology | 0.96651356 |
| 76 | MP0001286_abnormal_eye_development | 0.94638066 |
| 77 | MP0001324_abnormal_eye_pigmentation | 0.93511393 |
| 78 | MP0005389_reproductive_system_phenotype | 0.92620065 |
| 79 | MP0002138_abnormal_hepatobiliary_system | 0.91897209 |
| 80 | MP0004145_abnormal_muscle_electrophysio | 0.91731529 |
| 81 | MP0002882_abnormal_neuron_morphology | 0.90408800 |
| 82 | MP0002064_seizures | 0.89356821 |
| 83 | MP0002160_abnormal_reproductive_system | 0.89309068 |
| 84 | MP0002067_abnormal_sensory_capabilities | 0.89175598 |
| 85 | MP0003119_abnormal_digestive_system | 0.85882129 |
| 86 | MP0008875_abnormal_xenobiotic_pharmacok | 0.84273495 |
| 87 | MP0006072_abnormal_retinal_apoptosis | 0.83829972 |
| 88 | MP0003861_abnormal_nervous_system | 0.82508853 |
| 89 | MP0003937_abnormal_limbs/digits/tail_de | 0.81996555 |
| 90 | MP0009046_muscle_twitch | 0.79042446 |
| 91 | MP0003186_abnormal_redox_activity | 0.78344942 |
| 92 | MP0002822_catalepsy | 0.77247141 |
| 93 | MP0003755_abnormal_palate_morphology | 0.75169569 |
| 94 | MP0002116_abnormal_craniofacial_bone | 0.74828400 |
| 95 | MP0005646_abnormal_pituitary_gland | 0.73885078 |
| 96 | MP0005174_abnormal_tail_pigmentation | 0.73538127 |
| 97 | MP0000427_abnormal_hair_cycle | 0.73143525 |
| 98 | MP0003698_abnormal_male_reproductive | 0.72209295 |
| 99 | MP0002210_abnormal_sex_determination | 0.71853162 |
| 100 | MP0004924_abnormal_behavior | 0.71830604 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 7.78778868 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.97048329 |
| 3 | Septo-optic dysplasia (HP:0100842) | 4.67683210 |
| 4 | Molar tooth sign on MRI (HP:0002419) | 4.07218656 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 4.07218656 |
| 6 | Macrocytic anemia (HP:0001972) | 3.98734653 |
| 7 | Pancreatic fibrosis (HP:0100732) | 3.71275156 |
| 8 | Absent/shortened dynein arms (HP:0200106) | 3.40740845 |
| 9 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.40740845 |
| 10 | Abnormal hemoglobin (HP:0011902) | 3.33275420 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 3.22154316 |
| 12 | Abnormal number of erythroid precursors (HP:0012131) | 3.21367539 |
| 13 | Pancreatic cysts (HP:0001737) | 3.16008768 |
| 14 | Stenosis of the external auditory canal (HP:0000402) | 3.13780167 |
| 15 | Pallor (HP:0000980) | 3.11526418 |
| 16 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.92631448 |
| 17 | Maternal diabetes (HP:0009800) | 2.92501766 |
| 18 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.88910868 |
| 19 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.85691308 |
| 20 | Absent thumb (HP:0009777) | 2.81346064 |
| 21 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.79208319 |
| 22 | Abnormal ciliary motility (HP:0012262) | 2.78532035 |
| 23 | Acute encephalopathy (HP:0006846) | 2.77922881 |
| 24 | Abnormality of the labia minora (HP:0012880) | 2.75763883 |
| 25 | Agitation (HP:0000713) | 2.75339542 |
| 26 | Rib fusion (HP:0000902) | 2.73767966 |
| 27 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.72973913 |
| 28 | Nephronophthisis (HP:0000090) | 2.72546426 |
| 29 | Medial flaring of the eyebrow (HP:0010747) | 2.72333297 |
| 30 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.72330979 |
| 31 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.72330979 |
| 32 | Asplenia (HP:0001746) | 2.69939566 |
| 33 | Supernumerary spleens (HP:0009799) | 2.69645776 |
| 34 | Mitochondrial inheritance (HP:0001427) | 2.68850818 |
| 35 | Absent septum pellucidum (HP:0001331) | 2.68775139 |
| 36 | True hermaphroditism (HP:0010459) | 2.68513674 |
| 37 | Pendular nystagmus (HP:0012043) | 2.64392774 |
| 38 | Polyphagia (HP:0002591) | 2.62755663 |
| 39 | Optic nerve hypoplasia (HP:0000609) | 2.58127638 |
| 40 | Anencephaly (HP:0002323) | 2.57679733 |
| 41 | Cystic liver disease (HP:0006706) | 2.56895849 |
| 42 | Depressed nasal ridge (HP:0000457) | 2.53408869 |
| 43 | Colon cancer (HP:0003003) | 2.50612940 |
| 44 | Progressive macrocephaly (HP:0004481) | 2.50383652 |
| 45 | Abnormality of reticulocytes (HP:0004312) | 2.40557110 |
| 46 | Growth hormone deficiency (HP:0000824) | 2.39801931 |
| 47 | Gait imbalance (HP:0002141) | 2.36949509 |
| 48 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.32049609 |
| 49 | Increased CSF lactate (HP:0002490) | 2.29835384 |
| 50 | Lipid accumulation in hepatocytes (HP:0006561) | 2.26136081 |
| 51 | Abnormality of the renal medulla (HP:0100957) | 2.23362665 |
| 52 | Increased hepatocellular lipid droplets (HP:0006565) | 2.23302452 |
| 53 | Anophthalmia (HP:0000528) | 2.21072003 |
| 54 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.19207902 |
| 55 | Congenital stationary night blindness (HP:0007642) | 2.17750913 |
| 56 | Oligodactyly (hands) (HP:0001180) | 2.17514389 |
| 57 | Congenital primary aphakia (HP:0007707) | 2.14936762 |
| 58 | Sclerocornea (HP:0000647) | 2.10315701 |
| 59 | Tubular atrophy (HP:0000092) | 2.07166965 |
| 60 | Thyroid-stimulating hormone excess (HP:0002925) | 2.04581514 |
| 61 | Abnormality of the septum pellucidum (HP:0007375) | 2.03475521 |
| 62 | Abnormality of the diencephalon (HP:0010662) | 2.02384150 |
| 63 | Adrenal hypoplasia (HP:0000835) | 2.01840591 |
| 64 | Poor suck (HP:0002033) | 2.01502546 |
| 65 | Type II lissencephaly (HP:0007260) | 2.01217627 |
| 66 | Hip dysplasia (HP:0001385) | 2.01051051 |
| 67 | Hyperthyroidism (HP:0000836) | 1.99477793 |
| 68 | Polydipsia (HP:0001959) | 1.99213403 |
| 69 | Abnormal drinking behavior (HP:0030082) | 1.99213403 |
| 70 | Abnormal eating behavior (HP:0100738) | 1.99106632 |
| 71 | Oligodactyly (HP:0012165) | 1.99029095 |
| 72 | Nephrogenic diabetes insipidus (HP:0009806) | 1.98243064 |
| 73 | Osteomalacia (HP:0002749) | 1.97954420 |
| 74 | Increased intramyocellular lipid droplets (HP:0012240) | 1.97337717 |
| 75 | Renal Fanconi syndrome (HP:0001994) | 1.96628456 |
| 76 | Focal motor seizures (HP:0011153) | 1.96130864 |
| 77 | Pachygyria (HP:0001302) | 1.96083867 |
| 78 | Holoprosencephaly (HP:0001360) | 1.94770674 |
| 79 | Partial duplication of thumb phalanx (HP:0009944) | 1.94372289 |
| 80 | Postaxial foot polydactyly (HP:0001830) | 1.92929371 |
| 81 | Hyperventilation (HP:0002883) | 1.92196852 |
| 82 | Chronic hepatic failure (HP:0100626) | 1.91360583 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.90991930 |
| 84 | Cerebral edema (HP:0002181) | 1.90744691 |
| 85 | Abnormal number of incisors (HP:0011064) | 1.87302159 |
| 86 | Poor coordination (HP:0002370) | 1.85191192 |
| 87 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.85049339 |
| 88 | Lissencephaly (HP:0001339) | 1.84183699 |
| 89 | Hepatocellular necrosis (HP:0001404) | 1.83179770 |
| 90 | Abnormality of DNA repair (HP:0003254) | 1.82524208 |
| 91 | Renal dysplasia (HP:0000110) | 1.81423338 |
| 92 | Myokymia (HP:0002411) | 1.81201092 |
| 93 | Optic disc pallor (HP:0000543) | 1.80637925 |
| 94 | Elfin facies (HP:0004428) | 1.80252058 |
| 95 | Flat capital femoral epiphysis (HP:0003370) | 1.79960249 |
| 96 | Triphalangeal thumb (HP:0001199) | 1.76527218 |
| 97 | Renovascular hypertension (HP:0100817) | 1.75879341 |
| 98 | Vaginal atresia (HP:0000148) | 1.75196682 |
| 99 | Hypoplasia of the ulna (HP:0003022) | 1.74709232 |
| 100 | Increased muscle lipid content (HP:0009058) | 1.73253198 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 4.29492227 |
| 2 | DYRK2 | 2.64558951 |
| 3 | STK39 | 2.62303589 |
| 4 | STK16 | 2.58632593 |
| 5 | EPHB2 | 2.55073936 |
| 6 | ADRBK2 | 2.41791884 |
| 7 | PINK1 | 2.40800573 |
| 8 | CASK | 2.33435336 |
| 9 | MAP3K9 | 2.32680774 |
| 10 | LRRK2 | 2.07763184 |
| 11 | GRK1 | 2.02634098 |
| 12 | MAP3K11 | 1.94075148 |
| 13 | CDC7 | 1.82623200 |
| 14 | TYRO3 | 1.81294395 |
| 15 | WNK1 | 1.75564230 |
| 16 | MAP3K4 | 1.73965163 |
| 17 | MAP4K2 | 1.69451312 |
| 18 | CDK19 | 1.67123239 |
| 19 | BCKDK | 1.53257417 |
| 20 | NTRK2 | 1.53143211 |
| 21 | PAK3 | 1.37363481 |
| 22 | MARK1 | 1.36763384 |
| 23 | PAK6 | 1.34641493 |
| 24 | MAPK13 | 1.33703481 |
| 25 | WNK3 | 1.31886392 |
| 26 | NUAK1 | 1.31783642 |
| 27 | TNIK | 1.28628360 |
| 28 | CAMKK2 | 1.27394806 |
| 29 | BRAF | 1.26877897 |
| 30 | PRKCG | 1.23624023 |
| 31 | CAMK1D | 1.21418870 |
| 32 | PIK3CA | 1.15408127 |
| 33 | LIMK1 | 1.13907859 |
| 34 | PHKG1 | 1.11152205 |
| 35 | PHKG2 | 1.11152205 |
| 36 | CAMK1 | 1.10916069 |
| 37 | PRKD3 | 1.06163163 |
| 38 | PLK2 | 1.06151029 |
| 39 | PRKCI | 1.03049649 |
| 40 | CAMKK1 | 1.02514438 |
| 41 | DAPK3 | 1.00836342 |
| 42 | PIM2 | 1.00342405 |
| 43 | RPS6KA2 | 0.99944124 |
| 44 | VRK2 | 0.98157910 |
| 45 | SGK494 | 0.96492203 |
| 46 | SGK223 | 0.96492203 |
| 47 | TIE1 | 0.95900514 |
| 48 | TAOK3 | 0.95182787 |
| 49 | CAMK1G | 0.94960119 |
| 50 | MAP2K7 | 0.91280059 |
| 51 | PRKCH | 0.89730970 |
| 52 | RPS6KA6 | 0.87767349 |
| 53 | STK11 | 0.86997338 |
| 54 | OXSR1 | 0.85715637 |
| 55 | ZAK | 0.82586068 |
| 56 | AURKA | 0.81068781 |
| 57 | PASK | 0.78792357 |
| 58 | MARK2 | 0.77662499 |
| 59 | MKNK2 | 0.76994185 |
| 60 | PRKCZ | 0.75841135 |
| 61 | INSRR | 0.75797399 |
| 62 | PRKCQ | 0.74279588 |
| 63 | DYRK1B | 0.73695573 |
| 64 | ADRBK1 | 0.72510085 |
| 65 | RPS6KC1 | 0.70741142 |
| 66 | RPS6KL1 | 0.70741142 |
| 67 | ARAF | 0.69573050 |
| 68 | TLK1 | 0.65327140 |
| 69 | MOS | 0.63750173 |
| 70 | CSNK1G2 | 0.62457517 |
| 71 | PRKACA | 0.61110997 |
| 72 | AURKB | 0.60791149 |
| 73 | BMPR1B | 0.60297589 |
| 74 | ABL2 | 0.59707734 |
| 75 | MAP3K12 | 0.58046203 |
| 76 | MAP2K4 | 0.57067313 |
| 77 | CAMK2A | 0.55335289 |
| 78 | FRK | 0.53661299 |
| 79 | CSNK1G3 | 0.53287073 |
| 80 | CAMK4 | 0.52799163 |
| 81 | MARK3 | 0.52188104 |
| 82 | IRAK4 | 0.51190507 |
| 83 | PRKCE | 0.50994843 |
| 84 | CSNK2A2 | 0.49358637 |
| 85 | CSNK1E | 0.49232311 |
| 86 | KSR1 | 0.48571067 |
| 87 | PNCK | 0.45254046 |
| 88 | CDK14 | 0.44988893 |
| 89 | MINK1 | 0.44720270 |
| 90 | EPHA4 | 0.43830151 |
| 91 | PLK4 | 0.43192979 |
| 92 | CSNK1G1 | 0.42781730 |
| 93 | ERBB2 | 0.42243973 |
| 94 | RPS6KA1 | 0.41778591 |
| 95 | CDK5 | 0.40918284 |
| 96 | ROCK1 | 0.40503481 |
| 97 | MAP2K2 | 0.38325633 |
| 98 | CCNB1 | 0.38026772 |
| 99 | AKT1 | 0.37331629 |
| 100 | CDK11A | 0.36618556 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.17854111 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.72581694 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.14040303 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.91837916 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.43630516 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.19762053 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.14785556 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.12890076 |
| 9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.12380136 |
| 10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.03832692 |
| 11 | Nicotine addiction_Homo sapiens_hsa05033 | 1.92861816 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.87441061 |
| 13 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.85349986 |
| 14 | Phototransduction_Homo sapiens_hsa04744 | 1.62321082 |
| 15 | RNA polymerase_Homo sapiens_hsa03020 | 1.54050887 |
| 16 | Protein export_Homo sapiens_hsa03060 | 1.50099905 |
| 17 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.45867827 |
| 18 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.44795795 |
| 19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.40884400 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.37018857 |
| 21 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.29133778 |
| 22 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.26210992 |
| 23 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.24884533 |
| 24 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.24241237 |
| 25 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.23097017 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.21286603 |
| 27 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.21055684 |
| 28 | Morphine addiction_Homo sapiens_hsa05032 | 1.20126744 |
| 29 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.19296071 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.16660108 |
| 31 | Sulfur relay system_Homo sapiens_hsa04122 | 1.12816795 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.12069329 |
| 33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.10141101 |
| 34 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.09996357 |
| 35 | Basal transcription factors_Homo sapiens_hsa03022 | 1.09794140 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.05467986 |
| 37 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.01847181 |
| 38 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.00854352 |
| 39 | Insulin secretion_Homo sapiens_hsa04911 | 0.98902696 |
| 40 | Homologous recombination_Homo sapiens_hsa03440 | 0.97965613 |
| 41 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.96969539 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.96423268 |
| 43 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.94606774 |
| 44 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.87724987 |
| 45 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.87127757 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.85952984 |
| 47 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.85062759 |
| 48 | Axon guidance_Homo sapiens_hsa04360 | 0.84336734 |
| 49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.81783427 |
| 50 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.79509863 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78743323 |
| 52 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.78485388 |
| 53 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.75120553 |
| 54 | Mismatch repair_Homo sapiens_hsa03430 | 0.73904266 |
| 55 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.71079166 |
| 56 | Taste transduction_Homo sapiens_hsa04742 | 0.70838122 |
| 57 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.69775551 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66156635 |
| 59 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.65921099 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.65824954 |
| 61 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.65375413 |
| 62 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.65326010 |
| 63 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.64912297 |
| 64 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.64479286 |
| 65 | GABAergic synapse_Homo sapiens_hsa04727 | 0.62524422 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61429995 |
| 67 | Salivary secretion_Homo sapiens_hsa04970 | 0.60361853 |
| 68 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.59989623 |
| 69 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.59980842 |
| 70 | Purine metabolism_Homo sapiens_hsa00230 | 0.58119547 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55657118 |
| 72 | Proteasome_Homo sapiens_hsa03050 | 0.54829482 |
| 73 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.54251212 |
| 74 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.53280105 |
| 75 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.52500204 |
| 76 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.49002316 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.48174816 |
| 78 | Asthma_Homo sapiens_hsa05310 | 0.47068394 |
| 79 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.46859061 |
| 80 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.46327734 |
| 81 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.46244833 |
| 82 | Circadian entrainment_Homo sapiens_hsa04713 | 0.45000006 |
| 83 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.44012741 |
| 84 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.42597581 |
| 85 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.40180063 |
| 86 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.38025027 |
| 87 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.36355867 |
| 88 | DNA replication_Homo sapiens_hsa03030 | 0.35552448 |
| 89 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.34771398 |
| 90 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.34454989 |
| 91 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.33859604 |
| 92 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.32300780 |
| 93 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.32143021 |
| 94 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.32040602 |
| 95 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.31828982 |
| 96 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30995147 |
| 97 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.30546930 |
| 98 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.28377008 |
| 99 | Bile secretion_Homo sapiens_hsa04976 | 0.27960783 |
| 100 | Melanogenesis_Homo sapiens_hsa04916 | 0.27621275 |

