RPL17P20

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.98780793
2translational termination (GO:0006415)6.62613770
3ribosomal small subunit assembly (GO:0000028)6.31669334
4ribosomal small subunit biogenesis (GO:0042274)6.09728911
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.74538812
6cotranslational protein targeting to membrane (GO:0006613)5.67090034
7translational elongation (GO:0006414)5.65766347
8protein targeting to ER (GO:0045047)5.64182203
9establishment of protein localization to endoplasmic reticulum (GO:0072599)5.42840098
10maturation of SSU-rRNA (GO:0030490)5.35100551
11protein neddylation (GO:0045116)5.34746369
12protein localization to endoplasmic reticulum (GO:0070972)5.27458847
13viral life cycle (GO:0019058)5.10356372
14cellular protein complex disassembly (GO:0043624)4.99951979
15behavioral response to nicotine (GO:0035095)4.93490719
16ribosomal large subunit biogenesis (GO:0042273)4.75881636
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.67522771
18ATP synthesis coupled proton transport (GO:0015986)4.65033430
19energy coupled proton transport, down electrochemical gradient (GO:0015985)4.65033430
20substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.48665746
21substrate-independent telencephalic tangential migration (GO:0021826)4.48665746
22RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.47050657
23tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.47050657
24mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.30744036
25translational initiation (GO:0006413)4.28688683
26protein complex disassembly (GO:0043241)4.25270361
27chaperone-mediated protein transport (GO:0072321)4.24433147
28macromolecular complex disassembly (GO:0032984)4.13931445
29mitochondrial respiratory chain complex I assembly (GO:0032981)4.03006165
30NADH dehydrogenase complex assembly (GO:0010257)4.03006165
31mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.03006165
32protein complex biogenesis (GO:0070271)3.96703278
33cell proliferation in forebrain (GO:0021846)3.92664950
34establishment of protein localization to mitochondrial membrane (GO:0090151)3.90073668
35protein targeting to membrane (GO:0006612)3.77145843
36mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.72755161
37GTP biosynthetic process (GO:0006183)3.71090746
38translation (GO:0006412)3.55797493
39cardiovascular system development (GO:0072358)3.55483957
40cellular component biogenesis (GO:0044085)3.47455306
41mitochondrial respiratory chain complex assembly (GO:0033108)3.47107171
42response to gravity (GO:0009629)3.43481327
43ribonucleoprotein complex biogenesis (GO:0022613)3.43455205
44nuclear-transcribed mRNA catabolic process (GO:0000956)3.42015709
45somite development (GO:0061053)3.31420813
46respiratory electron transport chain (GO:0022904)3.29889071
47electron transport chain (GO:0022900)3.25145699
48mRNA catabolic process (GO:0006402)3.24656639
49DNA deamination (GO:0045006)3.21611762
50nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.19630452
51negative regulation of muscle hypertrophy (GO:0014741)3.18493976
52exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.11620964
53UTP metabolic process (GO:0046051)3.10404219
54epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.07642565
55UTP biosynthetic process (GO:0006228)3.07273150
56tongue development (GO:0043586)3.07132046
57protein polyglutamylation (GO:0018095)2.99826588
58purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.94688953
59platelet dense granule organization (GO:0060155)2.92980322
60axonemal dynein complex assembly (GO:0070286)2.91452405
61purine nucleoside triphosphate biosynthetic process (GO:0009145)2.91423415
62RNA catabolic process (GO:0006401)2.90805073
63neuron fate determination (GO:0048664)2.85262852
64skeletal muscle tissue regeneration (GO:0043403)2.84925789
65pattern specification involved in kidney development (GO:0061004)2.84736297
66pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.82221309
67ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.80994149
68regulation of skeletal muscle contraction (GO:0014819)2.80815055
69intraciliary transport (GO:0042073)2.80304147
70epithelial cilium movement (GO:0003351)2.75900689
71regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.74912818
72water-soluble vitamin biosynthetic process (GO:0042364)2.74179418
73nonmotile primary cilium assembly (GO:0035058)2.73977090
74ATP biosynthetic process (GO:0006754)2.70562070
75hydrogen ion transmembrane transport (GO:1902600)2.67756934
76myoblast migration (GO:0051451)2.66265901
77ribonucleoprotein complex disassembly (GO:0032988)2.65391652
78segment specification (GO:0007379)2.63981770
79establishment of mitochondrion localization (GO:0051654)2.63269835
80organelle disassembly (GO:1903008)2.61296178
81positive regulation of T cell apoptotic process (GO:0070234)2.60123227
82sequestering of actin monomers (GO:0042989)2.57331235
83protein targeting (GO:0006605)2.55075929
84viral protein processing (GO:0019082)2.55058912
85establishment of protein localization to membrane (GO:0090150)2.52849390
86preassembly of GPI anchor in ER membrane (GO:0016254)2.51946529
87pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.51784844
88pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.50940025
89ribonucleoside triphosphate biosynthetic process (GO:0009201)2.50247674
90protein-cofactor linkage (GO:0018065)2.50095004
91dentate gyrus development (GO:0021542)2.49202353
92proton transport (GO:0015992)2.47760854
93CTP metabolic process (GO:0046036)2.46532298
94CTP biosynthetic process (GO:0006241)2.46532298
95respiratory chain complex IV assembly (GO:0008535)2.46021547
96hypothalamus development (GO:0021854)2.45258387
97regulation of cilium movement (GO:0003352)2.44736337
98pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.44287703
99behavioral response to ethanol (GO:0048149)2.44176719
100hydrogen transport (GO:0006818)2.43698812

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.33219077
2VDR_22108803_ChIP-Seq_LS180_Human3.85424691
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.60431506
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.53526124
5TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.43410516
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.61661109
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.52290943
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.43544379
9ZNF274_21170338_ChIP-Seq_K562_Hela2.41211707
10IRF1_19129219_ChIP-ChIP_H3396_Human2.36521193
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.27109318
12NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.11504949
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.10413271
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.00386721
15BMI1_23680149_ChIP-Seq_NPCS_Mouse1.97792391
16ELF1_17652178_ChIP-ChIP_JURKAT_Human1.95985061
17ETS1_20019798_ChIP-Seq_JURKAT_Human1.93677588
18JARID2_20064375_ChIP-Seq_MESCs_Mouse1.90272392
19EZH2_27304074_Chip-Seq_ESCs_Mouse1.88028456
20RBPJ_22232070_ChIP-Seq_NCS_Mouse1.82770207
21EED_16625203_ChIP-ChIP_MESCs_Mouse1.76948178
22CBX2_27304074_Chip-Seq_ESCs_Mouse1.75792012
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.73621895
24REST_21632747_ChIP-Seq_MESCs_Mouse1.68661697
25SUZ12_27294783_Chip-Seq_ESCs_Mouse1.66015174
26EZH2_27294783_Chip-Seq_ESCs_Mouse1.62540882
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.61664575
28FUS_26573619_Chip-Seq_HEK293_Human1.60002805
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.46856447
30MYC_18940864_ChIP-ChIP_HL60_Human1.45268994
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44944620
32CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.44856806
33MYC_18555785_ChIP-Seq_MESCs_Mouse1.44409283
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.44026394
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.43433026
36JARID2_20075857_ChIP-Seq_MESCs_Mouse1.42401832
37SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.41585257
38FOXP3_21729870_ChIP-Seq_TREG_Human1.40302637
39FLI1_27457419_Chip-Seq_LIVER_Mouse1.36004255
40RNF2_27304074_Chip-Seq_NSC_Mouse1.34288433
41GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.33353611
42SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.33026395
43CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.32900256
44REST_18959480_ChIP-ChIP_MESCs_Mouse1.32856682
45HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.30584545
46VDR_23849224_ChIP-Seq_CD4+_Human1.29438022
47GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.29228047
48TP53_20018659_ChIP-ChIP_R1E_Mouse1.27810174
49TTF2_22483619_ChIP-Seq_HELA_Human1.26656375
50CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.22848056
51RNF2_18974828_ChIP-Seq_MESCs_Mouse1.22396459
52EZH2_18974828_ChIP-Seq_MESCs_Mouse1.22396459
53SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.22379429
54XRN2_22483619_ChIP-Seq_HELA_Human1.21491682
55TP53_22573176_ChIP-Seq_HFKS_Human1.20756089
56MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.20459919
57POU5F1_16153702_ChIP-ChIP_HESCs_Human1.20028175
58TAF2_19829295_ChIP-Seq_ESCs_Human1.17177513
59EWS_26573619_Chip-Seq_HEK293_Human1.16893411
60GATA3_21878914_ChIP-Seq_MCF-7_Human1.16732948
61CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.15938391
62BP1_19119308_ChIP-ChIP_Hs578T_Human1.15359222
63GATA1_26923725_Chip-Seq_HPCs_Mouse1.15350267
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.14805680
65ETV2_25802403_ChIP-Seq_MESCs_Mouse1.14474223
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.14330987
67ZFP57_27257070_Chip-Seq_ESCs_Mouse1.11737407
68CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.11349728
69YY1_21170310_ChIP-Seq_MESCs_Mouse1.11196293
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.10286596
71SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.10049168
72GABP_19822575_ChIP-Seq_HepG2_Human1.09815215
73RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.09743995
74NCOR_22424771_ChIP-Seq_293T_Human1.09549788
75TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08210686
76POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.08210686
77NANOG_20526341_ChIP-Seq_ESCs_Human1.07550978
78FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06882752
79ERA_21632823_ChIP-Seq_H3396_Human1.06695539
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05687513
81CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.02949562
82SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.02467456
83PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98263261
84AR_20517297_ChIP-Seq_VCAP_Human0.97320946
85MYC_18358816_ChIP-ChIP_MESCs_Mouse0.96126114
86CREB1_15753290_ChIP-ChIP_HEK293T_Human0.95250815
87FOXH1_21741376_ChIP-Seq_EPCs_Human0.94897137
88IGF1R_20145208_ChIP-Seq_DFB_Human0.94673347
89RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.94228228
90SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93739807
91P300_19829295_ChIP-Seq_ESCs_Human0.92780729
92CBP_20019798_ChIP-Seq_JUKART_Human0.92347893
93IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.92347893
94ELK1_19687146_ChIP-ChIP_HELA_Human0.92223824
95EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.91968038
96CTBP2_25329375_ChIP-Seq_LNCAP_Human0.91748694
97FOXA1_27270436_Chip-Seq_PROSTATE_Human0.90963113
98FOXA1_25329375_ChIP-Seq_VCAP_Human0.90963113
99TOP2B_26459242_ChIP-Seq_MCF-7_Human0.89709006
100PCGF2_27294783_Chip-Seq_NPCs_Mouse0.88002416

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.22915175
2MP0006292_abnormal_olfactory_placode4.73646713
3MP0003787_abnormal_imprinting3.75800700
4MP0003123_paternal_imprinting2.93246535
5MP0003122_maternal_imprinting2.49413002
6MP0008789_abnormal_olfactory_epithelium2.47483420
7MP0003646_muscle_fatigue2.36745916
8MP0001293_anophthalmia2.12109792
9MP0008877_abnormal_DNA_methylation2.09215063
10MP0004145_abnormal_muscle_electrophysio2.08753900
11MP0002837_dystrophic_cardiac_calcinosis2.06098379
12MP0002163_abnormal_gland_morphology2.04302373
13MP0005423_abnormal_somatic_nervous2.02838069
14MP0005394_taste/olfaction_phenotype1.95855249
15MP0005499_abnormal_olfactory_system1.95855249
16MP0004142_abnormal_muscle_tone1.94057658
17MP0003121_genomic_imprinting1.90889783
18MP0004885_abnormal_endolymph1.88109380
19MP0006276_abnormal_autonomic_nervous1.85779633
20MP0002102_abnormal_ear_morphology1.80434249
21MP0005646_abnormal_pituitary_gland1.73351972
22MP0002638_abnormal_pupillary_reflex1.72171828
23MP0000631_abnormal_neuroendocrine_gland1.65381536
24MP0003880_abnormal_central_pattern1.63991514
25MP0000778_abnormal_nervous_system1.60908586
26MP0002653_abnormal_ependyma_morphology1.59533704
27MP0000049_abnormal_middle_ear1.58111154
28MP0001986_abnormal_taste_sensitivity1.57452626
29MP0002876_abnormal_thyroid_physiology1.56177972
30MP0006072_abnormal_retinal_apoptosis1.55140167
31MP0002138_abnormal_hepatobiliary_system1.54159098
32MP0004133_heterotaxia1.50150766
33MP0001968_abnormal_touch/_nociception1.42615787
34MP0002736_abnormal_nociception_after1.42080957
35MP0002272_abnormal_nervous_system1.41738541
36MP0005551_abnormal_eye_electrophysiolog1.36600177
37MP0008872_abnormal_physiological_respon1.34451371
38MP0005084_abnormal_gallbladder_morpholo1.32860204
39MP0001440_abnormal_grooming_behavior1.30432787
40MP0002938_white_spotting1.30052371
41MP0002160_abnormal_reproductive_system1.29055580
42MP0001485_abnormal_pinna_reflex1.28703413
43MP0002184_abnormal_innervation1.28675682
44MP0002822_catalepsy1.25931146
45MP0002557_abnormal_social/conspecific_i1.25761968
46MP0009745_abnormal_behavioral_response1.24745975
47MP0005195_abnormal_posterior_eye1.20118887
48MP0001905_abnormal_dopamine_level1.18001165
49MP0001529_abnormal_vocalization1.17509475
50MP0009053_abnormal_anal_canal1.16246943
51MP0000955_abnormal_spinal_cord1.16091789
52MP0001286_abnormal_eye_development1.14648757
53MP0002752_abnormal_somatic_nervous1.14314228
54MP0000026_abnormal_inner_ear1.13318372
55MP0005379_endocrine/exocrine_gland_phen1.10273663
56MP0004147_increased_porphyrin_level1.08884281
57MP0008775_abnormal_heart_ventricle1.08869365
58MP0002733_abnormal_thermal_nociception1.07752564
59MP0002095_abnormal_skin_pigmentation1.07201948
60MP0001486_abnormal_startle_reflex1.06844399
61MP0008995_early_reproductive_senescence1.06310586
62MP0005389_reproductive_system_phenotype1.05599339
63MP0005377_hearing/vestibular/ear_phenot1.03948576
64MP0003878_abnormal_ear_physiology1.03948576
65MP0010030_abnormal_orbit_morphology1.03233776
66MP0009046_muscle_twitch1.02809890
67MP0001188_hyperpigmentation1.01380279
68MP0001970_abnormal_pain_threshold0.99440801
69MP0003938_abnormal_ear_development0.98745797
70MP0002572_abnormal_emotion/affect_behav0.96107252
71MP0002233_abnormal_nose_morphology0.94914671
72MP0003937_abnormal_limbs/digits/tail_de0.94736756
73MP0003942_abnormal_urinary_system0.91776224
74MP0003186_abnormal_redox_activity0.90598095
75MP0005645_abnormal_hypothalamus_physiol0.90554714
76MP0002063_abnormal_learning/memory/cond0.90465063
77MP0000372_irregular_coat_pigmentation0.90147879
78MP0001963_abnormal_hearing_physiology0.88285239
79MP0002735_abnormal_chemical_nociception0.87296604
80MP0003635_abnormal_synaptic_transmissio0.86460644
81MP0000230_abnormal_systemic_arterial0.86077848
82MP0009250_abnormal_appendicular_skeleto0.85895627
83MP0001348_abnormal_lacrimal_gland0.85493109
84MP0004742_abnormal_vestibular_system0.82968899
85MP0003119_abnormal_digestive_system0.81616347
86MP0000534_abnormal_ureter_morphology0.78572641
87MP0001984_abnormal_olfaction0.78024143
88MP0001502_abnormal_circadian_rhythm0.77801997
89MP0001919_abnormal_reproductive_system0.77663948
90MP0002882_abnormal_neuron_morphology0.76509224
91MP0002234_abnormal_pharynx_morphology0.75844062
92MP0003879_abnormal_hair_cell0.75675404
93MP0002067_abnormal_sensory_capabilities0.75288783
94MP0001663_abnormal_digestive_system0.73509756
95MP0004859_abnormal_synaptic_plasticity0.73509600
96MP0002734_abnormal_mechanical_nocicepti0.72551304
97MP0003136_yellow_coat_color0.72284270
98MP0002210_abnormal_sex_determination0.70131118
99MP0002109_abnormal_limb_morphology0.69193967
100MP0002152_abnormal_brain_morphology0.66798666

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.93202263
2Acute necrotizing encephalopathy (HP:0006965)4.44854881
3Absent rod-and cone-mediated responses on ERG (HP:0007688)4.14531940
4Abnormality of cells of the erythroid lineage (HP:0012130)3.97655621
5Abnormal mitochondria in muscle tissue (HP:0008316)3.93846476
6Acute encephalopathy (HP:0006846)3.81840286
7Progressive macrocephaly (HP:0004481)3.64836395
8Abnormal rod and cone electroretinograms (HP:0008323)3.57246625
9Pendular nystagmus (HP:0012043)3.48438989
10Mitochondrial inheritance (HP:0001427)3.45061954
11Abnormality of midbrain morphology (HP:0002418)3.40043867
12Molar tooth sign on MRI (HP:0002419)3.40043867
13Macrocytic anemia (HP:0001972)3.35070936
14Stenosis of the external auditory canal (HP:0000402)3.26109173
15Nephronophthisis (HP:0000090)3.19833691
16Pancreatic fibrosis (HP:0100732)3.14916259
17Hepatocellular necrosis (HP:0001404)3.13614443
18Pallor (HP:0000980)3.11211255
19Increased CSF lactate (HP:0002490)2.91600125
20Medial flaring of the eyebrow (HP:0010747)2.88485525
21Myokymia (HP:0002411)2.85555385
22Abnormal number of erythroid precursors (HP:0012131)2.76202598
23Keratoconus (HP:0000563)2.71690711
24Increased corneal curvature (HP:0100692)2.71690711
25Pancreatic cysts (HP:0001737)2.71214088
26Septo-optic dysplasia (HP:0100842)2.70660472
27Decreased central vision (HP:0007663)2.70043844
28Anencephaly (HP:0002323)2.62835457
29Hepatic necrosis (HP:0002605)2.61491139
30Cerebral edema (HP:0002181)2.57077222
31Congenital stationary night blindness (HP:0007642)2.57061176
32True hermaphroditism (HP:0010459)2.53840074
33Maternal diabetes (HP:0009800)2.51148965
34Adrenal hypoplasia (HP:0000835)2.47130425
35Optic disc pallor (HP:0000543)2.45036609
36Abnormality of the renal medulla (HP:0100957)2.41290869
37Abnormality of alanine metabolism (HP:0010916)2.36279490
38Hyperalaninemia (HP:0003348)2.36279490
39Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.36279490
40Agitation (HP:0000713)2.34491957
41Aplasia/Hypoplasia of the sacrum (HP:0008517)2.34285615
42Aplasia/Hypoplasia of the spleen (HP:0010451)2.33188992
43Dynein arm defect of respiratory motile cilia (HP:0012255)2.28824253
44Absent/shortened dynein arms (HP:0200106)2.28824253
45Palpebral edema (HP:0100540)2.28503172
46Asplenia (HP:0001746)2.26521887
47Abnormal ciliary motility (HP:0012262)2.25906507
48Absent thumb (HP:0009777)2.21199911
49Sclerocornea (HP:0000647)2.20363002
50Decreased electroretinogram (ERG) amplitude (HP:0000654)2.19250133
51Constricted visual fields (HP:0001133)2.17836520
52Type 2 muscle fiber atrophy (HP:0003554)2.16975170
53Myotonia (HP:0002486)2.15453204
54Abnormal respiratory epithelium morphology (HP:0012253)2.14191199
55Abnormal respiratory motile cilium morphology (HP:0005938)2.14191199
56Gait imbalance (HP:0002141)2.12618210
57Abnormality of DNA repair (HP:0003254)2.11337932
58Type II lissencephaly (HP:0007260)2.11105066
59Chronic hepatic failure (HP:0100626)2.10506503
60Nephrogenic diabetes insipidus (HP:0009806)2.07606803
61Hyperglycinemia (HP:0002154)2.07236048
62Postaxial foot polydactyly (HP:0001830)2.05200307
63Abnormality of the phalanges of the 5th finger (HP:0004213)2.03387535
64Hypoplasia of the ulna (HP:0003022)2.00032645
65Attenuation of retinal blood vessels (HP:0007843)1.99117040
66Increased serum lactate (HP:0002151)1.97533956
67Congenital primary aphakia (HP:0007707)1.97391030
68Abnormal respiratory motile cilium physiology (HP:0012261)1.92772019
69Lipid accumulation in hepatocytes (HP:0006561)1.90150271
70Depressed nasal ridge (HP:0000457)1.89829587
71Leukodystrophy (HP:0002415)1.89341490
72Severe visual impairment (HP:0001141)1.87977262
73Short femoral neck (HP:0100864)1.87934988
74Lissencephaly (HP:0001339)1.87387227
75Tubular atrophy (HP:0000092)1.86824863
76Limb dystonia (HP:0002451)1.86750699
77Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.86423834
78Increased hepatocellular lipid droplets (HP:0006565)1.84040781
79Dyskinesia (HP:0100660)1.80405119
80Abolished electroretinogram (ERG) (HP:0000550)1.80344945
81Thyroid-stimulating hormone excess (HP:0002925)1.80170284
82Lactic acidosis (HP:0003128)1.79355113
83Oligomenorrhea (HP:0000876)1.79331238
84Exercise intolerance (HP:0003546)1.78507628
85Abnormality of the proximal phalanges of the hand (HP:0009834)1.77270756
86Optic nerve hypoplasia (HP:0000609)1.76984100
87Supernumerary spleens (HP:0009799)1.76632278
88Cerebral hypomyelination (HP:0006808)1.76366201
893-Methylglutaconic aciduria (HP:0003535)1.75686484
90Short tibia (HP:0005736)1.74304244
91Abnormality of the phalanges of the 2nd finger (HP:0009541)1.73982580
92Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.73001318
93Abnormality of the renal cortex (HP:0011035)1.72854436
94Anophthalmia (HP:0000528)1.72123763
95Muscle fiber atrophy (HP:0100295)1.71545582
96Hip dysplasia (HP:0001385)1.70404654
97Pachygyria (HP:0001302)1.70176971
98Hypoplasia of the radius (HP:0002984)1.70084814
99Porencephaly (HP:0002132)1.69769065
100Holoprosencephaly (HP:0001360)1.69593695

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.30196240
2WNK43.29181067
3NME22.90770274
4PIK3CA2.65066659
5MAP4K22.29966948
6DYRK22.19989098
7NUAK12.13813763
8TIE12.09015083
9TXK1.93761701
10PINK11.91188236
11CDK191.78768304
12ADRBK21.76831915
13PHKG11.75869394
14PHKG21.75869394
15GRK11.67591827
16MAP3K121.65415615
17CASK1.63664966
18VRK21.58773749
19EPHB21.57187404
20BCKDK1.56249387
21MAP2K71.55915506
22STK391.52834490
23FRK1.50793502
24MAP3K41.47847651
25DYRK1B1.45960279
26WNK31.45741832
27NTRK21.45691296
28LIMK11.41473366
29TLK11.36449354
30MAP3K111.34140321
31DYRK31.19215375
32BRAF1.17641116
33PRKCG1.15483076
34MAPK131.14375255
35MUSK1.12050324
36CAMK1D1.10028842
37CSNK1G21.08669504
38ZAK1.06847217
39CAMK11.04409918
40EPHA41.03976064
41LRRK21.02386797
42INSRR1.02020125
43NTRK30.97970685
44PRKCQ0.95443507
45CSNK1G30.95399871
46SGK2230.94503223
47SGK4940.94503223
48WNK10.93274028
49TRIM280.90661198
50CAMKK20.87037310
51TYRO30.86618439
52OBSCN0.86448168
53MINK10.85287782
54MAPKAPK50.84103569
55ADRBK10.81371852
56BMPR1B0.80620445
57STK240.74394153
58AURKA0.74259280
59PDK20.74226809
60VRK10.73825740
61PRKACA0.73678927
62PIM20.73281446
63PASK0.72674805
64CAMK1G0.72559745
65TAOK30.72408996
66DAPK30.72348670
67CSNK1G10.71959618
68CDC70.63053494
69STK110.62864560
70CSNK1A1L0.61265189
71PKN10.59882625
72MARK10.59867796
73TNIK0.58354301
74CSNK2A20.55941428
75ARAF0.54941025
76TEC0.52822003
77SGK20.52668467
78OXSR10.51944894
79SGK10.51428250
80ABL20.51414905
81RPS6KA50.51355574
82NME10.51299984
83DMPK0.49336280
84NEK10.47180254
85CAMK2A0.46439544
86CSNK1A10.46045762
87RPS6KA60.45755959
88CHEK20.44770700
89MAP2K40.44544870
90BCR0.43372139
91PRKCA0.42613508
92CSNK2A10.41621121
93MAP3K90.40245172
94ITK0.38787353
95PRKCD0.38615741
96DYRK1A0.38506022
97PRKCH0.37633741
98PLK20.37059755
99MAPK150.36951496
100ILK0.36027183

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.21124023
2Oxidative phosphorylation_Homo sapiens_hsa001904.33751201
3Parkinsons disease_Homo sapiens_hsa050123.46749150
4Cardiac muscle contraction_Homo sapiens_hsa042602.80829375
5Protein export_Homo sapiens_hsa030602.74428310
6Huntingtons disease_Homo sapiens_hsa050162.41252588
7Alzheimers disease_Homo sapiens_hsa050102.39039114
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.38690019
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.20784205
10RNA polymerase_Homo sapiens_hsa030201.97333773
11Proteasome_Homo sapiens_hsa030501.97230831
12Asthma_Homo sapiens_hsa053101.96426842
13Sulfur relay system_Homo sapiens_hsa041221.89829730
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.83674495
15Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.75653038
16Phototransduction_Homo sapiens_hsa047441.73634121
17RNA degradation_Homo sapiens_hsa030181.69170196
18Collecting duct acid secretion_Homo sapiens_hsa049661.62585711
19Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.60047206
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.52666001
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.40519914
22Linoleic acid metabolism_Homo sapiens_hsa005911.27553214
23Fanconi anemia pathway_Homo sapiens_hsa034601.26923769
24Homologous recombination_Homo sapiens_hsa034401.25311394
25Basal transcription factors_Homo sapiens_hsa030221.25258725
26One carbon pool by folate_Homo sapiens_hsa006701.16414970
27Pyrimidine metabolism_Homo sapiens_hsa002401.16010116
28Morphine addiction_Homo sapiens_hsa050321.15632275
29Nicotine addiction_Homo sapiens_hsa050331.13678256
30Peroxisome_Homo sapiens_hsa041461.07126251
31Allograft rejection_Homo sapiens_hsa053301.04928434
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.04327005
33Hedgehog signaling pathway_Homo sapiens_hsa043401.03788360
34Butanoate metabolism_Homo sapiens_hsa006501.02667602
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.01598775
36Basal cell carcinoma_Homo sapiens_hsa052171.01124833
37Regulation of autophagy_Homo sapiens_hsa041401.00973871
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00742159
39Autoimmune thyroid disease_Homo sapiens_hsa053200.98341040
40Olfactory transduction_Homo sapiens_hsa047400.97599535
41Nitrogen metabolism_Homo sapiens_hsa009100.96815882
42Graft-versus-host disease_Homo sapiens_hsa053320.95291679
43Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.94600631
44alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.92276753
45Purine metabolism_Homo sapiens_hsa002300.87529529
46Type I diabetes mellitus_Homo sapiens_hsa049400.85420209
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.82850398
48Rheumatoid arthritis_Homo sapiens_hsa053230.82494253
49Nucleotide excision repair_Homo sapiens_hsa034200.80658082
50GABAergic synapse_Homo sapiens_hsa047270.78161862
51Tryptophan metabolism_Homo sapiens_hsa003800.77062470
52Pyruvate metabolism_Homo sapiens_hsa006200.76251469
53Selenocompound metabolism_Homo sapiens_hsa004500.72679351
54Insulin secretion_Homo sapiens_hsa049110.72377011
55Propanoate metabolism_Homo sapiens_hsa006400.71945526
56Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.71269674
57Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.71230926
58Dopaminergic synapse_Homo sapiens_hsa047280.70980052
59Serotonergic synapse_Homo sapiens_hsa047260.67791838
60Metabolic pathways_Homo sapiens_hsa011000.65541638
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64404491
62Ether lipid metabolism_Homo sapiens_hsa005650.62398676
63Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.61180381
64Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.60252846
65Caffeine metabolism_Homo sapiens_hsa002320.60210972
66Synaptic vesicle cycle_Homo sapiens_hsa047210.59649615
67Arachidonic acid metabolism_Homo sapiens_hsa005900.59232465
68Fat digestion and absorption_Homo sapiens_hsa049750.58748461
69Chemical carcinogenesis_Homo sapiens_hsa052040.58541817
70Spliceosome_Homo sapiens_hsa030400.57023174
71Folate biosynthesis_Homo sapiens_hsa007900.55951032
72Retinol metabolism_Homo sapiens_hsa008300.55447908
73Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.54976509
74Glutamatergic synapse_Homo sapiens_hsa047240.53238142
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.51183580
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.50125404
77Circadian entrainment_Homo sapiens_hsa047130.47970427
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.47685235
79Taste transduction_Homo sapiens_hsa047420.46785036
80Steroid biosynthesis_Homo sapiens_hsa001000.46683279
81Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.46489689
82Salivary secretion_Homo sapiens_hsa049700.45937321
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.45368468
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43998519
85RNA transport_Homo sapiens_hsa030130.42315790
86Cholinergic synapse_Homo sapiens_hsa047250.35388245
87Hippo signaling pathway_Homo sapiens_hsa043900.34809248
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.34266829
89Wnt signaling pathway_Homo sapiens_hsa043100.33308400
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.31137936
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.30400794
92Notch signaling pathway_Homo sapiens_hsa043300.29597646
93Axon guidance_Homo sapiens_hsa043600.27893741
94Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27885450
95Mismatch repair_Homo sapiens_hsa034300.26756125
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.26081263
97Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.26075562
98Sulfur metabolism_Homo sapiens_hsa009200.25465534
99Oxytocin signaling pathway_Homo sapiens_hsa049210.25169388
100Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23801070

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »