

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 6.87166829 |
| 2 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.19516373 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.86913667 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.86913667 |
| 5 | viral transcription (GO:0019083) | 5.68059632 |
| 6 | translational termination (GO:0006415) | 5.45733852 |
| 7 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.37579737 |
| 8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.14062650 |
| 9 | cotranslational protein targeting to membrane (GO:0006613) | 5.05832264 |
| 10 | protein targeting to ER (GO:0045047) | 5.05048849 |
| 11 | respiratory electron transport chain (GO:0022904) | 4.96883492 |
| 12 | electron transport chain (GO:0022900) | 4.88345029 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 4.82442162 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.82251877 |
| 15 | translational elongation (GO:0006414) | 4.70695289 |
| 16 | DNA deamination (GO:0045006) | 4.53625650 |
| 17 | maturation of SSU-rRNA (GO:0030490) | 4.42605246 |
| 18 | protein neddylation (GO:0045116) | 4.41709224 |
| 19 | ribosomal large subunit biogenesis (GO:0042273) | 4.28326512 |
| 20 | response to pheromone (GO:0019236) | 4.05416191 |
| 21 | protein complex biogenesis (GO:0070271) | 4.03117415 |
| 22 | ribosomal small subunit biogenesis (GO:0042274) | 4.01206261 |
| 23 | cellular protein complex disassembly (GO:0043624) | 4.00468454 |
| 24 | viral life cycle (GO:0019058) | 3.97260489 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.86536713 |
| 26 | chaperone-mediated protein transport (GO:0072321) | 3.85551034 |
| 27 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.81674167 |
| 28 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.81284268 |
| 29 | platelet dense granule organization (GO:0060155) | 3.74507518 |
| 30 | translational initiation (GO:0006413) | 3.74318549 |
| 31 | cytidine deamination (GO:0009972) | 3.63102454 |
| 32 | cytidine metabolic process (GO:0046087) | 3.63102454 |
| 33 | cytidine catabolic process (GO:0006216) | 3.63102454 |
| 34 | translation (GO:0006412) | 3.57714133 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.56302883 |
| 36 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.56302883 |
| 37 | NADH dehydrogenase complex assembly (GO:0010257) | 3.56302883 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.54090233 |
| 39 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.50128616 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.50128616 |
| 41 | hydrogen ion transmembrane transport (GO:1902600) | 3.48238761 |
| 42 | ATP biosynthetic process (GO:0006754) | 3.40396932 |
| 43 | protein targeting to membrane (GO:0006612) | 3.30380993 |
| 44 | GPI anchor metabolic process (GO:0006505) | 3.26830914 |
| 45 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.26054958 |
| 46 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.25686826 |
| 47 | proton transport (GO:0015992) | 3.24834266 |
| 48 | GPI anchor biosynthetic process (GO:0006506) | 3.22657821 |
| 49 | protein complex disassembly (GO:0043241) | 3.19517407 |
| 50 | hydrogen transport (GO:0006818) | 3.19162853 |
| 51 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.16928354 |
| 52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.15669836 |
| 53 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.14124805 |
| 54 | behavioral response to nicotine (GO:0035095) | 3.12154111 |
| 55 | respiratory chain complex IV assembly (GO:0008535) | 3.10353312 |
| 56 | macromolecular complex disassembly (GO:0032984) | 3.07473469 |
| 57 | cytochrome complex assembly (GO:0017004) | 3.06676833 |
| 58 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.02463651 |
| 59 | iron-sulfur cluster assembly (GO:0016226) | 3.01791162 |
| 60 | metallo-sulfur cluster assembly (GO:0031163) | 3.01791162 |
| 61 | termination of RNA polymerase III transcription (GO:0006386) | 3.01080393 |
| 62 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.01080393 |
| 63 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.00986518 |
| 64 | proteasome assembly (GO:0043248) | 3.00400332 |
| 65 | mast cell activation (GO:0045576) | 2.98802556 |
| 66 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.98718396 |
| 67 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.92660090 |
| 68 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.89437487 |
| 69 | axoneme assembly (GO:0035082) | 2.87176826 |
| 70 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.83531561 |
| 71 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.83490146 |
| 72 | regulation of hypersensitivity (GO:0002883) | 2.82620760 |
| 73 | base-excision repair, AP site formation (GO:0006285) | 2.81627296 |
| 74 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.81449183 |
| 75 | sequestering of actin monomers (GO:0042989) | 2.79217065 |
| 76 | negative regulation of heart rate (GO:0010459) | 2.78673060 |
| 77 | negative regulation of mast cell activation (GO:0033004) | 2.72410637 |
| 78 | mast cell degranulation (GO:0043303) | 2.69530697 |
| 79 | mast cell activation involved in immune response (GO:0002279) | 2.69530697 |
| 80 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.68113198 |
| 81 | mRNA catabolic process (GO:0006402) | 2.62053743 |
| 82 | spliceosomal complex assembly (GO:0000245) | 2.58763404 |
| 83 | cellular component biogenesis (GO:0044085) | 2.57609125 |
| 84 | regulation of cellular respiration (GO:0043457) | 2.56513554 |
| 85 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.55299402 |
| 86 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.54706750 |
| 87 | one-carbon compound transport (GO:0019755) | 2.53884895 |
| 88 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.52467439 |
| 89 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.49601173 |
| 90 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.48509071 |
| 91 | regulation of activation of Janus kinase activity (GO:0010533) | 2.46805683 |
| 92 | deoxyribose phosphate catabolic process (GO:0046386) | 2.45829181 |
| 93 | GTP biosynthetic process (GO:0006183) | 2.42611187 |
| 94 | forebrain morphogenesis (GO:0048853) | 2.42273190 |
| 95 | signal peptide processing (GO:0006465) | 2.41364528 |
| 96 | RNA catabolic process (GO:0006401) | 2.41315622 |
| 97 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.40723673 |
| 98 | mannosylation (GO:0097502) | 2.40386365 |
| 99 | anterograde synaptic vesicle transport (GO:0048490) | 2.39798315 |
| 100 | kynurenine metabolic process (GO:0070189) | 2.39702308 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.61536114 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.53097868 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.15560881 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.00285338 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 2.84080994 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.82946588 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.74995508 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.53854228 |
| 9 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.51509075 |
| 10 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.46406834 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.43545962 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.33231939 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25303093 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.17846817 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.11120589 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.05576192 |
| 17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.00727724 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.95730836 |
| 19 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.91648723 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.88624734 |
| 21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.85665791 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.85088848 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.67825956 |
| 24 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.64814121 |
| 25 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.63242511 |
| 26 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.62943053 |
| 27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.61899712 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.61897450 |
| 29 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.56736576 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 1.55595428 |
| 31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.54664938 |
| 32 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.53553271 |
| 33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.49843601 |
| 34 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.46993491 |
| 35 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.46993491 |
| 36 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.46244092 |
| 37 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.46066423 |
| 38 | AR_20517297_ChIP-Seq_VCAP_Human | 1.41091117 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40708926 |
| 40 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.40392766 |
| 41 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.39683080 |
| 42 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.37257822 |
| 43 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.36568423 |
| 44 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.35771418 |
| 45 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.35646963 |
| 46 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.35583981 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.34039626 |
| 48 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.33654557 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.31283972 |
| 50 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.28448523 |
| 51 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.28348777 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.28348777 |
| 53 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.26108912 |
| 54 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.24875768 |
| 55 | NCOR_22424771_ChIP-Seq_293T_Human | 1.22533792 |
| 56 | GATA3_26560356_Chip-Seq_TH2_Human | 1.22476406 |
| 57 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.21676093 |
| 58 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.21139274 |
| 59 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.18186318 |
| 60 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.18186318 |
| 61 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17378592 |
| 62 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.17156631 |
| 63 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.15955701 |
| 64 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15496268 |
| 65 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.15266537 |
| 66 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.14313200 |
| 67 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.14173070 |
| 68 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13449138 |
| 69 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.12756719 |
| 70 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.09849669 |
| 71 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.09172365 |
| 72 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.09163678 |
| 73 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.08862817 |
| 74 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.07701956 |
| 75 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07465646 |
| 76 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.06121654 |
| 77 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.04049924 |
| 78 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.03961884 |
| 79 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.03921565 |
| 80 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.02936694 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.02837515 |
| 82 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.01961806 |
| 83 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.00429066 |
| 84 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.00046322 |
| 85 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99217778 |
| 86 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.98550553 |
| 87 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.97651573 |
| 88 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.97107300 |
| 89 | MYB_26560356_Chip-Seq_TH2_Human | 0.96944410 |
| 90 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96291643 |
| 91 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.96271025 |
| 92 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.95527648 |
| 93 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.94244343 |
| 94 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.94054464 |
| 95 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93294605 |
| 96 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.93287454 |
| 97 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.92852864 |
| 98 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.91562793 |
| 99 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.91403133 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91266613 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.14836786 |
| 2 | MP0005671_abnormal_response_to | 3.67915323 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.02507424 |
| 4 | MP0006292_abnormal_olfactory_placode | 2.96689364 |
| 5 | MP0004147_increased_porphyrin_level | 2.66405548 |
| 6 | MP0005645_abnormal_hypothalamus_physiol | 2.48105156 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.41804525 |
| 8 | MP0005646_abnormal_pituitary_gland | 2.24766520 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.22153624 |
| 10 | MP0003646_muscle_fatigue | 1.96685486 |
| 11 | MP0008877_abnormal_DNA_methylation | 1.90076915 |
| 12 | MP0002163_abnormal_gland_morphology | 1.87250074 |
| 13 | MP0009785_altered_susceptibility_to | 1.86755633 |
| 14 | MP0004142_abnormal_muscle_tone | 1.82589974 |
| 15 | MP0004145_abnormal_muscle_electrophysio | 1.76419985 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.75135200 |
| 17 | MP0008872_abnormal_physiological_respon | 1.74241643 |
| 18 | MP0000372_irregular_coat_pigmentation | 1.72255167 |
| 19 | MP0003787_abnormal_imprinting | 1.71033110 |
| 20 | MP0002876_abnormal_thyroid_physiology | 1.68243673 |
| 21 | MP0002102_abnormal_ear_morphology | 1.64245959 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.59689395 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.57126364 |
| 24 | MP0001800_abnormal_humoral_immune | 1.54753544 |
| 25 | MP0001905_abnormal_dopamine_level | 1.53977271 |
| 26 | MP0005379_endocrine/exocrine_gland_phen | 1.52404161 |
| 27 | MP0003011_delayed_dark_adaptation | 1.48639489 |
| 28 | MP0005389_reproductive_system_phenotype | 1.41045271 |
| 29 | MP0003880_abnormal_central_pattern | 1.40386209 |
| 30 | MP0005253_abnormal_eye_physiology | 1.38323502 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.35958693 |
| 32 | MP0008789_abnormal_olfactory_epithelium | 1.35180027 |
| 33 | MP0003195_calcinosis | 1.34959212 |
| 34 | MP0005377_hearing/vestibular/ear_phenot | 1.33711615 |
| 35 | MP0003878_abnormal_ear_physiology | 1.33711615 |
| 36 | MP0006276_abnormal_autonomic_nervous | 1.31728347 |
| 37 | MP0002166_altered_tumor_susceptibility | 1.30438644 |
| 38 | MP0001873_stomach_inflammation | 1.29496589 |
| 39 | MP0006036_abnormal_mitochondrial_physio | 1.29264609 |
| 40 | MP0003763_abnormal_thymus_physiology | 1.27753517 |
| 41 | MP0005084_abnormal_gallbladder_morpholo | 1.26921564 |
| 42 | MP0000631_abnormal_neuroendocrine_gland | 1.26320830 |
| 43 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25586447 |
| 44 | MP0010386_abnormal_urinary_bladder | 1.25228475 |
| 45 | MP0001968_abnormal_touch/_nociception | 1.23573564 |
| 46 | MP0002160_abnormal_reproductive_system | 1.23527421 |
| 47 | MP0005000_abnormal_immune_tolerance | 1.22777229 |
| 48 | MP0001919_abnormal_reproductive_system | 1.20507070 |
| 49 | MP0002736_abnormal_nociception_after | 1.20120308 |
| 50 | MP0001764_abnormal_homeostasis | 1.16821303 |
| 51 | MP0002006_tumorigenesis | 1.15675635 |
| 52 | MP0001790_abnormal_immune_system | 1.15209262 |
| 53 | MP0005387_immune_system_phenotype | 1.15209262 |
| 54 | MP0003806_abnormal_nucleotide_metabolis | 1.14261031 |
| 55 | MP0001485_abnormal_pinna_reflex | 1.13798728 |
| 56 | MP0000685_abnormal_immune_system | 1.13613100 |
| 57 | MP0002723_abnormal_immune_serum | 1.12902143 |
| 58 | MP0001529_abnormal_vocalization | 1.10451900 |
| 59 | MP0008995_early_reproductive_senescence | 1.07991924 |
| 60 | MP0001819_abnormal_immune_cell | 1.06854687 |
| 61 | MP0002452_abnormal_antigen_presenting | 1.06644906 |
| 62 | MP0001986_abnormal_taste_sensitivity | 1.06299442 |
| 63 | MP0002420_abnormal_adaptive_immunity | 1.05863767 |
| 64 | MP0000516_abnormal_urinary_system | 1.04233652 |
| 65 | MP0005367_renal/urinary_system_phenotyp | 1.04233652 |
| 66 | MP0009764_decreased_sensitivity_to | 1.02143996 |
| 67 | MP0004885_abnormal_endolymph | 1.01787623 |
| 68 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01701553 |
| 69 | MP0001188_hyperpigmentation | 1.01610065 |
| 70 | MP0002272_abnormal_nervous_system | 1.00242356 |
| 71 | MP0003186_abnormal_redox_activity | 0.99558290 |
| 72 | MP0003866_abnormal_defecation | 0.98107150 |
| 73 | MP0001765_abnormal_ion_homeostasis | 0.98007648 |
| 74 | MP0009745_abnormal_behavioral_response | 0.97659094 |
| 75 | MP0005636_abnormal_mineral_homeostasis | 0.96648674 |
| 76 | MP0002138_abnormal_hepatobiliary_system | 0.96215623 |
| 77 | MP0002095_abnormal_skin_pigmentation | 0.96145771 |
| 78 | MP0005025_abnormal_response_to | 0.94649851 |
| 79 | MP0001486_abnormal_startle_reflex | 0.94389911 |
| 80 | MP0002638_abnormal_pupillary_reflex | 0.92011314 |
| 81 | MP0001970_abnormal_pain_threshold | 0.91628329 |
| 82 | MP0006082_CNS_inflammation | 0.90387899 |
| 83 | MP0002653_abnormal_ependyma_morphology | 0.87638353 |
| 84 | MP0001501_abnormal_sleep_pattern | 0.85264921 |
| 85 | MP0003283_abnormal_digestive_organ | 0.82314355 |
| 86 | MP0001293_anophthalmia | 0.82132300 |
| 87 | MP0002277_abnormal_respiratory_mucosa | 0.81652274 |
| 88 | MP0001984_abnormal_olfaction | 0.80243489 |
| 89 | MP0005410_abnormal_fertilization | 0.79301442 |
| 90 | MP0005332_abnormal_amino_acid | 0.77483352 |
| 91 | MP0002693_abnormal_pancreas_physiology | 0.76976893 |
| 92 | MP0001440_abnormal_grooming_behavior | 0.76184809 |
| 93 | MP0003252_abnormal_bile_duct | 0.76094920 |
| 94 | MP0002234_abnormal_pharynx_morphology | 0.75933457 |
| 95 | MP0002733_abnormal_thermal_nociception | 0.75698099 |
| 96 | MP0000716_abnormal_immune_system | 0.75418129 |
| 97 | MP0002909_abnormal_adrenal_gland | 0.75044480 |
| 98 | MP0003122_maternal_imprinting | 0.74812871 |
| 99 | MP0000230_abnormal_systemic_arterial | 0.74807406 |
| 100 | MP0005085_abnormal_gallbladder_physiolo | 0.71811924 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.80838655 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.53836104 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.25720176 |
| 4 | Acute encephalopathy (HP:0006846) | 4.11707302 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.09124432 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.97320923 |
| 7 | Increased CSF lactate (HP:0002490) | 3.87941973 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.84388549 |
| 9 | 3-Methylglutaconic aciduria (HP:0003535) | 3.82581717 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.74793023 |
| 11 | Increased intramyocellular lipid droplets (HP:0012240) | 3.55133977 |
| 12 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.45256200 |
| 13 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.45256200 |
| 14 | Hepatic necrosis (HP:0002605) | 3.43941786 |
| 15 | Lipid accumulation in hepatocytes (HP:0006561) | 3.37218221 |
| 16 | Aplastic anemia (HP:0001915) | 3.30045988 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.29757906 |
| 18 | Congenital stationary night blindness (HP:0007642) | 3.29134380 |
| 19 | Congenital, generalized hypertrichosis (HP:0004540) | 3.27288099 |
| 20 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.17621070 |
| 21 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.14823542 |
| 22 | Pancreatic cysts (HP:0001737) | 3.06492429 |
| 23 | Cerebral edema (HP:0002181) | 3.05170196 |
| 24 | Reticulocytopenia (HP:0001896) | 3.03298417 |
| 25 | Macrocytic anemia (HP:0001972) | 2.94376248 |
| 26 | Molar tooth sign on MRI (HP:0002419) | 2.93130704 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.93130704 |
| 28 | Exertional dyspnea (HP:0002875) | 2.92519102 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.92146433 |
| 30 | Abolished electroretinogram (ERG) (HP:0000550) | 2.77671308 |
| 31 | Abnormal number of erythroid precursors (HP:0012131) | 2.76918921 |
| 32 | IgG deficiency (HP:0004315) | 2.72742655 |
| 33 | Optic disc pallor (HP:0000543) | 2.69887543 |
| 34 | Methylmalonic acidemia (HP:0002912) | 2.55466293 |
| 35 | Constricted visual fields (HP:0001133) | 2.52021084 |
| 36 | True hermaphroditism (HP:0010459) | 2.48661301 |
| 37 | Hypoproteinemia (HP:0003075) | 2.47617382 |
| 38 | Pancreatic fibrosis (HP:0100732) | 2.45917763 |
| 39 | Abnormal ciliary motility (HP:0012262) | 2.42623302 |
| 40 | Attenuation of retinal blood vessels (HP:0007843) | 2.39853309 |
| 41 | Nephronophthisis (HP:0000090) | 2.39081584 |
| 42 | Decreased central vision (HP:0007663) | 2.38481959 |
| 43 | Abnormality of renal resorption (HP:0011038) | 2.36351977 |
| 44 | Lactic acidosis (HP:0003128) | 2.33152667 |
| 45 | Increased serum lactate (HP:0002151) | 2.32805328 |
| 46 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.32463044 |
| 47 | Medial flaring of the eyebrow (HP:0010747) | 2.31689015 |
| 48 | Pallor (HP:0000980) | 2.31325034 |
| 49 | Stomatitis (HP:0010280) | 2.27777253 |
| 50 | Abnormality of B cell number (HP:0010975) | 2.26870864 |
| 51 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.23050977 |
| 52 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.22426982 |
| 53 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.22426982 |
| 54 | Severe combined immunodeficiency (HP:0004430) | 2.21335232 |
| 55 | Respiratory failure (HP:0002878) | 2.20313313 |
| 56 | Thyroiditis (HP:0100646) | 2.18183115 |
| 57 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.17457930 |
| 58 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.17220758 |
| 59 | Abnormality of the prostate (HP:0008775) | 2.16488740 |
| 60 | Leukodystrophy (HP:0002415) | 2.14806813 |
| 61 | Abnormality of the renal cortex (HP:0011035) | 2.13466749 |
| 62 | Hyperglycinemia (HP:0002154) | 2.13260563 |
| 63 | Stenosis of the external auditory canal (HP:0000402) | 2.08026664 |
| 64 | Exercise intolerance (HP:0003546) | 2.07036306 |
| 65 | Lethargy (HP:0001254) | 2.06953595 |
| 66 | Abnormality of urine glucose concentration (HP:0011016) | 2.03800702 |
| 67 | Glycosuria (HP:0003076) | 2.03800702 |
| 68 | Hyperphosphaturia (HP:0003109) | 2.02208234 |
| 69 | Absent/shortened dynein arms (HP:0200106) | 2.01571589 |
| 70 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.01571589 |
| 71 | Abnormality of T cell number (HP:0011839) | 1.97209971 |
| 72 | Type II lissencephaly (HP:0007260) | 1.96557910 |
| 73 | Renal cortical cysts (HP:0000803) | 1.93017693 |
| 74 | Abnormality of macular pigmentation (HP:0008002) | 1.92348402 |
| 75 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.90854385 |
| 76 | Oral leukoplakia (HP:0002745) | 1.90490982 |
| 77 | Abnormality of the renal medulla (HP:0100957) | 1.89773403 |
| 78 | Respiratory difficulties (HP:0002880) | 1.89743436 |
| 79 | B lymphocytopenia (HP:0010976) | 1.89636363 |
| 80 | Pendular nystagmus (HP:0012043) | 1.89533793 |
| 81 | T lymphocytopenia (HP:0005403) | 1.89112714 |
| 82 | Chronic sinusitis (HP:0011109) | 1.88164330 |
| 83 | Methylmalonic aciduria (HP:0012120) | 1.87617549 |
| 84 | Abnormal hemoglobin (HP:0011902) | 1.86159098 |
| 85 | Increased IgM level (HP:0003496) | 1.83765107 |
| 86 | Cerebral palsy (HP:0100021) | 1.83214920 |
| 87 | Metaphyseal dysplasia (HP:0100255) | 1.82200858 |
| 88 | Absent thumb (HP:0009777) | 1.80216057 |
| 89 | Type 2 muscle fiber atrophy (HP:0003554) | 1.76341341 |
| 90 | Pancytopenia (HP:0001876) | 1.75341461 |
| 91 | Male pseudohermaphroditism (HP:0000037) | 1.73045198 |
| 92 | Sclerocornea (HP:0000647) | 1.72215169 |
| 93 | Hypothermia (HP:0002045) | 1.71764611 |
| 94 | Generalized aminoaciduria (HP:0002909) | 1.70147843 |
| 95 | Autoimmune hemolytic anemia (HP:0001890) | 1.69689396 |
| 96 | Congenital primary aphakia (HP:0007707) | 1.68514360 |
| 97 | Abnormality of T cells (HP:0002843) | 1.65598442 |
| 98 | Polydipsia (HP:0001959) | 1.65219116 |
| 99 | Abnormal drinking behavior (HP:0030082) | 1.65219116 |
| 100 | Gait imbalance (HP:0002141) | 1.64825236 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 3.79626573 |
| 2 | KDR | 2.93833255 |
| 3 | TXK | 2.83657834 |
| 4 | MAP3K12 | 2.68535086 |
| 5 | GRK1 | 2.63778542 |
| 6 | ADRBK2 | 2.44582307 |
| 7 | ZAK | 2.39601527 |
| 8 | MAP4K2 | 2.37496493 |
| 9 | FRK | 2.35419941 |
| 10 | VRK2 | 2.31220597 |
| 11 | TLK1 | 2.28114000 |
| 12 | BCKDK | 1.86094400 |
| 13 | BMPR2 | 1.80762090 |
| 14 | BMPR1B | 1.73708329 |
| 15 | TESK2 | 1.65876001 |
| 16 | MYLK | 1.60656946 |
| 17 | STK16 | 1.60406563 |
| 18 | MAP4K1 | 1.59514000 |
| 19 | WNK3 | 1.58323630 |
| 20 | MUSK | 1.56242951 |
| 21 | TAOK3 | 1.55419665 |
| 22 | KIT | 1.42509010 |
| 23 | TEC | 1.41654355 |
| 24 | PINK1 | 1.40668021 |
| 25 | WNK4 | 1.40188518 |
| 26 | VRK1 | 1.35963199 |
| 27 | ITK | 1.33065044 |
| 28 | NUAK1 | 1.32495194 |
| 29 | TNK2 | 1.27544883 |
| 30 | ILK | 1.25183410 |
| 31 | INSRR | 1.23729351 |
| 32 | OXSR1 | 1.14101788 |
| 33 | TRPM7 | 1.10540612 |
| 34 | DYRK2 | 1.10433575 |
| 35 | DAPK3 | 1.04883064 |
| 36 | SYK | 1.04114037 |
| 37 | BTK | 1.03158596 |
| 38 | PASK | 1.01769110 |
| 39 | TIE1 | 0.99133104 |
| 40 | DAPK2 | 0.99062139 |
| 41 | MAP3K4 | 0.97562919 |
| 42 | PIK3CG | 0.96440385 |
| 43 | FLT3 | 0.91834301 |
| 44 | LYN | 0.90768193 |
| 45 | CSF1R | 0.90316183 |
| 46 | GRK7 | 0.89180558 |
| 47 | SCYL2 | 0.88696651 |
| 48 | RPS6KA5 | 0.88403374 |
| 49 | OBSCN | 0.86437361 |
| 50 | FES | 0.80628786 |
| 51 | GRK6 | 0.80555696 |
| 52 | MATK | 0.80023516 |
| 53 | EIF2AK3 | 0.78622217 |
| 54 | DAPK1 | 0.77759634 |
| 55 | PRKCQ | 0.76865312 |
| 56 | MAPK13 | 0.75633874 |
| 57 | IKBKB | 0.74421628 |
| 58 | RPS6KA4 | 0.73610916 |
| 59 | TRIM28 | 0.73608814 |
| 60 | CAMK1 | 0.73179735 |
| 61 | BUB1 | 0.71181405 |
| 62 | MST4 | 0.69976683 |
| 63 | LCK | 0.68599021 |
| 64 | CSNK1G1 | 0.67628403 |
| 65 | ERBB3 | 0.66961947 |
| 66 | LIMK1 | 0.64657894 |
| 67 | MKNK1 | 0.64269928 |
| 68 | STK39 | 0.63511630 |
| 69 | PRKACA | 0.60979120 |
| 70 | PRKCE | 0.59414228 |
| 71 | MKNK2 | 0.58008814 |
| 72 | CDK3 | 0.57642737 |
| 73 | CSNK1G2 | 0.56066094 |
| 74 | CSNK1G3 | 0.55493222 |
| 75 | MAP2K7 | 0.55394336 |
| 76 | CSNK2A2 | 0.55007367 |
| 77 | PRKCA | 0.52163349 |
| 78 | CSNK2A1 | 0.51785115 |
| 79 | PIK3CA | 0.49504516 |
| 80 | PIM1 | 0.49255019 |
| 81 | TNIK | 0.48801818 |
| 82 | MARK3 | 0.48563957 |
| 83 | PRKCG | 0.48556766 |
| 84 | ADRBK1 | 0.48162922 |
| 85 | PLK2 | 0.45871165 |
| 86 | PIM2 | 0.45489073 |
| 87 | MAP3K11 | 0.45084060 |
| 88 | PKN1 | 0.44596141 |
| 89 | NME1 | 0.44437911 |
| 90 | AURKB | 0.44169194 |
| 91 | CDK8 | 0.43680158 |
| 92 | IGF1R | 0.43028326 |
| 93 | CAMK2A | 0.42879113 |
| 94 | PRKG1 | 0.42245163 |
| 95 | PRKCD | 0.40245155 |
| 96 | ABL1 | 0.39153941 |
| 97 | PHKG1 | 0.39072400 |
| 98 | PHKG2 | 0.39072400 |
| 99 | ROCK1 | 0.38090520 |
| 100 | AURKA | 0.37234774 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.42276627 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.19254415 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.94887006 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.48704383 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.29240920 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 3.24099395 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.04536265 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.98958040 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.85289938 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.71533778 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.66909765 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.38463813 |
| 13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.36484672 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 2.26641879 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.19140317 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.05508284 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.00185484 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.91216810 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.81798410 |
| 20 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.61289536 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.57684559 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.46542346 |
| 23 | Homologous recombination_Homo sapiens_hsa03440 | 1.44996552 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.35681731 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.33095112 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.27926322 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.24806399 |
| 28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.18512794 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.14888914 |
| 30 | RNA degradation_Homo sapiens_hsa03018 | 1.09305059 |
| 31 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.08828495 |
| 32 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.01731526 |
| 33 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.94600114 |
| 34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.86425453 |
| 35 | Olfactory transduction_Homo sapiens_hsa04740 | 0.85977157 |
| 36 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.81340319 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.79745605 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.77832872 |
| 39 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76316270 |
| 40 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.74816119 |
| 41 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73802175 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72876173 |
| 43 | Basal transcription factors_Homo sapiens_hsa03022 | 0.72837994 |
| 44 | Leishmaniasis_Homo sapiens_hsa05140 | 0.72497219 |
| 45 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.70444088 |
| 46 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.69199799 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.68126205 |
| 48 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.67903738 |
| 49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.67059819 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.66476588 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63803754 |
| 52 | Nicotine addiction_Homo sapiens_hsa05033 | 0.63407815 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62586948 |
| 54 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.61958692 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61594001 |
| 56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58803936 |
| 57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.58781271 |
| 58 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.57648661 |
| 59 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.56842098 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.55353249 |
| 61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55230262 |
| 62 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.53721093 |
| 63 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.51871099 |
| 64 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51080646 |
| 65 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49370304 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.49269795 |
| 67 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.48174419 |
| 68 | Spliceosome_Homo sapiens_hsa03040 | 0.47866729 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.45120821 |
| 70 | Taste transduction_Homo sapiens_hsa04742 | 0.44815093 |
| 71 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.43208099 |
| 72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.42721022 |
| 73 | Mismatch repair_Homo sapiens_hsa03430 | 0.42264610 |
| 74 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.42188398 |
| 75 | Morphine addiction_Homo sapiens_hsa05032 | 0.40800668 |
| 76 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40350688 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.35051604 |
| 78 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.34874107 |
| 79 | Salivary secretion_Homo sapiens_hsa04970 | 0.32768418 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.31019799 |
| 81 | GABAergic synapse_Homo sapiens_hsa04727 | 0.29839217 |
| 82 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.29698886 |
| 83 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.28476904 |
| 84 | Base excision repair_Homo sapiens_hsa03410 | 0.27238545 |
| 85 | Malaria_Homo sapiens_hsa05144 | 0.27064432 |
| 86 | RNA transport_Homo sapiens_hsa03013 | 0.26342936 |
| 87 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25851758 |
| 88 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.25270618 |
| 89 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.24418658 |
| 90 | Circadian entrainment_Homo sapiens_hsa04713 | 0.20888243 |
| 91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.20735630 |
| 92 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.20501519 |
| 93 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.20373560 |
| 94 | Tuberculosis_Homo sapiens_hsa05152 | 0.19119838 |
| 95 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.18479375 |
| 96 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.18294096 |
| 97 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.17797833 |
| 98 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.15212323 |
| 99 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.15148708 |
| 100 | DNA replication_Homo sapiens_hsa03030 | 0.13305827 |

