

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit biogenesis (GO:0042274) | 8.66873481 |
| 2 | viral transcription (GO:0019083) | 8.42227864 |
| 3 | translational termination (GO:0006415) | 8.04176109 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 7.97680965 |
| 5 | maturation of SSU-rRNA (GO:0030490) | 7.66398214 |
| 6 | translational elongation (GO:0006414) | 6.57605870 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.54209419 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 6.48310798 |
| 9 | protein targeting to ER (GO:0045047) | 6.44391381 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.17879875 |
| 11 | cellular protein complex disassembly (GO:0043624) | 6.17288998 |
| 12 | protein localization to endoplasmic reticulum (GO:0070972) | 6.06614404 |
| 13 | viral life cycle (GO:0019058) | 5.98479026 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.87296747 |
| 15 | protein complex disassembly (GO:0043241) | 5.31351978 |
| 16 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.16663119 |
| 17 | macromolecular complex disassembly (GO:0032984) | 4.99907317 |
| 18 | behavioral response to nicotine (GO:0035095) | 4.97806622 |
| 19 | translational initiation (GO:0006413) | 4.92801006 |
| 20 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.62665790 |
| 21 | ATP synthesis coupled proton transport (GO:0015986) | 4.62665790 |
| 22 | protein neddylation (GO:0045116) | 4.53505861 |
| 23 | protein targeting to membrane (GO:0006612) | 4.39817372 |
| 24 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.38020205 |
| 25 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.38020205 |
| 26 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.29745776 |
| 27 | cell proliferation in forebrain (GO:0021846) | 4.13899176 |
| 28 | pattern specification involved in kidney development (GO:0061004) | 3.98850753 |
| 29 | chaperone-mediated protein transport (GO:0072321) | 3.95352943 |
| 30 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.94785131 |
| 31 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.94066694 |
| 32 | ribosomal large subunit biogenesis (GO:0042273) | 3.87586683 |
| 33 | nonmotile primary cilium assembly (GO:0035058) | 3.75718525 |
| 34 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.73929010 |
| 35 | mRNA catabolic process (GO:0006402) | 3.73054807 |
| 36 | epithelial cilium movement (GO:0003351) | 3.68815157 |
| 37 | translation (GO:0006412) | 3.59001110 |
| 38 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.55934706 |
| 39 | head development (GO:0060322) | 3.54779450 |
| 40 | establishment of mitochondrion localization (GO:0051654) | 3.52630724 |
| 41 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.50992543 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.50992543 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.50992543 |
| 44 | body morphogenesis (GO:0010171) | 3.47029023 |
| 45 | nucleobase catabolic process (GO:0046113) | 3.43771007 |
| 46 | tongue development (GO:0043586) | 3.41817881 |
| 47 | neuron fate determination (GO:0048664) | 3.33086125 |
| 48 | RNA catabolic process (GO:0006401) | 3.28861762 |
| 49 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.28211933 |
| 50 | protein complex biogenesis (GO:0070271) | 3.23907104 |
| 51 | axonal fasciculation (GO:0007413) | 3.22821328 |
| 52 | mitochondrion transport along microtubule (GO:0047497) | 3.21398879 |
| 53 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.21398879 |
| 54 | negative regulation of mast cell activation (GO:0033004) | 3.20307042 |
| 55 | regulation of cilium movement (GO:0003352) | 3.20295854 |
| 56 | regulation of microtubule-based movement (GO:0060632) | 3.17805477 |
| 57 | ncRNA 3-end processing (GO:0043628) | 3.17089123 |
| 58 | axonemal dynein complex assembly (GO:0070286) | 3.16828502 |
| 59 | cellular component biogenesis (GO:0044085) | 3.14677693 |
| 60 | respiratory electron transport chain (GO:0022904) | 3.14370780 |
| 61 | electron transport chain (GO:0022900) | 3.12876420 |
| 62 | response to redox state (GO:0051775) | 3.07872512 |
| 63 | hypothalamus development (GO:0021854) | 3.07097022 |
| 64 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.06671410 |
| 65 | GTP biosynthetic process (GO:0006183) | 3.05013543 |
| 66 | establishment of protein localization to membrane (GO:0090150) | 3.02622580 |
| 67 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.01872344 |
| 68 | cilium movement (GO:0003341) | 3.00918004 |
| 69 | cardiovascular system development (GO:0072358) | 3.00320793 |
| 70 | segment specification (GO:0007379) | 3.00068494 |
| 71 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.99801309 |
| 72 | synaptic transmission, cholinergic (GO:0007271) | 2.99402988 |
| 73 | spinal cord association neuron differentiation (GO:0021527) | 2.97519206 |
| 74 | short-term memory (GO:0007614) | 2.97032178 |
| 75 | positive regulation of respiratory burst (GO:0060267) | 2.96918924 |
| 76 | embryonic body morphogenesis (GO:0010172) | 2.95569969 |
| 77 | motile cilium assembly (GO:0044458) | 2.90730778 |
| 78 | somite development (GO:0061053) | 2.88001734 |
| 79 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.87230955 |
| 80 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.83272214 |
| 81 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.80801232 |
| 82 | protein polyglutamylation (GO:0018095) | 2.79637672 |
| 83 | intraciliary transport (GO:0042073) | 2.77969097 |
| 84 | protein targeting (GO:0006605) | 2.76810357 |
| 85 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.76538801 |
| 86 | neuron recognition (GO:0008038) | 2.76141222 |
| 87 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.71012531 |
| 88 | hydrogen ion transmembrane transport (GO:1902600) | 2.70742653 |
| 89 | auditory receptor cell differentiation (GO:0042491) | 2.68441716 |
| 90 | genetic imprinting (GO:0071514) | 2.63809447 |
| 91 | positive regulation of T cell apoptotic process (GO:0070234) | 2.61064762 |
| 92 | ATP biosynthetic process (GO:0006754) | 2.60275370 |
| 93 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.59914940 |
| 94 | establishment of protein localization to organelle (GO:0072594) | 2.55638188 |
| 95 | UTP biosynthetic process (GO:0006228) | 2.55032042 |
| 96 | axon ensheathment in central nervous system (GO:0032291) | 2.54862195 |
| 97 | central nervous system myelination (GO:0022010) | 2.54862195 |
| 98 | transmission of nerve impulse (GO:0019226) | 2.54858354 |
| 99 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.50491413 |
| 100 | retinal ganglion cell axon guidance (GO:0031290) | 2.48781272 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 7.79051236 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.28878046 |
| 3 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.71931185 |
| 4 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.44539348 |
| 5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.37329883 |
| 6 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.35314590 |
| 7 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.23754641 |
| 8 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.18303436 |
| 9 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.16506856 |
| 10 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.98199896 |
| 11 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.95604109 |
| 12 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.93909509 |
| 13 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.91988045 |
| 14 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.91213510 |
| 15 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.84181276 |
| 16 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.80029377 |
| 17 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.76518217 |
| 18 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.74114815 |
| 19 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.74114815 |
| 20 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.73930188 |
| 21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.67046150 |
| 22 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.66412810 |
| 23 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.64001766 |
| 24 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.61816315 |
| 25 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.59816157 |
| 26 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.58681115 |
| 27 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.56423217 |
| 28 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.54806614 |
| 29 | VDR_22108803_ChIP-Seq_LS180_Human | 1.53735272 |
| 30 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.52493985 |
| 31 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.50325127 |
| 32 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.48385940 |
| 33 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.46802164 |
| 34 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.46115361 |
| 35 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.45683064 |
| 36 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.43590860 |
| 37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.43418871 |
| 38 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.42378014 |
| 39 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.41236942 |
| 40 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.40709715 |
| 41 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.37161449 |
| 42 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.35111495 |
| 43 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.33164387 |
| 44 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.32486263 |
| 45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.31382940 |
| 46 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.31086120 |
| 47 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.29420710 |
| 48 | ERA_21632823_ChIP-Seq_H3396_Human | 1.27592366 |
| 49 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.25706907 |
| 50 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.25477050 |
| 51 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.24828339 |
| 52 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.18755967 |
| 53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.18158355 |
| 54 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.16657783 |
| 55 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.15890296 |
| 56 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.14840181 |
| 57 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.14718245 |
| 58 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.14528489 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.14207239 |
| 60 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.10209543 |
| 61 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.09735662 |
| 62 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.08861793 |
| 63 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.08789842 |
| 64 | OCT4_19829295_ChIP-Seq_ESCs_Human | 1.08327240 |
| 65 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.05974516 |
| 66 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.05487288 |
| 67 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.04161229 |
| 68 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.01890212 |
| 69 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.01532097 |
| 70 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.00964420 |
| 71 | P68_20966046_ChIP-Seq_HELA_Human | 1.00440446 |
| 72 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.99197016 |
| 73 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.98523640 |
| 74 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.97989094 |
| 75 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.97978952 |
| 76 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.97310022 |
| 77 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.96898496 |
| 78 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.95602058 |
| 79 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.95488491 |
| 80 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.94252248 |
| 81 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.93828381 |
| 82 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.93062679 |
| 83 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.92829090 |
| 84 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.91820573 |
| 85 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.91720886 |
| 86 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.91173767 |
| 87 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.91120955 |
| 88 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.90420328 |
| 89 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.90061067 |
| 90 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.90054083 |
| 91 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.89831468 |
| 92 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.89311982 |
| 93 | SA1_27219007_Chip-Seq_Bcells_Human | 0.89243490 |
| 94 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89066366 |
| 95 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.88113733 |
| 96 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.87912824 |
| 97 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.86317642 |
| 98 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.85166266 |
| 99 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.84955743 |
| 100 | NCOR_22424771_ChIP-Seq_293T_Human | 0.84615846 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.93525533 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.98434771 |
| 3 | MP0003122_maternal_imprinting | 3.82070444 |
| 4 | MP0003787_abnormal_imprinting | 3.61752993 |
| 5 | MP0003123_paternal_imprinting | 2.94117470 |
| 6 | MP0003121_genomic_imprinting | 2.77471747 |
| 7 | MP0002653_abnormal_ependyma_morphology | 2.72021852 |
| 8 | MP0008789_abnormal_olfactory_epithelium | 2.68584811 |
| 9 | MP0004142_abnormal_muscle_tone | 2.42989121 |
| 10 | MP0005394_taste/olfaction_phenotype | 2.41634799 |
| 11 | MP0005499_abnormal_olfactory_system | 2.41634799 |
| 12 | MP0008877_abnormal_DNA_methylation | 2.35604885 |
| 13 | MP0000778_abnormal_nervous_system | 2.19590904 |
| 14 | MP0003646_muscle_fatigue | 2.09449888 |
| 15 | MP0003136_yellow_coat_color | 2.09079009 |
| 16 | MP0003878_abnormal_ear_physiology | 2.07657055 |
| 17 | MP0005377_hearing/vestibular/ear_phenot | 2.07657055 |
| 18 | MP0001485_abnormal_pinna_reflex | 2.07002382 |
| 19 | MP0003879_abnormal_hair_cell | 1.90832664 |
| 20 | MP0000049_abnormal_middle_ear | 1.90052643 |
| 21 | MP0006276_abnormal_autonomic_nervous | 1.84003908 |
| 22 | MP0002163_abnormal_gland_morphology | 1.83270338 |
| 23 | MP0001293_anophthalmia | 1.72929786 |
| 24 | MP0004885_abnormal_endolymph | 1.70046867 |
| 25 | MP0000566_synostosis | 1.68773333 |
| 26 | MP0004742_abnormal_vestibular_system | 1.62269062 |
| 27 | MP0010030_abnormal_orbit_morphology | 1.51948073 |
| 28 | MP0001968_abnormal_touch/_nociception | 1.44987401 |
| 29 | MP0001529_abnormal_vocalization | 1.44483528 |
| 30 | MP0002063_abnormal_learning/memory/cond | 1.38163293 |
| 31 | MP0002557_abnormal_social/conspecific_i | 1.37437700 |
| 32 | MP0000955_abnormal_spinal_cord | 1.37028105 |
| 33 | MP0005551_abnormal_eye_electrophysiolog | 1.34644900 |
| 34 | MP0003635_abnormal_synaptic_transmissio | 1.34549527 |
| 35 | MP0001970_abnormal_pain_threshold | 1.34466493 |
| 36 | MP0002272_abnormal_nervous_system | 1.33844122 |
| 37 | MP0002733_abnormal_thermal_nociception | 1.29442700 |
| 38 | MP0009745_abnormal_behavioral_response | 1.28823350 |
| 39 | MP0002638_abnormal_pupillary_reflex | 1.27943862 |
| 40 | MP0002160_abnormal_reproductive_system | 1.22519405 |
| 41 | MP0003942_abnormal_urinary_system | 1.22513724 |
| 42 | MP0004133_heterotaxia | 1.22139582 |
| 43 | MP0000631_abnormal_neuroendocrine_gland | 1.20685495 |
| 44 | MP0004859_abnormal_synaptic_plasticity | 1.20236128 |
| 45 | MP0000026_abnormal_inner_ear | 1.20178414 |
| 46 | MP0002184_abnormal_innervation | 1.20068997 |
| 47 | MP0003880_abnormal_central_pattern | 1.19772018 |
| 48 | MP0005389_reproductive_system_phenotype | 1.18873658 |
| 49 | MP0005423_abnormal_somatic_nervous | 1.18861200 |
| 50 | MP0001984_abnormal_olfaction | 1.18335010 |
| 51 | MP0005195_abnormal_posterior_eye | 1.17587663 |
| 52 | MP0002735_abnormal_chemical_nociception | 1.16550294 |
| 53 | MP0002572_abnormal_emotion/affect_behav | 1.15626937 |
| 54 | MP0002734_abnormal_mechanical_nocicepti | 1.15596027 |
| 55 | MP0001440_abnormal_grooming_behavior | 1.15083179 |
| 56 | MP0001348_abnormal_lacrimal_gland | 1.13685797 |
| 57 | MP0002752_abnormal_somatic_nervous | 1.12570420 |
| 58 | MP0002938_white_spotting | 1.11851808 |
| 59 | MP0001986_abnormal_taste_sensitivity | 1.11563231 |
| 60 | MP0001919_abnormal_reproductive_system | 1.11355909 |
| 61 | MP0002095_abnormal_skin_pigmentation | 1.07086765 |
| 62 | MP0009046_muscle_twitch | 1.04518694 |
| 63 | MP0004145_abnormal_muscle_electrophysio | 1.03793473 |
| 64 | MP0002736_abnormal_nociception_after | 1.03451441 |
| 65 | MP0002067_abnormal_sensory_capabilities | 1.02067214 |
| 66 | MP0002882_abnormal_neuron_morphology | 1.01252901 |
| 67 | MP0001486_abnormal_startle_reflex | 1.01147808 |
| 68 | MP0001188_hyperpigmentation | 1.00721517 |
| 69 | MP0002233_abnormal_nose_morphology | 1.00268298 |
| 70 | MP0002064_seizures | 0.99891317 |
| 71 | MP0001905_abnormal_dopamine_level | 0.99669581 |
| 72 | MP0002152_abnormal_brain_morphology | 0.97935193 |
| 73 | MP0001963_abnormal_hearing_physiology | 0.96405279 |
| 74 | MP0005645_abnormal_hypothalamus_physiol | 0.95071725 |
| 75 | MP0005174_abnormal_tail_pigmentation | 0.94950655 |
| 76 | MP0002249_abnormal_larynx_morphology | 0.94390856 |
| 77 | MP0008872_abnormal_physiological_respon | 0.93483150 |
| 78 | MP0002876_abnormal_thyroid_physiology | 0.93170957 |
| 79 | MP0003755_abnormal_palate_morphology | 0.92440284 |
| 80 | MP0003937_abnormal_limbs/digits/tail_de | 0.92141094 |
| 81 | MP0004130_abnormal_muscle_cell | 0.91326251 |
| 82 | MP0003938_abnormal_ear_development | 0.90238910 |
| 83 | MP0005379_endocrine/exocrine_gland_phen | 0.87186942 |
| 84 | MP0003861_abnormal_nervous_system | 0.86449638 |
| 85 | MP0005084_abnormal_gallbladder_morpholo | 0.83481553 |
| 86 | MP0001502_abnormal_circadian_rhythm | 0.82639809 |
| 87 | MP0006072_abnormal_retinal_apoptosis | 0.81968471 |
| 88 | MP0009053_abnormal_anal_canal | 0.81441099 |
| 89 | MP0002837_dystrophic_cardiac_calcinosis | 0.80995167 |
| 90 | MP0001286_abnormal_eye_development | 0.80683586 |
| 91 | MP0001324_abnormal_eye_pigmentation | 0.79935737 |
| 92 | MP0008775_abnormal_heart_ventricle | 0.77702439 |
| 93 | MP0002102_abnormal_ear_morphology | 0.77463337 |
| 94 | MP0005391_vision/eye_phenotype | 0.77094312 |
| 95 | MP0003890_abnormal_embryonic-extraembry | 0.75757163 |
| 96 | MP0005646_abnormal_pituitary_gland | 0.74978525 |
| 97 | MP0002234_abnormal_pharynx_morphology | 0.74250561 |
| 98 | MP0002092_abnormal_eye_morphology | 0.72841673 |
| 99 | MP0004811_abnormal_neuron_physiology | 0.71618564 |
| 100 | MP0003186_abnormal_redox_activity | 0.70801647 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 7.22903837 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.70931027 |
| 3 | Abnormality of midbrain morphology (HP:0002418) | 4.09123876 |
| 4 | Molar tooth sign on MRI (HP:0002419) | 4.09123876 |
| 5 | Macrocytic anemia (HP:0001972) | 3.83537913 |
| 6 | Septo-optic dysplasia (HP:0100842) | 3.66324034 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.62264120 |
| 8 | Pancreatic fibrosis (HP:0100732) | 3.50376430 |
| 9 | Pallor (HP:0000980) | 3.27530221 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.24788796 |
| 11 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.22019943 |
| 12 | Myokymia (HP:0002411) | 3.18148814 |
| 13 | Acute encephalopathy (HP:0006846) | 3.16564463 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 2.96473606 |
| 15 | Absent thumb (HP:0009777) | 2.92449767 |
| 16 | Stenosis of the external auditory canal (HP:0000402) | 2.91655884 |
| 17 | Rib fusion (HP:0000902) | 2.90760079 |
| 18 | Polyphagia (HP:0002591) | 2.74115499 |
| 19 | Progressive macrocephaly (HP:0004481) | 2.73659928 |
| 20 | Medial flaring of the eyebrow (HP:0010747) | 2.71850396 |
| 21 | Agitation (HP:0000713) | 2.71113799 |
| 22 | Pancreatic cysts (HP:0001737) | 2.68550094 |
| 23 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.62645521 |
| 24 | Absent/shortened dynein arms (HP:0200106) | 2.62645521 |
| 25 | Partial duplication of thumb phalanx (HP:0009944) | 2.62188068 |
| 26 | Abnormality of the diencephalon (HP:0010662) | 2.59978186 |
| 27 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.57892146 |
| 28 | 3-Methylglutaconic aciduria (HP:0003535) | 2.55661930 |
| 29 | Abnormality of the labia minora (HP:0012880) | 2.55042331 |
| 30 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.54124082 |
| 31 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.53441139 |
| 32 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.53441139 |
| 33 | Abnormal ciliary motility (HP:0012262) | 2.52356071 |
| 34 | Nephronophthisis (HP:0000090) | 2.50272834 |
| 35 | Gait imbalance (HP:0002141) | 2.50264955 |
| 36 | Mitochondrial inheritance (HP:0001427) | 2.48178794 |
| 37 | Asplenia (HP:0001746) | 2.47571559 |
| 38 | True hermaphroditism (HP:0010459) | 2.46026331 |
| 39 | Depressed nasal ridge (HP:0000457) | 2.45355997 |
| 40 | Sclerocornea (HP:0000647) | 2.42970325 |
| 41 | Pendular nystagmus (HP:0012043) | 2.42847314 |
| 42 | Abnormal hemoglobin (HP:0011902) | 2.40019398 |
| 43 | Pachygyria (HP:0001302) | 2.39509507 |
| 44 | Colon cancer (HP:0003003) | 2.35758526 |
| 45 | Congenital stationary night blindness (HP:0007642) | 2.33423156 |
| 46 | Anophthalmia (HP:0000528) | 2.32256244 |
| 47 | Hyperthyroidism (HP:0000836) | 2.31751396 |
| 48 | Supernumerary spleens (HP:0009799) | 2.29739823 |
| 49 | Anencephaly (HP:0002323) | 2.29522000 |
| 50 | Cystic liver disease (HP:0006706) | 2.25261807 |
| 51 | Hyperglycinemia (HP:0002154) | 2.24130660 |
| 52 | Type II lissencephaly (HP:0007260) | 2.23020766 |
| 53 | Abnormality of reticulocytes (HP:0004312) | 2.20984967 |
| 54 | Increased CSF lactate (HP:0002490) | 2.20778355 |
| 55 | Maternal diabetes (HP:0009800) | 2.18845313 |
| 56 | Partial duplication of the phalanx of hand (HP:0009999) | 2.17690828 |
| 57 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.16543922 |
| 58 | Congenital primary aphakia (HP:0007707) | 2.16253148 |
| 59 | Elfin facies (HP:0004428) | 2.16251011 |
| 60 | Optic disc pallor (HP:0000543) | 2.14711754 |
| 61 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.14401071 |
| 62 | Renovascular hypertension (HP:0100817) | 2.12841932 |
| 63 | Chronic hepatic failure (HP:0100626) | 2.12186192 |
| 64 | Absent septum pellucidum (HP:0001331) | 2.11916976 |
| 65 | 11 pairs of ribs (HP:0000878) | 2.11824428 |
| 66 | Tubular atrophy (HP:0000092) | 2.08675802 |
| 67 | Cerebral edema (HP:0002181) | 2.05781328 |
| 68 | Failure to thrive in infancy (HP:0001531) | 2.03946540 |
| 69 | Hypoplasia of the radius (HP:0002984) | 2.02877042 |
| 70 | Nephrogenic diabetes insipidus (HP:0009806) | 2.02395251 |
| 71 | Abnormal eating behavior (HP:0100738) | 2.01558790 |
| 72 | Papilledema (HP:0001085) | 2.01181791 |
| 73 | Optic nerve hypoplasia (HP:0000609) | 2.01144826 |
| 74 | Impulsivity (HP:0100710) | 2.00845129 |
| 75 | Lissencephaly (HP:0001339) | 2.00830087 |
| 76 | Postaxial foot polydactyly (HP:0001830) | 1.98641937 |
| 77 | Hip dysplasia (HP:0001385) | 1.97659545 |
| 78 | Abnormality of the renal medulla (HP:0100957) | 1.97426096 |
| 79 | Growth hormone deficiency (HP:0000824) | 1.95404436 |
| 80 | Ectopic kidney (HP:0000086) | 1.95029746 |
| 81 | Deep palmar crease (HP:0006191) | 1.92168264 |
| 82 | Abnormality of DNA repair (HP:0003254) | 1.91903919 |
| 83 | Narrow forehead (HP:0000341) | 1.91824443 |
| 84 | Overriding aorta (HP:0002623) | 1.90952616 |
| 85 | Oligodactyly (hands) (HP:0001180) | 1.90326975 |
| 86 | Bifid tongue (HP:0010297) | 1.90181349 |
| 87 | Renal duplication (HP:0000075) | 1.88927679 |
| 88 | Hypoplasia of the brainstem (HP:0002365) | 1.85355199 |
| 89 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.85355199 |
| 90 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.84208398 |
| 91 | Vaginal atresia (HP:0000148) | 1.83369096 |
| 92 | Bile duct proliferation (HP:0001408) | 1.81131428 |
| 93 | Abnormal biliary tract physiology (HP:0012439) | 1.81131428 |
| 94 | Oligodactyly (HP:0012165) | 1.80654790 |
| 95 | Abnormality of the aortic arch (HP:0012303) | 1.79526444 |
| 96 | Hepatocellular necrosis (HP:0001404) | 1.78508749 |
| 97 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.78267146 |
| 98 | Polydipsia (HP:0001959) | 1.74889036 |
| 99 | Abnormal drinking behavior (HP:0030082) | 1.74889036 |
| 100 | Genital tract atresia (HP:0001827) | 1.74545461 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 3.48286953 |
| 2 | STK16 | 3.28704900 |
| 3 | EPHB2 | 3.11780345 |
| 4 | DYRK2 | 2.90120897 |
| 5 | LIMK1 | 2.44319635 |
| 6 | WNK3 | 2.36839598 |
| 7 | MAP3K11 | 2.30101782 |
| 8 | LRRK2 | 2.20909142 |
| 9 | CASK | 2.20599702 |
| 10 | CDK19 | 2.11148088 |
| 11 | MARK1 | 2.07178314 |
| 12 | CAMKK2 | 1.99900525 |
| 13 | SIK2 | 1.94834311 |
| 14 | NTRK2 | 1.85390008 |
| 15 | PIK3CA | 1.84589391 |
| 16 | ADRBK2 | 1.80585796 |
| 17 | PINK1 | 1.70662302 |
| 18 | GRK1 | 1.69825927 |
| 19 | MAP2K7 | 1.66977569 |
| 20 | TYRO3 | 1.66848099 |
| 21 | CAMKK1 | 1.52343705 |
| 22 | EPHA4 | 1.40863281 |
| 23 | CAMK1 | 1.40852458 |
| 24 | PRKCG | 1.40281591 |
| 25 | DYRK1B | 1.38544054 |
| 26 | BCKDK | 1.37192756 |
| 27 | CAMK1D | 1.31474643 |
| 28 | STK39 | 1.29157751 |
| 29 | NEK2 | 1.27632433 |
| 30 | TIE1 | 1.27428235 |
| 31 | MINK1 | 1.26591046 |
| 32 | CDC7 | 1.21176580 |
| 33 | BRSK1 | 1.20172325 |
| 34 | CDC42BPA | 1.19792241 |
| 35 | NUAK1 | 1.15412748 |
| 36 | MAP4K2 | 1.14601897 |
| 37 | MAPK13 | 1.11729024 |
| 38 | PRKCH | 1.09669071 |
| 39 | WNK1 | 1.08819892 |
| 40 | STK11 | 1.08454389 |
| 41 | AURKA | 1.06252893 |
| 42 | MARK2 | 1.03769226 |
| 43 | MAP3K9 | 1.02245199 |
| 44 | BRAF | 1.00160974 |
| 45 | SGK223 | 0.96011431 |
| 46 | SGK494 | 0.96011431 |
| 47 | ABL2 | 0.95274928 |
| 48 | PAK3 | 0.93422090 |
| 49 | TLK1 | 0.93081155 |
| 50 | PDK2 | 0.90314001 |
| 51 | MAP3K4 | 0.88079083 |
| 52 | CAMK1G | 0.87583563 |
| 53 | PIM2 | 0.85606823 |
| 54 | PRKCZ | 0.85451146 |
| 55 | DAPK3 | 0.78394918 |
| 56 | FRK | 0.78002891 |
| 57 | CSNK1E | 0.76425422 |
| 58 | ADRBK1 | 0.74029428 |
| 59 | PHKG1 | 0.73691265 |
| 60 | PHKG2 | 0.73691265 |
| 61 | CDK8 | 0.71878747 |
| 62 | DMPK | 0.70926918 |
| 63 | TNIK | 0.70125009 |
| 64 | PRKACA | 0.69666403 |
| 65 | SGK1 | 0.68672102 |
| 66 | CSNK2A2 | 0.68633430 |
| 67 | CAMK4 | 0.64081634 |
| 68 | NTRK1 | 0.63806296 |
| 69 | PRKCQ | 0.62835921 |
| 70 | CDK14 | 0.62370097 |
| 71 | RPS6KA6 | 0.60743749 |
| 72 | PRKCI | 0.59937699 |
| 73 | NME1 | 0.59024665 |
| 74 | CDK5 | 0.56595075 |
| 75 | DYRK1A | 0.55323766 |
| 76 | PRKD3 | 0.53317956 |
| 77 | CDK11A | 0.53203192 |
| 78 | BMPR1B | 0.53086015 |
| 79 | TXK | 0.51632493 |
| 80 | PAK6 | 0.50743699 |
| 81 | RPS6KA2 | 0.49477261 |
| 82 | MAP2K4 | 0.48017467 |
| 83 | OXSR1 | 0.47846779 |
| 84 | INSRR | 0.46612076 |
| 85 | ICK | 0.46577830 |
| 86 | MAPK15 | 0.45628594 |
| 87 | RPS6KL1 | 0.45615773 |
| 88 | RPS6KC1 | 0.45615773 |
| 89 | NME2 | 0.45301994 |
| 90 | CSNK1G2 | 0.44698953 |
| 91 | CDK15 | 0.44617831 |
| 92 | PLK1 | 0.44244304 |
| 93 | AURKB | 0.43174877 |
| 94 | CAMK2A | 0.43020138 |
| 95 | AKT1 | 0.42722692 |
| 96 | DYRK3 | 0.41862548 |
| 97 | GRK7 | 0.41170932 |
| 98 | ARAF | 0.40922968 |
| 99 | PRKCA | 0.40814405 |
| 100 | RPS6KA3 | 0.40801318 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.10507673 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.08401656 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46527094 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.37487673 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.70377216 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.65372963 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.62674128 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.43742655 |
| 9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.29367335 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.08304595 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.96137051 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.90438209 |
| 13 | Nicotine addiction_Homo sapiens_hsa05033 | 1.88095960 |
| 14 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.87535270 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.71454593 |
| 16 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.42766111 |
| 17 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.41313414 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.32287434 |
| 19 | RNA polymerase_Homo sapiens_hsa03020 | 1.29423581 |
| 20 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.28987466 |
| 21 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.24962993 |
| 22 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.20086956 |
| 23 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.19407640 |
| 24 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.17192613 |
| 25 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.16526659 |
| 26 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.15491991 |
| 27 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.11279617 |
| 28 | Morphine addiction_Homo sapiens_hsa05032 | 1.09642402 |
| 29 | Peroxisome_Homo sapiens_hsa04146 | 1.07811938 |
| 30 | RNA degradation_Homo sapiens_hsa03018 | 1.02119651 |
| 31 | Axon guidance_Homo sapiens_hsa04360 | 0.99842710 |
| 32 | Insulin secretion_Homo sapiens_hsa04911 | 0.99558495 |
| 33 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.98253161 |
| 34 | Homologous recombination_Homo sapiens_hsa03440 | 0.95544207 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.95329793 |
| 36 | Protein export_Homo sapiens_hsa03060 | 0.94217823 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.93029939 |
| 38 | Basal transcription factors_Homo sapiens_hsa03022 | 0.90950017 |
| 39 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.89175142 |
| 40 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.88802776 |
| 41 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.88066049 |
| 42 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.84638187 |
| 43 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.83987696 |
| 44 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.83019277 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.79906592 |
| 46 | GABAergic synapse_Homo sapiens_hsa04727 | 0.79824106 |
| 47 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.79619738 |
| 48 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.78933831 |
| 49 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.75046678 |
| 50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.73985620 |
| 51 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.73561434 |
| 52 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72605847 |
| 53 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.70196925 |
| 54 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.70140004 |
| 55 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.69828879 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.68896260 |
| 57 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65882051 |
| 58 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.65264190 |
| 59 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.64820296 |
| 60 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.61723681 |
| 61 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.61365654 |
| 62 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.60558264 |
| 63 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.60474190 |
| 64 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.58116617 |
| 65 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.57575864 |
| 66 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.55226468 |
| 67 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.55062954 |
| 68 | Circadian entrainment_Homo sapiens_hsa04713 | 0.53608346 |
| 69 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.52167073 |
| 70 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.52062882 |
| 71 | Retinol metabolism_Homo sapiens_hsa00830 | 0.51507126 |
| 72 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.50834092 |
| 73 | Taste transduction_Homo sapiens_hsa04742 | 0.48906262 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48668729 |
| 75 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.45697006 |
| 76 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.45547457 |
| 77 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.44971643 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.42800023 |
| 79 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.41226863 |
| 80 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.40880692 |
| 81 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.39789310 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38946690 |
| 83 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.38876691 |
| 84 | Salivary secretion_Homo sapiens_hsa04970 | 0.37723589 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.37133127 |
| 86 | Cocaine addiction_Homo sapiens_hsa05030 | 0.36698349 |
| 87 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.36541456 |
| 88 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.35288567 |
| 89 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.34985362 |
| 90 | Mismatch repair_Homo sapiens_hsa03430 | 0.32206837 |
| 91 | Melanogenesis_Homo sapiens_hsa04916 | 0.32088740 |
| 92 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.30580350 |
| 93 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.30011328 |
| 94 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.28284669 |
| 95 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.27735685 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27698746 |
| 97 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.27017272 |
| 98 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.26632745 |
| 99 | Bile secretion_Homo sapiens_hsa04976 | 0.26403737 |
| 100 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.26276963 |

