Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 7.66584974 |
2 | * viral transcription (GO:0019083) | 7.50946780 |
3 | * translational termination (GO:0006415) | 7.24175946 |
4 | ribosomal small subunit biogenesis (GO:0042274) | 6.67499011 |
5 | * translational elongation (GO:0006414) | 6.36683380 |
6 | maturation of SSU-rRNA (GO:0030490) | 6.26850413 |
7 | * SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.12039922 |
8 | * protein targeting to ER (GO:0045047) | 5.97804423 |
9 | * cotranslational protein targeting to membrane (GO:0006613) | 5.97269285 |
10 | * nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.81627001 |
11 | * establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.69789714 |
12 | * translational initiation (GO:0006413) | 5.68406249 |
13 | * viral life cycle (GO:0019058) | 5.64175631 |
14 | * cellular protein complex disassembly (GO:0043624) | 5.60085944 |
15 | * protein localization to endoplasmic reticulum (GO:0070972) | 5.59616831 |
16 | ribosomal large subunit biogenesis (GO:0042273) | 5.15447270 |
17 | * protein complex disassembly (GO:0043241) | 5.02078141 |
18 | * macromolecular complex disassembly (GO:0032984) | 4.68472610 |
19 | DNA deamination (GO:0045006) | 4.68375495 |
20 | formation of translation preinitiation complex (GO:0001731) | 4.64205853 |
21 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.37737390 |
22 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.36217756 |
23 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.33546460 |
24 | * nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.33073084 |
25 | * translation (GO:0006412) | 4.12929946 |
26 | DNA strand elongation (GO:0022616) | 4.12271885 |
27 | * mRNA catabolic process (GO:0006402) | 4.10895020 |
28 | DNA unwinding involved in DNA replication (GO:0006268) | 4.09337328 |
29 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.08574328 |
30 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.06556485 |
31 | ATP synthesis coupled proton transport (GO:0015986) | 4.06556485 |
32 | * RNA catabolic process (GO:0006401) | 3.93505920 |
33 | * protein targeting to membrane (GO:0006612) | 3.93193244 |
34 | DNA replication initiation (GO:0006270) | 3.86136595 |
35 | rRNA processing (GO:0006364) | 3.65543645 |
36 | rRNA metabolic process (GO:0016072) | 3.52648795 |
37 | telomere maintenance via recombination (GO:0000722) | 3.49598091 |
38 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.44859190 |
39 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.44568523 |
40 | nucleobase biosynthetic process (GO:0046112) | 3.39006664 |
41 | regulation of mitochondrial translation (GO:0070129) | 3.31514393 |
42 | ribosome biogenesis (GO:0042254) | 3.28420223 |
43 | mitotic recombination (GO:0006312) | 3.25607795 |
44 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.24540241 |
45 | negative regulation of RNA splicing (GO:0033119) | 3.23411938 |
46 | telomere maintenance via telomere lengthening (GO:0010833) | 3.21700499 |
47 | cellular component biogenesis (GO:0044085) | 3.20044604 |
48 | protein localization to kinetochore (GO:0034501) | 3.18623139 |
49 | spliceosomal snRNP assembly (GO:0000387) | 3.16800994 |
50 | establishment of integrated proviral latency (GO:0075713) | 3.15331812 |
51 | chaperone-mediated protein transport (GO:0072321) | 3.14167069 |
52 | * protein localization to membrane (GO:0072657) | 3.13666870 |
53 | IMP biosynthetic process (GO:0006188) | 3.11486703 |
54 | DNA replication checkpoint (GO:0000076) | 3.11072049 |
55 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.11026259 |
56 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.10160084 |
57 | ribosome assembly (GO:0042255) | 3.09376092 |
58 | pseudouridine synthesis (GO:0001522) | 3.07544590 |
59 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.06725843 |
60 | UTP biosynthetic process (GO:0006228) | 3.05831485 |
61 | oxidative phosphorylation (GO:0006119) | 3.05652156 |
62 | respiratory electron transport chain (GO:0022904) | 3.05570241 |
63 | mitotic nuclear envelope disassembly (GO:0007077) | 3.00847582 |
64 | regulation of translational fidelity (GO:0006450) | 2.99602702 |
65 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.99493176 |
66 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.98391528 |
67 | purine nucleobase biosynthetic process (GO:0009113) | 2.96181703 |
68 | electron transport chain (GO:0022900) | 2.96033872 |
69 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.95248588 |
70 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.95248588 |
71 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.94506442 |
72 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.93009949 |
73 | GDP-mannose metabolic process (GO:0019673) | 2.91742803 |
74 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.90524025 |
75 | ncRNA 3-end processing (GO:0043628) | 2.84923163 |
76 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.84495831 |
77 | protein targeting to mitochondrion (GO:0006626) | 2.84312656 |
78 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.80415200 |
79 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.79341712 |
80 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.79316353 |
81 | GTP biosynthetic process (GO:0006183) | 2.79101681 |
82 | deoxyribonucleotide catabolic process (GO:0009264) | 2.79100804 |
83 | protein localization to chromosome, centromeric region (GO:0071459) | 2.78567025 |
84 | IMP metabolic process (GO:0046040) | 2.78526687 |
85 | proteasome assembly (GO:0043248) | 2.78367875 |
86 | rRNA transcription (GO:0009303) | 2.78361021 |
87 | base-excision repair, AP site formation (GO:0006285) | 2.77542625 |
88 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.76783456 |
89 | UTP metabolic process (GO:0046051) | 2.75467697 |
90 | spliceosomal complex assembly (GO:0000245) | 2.75403708 |
91 | deoxyribose phosphate catabolic process (GO:0046386) | 2.74321483 |
92 | membrane disassembly (GO:0030397) | 2.73745819 |
93 | nuclear envelope disassembly (GO:0051081) | 2.73745819 |
94 | CENP-A containing nucleosome assembly (GO:0034080) | 2.73132031 |
95 | mRNA splicing, via spliceosome (GO:0000398) | 2.72269090 |
96 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.72269090 |
97 | chromatin remodeling at centromere (GO:0031055) | 2.71656338 |
98 | RNA splicing, via transesterification reactions (GO:0000375) | 2.71270306 |
99 | establishment of protein localization to mitochondrion (GO:0072655) | 2.68919392 |
100 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.67475964 |
101 | * establishment of protein localization to membrane (GO:0090150) | 2.66678990 |
102 | pentose metabolic process (GO:0019321) | 2.66545348 |
103 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.65229514 |
104 | negative regulation of B cell apoptotic process (GO:0002903) | 2.64223888 |
105 | ncRNA processing (GO:0034470) | 2.63832989 |
106 | inner mitochondrial membrane organization (GO:0007007) | 2.63634901 |
107 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.62893167 |
108 | regulation of protein heterodimerization activity (GO:0043497) | 2.62497597 |
109 | DNA replication-independent nucleosome organization (GO:0034724) | 2.62416191 |
110 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.62416191 |
111 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.62198037 |
112 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.61899375 |
113 | termination of RNA polymerase II transcription (GO:0006369) | 2.61744484 |
114 | histone arginine methylation (GO:0034969) | 2.61396158 |
115 | negative regulation of ligase activity (GO:0051352) | 2.60676274 |
116 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.60676274 |
117 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.60017504 |
118 | CTP biosynthetic process (GO:0006241) | 2.58888542 |
119 | CTP metabolic process (GO:0046036) | 2.58888542 |
120 | termination of RNA polymerase III transcription (GO:0006386) | 2.58628402 |
121 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.58628402 |
122 | mitotic metaphase plate congression (GO:0007080) | 2.58371331 |
123 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.58338569 |
124 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.56562950 |
125 | * establishment of protein localization to organelle (GO:0072594) | 2.56490599 |
126 | * gene expression (GO:0010467) | 2.53497309 |
127 | ribonucleoprotein complex assembly (GO:0022618) | 2.52386172 |
128 | proline biosynthetic process (GO:0006561) | 2.52363547 |
129 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.52131876 |
130 | DNA duplex unwinding (GO:0032508) | 2.51853196 |
131 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.51434619 |
132 | * cellular component disassembly (GO:0022411) | 2.50958132 |
133 | ncRNA metabolic process (GO:0034660) | 2.50912088 |
134 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.50344140 |
135 | GMP metabolic process (GO:0046037) | 2.49230411 |
136 | DNA geometric change (GO:0032392) | 2.49127764 |
137 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.48544808 |
138 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.48544808 |
139 | rRNA modification (GO:0000154) | 2.48506358 |
140 | negative regulation of mRNA processing (GO:0050686) | 2.48485178 |
141 | * protein targeting (GO:0006605) | 2.46873970 |
142 | viral mRNA export from host cell nucleus (GO:0046784) | 2.46702122 |
143 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.46525451 |
144 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.46525451 |
145 | * protein localization to organelle (GO:0033365) | 2.46495223 |
146 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.44923397 |
147 | protein localization to mitochondrion (GO:0070585) | 2.44179279 |
148 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.43994730 |
149 | viral protein processing (GO:0019082) | 2.43993323 |
150 | base-excision repair (GO:0006284) | 2.42649377 |
151 | myeloid cell homeostasis (GO:0002262) | 2.42568968 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.73691289 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.33575363 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 4.05145736 |
4 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.14336668 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.92859693 |
6 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.80250549 |
7 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.80047402 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.78201252 |
9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.74288127 |
10 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.68343559 |
11 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.66904576 |
12 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.66680667 |
13 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.56711773 |
14 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.51189267 |
15 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.49729709 |
16 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.45688011 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.32810125 |
18 | * CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.31820976 |
19 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.14957963 |
20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.13660317 |
21 | MYC_22102868_ChIP-Seq_BL_Human | 2.13182045 |
22 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.10688113 |
23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.09104831 |
24 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.02992124 |
25 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.00058897 |
26 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.99767787 |
27 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.91127382 |
28 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.87633816 |
29 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.85482214 |
30 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84772851 |
31 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.72864165 |
32 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.72840685 |
33 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.72626012 |
34 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.70140729 |
35 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.68024759 |
36 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.63337005 |
37 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.59311388 |
38 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.59166523 |
39 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.54271367 |
40 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.53616650 |
41 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.52951647 |
42 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.52219119 |
43 | * FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51798397 |
44 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.51620310 |
45 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.48432146 |
46 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.47969001 |
47 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.47781696 |
48 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.45795719 |
49 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.42555397 |
50 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.41234689 |
51 | * YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.39533946 |
52 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39114507 |
53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38964013 |
54 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.36925109 |
55 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.36806088 |
56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.36146198 |
57 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.35960038 |
58 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.35792249 |
59 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.35538564 |
60 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.35152021 |
61 | * TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32882730 |
62 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.32558640 |
63 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.30803446 |
64 | P68_20966046_ChIP-Seq_HELA_Human | 1.27906648 |
65 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.27801579 |
66 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.27329614 |
67 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.27016617 |
68 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.26686466 |
69 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.25934388 |
70 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.23490534 |
71 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.22463131 |
72 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.21055502 |
73 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.20475627 |
74 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.18887356 |
75 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.18840183 |
76 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.16842574 |
77 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.16416555 |
78 | * DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.16344343 |
79 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.16228778 |
80 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.16121566 |
81 | * FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.13624614 |
82 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.13205863 |
83 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.12522772 |
84 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.12238218 |
85 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11326773 |
86 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.10363498 |
87 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.10293686 |
88 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.08415494 |
89 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.08018254 |
90 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.06521239 |
91 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.06325774 |
92 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.04794273 |
93 | * SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.02967926 |
94 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.02083898 |
95 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 1.00497376 |
96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99719979 |
97 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.99556204 |
98 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.99455210 |
99 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.99308343 |
100 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.99028868 |
101 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.98722169 |
102 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.98694930 |
103 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.97989319 |
104 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.97942201 |
105 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.96993222 |
106 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.96569970 |
107 | UTX_26944678_Chip-Seq_JUKART_Human | 0.96256575 |
108 | MAF_26560356_Chip-Seq_TH1_Human | 0.96169566 |
109 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.95627370 |
110 | * CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93941486 |
111 | * RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93677809 |
112 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.93557511 |
113 | MAF_26560356_Chip-Seq_TH2_Human | 0.93293172 |
114 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.93237401 |
115 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.93032725 |
116 | * SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.92846194 |
117 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.92080521 |
118 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.91968111 |
119 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.91950521 |
120 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.91283459 |
121 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.90973256 |
122 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.89487337 |
123 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.87772838 |
124 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.87653042 |
125 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.87370440 |
126 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.86992763 |
127 | * SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.83921449 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.59710923 |
2 | MP0004957_abnormal_blastocyst_morpholog | 3.82470295 |
3 | MP0003111_abnormal_nucleus_morphology | 3.44600334 |
4 | MP0010094_abnormal_chromosome_stability | 3.33982559 |
5 | MP0003077_abnormal_cell_cycle | 3.29572587 |
6 | MP0002396_abnormal_hematopoietic_system | 2.69950236 |
7 | MP0008057_abnormal_DNA_replication | 2.65563637 |
8 | MP0010352_gastrointestinal_tract_polyps | 2.42192584 |
9 | MP0009379_abnormal_foot_pigmentation | 2.38917335 |
10 | MP0008058_abnormal_DNA_repair | 2.34827088 |
11 | MP0008007_abnormal_cellular_replicative | 2.31700718 |
12 | MP0008932_abnormal_embryonic_tissue | 2.10687590 |
13 | MP0000490_abnormal_crypts_of | 2.10528543 |
14 | MP0008995_early_reproductive_senescence | 1.97796760 |
15 | MP0003763_abnormal_thymus_physiology | 1.94252074 |
16 | MP0001730_embryonic_growth_arrest | 1.93806342 |
17 | MP0009333_abnormal_splenocyte_physiolog | 1.89918999 |
18 | MP0000350_abnormal_cell_proliferation | 1.86505462 |
19 | MP0004808_abnormal_hematopoietic_stem | 1.82554358 |
20 | MP0006292_abnormal_olfactory_placode | 1.79080285 |
21 | MP0005397_hematopoietic_system_phenotyp | 1.70055744 |
22 | MP0001545_abnormal_hematopoietic_system | 1.70055744 |
23 | MP0000566_synostosis | 1.62585667 |
24 | MP0003786_premature_aging | 1.59256344 |
25 | MP0002163_abnormal_gland_morphology | 1.56308563 |
26 | MP0003123_paternal_imprinting | 1.55823746 |
27 | MP0002398_abnormal_bone_marrow | 1.50092087 |
28 | MP0006054_spinal_hemorrhage | 1.49151996 |
29 | MP0000685_abnormal_immune_system | 1.49075554 |
30 | MP0002019_abnormal_tumor_incidence | 1.47459678 |
31 | MP0002249_abnormal_larynx_morphology | 1.44804210 |
32 | MP0000703_abnormal_thymus_morphology | 1.44796538 |
33 | MP0002722_abnormal_immune_system | 1.43563360 |
34 | MP0002796_impaired_skin_barrier | 1.43067039 |
35 | MP0000678_abnormal_parathyroid_gland | 1.40417022 |
36 | MP0001697_abnormal_embryo_size | 1.40218030 |
37 | MP0000313_abnormal_cell_death | 1.39394869 |
38 | MP0002080_prenatal_lethality | 1.37822407 |
39 | MP0006035_abnormal_mitochondrial_morpho | 1.36407587 |
40 | MP0004185_abnormal_adipocyte_glucose | 1.36061341 |
41 | MP0002132_abnormal_respiratory_system | 1.34902232 |
42 | MP0000689_abnormal_spleen_morphology | 1.33460956 |
43 | MP0001672_abnormal_embryogenesis/_devel | 1.30471055 |
44 | MP0005380_embryogenesis_phenotype | 1.30471055 |
45 | MP0010307_abnormal_tumor_latency | 1.29367426 |
46 | MP0003567_abnormal_fetal_cardiomyocyte | 1.29122092 |
47 | MP0006036_abnormal_mitochondrial_physio | 1.27005752 |
48 | MP0009278_abnormal_bone_marrow | 1.25485948 |
49 | MP0000858_altered_metastatic_potential | 1.25023015 |
50 | MP0000372_irregular_coat_pigmentation | 1.22499338 |
51 | MP0003806_abnormal_nucleotide_metabolis | 1.22228946 |
52 | MP0001346_abnormal_lacrimal_gland | 1.22000298 |
53 | MP0002085_abnormal_embryonic_tissue | 1.21803759 |
54 | MP0010030_abnormal_orbit_morphology | 1.21682441 |
55 | MP0005451_abnormal_body_composition | 1.21301427 |
56 | MP0002429_abnormal_blood_cell | 1.20196237 |
57 | MP0001835_abnormal_antigen_presentation | 1.20038290 |
58 | MP0003984_embryonic_growth_retardation | 1.19996011 |
59 | MP0002088_abnormal_embryonic_growth/wei | 1.17908879 |
60 | MP0002086_abnormal_extraembryonic_tissu | 1.17066988 |
61 | MP0004197_abnormal_fetal_growth/weight/ | 1.16586456 |
62 | MP0001800_abnormal_humoral_immune | 1.14361238 |
63 | MP0002084_abnormal_developmental_patter | 1.14246055 |
64 | MP0000465_gastrointestinal_hemorrhage | 1.12251959 |
65 | MP0000716_abnormal_immune_system | 1.12243405 |
66 | MP0004858_abnormal_nervous_system | 1.10834143 |
67 | MP0000537_abnormal_urethra_morphology | 1.09927895 |
68 | MP0001853_heart_inflammation | 1.08890262 |
69 | MP0004381_abnormal_hair_follicle | 1.07979201 |
70 | MP0005075_abnormal_melanosome_morpholog | 1.03907576 |
71 | MP0002420_abnormal_adaptive_immunity | 1.03617399 |
72 | MP0005671_abnormal_response_to | 1.03589373 |
73 | MP0002405_respiratory_system_inflammati | 1.03221356 |
74 | MP0005023_abnormal_wound_healing | 1.02530374 |
75 | MP0001819_abnormal_immune_cell | 1.01607141 |
76 | MP0001293_anophthalmia | 1.00979188 |
77 | MP0005174_abnormal_tail_pigmentation | 1.00830731 |
78 | MP0003315_abnormal_perineum_morphology | 0.99347589 |
79 | MP0010155_abnormal_intestine_physiology | 0.99013117 |
80 | MP0002452_abnormal_antigen_presenting | 0.98787071 |
81 | MP0005501_abnormal_skin_physiology | 0.96168811 |
82 | MP0002166_altered_tumor_susceptibility | 0.95634136 |
83 | MP0003866_abnormal_defecation | 0.95430141 |
84 | MP0008260_abnormal_autophagy | 0.95384243 |
85 | MP0002653_abnormal_ependyma_morphology | 0.93380560 |
86 | MP0005058_abnormal_lysosome_morphology | 0.93185902 |
87 | MP0000477_abnormal_intestine_morphology | 0.93015388 |
88 | MP0001873_stomach_inflammation | 0.92501591 |
89 | MP0002723_abnormal_immune_serum | 0.92416937 |
90 | MP0003436_decreased_susceptibility_to | 0.92249946 |
91 | MP0005076_abnormal_cell_differentiation | 0.90419844 |
92 | MP0000049_abnormal_middle_ear | 0.89964291 |
93 | MP0003186_abnormal_redox_activity | 0.89186574 |
94 | MP0000358_abnormal_cell_content/ | 0.88143307 |
95 | MP0005025_abnormal_response_to | 0.88025730 |
96 | MP0002277_abnormal_respiratory_mucosa | 0.86324338 |
97 | MP0001881_abnormal_mammary_gland | 0.85837773 |
98 | MP0004133_heterotaxia | 0.85615472 |
99 | MP0000681_abnormal_thyroid_gland | 0.84736847 |
100 | MP0009785_altered_susceptibility_to | 0.84232809 |
101 | MP0003566_abnormal_cell_adhesion | 0.82446034 |
102 | MP0003941_abnormal_skin_development | 0.81674401 |
103 | MP0005000_abnormal_immune_tolerance | 0.80574185 |
104 | MP0003718_maternal_effect | 0.79989056 |
105 | MP0003705_abnormal_hypodermis_morpholog | 0.79151387 |
106 | MP0002006_tumorigenesis | 0.77930677 |
107 | MP0003119_abnormal_digestive_system | 0.77052227 |
108 | MP0009672_abnormal_birth_weight | 0.76856097 |
109 | MP0001849_ear_inflammation | 0.76552048 |
110 | MP0003938_abnormal_ear_development | 0.76077180 |
111 | MP0002095_abnormal_skin_pigmentation | 0.75929476 |
112 | MP0002111_abnormal_tail_morphology | 0.74742088 |
113 | MP0005666_abnormal_adipose_tissue | 0.67642069 |
114 | MP0005464_abnormal_platelet_physiology | 0.67425915 |
115 | MP0002932_abnormal_joint_morphology | 0.66417432 |
116 | MP0002697_abnormal_eye_size | 0.65596893 |
117 | MP0004947_skin_inflammation | 0.65500421 |
118 | MP0002938_white_spotting | 0.65294693 |
119 | MP0002098_abnormal_vibrissa_morphology | 0.65276025 |
120 | MP0009053_abnormal_anal_canal | 0.65109927 |
121 | MP0002210_abnormal_sex_determination | 0.64682807 |
122 | MP0009931_abnormal_skin_appearance | 0.63194280 |
123 | MP0001915_intracranial_hemorrhage | 0.63133790 |
124 | MP0001145_abnormal_male_reproductive | 0.62945626 |
125 | MP0001216_abnormal_epidermal_layer | 0.62598374 |
126 | MP0005384_cellular_phenotype | 0.60676861 |
127 | MP0000750_abnormal_muscle_regeneration | 0.60664761 |
128 | MP0003448_altered_tumor_morphology | 0.59351070 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 7.68209342 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 7.09991833 |
3 | Reticulocytopenia (HP:0001896) | 6.87364381 |
4 | Macrocytic anemia (HP:0001972) | 4.93118940 |
5 | Pallor (HP:0000980) | 4.76552011 |
6 | Microvesicular hepatic steatosis (HP:0001414) | 4.02517033 |
7 | Colon cancer (HP:0003003) | 3.79590240 |
8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.67739422 |
9 | Aplastic anemia (HP:0001915) | 3.66626491 |
10 | Thrombocytosis (HP:0001894) | 3.64587195 |
11 | Mitochondrial inheritance (HP:0001427) | 3.47723596 |
12 | Hepatocellular necrosis (HP:0001404) | 3.45368767 |
13 | Increased intramyocellular lipid droplets (HP:0012240) | 3.43500274 |
14 | Acute necrotizing encephalopathy (HP:0006965) | 3.41029591 |
15 | Oral leukoplakia (HP:0002745) | 3.30843765 |
16 | Increased muscle lipid content (HP:0009058) | 3.20703128 |
17 | Birth length less than 3rd percentile (HP:0003561) | 3.20536166 |
18 | Selective tooth agenesis (HP:0001592) | 3.17947748 |
19 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.06470042 |
20 | 11 pairs of ribs (HP:0000878) | 3.06008299 |
21 | Hepatic necrosis (HP:0002605) | 3.05285039 |
22 | Increased hepatocellular lipid droplets (HP:0006565) | 3.04221510 |
23 | Acute encephalopathy (HP:0006846) | 3.03123795 |
24 | Increased CSF lactate (HP:0002490) | 2.94544127 |
25 | Respiratory difficulties (HP:0002880) | 2.85945110 |
26 | Absent thumb (HP:0009777) | 2.85895027 |
27 | Multiple enchondromatosis (HP:0005701) | 2.85411982 |
28 | Trismus (HP:0000211) | 2.85299086 |
29 | Broad distal phalanx of finger (HP:0009836) | 2.82350463 |
30 | Abnormality of reticulocytes (HP:0004312) | 2.79988987 |
31 | Breast hypoplasia (HP:0003187) | 2.79273128 |
32 | Lipid accumulation in hepatocytes (HP:0006561) | 2.74533142 |
33 | Rough bone trabeculation (HP:0100670) | 2.70228088 |
34 | IgM deficiency (HP:0002850) | 2.61469658 |
35 | Agammaglobulinemia (HP:0004432) | 2.60726512 |
36 | Microretrognathia (HP:0000308) | 2.60049005 |
37 | Ragged-red muscle fibers (HP:0003200) | 2.51143649 |
38 | Partial duplication of thumb phalanx (HP:0009944) | 2.47930944 |
39 | Basal cell carcinoma (HP:0002671) | 2.45649616 |
40 | Exercise intolerance (HP:0003546) | 2.44312350 |
41 | Carpal bone hypoplasia (HP:0001498) | 2.43261000 |
42 | Medulloblastoma (HP:0002885) | 2.41709568 |
43 | Panhypogammaglobulinemia (HP:0003139) | 2.40777011 |
44 | Seborrheic dermatitis (HP:0001051) | 2.40544534 |
45 | Progressive macrocephaly (HP:0004481) | 2.39331077 |
46 | Renal Fanconi syndrome (HP:0001994) | 2.34933279 |
47 | Cerebral edema (HP:0002181) | 2.33419481 |
48 | Neoplasm of the pancreas (HP:0002894) | 2.33321936 |
49 | Testicular atrophy (HP:0000029) | 2.33261590 |
50 | Ependymoma (HP:0002888) | 2.32034181 |
51 | Lactic acidosis (HP:0003128) | 2.30246041 |
52 | Myelodysplasia (HP:0002863) | 2.29547860 |
53 | Hypertensive crisis (HP:0100735) | 2.29462802 |
54 | Partial duplication of the phalanx of hand (HP:0009999) | 2.28958283 |
55 | Patellar aplasia (HP:0006443) | 2.27774662 |
56 | Petechiae (HP:0000967) | 2.23833871 |
57 | Increased serum lactate (HP:0002151) | 2.23164840 |
58 | Missing ribs (HP:0000921) | 2.22089411 |
59 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.20569317 |
60 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.20569317 |
61 | Asplenia (HP:0001746) | 2.20395118 |
62 | Abnormal number of incisors (HP:0011064) | 2.17419231 |
63 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.16178612 |
64 | Abnormality of the anterior horn cell (HP:0006802) | 2.15210076 |
65 | Degeneration of anterior horn cells (HP:0002398) | 2.15210076 |
66 | Premature graying of hair (HP:0002216) | 2.10308625 |
67 | Premature skin wrinkling (HP:0100678) | 2.09111975 |
68 | Depressed nasal ridge (HP:0000457) | 2.07799925 |
69 | Colitis (HP:0002583) | 2.03754111 |
70 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.02826451 |
71 | Truncus arteriosus (HP:0001660) | 2.02628798 |
72 | Poikiloderma (HP:0001029) | 2.02289387 |
73 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.00880661 |
74 | Lymphoma (HP:0002665) | 2.00388064 |
75 | Atresia of the external auditory canal (HP:0000413) | 2.00362054 |
76 | Cerebral hypomyelination (HP:0006808) | 1.98348758 |
77 | Cellular immunodeficiency (HP:0005374) | 1.97559283 |
78 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.96828705 |
79 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.96213679 |
80 | Abnormality of the preputium (HP:0100587) | 1.95628536 |
81 | Amaurosis fugax (HP:0100576) | 1.95153592 |
82 | Pancytopenia (HP:0001876) | 1.94385198 |
83 | Stenosis of the external auditory canal (HP:0000402) | 1.93984525 |
84 | Glossoptosis (HP:0000162) | 1.93711865 |
85 | 3-Methylglutaconic aciduria (HP:0003535) | 1.93388165 |
86 | Premature ovarian failure (HP:0008209) | 1.92864510 |
87 | Triphalangeal thumb (HP:0001199) | 1.92294176 |
88 | Hypoplasia of the radius (HP:0002984) | 1.90653042 |
89 | Meckel diverticulum (HP:0002245) | 1.89564546 |
90 | Agnosia (HP:0010524) | 1.89411300 |
91 | Abnormality of small intestinal villus morphology (HP:0011472) | 1.89284099 |
92 | Villous atrophy (HP:0011473) | 1.89284099 |
93 | Increased IgE level (HP:0003212) | 1.88912276 |
94 | Duplication of thumb phalanx (HP:0009942) | 1.88649940 |
95 | Chronic otitis media (HP:0000389) | 1.87578997 |
96 | Abnormal trabecular bone morphology (HP:0100671) | 1.86583762 |
97 | Tracheoesophageal fistula (HP:0002575) | 1.86536393 |
98 | Squamous cell carcinoma (HP:0002860) | 1.85614908 |
99 | Bone marrow hypocellularity (HP:0005528) | 1.85414098 |
100 | Abnormal gallbladder physiology (HP:0012438) | 1.83600204 |
101 | Cholecystitis (HP:0001082) | 1.83600204 |
102 | Abnormality of the parietal bone (HP:0002696) | 1.83213072 |
103 | Chronic obstructive pulmonary disease (HP:0006510) | 1.82837151 |
104 | Obstructive lung disease (HP:0006536) | 1.82837151 |
105 | Abnormality of the ileum (HP:0001549) | 1.81879747 |
106 | Cleft eyelid (HP:0000625) | 1.81876253 |
107 | Abnormality of T cell physiology (HP:0011840) | 1.81830564 |
108 | Respiratory failure (HP:0002878) | 1.81760547 |
109 | Chromsome breakage (HP:0040012) | 1.81024181 |
110 | Thick lower lip vermilion (HP:0000179) | 1.80923263 |
111 | Gastrointestinal inflammation (HP:0004386) | 1.79782519 |
112 | Progressive muscle weakness (HP:0003323) | 1.79415714 |
113 | Abnormality of T cells (HP:0002843) | 1.79345138 |
114 | Myopathic facies (HP:0002058) | 1.79078676 |
115 | Proximal placement of thumb (HP:0009623) | 1.77562352 |
116 | Abnormal hemoglobin (HP:0011902) | 1.77511579 |
117 | Emotional lability (HP:0000712) | 1.74196945 |
118 | Horseshoe kidney (HP:0000085) | 1.74016393 |
119 | Cellulitis (HP:0100658) | 1.73421555 |
120 | Migraine (HP:0002076) | 1.73144946 |
121 | Absent radius (HP:0003974) | 1.71893080 |
122 | Abnormality of chromosome stability (HP:0003220) | 1.69863723 |
123 | Sparse eyelashes (HP:0000653) | 1.69090520 |
124 | Secondary amenorrhea (HP:0000869) | 1.67237373 |
125 | Type I transferrin isoform profile (HP:0003642) | 1.67154177 |
126 | Deviation of the thumb (HP:0009603) | 1.66637694 |
127 | Optic nerve coloboma (HP:0000588) | 1.66029030 |
128 | Small intestinal stenosis (HP:0012848) | 1.64530320 |
129 | Duodenal stenosis (HP:0100867) | 1.64530320 |
130 | Recurrent bronchitis (HP:0002837) | 1.63230754 |
131 | Nasolacrimal duct obstruction (HP:0000579) | 1.63082952 |
132 | Gastrointestinal stroma tumor (HP:0100723) | 1.61997353 |
133 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.61934301 |
134 | Acute lymphatic leukemia (HP:0006721) | 1.60338876 |
135 | Neoplasm of the colon (HP:0100273) | 1.60030018 |
136 | Recurrent viral infections (HP:0004429) | 1.58888003 |
137 | Rhabdomyosarcoma (HP:0002859) | 1.58602182 |
138 | Slender long bone (HP:0003100) | 1.58433866 |
139 | High anterior hairline (HP:0009890) | 1.58100604 |
140 | Deep palmar crease (HP:0006191) | 1.56827353 |
141 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.56133085 |
142 | Aplasia involving forearm bones (HP:0009822) | 1.55671939 |
143 | Absent forearm bone (HP:0003953) | 1.55671939 |
144 | Reticulocytosis (HP:0001923) | 1.55492322 |
145 | Muscle fiber atrophy (HP:0100295) | 1.54915708 |
146 | Neutropenia (HP:0001875) | 1.54827946 |
147 | Adenoma sebaceum (HP:0009720) | 1.54642967 |
148 | Angiofibromas (HP:0010615) | 1.54642967 |
149 | Abnormality of DNA repair (HP:0003254) | 1.54537169 |
150 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.54414414 |
151 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.54399058 |
152 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.54059166 |
153 | Abnormality of glycolysis (HP:0004366) | 1.53818428 |
154 | Abnormality of the umbilical cord (HP:0010881) | 1.52965718 |
155 | Exertional dyspnea (HP:0002875) | 1.52816438 |
156 | Preauricular skin tag (HP:0000384) | 1.52117694 |
157 | Dicarboxylic aciduria (HP:0003215) | 1.51959604 |
158 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.51959604 |
159 | Abnormal glycosylation (HP:0012345) | 1.51954767 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 4.91258678 |
2 | NME2 | 3.89704698 |
3 | BUB1 | 3.84274358 |
4 | SMG1 | 3.68290609 |
5 | WEE1 | 3.43247728 |
6 | EEF2K | 3.04288729 |
7 | CDC7 | 2.62207442 |
8 | RPS6KB2 | 2.48269584 |
9 | MAP4K1 | 2.22633925 |
10 | NEK2 | 2.13561680 |
11 | MAP3K10 | 2.07146469 |
12 | EIF2AK1 | 2.05121397 |
13 | PRPF4B | 2.03483541 |
14 | TESK2 | 2.00586000 |
15 | LRRK2 | 1.99436253 |
16 | STK16 | 1.94538526 |
17 | PASK | 1.93788167 |
18 | TLK1 | 1.91199193 |
19 | DYRK3 | 1.90637613 |
20 | TGFBR1 | 1.80899727 |
21 | PIM2 | 1.79398254 |
22 | RPS6KA4 | 1.66900006 |
23 | SRPK1 | 1.64390201 |
24 | PKN2 | 1.59278347 |
25 | VRK1 | 1.58888451 |
26 | TSSK6 | 1.57359770 |
27 | CDK7 | 1.57241713 |
28 | ARAF | 1.56679574 |
29 | FLT3 | 1.52333410 |
30 | KDR | 1.47577675 |
31 | ACVR1B | 1.47011062 |
32 | STK10 | 1.43114205 |
33 | SCYL2 | 1.42009865 |
34 | PAK4 | 1.41318779 |
35 | EIF2AK3 | 1.40977246 |
36 | IRAK3 | 1.39205790 |
37 | AURKB | 1.38325907 |
38 | EPHA2 | 1.36185535 |
39 | MAP3K8 | 1.35720567 |
40 | BRSK2 | 1.33618111 |
41 | TTK | 1.32040132 |
42 | MAPKAPK3 | 1.26356927 |
43 | TAF1 | 1.24861939 |
44 | CDK19 | 1.24340360 |
45 | PLK1 | 1.23484456 |
46 | CDK4 | 1.22002073 |
47 | ATR | 1.21820099 |
48 | BTK | 1.11557214 |
49 | MKNK1 | 1.11181353 |
50 | PLK4 | 1.09726514 |
51 | MAP2K3 | 1.08536185 |
52 | PIM1 | 1.07521819 |
53 | SIK1 | 1.04754019 |
54 | ZAP70 | 1.04483554 |
55 | BRAF | 1.02499015 |
56 | TAOK2 | 1.02383139 |
57 | ILK | 1.00953103 |
58 | ICK | 1.00114764 |
59 | MAP3K11 | 1.00099561 |
60 | PBK | 0.96361646 |
61 | TRIB3 | 0.94624374 |
62 | NEK1 | 0.93697988 |
63 | AURKA | 0.92575737 |
64 | STK4 | 0.91314331 |
65 | TESK1 | 0.83138786 |
66 | ZAK | 0.82117431 |
67 | GRK6 | 0.81788278 |
68 | CHEK1 | 0.79329952 |
69 | CDK12 | 0.78068966 |
70 | CHEK2 | 0.77916167 |
71 | IRAK4 | 0.76834570 |
72 | TYK2 | 0.73555567 |
73 | KIT | 0.73327868 |
74 | TEC | 0.73325026 |
75 | BCKDK | 0.71416648 |
76 | JAK3 | 0.71111336 |
77 | MST4 | 0.70842340 |
78 | PAK1 | 0.68775923 |
79 | BLK | 0.67907504 |
80 | CSNK2A2 | 0.67826474 |
81 | RPS6KA5 | 0.67760407 |
82 | MAP2K2 | 0.67181662 |
83 | BRSK1 | 0.64254683 |
84 | ERN1 | 0.62112717 |
85 | IKBKB | 0.61551583 |
86 | DYRK2 | 0.61480011 |
87 | ABL2 | 0.60962456 |
88 | DAPK1 | 0.60903772 |
89 | CSF1R | 0.58408938 |
90 | IRAK2 | 0.56778084 |
91 | PRKCI | 0.56481383 |
92 | CSNK2A1 | 0.54598011 |
93 | CDK2 | 0.54370618 |
94 | CLK1 | 0.53320850 |
95 | MKNK2 | 0.53113763 |
96 | DYRK1B | 0.52910717 |
97 | MAP3K3 | 0.52831098 |
98 | PAK2 | 0.52417721 |
99 | PTK6 | 0.52045782 |
100 | CDK6 | 0.51899760 |
101 | FES | 0.50045734 |
102 | ALK | 0.49685231 |
103 | CDK8 | 0.49635075 |
104 | MAPK11 | 0.48652970 |
105 | NLK | 0.48292487 |
106 | MUSK | 0.48004104 |
107 | ATM | 0.47696840 |
108 | HIPK2 | 0.46081779 |
109 | MAPKAPK5 | 0.44187177 |
110 | TBK1 | 0.44137680 |
111 | CDK9 | 0.43274348 |
112 | PLK3 | 0.43233717 |
113 | AKT2 | 0.40286465 |
114 | BMX | 0.39333819 |
115 | NME1 | 0.38706714 |
116 | IKBKE | 0.38504117 |
117 | DAPK3 | 0.38209521 |
118 | MAP3K13 | 0.37655853 |
119 | LCK | 0.36757437 |
120 | MAPKAPK2 | 0.36120675 |
121 | RPS6KA6 | 0.35491916 |
122 | MTOR | 0.35164849 |
123 | SYK | 0.34802346 |
124 | BRD4 | 0.34473851 |
125 | RPS6KL1 | 0.34320827 |
126 | RPS6KC1 | 0.34320827 |
127 | TNK2 | 0.33463848 |
128 | LYN | 0.31663191 |
129 | RPS6KA1 | 0.30651365 |
130 | CDK11A | 0.29279682 |
131 | ITK | 0.27558852 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Ribosome_Homo sapiens_hsa03010 | 6.02002318 |
2 | DNA replication_Homo sapiens_hsa03030 | 4.56105827 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 3.76009777 |
4 | Spliceosome_Homo sapiens_hsa03040 | 3.19756330 |
5 | Proteasome_Homo sapiens_hsa03050 | 3.10382819 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 3.03180395 |
7 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.91418348 |
8 | Base excision repair_Homo sapiens_hsa03410 | 2.78853267 |
9 | RNA transport_Homo sapiens_hsa03013 | 2.54899485 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.54436196 |
11 | Homologous recombination_Homo sapiens_hsa03440 | 2.51656409 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.40370610 |
13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.24032233 |
14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.17558786 |
15 | Cell cycle_Homo sapiens_hsa04110 | 2.02229741 |
16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.62069156 |
17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.59071281 |
18 | RNA degradation_Homo sapiens_hsa03018 | 1.57325856 |
19 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.45702782 |
20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.38524805 |
21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.33223888 |
22 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.24042114 |
23 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.23389133 |
24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.16087524 |
25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.15358301 |
26 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.12733866 |
27 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.12122733 |
28 | Purine metabolism_Homo sapiens_hsa00230 | 1.10234747 |
29 | Protein export_Homo sapiens_hsa03060 | 1.01615337 |
30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.00111667 |
31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.97268330 |
32 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.96414781 |
33 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.96097874 |
34 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.90172325 |
35 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.89813060 |
36 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.88508444 |
37 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.84156189 |
38 | Parkinsons disease_Homo sapiens_hsa05012 | 0.81331456 |
39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.80301451 |
40 | HTLV-I infection_Homo sapiens_hsa05166 | 0.78839506 |
41 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.76783639 |
42 | Huntingtons disease_Homo sapiens_hsa05016 | 0.75378199 |
43 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.73884827 |
44 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.68785799 |
45 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.68701377 |
46 | Thyroid cancer_Homo sapiens_hsa05216 | 0.68326130 |
47 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.66222238 |
48 | Legionellosis_Homo sapiens_hsa05134 | 0.65288150 |
49 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.62709792 |
50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.62606053 |
51 | Measles_Homo sapiens_hsa05162 | 0.62260415 |
52 | Apoptosis_Homo sapiens_hsa04210 | 0.61941847 |
53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.60214535 |
54 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.59161996 |
55 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.59158509 |
56 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.59007149 |
57 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.58754136 |
58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.58367059 |
59 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.57876935 |
60 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.57781674 |
61 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56483293 |
62 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.55545911 |
63 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.54562964 |
64 | Shigellosis_Homo sapiens_hsa05131 | 0.54101137 |
65 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.52780334 |
66 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.52519573 |
67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.51212856 |
68 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.49689796 |
69 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.48535014 |
70 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.46255774 |
71 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.44968069 |
72 | Bladder cancer_Homo sapiens_hsa05219 | 0.44899295 |
73 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.44089469 |
74 | Hepatitis B_Homo sapiens_hsa05161 | 0.42371667 |
75 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42208743 |
76 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.40901827 |
77 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.40529589 |
78 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.38739713 |
79 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.37726168 |
80 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.37390591 |
81 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.36976955 |
82 | Leishmaniasis_Homo sapiens_hsa05140 | 0.36601919 |
83 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.35938205 |
84 | Colorectal cancer_Homo sapiens_hsa05210 | 0.34752270 |
85 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.33657623 |
86 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.32046961 |
87 | Carbon metabolism_Homo sapiens_hsa01200 | 0.31663249 |
88 | Galactose metabolism_Homo sapiens_hsa00052 | 0.31247977 |
89 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.30888742 |
90 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.30708439 |
91 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.30608628 |
92 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.30249796 |
93 | Pathways in cancer_Homo sapiens_hsa05200 | 0.29602299 |
94 | Influenza A_Homo sapiens_hsa05164 | 0.29584359 |
95 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.28798549 |
96 | Alcoholism_Homo sapiens_hsa05034 | 0.28439482 |
97 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.27996455 |
98 | Viral myocarditis_Homo sapiens_hsa05416 | 0.27915207 |
99 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.27767353 |
100 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.25998172 |
101 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.25620297 |
102 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.25330294 |
103 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.24915600 |
104 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.24678435 |
105 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.24587360 |
106 | Alzheimers disease_Homo sapiens_hsa05010 | 0.24208007 |
107 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.24069459 |
108 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.23650783 |
109 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.23198832 |
110 | Other glycan degradation_Homo sapiens_hsa00511 | 0.22930553 |
111 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.22613920 |
112 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.22202499 |
113 | Allograft rejection_Homo sapiens_hsa05330 | 0.21796403 |
114 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.20896625 |
115 | Asthma_Homo sapiens_hsa05310 | 0.20135793 |
116 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.20118015 |
117 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.19791049 |
118 | Metabolic pathways_Homo sapiens_hsa01100 | 0.19004185 |
119 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.17903447 |
120 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.16722527 |