RPL19P13

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)6.46321113
2ribosomal small subunit biogenesis (GO:0042274)6.10216432
3viral transcription (GO:0019083)5.86588940
4translational termination (GO:0006415)5.67753821
5ribosomal small subunit assembly (GO:0000028)5.66739248
6energy coupled proton transport, down electrochemical gradient (GO:0015985)5.42653356
7ATP synthesis coupled proton transport (GO:0015986)5.42653356
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.32388304
9cotranslational protein targeting to membrane (GO:0006613)5.24510174
10protein targeting to ER (GO:0045047)5.18017082
11DNA deamination (GO:0045006)5.03920495
12establishment of protein localization to endoplasmic reticulum (GO:0072599)4.98438740
13protein localization to endoplasmic reticulum (GO:0070972)4.88176831
14translational elongation (GO:0006414)4.85789054
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.82974611
16rRNA catabolic process (GO:0016075)4.64519268
17mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.48926616
18mitochondrial respiratory chain complex I assembly (GO:0032981)4.48926616
19NADH dehydrogenase complex assembly (GO:0010257)4.48926616
20protein complex biogenesis (GO:0070271)4.41291830
21nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.26590773
22cellular protein complex disassembly (GO:0043624)4.14666780
23viral life cycle (GO:0019058)4.12196975
24behavioral response to nicotine (GO:0035095)4.07676346
25mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.05877645
26tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.00612879
27RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.00612879
28mitochondrial respiratory chain complex assembly (GO:0033108)4.00283354
29ribosomal large subunit biogenesis (GO:0042273)3.89506296
30response to pheromone (GO:0019236)3.86406433
31parturition (GO:0007567)3.84446730
32cornea development in camera-type eye (GO:0061303)3.71863378
33exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.70820488
34electron transport chain (GO:0022900)3.69027135
35respiratory electron transport chain (GO:0022904)3.65322011
36translational initiation (GO:0006413)3.65096662
37nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.58694360
38translation (GO:0006412)3.56575420
39cellular response to ATP (GO:0071318)3.45882332
40nonmotile primary cilium assembly (GO:0035058)3.43039688
41protein targeting to membrane (GO:0006612)3.40750597
42GTP biosynthetic process (GO:0006183)3.35972447
43protein complex disassembly (GO:0043241)3.35734611
44nuclear-transcribed mRNA catabolic process (GO:0000956)3.35545908
45base-excision repair, AP site formation (GO:0006285)3.33624587
46chaperone-mediated protein transport (GO:0072321)3.32889692
47response to xenobiotic stimulus (GO:0009410)3.28370690
48RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.27357599
49resolution of meiotic recombination intermediates (GO:0000712)3.27307584
50detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.26397036
51establishment of protein localization to mitochondrial membrane (GO:0090151)3.19088917
52purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.18514100
53purine nucleoside triphosphate biosynthetic process (GO:0009145)3.18278976
54cellular component biogenesis (GO:0044085)3.15368181
55ncRNA catabolic process (GO:0034661)3.14115312
56mRNA catabolic process (GO:0006402)3.13946559
57ATP biosynthetic process (GO:0006754)3.13000937
58macromolecular complex disassembly (GO:0032984)3.12160431
59rRNA modification (GO:0000154)3.11820707
60regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:00033393.05811438
61kynurenine metabolic process (GO:0070189)3.04837478
62ribonucleoprotein complex biogenesis (GO:0022613)2.95481889
63respiratory chain complex IV assembly (GO:0008535)2.94263944
64inner mitochondrial membrane organization (GO:0007007)2.91892733
65RNA catabolic process (GO:0006401)2.90139318
66negative regulation of response to food (GO:0032096)2.89974718
67negative regulation of appetite (GO:0032099)2.89974718
68mannosylation (GO:0097502)2.86093574
69regulation of mitochondrial translation (GO:0070129)2.85891249
70negative regulation of mast cell activation (GO:0033004)2.84346912
71cytochrome complex assembly (GO:0017004)2.82940013
72tryptophan catabolic process (GO:0006569)2.81300320
73indole-containing compound catabolic process (GO:0042436)2.81300320
74indolalkylamine catabolic process (GO:0046218)2.81300320
75hydrogen ion transmembrane transport (GO:1902600)2.80694523
76cullin deneddylation (GO:0010388)2.80553726
77spinal cord association neuron differentiation (GO:0021527)2.77567629
78glycerophospholipid catabolic process (GO:0046475)2.77025561
79thyroid hormone generation (GO:0006590)2.74977542
80regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.72483459
81artery smooth muscle contraction (GO:0014824)2.71714146
82regulation of cilium movement (GO:0003352)2.71235148
83DNA excision (GO:0044349)2.69887711
84nucleotide-excision repair, DNA damage removal (GO:0000718)2.69887711
85UTP biosynthetic process (GO:0006228)2.69491791
86platelet dense granule organization (GO:0060155)2.68165742
87thyroid hormone metabolic process (GO:0042403)2.64710931
88ribonucleoside triphosphate biosynthetic process (GO:0009201)2.64652402
89rRNA metabolic process (GO:0016072)2.60653976
90protein deneddylation (GO:0000338)2.60431114
91protein-cofactor linkage (GO:0018065)2.59457680
92UTP metabolic process (GO:0046051)2.58322584
93rRNA processing (GO:0006364)2.57954850
94proton transport (GO:0015992)2.55435029
95regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.53211205
96nephron epithelium morphogenesis (GO:0072088)2.50480609
97nephron tubule morphogenesis (GO:0072078)2.50480609
98short-term memory (GO:0007614)2.49619334
99T cell migration (GO:0072678)2.49140223
100hydrogen transport (GO:0006818)2.48488217

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.37355247
2VDR_22108803_ChIP-Seq_LS180_Human4.11573523
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.32022950
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.07682408
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.98033104
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.88546615
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.79035309
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.78743804
9ZNF274_21170338_ChIP-Seq_K562_Hela2.77429703
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.64530163
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.44019039
12MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.12547999
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.08765354
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.08097741
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.01824576
16STAT6_21828071_ChIP-Seq_BEAS2B_Human1.96165990
17IRF8_22096565_ChIP-ChIP_GC-B_Human1.87690590
18ELK1_19687146_ChIP-ChIP_HELA_Human1.87291330
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.85822975
20MYC_18940864_ChIP-ChIP_HL60_Human1.84643827
21GBX2_23144817_ChIP-Seq_PC3_Human1.82707220
22TP53_22573176_ChIP-Seq_HFKS_Human1.78733852
23EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.75213873
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.70009223
25BMI1_23680149_ChIP-Seq_NPCS_Mouse1.60786203
26FLI1_27457419_Chip-Seq_LIVER_Mouse1.56160317
27VDR_23849224_ChIP-Seq_CD4+_Human1.55111615
28IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.52598020
29BP1_19119308_ChIP-ChIP_Hs578T_Human1.51854106
30YY1_21170310_ChIP-Seq_MESCs_Mouse1.45844468
31CBX2_27304074_Chip-Seq_ESCs_Mouse1.38910826
32AR_21572438_ChIP-Seq_LNCaP_Human1.37384618
33MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36862008
34EWS_26573619_Chip-Seq_HEK293_Human1.36405154
35NANOG_20526341_ChIP-Seq_ESCs_Human1.36233586
36PCGF2_27294783_Chip-Seq_ESCs_Mouse1.36209591
37EZH2_27304074_Chip-Seq_ESCs_Mouse1.35545067
38FOXP3_21729870_ChIP-Seq_TREG_Human1.33421082
39EED_16625203_ChIP-ChIP_MESCs_Mouse1.32482216
40SRY_22984422_ChIP-ChIP_TESTIS_Rat1.31096631
41P300_19829295_ChIP-Seq_ESCs_Human1.30670708
42EZH2_27294783_Chip-Seq_ESCs_Mouse1.29450791
43FOXA1_27270436_Chip-Seq_PROSTATE_Human1.29438382
44FOXA1_25329375_ChIP-Seq_VCAP_Human1.29438382
45AR_20517297_ChIP-Seq_VCAP_Human1.28797395
46PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28581279
47TAF2_19829295_ChIP-Seq_ESCs_Human1.26733003
48SRF_21415370_ChIP-Seq_HL-1_Mouse1.26208113
49ELF1_17652178_ChIP-ChIP_JURKAT_Human1.25277496
50POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.23122634
51PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.20545986
52TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.20359441
53POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.20359441
54AUTS2_25519132_ChIP-Seq_293T-REX_Human1.20326540
55IGF1R_20145208_ChIP-Seq_DFB_Human1.19618737
56ERA_21632823_ChIP-Seq_H3396_Human1.18274347
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.17702837
58GATA3_26560356_Chip-Seq_TH2_Human1.16075657
59GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15465262
60NANOG_19829295_ChIP-Seq_ESCs_Human1.13299644
61SOX2_19829295_ChIP-Seq_ESCs_Human1.13299644
62ER_23166858_ChIP-Seq_MCF-7_Human1.12964159
63CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.12143118
64JARID2_20064375_ChIP-Seq_MESCs_Mouse1.11807523
65GATA3_21878914_ChIP-Seq_MCF-7_Human1.10538179
66RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08497528
67POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08398218
68REST_21632747_ChIP-Seq_MESCs_Mouse1.06096621
69NCOR_22424771_ChIP-Seq_293T_Human1.05676983
70PCGF2_27294783_Chip-Seq_NPCs_Mouse1.04549878
71ELK1_22589737_ChIP-Seq_MCF10A_Human1.03857565
72CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.03337346
73MYC_18358816_ChIP-ChIP_MESCs_Mouse1.03062767
74CTBP1_25329375_ChIP-Seq_LNCAP_Human1.01814493
75STAT1_20625510_ChIP-Seq_HELA_Human1.01190814
76GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95147124
77CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94371542
78SUZ12_27294783_Chip-Seq_ESCs_Mouse0.94056828
79PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.93670218
80CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.92832230
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.92272926
82CBP_20019798_ChIP-Seq_JUKART_Human0.92272926
83UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91808727
84CTCF_20526341_ChIP-Seq_ESCs_Human0.91625348
85GATA6_21074721_ChIP-Seq_CACO-2_Human0.90424661
86JARID2_20075857_ChIP-Seq_MESCs_Mouse0.90379022
87NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.90176426
88LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.89796487
89LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89574117
90IRF1_19129219_ChIP-ChIP_H3396_Human0.89238529
91TP53_20018659_ChIP-ChIP_R1E_Mouse0.88684559
92HOXB7_26014856_ChIP-Seq_BT474_Human0.88118460
93FOXH1_21741376_ChIP-Seq_EPCs_Human0.87664312
94PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.86611078
95RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.85542047
96MYC_19829295_ChIP-Seq_ESCs_Human0.85293980
97SOX2_16153702_ChIP-ChIP_HESCs_Human0.85163537
98WDR5_24793694_ChIP-Seq_LNCAP_Human0.85129463
99GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.84907337
100OCT4_20526341_ChIP-Seq_ESCs_Human0.84356111

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.26544593
2MP0002102_abnormal_ear_morphology3.30615911
3MP0004885_abnormal_endolymph3.02059470
4MP0004145_abnormal_muscle_electrophysio3.01409195
5MP0006292_abnormal_olfactory_placode2.86716987
6MP0001529_abnormal_vocalization2.81011825
7MP0002163_abnormal_gland_morphology2.80488018
8MP0004142_abnormal_muscle_tone2.68989600
9MP0003878_abnormal_ear_physiology2.57366107
10MP0005377_hearing/vestibular/ear_phenot2.57366107
11MP0004147_increased_porphyrin_level2.35838441
12MP0001485_abnormal_pinna_reflex2.30803337
13MP0000372_irregular_coat_pigmentation2.20046181
14MP0008875_abnormal_xenobiotic_pharmacok2.17458656
15MP0006072_abnormal_retinal_apoptosis2.09469110
16MP0008789_abnormal_olfactory_epithelium2.00500102
17MP0008995_early_reproductive_senescence1.90098036
18MP0002736_abnormal_nociception_after1.79517646
19MP0003646_muscle_fatigue1.77392851
20MP0005671_abnormal_response_to1.76073916
21MP0008877_abnormal_DNA_methylation1.75830294
22MP0002234_abnormal_pharynx_morphology1.75042073
23MP0005551_abnormal_eye_electrophysiolog1.71929294
24MP0002653_abnormal_ependyma_morphology1.64113556
25MP0005379_endocrine/exocrine_gland_phen1.55085774
26MP0000049_abnormal_middle_ear1.51880260
27MP0001905_abnormal_dopamine_level1.50417952
28MP0001835_abnormal_antigen_presentation1.50054448
29MP0005253_abnormal_eye_physiology1.48180428
30MP0003195_calcinosis1.47985104
31MP0009745_abnormal_behavioral_response1.47282336
32MP0004742_abnormal_vestibular_system1.47093288
33MP0001968_abnormal_touch/_nociception1.46101410
34MP0002938_white_spotting1.45573130
35MP0000631_abnormal_neuroendocrine_gland1.40694496
36MP0000569_abnormal_digit_pigmentation1.39972436
37MP0005645_abnormal_hypothalamus_physiol1.35456103
38MP0003186_abnormal_redox_activity1.35221597
39MP0005499_abnormal_olfactory_system1.30910546
40MP0005394_taste/olfaction_phenotype1.30910546
41MP0008872_abnormal_physiological_respon1.26049472
42MP0005389_reproductive_system_phenotype1.25605187
43MP0006036_abnormal_mitochondrial_physio1.25604085
44MP0001764_abnormal_homeostasis1.24687389
45MP0001984_abnormal_olfaction1.24024562
46MP0005646_abnormal_pituitary_gland1.20516864
47MP0002095_abnormal_skin_pigmentation1.19264351
48MP0002272_abnormal_nervous_system1.16412437
49MP0004133_heterotaxia1.16031473
50MP0001542_abnormal_bone_strength1.14475253
51MP0009785_altered_susceptibility_to1.13220937
52MP0003786_premature_aging1.12802095
53MP0001919_abnormal_reproductive_system1.12759517
54MP0005423_abnormal_somatic_nervous1.12441224
55MP0002090_abnormal_vision1.12252880
56MP0005195_abnormal_posterior_eye1.07396079
57MP0009046_muscle_twitch1.06465417
58MP0008775_abnormal_heart_ventricle1.04622403
59MP0001963_abnormal_hearing_physiology1.03408639
60MP0003787_abnormal_imprinting1.02436072
61MP0003122_maternal_imprinting1.01330841
62MP0005408_hypopigmentation1.01160510
63MP0009764_decreased_sensitivity_to0.99824697
64MP0005332_abnormal_amino_acid0.97419525
65MP0003045_fibrosis0.95750175
66MP0001970_abnormal_pain_threshold0.93826106
67MP0003329_amyloid_beta_deposits0.92409011
68MP0002148_abnormal_hypersensitivity_rea0.92355998
69MP0001486_abnormal_startle_reflex0.91815608
70MP0001800_abnormal_humoral_immune0.91599164
71MP0000026_abnormal_inner_ear0.91356279
72MP0001501_abnormal_sleep_pattern0.89013833
73MP0005387_immune_system_phenotype0.88435437
74MP0001790_abnormal_immune_system0.88435437
75MP0001293_anophthalmia0.87474463
76MP0002572_abnormal_emotion/affect_behav0.86163092
77MP0001986_abnormal_taste_sensitivity0.86108600
78MP0009384_cardiac_valve_regurgitation0.85465183
79MP0002557_abnormal_social/conspecific_i0.84834842
80MP0005167_abnormal_blood-brain_barrier0.84130614
81MP0009333_abnormal_splenocyte_physiolog0.83694511
82MP0001440_abnormal_grooming_behavior0.83264565
83MP0005075_abnormal_melanosome_morpholog0.80896735
84MP0002752_abnormal_somatic_nervous0.80719521
85MP0003123_paternal_imprinting0.79199024
86MP0001324_abnormal_eye_pigmentation0.77346871
87MP0003137_abnormal_impulse_conducting0.76578695
88MP0003011_delayed_dark_adaptation0.76574453
89MP0002638_abnormal_pupillary_reflex0.74801857
90MP0003866_abnormal_defecation0.74315557
91MP0003119_abnormal_digestive_system0.74220423
92MP0002064_seizures0.73713318
93MP0004924_abnormal_behavior0.72876311
94MP0005386_behavior/neurological_phenoty0.72876311
95MP0002876_abnormal_thyroid_physiology0.72774252
96MP0000343_altered_response_to0.70417490
97MP0002837_dystrophic_cardiac_calcinosis0.70350039
98MP0009643_abnormal_urine_homeostasis0.69886631
99MP0003942_abnormal_urinary_system0.69392644
100MP0002733_abnormal_thermal_nociception0.69115622

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.53464350
2Acute necrotizing encephalopathy (HP:0006965)4.37120176
3Acute encephalopathy (HP:0006846)3.77277884
4Abnormal mitochondria in muscle tissue (HP:0008316)3.75737985
5Progressive macrocephaly (HP:0004481)3.74219069
6Mitochondrial inheritance (HP:0001427)3.56018623
7Hypoplasia of the pons (HP:0012110)3.52573410
8Abnormality of cells of the erythroid lineage (HP:0012130)3.51216023
9Abnormality of DNA repair (HP:0003254)3.48385926
10Stomatitis (HP:0010280)3.29619860
11Hepatocellular necrosis (HP:0001404)3.28952764
12Abnormality of the pons (HP:0007361)3.28126515
13Abolished electroretinogram (ERG) (HP:0000550)3.21454805
14Congenital stationary night blindness (HP:0007642)3.16039084
15Increased CSF lactate (HP:0002490)3.02436491
16IgG deficiency (HP:0004315)2.99181627
17Pancreatic cysts (HP:0001737)2.92502577
18Abnormal hemoglobin (HP:0011902)2.91869076
19Type II lissencephaly (HP:0007260)2.89937410
203-Methylglutaconic aciduria (HP:0003535)2.84664637
21Macrocytic anemia (HP:0001972)2.79883488
22Hepatic necrosis (HP:0002605)2.78129564
23Spastic paraparesis (HP:0002313)2.75094939
24Abnormal number of erythroid precursors (HP:0012131)2.69188319
25Pancreatic fibrosis (HP:0100732)2.65848122
26Asplenia (HP:0001746)2.60292125
27Cerebral edema (HP:0002181)2.60185495
28Hypoplastic left heart (HP:0004383)2.57720403
29Hypoproteinemia (HP:0003075)2.56881722
30Testicular atrophy (HP:0000029)2.51197572
31Poor head control (HP:0002421)2.51152637
32Pallor (HP:0000980)2.50971016
33Abnormality of midbrain morphology (HP:0002418)2.49834417
34Molar tooth sign on MRI (HP:0002419)2.49834417
35True hermaphroditism (HP:0010459)2.47364190
36Neoplasm of the adrenal cortex (HP:0100641)2.46074067
37Concave nail (HP:0001598)2.45080186
38Optic disc pallor (HP:0000543)2.43114764
39Aplasia/Hypoplasia of the spleen (HP:0010451)2.41944674
40Anterior segment dysgenesis (HP:0007700)2.38670471
41Medial flaring of the eyebrow (HP:0010747)2.26146964
42Congenital, generalized hypertrichosis (HP:0004540)2.25914380
43Metabolic alkalosis (HP:0200114)2.23213695
44Lipid accumulation in hepatocytes (HP:0006561)2.20637786
45Decreased electroretinogram (ERG) amplitude (HP:0000654)2.20546820
46Elevated erythrocyte sedimentation rate (HP:0003565)2.20295607
47Pendular nystagmus (HP:0012043)2.19658582
48Cerebral palsy (HP:0100021)2.18371802
49Sclerocornea (HP:0000647)2.16272455
50Decreased subcutaneous fat (HP:0001002)2.13476180
51Attenuation of retinal blood vessels (HP:0007843)2.09767203
52Increased hepatocellular lipid droplets (HP:0006565)2.09734000
53Abnormality of the prostate (HP:0008775)2.07397850
54Colon cancer (HP:0003003)2.04358599
55Clumsiness (HP:0002312)2.02735859
56Stenosis of the external auditory canal (HP:0000402)2.02409249
57Hypoplastic heart (HP:0001961)2.00941609
58Aplastic anemia (HP:0001915)1.98869683
59Septo-optic dysplasia (HP:0100842)1.98484992
60Optic nerve hypoplasia (HP:0000609)1.96890773
61Abnormality of T cell physiology (HP:0011840)1.96156214
62Hypoplasia of the fovea (HP:0007750)1.94928135
63Aplasia/Hypoplasia of the fovea (HP:0008060)1.94928135
64Methylmalonic acidemia (HP:0002912)1.94759510
65Increased corneal curvature (HP:0100692)1.92867158
66Keratoconus (HP:0000563)1.92867158
67Leukodystrophy (HP:0002415)1.92791902
68Abnormality of the proximal phalanges of the hand (HP:0009834)1.91755752
69Opisthotonus (HP:0002179)1.91555811
70Abnormality of the renal cortex (HP:0011035)1.90939270
71Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.90442657
72Absent rod-and cone-mediated responses on ERG (HP:0007688)1.89837936
73Absent thumb (HP:0009777)1.89370023
74Nephronophthisis (HP:0000090)1.88745064
75Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.87649092
76Stomach cancer (HP:0012126)1.87628318
77Polyuria (HP:0000103)1.82746059
78Abnormal rod and cone electroretinograms (HP:0008323)1.82697074
79Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.82535109
80Abnormal protein N-linked glycosylation (HP:0012347)1.82535109
81Abnormal protein glycosylation (HP:0012346)1.82535109
82Abnormal glycosylation (HP:0012345)1.82535109
83Partial agenesis of the corpus callosum (HP:0001338)1.80768926
84Increased serum lactate (HP:0002151)1.79411101
85Renal Fanconi syndrome (HP:0001994)1.78575728
86Abnormality of the renal medulla (HP:0100957)1.75718765
87Neutropenia (HP:0001875)1.74954834
88Degeneration of anterior horn cells (HP:0002398)1.74465760
89Abnormality of the anterior horn cell (HP:0006802)1.74465760
90Respiratory failure (HP:0002878)1.74253340
91Tubular atrophy (HP:0000092)1.72940083
92Abnormality of B cell number (HP:0010975)1.72833141
93Enlarged kidneys (HP:0000105)1.71698251
94Male pseudohermaphroditism (HP:0000037)1.70588912
95Cerebellar dysplasia (HP:0007033)1.69689237
96Abnormality of the renal collecting system (HP:0004742)1.69412969
97Congenital primary aphakia (HP:0007707)1.69369066
98Poor coordination (HP:0002370)1.69014353
99Methylmalonic aciduria (HP:0012120)1.68355725
100Prostate neoplasm (HP:0100787)1.66075426

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE13.08026380
2ADRBK23.04736706
3ZAK2.78527648
4GRK12.77388202
5BCKDK2.66111785
6MAP3K132.46948242
7FRK2.44212266
8PIK3CA2.29656194
9VRK22.19376849
10NEK12.12188533
11BMPR21.97652009
12SMG11.93276005
13GRK71.88498667
14CAMK11.80469025
15MAP3K41.78438608
16RIPK41.76649751
17EPHA41.71217055
18WNK41.66507786
19GRK61.57181805
20NEK21.50668989
21KIT1.49015940
22TLK11.42801492
23MAP2K71.40613892
24IKBKB1.40435344
25DYRK1B1.30920493
26DYRK21.28644846
27INSRR1.27586884
28NUAK11.21315338
29ADRBK11.17545254
30CAMKK21.17204378
31GRK51.12529490
32SYK1.08834983
33DAPK31.08278161
34WNK31.02203208
35MAP3K60.99036590
36CDK190.98336975
37VRK10.96793822
38PKN10.96738164
39CSNK1G20.96434082
40RPS6KA60.95766321
41CSNK1G30.93654308
42PLK30.92907493
43PLK40.90360499
44TEC0.88855092
45EIF2AK10.87527525
46NME10.87154007
47MKNK20.86910362
48MAP3K70.85854505
49PLK20.85636839
50CAMK40.85212515
51ITK0.84872285
52JAK30.83172648
53CHEK20.81790804
54OXSR10.81737414
55MKNK10.81636772
56AURKA0.79743113
57PLK10.79032047
58IKBKE0.78890924
59BTK0.78841816
60KDR0.76374909
61PRKACA0.75144039
62PIM10.74455071
63EIF2AK30.73894710
64PRKCG0.73875640
65DAPK20.73362662
66ERBB20.71473101
67LYN0.71286955
68PINK10.70332688
69RPS6KC10.68047368
70RPS6KL10.68047368
71CSNK1G10.66410566
72NME20.66409600
73OBSCN0.64963466
74CAMK1G0.64759229
75NTRK30.63707977
76TXK0.63455779
77PRKCE0.63210433
78SIK20.63023434
79PRKCD0.61945277
80TAOK30.61251034
81CSNK1A1L0.59801912
82NTRK20.58082252
83MAP4K10.57699790
84PRKCQ0.57551363
85PIK3CG0.56683356
86ATR0.56177433
87STK390.55629922
88CSNK2A20.55570265
89CSNK1A10.55016365
90MAP4K20.54659808
91PRKCA0.54599092
92BMPR1B0.53621524
93AURKB0.53547711
94MAPKAPK50.51211139
95CDC70.49111561
96MARK20.48924282
97CSNK2A10.48857808
98RPS6KA50.48567486
99CAMK1D0.48491528
100TAF10.44776619

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.90129295
2Oxidative phosphorylation_Homo sapiens_hsa001904.02085936
3Protein export_Homo sapiens_hsa030603.16086240
4Parkinsons disease_Homo sapiens_hsa050123.14361713
5Asthma_Homo sapiens_hsa053102.95947165
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.88327802
7Allograft rejection_Homo sapiens_hsa053302.59336243
8Autoimmune thyroid disease_Homo sapiens_hsa053202.43833826
9Proteasome_Homo sapiens_hsa030502.43796839
10Alzheimers disease_Homo sapiens_hsa050102.22518250
11Huntingtons disease_Homo sapiens_hsa050162.14844792
12Sulfur metabolism_Homo sapiens_hsa009202.04322986
13Graft-versus-host disease_Homo sapiens_hsa053321.99194734
14Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.97097952
15Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.94212524
16Homologous recombination_Homo sapiens_hsa034401.90071770
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.84253310
18Linoleic acid metabolism_Homo sapiens_hsa005911.82667598
19RNA degradation_Homo sapiens_hsa030181.77281766
20Cardiac muscle contraction_Homo sapiens_hsa042601.77082981
21Type I diabetes mellitus_Homo sapiens_hsa049401.70827584
22alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.70639667
23Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.70084566
24Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.51156943
25Nitrogen metabolism_Homo sapiens_hsa009101.44243889
26Sulfur relay system_Homo sapiens_hsa041221.42459340
27Nucleotide excision repair_Homo sapiens_hsa034201.40412095
28Primary immunodeficiency_Homo sapiens_hsa053401.35865604
29Rheumatoid arthritis_Homo sapiens_hsa053231.35103328
30Arachidonic acid metabolism_Homo sapiens_hsa005901.32409952
31Fanconi anemia pathway_Homo sapiens_hsa034601.16665435
32Phototransduction_Homo sapiens_hsa047441.15758697
33RNA polymerase_Homo sapiens_hsa030201.14186023
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12447789
35Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.11711721
36Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.11680042
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.11551411
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.09501330
39Chemical carcinogenesis_Homo sapiens_hsa052041.08553254
40Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96812554
41Nicotine addiction_Homo sapiens_hsa050330.95891043
42Collecting duct acid secretion_Homo sapiens_hsa049660.95746706
43Basal transcription factors_Homo sapiens_hsa030220.94341294
44Glutathione metabolism_Homo sapiens_hsa004800.93737391
45Viral myocarditis_Homo sapiens_hsa054160.92235391
46Tryptophan metabolism_Homo sapiens_hsa003800.91320846
47Cysteine and methionine metabolism_Homo sapiens_hsa002700.89520381
48RNA transport_Homo sapiens_hsa030130.87813477
49Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.87029107
50SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86462915
51Peroxisome_Homo sapiens_hsa041460.82073395
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81671768
53Ether lipid metabolism_Homo sapiens_hsa005650.78759653
54Morphine addiction_Homo sapiens_hsa050320.75992160
55Vitamin B6 metabolism_Homo sapiens_hsa007500.75007915
56Base excision repair_Homo sapiens_hsa034100.66823207
57Retinol metabolism_Homo sapiens_hsa008300.66599017
58Steroid hormone biosynthesis_Homo sapiens_hsa001400.65502303
59Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.63474612
60Mismatch repair_Homo sapiens_hsa034300.61647322
61Spliceosome_Homo sapiens_hsa030400.59451077
62Antigen processing and presentation_Homo sapiens_hsa046120.58127297
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57039754
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.56639061
65Pyrimidine metabolism_Homo sapiens_hsa002400.56260039
66Vitamin digestion and absorption_Homo sapiens_hsa049770.55770804
67beta-Alanine metabolism_Homo sapiens_hsa004100.55003945
68Metabolic pathways_Homo sapiens_hsa011000.53804686
69Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53801652
70Ovarian steroidogenesis_Homo sapiens_hsa049130.52936061
71Maturity onset diabetes of the young_Homo sapiens_hsa049500.51668455
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.51571960
73Systemic lupus erythematosus_Homo sapiens_hsa053220.50363629
74Folate biosynthesis_Homo sapiens_hsa007900.50342690
75Staphylococcus aureus infection_Homo sapiens_hsa051500.50114174
76Butanoate metabolism_Homo sapiens_hsa006500.48353299
77Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47272165
78Purine metabolism_Homo sapiens_hsa002300.45884636
79Olfactory transduction_Homo sapiens_hsa047400.45033900
80Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.44309404
81DNA replication_Homo sapiens_hsa030300.42511094
82Taste transduction_Homo sapiens_hsa047420.42478051
83Histidine metabolism_Homo sapiens_hsa003400.41294581
84Caffeine metabolism_Homo sapiens_hsa002320.41166879
85p53 signaling pathway_Homo sapiens_hsa041150.39573584
86Tyrosine metabolism_Homo sapiens_hsa003500.38539243
87Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.34591654
88N-Glycan biosynthesis_Homo sapiens_hsa005100.32699132
89Pentose and glucuronate interconversions_Homo sapiens_hsa000400.31393656
90Primary bile acid biosynthesis_Homo sapiens_hsa001200.30693816
91Fat digestion and absorption_Homo sapiens_hsa049750.30232873
92Selenocompound metabolism_Homo sapiens_hsa004500.29704415
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.28393617
94Calcium signaling pathway_Homo sapiens_hsa040200.26453059
95Serotonergic synapse_Homo sapiens_hsa047260.25576240
96Circadian entrainment_Homo sapiens_hsa047130.25035948
97Glutamatergic synapse_Homo sapiens_hsa047240.24971999
98One carbon pool by folate_Homo sapiens_hsa006700.22814356
99Propanoate metabolism_Homo sapiens_hsa006400.22359042
100GABAergic synapse_Homo sapiens_hsa047270.20823129

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