

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.13118621 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.13118621 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.00124556 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 4.99543904 |
| 5 | viral transcription (GO:0019083) | 4.70224160 |
| 6 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.65271796 |
| 7 | respiratory electron transport chain (GO:0022904) | 4.56994300 |
| 8 | electron transport chain (GO:0022900) | 4.53551206 |
| 9 | translational termination (GO:0006415) | 4.53022321 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.44692572 |
| 11 | cotranslational protein targeting to membrane (GO:0006613) | 4.40298828 |
| 12 | protein targeting to ER (GO:0045047) | 4.37854162 |
| 13 | DNA deamination (GO:0045006) | 4.26302306 |
| 14 | protein neddylation (GO:0045116) | 4.22825814 |
| 15 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.18942184 |
| 16 | protein localization to endoplasmic reticulum (GO:0070972) | 4.16722322 |
| 17 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.15621217 |
| 18 | translational elongation (GO:0006414) | 4.00491435 |
| 19 | ribosomal large subunit biogenesis (GO:0042273) | 3.85185621 |
| 20 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.83243867 |
| 21 | protein complex biogenesis (GO:0070271) | 3.76410056 |
| 22 | ATP biosynthetic process (GO:0006754) | 3.69164266 |
| 23 | respiratory chain complex IV assembly (GO:0008535) | 3.64538410 |
| 24 | hydrogen ion transmembrane transport (GO:1902600) | 3.63138849 |
| 25 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.60990750 |
| 26 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.56393873 |
| 27 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.56026711 |
| 28 | maturation of SSU-rRNA (GO:0030490) | 3.54015666 |
| 29 | negative regulation of heart rate (GO:0010459) | 3.47973586 |
| 30 | translation (GO:0006412) | 3.44764858 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.41060346 |
| 32 | proton transport (GO:0015992) | 3.40888158 |
| 33 | positive regulation of interleukin-17 production (GO:0032740) | 3.39908552 |
| 34 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.39154584 |
| 35 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.38938582 |
| 36 | cytochrome complex assembly (GO:0017004) | 3.36402974 |
| 37 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.36365668 |
| 38 | hydrogen transport (GO:0006818) | 3.34361862 |
| 39 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.33814817 |
| 40 | viral life cycle (GO:0019058) | 3.29583967 |
| 41 | cellular protein complex disassembly (GO:0043624) | 3.27983941 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.26780375 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.26780375 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.26780375 |
| 45 | regulation of chronic inflammatory response (GO:0002676) | 3.22311529 |
| 46 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.19185638 |
| 47 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.19185638 |
| 48 | translational initiation (GO:0006413) | 3.19155953 |
| 49 | GTP biosynthetic process (GO:0006183) | 3.15954298 |
| 50 | regulation of regulatory T cell differentiation (GO:0045589) | 3.11271905 |
| 51 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.11223987 |
| 52 | termination of RNA polymerase III transcription (GO:0006386) | 3.11223987 |
| 53 | regulation of immunoglobulin secretion (GO:0051023) | 3.06837779 |
| 54 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.05166587 |
| 55 | behavioral response to nicotine (GO:0035095) | 3.00254903 |
| 56 | ribosomal small subunit biogenesis (GO:0042274) | 3.00191543 |
| 57 | negative regulation of mast cell activation (GO:0033004) | 2.98569690 |
| 58 | proteasome assembly (GO:0043248) | 2.93455392 |
| 59 | kynurenine metabolic process (GO:0070189) | 2.92397206 |
| 60 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.91753806 |
| 61 | tryptophan catabolic process (GO:0006569) | 2.90274426 |
| 62 | indole-containing compound catabolic process (GO:0042436) | 2.90274426 |
| 63 | indolalkylamine catabolic process (GO:0046218) | 2.90274426 |
| 64 | protein targeting to membrane (GO:0006612) | 2.84797719 |
| 65 | S-adenosylmethionine metabolic process (GO:0046500) | 2.80858353 |
| 66 | fucose catabolic process (GO:0019317) | 2.79779096 |
| 67 | L-fucose metabolic process (GO:0042354) | 2.79779096 |
| 68 | L-fucose catabolic process (GO:0042355) | 2.79779096 |
| 69 | platelet dense granule organization (GO:0060155) | 2.79393458 |
| 70 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.78727107 |
| 71 | cytidine deamination (GO:0009972) | 2.78092061 |
| 72 | cytidine metabolic process (GO:0046087) | 2.78092061 |
| 73 | cytidine catabolic process (GO:0006216) | 2.78092061 |
| 74 | signal peptide processing (GO:0006465) | 2.62022591 |
| 75 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.61347701 |
| 76 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.60259815 |
| 77 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.59948284 |
| 78 | protein-cofactor linkage (GO:0018065) | 2.59545082 |
| 79 | rRNA catabolic process (GO:0016075) | 2.58782124 |
| 80 | indolalkylamine metabolic process (GO:0006586) | 2.58524939 |
| 81 | mast cell activation (GO:0045576) | 2.57472370 |
| 82 | protein complex disassembly (GO:0043241) | 2.56004198 |
| 83 | chaperone-mediated protein transport (GO:0072321) | 2.53909183 |
| 84 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.53852947 |
| 85 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.53725755 |
| 86 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.53013786 |
| 87 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.53013786 |
| 88 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.53013786 |
| 89 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.52615624 |
| 90 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.49301055 |
| 91 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.49301055 |
| 92 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.48618645 |
| 93 | macromolecular complex disassembly (GO:0032984) | 2.46994556 |
| 94 | positive regulation of defense response to virus by host (GO:0002230) | 2.46291084 |
| 95 | UTP biosynthetic process (GO:0006228) | 2.45717002 |
| 96 | axoneme assembly (GO:0035082) | 2.44882426 |
| 97 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.44869610 |
| 98 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.44756197 |
| 99 | cellular component biogenesis (GO:0044085) | 2.44347983 |
| 100 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.43926507 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.20242186 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.97570376 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.44216330 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.20619124 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.16930668 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.68670998 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.64398241 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.59553912 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.29686608 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.28921974 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.26017251 |
| 12 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.15728797 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.13538364 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.11398801 |
| 15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.10198001 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.04991125 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.98284702 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.91740605 |
| 19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.91552993 |
| 20 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.82908629 |
| 21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.74154405 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.74100175 |
| 23 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.73559431 |
| 24 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.70404692 |
| 25 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.68299599 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.68147239 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.64921803 |
| 28 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.64407551 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.63556591 |
| 30 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.58625812 |
| 31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.58061498 |
| 32 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.57568940 |
| 33 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.54747957 |
| 34 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.53842050 |
| 35 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.53842050 |
| 36 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.51942394 |
| 37 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.49267400 |
| 38 | AR_20517297_ChIP-Seq_VCAP_Human | 1.49014707 |
| 39 | GATA3_26560356_Chip-Seq_TH2_Human | 1.45606564 |
| 40 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.44873229 |
| 41 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.42441120 |
| 42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.37734758 |
| 43 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.37470650 |
| 44 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.37295862 |
| 45 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34836074 |
| 46 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.34638352 |
| 47 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.32382573 |
| 48 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.31899727 |
| 49 | FUS_26573619_Chip-Seq_HEK293_Human | 1.31028613 |
| 50 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.30188740 |
| 51 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.29983697 |
| 52 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.28950335 |
| 53 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.27956364 |
| 54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.27664360 |
| 55 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.26869936 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.26244376 |
| 57 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.26244376 |
| 58 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.24672562 |
| 59 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.24278174 |
| 60 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.23907203 |
| 61 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.23166629 |
| 62 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.19333263 |
| 63 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.18661624 |
| 64 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.16837931 |
| 65 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.16795488 |
| 66 | NCOR_22424771_ChIP-Seq_293T_Human | 1.16175171 |
| 67 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15961572 |
| 68 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.15933792 |
| 69 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.15797432 |
| 70 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.13783543 |
| 71 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.12042267 |
| 72 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.10999533 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.10787226 |
| 74 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10064997 |
| 75 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.09960314 |
| 76 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08268144 |
| 77 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.07963610 |
| 78 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.07684426 |
| 79 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07079959 |
| 80 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07079959 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.05568550 |
| 82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.04844504 |
| 83 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.04011422 |
| 84 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.01175979 |
| 85 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.00873394 |
| 86 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.00375757 |
| 87 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99928303 |
| 88 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.98142168 |
| 89 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.98060177 |
| 90 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.97120926 |
| 91 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.96517033 |
| 92 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.96275706 |
| 93 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96113397 |
| 94 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.96013341 |
| 95 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.95882344 |
| 96 | ERA_21632823_ChIP-Seq_H3396_Human | 0.94625236 |
| 97 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.93978889 |
| 98 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.93857200 |
| 99 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93838422 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.91947925 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.08057239 |
| 2 | MP0005671_abnormal_response_to | 3.50711702 |
| 3 | MP0009379_abnormal_foot_pigmentation | 3.35069328 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.61353159 |
| 5 | MP0008872_abnormal_physiological_respon | 2.46508849 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 2.41862380 |
| 7 | MP0003646_muscle_fatigue | 2.34997555 |
| 8 | MP0001873_stomach_inflammation | 2.22315776 |
| 9 | MP0002837_dystrophic_cardiac_calcinosis | 2.20326994 |
| 10 | MP0004147_increased_porphyrin_level | 2.19268270 |
| 11 | MP0009785_altered_susceptibility_to | 2.18296464 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 2.12378414 |
| 13 | MP0006072_abnormal_retinal_apoptosis | 2.11795870 |
| 14 | MP0005645_abnormal_hypothalamus_physiol | 2.10626622 |
| 15 | MP0003195_calcinosis | 2.04717137 |
| 16 | MP0004142_abnormal_muscle_tone | 2.02691756 |
| 17 | MP0000685_abnormal_immune_system | 1.86047009 |
| 18 | MP0000372_irregular_coat_pigmentation | 1.85843593 |
| 19 | MP0005387_immune_system_phenotype | 1.78732480 |
| 20 | MP0001790_abnormal_immune_system | 1.78732480 |
| 21 | MP0004885_abnormal_endolymph | 1.78566277 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.73230747 |
| 23 | MP0002876_abnormal_thyroid_physiology | 1.73156153 |
| 24 | MP0001800_abnormal_humoral_immune | 1.71318800 |
| 25 | MP0006292_abnormal_olfactory_placode | 1.70054081 |
| 26 | MP0002102_abnormal_ear_morphology | 1.63401275 |
| 27 | MP0002166_altered_tumor_susceptibility | 1.62913459 |
| 28 | MP0001986_abnormal_taste_sensitivity | 1.61811961 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.58559864 |
| 30 | MP0004145_abnormal_muscle_electrophysio | 1.58404716 |
| 31 | MP0006036_abnormal_mitochondrial_physio | 1.52770375 |
| 32 | MP0005000_abnormal_immune_tolerance | 1.52323072 |
| 33 | MP0002148_abnormal_hypersensitivity_rea | 1.47157234 |
| 34 | MP0005551_abnormal_eye_electrophysiolog | 1.46259159 |
| 35 | MP0009764_decreased_sensitivity_to | 1.44965856 |
| 36 | MP0002638_abnormal_pupillary_reflex | 1.41759470 |
| 37 | MP0005646_abnormal_pituitary_gland | 1.37843666 |
| 38 | MP0002006_tumorigenesis | 1.34315679 |
| 39 | MP0010386_abnormal_urinary_bladder | 1.34225807 |
| 40 | MP0001919_abnormal_reproductive_system | 1.33700960 |
| 41 | MP0009333_abnormal_splenocyte_physiolog | 1.32272831 |
| 42 | MP0002736_abnormal_nociception_after | 1.31921523 |
| 43 | MP0002723_abnormal_immune_serum | 1.27965566 |
| 44 | MP0003787_abnormal_imprinting | 1.27801117 |
| 45 | MP0002163_abnormal_gland_morphology | 1.25732148 |
| 46 | MP0002138_abnormal_hepatobiliary_system | 1.24832145 |
| 47 | MP0003786_premature_aging | 1.22049148 |
| 48 | MP0005389_reproductive_system_phenotype | 1.19886705 |
| 49 | MP0002272_abnormal_nervous_system | 1.18944700 |
| 50 | MP0005253_abnormal_eye_physiology | 1.18861037 |
| 51 | MP0005360_urolithiasis | 1.17804172 |
| 52 | MP0008995_early_reproductive_senescence | 1.14408727 |
| 53 | MP0002420_abnormal_adaptive_immunity | 1.14079614 |
| 54 | MP0009745_abnormal_behavioral_response | 1.13782865 |
| 55 | MP0005379_endocrine/exocrine_gland_phen | 1.12920929 |
| 56 | MP0002452_abnormal_antigen_presenting | 1.12664643 |
| 57 | MP0001819_abnormal_immune_cell | 1.12012796 |
| 58 | MP0003011_delayed_dark_adaptation | 1.11821452 |
| 59 | MP0001905_abnormal_dopamine_level | 1.09857021 |
| 60 | MP0005636_abnormal_mineral_homeostasis | 1.09409522 |
| 61 | MP0002277_abnormal_respiratory_mucosa | 1.09112977 |
| 62 | MP0001984_abnormal_olfaction | 1.08281537 |
| 63 | MP0002693_abnormal_pancreas_physiology | 1.07638630 |
| 64 | MP0004742_abnormal_vestibular_system | 1.07213825 |
| 65 | MP0001853_heart_inflammation | 1.07188252 |
| 66 | MP0003186_abnormal_redox_activity | 1.06441257 |
| 67 | MP0005084_abnormal_gallbladder_morpholo | 1.03133809 |
| 68 | MP0006082_CNS_inflammation | 1.02169250 |
| 69 | MP0001485_abnormal_pinna_reflex | 1.01374302 |
| 70 | MP0002938_white_spotting | 1.01082069 |
| 71 | MP0010155_abnormal_intestine_physiology | 1.00683446 |
| 72 | MP0001348_abnormal_lacrimal_gland | 1.00412348 |
| 73 | MP0003866_abnormal_defecation | 1.00342329 |
| 74 | MP0005025_abnormal_response_to | 0.98150646 |
| 75 | MP0002234_abnormal_pharynx_morphology | 0.98115660 |
| 76 | MP0001845_abnormal_inflammatory_respons | 0.96929912 |
| 77 | MP0005332_abnormal_amino_acid | 0.95906244 |
| 78 | MP0001501_abnormal_sleep_pattern | 0.95658069 |
| 79 | MP0001765_abnormal_ion_homeostasis | 0.95060130 |
| 80 | MP0005408_hypopigmentation | 0.92105323 |
| 81 | MP0009046_muscle_twitch | 0.90976780 |
| 82 | MP0003763_abnormal_thymus_physiology | 0.90971702 |
| 83 | MP0001970_abnormal_pain_threshold | 0.90859944 |
| 84 | MP0003724_increased_susceptibility_to | 0.90789677 |
| 85 | MP0000631_abnormal_neuroendocrine_gland | 0.86843715 |
| 86 | MP0001764_abnormal_homeostasis | 0.86459355 |
| 87 | MP0005367_renal/urinary_system_phenotyp | 0.84903941 |
| 88 | MP0000516_abnormal_urinary_system | 0.84903941 |
| 89 | MP0004019_abnormal_vitamin_homeostasis | 0.84850449 |
| 90 | MP0005085_abnormal_gallbladder_physiolo | 0.84560593 |
| 91 | MP0003878_abnormal_ear_physiology | 0.83386086 |
| 92 | MP0005377_hearing/vestibular/ear_phenot | 0.83386086 |
| 93 | MP0002160_abnormal_reproductive_system | 0.82260684 |
| 94 | MP0003880_abnormal_central_pattern | 0.78652968 |
| 95 | MP0004381_abnormal_hair_follicle | 0.75447981 |
| 96 | MP0001440_abnormal_grooming_behavior | 0.74629181 |
| 97 | MP0002933_joint_inflammation | 0.74549913 |
| 98 | MP0003436_decreased_susceptibility_to | 0.74527148 |
| 99 | MP0000716_abnormal_immune_system | 0.74365843 |
| 100 | MP0004043_abnormal_pH_regulation | 0.72287446 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.05804010 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.69331385 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.36152369 |
| 4 | Acute encephalopathy (HP:0006846) | 4.32230782 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.28749770 |
| 6 | Increased CSF lactate (HP:0002490) | 4.20403137 |
| 7 | Hepatocellular necrosis (HP:0001404) | 4.15254038 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 4.13663463 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.82892903 |
| 10 | Hepatic necrosis (HP:0002605) | 3.79162343 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.79050005 |
| 12 | IgG deficiency (HP:0004315) | 3.61063443 |
| 13 | Stomatitis (HP:0010280) | 3.54594483 |
| 14 | Congenital, generalized hypertrichosis (HP:0004540) | 3.48148418 |
| 15 | Congenital stationary night blindness (HP:0007642) | 3.32536415 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.21565086 |
| 17 | Cerebral edema (HP:0002181) | 3.15017513 |
| 18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.10647457 |
| 19 | Exertional dyspnea (HP:0002875) | 3.09798344 |
| 20 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.03359817 |
| 21 | Optic disc pallor (HP:0000543) | 3.02191769 |
| 22 | Molar tooth sign on MRI (HP:0002419) | 3.00415296 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 3.00415296 |
| 24 | Increased intramyocellular lipid droplets (HP:0012240) | 2.95364142 |
| 25 | Methylmalonic acidemia (HP:0002912) | 2.86849485 |
| 26 | Pancreatic cysts (HP:0001737) | 2.86635709 |
| 27 | Increased IgM level (HP:0003496) | 2.76238680 |
| 28 | Reticulocytopenia (HP:0001896) | 2.75155582 |
| 29 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.73331393 |
| 30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.67937012 |
| 31 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.67791388 |
| 32 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.67791388 |
| 33 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.60934887 |
| 34 | Aplastic anemia (HP:0001915) | 2.59099821 |
| 35 | Increased serum lactate (HP:0002151) | 2.58211714 |
| 36 | Macrocytic anemia (HP:0001972) | 2.54724060 |
| 37 | Abnormality of urine glucose concentration (HP:0011016) | 2.52240313 |
| 38 | Glycosuria (HP:0003076) | 2.52240313 |
| 39 | Lactic acidosis (HP:0003128) | 2.51015249 |
| 40 | Hypoproteinemia (HP:0003075) | 2.50592861 |
| 41 | Increased muscle lipid content (HP:0009058) | 2.46867521 |
| 42 | Respiratory failure (HP:0002878) | 2.46744521 |
| 43 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.45930622 |
| 44 | Leukodystrophy (HP:0002415) | 2.38603526 |
| 45 | Methylmalonic aciduria (HP:0012120) | 2.28105347 |
| 46 | Lethargy (HP:0001254) | 2.27425266 |
| 47 | Abnormality of the renal cortex (HP:0011035) | 2.27018888 |
| 48 | Nephronophthisis (HP:0000090) | 2.26731011 |
| 49 | Abolished electroretinogram (ERG) (HP:0000550) | 2.21457863 |
| 50 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20826134 |
| 51 | Pancreatic fibrosis (HP:0100732) | 2.20727938 |
| 52 | Abnormal number of erythroid precursors (HP:0012131) | 2.19459061 |
| 53 | Abnormality of B cell number (HP:0010975) | 2.16011482 |
| 54 | Severe combined immunodeficiency (HP:0004430) | 2.13543147 |
| 55 | Attenuation of retinal blood vessels (HP:0007843) | 2.10224959 |
| 56 | Abnormality of renal resorption (HP:0011038) | 2.09846333 |
| 57 | Hyperphosphaturia (HP:0003109) | 2.08450227 |
| 58 | Respiratory difficulties (HP:0002880) | 2.06508727 |
| 59 | Abnormality of vitamin B metabolism (HP:0004340) | 2.05085366 |
| 60 | Thyroiditis (HP:0100646) | 2.04079803 |
| 61 | Pendular nystagmus (HP:0012043) | 2.02625410 |
| 62 | Exercise intolerance (HP:0003546) | 2.02045231 |
| 63 | Type II lissencephaly (HP:0007260) | 2.01964517 |
| 64 | True hermaphroditism (HP:0010459) | 1.99086054 |
| 65 | Constricted visual fields (HP:0001133) | 1.98460122 |
| 66 | Chronic diarrhea (HP:0002028) | 1.98404611 |
| 67 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.95653909 |
| 68 | Decreased central vision (HP:0007663) | 1.94341935 |
| 69 | Medial flaring of the eyebrow (HP:0010747) | 1.92543295 |
| 70 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.91461324 |
| 71 | Abnormality of the renal medulla (HP:0100957) | 1.89284294 |
| 72 | Hypoplasia of the ulna (HP:0003022) | 1.87394460 |
| 73 | Renal cortical cysts (HP:0000803) | 1.85968454 |
| 74 | Abnormality of the prostate (HP:0008775) | 1.85748921 |
| 75 | B lymphocytopenia (HP:0010976) | 1.84833498 |
| 76 | Hypothermia (HP:0002045) | 1.81266234 |
| 77 | Abnormal albumin level (HP:0012116) | 1.81165239 |
| 78 | Hypoalbuminemia (HP:0003073) | 1.81165239 |
| 79 | Septo-optic dysplasia (HP:0100842) | 1.81115082 |
| 80 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.80902346 |
| 81 | Sclerocornea (HP:0000647) | 1.79394274 |
| 82 | Abnormality of T cells (HP:0002843) | 1.79195076 |
| 83 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.77950129 |
| 84 | Dicarboxylic aciduria (HP:0003215) | 1.77950129 |
| 85 | Testicular atrophy (HP:0000029) | 1.77014773 |
| 86 | Absent thumb (HP:0009777) | 1.76477227 |
| 87 | Hypoplasia of the uterus (HP:0000013) | 1.76206038 |
| 88 | Pancytopenia (HP:0001876) | 1.75732333 |
| 89 | Pallor (HP:0000980) | 1.75656529 |
| 90 | X-linked dominant inheritance (HP:0001423) | 1.73616873 |
| 91 | Ketosis (HP:0001946) | 1.73168130 |
| 92 | Abnormality of T cell number (HP:0011839) | 1.72350772 |
| 93 | Hypomagnesemia (HP:0002917) | 1.71961449 |
| 94 | Hyperglycinemia (HP:0002154) | 1.71525362 |
| 95 | Type 2 muscle fiber atrophy (HP:0003554) | 1.71301473 |
| 96 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.71031754 |
| 97 | Abnormality of DNA repair (HP:0003254) | 1.70747324 |
| 98 | Polydipsia (HP:0001959) | 1.69383206 |
| 99 | Abnormal drinking behavior (HP:0030082) | 1.69383206 |
| 100 | Abnormality of T cell physiology (HP:0011840) | 1.69218761 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.05257517 |
| 2 | ADRBK2 | 2.84775293 |
| 3 | TLK1 | 2.80847602 |
| 4 | FRK | 2.79511112 |
| 5 | ZAK | 2.79495195 |
| 6 | MAP3K12 | 2.77083734 |
| 7 | GRK1 | 2.71414258 |
| 8 | MAP4K2 | 2.59189891 |
| 9 | CDK19 | 2.52650208 |
| 10 | NUAK1 | 2.40345978 |
| 11 | PINK1 | 2.37095036 |
| 12 | VRK2 | 2.19262608 |
| 13 | MAP4K1 | 2.09185812 |
| 14 | NME1 | 2.03650004 |
| 15 | EIF2AK3 | 1.92028387 |
| 16 | WNK4 | 1.87365813 |
| 17 | TAOK3 | 1.80475631 |
| 18 | MST4 | 1.77324363 |
| 19 | PASK | 1.73101805 |
| 20 | TEC | 1.73061728 |
| 21 | OXSR1 | 1.73060047 |
| 22 | MYLK | 1.72437198 |
| 23 | KDR | 1.56816973 |
| 24 | ITK | 1.50950642 |
| 25 | CAMKK2 | 1.46449181 |
| 26 | WNK3 | 1.40078283 |
| 27 | TIE1 | 1.38834613 |
| 28 | EIF2AK1 | 1.31075153 |
| 29 | VRK1 | 1.20431300 |
| 30 | BCKDK | 1.19309175 |
| 31 | IKBKB | 1.18860202 |
| 32 | TRIM28 | 1.16498426 |
| 33 | BMPR2 | 1.16375358 |
| 34 | INSRR | 1.14989022 |
| 35 | MUSK | 1.14568908 |
| 36 | MAP2K6 | 1.13296319 |
| 37 | STK16 | 1.09861538 |
| 38 | PHKG1 | 1.08941207 |
| 39 | PHKG2 | 1.08941207 |
| 40 | BMPR1B | 1.07689055 |
| 41 | STK39 | 1.05291592 |
| 42 | KIT | 1.03789294 |
| 43 | BTK | 0.98457205 |
| 44 | DYRK2 | 0.98142250 |
| 45 | DAPK2 | 0.93875504 |
| 46 | PIK3CA | 0.93775500 |
| 47 | PAK3 | 0.86095394 |
| 48 | ERBB3 | 0.83661383 |
| 49 | SCYL2 | 0.82251626 |
| 50 | DAPK1 | 0.81455806 |
| 51 | CSF1R | 0.80962315 |
| 52 | LYN | 0.80189116 |
| 53 | MAP3K4 | 0.79710851 |
| 54 | SYK | 0.79233519 |
| 55 | PLK4 | 0.78166290 |
| 56 | PRKCQ | 0.71021982 |
| 57 | DAPK3 | 0.70677096 |
| 58 | CSNK1G3 | 0.68426235 |
| 59 | EIF2AK2 | 0.66472253 |
| 60 | OBSCN | 0.66332752 |
| 61 | FLT3 | 0.65410953 |
| 62 | RPS6KA5 | 0.64511797 |
| 63 | CSNK1G2 | 0.62764221 |
| 64 | ADRBK1 | 0.62639364 |
| 65 | GRK6 | 0.61752365 |
| 66 | CSNK1G1 | 0.59259858 |
| 67 | CAMKK1 | 0.58599253 |
| 68 | NEK1 | 0.57455888 |
| 69 | PRKCE | 0.56621788 |
| 70 | ILK | 0.54968813 |
| 71 | LCK | 0.54682963 |
| 72 | PRKACA | 0.52719184 |
| 73 | FES | 0.52714005 |
| 74 | PRKCG | 0.52307666 |
| 75 | NLK | 0.49872018 |
| 76 | CSNK2A2 | 0.49672685 |
| 77 | IGF1R | 0.49123607 |
| 78 | PRKCA | 0.48650243 |
| 79 | LRRK2 | 0.47504149 |
| 80 | CSNK1A1L | 0.46194034 |
| 81 | PIK3CG | 0.45222154 |
| 82 | NME2 | 0.44589914 |
| 83 | CSNK1A1 | 0.44265629 |
| 84 | ACVR1B | 0.43848857 |
| 85 | CSNK2A1 | 0.42412553 |
| 86 | ERBB2 | 0.40806082 |
| 87 | CAMK2A | 0.40564473 |
| 88 | PLK3 | 0.38894450 |
| 89 | MAPK13 | 0.37385202 |
| 90 | MAP2K7 | 0.36738942 |
| 91 | BUB1 | 0.36622855 |
| 92 | PDK2 | 0.35529150 |
| 93 | CAMK2D | 0.35215130 |
| 94 | MAP3K11 | 0.34562260 |
| 95 | ROCK1 | 0.33656509 |
| 96 | MKNK2 | 0.32759118 |
| 97 | ABL1 | 0.31601988 |
| 98 | AURKB | 0.30462041 |
| 99 | PRKG1 | 0.30136614 |
| 100 | PLK2 | 0.29766446 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.05284029 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.88625885 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.83076780 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.31300405 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.16762920 |
| 6 | Protein export_Homo sapiens_hsa03060 | 3.15271892 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 3.14062068 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.00447902 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.88670889 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.66054350 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.54553466 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.09967112 |
| 13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.05568435 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.97000668 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.96976954 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.94857937 |
| 17 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.94474532 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 1.88289432 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.59843419 |
| 20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.56647380 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.42629238 |
| 22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.40104492 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.39636468 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.33847163 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.29588721 |
| 26 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.23025504 |
| 27 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.22193276 |
| 28 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.20632691 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.19752922 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.15165752 |
| 31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.12716899 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.08915248 |
| 33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.07516438 |
| 34 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.03751105 |
| 35 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.01082267 |
| 36 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.99316612 |
| 37 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.98836317 |
| 38 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.97247839 |
| 39 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.93885749 |
| 40 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.93261261 |
| 41 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.91760475 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.90713667 |
| 43 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.90471406 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.85666566 |
| 45 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.84469133 |
| 46 | Viral myocarditis_Homo sapiens_hsa05416 | 0.84010676 |
| 47 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.79316843 |
| 48 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.77294350 |
| 49 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.75238214 |
| 50 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.72762061 |
| 51 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.71800820 |
| 52 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.70696803 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.69393011 |
| 54 | Retinol metabolism_Homo sapiens_hsa00830 | 0.67479619 |
| 55 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.65896827 |
| 56 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.65681654 |
| 57 | Peroxisome_Homo sapiens_hsa04146 | 0.65464855 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65160074 |
| 59 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.64555368 |
| 60 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.63812570 |
| 61 | Purine metabolism_Homo sapiens_hsa00230 | 0.63112977 |
| 62 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.62050872 |
| 63 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.61601892 |
| 64 | Mismatch repair_Homo sapiens_hsa03430 | 0.60618116 |
| 65 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59867374 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57685448 |
| 67 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57158506 |
| 68 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.56651158 |
| 69 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.56033865 |
| 70 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55728909 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55479955 |
| 72 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55106401 |
| 73 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.54361908 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53828165 |
| 75 | Nicotine addiction_Homo sapiens_hsa05033 | 0.49822547 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46415907 |
| 77 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.46065199 |
| 78 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.45962254 |
| 79 | RNA transport_Homo sapiens_hsa03013 | 0.45476347 |
| 80 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.44904467 |
| 81 | Mineral absorption_Homo sapiens_hsa04978 | 0.40621958 |
| 82 | Spliceosome_Homo sapiens_hsa03040 | 0.40224252 |
| 83 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.37736649 |
| 84 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.37547444 |
| 85 | Taste transduction_Homo sapiens_hsa04742 | 0.37032978 |
| 86 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32828190 |
| 87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.28467152 |
| 88 | Leishmaniasis_Homo sapiens_hsa05140 | 0.28288648 |
| 89 | Morphine addiction_Homo sapiens_hsa05032 | 0.27714046 |
| 90 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.27324246 |
| 91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.26355454 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.25640895 |
| 93 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.24878635 |
| 94 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.23237246 |
| 95 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.20618472 |
| 96 | DNA replication_Homo sapiens_hsa03030 | 0.19445306 |
| 97 | Malaria_Homo sapiens_hsa05144 | 0.18570398 |
| 98 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.16605631 |
| 99 | Sulfur relay system_Homo sapiens_hsa04122 | 0.16311052 |
| 100 | GABAergic synapse_Homo sapiens_hsa04727 | 0.15107294 |

