

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal large subunit biogenesis (GO:0042273) | 5.70706949 |
| 2 | termination of RNA polymerase III transcription (GO:0006386) | 5.55403227 |
| 3 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 5.55403227 |
| 4 | positive regulation of interleukin-17 production (GO:0032740) | 5.03158454 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.92905915 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.70190578 |
| 7 | ATP synthesis coupled proton transport (GO:0015986) | 4.70190578 |
| 8 | protein complex biogenesis (GO:0070271) | 4.69160814 |
| 9 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.57289260 |
| 10 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.57289260 |
| 11 | protein localization to cilium (GO:0061512) | 4.53633123 |
| 12 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.49316246 |
| 13 | NADH dehydrogenase complex assembly (GO:0010257) | 4.49316246 |
| 14 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.49316246 |
| 15 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 4.40137305 |
| 16 | regulation of regulatory T cell differentiation (GO:0045589) | 4.38341135 |
| 17 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 4.26917985 |
| 18 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.26788994 |
| 19 | regulation of T cell tolerance induction (GO:0002664) | 4.23209625 |
| 20 | regulation of cellular respiration (GO:0043457) | 4.10531108 |
| 21 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.06076625 |
| 22 | positive regulation of activated T cell proliferation (GO:0042104) | 4.01293218 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.01100971 |
| 24 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.93908353 |
| 25 | cotranslational protein targeting to membrane (GO:0006613) | 3.83531777 |
| 26 | termination of RNA polymerase I transcription (GO:0006363) | 3.81493694 |
| 27 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.76892702 |
| 28 | protein targeting to ER (GO:0045047) | 3.76817413 |
| 29 | proteasome assembly (GO:0043248) | 3.71807312 |
| 30 | myeloid dendritic cell activation (GO:0001773) | 3.70667171 |
| 31 | protein localization to endoplasmic reticulum (GO:0070972) | 3.69091749 |
| 32 | myeloid dendritic cell differentiation (GO:0043011) | 3.68062139 |
| 33 | aldehyde catabolic process (GO:0046185) | 3.67334847 |
| 34 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.66549823 |
| 35 | positive regulation of type 2 immune response (GO:0002830) | 3.65785685 |
| 36 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.64554578 |
| 37 | platelet dense granule organization (GO:0060155) | 3.59392462 |
| 38 | positive regulation of isotype switching (GO:0045830) | 3.58009404 |
| 39 | DNA deamination (GO:0045006) | 3.56630651 |
| 40 | respiratory electron transport chain (GO:0022904) | 3.53638740 |
| 41 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.53115630 |
| 42 | regulation of tolerance induction (GO:0002643) | 3.51315257 |
| 43 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.50975501 |
| 44 | electron transport chain (GO:0022900) | 3.48486743 |
| 45 | positive regulation of DNA recombination (GO:0045911) | 3.47555010 |
| 46 | purine-containing compound salvage (GO:0043101) | 3.45968645 |
| 47 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.39453689 |
| 48 | viral transcription (GO:0019083) | 3.39054608 |
| 49 | translational termination (GO:0006415) | 3.38057604 |
| 50 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 3.35885454 |
| 51 | mismatch repair (GO:0006298) | 3.31054879 |
| 52 | viral protein processing (GO:0019082) | 3.27300972 |
| 53 | regulation of activated T cell proliferation (GO:0046006) | 3.16718876 |
| 54 | centriole replication (GO:0007099) | 3.14806708 |
| 55 | rRNA modification (GO:0000154) | 3.10625142 |
| 56 | respiratory chain complex IV assembly (GO:0008535) | 3.08742546 |
| 57 | translation (GO:0006412) | 3.07201680 |
| 58 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.06816019 |
| 59 | translational elongation (GO:0006414) | 3.06722112 |
| 60 | regulation of interleukin-17 production (GO:0032660) | 3.05675921 |
| 61 | positive regulation of T-helper cell differentiation (GO:0045624) | 3.04060883 |
| 62 | membrane budding (GO:0006900) | 3.02412406 |
| 63 | signal peptide processing (GO:0006465) | 3.01957933 |
| 64 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.01873248 |
| 65 | mitochondrial fragmentation involved in apoptotic process (GO:0043653) | 3.01668598 |
| 66 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.98598739 |
| 67 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.95965698 |
| 68 | positive regulation of T cell proliferation (GO:0042102) | 2.95027017 |
| 69 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.94219413 |
| 70 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.93637703 |
| 71 | negative regulation of mast cell activation (GO:0033004) | 2.92371644 |
| 72 | cytochrome complex assembly (GO:0017004) | 2.91011147 |
| 73 | transcription from RNA polymerase I promoter (GO:0006360) | 2.89836245 |
| 74 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.88454880 |
| 75 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.88454880 |
| 76 | regulation of immunoglobulin secretion (GO:0051023) | 2.87451728 |
| 77 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.86356184 |
| 78 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.86356184 |
| 79 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.86356184 |
| 80 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.86287730 |
| 81 | anterograde synaptic vesicle transport (GO:0048490) | 2.86113233 |
| 82 | negative regulation of B cell apoptotic process (GO:0002903) | 2.86088372 |
| 83 | tryptophan catabolic process (GO:0006569) | 2.85002791 |
| 84 | indole-containing compound catabolic process (GO:0042436) | 2.85002791 |
| 85 | indolalkylamine catabolic process (GO:0046218) | 2.85002791 |
| 86 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.84109990 |
| 87 | T cell costimulation (GO:0031295) | 2.83752986 |
| 88 | rRNA methylation (GO:0031167) | 2.83604213 |
| 89 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.83493506 |
| 90 | lymphocyte costimulation (GO:0031294) | 2.80775601 |
| 91 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.80152353 |
| 92 | cytokine biosynthetic process (GO:0042089) | 2.79335553 |
| 93 | positive regulation of B cell mediated immunity (GO:0002714) | 2.78006392 |
| 94 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 2.78006392 |
| 95 | nucleobase biosynthetic process (GO:0046112) | 2.77721165 |
| 96 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.75153613 |
| 97 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.73681743 |
| 98 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.73681743 |
| 99 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.68516235 |
| 100 | G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589) | 2.67896398 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.81533378 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.67378619 |
| 3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.26236405 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.03214313 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.02599553 |
| 6 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.91937499 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.83174637 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.80559195 |
| 9 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.57586043 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.55148705 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.50305720 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.48505472 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.36285302 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.32889111 |
| 15 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.30133640 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.28417359 |
| 17 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.24238433 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.24054582 |
| 19 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.20981267 |
| 20 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.09988295 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.02370894 |
| 22 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.98602431 |
| 23 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.97752497 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.91766089 |
| 25 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.84820880 |
| 26 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.79789216 |
| 27 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.70935637 |
| 28 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.70247773 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.67973171 |
| 30 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.62466814 |
| 31 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.61447118 |
| 32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.59238613 |
| 33 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.58399338 |
| 34 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.58399338 |
| 35 | GATA3_26560356_Chip-Seq_TH2_Human | 1.53170119 |
| 36 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.50898578 |
| 37 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.50831962 |
| 38 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.48861935 |
| 39 | EWS_26573619_Chip-Seq_HEK293_Human | 1.48185401 |
| 40 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.47031373 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44201245 |
| 42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42561091 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42096440 |
| 44 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.39163793 |
| 45 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.36841075 |
| 46 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.36841075 |
| 47 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.35108577 |
| 48 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.34559100 |
| 49 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.34153337 |
| 50 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.33470621 |
| 51 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.32911393 |
| 52 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.32713689 |
| 53 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.30120635 |
| 54 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.29981375 |
| 55 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.29705200 |
| 56 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.28911927 |
| 57 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.27706538 |
| 58 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.26797705 |
| 59 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.26766569 |
| 60 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.24080656 |
| 61 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.23863072 |
| 62 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.23337756 |
| 63 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.22911915 |
| 64 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.20071298 |
| 65 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.18839111 |
| 66 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.18411123 |
| 67 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.17496727 |
| 68 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.16795167 |
| 69 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.16376715 |
| 70 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.15782521 |
| 71 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.12019040 |
| 72 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.11924168 |
| 73 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.11520637 |
| 74 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.11170488 |
| 75 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.10070599 |
| 76 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.09849568 |
| 77 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.09849568 |
| 78 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.09641727 |
| 79 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.09132134 |
| 80 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.08567592 |
| 81 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.08165150 |
| 82 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.07973205 |
| 83 | FUS_26573619_Chip-Seq_HEK293_Human | 1.07740145 |
| 84 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.07606486 |
| 85 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.07017864 |
| 86 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.06583572 |
| 87 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.06218937 |
| 88 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.04744867 |
| 89 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.04315695 |
| 90 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.04179506 |
| 91 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.03599417 |
| 92 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.02602902 |
| 93 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.01703842 |
| 94 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.01185539 |
| 95 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00855706 |
| 96 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.98801461 |
| 97 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.98388187 |
| 98 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.97574376 |
| 99 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.97007065 |
| 100 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.96986604 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 7.22161403 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 3.60316566 |
| 3 | MP0004142_abnormal_muscle_tone | 3.08162002 |
| 4 | MP0005671_abnormal_response_to | 2.98764704 |
| 5 | MP0004147_increased_porphyrin_level | 2.85930986 |
| 6 | MP0001529_abnormal_vocalization | 2.81293682 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.60121681 |
| 8 | MP0002837_dystrophic_cardiac_calcinosis | 2.57980152 |
| 9 | MP0003186_abnormal_redox_activity | 2.28722726 |
| 10 | MP0005387_immune_system_phenotype | 2.12636842 |
| 11 | MP0001790_abnormal_immune_system | 2.12636842 |
| 12 | MP0001800_abnormal_humoral_immune | 2.12581045 |
| 13 | MP0003172_abnormal_lysosome_physiology | 2.10916624 |
| 14 | MP0001853_heart_inflammation | 2.06351532 |
| 15 | MP0008875_abnormal_xenobiotic_pharmacok | 2.04104392 |
| 16 | MP0009785_altered_susceptibility_to | 1.98612049 |
| 17 | MP0002138_abnormal_hepatobiliary_system | 1.96437011 |
| 18 | MP0005670_abnormal_white_adipose | 1.94115210 |
| 19 | MP0002163_abnormal_gland_morphology | 1.93695715 |
| 20 | MP0008872_abnormal_physiological_respon | 1.91551533 |
| 21 | MP0002148_abnormal_hypersensitivity_rea | 1.87531681 |
| 22 | MP0001440_abnormal_grooming_behavior | 1.85477721 |
| 23 | MP0000465_gastrointestinal_hemorrhage | 1.80014248 |
| 24 | MP0006036_abnormal_mitochondrial_physio | 1.79652858 |
| 25 | MP0002166_altered_tumor_susceptibility | 1.77056970 |
| 26 | MP0001905_abnormal_dopamine_level | 1.74983053 |
| 27 | MP0001873_stomach_inflammation | 1.69514292 |
| 28 | MP0003567_abnormal_fetal_cardiomyocyte | 1.64102918 |
| 29 | MP0003300_gastrointestinal_ulcer | 1.53538831 |
| 30 | MP0002452_abnormal_antigen_presenting | 1.48730346 |
| 31 | MP0005000_abnormal_immune_tolerance | 1.47787118 |
| 32 | MP0005645_abnormal_hypothalamus_physiol | 1.41446977 |
| 33 | MP0005379_endocrine/exocrine_gland_phen | 1.38296995 |
| 34 | MP0006082_CNS_inflammation | 1.37492785 |
| 35 | MP0004215_abnormal_myocardial_fiber | 1.36924707 |
| 36 | MP0003183_abnormal_peptide_metabolism | 1.35305818 |
| 37 | MP0003195_calcinosis | 1.34606991 |
| 38 | MP0003866_abnormal_defecation | 1.32862610 |
| 39 | MP0003724_increased_susceptibility_to | 1.31958322 |
| 40 | MP0001984_abnormal_olfaction | 1.31755449 |
| 41 | MP0002723_abnormal_immune_serum | 1.30966776 |
| 42 | MP0003763_abnormal_thymus_physiology | 1.29126091 |
| 43 | MP0010155_abnormal_intestine_physiology | 1.28772020 |
| 44 | MP0002090_abnormal_vision | 1.28414214 |
| 45 | MP0004782_abnormal_surfactant_physiolog | 1.26695090 |
| 46 | MP0005084_abnormal_gallbladder_morpholo | 1.22625442 |
| 47 | MP0002006_tumorigenesis | 1.22207962 |
| 48 | MP0006292_abnormal_olfactory_placode | 1.22026971 |
| 49 | MP0003137_abnormal_impulse_conducting | 1.19809095 |
| 50 | MP0010386_abnormal_urinary_bladder | 1.19396091 |
| 51 | MP0006072_abnormal_retinal_apoptosis | 1.18821215 |
| 52 | MP0005408_hypopigmentation | 1.13971946 |
| 53 | MP0005367_renal/urinary_system_phenotyp | 1.12196162 |
| 54 | MP0000516_abnormal_urinary_system | 1.12196162 |
| 55 | MP0001819_abnormal_immune_cell | 1.11034445 |
| 56 | MP0005075_abnormal_melanosome_morpholog | 1.07186051 |
| 57 | MP0001485_abnormal_pinna_reflex | 1.05760870 |
| 58 | MP0000685_abnormal_immune_system | 1.05621782 |
| 59 | MP0005636_abnormal_mineral_homeostasis | 1.05567031 |
| 60 | MP0000013_abnormal_adipose_tissue | 1.03179520 |
| 61 | MP0005332_abnormal_amino_acid | 1.02752229 |
| 62 | MP0002420_abnormal_adaptive_immunity | 1.00310928 |
| 63 | MP0002693_abnormal_pancreas_physiology | 0.97633886 |
| 64 | MP0005025_abnormal_response_to | 0.96863624 |
| 65 | MP0006035_abnormal_mitochondrial_morpho | 0.94309065 |
| 66 | MP0001968_abnormal_touch/_nociception | 0.94152286 |
| 67 | MP0001845_abnormal_inflammatory_respons | 0.92699425 |
| 68 | MP0009333_abnormal_splenocyte_physiolog | 0.91084007 |
| 69 | MP0002102_abnormal_ear_morphology | 0.90348384 |
| 70 | MP0002751_abnormal_autonomic_nervous | 0.89513664 |
| 71 | MP0002736_abnormal_nociception_after | 0.89362563 |
| 72 | MP0000538_abnormal_urinary_bladder | 0.89278262 |
| 73 | MP0002254_reproductive_system_inflammat | 0.88858669 |
| 74 | MP0005551_abnormal_eye_electrophysiolog | 0.88023569 |
| 75 | MP0002234_abnormal_pharynx_morphology | 0.85536753 |
| 76 | MP0008469_abnormal_protein_level | 0.82934245 |
| 77 | MP0001486_abnormal_startle_reflex | 0.82372057 |
| 78 | MP0005389_reproductive_system_phenotype | 0.80561992 |
| 79 | MP0009697_abnormal_copulation | 0.80408873 |
| 80 | MP0000716_abnormal_immune_system | 0.78588539 |
| 81 | MP0005253_abnormal_eye_physiology | 0.78095566 |
| 82 | MP0003718_maternal_effect | 0.77341454 |
| 83 | MP0000639_abnormal_adrenal_gland | 0.77248858 |
| 84 | MP0005377_hearing/vestibular/ear_phenot | 0.76836818 |
| 85 | MP0003878_abnormal_ear_physiology | 0.76836818 |
| 86 | MP0002398_abnormal_bone_marrow | 0.76650490 |
| 87 | MP0009643_abnormal_urine_homeostasis | 0.72881663 |
| 88 | MP0005535_abnormal_body_temperature | 0.71672433 |
| 89 | MP0005646_abnormal_pituitary_gland | 0.71536681 |
| 90 | MP0003638_abnormal_response/metabolism_ | 0.70724698 |
| 91 | MP0001756_abnormal_urination | 0.67591719 |
| 92 | MP0001970_abnormal_pain_threshold | 0.66528390 |
| 93 | MP0009745_abnormal_behavioral_response | 0.64669226 |
| 94 | MP0003283_abnormal_digestive_organ | 0.63295721 |
| 95 | MP0009764_decreased_sensitivity_to | 0.62516290 |
| 96 | MP0003011_delayed_dark_adaptation | 0.61101167 |
| 97 | MP0004085_abnormal_heartbeat | 0.60821736 |
| 98 | MP0002429_abnormal_blood_cell | 0.60425950 |
| 99 | MP0002272_abnormal_nervous_system | 0.60257935 |
| 100 | MP0000371_diluted_coat_color | 0.59723677 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hepatocellular necrosis (HP:0001404) | 6.51051570 |
| 2 | Multiple enchondromatosis (HP:0005701) | 5.76382824 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 5.67727131 |
| 4 | Hepatic necrosis (HP:0002605) | 5.61045405 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.36346116 |
| 6 | Progressive macrocephaly (HP:0004481) | 5.19774376 |
| 7 | Mitochondrial inheritance (HP:0001427) | 4.76040318 |
| 8 | Acute encephalopathy (HP:0006846) | 4.52744918 |
| 9 | Increased CSF lactate (HP:0002490) | 4.17944474 |
| 10 | Cleft eyelid (HP:0000625) | 3.93688504 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.55189411 |
| 12 | Leukodystrophy (HP:0002415) | 3.50736931 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.46642487 |
| 14 | Hypoproteinemia (HP:0003075) | 3.33527199 |
| 15 | Aplastic anemia (HP:0001915) | 3.26112259 |
| 16 | Cerebral edema (HP:0002181) | 3.18687344 |
| 17 | Cerebral palsy (HP:0100021) | 3.18525585 |
| 18 | Respiratory failure (HP:0002878) | 3.08668206 |
| 19 | IgG deficiency (HP:0004315) | 3.07794810 |
| 20 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.03976453 |
| 21 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.94405259 |
| 22 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.94405259 |
| 23 | Split foot (HP:0001839) | 2.93538696 |
| 24 | Congenital, generalized hypertrichosis (HP:0004540) | 2.81377304 |
| 25 | Chronic diarrhea (HP:0002028) | 2.77449831 |
| 26 | Increased IgM level (HP:0003496) | 2.75848784 |
| 27 | Obstructive lung disease (HP:0006536) | 2.72131779 |
| 28 | Chronic obstructive pulmonary disease (HP:0006510) | 2.72131779 |
| 29 | Trismus (HP:0000211) | 2.71401560 |
| 30 | Methylmalonic aciduria (HP:0012120) | 2.69563072 |
| 31 | Type II lissencephaly (HP:0007260) | 2.62898971 |
| 32 | Hemoptysis (HP:0002105) | 2.61587497 |
| 33 | Median cleft lip (HP:0000161) | 2.59951587 |
| 34 | Optic disc pallor (HP:0000543) | 2.56314036 |
| 35 | Spastic paraparesis (HP:0002313) | 2.55402180 |
| 36 | Glossoptosis (HP:0000162) | 2.55091916 |
| 37 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.44994325 |
| 38 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.44387570 |
| 39 | Hypoplasia of the pons (HP:0012110) | 2.42921560 |
| 40 | CNS demyelination (HP:0007305) | 2.37138053 |
| 41 | Abolished electroretinogram (ERG) (HP:0000550) | 2.36571032 |
| 42 | B lymphocytopenia (HP:0010976) | 2.36239962 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.33588227 |
| 44 | Macrocytic anemia (HP:0001972) | 2.33143959 |
| 45 | Increased serum lactate (HP:0002151) | 2.31274407 |
| 46 | Flat occiput (HP:0005469) | 2.31011249 |
| 47 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.27763344 |
| 48 | Vasculitis (HP:0002633) | 2.27471670 |
| 49 | Hypoplasia of the uterus (HP:0000013) | 2.26211474 |
| 50 | Abnormality of the pleura (HP:0002103) | 2.24257494 |
| 51 | Abnormality of the pons (HP:0007361) | 2.19708771 |
| 52 | Abnormality of vitamin B metabolism (HP:0004340) | 2.19588032 |
| 53 | Global brain atrophy (HP:0002283) | 2.19225534 |
| 54 | Stomatitis (HP:0010280) | 2.18815973 |
| 55 | Hypoglycemic seizures (HP:0002173) | 2.17613430 |
| 56 | Exercise intolerance (HP:0003546) | 2.16365670 |
| 57 | Thyroiditis (HP:0100646) | 2.12610414 |
| 58 | Cerebellar dysplasia (HP:0007033) | 2.11772137 |
| 59 | Abnormality of methionine metabolism (HP:0010901) | 2.10384187 |
| 60 | Tetany (HP:0001281) | 2.07485080 |
| 61 | Lactic acidosis (HP:0003128) | 2.06017007 |
| 62 | Severe combined immunodeficiency (HP:0004430) | 2.04435047 |
| 63 | Hypoalbuminemia (HP:0003073) | 2.03306640 |
| 64 | Abnormal albumin level (HP:0012116) | 2.03306640 |
| 65 | Porencephaly (HP:0002132) | 2.02576173 |
| 66 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.00329978 |
| 67 | Hypomagnesemia (HP:0002917) | 1.98218615 |
| 68 | Increased hepatocellular lipid droplets (HP:0006565) | 1.94008938 |
| 69 | Stenosis of the external auditory canal (HP:0000402) | 1.93510441 |
| 70 | Emotional lability (HP:0000712) | 1.93336178 |
| 71 | Abnormality of B cell number (HP:0010975) | 1.93229353 |
| 72 | Facial cleft (HP:0002006) | 1.92099991 |
| 73 | Homocystinuria (HP:0002156) | 1.89637454 |
| 74 | Abnormality of homocysteine metabolism (HP:0010919) | 1.89637454 |
| 75 | Female pseudohermaphroditism (HP:0010458) | 1.89200342 |
| 76 | X-linked dominant inheritance (HP:0001423) | 1.89192020 |
| 77 | Sensory axonal neuropathy (HP:0003390) | 1.88125506 |
| 78 | Acute hepatic failure (HP:0006554) | 1.87654259 |
| 79 | Abnormal cartilage morphology (HP:0002763) | 1.86720478 |
| 80 | Hypothermia (HP:0002045) | 1.86625713 |
| 81 | Abnormality of lateral ventricle (HP:0030047) | 1.85912817 |
| 82 | Lipid accumulation in hepatocytes (HP:0006561) | 1.85819445 |
| 83 | Pancytopenia (HP:0001876) | 1.85544118 |
| 84 | Recurrent cutaneous fungal infections (HP:0011370) | 1.85233063 |
| 85 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.85233063 |
| 86 | Choanal stenosis (HP:0000452) | 1.84238173 |
| 87 | Pulmonary infiltrates (HP:0002113) | 1.81604358 |
| 88 | Pulmonary fibrosis (HP:0002206) | 1.79940172 |
| 89 | Genetic anticipation (HP:0003743) | 1.79748318 |
| 90 | Gliosis (HP:0002171) | 1.78411539 |
| 91 | Lethargy (HP:0001254) | 1.78186072 |
| 92 | Molar tooth sign on MRI (HP:0002419) | 1.77295898 |
| 93 | Abnormality of midbrain morphology (HP:0002418) | 1.77295898 |
| 94 | Increased intramyocellular lipid droplets (HP:0012240) | 1.76682116 |
| 95 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.75834343 |
| 96 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.75351757 |
| 97 | Dicarboxylic aciduria (HP:0003215) | 1.75351757 |
| 98 | Abnormal hemoglobin (HP:0011902) | 1.75165758 |
| 99 | Polyneuropathy (HP:0001271) | 1.74489093 |
| 100 | Blindness (HP:0000618) | 1.74129942 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K13 | 5.09382439 |
| 2 | SCYL2 | 4.99391315 |
| 3 | TXK | 4.30135988 |
| 4 | MST4 | 3.97796809 |
| 5 | MAP4K1 | 3.11421019 |
| 6 | MAP3K12 | 2.94040856 |
| 7 | FRK | 2.75829065 |
| 8 | EIF2AK1 | 2.65101352 |
| 9 | MAP3K14 | 2.48220970 |
| 10 | BMPR2 | 2.33734754 |
| 11 | NEK1 | 2.09396307 |
| 12 | EIF2AK3 | 2.03234866 |
| 13 | FES | 1.88015361 |
| 14 | TSSK6 | 1.85718277 |
| 15 | TRIM28 | 1.78498742 |
| 16 | PRKG2 | 1.71234166 |
| 17 | MYLK | 1.67753463 |
| 18 | TLK1 | 1.61084351 |
| 19 | NEK9 | 1.57281057 |
| 20 | NME2 | 1.53649062 |
| 21 | IKBKB | 1.51991611 |
| 22 | ADRBK2 | 1.47121268 |
| 23 | GRK1 | 1.37953637 |
| 24 | FLT3 | 1.22156690 |
| 25 | NUAK1 | 1.19044220 |
| 26 | PIK3CA | 1.17253890 |
| 27 | ILK | 1.14272975 |
| 28 | TEC | 1.09557676 |
| 29 | INSRR | 0.99447828 |
| 30 | RPS6KA4 | 0.97983541 |
| 31 | KIT | 0.97422498 |
| 32 | WNK3 | 0.97153154 |
| 33 | RIPK4 | 0.95233732 |
| 34 | CSNK1G1 | 0.93809919 |
| 35 | TYK2 | 0.93163852 |
| 36 | ITK | 0.93009516 |
| 37 | CSNK1A1L | 0.91760949 |
| 38 | CDK3 | 0.91683124 |
| 39 | OXSR1 | 0.90464751 |
| 40 | CSF1R | 0.89892882 |
| 41 | CSNK1G3 | 0.89414049 |
| 42 | LYN | 0.87939898 |
| 43 | ZAK | 0.87615073 |
| 44 | PASK | 0.86416366 |
| 45 | PIK3CG | 0.84371966 |
| 46 | PAK4 | 0.83072054 |
| 47 | ZAP70 | 0.82679665 |
| 48 | IKBKE | 0.81355973 |
| 49 | MAP2K6 | 0.81343766 |
| 50 | CSNK1G2 | 0.74762674 |
| 51 | SYK | 0.74437883 |
| 52 | CSK | 0.72934841 |
| 53 | PRKCE | 0.72690108 |
| 54 | PRKCQ | 0.70852533 |
| 55 | OBSCN | 0.69924572 |
| 56 | PNCK | 0.66556890 |
| 57 | CDK19 | 0.66253650 |
| 58 | MAP4K2 | 0.66196941 |
| 59 | MAP3K4 | 0.64902254 |
| 60 | RPS6KA5 | 0.63785034 |
| 61 | DAPK1 | 0.63115037 |
| 62 | DYRK2 | 0.62363183 |
| 63 | FGFR1 | 0.62136535 |
| 64 | JAK3 | 0.59567983 |
| 65 | MKNK2 | 0.58090965 |
| 66 | CSNK2A2 | 0.55264115 |
| 67 | PHKG2 | 0.53238289 |
| 68 | PHKG1 | 0.53238289 |
| 69 | AKT3 | 0.52606800 |
| 70 | CAMK2D | 0.52046253 |
| 71 | EGFR | 0.52016687 |
| 72 | LCK | 0.50160806 |
| 73 | CHUK | 0.46156622 |
| 74 | TIE1 | 0.44710995 |
| 75 | FGFR2 | 0.42065454 |
| 76 | BTK | 0.40825114 |
| 77 | CSNK2A1 | 0.40496916 |
| 78 | PLK1 | 0.37613373 |
| 79 | MINK1 | 0.37545427 |
| 80 | KDR | 0.36465252 |
| 81 | HCK | 0.35873713 |
| 82 | ADRBK1 | 0.35769814 |
| 83 | DMPK | 0.34183823 |
| 84 | JAK1 | 0.34103735 |
| 85 | MUSK | 0.33710398 |
| 86 | ERBB3 | 0.33598688 |
| 87 | IGF1R | 0.33416837 |
| 88 | MAP3K7 | 0.33257334 |
| 89 | ATR | 0.32364637 |
| 90 | MKNK1 | 0.31529651 |
| 91 | MAPKAPK3 | 0.31100057 |
| 92 | NME1 | 0.30652073 |
| 93 | EIF2AK2 | 0.30470419 |
| 94 | PLK3 | 0.29731318 |
| 95 | TBK1 | 0.28736668 |
| 96 | SGK1 | 0.27928150 |
| 97 | CAMK2A | 0.27754976 |
| 98 | TAF1 | 0.26677272 |
| 99 | PRKG1 | 0.26284111 |
| 100 | ATM | 0.26224392 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 4.90301549 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 4.67081506 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.46372589 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.30445728 |
| 5 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 4.11621871 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.85912211 |
| 7 | Protein export_Homo sapiens_hsa03060 | 3.54530840 |
| 8 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.88127081 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 2.82220911 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.60057672 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.48988449 |
| 12 | Viral myocarditis_Homo sapiens_hsa05416 | 2.29166924 |
| 13 | Ribosome_Homo sapiens_hsa03010 | 2.29048920 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 2.23450024 |
| 15 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.12334272 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.11345711 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.99028883 |
| 18 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.84211129 |
| 19 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.46025861 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.45316979 |
| 21 | Leishmaniasis_Homo sapiens_hsa05140 | 1.39140992 |
| 22 | Huntingtons disease_Homo sapiens_hsa05016 | 1.37653483 |
| 23 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.30212542 |
| 24 | Mismatch repair_Homo sapiens_hsa03430 | 1.27818522 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.16380004 |
| 26 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.15654818 |
| 27 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.15548908 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.13081378 |
| 29 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.96911702 |
| 30 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.90861463 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.89786027 |
| 32 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.82495488 |
| 33 | RNA transport_Homo sapiens_hsa03013 | 0.80405511 |
| 34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.78348981 |
| 35 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.76548027 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.76021661 |
| 37 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.75352608 |
| 38 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.74231211 |
| 39 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.73644481 |
| 40 | DNA replication_Homo sapiens_hsa03030 | 0.69605195 |
| 41 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.67110239 |
| 42 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.66293720 |
| 43 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59916717 |
| 44 | Phagosome_Homo sapiens_hsa04145 | 0.57660317 |
| 45 | Basal transcription factors_Homo sapiens_hsa03022 | 0.54097481 |
| 46 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51637547 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51280188 |
| 48 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.50514851 |
| 49 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.50423971 |
| 50 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.50164602 |
| 51 | Phototransduction_Homo sapiens_hsa04744 | 0.50006535 |
| 52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.49373383 |
| 53 | Influenza A_Homo sapiens_hsa05164 | 0.47653474 |
| 54 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.46735986 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.45989717 |
| 56 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.45813033 |
| 57 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.44956884 |
| 58 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44951692 |
| 59 | Purine metabolism_Homo sapiens_hsa00230 | 0.44005746 |
| 60 | Tuberculosis_Homo sapiens_hsa05152 | 0.42867915 |
| 61 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.42051611 |
| 62 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.41557726 |
| 63 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.41375833 |
| 64 | Base excision repair_Homo sapiens_hsa03410 | 0.39715281 |
| 65 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.38573721 |
| 66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.34273004 |
| 67 | Measles_Homo sapiens_hsa05162 | 0.33036167 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.32340314 |
| 69 | Spliceosome_Homo sapiens_hsa03040 | 0.31545630 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.31065888 |
| 71 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.30624038 |
| 72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.27428670 |
| 73 | Shigellosis_Homo sapiens_hsa05131 | 0.27329604 |
| 74 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.26193721 |
| 75 | Peroxisome_Homo sapiens_hsa04146 | 0.24947497 |
| 76 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.24347207 |
| 77 | Retinol metabolism_Homo sapiens_hsa00830 | 0.23025807 |
| 78 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.22308173 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.22298279 |
| 80 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.22238624 |
| 81 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.19038483 |
| 82 | Pertussis_Homo sapiens_hsa05133 | 0.18944021 |
| 83 | Salivary secretion_Homo sapiens_hsa04970 | 0.18446145 |
| 84 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.17350990 |
| 85 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.16381404 |
| 86 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.16299824 |
| 87 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.15921123 |
| 88 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.15291096 |
| 89 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.15042756 |
| 90 | Metabolic pathways_Homo sapiens_hsa01100 | 0.14684161 |
| 91 | HTLV-I infection_Homo sapiens_hsa05166 | 0.12518828 |
| 92 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.12030473 |
| 93 | Nicotine addiction_Homo sapiens_hsa05033 | 0.11714405 |
| 94 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.11064892 |
| 95 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.09735663 |
| 96 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.08921316 |
| 97 | Legionellosis_Homo sapiens_hsa05134 | 0.08574709 |
| 98 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.08369043 |
| 99 | Circadian entrainment_Homo sapiens_hsa04713 | 0.07811480 |
| 100 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.06952751 |

