

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.79456898 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.61537934 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.61537934 |
| 4 | DNA deamination (GO:0045006) | 5.51048946 |
| 5 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.06985735 |
| 6 | respiratory electron transport chain (GO:0022904) | 4.56647202 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 4.53374978 |
| 8 | electron transport chain (GO:0022900) | 4.53020062 |
| 9 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.21646568 |
| 10 | cytidine deamination (GO:0009972) | 4.18217023 |
| 11 | cytidine metabolic process (GO:0046087) | 4.18217023 |
| 12 | cytidine catabolic process (GO:0006216) | 4.18217023 |
| 13 | protein neddylation (GO:0045116) | 4.14793887 |
| 14 | protein complex biogenesis (GO:0070271) | 3.98277106 |
| 15 | viral transcription (GO:0019083) | 3.83853563 |
| 16 | translational termination (GO:0006415) | 3.71618790 |
| 17 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.65602669 |
| 18 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.64989706 |
| 19 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.64989706 |
| 20 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.63338573 |
| 21 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.60317126 |
| 22 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.60317126 |
| 23 | NADH dehydrogenase complex assembly (GO:0010257) | 3.60317126 |
| 24 | cotranslational protein targeting to membrane (GO:0006613) | 3.59161677 |
| 25 | protein targeting to ER (GO:0045047) | 3.58359956 |
| 26 | hydrogen ion transmembrane transport (GO:1902600) | 3.53966493 |
| 27 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.53342064 |
| 28 | protein localization to endoplasmic reticulum (GO:0070972) | 3.42993984 |
| 29 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.41921352 |
| 30 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.41909072 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.34727444 |
| 32 | proton transport (GO:0015992) | 3.33958868 |
| 33 | translational elongation (GO:0006414) | 3.32927146 |
| 34 | behavioral response to nicotine (GO:0035095) | 3.30251183 |
| 35 | platelet dense granule organization (GO:0060155) | 3.29839351 |
| 36 | ATP biosynthetic process (GO:0006754) | 3.29608825 |
| 37 | hydrogen transport (GO:0006818) | 3.28281195 |
| 38 | chaperone-mediated protein transport (GO:0072321) | 3.17780198 |
| 39 | respiratory chain complex IV assembly (GO:0008535) | 3.17513122 |
| 40 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.16227779 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.14774604 |
| 42 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.10756484 |
| 43 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.09453609 |
| 44 | sequestering of actin monomers (GO:0042989) | 3.07946016 |
| 45 | cytochrome complex assembly (GO:0017004) | 3.07846590 |
| 46 | negative regulation of mast cell activation (GO:0033004) | 3.03632284 |
| 47 | proteasome assembly (GO:0043248) | 3.00183969 |
| 48 | indole-containing compound catabolic process (GO:0042436) | 2.97315943 |
| 49 | indolalkylamine catabolic process (GO:0046218) | 2.97315943 |
| 50 | tryptophan catabolic process (GO:0006569) | 2.97315943 |
| 51 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.93139932 |
| 52 | kynurenine metabolic process (GO:0070189) | 2.91935710 |
| 53 | termination of RNA polymerase III transcription (GO:0006386) | 2.91392513 |
| 54 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.91392513 |
| 55 | GPI anchor metabolic process (GO:0006505) | 2.85172237 |
| 56 | maturation of SSU-rRNA (GO:0030490) | 2.84946324 |
| 57 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.84145490 |
| 58 | regulation of regulatory T cell differentiation (GO:0045589) | 2.83179937 |
| 59 | translation (GO:0006412) | 2.80199122 |
| 60 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.78634435 |
| 61 | GPI anchor biosynthetic process (GO:0006506) | 2.76815251 |
| 62 | ribosomal large subunit biogenesis (GO:0042273) | 2.76304030 |
| 63 | mannosylation (GO:0097502) | 2.76251086 |
| 64 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.72125649 |
| 65 | response to pheromone (GO:0019236) | 2.70273140 |
| 66 | cellular response to interleukin-15 (GO:0071350) | 2.70188778 |
| 67 | indolalkylamine metabolic process (GO:0006586) | 2.69172293 |
| 68 | viral life cycle (GO:0019058) | 2.69118170 |
| 69 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.68780431 |
| 70 | cellular protein complex disassembly (GO:0043624) | 2.68717185 |
| 71 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.65718203 |
| 72 | regulation of chronic inflammatory response (GO:0002676) | 2.64391572 |
| 73 | protein-cofactor linkage (GO:0018065) | 2.63594474 |
| 74 | mast cell activation (GO:0045576) | 2.62527724 |
| 75 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.59626680 |
| 76 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.59626680 |
| 77 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.59626680 |
| 78 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.59428259 |
| 79 | peptidyl-histidine modification (GO:0018202) | 2.57930962 |
| 80 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.56134912 |
| 81 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.56134912 |
| 82 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.55982981 |
| 83 | interferon-gamma production (GO:0032609) | 2.55405043 |
| 84 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.55134687 |
| 85 | translational initiation (GO:0006413) | 2.54728442 |
| 86 | negative T cell selection (GO:0043383) | 2.54144610 |
| 87 | tryptophan metabolic process (GO:0006568) | 2.52816750 |
| 88 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.52811432 |
| 89 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.52697807 |
| 90 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.51747510 |
| 91 | GTP biosynthetic process (GO:0006183) | 2.51057407 |
| 92 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.51053116 |
| 93 | cellular ketone body metabolic process (GO:0046950) | 2.50751394 |
| 94 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.49373262 |
| 95 | regulation of interleukin-8 secretion (GO:2000482) | 2.48176496 |
| 96 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.47295514 |
| 97 | S-adenosylmethionine metabolic process (GO:0046500) | 2.47215822 |
| 98 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.45553794 |
| 99 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.43675395 |
| 100 | sulfation (GO:0051923) | 2.43482564 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.39073402 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.25499878 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.02603198 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.99242828 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.86016202 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.79039859 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.59643873 |
| 8 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.55132914 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.47543490 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.46277720 |
| 11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.37319850 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.27072694 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.25937508 |
| 14 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.18019747 |
| 15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.16563096 |
| 16 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.15236289 |
| 17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.05030770 |
| 18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.01469509 |
| 19 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.99195737 |
| 20 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.97350073 |
| 21 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.89917279 |
| 22 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.89343827 |
| 23 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.84088434 |
| 24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.82987425 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.82178402 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.78165835 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.71001347 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.65555467 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.64848733 |
| 30 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.60589684 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.57459619 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.53544429 |
| 33 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.51949070 |
| 34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.51882640 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50129737 |
| 36 | GATA3_26560356_Chip-Seq_TH2_Human | 1.48946227 |
| 37 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.48923010 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.48711430 |
| 39 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.48711430 |
| 40 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.48264484 |
| 41 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.44318490 |
| 42 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.43132504 |
| 43 | AR_20517297_ChIP-Seq_VCAP_Human | 1.42358597 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.42107413 |
| 45 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.38723875 |
| 46 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.37862178 |
| 47 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.34099989 |
| 48 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.33265817 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.32745712 |
| 50 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.32534559 |
| 51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.32104354 |
| 52 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.29916000 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.28574368 |
| 54 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.27222701 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.25650938 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.25650938 |
| 57 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.24591390 |
| 58 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.24586227 |
| 59 | MYB_26560356_Chip-Seq_TH2_Human | 1.22334582 |
| 60 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.21270674 |
| 61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.20315345 |
| 62 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.18316957 |
| 63 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18134076 |
| 64 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.17058311 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.16965571 |
| 66 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.16943957 |
| 67 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.16796578 |
| 68 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.16796578 |
| 69 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.15925128 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.15782532 |
| 71 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15681218 |
| 72 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.14035803 |
| 73 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.13987392 |
| 74 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.13443033 |
| 75 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13247937 |
| 76 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.11868801 |
| 77 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.09882352 |
| 78 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.09544530 |
| 79 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.09118792 |
| 80 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.08271882 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.07668140 |
| 82 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.05501320 |
| 83 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.04634086 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.03814625 |
| 85 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.02235082 |
| 86 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.01428289 |
| 87 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00988910 |
| 88 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.99952875 |
| 89 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.99080804 |
| 90 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.99078663 |
| 91 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.99041201 |
| 92 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.98811507 |
| 93 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.98179414 |
| 94 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.98161906 |
| 95 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.95941910 |
| 96 | ERA_21632823_ChIP-Seq_H3396_Human | 0.94373631 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.94090947 |
| 98 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.93979596 |
| 99 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.93521340 |
| 100 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.93081260 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.15598493 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.16398038 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.14545134 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.44558924 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 2.37845353 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.14609081 |
| 7 | MP0002102_abnormal_ear_morphology | 2.14550280 |
| 8 | MP0008875_abnormal_xenobiotic_pharmacok | 2.09691455 |
| 9 | MP0009785_altered_susceptibility_to | 2.08047990 |
| 10 | MP0008872_abnormal_physiological_respon | 2.01988070 |
| 11 | MP0002163_abnormal_gland_morphology | 2.00782231 |
| 12 | MP0002876_abnormal_thyroid_physiology | 1.99097039 |
| 13 | MP0006292_abnormal_olfactory_placode | 1.97302981 |
| 14 | MP0005645_abnormal_hypothalamus_physiol | 1.97229758 |
| 15 | MP0003195_calcinosis | 1.94704485 |
| 16 | MP0005551_abnormal_eye_electrophysiolog | 1.87385877 |
| 17 | MP0005646_abnormal_pituitary_gland | 1.79538692 |
| 18 | MP0004142_abnormal_muscle_tone | 1.75062352 |
| 19 | MP0000372_irregular_coat_pigmentation | 1.73976095 |
| 20 | MP0001800_abnormal_humoral_immune | 1.68737067 |
| 21 | MP0003011_delayed_dark_adaptation | 1.68359297 |
| 22 | MP0003646_muscle_fatigue | 1.66844893 |
| 23 | MP0003806_abnormal_nucleotide_metabolis | 1.65707422 |
| 24 | MP0005000_abnormal_immune_tolerance | 1.65456681 |
| 25 | MP0001986_abnormal_taste_sensitivity | 1.63081076 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.62837574 |
| 27 | MP0005075_abnormal_melanosome_morpholog | 1.62813886 |
| 28 | MP0002166_altered_tumor_susceptibility | 1.60299178 |
| 29 | MP0005253_abnormal_eye_physiology | 1.56766857 |
| 30 | MP0002148_abnormal_hypersensitivity_rea | 1.54606425 |
| 31 | MP0004885_abnormal_endolymph | 1.53522024 |
| 32 | MP0000685_abnormal_immune_system | 1.52932297 |
| 33 | MP0001905_abnormal_dopamine_level | 1.50953712 |
| 34 | MP0001919_abnormal_reproductive_system | 1.48887763 |
| 35 | MP0005379_endocrine/exocrine_gland_phen | 1.45562153 |
| 36 | MP0001873_stomach_inflammation | 1.45116040 |
| 37 | MP0005387_immune_system_phenotype | 1.41485253 |
| 38 | MP0001790_abnormal_immune_system | 1.41485253 |
| 39 | MP0002006_tumorigenesis | 1.41343229 |
| 40 | MP0002723_abnormal_immune_serum | 1.41049514 |
| 41 | MP0009333_abnormal_splenocyte_physiolog | 1.40475447 |
| 42 | MP0002736_abnormal_nociception_after | 1.39695175 |
| 43 | MP0003878_abnormal_ear_physiology | 1.38306879 |
| 44 | MP0005377_hearing/vestibular/ear_phenot | 1.38306879 |
| 45 | MP0004145_abnormal_muscle_electrophysio | 1.35884442 |
| 46 | MP0003866_abnormal_defecation | 1.34228512 |
| 47 | MP0003763_abnormal_thymus_physiology | 1.32395821 |
| 48 | MP0002420_abnormal_adaptive_immunity | 1.30091605 |
| 49 | MP0005389_reproductive_system_phenotype | 1.29759795 |
| 50 | MP0001819_abnormal_immune_cell | 1.29492373 |
| 51 | MP0002452_abnormal_antigen_presenting | 1.27433071 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.26844512 |
| 53 | MP0004147_increased_porphyrin_level | 1.26074546 |
| 54 | MP0003787_abnormal_imprinting | 1.25356353 |
| 55 | MP0003724_increased_susceptibility_to | 1.24998935 |
| 56 | MP0006082_CNS_inflammation | 1.23847153 |
| 57 | MP0003880_abnormal_central_pattern | 1.22190280 |
| 58 | MP0005084_abnormal_gallbladder_morpholo | 1.21902801 |
| 59 | MP0009764_decreased_sensitivity_to | 1.21614426 |
| 60 | MP0002638_abnormal_pupillary_reflex | 1.21373329 |
| 61 | MP0002138_abnormal_hepatobiliary_system | 1.19089366 |
| 62 | MP0005025_abnormal_response_to | 1.17802200 |
| 63 | MP0006276_abnormal_autonomic_nervous | 1.16595937 |
| 64 | MP0009745_abnormal_behavioral_response | 1.13768231 |
| 65 | MP0002272_abnormal_nervous_system | 1.11351839 |
| 66 | MP0001984_abnormal_olfaction | 1.06086648 |
| 67 | MP0006036_abnormal_mitochondrial_physio | 1.05951786 |
| 68 | MP0008995_early_reproductive_senescence | 1.05716033 |
| 69 | MP0001485_abnormal_pinna_reflex | 0.99963099 |
| 70 | MP0010386_abnormal_urinary_bladder | 0.98828260 |
| 71 | MP0005410_abnormal_fertilization | 0.95943284 |
| 72 | MP0001970_abnormal_pain_threshold | 0.94167025 |
| 73 | MP0002693_abnormal_pancreas_physiology | 0.92294438 |
| 74 | MP0002938_white_spotting | 0.92251757 |
| 75 | MP0005636_abnormal_mineral_homeostasis | 0.92093049 |
| 76 | MP0001529_abnormal_vocalization | 0.91720315 |
| 77 | MP0002095_abnormal_skin_pigmentation | 0.91182084 |
| 78 | MP0010155_abnormal_intestine_physiology | 0.91137399 |
| 79 | MP0001845_abnormal_inflammatory_respons | 0.90542283 |
| 80 | MP0001501_abnormal_sleep_pattern | 0.89471794 |
| 81 | MP0001765_abnormal_ion_homeostasis | 0.89304350 |
| 82 | MP0000716_abnormal_immune_system | 0.89293255 |
| 83 | MP0000631_abnormal_neuroendocrine_gland | 0.89112312 |
| 84 | MP0004043_abnormal_pH_regulation | 0.83086827 |
| 85 | MP0003252_abnormal_bile_duct | 0.82898802 |
| 86 | MP0003283_abnormal_digestive_organ | 0.82823667 |
| 87 | MP0001764_abnormal_homeostasis | 0.82722870 |
| 88 | MP0009046_muscle_twitch | 0.82416421 |
| 89 | MP0005085_abnormal_gallbladder_physiolo | 0.82216504 |
| 90 | MP0005332_abnormal_amino_acid | 0.81345914 |
| 91 | MP0001486_abnormal_startle_reflex | 0.79436895 |
| 92 | MP0002933_joint_inflammation | 0.79436704 |
| 93 | MP0002234_abnormal_pharynx_morphology | 0.78560701 |
| 94 | MP0004742_abnormal_vestibular_system | 0.76371222 |
| 95 | MP0003786_premature_aging | 0.76263199 |
| 96 | MP0002160_abnormal_reproductive_system | 0.74987562 |
| 97 | MP0003638_abnormal_response/metabolism_ | 0.74413678 |
| 98 | MP0002398_abnormal_bone_marrow | 0.72314792 |
| 99 | MP0003436_decreased_susceptibility_to | 0.72091252 |
| 100 | MP0003186_abnormal_redox_activity | 0.70776468 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.84382063 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.54692902 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.29148091 |
| 4 | Progressive macrocephaly (HP:0004481) | 4.15669804 |
| 5 | Acute encephalopathy (HP:0006846) | 4.11306277 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.97125912 |
| 7 | Increased CSF lactate (HP:0002490) | 3.91341520 |
| 8 | 3-Methylglutaconic aciduria (HP:0003535) | 3.86302514 |
| 9 | IgG deficiency (HP:0004315) | 3.69844201 |
| 10 | Congenital stationary night blindness (HP:0007642) | 3.65631954 |
| 11 | Hepatic necrosis (HP:0002605) | 3.48990601 |
| 12 | Pancreatic cysts (HP:0001737) | 3.47520189 |
| 13 | Congenital, generalized hypertrichosis (HP:0004540) | 3.29315226 |
| 14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.29203822 |
| 15 | Aplastic anemia (HP:0001915) | 3.27941398 |
| 16 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.17524112 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.15207143 |
| 18 | Cerebral edema (HP:0002181) | 3.09379529 |
| 19 | Stomatitis (HP:0010280) | 2.96384400 |
| 20 | Abnormality of midbrain morphology (HP:0002418) | 2.95867724 |
| 21 | Molar tooth sign on MRI (HP:0002419) | 2.95867724 |
| 22 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.94243229 |
| 23 | Optic disc pallor (HP:0000543) | 2.90379808 |
| 24 | Pancreatic fibrosis (HP:0100732) | 2.87369891 |
| 25 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.87318472 |
| 26 | True hermaphroditism (HP:0010459) | 2.79016929 |
| 27 | Abolished electroretinogram (ERG) (HP:0000550) | 2.78680483 |
| 28 | Methylmalonic acidemia (HP:0002912) | 2.75306874 |
| 29 | Increased intramyocellular lipid droplets (HP:0012240) | 2.73893060 |
| 30 | Hypoproteinemia (HP:0003075) | 2.73517378 |
| 31 | Renal Fanconi syndrome (HP:0001994) | 2.72743535 |
| 32 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.72150661 |
| 33 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.72150661 |
| 34 | Attenuation of retinal blood vessels (HP:0007843) | 2.65830726 |
| 35 | Severe combined immunodeficiency (HP:0004430) | 2.48025044 |
| 36 | Lactic acidosis (HP:0003128) | 2.45624687 |
| 37 | Increased serum lactate (HP:0002151) | 2.44685585 |
| 38 | Exertional dyspnea (HP:0002875) | 2.44174173 |
| 39 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.40570268 |
| 40 | Increased muscle lipid content (HP:0009058) | 2.33400449 |
| 41 | Respiratory failure (HP:0002878) | 2.32895754 |
| 42 | Decreased central vision (HP:0007663) | 2.28294549 |
| 43 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.28160412 |
| 44 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.27666145 |
| 45 | T lymphocytopenia (HP:0005403) | 2.27564045 |
| 46 | Thyroiditis (HP:0100646) | 2.27477882 |
| 47 | Methylmalonic aciduria (HP:0012120) | 2.27459848 |
| 48 | Abnormality of T cell number (HP:0011839) | 2.25447479 |
| 49 | Nephronophthisis (HP:0000090) | 2.22325518 |
| 50 | Abnormal number of erythroid precursors (HP:0012131) | 2.19088838 |
| 51 | Abnormality of the prostate (HP:0008775) | 2.17313583 |
| 52 | Lethargy (HP:0001254) | 2.17306523 |
| 53 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.15692588 |
| 54 | Hypothermia (HP:0002045) | 2.13525026 |
| 55 | Abnormality of the renal cortex (HP:0011035) | 2.12392065 |
| 56 | Macrocytic anemia (HP:0001972) | 2.11649607 |
| 57 | Abnormality of T cells (HP:0002843) | 2.10929914 |
| 58 | Leukodystrophy (HP:0002415) | 2.08940717 |
| 59 | Increased IgM level (HP:0003496) | 2.04349059 |
| 60 | Pendular nystagmus (HP:0012043) | 2.01471542 |
| 61 | Sclerocornea (HP:0000647) | 2.01394336 |
| 62 | Abnormality of B cell number (HP:0010975) | 2.00481159 |
| 63 | Constricted visual fields (HP:0001133) | 1.97298767 |
| 64 | Renal cortical cysts (HP:0000803) | 1.95247573 |
| 65 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.92901361 |
| 66 | Reticulocytopenia (HP:0001896) | 1.91842451 |
| 67 | Abnormal albumin level (HP:0012116) | 1.91829966 |
| 68 | Hypoalbuminemia (HP:0003073) | 1.91829966 |
| 69 | Exercise intolerance (HP:0003546) | 1.89702779 |
| 70 | Medial flaring of the eyebrow (HP:0010747) | 1.89009193 |
| 71 | Chronic diarrhea (HP:0002028) | 1.87402453 |
| 72 | Pancytopenia (HP:0001876) | 1.84881291 |
| 73 | Male pseudohermaphroditism (HP:0000037) | 1.84823739 |
| 74 | Cystic liver disease (HP:0006706) | 1.82514302 |
| 75 | Abnormal drinking behavior (HP:0030082) | 1.82223176 |
| 76 | Polydipsia (HP:0001959) | 1.82223176 |
| 77 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.80982220 |
| 78 | Abnormality of renal resorption (HP:0011038) | 1.80779112 |
| 79 | Hyperglycinemia (HP:0002154) | 1.80450837 |
| 80 | Abnormality of the renal medulla (HP:0100957) | 1.80226008 |
| 81 | B lymphocytopenia (HP:0010976) | 1.79895687 |
| 82 | Abnormality of urine glucose concentration (HP:0011016) | 1.78375572 |
| 83 | Glycosuria (HP:0003076) | 1.78375572 |
| 84 | Ketosis (HP:0001946) | 1.78319919 |
| 85 | Abnormality of eosinophils (HP:0001879) | 1.78253468 |
| 86 | Hypomagnesemia (HP:0002917) | 1.76701403 |
| 87 | Combined immunodeficiency (HP:0005387) | 1.76279293 |
| 88 | Increased corneal curvature (HP:0100692) | 1.75163565 |
| 89 | Keratoconus (HP:0000563) | 1.75163565 |
| 90 | Abnormality of vitamin B metabolism (HP:0004340) | 1.73879836 |
| 91 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.72757224 |
| 92 | Abnormality of alanine metabolism (HP:0010916) | 1.72757224 |
| 93 | Hyperalaninemia (HP:0003348) | 1.72757224 |
| 94 | Absent thumb (HP:0009777) | 1.72552399 |
| 95 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.72342438 |
| 96 | Type II lissencephaly (HP:0007260) | 1.71054854 |
| 97 | Cerebral palsy (HP:0100021) | 1.68917018 |
| 98 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.68719272 |
| 99 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.68304990 |
| 100 | Asplenia (HP:0001746) | 1.68034771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.34487511 |
| 2 | MAP4K2 | 3.10948166 |
| 3 | FRK | 3.07427318 |
| 4 | KDR | 2.99146316 |
| 5 | GRK1 | 2.57336024 |
| 6 | ADRBK2 | 2.56443110 |
| 7 | ZAK | 2.53554674 |
| 8 | TLK1 | 2.46889733 |
| 9 | CDK19 | 2.44031545 |
| 10 | MAP3K12 | 2.29875317 |
| 11 | TAOK3 | 2.20230137 |
| 12 | BCKDK | 2.11751125 |
| 13 | NUAK1 | 2.05406508 |
| 14 | TESK2 | 2.05179209 |
| 15 | MAP4K1 | 1.95293918 |
| 16 | VRK2 | 1.88554844 |
| 17 | WNK3 | 1.85393177 |
| 18 | WNK4 | 1.79270901 |
| 19 | PINK1 | 1.77518336 |
| 20 | BMPR2 | 1.69466605 |
| 21 | ITK | 1.61216938 |
| 22 | STK16 | 1.57471695 |
| 23 | TEC | 1.51701105 |
| 24 | NME1 | 1.37219549 |
| 25 | MYLK | 1.33848643 |
| 26 | MST4 | 1.31421441 |
| 27 | TIE1 | 1.27294193 |
| 28 | GRK6 | 1.25204314 |
| 29 | VRK1 | 1.21772128 |
| 30 | PASK | 1.21546968 |
| 31 | IKBKB | 1.20307542 |
| 32 | INSRR | 1.17319197 |
| 33 | MUSK | 1.14842441 |
| 34 | SCYL2 | 1.11882990 |
| 35 | OXSR1 | 1.11853820 |
| 36 | LIMK1 | 1.11633517 |
| 37 | FES | 1.09459176 |
| 38 | ERBB3 | 1.09370068 |
| 39 | SYK | 1.03612563 |
| 40 | DYRK2 | 1.00895827 |
| 41 | CSF1R | 0.93582687 |
| 42 | BTK | 0.87802184 |
| 43 | LYN | 0.87458258 |
| 44 | KIT | 0.87335005 |
| 45 | PHKG2 | 0.83859830 |
| 46 | PHKG1 | 0.83859830 |
| 47 | LCK | 0.83758939 |
| 48 | CAMKK2 | 0.81757272 |
| 49 | GRK7 | 0.76280602 |
| 50 | PRKCQ | 0.75540266 |
| 51 | BMPR1B | 0.74252435 |
| 52 | TRIM28 | 0.73946015 |
| 53 | CSNK1G3 | 0.73347556 |
| 54 | RPS6KA5 | 0.72624687 |
| 55 | ADRBK1 | 0.72000324 |
| 56 | PIK3CA | 0.69808685 |
| 57 | DAPK1 | 0.68661110 |
| 58 | TNK2 | 0.67944846 |
| 59 | OBSCN | 0.65524499 |
| 60 | IKBKE | 0.65120524 |
| 61 | TRPM7 | 0.62092737 |
| 62 | DAPK2 | 0.61846471 |
| 63 | STK39 | 0.60781507 |
| 64 | CSNK1G2 | 0.60667740 |
| 65 | ILK | 0.60575630 |
| 66 | EIF2AK3 | 0.59236699 |
| 67 | MAPK13 | 0.57388284 |
| 68 | IGF1R | 0.57036808 |
| 69 | CSNK1G1 | 0.54895761 |
| 70 | PRKCE | 0.50993020 |
| 71 | DAPK3 | 0.50326074 |
| 72 | PRKACA | 0.49662649 |
| 73 | MATK | 0.49366481 |
| 74 | MAP3K4 | 0.49123204 |
| 75 | PIM1 | 0.48383721 |
| 76 | MAP2K6 | 0.47717432 |
| 77 | CDK8 | 0.46578477 |
| 78 | ACVR1B | 0.46321416 |
| 79 | PLK4 | 0.45456223 |
| 80 | PRKCA | 0.45429591 |
| 81 | FLT3 | 0.44957634 |
| 82 | BUB1 | 0.44529140 |
| 83 | PAK3 | 0.43726346 |
| 84 | MAP2K7 | 0.42119626 |
| 85 | PRKCG | 0.39482230 |
| 86 | CSK | 0.38960150 |
| 87 | CAMK2A | 0.38527703 |
| 88 | MAP3K11 | 0.38232643 |
| 89 | CSNK1A1 | 0.38131986 |
| 90 | CSNK1A1L | 0.37781766 |
| 91 | MAPKAPK3 | 0.37745440 |
| 92 | CSNK2A1 | 0.37551371 |
| 93 | PIK3CG | 0.37245948 |
| 94 | CSNK2A2 | 0.36383837 |
| 95 | SRPK1 | 0.34558205 |
| 96 | NEK1 | 0.33786440 |
| 97 | CAMKK1 | 0.33595993 |
| 98 | ROCK1 | 0.33162252 |
| 99 | EIF2AK2 | 0.32236697 |
| 100 | ERBB2 | 0.32077423 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.18963245 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.48942606 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.46771066 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.29412005 |
| 5 | Asthma_Homo sapiens_hsa05310 | 3.02430268 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.85417746 |
| 7 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.84066143 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.79271900 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.65102906 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.62652361 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.49803529 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.45398362 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.25712641 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.08432391 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 2.07596553 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.99085685 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.95685659 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.82232335 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.80271060 |
| 20 | Phototransduction_Homo sapiens_hsa04744 | 1.76149784 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.53797741 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.53038407 |
| 23 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.46710670 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.43395862 |
| 25 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.41655037 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.40336022 |
| 27 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.27041769 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.25287283 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.24602898 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.21214732 |
| 31 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.13520378 |
| 32 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.10331731 |
| 33 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.08334200 |
| 34 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.02053520 |
| 35 | Basal transcription factors_Homo sapiens_hsa03022 | 1.01862043 |
| 36 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.96690202 |
| 37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.92072439 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.91701120 |
| 39 | Viral myocarditis_Homo sapiens_hsa05416 | 0.87334841 |
| 40 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87105150 |
| 41 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.86305173 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.86061635 |
| 43 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.84943829 |
| 44 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.83207503 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.82138973 |
| 46 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.81056233 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80306029 |
| 48 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.77851813 |
| 49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.77343342 |
| 50 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.76400441 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.75468377 |
| 52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.74504408 |
| 53 | Nicotine addiction_Homo sapiens_hsa05033 | 0.73881124 |
| 54 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.72633645 |
| 55 | Olfactory transduction_Homo sapiens_hsa04740 | 0.71708030 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.71456338 |
| 57 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.70137236 |
| 58 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69958227 |
| 59 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.68837805 |
| 60 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68555357 |
| 61 | Mismatch repair_Homo sapiens_hsa03430 | 0.68517691 |
| 62 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.67258637 |
| 63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.65001813 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64958161 |
| 65 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.64098204 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63736700 |
| 67 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.59963201 |
| 68 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.55940790 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.55562842 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54815220 |
| 71 | Spliceosome_Homo sapiens_hsa03040 | 0.53234568 |
| 72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.51995735 |
| 73 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50508256 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.48518695 |
| 75 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.46329935 |
| 76 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.45646483 |
| 77 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.44077889 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.43648037 |
| 79 | Morphine addiction_Homo sapiens_hsa05032 | 0.40545764 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.40130050 |
| 81 | RNA transport_Homo sapiens_hsa03013 | 0.38512964 |
| 82 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.37632240 |
| 83 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37115157 |
| 84 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.36170498 |
| 85 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.35736332 |
| 86 | DNA replication_Homo sapiens_hsa03030 | 0.35588316 |
| 87 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32576238 |
| 88 | Salivary secretion_Homo sapiens_hsa04970 | 0.32232848 |
| 89 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.27247683 |
| 90 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.25411096 |
| 91 | Leishmaniasis_Homo sapiens_hsa05140 | 0.25295904 |
| 92 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.24724432 |
| 93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.24165200 |
| 94 | Base excision repair_Homo sapiens_hsa03410 | 0.23223074 |
| 95 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.23222113 |
| 96 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.22839214 |
| 97 | GABAergic synapse_Homo sapiens_hsa04727 | 0.22226244 |
| 98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.21719559 |
| 99 | Measles_Homo sapiens_hsa05162 | 0.19537215 |
| 100 | ABC transporters_Homo sapiens_hsa02010 | 0.19332873 |

