RPL22L1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)9.06354572
2viral transcription (GO:0019083)8.98010896
3translational termination (GO:0006415)8.68743168
4ribosomal small subunit biogenesis (GO:0042274)8.30073021
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)7.91119242
6cotranslational protein targeting to membrane (GO:0006613)7.83770534
7protein targeting to ER (GO:0045047)7.77850772
8establishment of protein localization to endoplasmic reticulum (GO:0072599)7.42248131
9translational elongation (GO:0006414)7.40304049
10protein localization to endoplasmic reticulum (GO:0070972)7.36469217
11maturation of SSU-rRNA (GO:0030490)6.81886937
12viral life cycle (GO:0019058)6.80426853
13cellular protein complex disassembly (GO:0043624)6.77034747
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)6.65552620
15translational initiation (GO:0006413)6.35471826
16ribosomal large subunit biogenesis (GO:0042273)5.90630977
17protein complex disassembly (GO:0043241)5.81285433
18mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.53467066
19macromolecular complex disassembly (GO:0032984)5.49910266
20ATP synthesis coupled proton transport (GO:0015986)5.24648421
21energy coupled proton transport, down electrochemical gradient (GO:0015985)5.24648421
22* translation (GO:0006412)5.20049618
23protein targeting to membrane (GO:0006612)5.17568060
24nuclear-transcribed mRNA catabolic process (GO:0000956)4.90664691
25mRNA catabolic process (GO:0006402)4.64583748
26ribonucleoprotein complex biogenesis (GO:0022613)4.59991110
27establishment of protein localization to mitochondrial membrane (GO:0090151)4.41599689
28DNA deamination (GO:0045006)4.39267765
29RNA catabolic process (GO:0006401)4.28311613
30rRNA modification (GO:0000154)4.28238641
31establishment of integrated proviral latency (GO:0075713)4.11069358
32formation of translation preinitiation complex (GO:0001731)4.06998872
33mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.01697375
34rRNA methylation (GO:0031167)3.94336995
35ribosome assembly (GO:0042255)3.91219958
36cellular component biogenesis (GO:0044085)3.88923418
37DNA replication checkpoint (GO:0000076)3.84328219
38rRNA processing (GO:0006364)3.83402016
39ribosome biogenesis (GO:0042254)3.82718553
40respiratory electron transport chain (GO:0022904)3.75885620
41proteasome assembly (GO:0043248)3.74555118
42GTP biosynthetic process (GO:0006183)3.70677731
43mitotic metaphase plate congression (GO:0007080)3.70105732
44electron transport chain (GO:0022900)3.68744745
45rRNA metabolic process (GO:0016072)3.67871563
46establishment of protein localization to membrane (GO:0090150)3.65042734
47pseudouridine synthesis (GO:0001522)3.58015882
48negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.56818779
49transcription elongation from RNA polymerase I promoter (GO:0006362)3.49964868
50histone exchange (GO:0043486)3.49659877
51protein targeting (GO:0006605)3.48935287
52telomere maintenance via semi-conservative replication (GO:0032201)3.47950194
53folic acid-containing compound biosynthetic process (GO:0009396)3.46260173
54UTP biosynthetic process (GO:0006228)3.45623373
55termination of RNA polymerase III transcription (GO:0006386)3.45538020
56transcription elongation from RNA polymerase III promoter (GO:0006385)3.45538020
57regulation of translational fidelity (GO:0006450)3.43374248
58establishment of viral latency (GO:0019043)3.40826639
59establishment of protein localization to organelle (GO:0072594)3.35473488
60exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.34739216
61DNA replication-independent nucleosome organization (GO:0034724)3.34556266
62DNA replication-independent nucleosome assembly (GO:0006336)3.34556266
63nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.32977373
64DNA strand elongation involved in DNA replication (GO:0006271)3.30094810
65deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.29453941
66antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.27787914
67negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.25885101
68negative regulation of ligase activity (GO:0051352)3.25885101
69positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.23664160
70transcription from mitochondrial promoter (GO:0006390)3.23220652
71DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.22372313
72purine nucleobase biosynthetic process (GO:0009113)3.21989802
73guanosine-containing compound biosynthetic process (GO:1901070)3.19983239
74spliceosomal snRNP assembly (GO:0000387)3.19979600
75nucleobase biosynthetic process (GO:0046112)3.19942011
76regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.17798075
77regulation of cellular amino acid metabolic process (GO:0006521)3.17755206
78protein complex biogenesis (GO:0070271)3.17086256
79intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.16546731
80signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.16546731
81IMP biosynthetic process (GO:0006188)3.16544015
82DNA replication-dependent nucleosome organization (GO:0034723)3.16457627
83DNA replication-dependent nucleosome assembly (GO:0006335)3.16457627
84protein localization to kinetochore (GO:0034501)3.15822168
85DNA strand elongation (GO:0022616)3.15728517
86maturation of 5.8S rRNA (GO:0000460)3.15234525
87transcription from RNA polymerase I promoter (GO:0006360)3.13481777
88signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.11247219
89signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.11247219
90signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.11247219
91mitochondrial respiratory chain complex assembly (GO:0033108)3.07539348
92mitochondrial respiratory chain complex I assembly (GO:0032981)3.07440457
93NADH dehydrogenase complex assembly (GO:0010257)3.07440457
94mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.07440457
95regulation of mitochondrial translation (GO:0070129)3.07396368
96CTP metabolic process (GO:0046036)3.07099638
97CTP biosynthetic process (GO:0006241)3.07099638
98spliceosomal complex assembly (GO:0000245)3.07051801
99DNA-templated transcription, termination (GO:0006353)3.06571464
100chaperone-mediated protein transport (GO:0072321)3.05114627
101anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.04752728
102metaphase plate congression (GO:0051310)3.04628271
103antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.04419722
104ncRNA processing (GO:0034470)3.04016557
1057-methylguanosine mRNA capping (GO:0006370)3.03546940
106telomere maintenance via recombination (GO:0000722)3.03368684
107UTP metabolic process (GO:0046051)3.03324046
108signal transduction involved in DNA integrity checkpoint (GO:0072401)3.02410684
109signal transduction involved in DNA damage checkpoint (GO:0072422)3.02410684
110respiratory chain complex IV assembly (GO:0008535)3.02272390
111protein localization to mitochondrion (GO:0070585)3.01893029
112RNA capping (GO:0036260)3.00504336
1137-methylguanosine RNA capping (GO:0009452)3.00504336
114transcription-coupled nucleotide-excision repair (GO:0006283)2.99965660
115DNA replication initiation (GO:0006270)2.99302088
116pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.99070206
117RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.98239758
118tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.98239758
119protein localization to chromosome, centromeric region (GO:0071459)2.98141961
120ncRNA metabolic process (GO:0034660)2.98035812
121establishment of protein localization to mitochondrion (GO:0072655)2.97939943
122CENP-A containing nucleosome assembly (GO:0034080)2.97927584
123nucleobase-containing small molecule interconversion (GO:0015949)2.97101114
124signal transduction involved in cell cycle checkpoint (GO:0072395)2.96758229
125pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.96621849
126kinetochore organization (GO:0051383)2.96012249
127pteridine-containing compound biosynthetic process (GO:0042559)2.95816192
128protein targeting to mitochondrion (GO:0006626)2.95192209
129pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.92964982
130amino acid activation (GO:0043038)2.92603603
131tRNA aminoacylation (GO:0043039)2.92603603
132mitotic recombination (GO:0006312)2.90810781
133chromatin remodeling at centromere (GO:0031055)2.89874472
134pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.88593376
135oxidative phosphorylation (GO:0006119)2.88215053
136regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.87804103
137termination of RNA polymerase I transcription (GO:0006363)2.87504716

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse5.12202461
2E2F7_22180533_ChIP-Seq_HELA_Human5.01108658
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.38408676
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.30388385
5KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.26245103
6EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.19052682
7EST1_17652178_ChIP-ChIP_JURKAT_Human4.16853450
8HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.62200464
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.57952723
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.39828953
11MYC_19079543_ChIP-ChIP_MESCs_Mouse3.39328628
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.13899978
13CREB1_15753290_ChIP-ChIP_HEK293T_Human3.13307234
14CHD1_19587682_ChIP-ChIP_MESCs_Mouse3.04918911
15* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.99958496
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.99503171
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.98432716
18* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.82732257
19* VDR_23849224_ChIP-Seq_CD4+_Human2.82289848
20* XRN2_22483619_ChIP-Seq_HELA_Human2.78209713
21E2F4_17652178_ChIP-ChIP_JURKAT_Human2.76520320
22CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.69955595
23ELK1_19687146_ChIP-ChIP_HELA_Human2.68055985
24* TTF2_22483619_ChIP-Seq_HELA_Human2.49945368
25DCP1A_22483619_ChIP-Seq_HELA_Human2.45329259
26FOXP3_21729870_ChIP-Seq_TREG_Human2.38961581
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.30563879
28* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.22576309
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18794291
30FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.16603946
31TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.12226669
32FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.02323420
33THAP11_20581084_ChIP-Seq_MESCs_Mouse1.97448071
34FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.97113161
35GABP_19822575_ChIP-Seq_HepG2_Human1.93094895
36ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.92927611
37* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.92659221
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.91420227
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.80084316
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.77519629
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.75409642
42ELK1_22589737_ChIP-Seq_MCF10A_Human1.74644706
43ERG_20887958_ChIP-Seq_HPC-7_Mouse1.72895645
44YY1_21170310_ChIP-Seq_MESCs_Mouse1.72169255
45MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.72071720
46PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.65876798
47CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.65667700
48KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.60945576
49* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56051888
50HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.52557966
51POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.51382411
52* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.48101556
53MYC_18940864_ChIP-ChIP_HL60_Human1.47799171
54NOTCH1_21737748_ChIP-Seq_TLL_Human1.45142065
55MYCN_18555785_ChIP-Seq_MESCs_Mouse1.43867524
56RBPJ_22232070_ChIP-Seq_NCS_Mouse1.41413667
57* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.38218124
58MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.34255843
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.33702259
60CIITA_25753668_ChIP-Seq_RAJI_Human1.30984029
61CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.29664009
62FOXM1_23109430_ChIP-Seq_U2OS_Human1.27563441
63MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.25118975
64SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.21636999
65E2F1_21310950_ChIP-Seq_MCF-7_Human1.17395856
66POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16428878
67NANOG_18555785_ChIP-Seq_MESCs_Mouse1.16388111
68CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.15271445
69SOX2_16153702_ChIP-ChIP_HESCs_Human1.14269093
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.14063913
71CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.13627329
72IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.11207708
73ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09857988
74NANOG_16153702_ChIP-ChIP_HESCs_Human1.07894377
75CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.07578713
76GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.06800962
77HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.06582694
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.05892843
79IRF1_19129219_ChIP-ChIP_H3396_Human1.04531007
80EWS_26573619_Chip-Seq_HEK293_Human1.03823819
81* SPI1_23547873_ChIP-Seq_NB4_Human1.03740432
82CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.03419217
83AR_21909140_ChIP-Seq_LNCAP_Human1.03414316
84* BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.02911282
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.02767212
86TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.01286857
87KDM5A_27292631_Chip-Seq_BREAST_Human0.98975280
88CTCF_18555785_ChIP-Seq_MESCs_Mouse0.97469275
89POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.96047365
90* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.95681945
91* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.92700034
92SRY_22984422_ChIP-ChIP_TESTIS_Rat0.91490409
93ZNF263_19887448_ChIP-Seq_K562_Human0.90175759
94CHD1_26751641_Chip-Seq_LNCaP_Human0.89062160
95POU5F1_16153702_ChIP-ChIP_HESCs_Human0.86897674
96* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86305102
97ESR1_15608294_ChIP-ChIP_MCF-7_Human0.84923600
98HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.84877411
99ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.82431606
100SALL1_21062744_ChIP-ChIP_HESCs_Human0.82061525
101* SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.81633991
102E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.77522959
103SOX2_18555785_ChIP-Seq_MESCs_Mouse0.77055412
104ELF5_23300383_ChIP-Seq_T47D_Human0.75496873
105STAT3_1855785_ChIP-Seq_MESCs_Mouse0.75041216
106NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.74848113
107* TFEB_21752829_ChIP-Seq_HELA_Human0.74683148
108TP63_17297297_ChIP-ChIP_HaCaT_Human0.74652534
109SOX17_20123909_ChIP-Seq_XEN_Mouse0.74317318
110PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.73565010
111RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.72051691
112STAT4_19710469_ChIP-ChIP_TH1__Mouse0.69777995
113FUS_26573619_Chip-Seq_HEK293_Human0.68241450
114TP63_19390658_ChIP-ChIP_HaCaT_Human0.67841165
115OCT4_18692474_ChIP-Seq_MEFs_Mouse0.66384785
116TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.66084725
117SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.65390766

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.65422817
2MP0003693_abnormal_embryo_hatching4.24140365
3MP0004957_abnormal_blastocyst_morpholog3.76139986
4MP0003123_paternal_imprinting2.93376810
5MP0008057_abnormal_DNA_replication2.91110140
6MP0003806_abnormal_nucleotide_metabolis2.82467595
7MP0010094_abnormal_chromosome_stability2.71912685
8MP0003077_abnormal_cell_cycle2.55402237
9MP0006054_spinal_hemorrhage2.30471168
10MP0008058_abnormal_DNA_repair2.23062660
11MP0008932_abnormal_embryonic_tissue2.05164056
12MP0001529_abnormal_vocalization1.96477518
13MP0003111_abnormal_nucleus_morphology1.96112379
14MP0002396_abnormal_hematopoietic_system1.89300586
15MP0003786_premature_aging1.88229073
16MP0008007_abnormal_cellular_replicative1.88088721
17MP0002163_abnormal_gland_morphology1.84730919
18MP0009697_abnormal_copulation1.82677259
19MP0003122_maternal_imprinting1.82185041
20MP0003763_abnormal_thymus_physiology1.70617530
21MP0000490_abnormal_crypts_of1.67503704
22MP0002938_white_spotting1.64227715
23MP0009333_abnormal_splenocyte_physiolog1.60766304
24MP0001293_anophthalmia1.59054364
25MP0002796_impaired_skin_barrier1.58240463
26MP0005174_abnormal_tail_pigmentation1.55708078
27MP0003121_genomic_imprinting1.54966383
28MP0005379_endocrine/exocrine_gland_phen1.54206691
29MP0003890_abnormal_embryonic-extraembry1.52036078
30MP0002638_abnormal_pupillary_reflex1.50212961
31MP0002095_abnormal_skin_pigmentation1.45599981
32MP0006292_abnormal_olfactory_placode1.44700925
33MP0001853_heart_inflammation1.43106695
34MP0006036_abnormal_mitochondrial_physio1.41671193
35MP0006276_abnormal_autonomic_nervous1.39226421
36MP0005380_embryogenesis_phenotype1.36946750
37MP0001672_abnormal_embryogenesis/_devel1.36946750
38MP0004808_abnormal_hematopoietic_stem1.36625730
39MP0003315_abnormal_perineum_morphology1.36395464
40MP0002254_reproductive_system_inflammat1.33492189
41MP0006072_abnormal_retinal_apoptosis1.30677416
42MP0002132_abnormal_respiratory_system1.30512570
43MP0003941_abnormal_skin_development1.29724335
44MP0001188_hyperpigmentation1.27754893
45MP0001986_abnormal_taste_sensitivity1.27614242
46MP0010234_abnormal_vibrissa_follicle1.26746860
47MP0001881_abnormal_mammary_gland1.25882558
48MP0006035_abnormal_mitochondrial_morpho1.24568690
49MP0002085_abnormal_embryonic_tissue1.24021766
50MP0003984_embryonic_growth_retardation1.22121530
51MP0005408_hypopigmentation1.18997853
52MP0002088_abnormal_embryonic_growth/wei1.17450087
53MP0005671_abnormal_response_to1.17100742
54MP0005075_abnormal_melanosome_morpholog1.16408746
55MP0000703_abnormal_thymus_morphology1.14213216
56MP0002398_abnormal_bone_marrow1.13984764
57MP0002084_abnormal_developmental_patter1.13814764
58MP0002697_abnormal_eye_size1.13162332
59MP0000372_irregular_coat_pigmentation1.12792920
60MP0009785_altered_susceptibility_to1.12071387
61MP0003186_abnormal_redox_activity1.11973930
62MP0002722_abnormal_immune_system1.11969200
63MP0001835_abnormal_antigen_presentation1.11476072
64MP0010030_abnormal_orbit_morphology1.10612567
65MP0004185_abnormal_adipocyte_glucose1.09767037
66MP0002009_preneoplasia1.07260574
67MP0000350_abnormal_cell_proliferation1.06640773
68MP0002210_abnormal_sex_determination1.06165538
69MP0003136_yellow_coat_color1.04534961
70MP0005084_abnormal_gallbladder_morpholo1.03983732
71MP0000689_abnormal_spleen_morphology1.03637902
72MP0004197_abnormal_fetal_growth/weight/1.03025229
73MP0003724_increased_susceptibility_to1.02989980
74MP0000762_abnormal_tongue_morphology1.01259447
75MP0002111_abnormal_tail_morphology1.01146136
76MP0004381_abnormal_hair_follicle1.00147347
77MP0002282_abnormal_trachea_morphology0.99920115
78MP0000358_abnormal_cell_content/0.98534796
79MP0002166_altered_tumor_susceptibility0.98359260
80MP0003937_abnormal_limbs/digits/tail_de0.97952708
81MP0002148_abnormal_hypersensitivity_rea0.97121236
82MP0001545_abnormal_hematopoietic_system0.96819495
83MP0005397_hematopoietic_system_phenotyp0.96819495
84MP0001905_abnormal_dopamine_level0.95997718
85MP0002277_abnormal_respiratory_mucosa0.95943310
86MP0000313_abnormal_cell_death0.95283396
87MP0001286_abnormal_eye_development0.94795559
88MP0000685_abnormal_immune_system0.94681019
89MP0002019_abnormal_tumor_incidence0.94207107
90MP0005220_abnormal_exocrine_pancreas0.92662664
91MP0002086_abnormal_extraembryonic_tissu0.92569932
92MP0002006_tumorigenesis0.92198744
93MP0002877_abnormal_melanocyte_morpholog0.90835005
94MP0010352_gastrointestinal_tract_polyps0.89817662
95MP0002429_abnormal_blood_cell0.88929331
96MP0004133_heterotaxia0.88312894
97MP0004147_increased_porphyrin_level0.87206916
98MP0002420_abnormal_adaptive_immunity0.86355785
99MP0001730_embryonic_growth_arrest0.85727223
100MP0002751_abnormal_autonomic_nervous0.85303318
101MP0001819_abnormal_immune_cell0.82722709
102MP0005389_reproductive_system_phenotype0.82275544
103MP0000716_abnormal_immune_system0.81461331
104MP0001145_abnormal_male_reproductive0.81436707
105MP0001800_abnormal_humoral_immune0.81147197
106MP0008877_abnormal_DNA_methylation0.80531106
107MP0002405_respiratory_system_inflammati0.80070854
108MP0003567_abnormal_fetal_cardiomyocyte0.79838924
109MP0000049_abnormal_middle_ear0.79828111
110MP0010386_abnormal_urinary_bladder0.79669912
111MP0009672_abnormal_birth_weight0.79650639
112MP0001919_abnormal_reproductive_system0.78959030
113MP0002160_abnormal_reproductive_system0.78947314
114MP0000627_abnormal_mammary_gland0.77306861
115MP0005000_abnormal_immune_tolerance0.77266208
116MP0000858_altered_metastatic_potential0.76483101
117MP0001873_stomach_inflammation0.75710882
118MP0005503_abnormal_tendon_morphology0.74746937
119MP0009250_abnormal_appendicular_skeleto0.74170562
120MP0003718_maternal_effect0.73872653
121MP0005645_abnormal_hypothalamus_physiol0.73274560
122MP0010307_abnormal_tumor_latency0.73233955
123MP0001727_abnormal_embryo_implantation0.72689265
124MP0005409_darkened_coat_color0.72620648
125MP0001697_abnormal_embryo_size0.72397951
126MP0008789_abnormal_olfactory_epithelium0.71641409
127MP0002723_abnormal_immune_serum0.71544966
128MP0001929_abnormal_gametogenesis0.71078414
129MP0003866_abnormal_defecation0.70885545
130MP0002102_abnormal_ear_morphology0.70106282
131MP0002452_abnormal_antigen_presenting0.69934810
132MP0005501_abnormal_skin_physiology0.69700107
133MP0000653_abnormal_sex_gland0.69344907
134MP0002693_abnormal_pancreas_physiology0.69077178
135MP0002080_prenatal_lethality0.69004760
136MP0003755_abnormal_palate_morphology0.68914032
137MP0000579_abnormal_nail_morphology0.68492535
138MP0002177_abnormal_outer_ear0.68429219
139MP0002060_abnormal_skin_morphology0.67804907
140MP0005171_absent_coat_pigmentation0.67667333
141MP0009053_abnormal_anal_canal0.63729324
142MP0003936_abnormal_reproductive_system0.63374888
143MP0001764_abnormal_homeostasis0.61954342
144MP0001186_pigmentation_phenotype0.60964302
145MP0001119_abnormal_female_reproductive0.60962515
146MP0002233_abnormal_nose_morphology0.60925912
147MP0005395_other_phenotype0.59726956
148MP0001340_abnormal_eyelid_morphology0.58486684

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)8.74930595
2Abnormal number of erythroid precursors (HP:0012131)7.91311472
3Reticulocytopenia (HP:0001896)6.59843800
4Macrocytic anemia (HP:0001972)5.33643531
5Pallor (HP:0000980)5.24796273
6Acute necrotizing encephalopathy (HP:0006965)4.93483608
7Mitochondrial inheritance (HP:0001427)4.58513530
8Abnormal mitochondria in muscle tissue (HP:0008316)4.50759079
9Aplastic anemia (HP:0001915)4.38215465
10Increased hepatocellular lipid droplets (HP:0006565)4.18841210
11Progressive macrocephaly (HP:0004481)4.00677172
12Increased CSF lactate (HP:0002490)3.89311720
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.73703694
14Decreased activity of mitochondrial respiratory chain (HP:0008972)3.73703694
15Acute encephalopathy (HP:0006846)3.70460455
16Hepatocellular necrosis (HP:0001404)3.68911148
17Lipid accumulation in hepatocytes (HP:0006561)3.60068282
1811 pairs of ribs (HP:0000878)3.54990033
19Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.50150029
20Renal Fanconi syndrome (HP:0001994)3.30651881
21Chromsome breakage (HP:0040012)3.24069099
22Aplasia/Hypoplasia of the sacrum (HP:0008517)3.23808864
23Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.18321511
24Exertional dyspnea (HP:0002875)3.17468538
25Colon cancer (HP:0003003)3.16717707
26Oral leukoplakia (HP:0002745)3.16058229
27Chromosomal breakage induced by crosslinking agents (HP:0003221)3.11676057
28Increased intramyocellular lipid droplets (HP:0012240)3.07473264
29Hepatic necrosis (HP:0002605)3.01132049
303-Methylglutaconic aciduria (HP:0003535)2.99060715
31Exercise intolerance (HP:0003546)2.98212269
32Respiratory difficulties (HP:0002880)2.96814553
33Meckel diverticulum (HP:0002245)2.93597481
34Abnormality of methionine metabolism (HP:0010901)2.90188410
35Type I transferrin isoform profile (HP:0003642)2.89874178
36Thrombocytosis (HP:0001894)2.89563810
37Hypoplasia of the pons (HP:0012110)2.88647712
38Amniotic constriction ring (HP:0009775)2.83330810
39Abnormality of placental membranes (HP:0011409)2.83330810
40Abnormality of the pons (HP:0007361)2.81140793
41Abnormality of the ileum (HP:0001549)2.78655297
42Increased serum lactate (HP:0002151)2.75344983
43Abnormality of chromosome stability (HP:0003220)2.73405282
44Irregular epiphyses (HP:0010582)2.64504054
45Aplasia/Hypoplasia of the uvula (HP:0010293)2.59991594
46Abnormal hemoglobin (HP:0011902)2.57347538
47Megaloblastic anemia (HP:0001889)2.55811889
48Birth length less than 3rd percentile (HP:0003561)2.54937361
49Homocystinuria (HP:0002156)2.51110823
50Abnormality of homocysteine metabolism (HP:0010919)2.51110823
51Lactic acidosis (HP:0003128)2.46513593
52Glossoptosis (HP:0000162)2.45082195
53Increased muscle lipid content (HP:0009058)2.40136778
54Abnormality of the heme biosynthetic pathway (HP:0010472)2.38456815
55Congenital, generalized hypertrichosis (HP:0004540)2.37197523
56Depressed nasal ridge (HP:0000457)2.37158238
57Abnormality of serum amino acid levels (HP:0003112)2.36572716
58Progressive muscle weakness (HP:0003323)2.35355420
59Respiratory failure (HP:0002878)2.33527818
60Microvesicular hepatic steatosis (HP:0001414)2.30892917
61Methylmalonic acidemia (HP:0002912)2.30565647
62Rough bone trabeculation (HP:0100670)2.28302110
63Cerebral edema (HP:0002181)2.25300530
64Squamous cell carcinoma (HP:0002860)2.22225105
65Stenosis of the external auditory canal (HP:0000402)2.20996420
66Abnormal protein glycosylation (HP:0012346)2.16689333
67Abnormal glycosylation (HP:0012345)2.16689333
68Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.16689333
69Abnormal protein N-linked glycosylation (HP:0012347)2.16689333
70Microretrognathia (HP:0000308)2.16644527
71Septo-optic dysplasia (HP:0100842)2.16007515
72Optic disc pallor (HP:0000543)2.15310888
73IgM deficiency (HP:0002850)2.13141036
74Hypothermia (HP:0002045)2.12477309
75Absent thumb (HP:0009777)2.12018076
76Abnormality of aspartate family amino acid metabolism (HP:0010899)2.11006649
77Carpal bone hypoplasia (HP:0001498)2.10759439
78Abnormality of alanine metabolism (HP:0010916)2.08886618
79Hyperalaninemia (HP:0003348)2.08886618
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.08886618
81Methylmalonic aciduria (HP:0012120)2.08518912
82Small intestinal stenosis (HP:0012848)2.07054211
83Duodenal stenosis (HP:0100867)2.07054211
84Abnormality of reticulocytes (HP:0004312)2.06761678
85Abnormal lung lobation (HP:0002101)2.06077923
86Asplenia (HP:0001746)2.04724684
87Trismus (HP:0000211)1.99230120
88Sparse eyelashes (HP:0000653)1.97860840
89Abnormality of renal resorption (HP:0011038)1.97451498
90Pancytopenia (HP:0001876)1.97435153
91Horseshoe kidney (HP:0000085)1.96846791
92Testicular atrophy (HP:0000029)1.96675760
93Missing ribs (HP:0000921)1.95418752
94Premature graying of hair (HP:0002216)1.94004807
95Progressive external ophthalmoplegia (HP:0000590)1.92407126
96Leukodystrophy (HP:0002415)1.92244915
97Abnormality of the axillary hair (HP:0100134)1.91187521
98Abnormality of secondary sexual hair (HP:0009888)1.91187521
99IgA deficiency (HP:0002720)1.89794319
100Selective tooth agenesis (HP:0001592)1.87755839
101Sensory axonal neuropathy (HP:0003390)1.87611278
102Reduced antithrombin III activity (HP:0001976)1.85044277
103Abnormal number of incisors (HP:0011064)1.84628666
104Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.84579496
105Lethargy (HP:0001254)1.82406397
106Aplasia/Hypoplasia of the spleen (HP:0010451)1.81462426
107Muscle fiber atrophy (HP:0100295)1.75707394
108Abnormality of the carotid arteries (HP:0005344)1.75460148
109Neoplasm of the colon (HP:0100273)1.74973839
110Migraine (HP:0002076)1.74628907
111Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.74321021
112Myelodysplasia (HP:0002863)1.73280668
113Abnormality of sulfur amino acid metabolism (HP:0004339)1.72760303
114Tracheoesophageal fistula (HP:0002575)1.72164155
115Hyperphosphaturia (HP:0003109)1.71421569
116Increased serum pyruvate (HP:0003542)1.69626584
117Hypoplasia of the radius (HP:0002984)1.69151671
118Aplasia/hypoplasia of the uterus (HP:0008684)1.68192233
119Cellular immunodeficiency (HP:0005374)1.67933671
120Thick lower lip vermilion (HP:0000179)1.66403343
121Severe visual impairment (HP:0001141)1.64494593
122Triphalangeal thumb (HP:0001199)1.64010166
123Genu varum (HP:0002970)1.63252631
124Partial duplication of thumb phalanx (HP:0009944)1.61791570
125Woolly hair (HP:0002224)1.59548654
126Abnormality of the preputium (HP:0100587)1.57464505
127Type 2 muscle fiber atrophy (HP:0003554)1.56490666
128Breast hypoplasia (HP:0003187)1.55873576
129Metaphyseal dysplasia (HP:0100255)1.55535090
130Emotional lability (HP:0000712)1.54828055
131Abnormal trabecular bone morphology (HP:0100671)1.53903814
132Multiple enchondromatosis (HP:0005701)1.52973631
133Partial duplication of the phalanx of hand (HP:0009999)1.52381011
134Facial cleft (HP:0002006)1.52285661
135True hermaphroditism (HP:0010459)1.51360592
136Cleft eyelid (HP:0000625)1.50306177
137Neoplasm of the pancreas (HP:0002894)1.46889602
138Lymphoma (HP:0002665)1.46072816
139Parakeratosis (HP:0001036)1.44429770

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.74325570
2VRK23.94156833
3STK163.75401549
4WEE13.44727166
5BUB13.41256946
6ZAK3.17512661
7VRK13.13913535
8EIF2AK12.75503549
9TAF12.54486401
10EIF2AK32.53266748
11TTK2.51076074
12NEK12.46658995
13NME12.45019289
14MAP3K122.41226913
15MST42.28990254
16RPS6KB22.26503944
17PASK2.24685050
18SRPK12.14983518
19PIM22.08890820
20CDC72.04101023
21ACVR1B1.85505484
22BRSK21.76520488
23TGFBR11.75782086
24MKNK11.73651353
25TNIK1.55100505
26CDK191.51684001
27TSSK61.51192600
28DYRK31.47334289
29LRRK21.45847562
30TLK11.41492539
31TEC1.35291309
32CDK81.32625379
33NUAK11.27406922
34MAPKAPK31.27181454
35FLT31.24377673
36WNK41.20744449
37STK391.20744030
38AURKB1.14160093
39GRK71.09089737
40PLK41.04819404
41ADRBK21.03621807
42MAPKAPK51.00880954
43MUSK1.00208442
44SCYL20.98812598
45TESK20.98789552
46CDK70.97100634
47MAPK150.94799517
48PIK3CG0.94490497
49STK240.94303873
50PLK10.94216839
51SMG10.93289141
52MKNK20.90978332
53ARAF0.90719352
54STK30.90649065
55MAP4K10.89239594
56MYLK0.89153905
57AURKA0.88683079
58KDR0.87965694
59BTK0.87324518
60STK40.84832561
61CSNK2A20.84582309
62PDK20.84346255
63ALK0.83123771
64ILK0.81206668
65PBK0.81119325
66PLK30.81046030
67BMPR1B0.79969375
68IRAK30.79288627
69MAP3K90.76985618
70CSNK2A10.76922466
71MAP3K110.76713578
72RPS6KA40.76584963
73TESK10.75678958
74MAP3K30.73978142
75CCNB10.72673080
76STK38L0.71496428
77ATR0.71293226
78MAP3K100.69963662
79IRAK40.69797208
80DAPK30.69783309
81NLK0.68743393
82MST1R0.68646610
83KIT0.68192782
84EIF2AK20.67721605
85TXK0.67249969
86BRSK10.63618044
87LATS20.63347054
88PAK40.61934912
89RPS6KA50.61810274
90ERBB40.60450577
91ATM0.59989724
92SYK0.57640266
93MAP2K60.56929569
94PNCK0.55534390
95BRAF0.54580628
96MAP2K30.53967423
97GRK60.53071101
98LYN0.52565298
99CAMKK20.52408230
100LIMK10.49072332
101CDK40.48662314
102OXSR10.48518836
103CDK30.48223238
104DYRK20.46866670
105NEK20.46633554
106PIM10.46175225
107DAPK10.44306012
108ZAP700.43878771
109YES10.43777112
110ADRBK10.43622859
111CSNK1E0.43059205
112BCKDK0.42571645
113PRKCI0.42415174
114IKBKB0.41588652
115EEF2K0.40235025
116FGFR10.39997458
117CDK10.39775611
118TNK20.39592140
119MAP3K80.39453013
120ABL20.38341916
121CDK20.37692853
122STK100.36778471
123MAP2K20.36669453
124CHEK20.35854058
125RAF10.35215493
126PAK20.35018309
127MELK0.34492938
128ERBB30.32883080
129GRK10.32878650
130CDK60.30976364
131LCK0.30975898
132PAK10.30966599
133IRAK10.30583062
134AKT20.29989747
135CHEK10.28566203
136CSNK1G10.26465408
137PRKDC0.23266239
138CLK10.20315269
139NEK90.18483756
140LATS10.18372632
141CDK90.17573455

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030107.16100481
2Proteasome_Homo sapiens_hsa030504.02692743
3Oxidative phosphorylation_Homo sapiens_hsa001903.68750951
4DNA replication_Homo sapiens_hsa030303.43915299
5Protein export_Homo sapiens_hsa030603.33584059
6Parkinsons disease_Homo sapiens_hsa050123.33275359
7RNA polymerase_Homo sapiens_hsa030203.33006978
8Mismatch repair_Homo sapiens_hsa034302.95368931
9Spliceosome_Homo sapiens_hsa030402.81161979
10Huntingtons disease_Homo sapiens_hsa050162.52317810
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.44541935
12Pyrimidine metabolism_Homo sapiens_hsa002402.37723012
13Alzheimers disease_Homo sapiens_hsa050102.30559234
14Nucleotide excision repair_Homo sapiens_hsa034202.30217614
15Homologous recombination_Homo sapiens_hsa034402.11042432
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.01164249
17RNA transport_Homo sapiens_hsa030131.87338225
18Base excision repair_Homo sapiens_hsa034101.86781955
19RNA degradation_Homo sapiens_hsa030181.67350539
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.48647728
21Non-homologous end-joining_Homo sapiens_hsa034501.42624844
22Basal transcription factors_Homo sapiens_hsa030221.37789987
23Selenocompound metabolism_Homo sapiens_hsa004501.35733715
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.33250229
25Cell cycle_Homo sapiens_hsa041101.29869508
26Purine metabolism_Homo sapiens_hsa002301.27653609
27Fanconi anemia pathway_Homo sapiens_hsa034601.27214508
28Pyruvate metabolism_Homo sapiens_hsa006201.25861918
29One carbon pool by folate_Homo sapiens_hsa006701.09187010
30Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.06681417
31Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02374609
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02324894
33Vitamin B6 metabolism_Homo sapiens_hsa007500.98404446
34Cardiac muscle contraction_Homo sapiens_hsa042600.94680630
35p53 signaling pathway_Homo sapiens_hsa041150.93070144
36Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.87338230
37N-Glycan biosynthesis_Homo sapiens_hsa005100.87269241
38Folate biosynthesis_Homo sapiens_hsa007900.86859837
39Epstein-Barr virus infection_Homo sapiens_hsa051690.83918790
40SNARE interactions in vesicular transport_Homo sapiens_hsa041300.80856278
41Antigen processing and presentation_Homo sapiens_hsa046120.78417618
42Primary immunodeficiency_Homo sapiens_hsa053400.77541195
43Propanoate metabolism_Homo sapiens_hsa006400.77264601
44Systemic lupus erythematosus_Homo sapiens_hsa053220.76679251
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.75903234
46Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74669293
47Biosynthesis of amino acids_Homo sapiens_hsa012300.74006063
48Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.72891766
49Cyanoamino acid metabolism_Homo sapiens_hsa004600.72760605
50Vitamin digestion and absorption_Homo sapiens_hsa049770.68673149
51mRNA surveillance pathway_Homo sapiens_hsa030150.64887703
52Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.63065974
53Sulfur relay system_Homo sapiens_hsa041220.62604104
54Vibrio cholerae infection_Homo sapiens_hsa051100.62283845
55Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61666005
56Carbon metabolism_Homo sapiens_hsa012000.57420555
57Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54369028
58Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54043121
59Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.53111185
60Hematopoietic cell lineage_Homo sapiens_hsa046400.52840755
61Glutathione metabolism_Homo sapiens_hsa004800.51860950
62Alcoholism_Homo sapiens_hsa050340.51582399
63Herpes simplex infection_Homo sapiens_hsa051680.49217392
64Metabolic pathways_Homo sapiens_hsa011000.46860224
65Hedgehog signaling pathway_Homo sapiens_hsa043400.44671700
66Steroid biosynthesis_Homo sapiens_hsa001000.43608017
67Basal cell carcinoma_Homo sapiens_hsa052170.43318191
68Arachidonic acid metabolism_Homo sapiens_hsa005900.42566869
69Legionellosis_Homo sapiens_hsa051340.42518712
702-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.41411699
71Viral carcinogenesis_Homo sapiens_hsa052030.34930970
72Allograft rejection_Homo sapiens_hsa053300.34716443
73Thyroid cancer_Homo sapiens_hsa052160.34249002
74Maturity onset diabetes of the young_Homo sapiens_hsa049500.34239156
75Oocyte meiosis_Homo sapiens_hsa041140.33220483
76Collecting duct acid secretion_Homo sapiens_hsa049660.33209291
77Type I diabetes mellitus_Homo sapiens_hsa049400.33104075
78Asthma_Homo sapiens_hsa053100.32458658
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30192012
80Graft-versus-host disease_Homo sapiens_hsa053320.29863610
81HTLV-I infection_Homo sapiens_hsa051660.26679297
82Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.24339103
83Shigellosis_Homo sapiens_hsa051310.22525119
84Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22216946
85Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21468185
86Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.20996459
87Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.20849013
88Arginine and proline metabolism_Homo sapiens_hsa003300.20815336
89Pentose phosphate pathway_Homo sapiens_hsa000300.20435621
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.20232991
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.19780909
92Wnt signaling pathway_Homo sapiens_hsa043100.19325811
93Hippo signaling pathway_Homo sapiens_hsa043900.19148660
94Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.18517948
95Measles_Homo sapiens_hsa051620.18419869
96Cysteine and methionine metabolism_Homo sapiens_hsa002700.17236849
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.16884742
98Hepatitis B_Homo sapiens_hsa051610.16788266
99Fatty acid elongation_Homo sapiens_hsa000620.16166926
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.15889876
101Rheumatoid arthritis_Homo sapiens_hsa053230.15755871
102Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.15268427
103Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.15263155
104Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.14191253
105Galactose metabolism_Homo sapiens_hsa000520.14180119
106Intestinal immune network for IgA production_Homo sapiens_hsa046720.14096239
107Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.13791233
108Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.13546614
109Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.13266614
110Fructose and mannose metabolism_Homo sapiens_hsa000510.12954599
111Other glycan degradation_Homo sapiens_hsa005110.12916519
112Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.12881314
113Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.12454939
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11845173
115RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.11324247
116Small cell lung cancer_Homo sapiens_hsa052220.11109708
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.10765715
118NOD-like receptor signaling pathway_Homo sapiens_hsa046210.10342121
119TGF-beta signaling pathway_Homo sapiens_hsa043500.10289675
120Protein digestion and absorption_Homo sapiens_hsa049740.10128223
121Fatty acid degradation_Homo sapiens_hsa000710.09588667
122Autoimmune thyroid disease_Homo sapiens_hsa053200.08305418
123Melanoma_Homo sapiens_hsa052180.07671963
124Serotonergic synapse_Homo sapiens_hsa047260.07496858
125Linoleic acid metabolism_Homo sapiens_hsa005910.07285350
126Apoptosis_Homo sapiens_hsa042100.06933324
127Peroxisome_Homo sapiens_hsa041460.06799548
128Tryptophan metabolism_Homo sapiens_hsa003800.06773088
129Sphingolipid metabolism_Homo sapiens_hsa006000.06505880
130Sulfur metabolism_Homo sapiens_hsa009200.06359773
131Caffeine metabolism_Homo sapiens_hsa002320.05167828
132Pertussis_Homo sapiens_hsa051330.04977041
133Pancreatic secretion_Homo sapiens_hsa049720.04454693
134Renin-angiotensin system_Homo sapiens_hsa046140.04069172
135Tyrosine metabolism_Homo sapiens_hsa003500.03250688
136Chemical carcinogenesis_Homo sapiens_hsa052040.03235198
137Fatty acid metabolism_Homo sapiens_hsa012120.01009282
138Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512-0.0162009
139beta-Alanine metabolism_Homo sapiens_hsa00410-0.0019885

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