

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 9.57793778 |
| 2 | negative regulation of cAMP-mediated signaling (GO:0043951) | 8.36295279 |
| 3 | regulation of translational termination (GO:0006449) | 8.02917598 |
| 4 | opioid receptor signaling pathway (GO:0038003) | 7.51087879 |
| 5 | behavioral response to ethanol (GO:0048149) | 6.76502767 |
| 6 | ether lipid metabolic process (GO:0046485) | 6.26457813 |
| 7 | piRNA metabolic process (GO:0034587) | 6.25555406 |
| 8 | adult feeding behavior (GO:0008343) | 6.08052026 |
| 9 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 5.96222266 |
| 10 | regulation of acrosome reaction (GO:0060046) | 5.73370526 |
| 11 | mRNA cleavage (GO:0006379) | 5.60009241 |
| 12 | N-terminal protein amino acid acetylation (GO:0006474) | 5.10419882 |
| 13 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 5.04846616 |
| 14 | sphingosine metabolic process (GO:0006670) | 4.99183259 |
| 15 | ncRNA catabolic process (GO:0034661) | 4.85767182 |
| 16 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 4.85480491 |
| 17 | response to pheromone (GO:0019236) | 4.67575980 |
| 18 | diol metabolic process (GO:0034311) | 4.61636936 |
| 19 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 4.54030567 |
| 20 | positive regulation of cAMP-mediated signaling (GO:0043950) | 4.52289300 |
| 21 | sphingoid metabolic process (GO:0046519) | 4.46718750 |
| 22 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.45033484 |
| 23 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.45033484 |
| 24 | glycerol ether metabolic process (GO:0006662) | 4.32734873 |
| 25 | cytokinetic process (GO:0032506) | 4.31328527 |
| 26 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 4.26642973 |
| 27 | thrombin receptor signaling pathway (GO:0070493) | 4.22097608 |
| 28 | apoptotic DNA fragmentation (GO:0006309) | 4.06687031 |
| 29 | notochord development (GO:0030903) | 4.04783496 |
| 30 | ether metabolic process (GO:0018904) | 3.98609883 |
| 31 | regulation of protein glycosylation (GO:0060049) | 3.96436226 |
| 32 | regulation of translational elongation (GO:0006448) | 3.88443407 |
| 33 | positive regulation of muscle cell apoptotic process (GO:0010661) | 3.82825474 |
| 34 | DNA deamination (GO:0045006) | 3.75508876 |
| 35 | sensory perception of smell (GO:0007608) | 3.66808317 |
| 36 | positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968) | 3.64983307 |
| 37 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.55892749 |
| 38 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 3.54005919 |
| 39 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.51532189 |
| 40 | replicative senescence (GO:0090399) | 3.39951727 |
| 41 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 3.34598905 |
| 42 | pseudouridine synthesis (GO:0001522) | 3.31781810 |
| 43 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 3.27742568 |
| 44 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 3.26624499 |
| 45 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.25243929 |
| 46 | rhodopsin mediated signaling pathway (GO:0016056) | 3.23973374 |
| 47 | glomerular visceral epithelial cell development (GO:0072015) | 3.20225959 |
| 48 | negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) | 3.15720407 |
| 49 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 3.14839366 |
| 50 | sister chromatid cohesion (GO:0007062) | 3.12294297 |
| 51 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.09932084 |
| 52 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.08198159 |
| 53 | negative regulation of interleukin-8 production (GO:0032717) | 3.00184929 |
| 54 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.96611728 |
| 55 | positive regulation of fatty acid transport (GO:2000193) | 2.96570076 |
| 56 | N-terminal protein amino acid modification (GO:0031365) | 2.91202883 |
| 57 | positive regulation of immune response to tumor cell (GO:0002839) | 2.89530566 |
| 58 | regulation of immune response to tumor cell (GO:0002837) | 2.89530566 |
| 59 | regulation of response to tumor cell (GO:0002834) | 2.89530566 |
| 60 | positive regulation of response to tumor cell (GO:0002836) | 2.89530566 |
| 61 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.89378272 |
| 62 | ribonucleoprotein complex disassembly (GO:0032988) | 2.88611131 |
| 63 | positive regulation of icosanoid secretion (GO:0032305) | 2.88168454 |
| 64 | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | 2.88052968 |
| 65 | replication fork processing (GO:0031297) | 2.85772812 |
| 66 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.85755056 |
| 67 | cellular response to alkaloid (GO:0071312) | 2.85351301 |
| 68 | cellular response to ammonium ion (GO:0071242) | 2.85126428 |
| 69 | G-protein coupled receptor internalization (GO:0002031) | 2.84387686 |
| 70 | DNA synthesis involved in DNA repair (GO:0000731) | 2.83680233 |
| 71 | cornea development in camera-type eye (GO:0061303) | 2.83208174 |
| 72 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.82512991 |
| 73 | sulfate transport (GO:0008272) | 2.81898143 |
| 74 | rRNA modification (GO:0000154) | 2.81852433 |
| 75 | regulation of smooth muscle cell apoptotic process (GO:0034391) | 2.81306173 |
| 76 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.80599004 |
| 77 | coenzyme catabolic process (GO:0009109) | 2.80247723 |
| 78 | quinone biosynthetic process (GO:1901663) | 2.79675402 |
| 79 | viral mRNA export from host cell nucleus (GO:0046784) | 2.79208824 |
| 80 | regulation of cAMP-mediated signaling (GO:0043949) | 2.76588710 |
| 81 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.76588132 |
| 82 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.76091403 |
| 83 | glomerular epithelial cell development (GO:0072310) | 2.74104510 |
| 84 | rRNA methylation (GO:0031167) | 2.67748541 |
| 85 | rRNA catabolic process (GO:0016075) | 2.66436912 |
| 86 | regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) | 2.62726859 |
| 87 | gene silencing by RNA (GO:0031047) | 2.61091647 |
| 88 | resolution of meiotic recombination intermediates (GO:0000712) | 2.58093045 |
| 89 | regulation of female receptivity (GO:0045924) | 2.55487815 |
| 90 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.53445562 |
| 91 | regulation of glutamate receptor signaling pathway (GO:1900449) | 2.51516046 |
| 92 | recombinational repair (GO:0000725) | 2.51161105 |
| 93 | vitamin catabolic process (GO:0009111) | 2.51023294 |
| 94 | fat-soluble vitamin catabolic process (GO:0042363) | 2.51023294 |
| 95 | double-strand break repair via homologous recombination (GO:0000724) | 2.50848841 |
| 96 | positive regulation of Rho protein signal transduction (GO:0035025) | 2.50121691 |
| 97 | glyoxylate metabolic process (GO:0046487) | 2.49434565 |
| 98 | keratinocyte proliferation (GO:0043616) | 2.47601288 |
| 99 | L-fucose catabolic process (GO:0042355) | 2.44669166 |
| 100 | L-fucose metabolic process (GO:0042354) | 2.44669166 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.20212557 |
| 2 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.80275618 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.61918674 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.57652490 |
| 5 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.98471357 |
| 6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.89216345 |
| 7 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.81980897 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.79464365 |
| 9 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.71655335 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.44618404 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.39463284 |
| 12 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.36095594 |
| 13 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.30875768 |
| 14 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.05846011 |
| 15 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.04665938 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.03186828 |
| 17 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.99406297 |
| 18 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.95327796 |
| 19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.92809036 |
| 20 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.88068137 |
| 21 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.87601065 |
| 22 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.84395659 |
| 23 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.84395659 |
| 24 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.83955514 |
| 25 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.82403969 |
| 26 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.78206491 |
| 27 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.78206491 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.75830504 |
| 29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.75734198 |
| 30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.72527938 |
| 31 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.67566947 |
| 32 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.66804005 |
| 33 | RXR_22108803_ChIP-Seq_LS180_Human | 1.60516913 |
| 34 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.60240719 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.59650956 |
| 36 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.59221498 |
| 37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.57096635 |
| 38 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.51245551 |
| 39 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.51195492 |
| 40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.48831980 |
| 41 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.47249439 |
| 42 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.40630770 |
| 43 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.38294213 |
| 44 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.37378680 |
| 45 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.36969824 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33199493 |
| 47 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.28954494 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.28945847 |
| 49 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.27535081 |
| 50 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.27023443 |
| 51 | TCF4_23295773_ChIP-Seq_U87_Human | 1.25593033 |
| 52 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.25322828 |
| 53 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.25322828 |
| 54 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.21659178 |
| 55 | STAT3_23295773_ChIP-Seq_U87_Human | 1.20401843 |
| 56 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.19726114 |
| 57 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.19726091 |
| 58 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.18721520 |
| 59 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.18361336 |
| 60 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.17337467 |
| 61 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.17052366 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.16677737 |
| 63 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.16067712 |
| 64 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.15903629 |
| 65 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.15082714 |
| 66 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.14144059 |
| 67 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.13367060 |
| 68 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10455766 |
| 69 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.10155773 |
| 70 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.09332426 |
| 71 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.07827803 |
| 72 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.06525433 |
| 73 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.06396836 |
| 74 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.05115908 |
| 75 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02354218 |
| 76 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.02326338 |
| 77 | CBP_21632823_ChIP-Seq_H3396_Human | 1.01498354 |
| 78 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.00600446 |
| 79 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.00030418 |
| 80 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.99712020 |
| 81 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.99712020 |
| 82 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.99301881 |
| 83 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.98619182 |
| 84 | P300_19829295_ChIP-Seq_ESCs_Human | 0.98203957 |
| 85 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.98000404 |
| 86 | ERA_21632823_ChIP-Seq_H3396_Human | 0.97291004 |
| 87 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.96834963 |
| 88 | TP53_16413492_ChIP-PET_HCT116_Human | 0.95905215 |
| 89 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.95481397 |
| 90 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.95372909 |
| 91 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.94220641 |
| 92 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.94215356 |
| 93 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.93634808 |
| 94 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.93358040 |
| 95 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.93295231 |
| 96 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.92632113 |
| 97 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90613304 |
| 98 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 0.89381795 |
| 99 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.88679912 |
| 100 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.87923804 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009278_abnormal_bone_marrow | 4.49257591 |
| 2 | MP0002876_abnormal_thyroid_physiology | 4.26977930 |
| 3 | MP0009780_abnormal_chondrocyte_physiolo | 3.98340350 |
| 4 | MP0005360_urolithiasis | 3.23229030 |
| 5 | MP0000569_abnormal_digit_pigmentation | 3.07249405 |
| 6 | MP0003183_abnormal_peptide_metabolism | 3.00024365 |
| 7 | MP0001968_abnormal_touch/_nociception | 2.86793104 |
| 8 | MP0006035_abnormal_mitochondrial_morpho | 2.82570939 |
| 9 | MP0003646_muscle_fatigue | 2.71181290 |
| 10 | MP0005551_abnormal_eye_electrophysiolog | 2.68014904 |
| 11 | MP0001545_abnormal_hematopoietic_system | 2.54620357 |
| 12 | MP0005397_hematopoietic_system_phenotyp | 2.54620357 |
| 13 | MP0010234_abnormal_vibrissa_follicle | 2.51428353 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 2.34549644 |
| 15 | MP0005503_abnormal_tendon_morphology | 2.26340032 |
| 16 | MP0005670_abnormal_white_adipose | 2.18469814 |
| 17 | MP0008057_abnormal_DNA_replication | 2.15322533 |
| 18 | MP0010094_abnormal_chromosome_stability | 2.11209048 |
| 19 | MP0009333_abnormal_splenocyte_physiolog | 2.09238937 |
| 20 | MP0006036_abnormal_mitochondrial_physio | 1.93786635 |
| 21 | MP0009764_decreased_sensitivity_to | 1.86233088 |
| 22 | MP0003941_abnormal_skin_development | 1.82800114 |
| 23 | MP0004147_increased_porphyrin_level | 1.80920369 |
| 24 | MP0003806_abnormal_nucleotide_metabolis | 1.79431487 |
| 25 | MP0000015_abnormal_ear_pigmentation | 1.74584367 |
| 26 | MP0008872_abnormal_physiological_respon | 1.74164858 |
| 27 | MP0000681_abnormal_thyroid_gland | 1.73405846 |
| 28 | MP0000678_abnormal_parathyroid_gland | 1.70981218 |
| 29 | MP0005645_abnormal_hypothalamus_physiol | 1.67135251 |
| 30 | MP0003880_abnormal_central_pattern | 1.55710168 |
| 31 | MP0001881_abnormal_mammary_gland | 1.55191268 |
| 32 | MP0008058_abnormal_DNA_repair | 1.54459377 |
| 33 | MP0003693_abnormal_embryo_hatching | 1.51747619 |
| 34 | MP0002971_abnormal_brown_adipose | 1.51134979 |
| 35 | MP0002733_abnormal_thermal_nociception | 1.50316172 |
| 36 | MP0003638_abnormal_response/metabolism_ | 1.47403104 |
| 37 | MP0002095_abnormal_skin_pigmentation | 1.45912405 |
| 38 | MP0003045_fibrosis | 1.45065934 |
| 39 | MP0001501_abnormal_sleep_pattern | 1.37200129 |
| 40 | MP0000685_abnormal_immune_system | 1.36503240 |
| 41 | MP0009697_abnormal_copulation | 1.34731660 |
| 42 | MP0003950_abnormal_plasma_membrane | 1.34098544 |
| 43 | MP0001873_stomach_inflammation | 1.30677144 |
| 44 | MP0001919_abnormal_reproductive_system | 1.29893592 |
| 45 | MP0003252_abnormal_bile_duct | 1.28522691 |
| 46 | MP0005085_abnormal_gallbladder_physiolo | 1.26010402 |
| 47 | MP0001664_abnormal_digestion | 1.24146580 |
| 48 | MP0003011_delayed_dark_adaptation | 1.19502383 |
| 49 | MP0005174_abnormal_tail_pigmentation | 1.19465340 |
| 50 | MP0004957_abnormal_blastocyst_morpholog | 1.13342189 |
| 51 | MP0004043_abnormal_pH_regulation | 1.13105582 |
| 52 | MP0005257_abnormal_intraocular_pressure | 1.11209569 |
| 53 | MP0001790_abnormal_immune_system | 1.08908395 |
| 54 | MP0005387_immune_system_phenotype | 1.08908395 |
| 55 | MP0003195_calcinosis | 1.07621304 |
| 56 | MP0009745_abnormal_behavioral_response | 1.06556403 |
| 57 | MP0008775_abnormal_heart_ventricle | 1.04440047 |
| 58 | MP0005253_abnormal_eye_physiology | 1.04205970 |
| 59 | MP0003936_abnormal_reproductive_system | 1.01973517 |
| 60 | MP0000358_abnormal_cell_content/ | 0.99688570 |
| 61 | MP0003718_maternal_effect | 0.98943437 |
| 62 | MP0008961_abnormal_basal_metabolism | 0.96246439 |
| 63 | MP0005646_abnormal_pituitary_gland | 0.93079498 |
| 64 | MP0002148_abnormal_hypersensitivity_rea | 0.92839541 |
| 65 | MP0001986_abnormal_taste_sensitivity | 0.90444692 |
| 66 | MP0005310_abnormal_salivary_gland | 0.90052382 |
| 67 | MP0000627_abnormal_mammary_gland | 0.89035792 |
| 68 | MP0002160_abnormal_reproductive_system | 0.84263117 |
| 69 | MP0005389_reproductive_system_phenotype | 0.83991830 |
| 70 | MP0001486_abnormal_startle_reflex | 0.83955126 |
| 71 | MP0000427_abnormal_hair_cycle | 0.83337110 |
| 72 | MP0009046_muscle_twitch | 0.82741831 |
| 73 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81600082 |
| 74 | MP0001929_abnormal_gametogenesis | 0.80597877 |
| 75 | MP0002796_impaired_skin_barrier | 0.79893842 |
| 76 | MP0003937_abnormal_limbs/digits/tail_de | 0.79289212 |
| 77 | MP0005365_abnormal_bile_salt | 0.77854319 |
| 78 | MP0005195_abnormal_posterior_eye | 0.76039082 |
| 79 | MP0003959_abnormal_lean_body | 0.75888799 |
| 80 | MP0005671_abnormal_response_to | 0.75741438 |
| 81 | MP0003077_abnormal_cell_cycle | 0.75009136 |
| 82 | MP0005410_abnormal_fertilization | 0.74925620 |
| 83 | MP0003633_abnormal_nervous_system | 0.73887143 |
| 84 | MP0002938_white_spotting | 0.73142588 |
| 85 | MP0002254_reproductive_system_inflammat | 0.72577418 |
| 86 | MP0002272_abnormal_nervous_system | 0.72099707 |
| 87 | MP0003172_abnormal_lysosome_physiology | 0.71301814 |
| 88 | MP0002970_abnormal_white_adipose | 0.70866698 |
| 89 | MP0002332_abnormal_exercise_endurance | 0.70394519 |
| 90 | MP0004742_abnormal_vestibular_system | 0.70128507 |
| 91 | MP0009765_abnormal_xenobiotic_induced | 0.69396840 |
| 92 | MP0002098_abnormal_vibrissa_morphology | 0.67771320 |
| 93 | MP0008875_abnormal_xenobiotic_pharmacok | 0.66402555 |
| 94 | MP0003786_premature_aging | 0.62376807 |
| 95 | MP0005167_abnormal_blood-brain_barrier | 0.62319266 |
| 96 | MP0001970_abnormal_pain_threshold | 0.61661234 |
| 97 | MP0010678_abnormal_skin_adnexa | 0.61596853 |
| 98 | MP0005330_cardiomyopathy | 0.59983962 |
| 99 | MP0002249_abnormal_larynx_morphology | 0.58579837 |
| 100 | MP0005332_abnormal_amino_acid | 0.56536908 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Thyroid-stimulating hormone excess (HP:0002925) | 8.74063011 |
| 2 | Volvulus (HP:0002580) | 6.11476412 |
| 3 | Congenital stationary night blindness (HP:0007642) | 5.07440969 |
| 4 | Progressive inability to walk (HP:0002505) | 4.63341294 |
| 5 | Progressive external ophthalmoplegia (HP:0000590) | 4.54557654 |
| 6 | Intestinal atresia (HP:0011100) | 4.47073048 |
| 7 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.42915588 |
| 8 | Pancreatic islet-cell hyperplasia (HP:0004510) | 4.18631791 |
| 9 | Chromsome breakage (HP:0040012) | 3.95348055 |
| 10 | Abnormality of the ileum (HP:0001549) | 3.95123800 |
| 11 | Abnormality of the aortic arch (HP:0012303) | 3.82611693 |
| 12 | Large for gestational age (HP:0001520) | 3.76609949 |
| 13 | Sensory axonal neuropathy (HP:0003390) | 3.57006216 |
| 14 | Oligodontia (HP:0000677) | 3.44177603 |
| 15 | Clumsiness (HP:0002312) | 3.39324222 |
| 16 | Poor head control (HP:0002421) | 3.38283941 |
| 17 | Broad alveolar ridges (HP:0000187) | 3.22007298 |
| 18 | Thickened helices (HP:0000391) | 3.03801428 |
| 19 | Prostate neoplasm (HP:0100787) | 2.98727087 |
| 20 | Tented upper lip vermilion (HP:0010804) | 2.92435031 |
| 21 | Ragged-red muscle fibers (HP:0003200) | 2.91693646 |
| 22 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.90599256 |
| 23 | Supernumerary spleens (HP:0009799) | 2.89076825 |
| 24 | Mesangial abnormality (HP:0001966) | 2.82272289 |
| 25 | Large eyes (HP:0001090) | 2.81790126 |
| 26 | Inability to walk (HP:0002540) | 2.75452178 |
| 27 | Embryonal renal neoplasm (HP:0011794) | 2.75259463 |
| 28 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.72583488 |
| 29 | Gaze-evoked nystagmus (HP:0000640) | 2.69882797 |
| 30 | Abnormal pupillary function (HP:0007686) | 2.65895775 |
| 31 | Tubular atrophy (HP:0000092) | 2.64360435 |
| 32 | Hypoproteinemia (HP:0003075) | 2.62273358 |
| 33 | Hypoplasia of the pons (HP:0012110) | 2.60656009 |
| 34 | Progressive muscle weakness (HP:0003323) | 2.55343297 |
| 35 | Abnormality of the pons (HP:0007361) | 2.52823164 |
| 36 | Increased serum lactate (HP:0002151) | 2.48682314 |
| 37 | Poor speech (HP:0002465) | 2.48080528 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.46775568 |
| 39 | Focal motor seizures (HP:0011153) | 2.46016977 |
| 40 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.43052695 |
| 41 | Agitation (HP:0000713) | 2.42663219 |
| 42 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.42279072 |
| 43 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.42279072 |
| 44 | Hyperglycinemia (HP:0002154) | 2.41340214 |
| 45 | Impaired proprioception (HP:0010831) | 2.40786744 |
| 46 | Hepatocellular necrosis (HP:0001404) | 2.35931416 |
| 47 | Neonatal respiratory distress (HP:0002643) | 2.35609359 |
| 48 | Impulsivity (HP:0100710) | 2.31627260 |
| 49 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.25655940 |
| 50 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.24536974 |
| 51 | Premature ovarian failure (HP:0008209) | 2.22267501 |
| 52 | Broad-based gait (HP:0002136) | 2.22189331 |
| 53 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.21958531 |
| 54 | Epileptic encephalopathy (HP:0200134) | 2.18383991 |
| 55 | Increased CSF lactate (HP:0002490) | 2.17429569 |
| 56 | Meckel diverticulum (HP:0002245) | 2.17010932 |
| 57 | Dysphonia (HP:0001618) | 2.14826541 |
| 58 | Abnormality of the labia minora (HP:0012880) | 2.14753136 |
| 59 | Abnormality of the preputium (HP:0100587) | 2.14689698 |
| 60 | Agammaglobulinemia (HP:0004432) | 2.14588647 |
| 61 | Proximal tubulopathy (HP:0000114) | 2.13169857 |
| 62 | Oligodactyly (hands) (HP:0001180) | 2.12941016 |
| 63 | Hepatic necrosis (HP:0002605) | 2.12627406 |
| 64 | Pendular nystagmus (HP:0012043) | 2.10428302 |
| 65 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.09927180 |
| 66 | Asplenia (HP:0001746) | 2.07808180 |
| 67 | Gastrointestinal atresia (HP:0002589) | 2.02547343 |
| 68 | 3-Methylglutaconic aciduria (HP:0003535) | 2.00475912 |
| 69 | Wide intermamillary distance (HP:0006610) | 1.99046092 |
| 70 | Cerebellar dysplasia (HP:0007033) | 1.95735082 |
| 71 | Lissencephaly (HP:0001339) | 1.91147706 |
| 72 | Acute encephalopathy (HP:0006846) | 1.89207115 |
| 73 | Increased corneal curvature (HP:0100692) | 1.88647513 |
| 74 | Keratoconus (HP:0000563) | 1.88647513 |
| 75 | Duplicated collecting system (HP:0000081) | 1.88129958 |
| 76 | Chronic sinusitis (HP:0011109) | 1.87295090 |
| 77 | External ophthalmoplegia (HP:0000544) | 1.86788213 |
| 78 | Abnormality of glycine metabolism (HP:0010895) | 1.85212836 |
| 79 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.85212836 |
| 80 | Chorioretinal atrophy (HP:0000533) | 1.82385425 |
| 81 | Pancreatic cysts (HP:0001737) | 1.81803632 |
| 82 | Fatigue (HP:0012378) | 1.81660155 |
| 83 | Duodenal stenosis (HP:0100867) | 1.81561966 |
| 84 | Small intestinal stenosis (HP:0012848) | 1.81561966 |
| 85 | Hyperglycinuria (HP:0003108) | 1.80490287 |
| 86 | Acute necrotizing encephalopathy (HP:0006965) | 1.80195753 |
| 87 | Clubbing of toes (HP:0100760) | 1.80092965 |
| 88 | Abnormality of the renal collecting system (HP:0004742) | 1.79587632 |
| 89 | Attenuation of retinal blood vessels (HP:0007843) | 1.79124203 |
| 90 | Abnormality of chromosome stability (HP:0003220) | 1.78954455 |
| 91 | Myositis (HP:0100614) | 1.77936591 |
| 92 | Stomatitis (HP:0010280) | 1.77650968 |
| 93 | Type II lissencephaly (HP:0007260) | 1.75975888 |
| 94 | Increased serum pyruvate (HP:0003542) | 1.75679398 |
| 95 | Mitochondrial inheritance (HP:0001427) | 1.73579312 |
| 96 | Areflexia of lower limbs (HP:0002522) | 1.73539320 |
| 97 | Abnormality of midbrain morphology (HP:0002418) | 1.72213584 |
| 98 | Molar tooth sign on MRI (HP:0002419) | 1.72213584 |
| 99 | Status epilepticus (HP:0002133) | 1.71442597 |
| 100 | Embryonal neoplasm (HP:0002898) | 1.71212203 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 6.03535580 |
| 2 | MST4 | 5.99574238 |
| 3 | ADRBK2 | 5.48816141 |
| 4 | DYRK3 | 4.42556258 |
| 5 | GRK1 | 3.62842564 |
| 6 | FRK | 3.14879469 |
| 7 | ZAK | 2.87712174 |
| 8 | EIF2AK3 | 2.62077702 |
| 9 | MAPKAPK3 | 2.34692569 |
| 10 | STK39 | 2.27155779 |
| 11 | WNK4 | 2.20234942 |
| 12 | EIF2AK1 | 2.01695841 |
| 13 | ERN1 | 1.89353756 |
| 14 | STK10 | 1.66632538 |
| 15 | VRK2 | 1.54496007 |
| 16 | ADRBK1 | 1.51649539 |
| 17 | PINK1 | 1.48494652 |
| 18 | TAF1 | 1.38793199 |
| 19 | OXSR1 | 1.37582773 |
| 20 | ACVR1B | 1.33708053 |
| 21 | TSSK6 | 1.33223393 |
| 22 | MAPKAPK5 | 1.12099688 |
| 23 | TAOK1 | 1.06920335 |
| 24 | MAP3K3 | 1.06019894 |
| 25 | NUAK1 | 1.05789776 |
| 26 | STK16 | 1.03523281 |
| 27 | PBK | 1.01784843 |
| 28 | CDC7 | 1.01669003 |
| 29 | NEK1 | 1.00049576 |
| 30 | PIK3CG | 0.97713269 |
| 31 | PIM2 | 0.93157515 |
| 32 | PRKCE | 0.92984371 |
| 33 | RPS6KA4 | 0.87428972 |
| 34 | SRPK1 | 0.86891510 |
| 35 | TTK | 0.83913030 |
| 36 | NME2 | 0.81152024 |
| 37 | TRPM7 | 0.78935614 |
| 38 | NEK9 | 0.78820660 |
| 39 | IRAK3 | 0.78396206 |
| 40 | EIF2AK2 | 0.77760350 |
| 41 | PLK1 | 0.77448263 |
| 42 | PNCK | 0.77057430 |
| 43 | PRKCI | 0.76386931 |
| 44 | WEE1 | 0.76079063 |
| 45 | BMPR1B | 0.75324437 |
| 46 | PRKCG | 0.75144255 |
| 47 | TNIK | 0.74221031 |
| 48 | EEF2K | 0.72549328 |
| 49 | BUB1 | 0.71360806 |
| 50 | MST1R | 0.70305119 |
| 51 | DAPK1 | 0.69588379 |
| 52 | PLK4 | 0.67815356 |
| 53 | RIPK1 | 0.65007733 |
| 54 | AURKB | 0.64623256 |
| 55 | MAP3K9 | 0.63002473 |
| 56 | PLK3 | 0.62012845 |
| 57 | PLK2 | 0.60345330 |
| 58 | MAP2K6 | 0.60248987 |
| 59 | TGFBR1 | 0.58788748 |
| 60 | MAPK11 | 0.58513285 |
| 61 | MAP3K8 | 0.56733906 |
| 62 | CCNB1 | 0.55614346 |
| 63 | VRK1 | 0.55011506 |
| 64 | MAPK13 | 0.49901853 |
| 65 | IRAK1 | 0.48854526 |
| 66 | GRK5 | 0.47776187 |
| 67 | MKNK2 | 0.47277116 |
| 68 | CAMK1G | 0.46914961 |
| 69 | ATR | 0.46539088 |
| 70 | CLK1 | 0.46187550 |
| 71 | AKT2 | 0.45472357 |
| 72 | MKNK1 | 0.45220047 |
| 73 | MAP3K11 | 0.42249456 |
| 74 | CAMK1D | 0.42116306 |
| 75 | RPS6KB2 | 0.41479035 |
| 76 | ERBB2 | 0.39661771 |
| 77 | CHEK2 | 0.39265800 |
| 78 | BRSK1 | 0.38658914 |
| 79 | NME1 | 0.37928937 |
| 80 | CAMK2A | 0.37430127 |
| 81 | TEC | 0.36543880 |
| 82 | CSNK1A1L | 0.36464176 |
| 83 | CSNK2A2 | 0.36304620 |
| 84 | CDK7 | 0.36190876 |
| 85 | MAP3K14 | 0.33380981 |
| 86 | CHEK1 | 0.28686924 |
| 87 | STK38L | 0.28543690 |
| 88 | ATM | 0.27641927 |
| 89 | MELK | 0.25805769 |
| 90 | CSNK2A1 | 0.24391594 |
| 91 | STK3 | 0.23954969 |
| 92 | NEK2 | 0.23431119 |
| 93 | FGFR1 | 0.22679926 |
| 94 | ITK | 0.21589564 |
| 95 | PRKCB | 0.21345472 |
| 96 | FLT3 | 0.18223095 |
| 97 | ABL2 | 0.17882928 |
| 98 | CDK19 | 0.17204846 |
| 99 | PRKACB | 0.16134736 |
| 100 | BRSK2 | 0.15081590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Olfactory transduction_Homo sapiens_hsa04740 | 3.69428796 |
| 2 | Phototransduction_Homo sapiens_hsa04744 | 3.66427382 |
| 3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.25319994 |
| 4 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.97281955 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 2.74701959 |
| 6 | Basal transcription factors_Homo sapiens_hsa03022 | 2.48652953 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.43897906 |
| 8 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.15113203 |
| 9 | Homologous recombination_Homo sapiens_hsa03440 | 2.12212310 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.07848264 |
| 11 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.04394141 |
| 12 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.96058180 |
| 13 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.91097383 |
| 14 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.89947642 |
| 15 | Sulfur relay system_Homo sapiens_hsa04122 | 1.79903812 |
| 16 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.78611532 |
| 17 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.76139514 |
| 18 | Base excision repair_Homo sapiens_hsa03410 | 1.75469790 |
| 19 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.67147593 |
| 20 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.63953949 |
| 21 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.53967714 |
| 22 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.50629589 |
| 23 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.47952141 |
| 24 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.47614913 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.45781371 |
| 26 | RNA degradation_Homo sapiens_hsa03018 | 1.40584628 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.38849641 |
| 28 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.38659976 |
| 29 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.33087083 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.32532412 |
| 31 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.29568503 |
| 32 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.25511109 |
| 33 | Morphine addiction_Homo sapiens_hsa05032 | 1.23334710 |
| 34 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.23147383 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.19817261 |
| 36 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.17481747 |
| 37 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.16268412 |
| 38 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.15009524 |
| 39 | ABC transporters_Homo sapiens_hsa02010 | 1.14534732 |
| 40 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.14269446 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.13628130 |
| 42 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.12354979 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.10609632 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.08465026 |
| 45 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.05897441 |
| 46 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.03510688 |
| 47 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.02769479 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.01790539 |
| 49 | Parkinsons disease_Homo sapiens_hsa05012 | 1.00423291 |
| 50 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.99684029 |
| 51 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.98840451 |
| 52 | Mismatch repair_Homo sapiens_hsa03430 | 0.96748534 |
| 53 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.96605249 |
| 54 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93315153 |
| 55 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.92989305 |
| 56 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.92815781 |
| 57 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.92374893 |
| 58 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.87506166 |
| 59 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.84944589 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.83867444 |
| 61 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.81100658 |
| 62 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.78495282 |
| 63 | Huntingtons disease_Homo sapiens_hsa05016 | 0.75731859 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75365438 |
| 65 | RNA transport_Homo sapiens_hsa03013 | 0.72925545 |
| 66 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.70569913 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67937905 |
| 68 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.66709833 |
| 69 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.65940677 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63791475 |
| 71 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62022144 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.60544630 |
| 73 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.59701799 |
| 74 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.59605704 |
| 75 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55792690 |
| 76 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.55195231 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.54538370 |
| 78 | Mineral absorption_Homo sapiens_hsa04978 | 0.52044327 |
| 79 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.51938424 |
| 80 | Taste transduction_Homo sapiens_hsa04742 | 0.49514162 |
| 81 | Allograft rejection_Homo sapiens_hsa05330 | 0.49438471 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.48290176 |
| 83 | Carbon metabolism_Homo sapiens_hsa01200 | 0.47975185 |
| 84 | Alzheimers disease_Homo sapiens_hsa05010 | 0.47233021 |
| 85 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.46443274 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.45423099 |
| 87 | Histidine metabolism_Homo sapiens_hsa00340 | 0.41942023 |
| 88 | Asthma_Homo sapiens_hsa05310 | 0.40559949 |
| 89 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.38010823 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.37234007 |
| 91 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.37165945 |
| 92 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.36131075 |
| 93 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35505040 |
| 94 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.33049355 |
| 95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.32415584 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.32382276 |
| 97 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.32200258 |
| 98 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.31791839 |
| 99 | Protein export_Homo sapiens_hsa03060 | 0.30346288 |
| 100 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.26898141 |

