RPL26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)9.70038040
2ribosomal small subunit biogenesis (GO:0042274)9.59073789
3* translational elongation (GO:0006414)8.74000266
4* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)8.56200479
5* cotranslational protein targeting to membrane (GO:0006613)8.40782314
6* protein targeting to ER (GO:0045047)8.40364273
7maturation of SSU-rRNA (GO:0030490)8.13026142
8* establishment of protein localization to endoplasmic reticulum (GO:0072599)8.03251069
9* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)7.99759738
10* cellular protein complex disassembly (GO:0043624)7.94749797
11* viral life cycle (GO:0019058)7.92118761
12* protein localization to endoplasmic reticulum (GO:0070972)7.84773591
13* translational initiation (GO:0006413)7.55233877
14* protein complex disassembly (GO:0043241)6.97083680
15* macromolecular complex disassembly (GO:0032984)6.50903529
16* ribosomal large subunit biogenesis (GO:0042273)6.45312939
17* nuclear-transcribed mRNA catabolic process (GO:0000956)5.64942167
18* protein targeting to membrane (GO:0006612)5.63064995
19* mRNA catabolic process (GO:0006402)5.35679208
20* translation (GO:0006412)5.32693025
21* ribonucleoprotein complex biogenesis (GO:0022613)5.13436022
22* RNA catabolic process (GO:0006401)4.99865592
23formation of translation preinitiation complex (GO:0001731)4.68070484
24* rRNA processing (GO:0006364)4.04406548
25mitotic chromosome condensation (GO:0007076)3.92176149
26* rRNA metabolic process (GO:0016072)3.92018909
27* establishment of protein localization to membrane (GO:0090150)3.84748300
28* cellular component biogenesis (GO:0044085)3.79754864
29regulation of translational fidelity (GO:0006450)3.58585348
30nuclear pore complex assembly (GO:0051292)3.54964079
31DNA strand elongation involved in DNA replication (GO:0006271)3.54231580
32DNA deamination (GO:0045006)3.52747033
33* protein targeting (GO:0006605)3.47381490
34* establishment of protein localization to organelle (GO:0072594)3.45049216
35mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.42756377
36ATP synthesis coupled proton transport (GO:0015986)3.41062350
37energy coupled proton transport, down electrochemical gradient (GO:0015985)3.41062350
38DNA unwinding involved in DNA replication (GO:0006268)3.40757813
39telomere maintenance via semi-conservative replication (GO:0032201)3.39262843
40establishment of integrated proviral latency (GO:0075713)3.36961055
41DNA strand elongation (GO:0022616)3.33378267
42ncRNA 3-end processing (GO:0043628)3.28621715
43heterochromatin organization (GO:0070828)3.23758159
44DNA replication initiation (GO:0006270)3.11551326
45myeloid cell homeostasis (GO:0002262)3.11062067
46spliceosomal snRNP assembly (GO:0000387)3.08689652
47nuclear pore organization (GO:0006999)3.06736683
48ribosome biogenesis (GO:0042254)3.03130599
49protein localization to chromosome, centromeric region (GO:0071459)2.96769051
50DNA topological change (GO:0006265)2.95373517
51negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.93922872
52spliceosomal complex assembly (GO:0000245)2.92033785
53pseudouridine synthesis (GO:0001522)2.91960449
54ribosome assembly (GO:0042255)2.91681943
55negative regulation of RNA splicing (GO:0033119)2.91361425
56telomere maintenance via recombination (GO:0000722)2.91031736
57* protein localization to membrane (GO:0072657)2.89462334
58nucleobase-containing small molecule interconversion (GO:0015949)2.85912282
59oxidative phosphorylation (GO:0006119)2.82879448
60* cellular component disassembly (GO:0022411)2.82584938
61transcription elongation from RNA polymerase III promoter (GO:0006385)2.79375700
62termination of RNA polymerase III transcription (GO:0006386)2.79375700
63UTP biosynthetic process (GO:0006228)2.78163226
64folic acid-containing compound biosynthetic process (GO:0009396)2.78056020
65chaperone-mediated protein transport (GO:0072321)2.77171280
66kinetochore organization (GO:0051383)2.77015785
67* gene expression (GO:0010467)2.76977781
68histone H2B ubiquitination (GO:0033523)2.75832684
69establishment of protein localization to mitochondrial membrane (GO:0090151)2.75570155
70mitotic recombination (GO:0006312)2.75533424
71negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.73012994
72negative regulation of ligase activity (GO:0051352)2.73012994
73* ncRNA processing (GO:0034470)2.72927363
74regulation of mitochondrial translation (GO:0070129)2.71912748
75positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.69977816
76telomere maintenance via telomere lengthening (GO:0010833)2.69744848
77establishment of viral latency (GO:0019043)2.69450405
78negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.69396805
79exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.69067466
80nucleotide-excision repair, DNA gap filling (GO:0006297)2.68053007
81regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.67269939
82protein localization to kinetochore (GO:0034501)2.66242528
83DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.65917310
84transcription-coupled nucleotide-excision repair (GO:0006283)2.65481000
85anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.64453601
86proteasome assembly (GO:0043248)2.63637025
87ribonucleoprotein complex assembly (GO:0022618)2.63187037
88signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.61680640
89intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.61680640
90GTP biosynthetic process (GO:0006183)2.60448586
91nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.59299833
92signal transduction involved in DNA damage checkpoint (GO:0072422)2.59122189
93signal transduction involved in DNA integrity checkpoint (GO:0072401)2.59122189
94termination of RNA polymerase I transcription (GO:0006363)2.58701487
95antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.58412347
96* protein localization to organelle (GO:0033365)2.58319473
97respiratory electron transport chain (GO:0022904)2.57836034
98nucleobase biosynthetic process (GO:0046112)2.57319128
99DNA replication checkpoint (GO:0000076)2.57274369
100signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.56393588
101signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.56393588
102signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.56393588
103DNA replication-dependent nucleosome assembly (GO:0006335)2.55038488
104DNA replication-dependent nucleosome organization (GO:0034723)2.55038488
105* ncRNA metabolic process (GO:0034660)2.54843447
106signal transduction involved in cell cycle checkpoint (GO:0072395)2.54334710
107chromatin remodeling at centromere (GO:0031055)2.52667859
108pore complex assembly (GO:0046931)2.52359890
109RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.49387936
110mRNA splicing, via spliceosome (GO:0000398)2.49387936
111RNA splicing, via transesterification reactions (GO:0000375)2.48811418
112transcription elongation from RNA polymerase I promoter (GO:0006362)2.48312666
113ribonucleoprotein complex subunit organization (GO:0071826)2.48021057
114termination of RNA polymerase II transcription (GO:0006369)2.47726263
115electron transport chain (GO:0022900)2.47462984
116CENP-A containing nucleosome assembly (GO:0034080)2.46536556
117mitotic sister chromatid segregation (GO:0000070)2.46477437
118chromatin assembly or disassembly (GO:0006333)2.45762478
119sister chromatid segregation (GO:0000819)2.40038674
120regulation of RNA export from nucleus (GO:0046831)2.39908653
121mitotic metaphase plate congression (GO:0007080)2.36994557
122chromatin assembly (GO:0031497)2.36376527
123regulation of translational initiation (GO:0006446)2.35544916
124pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.30319211
125regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.29712676
126DNA replication-independent nucleosome assembly (GO:0006336)2.29610550
127DNA replication-independent nucleosome organization (GO:0034724)2.29610550
128negative regulation of DNA repair (GO:0045738)2.28549645
129positive regulation of viral transcription (GO:0050434)2.25099656
130aerobic respiration (GO:0009060)2.24673790
131chromosome condensation (GO:0030261)2.24199575
132kinetochore assembly (GO:0051382)2.22971825
133* single-organism cellular localization (GO:1902580)2.17161177
134* viral transcription (GO:0019083)10.6320624
135* translational termination (GO:0006415)10.2207231

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.99894886
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.92424139
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.09630595
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.03777857
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.72922652
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.30794275
7* GABP_17652178_ChIP-ChIP_JURKAT_Human3.10402950
8* ETS1_20019798_ChIP-Seq_JURKAT_Human3.04263278
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.92938803
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.86886688
11E2F4_17652178_ChIP-ChIP_JURKAT_Human2.84556279
12FOXM1_23109430_ChIP-Seq_U2OS_Human2.78874765
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.77409519
14* XRN2_22483619_ChIP-Seq_HELA_Human2.76747295
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.71012427
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.67477777
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.56778402
18FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.56162445
19* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.47265419
20* VDR_23849224_ChIP-Seq_CD4+_Human2.26357636
21TP63_17297297_ChIP-ChIP_HaCaT_Human2.23683078
22* TTF2_22483619_ChIP-Seq_HELA_Human2.23652160
23* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.19852975
24CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.15969054
25DCP1A_22483619_ChIP-Seq_HELA_Human2.13758040
26ELF1_17652178_ChIP-ChIP_JURKAT_Human2.04969003
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.00299945
28* FOXP3_21729870_ChIP-Seq_TREG_Human1.95999680
29ELK1_19687146_ChIP-ChIP_HELA_Human1.95440652
30FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.94894246
31* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.94513051
32* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.92960287
33SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.91475182
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.87194723
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.82202947
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.73643807
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68077288
38GABP_19822575_ChIP-Seq_HepG2_Human1.61601049
39ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.59577249
40MYC_22102868_ChIP-Seq_BL_Human1.55565130
41KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.53019811
42E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.51105657
43* THAP11_20581084_ChIP-Seq_MESCs_Mouse1.49476138
44NANOG_18555785_ChIP-Seq_MESCs_Mouse1.48176479
45HOXB4_20404135_ChIP-ChIP_EML_Mouse1.46067968
46* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42152137
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.40029307
48E2F1_21310950_ChIP-Seq_MCF-7_Human1.39607249
49YY1_21170310_ChIP-Seq_MESCs_Mouse1.39403068
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.37262633
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37166411
52KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.36170891
53* ELK1_22589737_ChIP-Seq_MCF10A_Human1.34700115
54CIITA_25753668_ChIP-Seq_RAJI_Human1.34344471
55POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.33328024
56CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.32731779
57STAT3_1855785_ChIP-Seq_MESCs_Mouse1.32603410
58* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.31843942
59VDR_21846776_ChIP-Seq_THP-1_Human1.31233312
60AR_21909140_ChIP-Seq_LNCAP_Human1.30411144
61MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.30266012
62TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.29532913
63* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29516750
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.28317197
65EGR1_19374776_ChIP-ChIP_THP-1_Human1.27526900
66* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.26660159
67SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.26279441
68KDM5A_27292631_Chip-Seq_BREAST_Human1.26112185
69TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.24586600
70KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.23073358
71SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.20869371
72* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.19215733
73SOX2_18555785_ChIP-Seq_MESCs_Mouse1.17323010
74MYC_18940864_ChIP-ChIP_HL60_Human1.16812795
75KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.16277155
76KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.16277155
77KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.16277155
78ESR1_15608294_ChIP-ChIP_MCF-7_Human1.15209329
79CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.12530202
80YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.12306795
81* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.12146014
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.10723294
83KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09069857
84CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.06820046
85ZNF263_19887448_ChIP-Seq_K562_Human1.06752490
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.06378816
87SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.06251212
88TCF3_18692474_ChIP-Seq_MEFs_Mouse1.05402314
89* SRF_21415370_ChIP-Seq_HL-1_Mouse1.05096277
90HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.05006917
91PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.04879740
92* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.04552639
93OCT4_18692474_ChIP-Seq_MEFs_Mouse1.03923975
94NANOG_21062744_ChIP-ChIP_HESCs_Human1.03109299
95* SPI1_23547873_ChIP-Seq_NB4_Human1.02740365
96CHD1_26751641_Chip-Seq_LNCaP_Human1.02563700
97HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.01248643
98ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.00571003
99ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.00500543
100TP63_19390658_ChIP-ChIP_HaCaT_Human0.98649797
101ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.98309639
102BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.97558868
103SRY_22984422_ChIP-ChIP_TESTIS_Rat0.96893582
104SOX2_18692474_ChIP-Seq_MEFs_Mouse0.96044136
105PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.94124580
106TFEB_21752829_ChIP-Seq_HELA_Human0.93309572
107NOTCH1_21737748_ChIP-Seq_TLL_Human0.93298941
108IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.90457506
109TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.89617481
110* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.89423637
111SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.89006871
112MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.88063680
113SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87866401
114PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.85911571
115PADI4_21655091_ChIP-ChIP_MCF-7_Human0.82325242
116GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.81939708

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.97907600
2MP0003693_abnormal_embryo_hatching4.61698320
3MP0004957_abnormal_blastocyst_morpholog3.92006652
4MP0010094_abnormal_chromosome_stability3.03551283
5MP0003077_abnormal_cell_cycle3.03054083
6MP0003111_abnormal_nucleus_morphology2.89613047
7MP0006292_abnormal_olfactory_placode2.56528805
8MP0008057_abnormal_DNA_replication2.25246366
9MP0010352_gastrointestinal_tract_polyps2.24793275
10MP0008932_abnormal_embryonic_tissue2.21722747
11MP0002396_abnormal_hematopoietic_system2.10772885
12MP0008058_abnormal_DNA_repair2.08038601
13MP0000490_abnormal_crypts_of2.04216361
14MP0008007_abnormal_cellular_replicative1.92577171
15MP0004185_abnormal_adipocyte_glucose1.88785377
16MP0003786_premature_aging1.86618726
17MP0001730_embryonic_growth_arrest1.75281875
18MP0000350_abnormal_cell_proliferation1.73763101
19MP0003136_yellow_coat_color1.68566954
20MP0009333_abnormal_splenocyte_physiolog1.61917971
21MP0002697_abnormal_eye_size1.61564571
22MP0000566_synostosis1.60586235
23MP0003315_abnormal_perineum_morphology1.58684919
24MP0010030_abnormal_orbit_morphology1.55534811
25MP0003567_abnormal_fetal_cardiomyocyte1.54653167
26MP0004808_abnormal_hematopoietic_stem1.50008928
27MP0001286_abnormal_eye_development1.48896920
28MP0003123_paternal_imprinting1.48059062
29MP0003763_abnormal_thymus_physiology1.44802398
30MP0000537_abnormal_urethra_morphology1.41700812
31MP0002796_impaired_skin_barrier1.35504713
32MP0003941_abnormal_skin_development1.33579062
33MP0005408_hypopigmentation1.32957279
34MP0002166_altered_tumor_susceptibility1.32781524
35MP0002877_abnormal_melanocyte_morpholog1.31048487
36MP0002019_abnormal_tumor_incidence1.30890626
37MP0005501_abnormal_skin_physiology1.30601225
38MP0001697_abnormal_embryo_size1.27339757
39MP0002092_abnormal_eye_morphology1.27102820
40MP0000703_abnormal_thymus_morphology1.25561257
41MP0003705_abnormal_hypodermis_morpholog1.25459185
42MP0002398_abnormal_bone_marrow1.23826233
43MP0002722_abnormal_immune_system1.23608552
44MP0002080_prenatal_lethality1.22861760
45MP0000313_abnormal_cell_death1.22466889
46MP0009053_abnormal_anal_canal1.22242975
47MP0002132_abnormal_respiratory_system1.19286974
48MP0010234_abnormal_vibrissa_follicle1.18167136
49MP0001346_abnormal_lacrimal_gland1.15483643
50MP0001545_abnormal_hematopoietic_system1.14429200
51MP0005397_hematopoietic_system_phenotyp1.14429200
52MP0000685_abnormal_immune_system1.12863169
53MP0005174_abnormal_tail_pigmentation1.12581000
54MP0002085_abnormal_embryonic_tissue1.10866573
55MP0000689_abnormal_spleen_morphology1.09876968
56MP0001800_abnormal_humoral_immune1.09834935
57MP0003890_abnormal_embryonic-extraembry1.09447819
58MP0002084_abnormal_developmental_patter1.08878047
59MP0000465_gastrointestinal_hemorrhage1.08768877
60MP0004381_abnormal_hair_follicle1.08593472
61MP0005380_embryogenesis_phenotype1.08517079
62MP0001672_abnormal_embryogenesis/_devel1.08517079
63MP0002006_tumorigenesis1.08144991
64MP0004197_abnormal_fetal_growth/weight/1.08025857
65MP0000762_abnormal_tongue_morphology1.07330770
66MP0002009_preneoplasia1.06802067
67MP0002938_white_spotting1.06124146
68MP0003718_maternal_effect1.05031521
69MP0002086_abnormal_extraembryonic_tissu1.04471482
70MP0003806_abnormal_nucleotide_metabolis1.02426482
71MP0001835_abnormal_antigen_presentation1.02214424
72MP0009672_abnormal_birth_weight1.02119753
73MP0002429_abnormal_blood_cell1.00985324
74MP0000428_abnormal_craniofacial_morphol1.00256749
75MP0001853_heart_inflammation0.99106525
76MP0000858_altered_metastatic_potential0.98940541
77MP0006054_spinal_hemorrhage0.98309938
78MP0010307_abnormal_tumor_latency0.96964764
79MP0002160_abnormal_reproductive_system0.96084646
80MP0001873_stomach_inflammation0.95955342
81MP0002210_abnormal_sex_determination0.95366316
82MP0003942_abnormal_urinary_system0.94290522
83MP0002095_abnormal_skin_pigmentation0.94200937
84MP0003937_abnormal_limbs/digits/tail_de0.94145157
85MP0005023_abnormal_wound_healing0.94088112
86MP0000716_abnormal_immune_system0.93319082
87MP0002405_respiratory_system_inflammati0.93121990
88MP0002420_abnormal_adaptive_immunity0.93105038
89MP0003385_abnormal_body_wall0.92511104
90MP0001216_abnormal_epidermal_layer0.92097331
91MP0002277_abnormal_respiratory_mucosa0.92034026
92MP0010155_abnormal_intestine_physiology0.91962629
93MP0002088_abnormal_embryonic_growth/wei0.91807633
94MP0005076_abnormal_cell_differentiation0.91676159
95MP0003984_embryonic_growth_retardation0.91474398
96MP0005666_abnormal_adipose_tissue0.91281663
97MP0001819_abnormal_immune_cell0.91233638
98MP0001293_anophthalmia0.91058528
99MP0008995_early_reproductive_senescence0.90593383
100MP0002452_abnormal_antigen_presenting0.90262417
101MP0002249_abnormal_larynx_morphology0.88837646
102MP0003938_abnormal_ear_development0.88510853
103MP0003866_abnormal_defecation0.88193834
104MP0000477_abnormal_intestine_morphology0.87860697
105MP0009278_abnormal_bone_marrow0.86893247
106MP0000358_abnormal_cell_content/0.84736008
107MP0002233_abnormal_nose_morphology0.84583894
108MP0003186_abnormal_redox_activity0.82631247
109MP0000049_abnormal_middle_ear0.82624218
110MP0000372_irregular_coat_pigmentation0.82196527
111MP0002060_abnormal_skin_morphology0.81821885
112MP0002111_abnormal_tail_morphology0.80083931
113MP0005671_abnormal_response_to0.79985243
114MP0002723_abnormal_immune_serum0.79632317
115MP0002098_abnormal_vibrissa_morphology0.79458024
116MP0001727_abnormal_embryo_implantation0.78788442
117MP0002163_abnormal_gland_morphology0.78638525
118MP0005025_abnormal_response_to0.77302346
119MP0000750_abnormal_muscle_regeneration0.77284727
120MP0003861_abnormal_nervous_system0.76092642
121MP0004133_heterotaxia0.75292941
122MP0001881_abnormal_mammary_gland0.74946390
123MP0003436_decreased_susceptibility_to0.74675048
124MP0001340_abnormal_eyelid_morphology0.74167245
125MP0001145_abnormal_male_reproductive0.73996568
126MP0001348_abnormal_lacrimal_gland0.73908831
127MP0003453_abnormal_keratinocyte_physiol0.73855720
128MP0003755_abnormal_palate_morphology0.73840327
129MP0008789_abnormal_olfactory_epithelium0.73558538
130MP0000678_abnormal_parathyroid_gland0.73336958
131MP0005000_abnormal_immune_tolerance0.72994516
132MP0005075_abnormal_melanosome_morpholog0.72215290
133MP0003566_abnormal_cell_adhesion0.71822457
134MP0009250_abnormal_appendicular_skeleto0.69429970
135MP0005193_abnormal_anterior_eye0.67885578
136MP0005394_taste/olfaction_phenotype0.66766444
137MP0005499_abnormal_olfactory_system0.66766444
138MP0003121_genomic_imprinting0.66695172
139MP0002114_abnormal_axial_skeleton0.66407951
140MP0000733_abnormal_muscle_development0.65555469
141MP0006035_abnormal_mitochondrial_morpho0.65241499
142MP0001188_hyperpigmentation0.62858324
143MP0002638_abnormal_pupillary_reflex0.62189963
144MP0004264_abnormal_extraembryonic_tissu0.61369741

Predicted human phenotypes

RankGene SetZ-score
1Abnormal number of erythroid precursors (HP:0012131)9.33152256
2* Abnormality of cells of the erythroid lineage (HP:0012130)9.33152256
3Reticulocytopenia (HP:0001896)9.09867421
4* Macrocytic anemia (HP:0001972)6.54264982
5* Pallor (HP:0000980)5.95996010
6Abnormal hemoglobin (HP:0011902)4.10545519
7Colon cancer (HP:0003003)3.72290344
8Thrombocytosis (HP:0001894)3.44446839
9Aplasia/Hypoplasia of the sacrum (HP:0008517)3.32248743
10Aplastic anemia (HP:0001915)3.26236097
11Oral leukoplakia (HP:0002745)3.14104060
12Abnormality of reticulocytes (HP:0004312)3.10738354
1311 pairs of ribs (HP:0000878)3.04315738
14Trismus (HP:0000211)2.96772144
15Congenital, generalized hypertrichosis (HP:0004540)2.96148740
16Multiple enchondromatosis (HP:0005701)2.84802304
17Abnormality of the parietal bone (HP:0002696)2.83800460
18Chromsome breakage (HP:0040012)2.76078157
19Increased hepatocellular lipid droplets (HP:0006565)2.71977714
20Selective tooth agenesis (HP:0001592)2.69009161
21* Depressed nasal ridge (HP:0000457)2.64261661
22Birth length less than 3rd percentile (HP:0003561)2.61179284
23Asplenia (HP:0001746)2.61156471
24Deep palmar crease (HP:0006191)2.59951754
25Duplication of thumb phalanx (HP:0009942)2.58507623
26Chromosomal breakage induced by crosslinking agents (HP:0003221)2.55653302
27Woolly hair (HP:0002224)2.46584136
28Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.43885067
29Decreased activity of mitochondrial respiratory chain (HP:0008972)2.43885067
30Rough bone trabeculation (HP:0100670)2.41887365
31Breast hypoplasia (HP:0003187)2.41581213
32Carpal bone hypoplasia (HP:0001498)2.41385117
33Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.40398332
34Acute necrotizing encephalopathy (HP:0006965)2.38510825
35Aplasia/Hypoplasia of the spleen (HP:0010451)2.35047244
36Exertional dyspnea (HP:0002875)2.32299488
37Mitochondrial inheritance (HP:0001427)2.31547076
38Microretrognathia (HP:0000308)2.31010168
39Basal cell carcinoma (HP:0002671)2.30849246
40IgM deficiency (HP:0002850)2.29964003
41Lipid accumulation in hepatocytes (HP:0006561)2.25760638
42* Migraine (HP:0002076)2.25520263
43Glossoptosis (HP:0000162)2.24956747
44* Thick lower lip vermilion (HP:0000179)2.24265836
45Cerebral edema (HP:0002181)2.18620791
46Calcaneovalgus deformity (HP:0001848)2.17712461
47Triphalangeal thumb (HP:0001199)2.15946523
48Missing ribs (HP:0000921)2.15731602
49Neoplasm of the pancreas (HP:0002894)2.13172660
50* Absent thumb (HP:0009777)2.11899433
51Abnormality of DNA repair (HP:0003254)2.10497548
52Abnormal number of incisors (HP:0011064)2.09791543
53Septo-optic dysplasia (HP:0100842)2.08188101
54Myelodysplasia (HP:0002863)2.06802747
55Abnormality of cochlea (HP:0000375)2.04245337
56Respiratory difficulties (HP:0002880)2.03635683
57Abnormal mitochondria in muscle tissue (HP:0008316)2.03435809
58Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.01099967
59Cleft eyelid (HP:0000625)1.99314638
60Microvesicular hepatic steatosis (HP:0001414)1.97581328
61Fragile nails (HP:0001808)1.97329712
62Abnormality of the calcaneus (HP:0008364)1.95467882
63Squamous cell carcinoma (HP:0002860)1.94697666
64Increased CSF lactate (HP:0002490)1.93946036
65Diastasis recti (HP:0001540)1.91702176
66Patellar aplasia (HP:0006443)1.91410933
67Horseshoe kidney (HP:0000085)1.90951543
68Facial cleft (HP:0002006)1.89224625
69Nasolacrimal duct obstruction (HP:0000579)1.88372394
70Progressive macrocephaly (HP:0004481)1.88075939
71Premature graying of hair (HP:0002216)1.85773103
72Hepatocellular necrosis (HP:0001404)1.84879237
73Overriding aorta (HP:0002623)1.84226442
74Ependymoma (HP:0002888)1.84105570
75Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.83808429
76Deformed tarsal bones (HP:0008119)1.83705351
77Dysphonia (HP:0001618)1.83690437
78Spinal cord lesions (HP:0100561)1.83687544
79Syringomyelia (HP:0003396)1.83687544
80Abnormality of the preputium (HP:0100587)1.83624793
81Poikiloderma (HP:0001029)1.83418434
82Sparse eyelashes (HP:0000653)1.83242600
83Insomnia (HP:0100785)1.83009970
84Aplasia/Hypoplasia of the patella (HP:0006498)1.82736771
85Progressive external ophthalmoplegia (HP:0000590)1.82509216
86Increased muscle lipid content (HP:0009058)1.81780825
87Absent radius (HP:0003974)1.80366665
88Cellular immunodeficiency (HP:0005374)1.79281153
89Hyperacusis (HP:0010780)1.79168092
90Renal duplication (HP:0000075)1.78411953
91Agnosia (HP:0010524)1.78262391
92Partial duplication of thumb phalanx (HP:0009944)1.77479953
93Abnormality of the axillary hair (HP:0100134)1.77229360
94Abnormality of secondary sexual hair (HP:0009888)1.77229360
95Renal Fanconi syndrome (HP:0001994)1.76434897
96Premature ovarian failure (HP:0008209)1.74575531
97Chronic otitis media (HP:0000389)1.74555440
98Mesangial abnormality (HP:0001966)1.73992105
99Increased nuchal translucency (HP:0010880)1.72908303
100Increased intramyocellular lipid droplets (HP:0012240)1.72724163
101Tracheoesophageal fistula (HP:0002575)1.71377405
1023-Methylglutaconic aciduria (HP:0003535)1.71070221
103Broad distal phalanx of finger (HP:0009836)1.70436404
104Medulloblastoma (HP:0002885)1.70427511
105Pili torti (HP:0003777)1.70303683
106Partial duplication of the phalanx of hand (HP:0009999)1.69112699
107Abnormal trabecular bone morphology (HP:0100671)1.68956118
108Absent forearm bone (HP:0003953)1.67293409
109Aplasia involving forearm bones (HP:0009822)1.67293409
110* Short nose (HP:0003196)1.66422069
111Colitis (HP:0002583)1.66396415
112Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.66114943
113Pancytopenia (HP:0001876)1.65918725
114Overlapping toe (HP:0001845)1.65884602
115Acute encephalopathy (HP:0006846)1.65591433
116Elfin facies (HP:0004428)1.63937325
117Supernumerary spleens (HP:0009799)1.63606577
118Concave nail (HP:0001598)1.62146103
119Rib fusion (HP:0000902)1.62003033
120Deep philtrum (HP:0002002)1.61674725
121Recurrent bronchitis (HP:0002837)1.61452277
122Petechiae (HP:0000967)1.61436212
123Amaurosis fugax (HP:0100576)1.61331879
124Exercise intolerance (HP:0003546)1.60938742
125High anterior hairline (HP:0009890)1.60935848
126Congenital ichthyosiform erythroderma (HP:0007431)1.60313402
127Progressive muscle weakness (HP:0003323)1.60228590
128Lymphoma (HP:0002665)1.59579339
129Thoracic kyphosis (HP:0002942)1.59367319
130Abnormality of the lacrimal duct (HP:0011481)1.58427645
131Abnormality of the phalanges of the hallux (HP:0010057)1.58315831
132Proximal placement of thumb (HP:0009623)1.57314219
133Esophageal atresia (HP:0002032)1.56437297
134Abnormality of the septum pellucidum (HP:0007375)1.55259027
135Leukodystrophy (HP:0002415)1.54252361
136Abnormality of small intestinal villus morphology (HP:0011472)1.54040280
137Villous atrophy (HP:0011473)1.54040280
138Meckel diverticulum (HP:0002245)1.53975407
139Abnormality of the thoracic spine (HP:0100711)1.53676605
140* Atresia of the external auditory canal (HP:0000413)1.52902729
141Cerebral hypomyelination (HP:0006808)1.52792612
142Abnormality of the distal phalanx of the thumb (HP:0009617)1.52202775
143Absent septum pellucidum (HP:0001331)1.50864435
144Pseudobulbar signs (HP:0002200)1.47602262
145Short middle phalanx of the 5th finger (HP:0004220)1.47043480
146Nephroblastoma (Wilms tumor) (HP:0002667)1.45284436
147Acute lymphatic leukemia (HP:0006721)1.44794833

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME25.72036221
2BUB13.55393998
3RPS6KB23.47845055
4WEE13.18777793
5EEF2K2.89751126
6LRRK22.68979095
7TLK12.57832687
8VRK22.53082259
9SMG12.49570027
10CDC72.43790927
11TGFBR12.31286729
12PASK2.17500289
13EIF2AK12.05741394
14SRPK12.04596787
15MST42.04332626
16VRK11.87793565
17PRPF4B1.85611462
18BRAF1.75540506
19PIM21.74028319
20TAF11.73046660
21NEK21.71367669
22EIF2AK31.71175255
23DYRK31.69552384
24TRIB31.67392997
25STK161.67018157
26AURKB1.53408297
27MKNK11.47755191
28MAP4K11.47249125
29ILK1.46299047
30MAPKAPK31.42608014
31CDK71.38949815
32EPHA21.38397684
33MAP3K101.36196259
34TSSK61.35669862
35STK241.33668632
36TESK21.29687648
37LATS21.24365734
38PKN21.21676491
39ACVR1B1.18499881
40ARAF1.17469916
41RPS6KA41.17001566
42STK101.16590081
43PLK11.16427759
44MAP3K81.14831077
45MAP3K131.13217656
46ICK1.12650543
47NME11.09570134
48GRK61.09427493
49CDK191.08954676
50TTK1.08077928
51FLT31.07420363
52BRSK21.06034746
53PAK41.04100843
54AURKA1.01891403
55MAP2K30.99611794
56PIM10.96940380
57MAP2K20.96542728
58CDK40.92998779
59ZAK0.92950619
60MAP3K30.92564006
61ATR0.91598408
62BTK0.90924575
63SCYL20.90345648
64CSNK2A20.89345589
65KDR0.86686043
66TYRO30.82779806
67BRD40.82070909
68PLK40.81675845
69WNK40.80387008
70PDK20.78111040
71MKNK20.77991430
72TEC0.77788924
73PAK10.77372968
74RPS6KA50.76756870
75MAP3K90.70875312
76MST1R0.69639321
77CHEK10.69459584
78CHEK20.69385476
79PAK20.69168067
80STK30.67660668
81STK40.66837979
82CSNK2A10.66632443
83CDK60.65573520
84SIK10.65390070
85TYK20.64907498
86IKBKB0.63348794
87PIK3CA0.62422642
88MTOR0.61285549
89MAP3K110.60920724
90TESK10.60584079
91CDK10.58659535
92MAP3K120.58434686
93NEK10.56415695
94ZAP700.56406086
95PRKCI0.54706537
96KIT0.54135618
97LATS10.53220453
98WNK10.52699532
99PLK30.52132007
100BLK0.51800319
101PNCK0.50543677
102PBK0.47966821
103ALK0.47491844
104DYRK1B0.46903167
105DMPK0.46272485
106DAPK30.46048312
107CDK20.44880971
108CDK80.44878217
109MELK0.44327740
110IRAK30.43354734
111ATM0.42627329
112CDK11A0.42572137
113CSF1R0.42432889
114LIMK10.39363287
115BRSK10.39278350
116RPS6KB10.38770115
117EIF2AK20.36812936
118NLK0.35663770
119LCK0.35386421
120SYK0.34529749
121LYN0.34428562
122RPS6KC10.34207280
123RPS6KL10.34207280
124RPS6KA10.33982554
125MAPK140.33334744
126STK390.31795548
127CDK120.29469924
128RPS6KA60.29418997
129CSNK1E0.29182385
130EPHB20.29142702
131MAPKAPK20.29134971
132AKT20.28799579
133CDK90.26954257
134DYRK20.26718429
135MET0.26066366

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030108.30390421
2DNA replication_Homo sapiens_hsa030303.75024882
3Proteasome_Homo sapiens_hsa030503.44976343
4Mismatch repair_Homo sapiens_hsa034303.33615470
5RNA polymerase_Homo sapiens_hsa030203.25740299
6Spliceosome_Homo sapiens_hsa030403.13093406
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.81468742
8RNA transport_Homo sapiens_hsa030132.37902812
9Nucleotide excision repair_Homo sapiens_hsa034202.37400579
10Homologous recombination_Homo sapiens_hsa034402.28484735
11Pyrimidine metabolism_Homo sapiens_hsa002402.27825654
12Base excision repair_Homo sapiens_hsa034102.06112380
13Oxidative phosphorylation_Homo sapiens_hsa001901.95956430
14Parkinsons disease_Homo sapiens_hsa050121.92270508
15One carbon pool by folate_Homo sapiens_hsa006701.73019344
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.67038006
17Cell cycle_Homo sapiens_hsa041101.59640331
18Huntingtons disease_Homo sapiens_hsa050161.55395421
19RNA degradation_Homo sapiens_hsa030181.49377043
20Systemic lupus erythematosus_Homo sapiens_hsa053221.47534373
21Non-homologous end-joining_Homo sapiens_hsa034501.46910487
22Fanconi anemia pathway_Homo sapiens_hsa034601.46489422
23Protein export_Homo sapiens_hsa030601.43827526
24Basal transcription factors_Homo sapiens_hsa030221.33996580
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.26593782
26p53 signaling pathway_Homo sapiens_hsa041151.23117954
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.20717582
28Alzheimers disease_Homo sapiens_hsa050101.18634056
29mRNA surveillance pathway_Homo sapiens_hsa030151.10752316
30Purine metabolism_Homo sapiens_hsa002301.05848930
31Epstein-Barr virus infection_Homo sapiens_hsa051691.04649500
32Antigen processing and presentation_Homo sapiens_hsa046120.97084286
33Sulfur relay system_Homo sapiens_hsa041220.96483785
34Cyanoamino acid metabolism_Homo sapiens_hsa004600.96345502
35Primary immunodeficiency_Homo sapiens_hsa053400.89304614
36Herpes simplex infection_Homo sapiens_hsa051680.77169849
37Viral carcinogenesis_Homo sapiens_hsa052030.77168721
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.74202114
39Carbon metabolism_Homo sapiens_hsa012000.73149138
40Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70948335
41Pyruvate metabolism_Homo sapiens_hsa006200.69323504
42Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.69320577
43Pancreatic cancer_Homo sapiens_hsa052120.65086739
44Alcoholism_Homo sapiens_hsa050340.64528959
45Folate biosynthesis_Homo sapiens_hsa007900.63117821
46Transcriptional misregulation in cancer_Homo sapiens_hsa052020.61229752
47HTLV-I infection_Homo sapiens_hsa051660.60299984
48Thyroid cancer_Homo sapiens_hsa052160.60111580
49Hematopoietic cell lineage_Homo sapiens_hsa046400.58723098
50Glutathione metabolism_Homo sapiens_hsa004800.58371275
51Non-small cell lung cancer_Homo sapiens_hsa052230.54770073
52Renal cell carcinoma_Homo sapiens_hsa052110.51582098
53Basal cell carcinoma_Homo sapiens_hsa052170.51572652
54Small cell lung cancer_Homo sapiens_hsa052220.51018927
55Pentose phosphate pathway_Homo sapiens_hsa000300.50682961
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.49901369
57Legionellosis_Homo sapiens_hsa051340.46906159
58Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.46187073
59Apoptosis_Homo sapiens_hsa042100.45998791
60Intestinal immune network for IgA production_Homo sapiens_hsa046720.43177616
61NF-kappa B signaling pathway_Homo sapiens_hsa040640.41955586
62Wnt signaling pathway_Homo sapiens_hsa043100.41952558
63Bladder cancer_Homo sapiens_hsa052190.38267116
64Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.38077948
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37066283
66Prostate cancer_Homo sapiens_hsa052150.35327036
67MicroRNAs in cancer_Homo sapiens_hsa052060.35153451
68Acute myeloid leukemia_Homo sapiens_hsa052210.35017649
69Arachidonic acid metabolism_Homo sapiens_hsa005900.34821827
70Cardiac muscle contraction_Homo sapiens_hsa042600.32997755
71Notch signaling pathway_Homo sapiens_hsa043300.32988885
72Measles_Homo sapiens_hsa051620.32840071
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.31884498
74Hedgehog signaling pathway_Homo sapiens_hsa043400.31724503
75NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31188432
76Pathways in cancer_Homo sapiens_hsa052000.30797158
77Asthma_Homo sapiens_hsa053100.29929090
78HIF-1 signaling pathway_Homo sapiens_hsa040660.28571578
79Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.28529148
80TGF-beta signaling pathway_Homo sapiens_hsa043500.28340119
81Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27966129
82Shigellosis_Homo sapiens_hsa051310.27413023
83N-Glycan biosynthesis_Homo sapiens_hsa005100.26850643
84Galactose metabolism_Homo sapiens_hsa000520.26759153
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.26679180
86Endometrial cancer_Homo sapiens_hsa052130.26628724
87Oocyte meiosis_Homo sapiens_hsa041140.26612448
88mTOR signaling pathway_Homo sapiens_hsa041500.26238290
89Chronic myeloid leukemia_Homo sapiens_hsa052200.25762960
90VEGF signaling pathway_Homo sapiens_hsa043700.25571301
91B cell receptor signaling pathway_Homo sapiens_hsa046620.25383417
92Hepatitis B_Homo sapiens_hsa051610.22883654
93Metabolic pathways_Homo sapiens_hsa011000.22462038
94Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21901950
95Jak-STAT signaling pathway_Homo sapiens_hsa046300.21884267
96Colorectal cancer_Homo sapiens_hsa052100.21468872
97Leukocyte transendothelial migration_Homo sapiens_hsa046700.20965164
98Linoleic acid metabolism_Homo sapiens_hsa005910.20950012
99Biosynthesis of amino acids_Homo sapiens_hsa012300.20359979
100RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.20314776
101Melanoma_Homo sapiens_hsa052180.20264517
102Hippo signaling pathway_Homo sapiens_hsa043900.20066844
103Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.19922372
104ErbB signaling pathway_Homo sapiens_hsa040120.19830373
105Allograft rejection_Homo sapiens_hsa053300.19738555
106Adherens junction_Homo sapiens_hsa045200.17796417
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.17568011
108Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.15893620
109T cell receptor signaling pathway_Homo sapiens_hsa046600.15880241
110Leishmaniasis_Homo sapiens_hsa051400.15478265
111Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.15449683
112Cysteine and methionine metabolism_Homo sapiens_hsa002700.15314389
113Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.14935401
114Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.14651823
115Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.14279667
116Selenocompound metabolism_Homo sapiens_hsa004500.13891684
117Influenza A_Homo sapiens_hsa051640.13861299
118Toxoplasmosis_Homo sapiens_hsa051450.12878662
119Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.12124726
120Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.12087970
121Central carbon metabolism in cancer_Homo sapiens_hsa052300.11646531
122Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.11397272
123Thyroid hormone signaling pathway_Homo sapiens_hsa049190.11182037
1242-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.10286174
125Prion diseases_Homo sapiens_hsa050200.09889140
126Neurotrophin signaling pathway_Homo sapiens_hsa047220.09594684
127Lysine degradation_Homo sapiens_hsa003100.09563014

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